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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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February-2021 Volume 23 Issue 2

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Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

Co‑expression of tissue kallikrein 1 and tissue inhibitor of matrix metalloproteinase 1 improves myocardial ischemia‑reperfusion injury by promoting angiogenesis and inhibiting oxidative stress

Shujie Huang, Meixian Chen, Huizhen Yu, Kaiyang Lin, Yansong Guo, Pengli Zhu
Article Number: 166
Published online on: 22 December 2020

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Article Open Access

miR‑126 overexpression attenuates oxygen‑glucose deprivation/reperfusion injury by inhibiting oxidative stress and inflammatory response via the activation of SIRT1/Nrf2 signaling pathway in human umbilical vein endothelial cells Corrigendum in /10.3892/mmr.2021.12158

Jixin Li, Caili Yang, Yan Wang
Article Number: 165
Published online on: 22 December 2020

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Article Open Access

S100A16 suppresses the proliferation, migration and invasion of colorectal cancer cells in part via the JNK/p38 MAPK pathway

Shiyu Ou, Yan Liao, Jie Shi, Jing Tang, Yanqing Ye, Fengfei Wu, Weidong Wang, Jieying Fei, Fang Xie, Lan Bai
Article Number: 164
Published online on: 22 December 2020

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Article

Effects of KAI gene expression on ferroptosis in pancreatic cancer cells

Xu Liu, Xiaozhong Guo, Hongyu Li, Jiang Chen, Hao Han
Article Number: 163
Published online on: 22 December 2020

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Article Open Access

Induction of notochordal differentiation of bone marrow mesenchymal‑derived stem cells via the stimulation of notochordal cell‑rich nucleus pulposus tissue

Defang Li, Qingmin Zeng, Zengxin Jiang, Lei Ding, Wei Lu, Mengxuan Bian, Jingping Wu
Article Number: 162
Published online on: 22 December 2020

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Article Open Access

Mitochondrial proteomics alterations in rat hearts following ischemia/reperfusion and diazoxide post‑conditioning

Yunchao Pan, Yuan Wang, Wenyan Shi, Yun Liu, Song Cao, Tian Yu
Article Number: 161
Published online on: 22 December 2020

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Article Open Access

Age affects the paracrine activity and differentiation potential of human adipose‑derived stem cells

Jeong Seop Park, Gabee Park, Hyun Sook Hong
Article Number: 160
Published online on: 22 December 2020

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Review

Role of peroxisome proliferator-activated receptors in osteoarthritis (Review)

Gang Huang, Wei Jiang, Weiyong Xie, Wei Lu, Weimin Zhu, Zhenhan Deng
Article Number: 159
Published online on: 22 December 2020

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Article

Neochlorogenic acid enhances the antitumor effects of pingyangmycin via regulating TOP2A

Jianhuan Che, Tongxia Zhao, Wen Liu, Shi Chen, Guangyu Yang, Xinyan Li, Dongling Liu
Article Number: 158
Published online on: 22 December 2020

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Article Open Access

Luteolin attenuates angiotensin II‑induced renal damage in apolipoprotein E‑deficient mice

Ying-Shu Liu, Qin Yang, Shen Li, Lan Luo, Hong-Yang Liu, Xin-Yu Li, Zheng-Nan Gao
Article Number: 157
Published online on: 22 December 2020

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Review

Estrogen receptor-associated receptor α and peroxisome proliferator-activated receptor γ in metabolism and disease (Review)

Wei-Yi Huang, Peng-Ming Sun
Article Number: 156
Published online on: 22 December 2020

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Article Open Access

Isoflurane reduces septic neuron injury by HO‑1‑mediated abatement of inflammation and apoptosis

Lina Zhang, Xuece Zhang, Ting Wu, Xu Pan, Zhi Wang
Article Number: 155
Published online on: 22 December 2020

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Article Open Access

MicroRNA‑223‑induced inhibition of the FBXW7 gene affects the proliferation and apoptosis of colorectal cancer cells via the Notch and Akt/mTOR pathways

Zhixin Liu, Teng Ma, Jufeng Duan, Xiaofei Liu, Long Liu
Article Number: 154
Published online on: 20 December 2020

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Article Open Access

lncRNA LIFR‑AS1 inhibits gastric carcinoma cell proliferation, migration and invasion by sponging miR‑4698

