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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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February-2021 Volume 23 Issue 2

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Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

Co‑expression of tissue kallikrein 1 and tissue inhibitor of matrix metalloproteinase 1 improves myocardial ischemia‑reperfusion injury by promoting angiogenesis and inhibiting oxidative stress

Shujie Huang, Meixian Chen, Huizhen Yu, Kaiyang Lin, Yansong Guo, Pengli Zhu
Article Number: 166
Published online on: 22 December 2020

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Article Open Access

miR‑126 overexpression attenuates oxygen‑glucose deprivation/reperfusion injury by inhibiting oxidative stress and inflammatory response via the activation of SIRT1/Nrf2 signaling pathway in human umbilical vein endothelial cells Corrigendum in /10.3892/mmr.2021.12158

Jixin Li, Caili Yang, Yan Wang
Article Number: 165
Published online on: 22 December 2020

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Article Open Access

S100A16 suppresses the proliferation, migration and invasion of colorectal cancer cells in part via the JNK/p38 MAPK pathway

Shiyu Ou, Yan Liao, Jie Shi, Jing Tang, Yanqing Ye, Fengfei Wu, Weidong Wang, Jieying Fei, Fang Xie, Lan Bai
Article Number: 164
Published online on: 22 December 2020

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Article

Effects of KAI gene expression on ferroptosis in pancreatic cancer cells

Xu Liu, Xiaozhong Guo, Hongyu Li, Jiang Chen, Hao Han
Article Number: 163
Published online on: 22 December 2020

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Article Open Access

Induction of notochordal differentiation of bone marrow mesenchymal‑derived stem cells via the stimulation of notochordal cell‑rich nucleus pulposus tissue

Defang Li, Qingmin Zeng, Zengxin Jiang, Lei Ding, Wei Lu, Mengxuan Bian, Jingping Wu
Article Number: 162
Published online on: 22 December 2020

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Article Open Access

Mitochondrial proteomics alterations in rat hearts following ischemia/reperfusion and diazoxide post‑conditioning

Yunchao Pan, Yuan Wang, Wenyan Shi, Yun Liu, Song Cao, Tian Yu
Article Number: 161
Published online on: 22 December 2020

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Article Open Access

Age affects the paracrine activity and differentiation potential of human adipose‑derived stem cells

Jeong Seop Park, Gabee Park, Hyun Sook Hong
Article Number: 160
Published online on: 22 December 2020

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Review

Role of peroxisome proliferator-activated receptors in osteoarthritis (Review)

Gang Huang, Wei Jiang, Weiyong Xie, Wei Lu, Weimin Zhu, Zhenhan Deng
Article Number: 159
Published online on: 22 December 2020

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Article

Neochlorogenic acid enhances the antitumor effects of pingyangmycin via regulating TOP2A

Jianhuan Che, Tongxia Zhao, Wen Liu, Shi Chen, Guangyu Yang, Xinyan Li, Dongling Liu
Article Number: 158
Published online on: 22 December 2020

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Article Open Access

Luteolin attenuates angiotensin II‑induced renal damage in apolipoprotein E‑deficient mice

Ying-Shu Liu, Qin Yang, Shen Li, Lan Luo, Hong-Yang Liu, Xin-Yu Li, Zheng-Nan Gao
Article Number: 157
Published online on: 22 December 2020

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Review

Estrogen receptor-associated receptor α and peroxisome proliferator-activated receptor γ in metabolism and disease (Review)

Wei-Yi Huang, Peng-Ming Sun
Article Number: 156
Published online on: 22 December 2020

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Article Open Access

Isoflurane reduces septic neuron injury by HO‑1‑mediated abatement of inflammation and apoptosis

Lina Zhang, Xuece Zhang, Ting Wu, Xu Pan, Zhi Wang
Article Number: 155
Published online on: 22 December 2020

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Article Open Access

MicroRNA‑223‑induced inhibition of the FBXW7 gene affects the proliferation and apoptosis of colorectal cancer cells via the Notch and Akt/mTOR pathways