Jiangqiao Zhao, Xiaoning Li, Liping Fu, Na Zhang, Jiaping Yang, Jianhui Cai
Article Number: 153
Published online on: 20 December 2020

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Article Open Access

PMCA4 gene expression is regulated by the androgen receptor in the mouse testis during spermatogenesis

Rui Sun, Hui Liang, Huan Guo, Zhu Wang, Qiong Deng
Article Number: 152
Published online on: 20 December 2020

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Article Open Access

Matrix metalloproteinase 3 regulates angiotensin II‑induced myocardial fibrosis cell viability, migration and apoptosis

Jin Shu, Yiwen Gu, Li Jin, Haiya Wang
Article Number: 151
Published online on: 20 December 2020

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Article Open Access

JNK‑IN‑8 treatment alleviates lipopolysaccharide‑induced acute lung injury via suppression of inflammation and oxidative stress regulated by JNK/NF‑κB signaling

Jingxian Du, Gaojian Wang, Huanyu Luo, Na Liu, Junran Xie
Article Number: 150
Published online on: 20 December 2020

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Article Open Access

PRDM14 mediates chemosensitivity and glycolysis in drug‑resistant A549/cisplatin cells and their progenitor A549 human lung adenocarcinoma cells

Saifei He, Xiaokun Ma, Ni Zheng, Guoyu Wang, Menghan Wang, Wei Xia, Donghai Yu
Article Number: 149
Published online on: 17 December 2020

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Article Open Access

OxLDL/β2GPI/anti‑β2GPI Ab complex induces inflammatory activation via the TLR4/NF‑κB pathway in HUVECs

Guiting Zhang, Qianqian Cai, Hong Zhou, Chao He, Yudan Chen, Peng Zhang, Ting Wang, Liangjie Xu, Jinchuan Yan
Article Number: 148
Published online on: 17 December 2020

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Article Open Access

Liraglutide protects palmitate-induced INS-1 cell injury by enhancing autophagy mediated via FoxO1

Xiu-Dan Li, Shan-Shan He, Ting-Ting Wan, Yan-Bo Li
Article Number: 147
Published online on: 17 December 2020

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Article Open Access

Knockdown of long non‑coding RNA ANRIL inhibits the proliferation and promotes the apoptosis of Burkitt lymphoma cells through the TGF‑β1 signaling pathway

Shudan Mao, Jieping Jin, Zhe Li, Wenqi Yang
Article Number: 146
Published online on: 15 December 2020

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Article Open Access

Knockdown of lncRNA ANRIL suppresses the production of inflammatory cytokines and mucin 5AC in nasal epithelial cells via the miR-15a-5p/JAK2 axis

Huo-Wang Liu, Zhong-Liang Hu, Hao Li, Qi-Feng Tan, Jing Tong, Yong-Quan Zhang
Article Number: 145
Published online on: 15 December 2020

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Article Open Access

Atezolizumab alleviates the immunosuppression induced by PD‑L1‑positive neutrophils and improves the survival of mice during sepsis

Jianxin Chen, Ruiyuan Chen, Shaoxiong Huang, Bin Zu, Sen Zhang
Article Number: 144
Published online on: 15 December 2020

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Correction Open Access

[Corrigendum] Vorinostat protects against calcium oxalate‑induced kidney injury in mice

Li Wang, Wei Chen, Zhongjiang Peng, Changcheng Liu, Caihong Zhang, Zhiyong Guo
Article Number: 143
Published online on: 14 December 2020

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Article

Bioinformatics analysis indicates that microRNA‑628‑5p overexpression may alleviate Alzheimer's disease by targeting TYROBP

Miao Liu, Shuling Li, Chun Ma, Xinna Wang, Yu Shuang, Haining Lin, Zhiying Guan, Lihua Yang
Article Number: 142
Published online on: 13 December 2020

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Article Open Access

circARRDC3 contributes to interleukin‑13‑induced inflammatory cytokine and mucus production in nasal epithelial cells via the miR‑375/KLF4 axis

Tao Wang, Peihua Wang, Dong Chen, Zhou Xu, Liyun Yang
Article Number: 141
Published online on: 13 December 2020

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Article Open Access

Sericin inhibits MDA‑MB‑468 cell proliferation via the PI3K/Akt pathway in triple‑negative breast cancer

Lin Niu, Songhe Yang, Xueying Zhao, Xiaochao Liu, Lina Si, Meng Wei, Lei Liu, Luyang Cheng, Yuebing Qiao, Zhihong Chen
Article Number: 140
Published online on: 13 December 2020

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Article Open Access

lncRNA FLVCR1‑AS1 drives colorectal cancer progression via modulation of the miR‑381/RAP2A axis Expression of Concern in /10.3892/mmr.2025.13774

Yi Han, Xiaoyan Wang, Enqiang Mao, Boyong Shen, Liang Huang
Article Number: 139
Published online on: 13 December 2020

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Article Open Access

Inhibition of SNCG suppresses the proliferation of lung cancer cells induced by high glucose

Jing Fei, Chi Xiao, Meiying Yang, Xue Zhou, Ping Gong
Article Number: 138
Published online on: 13 December 2020

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Article Open Access

CBX2 depletion inhibits the proliferation, invasion and migration of gastric cancer cells by inactivating the YAP/β-catenin pathway

Miaomiao Zeng, Bangxue Li, Lei Yang, Quanlin Guan
Article Number: 137
Published online on: 13 December 2020

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Article Open Access

MicroRNA‑338‑3p regulates age‑associated osteoporosis via targeting PCSK5

Jie Tong, Min Zhang, Xia Li, Guohai Ren
Article Number: 136
Published online on: 13 December 2020

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Article Open Access

GAS5 regulates diabetic cardiomyopathy via miR‑221‑3p/p27 axis‑associated autophagy

Dezhi Chen, Min Zhang
Article Number: 135
Published online on: 13 December 2020

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Article Open Access

Upregulation of microRNA‑140‑3p mediates dachshund family transcription factor 1 expression in immunoglobulin A nephropathy through cell cycle‑dependent mechanisms

Xiaobin Zhou, Yao Lu, Pengfei Guo, Chenglin Zhou
Article Number: 134
Published online on: 13 December 2020

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Article

Shikonin ameliorates lipoteichoic acid‑induced acute lung injury via promotion of neutrophil apoptosis

Yong Zhang, Haibo Zhang, Muqun Wang, Shan Gao, Lei Hong, Tingting Hou, Yaoyao Zhang, Yuling Zhu, Feng Qian
Article Number: 133
Published online on: 13 December 2020

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Article Open Access

Analysis of differential expression of long non‑coding RNAs in exosomes derived from mature and immature dendritic cells

Jiachang Wu, Renli Zhao, Jingxing Dai, Guohua Lai, Asmat Ullah Khan, Xiao Yu, Sha Wu, Jun Ouyang, Hongxun Sang
Article Number: 132
Published online on: 10 December 2020

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Article

Long non‑coding RNA H19 inhibition ameliorates oxygen‑glucose deprivation‑induced cell apoptosis and inflammatory cytokine expression by regulating the microRNA‑29b/SIRT1/PGC‑1α axis

Jing Xu, Chunyang Wang, Fanjie Meng, Pengjuan Xu
Article Number: 131
Published online on: 10 December 2020

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Article Open Access

miR‑182‑5p contributes to radioresistance in nasopharyngeal carcinoma by regulating BNIP3 expression Corrigendum in /10.3892/mmr.2021.11935

Wei He, Hongyan Jin, Qian Liu, Quanxin Sun
Article Number: 130
Published online on: 10 December 2020

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Article Open Access

Effect of EZH2 on pulmonary artery smooth muscle cell migration in pulmonary hypertension

Ying Wang, Xiao-Xi Huang, Dong Leng, Ji-Feng Li, Yan Liang, Tao Jiang
Article Number: 129
Published online on: 10 December 2020

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Article Open Access

Gli affects the stemness and prognosis of epithelial ovarian cancer via homeobox protein NANOG

Huan Zhao, Na Li, Yicun Pang, Jun Zhao, Xiaohua Wu
Article Number: 128
Published online on: 10 December 2020

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Article Open Access

Anti‑inflammatory effect of salusin‑β knockdown on LPS‑activated alveolar macrophages via NF‑κB inhibition and HO‑1 activation

Sheng Chen, Yunnan Hu, Jiaxin Zhang, Pengyu Zhang
Article Number: 127
Published online on: 08 December 2020