Zhixin Liu, Teng Ma, Jufeng Duan, Xiaofei Liu, Long Liu
Article Number: 154
Published online on: 20 December 2020

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Article Open Access

lncRNA LIFR‑AS1 inhibits gastric carcinoma cell proliferation, migration and invasion by sponging miR‑4698

Jiangqiao Zhao, Xiaoning Li, Liping Fu, Na Zhang, Jiaping Yang, Jianhui Cai
Article Number: 153
Published online on: 20 December 2020

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Article Open Access

PMCA4 gene expression is regulated by the androgen receptor in the mouse testis during spermatogenesis

Rui Sun, Hui Liang, Huan Guo, Zhu Wang, Qiong Deng
Article Number: 152
Published online on: 20 December 2020

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Article Open Access

Matrix metalloproteinase 3 regulates angiotensin II‑induced myocardial fibrosis cell viability, migration and apoptosis

Jin Shu, Yiwen Gu, Li Jin, Haiya Wang
Article Number: 151
Published online on: 20 December 2020

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Article Open Access

JNK‑IN‑8 treatment alleviates lipopolysaccharide‑induced acute lung injury via suppression of inflammation and oxidative stress regulated by JNK/NF‑κB signaling

Jingxian Du, Gaojian Wang, Huanyu Luo, Na Liu, Junran Xie
Article Number: 150
Published online on: 20 December 2020

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Article Open Access

PRDM14 mediates chemosensitivity and glycolysis in drug‑resistant A549/cisplatin cells and their progenitor A549 human lung adenocarcinoma cells

Saifei He, Xiaokun Ma, Ni Zheng, Guoyu Wang, Menghan Wang, Wei Xia, Donghai Yu
Article Number: 149
Published online on: 17 December 2020

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Article Open Access

OxLDL/β2GPI/anti‑β2GPI Ab complex induces inflammatory activation via the TLR4/NF‑κB pathway in HUVECs

Guiting Zhang, Qianqian Cai, Hong Zhou, Chao He, Yudan Chen, Peng Zhang, Ting Wang, Liangjie Xu, Jinchuan Yan
Article Number: 148
Published online on: 17 December 2020

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Article Open Access

Liraglutide protects palmitate-induced INS-1 cell injury by enhancing autophagy mediated via FoxO1

Xiu-Dan Li, Shan-Shan He, Ting-Ting Wan, Yan-Bo Li
Article Number: 147
Published online on: 17 December 2020

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Article Open Access

Knockdown of long non‑coding RNA ANRIL inhibits the proliferation and promotes the apoptosis of Burkitt lymphoma cells through the TGF‑β1 signaling pathway

Shudan Mao, Jieping Jin, Zhe Li, Wenqi Yang
Article Number: 146
Published online on: 15 December 2020

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Article Open Access

Knockdown of lncRNA ANRIL suppresses the production of inflammatory cytokines and mucin 5AC in nasal epithelial cells via the miR-15a-5p/JAK2 axis

Huo-Wang Liu, Zhong-Liang Hu, Hao Li, Qi-Feng Tan, Jing Tong, Yong-Quan Zhang
Article Number: 145
Published online on: 15 December 2020

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Article Open Access

Atezolizumab alleviates the immunosuppression induced by PD‑L1‑positive neutrophils and improves the survival of mice during sepsis

Jianxin Chen, Ruiyuan Chen, Shaoxiong Huang, Bin Zu, Sen Zhang
Article Number: 144
Published online on: 15 December 2020

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Correction Open Access

[Corrigendum] Vorinostat protects against calcium oxalate‑induced kidney injury in mice

Li Wang, Wei Chen, Zhongjiang Peng, Changcheng Liu, Caihong Zhang, Zhiyong Guo
Article Number: 143
Published online on: 14 December 2020

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Article

Bioinformatics analysis indicates that microRNA‑628‑5p overexpression may alleviate Alzheimer's disease by targeting TYROBP