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Article

Analysis of the intestinal IgA response in mice exposed to chronic stress and treated with bovine lactoferrin

Teresita Rocío Cruz‑Ηernández, Daniel Cuauhtémoc Gómez‑Jiménez, Rafael Campos‑Rodríguez, Marycarmen Godínez‑Victoria, Maria Elisa Drago‑Serrano
Article Number: 126
Published online on: 08 December 2020

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Article Open Access

BMP2 induces hMSC osteogenesis and matrix remodeling

Hantao Cai, Ji Zou, Wei Wang, Aofei Yang
Article Number: 125
Published online on: 08 December 2020

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Article Open Access

miR‑654‑3p suppresses cell viability and promotes apoptosis by targeting RASAL2 in non‑small‑cell lung cancer

Jie Xiong, Shigang Xing, Zheng Dong, Lei Niu, Qinghua Xu, Yusheng Li, Pingyi Liu, Peixia Yang
Article Number: 124
Published online on: 08 December 2020

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Article

Identification of galectin‑10 as a biomarker for periodontitis based on proteomic analysis of gingival crevicular fluid

Jun Su Kim, Il-Hoon Cho, Kyung-Hee Kim, Young Sun Hwang
Article Number: 123
Published online on: 07 December 2020

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Article Open Access

Dickkopf‑1/cysteine‑rich angiogenic inducer 61 axis mediates palmitic acid‑induced inflammation and apoptosis of vascular endothelial cells

Yi-Rong Gan, Ling Wei, Yan-Zhen Wang, Zong-Ke Kou, Tian-Xiang Liang, Guan-Waner Ding, Yan-Hong Ding, Ding-Xiong Xie
Article Number: 122
Published online on: 07 December 2020

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Article Open Access

Induction of mesenchymal stem cell‑like transformation in rat primary glial cells using hypoxia, mild hypothermia and growth factors

Huiping Wei, Wenyun Zhou, Guozhu Hu, Chunhua Shi
Article Number: 121
Published online on: 07 December 2020

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Article Open Access

miR‑34c‑5p targets Notch1 and suppresses the metastasis and invasion of cervical cancer

Huali Wei, Xiaolan Wang, Xiumin Niu, Ruili Jiao, Xiaojuan Li, Sumei Wang
Article Number: 120
Published online on: 07 December 2020

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Retraction Open Access

[Retracted] MicroRNA‑21 increases cell viability and suppresses cellular apoptosis in non‑small cell lung cancer by regulating the PI3K/Akt signaling pathway

Tao Wang, Zhenyu Cai, Guolin Hong, Gangsen Zheng, Yu Huang, Shun Zhang, Jinhua Dai
Article Number: 119
Published online on: 04 December 2020

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Article Open Access

Effects of inhibiting PDK‑1 expression in bone marrow mesenchymal stem cells on osteoblast differentiation in vitro

Yiguang Bai, Qiong Zhang, Quan Zhou, Yanan Zhang, Haibin Nong, Mingfu Liu, Zhuohua Shi, Gaofeng Zeng, Shaohui Zong
Article Number: 118
Published online on: 04 December 2020

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Article Open Access

lncRNA SNHG16 promotes the occurrence of osteoarthritis by sponging miR‑373‑3p

Haiyan Fan, Liangjia Ding, Yun Yang
Article Number: 117
Published online on: 04 December 2020

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Article Open Access

Overexpression of lncRNA Dancr inhibits apoptosis and enhances autophagy to protect cardiomyocytes from endoplasmic reticulum stress injury via sponging microRNA-6324

Jiong Li, Jing Xie, Yan-Zhen Wang, Yi-Rong Gan, Ling Wei, Guan-Waner Ding, Yan-Hong Ding, Ding-Xiong Xie
Article Number: 116
Published online on: 03 December 2020

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Article

WWOX promotes apoptosis and inhibits autophagy in paclitaxel‑treated ovarian carcinoma cells

Yan Zhao, Wen Wang, Wenying Pan, Yunhai Yu, Wenqian Huang, Jiangang Gao, Ying Zhang, Shiqian Zhang
Article Number: 115
Published online on: 03 December 2020

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Correction Open Access

[Erratum] Oxidative stress, autophagy and pyroptosis in the neovascularization of oxygen‑induced retinopathy in mice

Shuai Wang, Li-Yang Ji, Li Li, Jing-Min Li
Article Number: 114
Published online on: 03 December 2020

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Article Open Access

The mRNA expression of Il6 and Pdcd1 are predictive and protective factors for doxorubicin‑induced cardiotoxicity

Syu-Ichi Kanno, Akiyoshi Hara
Article Number: 113
Published online on: 03 December 2020

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Article Open Access

Long non‑coding RNA ANRIL is a potential indicator of disease progression and poor prognosis in acute myeloid leukemia

Zhenqing Tan, Kaibo Zhu, Yafei Yin, Zimian Luo
Article Number: 112
Published online on: 03 December 2020

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Article Open Access

NORAD regulates epithelial‑mesenchymal transition of non‑small cell lung cancer cells via miR‑422a Corrigendum in /10.3892/mmr.2021.12178

Zhikun Chen, Qin Che, Chunxue Xie
Article Number: 111
Published online on: 03 December 2020

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Article Open Access

Prostaglandin E1 attenuates post‑cardiac arrest myocardial dysfunction through inhibition of mitochondria‑mediated cardiomyocyte apoptosis

Chenglei Su, Xinhui Fan, Feng Xu, Jiali Wang, Yuguo Chen
Article Number: 110
Published online on: 02 December 2020

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Article Open Access

hCINAP serves a critical role in hypoxia‑induced cardiomyocyte apoptosis via modulating lactate production and mitochondrial‑mediated apoptosis signaling

Hebing Xie, Gang Xu, Yuqi Gao, Zhibin Yuan
Article Number: 109
Published online on: 02 December 2020

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Article Open Access

Neuroprotective effect of emodin against Alzheimer's disease via Nrf2 signaling in U251 cells and APP/PS1 mice Corrigendum in /10.3892/mmr.2023.12994

Zhiping Li, Hui Bi, Hongbo Jiang, Jingjing Song, Qingfan Meng, Yizhi Zhang, Xiaofang Fei
Article Number: 108
Published online on: 02 December 2020

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Article Open Access

Intermedin protects thapsigargin‑induced endoplasmic reticulum stress in cardiomyocytes by modulating protein kinase A and sarco/endoplasmic reticulum Ca2+‑ATPase

Zhidong Li, Jia Guo, Yunfei Bian, Mingsheng Zhang
Article Number: 107
Published online on: 01 December 2020

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Article Open Access

Molecular mechanism underlying miR‑130b‑Sp1 transcriptional regulation in LPS‑induced upregulation of MUC5AC in the bile duct epithelium

Xiaodong Wu, Chenhui Yao, Jing Kong, Yu Tian, Ying  Fan, Zhen Zhang, Jinyan Han, Shuodong Wu
Article Number: 106
Published online on: 01 December 2020

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Review Open Access

Wnt/β‑catenin signaling: Causes and treatment targets of drug resistance in colorectal cancer (Review)

Gui-Xian Zhu, Dian Gao, Zhao-Zhao Shao, Li Chen, Wen-Jie Ding, Qiong-Fang Yu
Article Number: 105
Published online on: 01 December 2020

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Article Open Access

miR‑139‑5p enhances cisplatin sensitivity in non‑small cell lung cancer cells by inhibiting cell proliferation and promoting apoptosis via the targeting of Homeobox protein Hox‑B2

Hailian Du, Ya'nan Bao, Chunying Liu, Anqiao Zhong, Yikai Niu, Xingping Tang
Article Number: 104
Published online on: 01 December 2020

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Article

YY1 promotes SOCS3 expression to inhibit STAT3‑mediated neuroinflammation and neuropathic pain

Manyi Sun, Yue Sun, Jinfeng Ma, Kezhong Li
Article Number: 103
Published online on: 01 December 2020

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Article Open Access

miR‑125/CDK2 axis in cochlear progenitor cell proliferation

Tao Peng, Jing-Jing Peng, Gang-Yong Miao, Zhi-Qiang Tan, Bin Liu, En Zhou
Article Number: 102
Published online on: 01 December 2020

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Article

Inflammasome components and ADAMTS4 in premature rupture of membranes

Jinming Zhu, Chunling Ma, Xiaomei Luan, Juan Li, Fengyun Peng, Lei Huang
Article Number: 101
Published online on: 01 December 2020

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Penehyclidine hydrochloride alleviates lipopolysaccharide‑induced acute respiratory distress syndrome in cells via regulating autophagy‑related pathway

Xiaopeng Wang, Fen Liu, Min Xu, Liangxia Wu
Article Number: 100
Published online on: 01 December 2020

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Human galectin‑3: Molecular switch of gene expression in dermal fibroblasts in vitro and of skin collagen organization in open wounds and tensile strength in incisions in vivo

Peter Gál, Tomáš Vasilenko, Ivan Kováč, Matúš Čoma, Ján Jakubčo, Martina Jakubčová, Vlasta Peržeľová, Lukáš Urban, Michal Kolář, František Sabol, Ján Luczy, Martin Novotný, Jaroslav Majerník, Hans-Joachim Gabius, Karel Jr Smetana
Article Number: 99
Published online on: 27 November 2020

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Long non‑coding RNA ZFPM2‑AS1 promotes colorectal cancer progression by sponging miR‑137 to regulate TRIM24

Meihua Xiao, Zhi Liang, Zhihui Yin
Article Number: 98
Published online on: 27 November 2020

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Relationship between the pyroptosis of fibroblast‑like synoviocytes and HMGB1 secretion in knee osteoarthritis

Yancheng Xiao, Liang Ding, Songjiang Yin, Zhengquan Huang, Li  Zhang, Wei Mei, Peng Wu, Peimin Wang, Ke Pan
Article Number: 97
Published online on: 27 November 2020

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Review Open Access

Roles of telomeres and telomerase in age‑related renal diseases (Review)

Haili Li, Boyuan Wang, Daoqun Li, Jinyuan Li, Ying Luo, Juhua Dan
Article Number: 96
Published online on: 27 November 2020

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let7f‑5p attenuates inflammatory injury in in vitro pneumonia models by targeting MAPK6

Lin Xu, Qingying Song, Zhanghong Ouyang, Xiangyan Zhang, Cheng Zhang
Article Number: 95
Published online on: 25 November 2020

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miR‑576‑5p promotes epithelial‑to‑mesenchymal transition in colorectal cancer by targeting the Wnt5a‑mediated Wnt/β‑catenin signaling pathway

Jialin Luo, Luying Liu, Jinwen Shen, Ning Zhou, Yanru Feng, Na Zhang, Quanquan Sun, Yuan Zhu
Article Number: 94
Published online on: 25 November 2020

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Article

Nasopharyngeal carcinoma‑associated gene 6 inhibits cell viability, migration, invasion and induces apoptosis in osteosarcoma cells by inactivating the Wnt/β‑catenin signaling pathway

Lun Liu, Ruijing Wang, Zian Zhang, Xiangda Wang
Article Number: 93
Published online on: 25 November 2020

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Development and characterization of TrMab‑6, a novel anti‑TROP2 monoclonal antibody for antigen detection in breast cancer

Yusuke Sayama, Mika K. Kaneko, Yukinari Kato
Article Number: 92
Published online on: 25 November 2020

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FOXK1 plays an oncogenic role in the progression of hilar cholangiocarcinoma

Yujie Feng, Zhigang Bai, Jianning Song, Zhongtao Zhang
Article Number: 91
Published online on: 25 November 2020

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Article

Long non‑coding RNA SNHG14 affects the proliferation and apoptosis of childhood acute myeloid leukaemia cells by modulating the miR‑193b‑3p/MCL1 axis

Xiaoliang Wang, Wenrong Li, Yanhong Chen, Lijuan Zhou
Article Number: 90
Published online on: 25 November 2020

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Journal Cover
March-2026 Volume 33 Issue 3

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article

CTRP4 ameliorates dexamethasone‑induced insulin resistance through the IRS‑1/PI3K/AKT pathway in 3T3‑L1 adipocytes

Maireyanmu Rouzi, Xi Sun, Luguang Sheng, Bilin Xu, Tao Lei, Jun Lu, Jie Gao
Article Number: 101
Published online on: 27 January 2026

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PTUPB, a soluble epoxide hydrolase/cyclooxygenase‑2 dual inhibitor, reduces endothelial‑to‑mesenchymal transition and improves doxorubicin‑induced vascular and cardiac toxicity

Hevna Dhulkifle, Lubna Therachiyil, Maram H. Hasan, Shahd M. Younis, Nizar A. Al‑Shar'i, Huseyin C. Yalcin, Zaid H. Maayah
Article Number: 100
Published online on: 27 January 2026

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Retraction Open Access

[Retracted] miR‑367 enhances the proliferation and invasion of cutaneous malignant melanoma by regulating phosphatase and tensin homolog expression

Jianwen Long, Jing Luo, Xuwen Yin
Article Number: 99
Published online on: 26 January 2026

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Advances in the mechanisms of the NLRP3 inflammasome in sepsis‑induced cardiomyopathy and targeted therapeutic studies 
(Review)

Yifei Chen, Zhaohui Zhang, Gaosheng Zhou
Article Number: 98
Published online on: 22 January 2026

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HMGN2 induces pyroptosis in tumour cells by modulating the STT3B/PD‑L1/caspase‑1/GSDMD axis

Wenwen Han, Hongli Chen, Bomiao Cui, Jiao Chen, Ping Zhang, Yun Feng
Article Number: 97
Published online on: 22 January 2026

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Naringin ameliorates intestinal injury in ulcerative colitis model mice by modulating the JAK2/STAT3 signaling pathway

Miaomiao Wu, Yating An, Yongmin Li, Wei He, Ying Wang, Yaqi Wang, Caixia Wu
Article Number: 96
Published online on: 22 January 2026

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Review

PDX1 in human cancers: Molecular mechanisms, dual roles and clinical implications (Review)

Chen Zhou, Yifei Wang, Jie Zhao, Yantao Yang, Yuhang Yuan, Xiaochen Hou, Yu Tang, Lianhua Ye
Article Number: 95
Published online on: 22 January 2026

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Retraction Open Access

[Retracted] Autophagy flux inhibition mediated by celastrol sensitized lung cancer cells to TRAIL‑induced apoptosis via regulation of mitochondrial transmembrane potential and reactive oxygen species

Uddin Md Nazim, Honghua Yin, Sang-Youel Park
Article Number: 94
Published online on: 19 January 2026

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Converting ‘cold’ to ‘hot’ hepatocellular carcinoma for improved immunotherapy (Review)

Ching-Hua Hsieh, Pei-Chin Chuang
Article Number: 93
Published online on: 15 January 2026

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Pathological mechanism of ferroptosis in a rat model of α‑naphthyl isothiocyanate‑induced chronic cholestasis

Zhen Guo, Jiaxuan Wang, Yiwen Wang, Xinzhu Liu, Yubing Xia, Ping Liu, Li Qi, Jia Liu, Xiaoning Wang
Article Number: 92
Published online on: 14 January 2026

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Correction Open Access

[Corrigendum] Role of hypoxia‑inducible factor‑1α and CD146 in epidermal growth factor receptor‑mediated angiogenesis in salivary gland adenoid cystic carcinom

Wei-Ming Wang, Zhi-Li Zhao, Wen-Feng Zhang, Yi-Fang Zhao, Lu Zhang, Zhi-Jun Sun
Article Number: 91
Published online on: 13 January 2026

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Klebsiella pneumoniae and pyogenic liver abscess: Emerging clinical threats, virulence mechanisms and therapeutic strategies (Review)

Gulam Mustafa Hasan, Taj Mohammad, Sobia Zaidi, Anas Shamsi, Sukhwinder Singh Sohal, Md. Imtaiyaz Hassan
Article Number: 90
Published online on: 13 January 2026

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Collagen III regulates the termination of liver regeneration by suppressing hepatocyte proliferation and promoting functional recovery

Haiyang Peng, Zhiyong Chen, Qiwei Zhang, Yuezhou Zhang, Peng Yang, Jianping Gong, Andong Zhao
Article Number: 89
Published online on: 13 January 2026

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Review Open Access

Application of extracellular vesicles in the diagnosis and treatment of chronic obstructive pulmonary disease (Review)

Yixin Zhang, Tong Ren, Jianbo Xue, Yan Yu, Xianqiang Zhou, Xiaoyi Hu, Wenyi Yu, Zhancheng Gao, Cuiling Feng
Article Number: 88
Published online on: 13 January 2026

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Cigarette smoke combined with Klebsiella pneumoniae induce damage to the air‑blood barrier in chronic obstructive pulmonary disease rats via the MAPK/NF‑κB/IκBα pathway

Yange Tian, Kexin Xu, Ruilong Lu, Kangchen Li, Xuejie Shao, Yixi Liao, Yakun Zhao, Zhiguang Qiu, Haoran Dong, Xuefang Liu
Article Number: 87
Published online on: 12 January 2026

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Retraction Open Access

[Retracted] 8‑bromo‑7‑methoxychrysin induces apoptosis by regulating Akt/FOXO3a pathway in cisplatin‑sensitive and resistant ovarian cancer cells

Qing Ding, Yi Chen, Qing Zhang, Yanling Guo, Zhi Huang, Liqing Dai, Sudan Cao
Article Number: 86
Published online on: 12 January 2026

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Article Open Access

Anxiety‑induced overactive bladder: The role of oxidative stress and NF‑κB signaling pathway with Hsp90 as a potential biomarker

Zhipeng Zhou, Lina Xu, Han Wu, Huaishan Hong
Article Number: 85
Published online on: 12 January 2026

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Echinacoside alleviates asthenozoospermia by upregulating Sox5‑mediated transcriptional activation of the CatSper gene

Zi-Run Jin, Yong-Wei Huo, Bo-Heng Liu, Hong Tian, Shuo Yuan, Yue Tian, Ke Xi, Jie Cai, Hui Jiang, Yong Jiang, Guo-Gang Xing
Article Number: 84
Published online on: 12 January 2026

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Artemisiae Scopariae Herba (Yinchen) suppresses ferroptosis in mice with osteoporosis via the Nrf2/Slc7a11/Gpx4 pathway

Pei Li, Xinyu Wan, Wenjie Li, Ding Cheng, Ying Yang, Yuhan Wang, Ruyuan Zhu, Yanjing Chen, Haixia Liu, Zhiguo Zhang
Article Number: 83
Published online on: 12 January 2026

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Review Open Access

Prolyl hydroxylase domain proteins: Localization, regulation, function and their role in erythropoiesis (Review)

Yan Hou, Zhao-Hua Zhang, Wen-Qian Li, Guo-Xiong Han, Kuo Shen, You-Bang Xie
Article Number: 82
Published online on: 12 January 2026

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Therapeutic potential of saponins for allergic rhinitis: Molecular mechanisms and clinical perspectives (Review)

Bing-Yu Liang, Zi-Yue Fu, Fen-Fen Li, Ping-Ting Zhou, Zi-Hui Xie, Ke Han, Yan-Xun Han, Shan-Wen Chen, Yi Zhao, Hai-Feng Pan, Ye-Hai Liu, Yu-Chen Liu
Article Number: 81
Published online on: 07 January 2026

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Interleukin‑6 and ischemic stroke: From mechanisms to clinical prospects (Review)

Xinyue Wang, Xiaohang Zhang, Jianing Lin, Ping Lin
Article Number: 80
Published online on: 05 January 2026

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Article Open Access

Preliminary exploration of the putative function of SF3A2 in clear cell renal cell carcinoma

Ru Chen, Jie Xu
Article Number: 79
Published online on: 05 January 2026

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Retraction Open Access

[Retracted] TIPE‑2 suppresses growth and aggressiveness of hepatocellular carcinoma cells through downregulation of the phosphoinositide 3‑kinase/AKT signaling pathway

Lin Wang, Chen Chen, Shuzhi Feng, Jianli Tian
Article Number: 78
Published online on: 05 January 2026

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Journal Cover
April-2026 Volume 33 Issue 4

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

Integrative bioinformatics and experimental analysis reveals FRA1 as a key mediator of tubulointerstitial inflammation in lupus nephritis

Wenpeng Ni, Jialin He, Zhouyu Zeng, Jialong Ke, Runpei Lin, Jianming Peng, Kunyi Deng, Lijuan Wen, Yanhui Chen, Chilun Zhang, Yanfen Li, Guanghong Gu
Article Number: 103
Published online on: 28 January 2026

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Correction Open Access

[Corrigendum] Resveratrol improves neurological outcome and neuroinflammation following spinal cord injury through enhancing autophagy involving the AMPK/mTOR pathway

Hong-Yu Meng, De-Cheng Shao, Han Li, Xiao-Dan Huang, Guang Yang, Bing Xu, Hai-Yun Niu
Article Number: 102
Published online on: 28 January 2026

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