Miao Liu, Shuling Li, Chun Ma, Xinna Wang, Yu Shuang, Haining Lin, Zhiying Guan, Lihua Yang
Article Number: 142
Published online on: 13 December 2020

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Article Open Access

circARRDC3 contributes to interleukin‑13‑induced inflammatory cytokine and mucus production in nasal epithelial cells via the miR‑375/KLF4 axis

Tao Wang, Peihua Wang, Dong Chen, Zhou Xu, Liyun Yang
Article Number: 141
Published online on: 13 December 2020

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Article Open Access

Sericin inhibits MDA‑MB‑468 cell proliferation via the PI3K/Akt pathway in triple‑negative breast cancer

Lin Niu, Songhe Yang, Xueying Zhao, Xiaochao Liu, Lina Si, Meng Wei, Lei Liu, Luyang Cheng, Yuebing Qiao, Zhihong Chen
Article Number: 140
Published online on: 13 December 2020

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Article Open Access

lncRNA FLVCR1‑AS1 drives colorectal cancer progression via modulation of the miR‑381/RAP2A axis Expression of Concern in /10.3892/mmr.2025.13774

Yi Han, Xiaoyan Wang, Enqiang Mao, Boyong Shen, Liang Huang
Article Number: 139
Published online on: 13 December 2020

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Article Open Access

Inhibition of SNCG suppresses the proliferation of lung cancer cells induced by high glucose

Jing Fei, Chi Xiao, Meiying Yang, Xue Zhou, Ping Gong
Article Number: 138
Published online on: 13 December 2020

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Article Open Access

CBX2 depletion inhibits the proliferation, invasion and migration of gastric cancer cells by inactivating the YAP/β-catenin pathway

Miaomiao Zeng, Bangxue Li, Lei Yang, Quanlin Guan
Article Number: 137
Published online on: 13 December 2020

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Article Open Access

MicroRNA‑338‑3p regulates age‑associated osteoporosis via targeting PCSK5

Jie Tong, Min Zhang, Xia Li, Guohai Ren
Article Number: 136
Published online on: 13 December 2020

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Article Open Access

GAS5 regulates diabetic cardiomyopathy via miR‑221‑3p/p27 axis‑associated autophagy

Dezhi Chen, Min Zhang
Article Number: 135
Published online on: 13 December 2020

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Article Open Access

Upregulation of microRNA‑140‑3p mediates dachshund family transcription factor 1 expression in immunoglobulin A nephropathy through cell cycle‑dependent mechanisms

Xiaobin Zhou, Yao Lu, Pengfei Guo, Chenglin Zhou
Article Number: 134
Published online on: 13 December 2020

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Article

Shikonin ameliorates lipoteichoic acid‑induced acute lung injury via promotion of neutrophil apoptosis

Yong Zhang, Haibo Zhang, Muqun Wang, Shan Gao, Lei Hong, Tingting Hou, Yaoyao Zhang, Yuling Zhu, Feng Qian
Article Number: 133
Published online on: 13 December 2020

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Article Open Access

Analysis of differential expression of long non‑coding RNAs in exosomes derived from mature and immature dendritic cells

Jiachang Wu, Renli Zhao, Jingxing Dai, Guohua Lai, Asmat Ullah Khan, Xiao Yu, Sha Wu, Jun Ouyang, Hongxun Sang
Article Number: 132
Published online on: 10 December 2020

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Article

Long non‑coding RNA H19 inhibition ameliorates oxygen‑glucose deprivation‑induced cell apoptosis and inflammatory cytokine expression by regulating the microRNA‑29b/SIRT1/PGC‑1α axis

Jing Xu, Chunyang Wang, Fanjie Meng, Pengjuan Xu
Article Number: 131
Published online on: 10 December 2020

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Article Open Access

miR‑182‑5p contributes to radioresistance in nasopharyngeal carcinoma by regulating BNIP3 expression Corrigendum in /10.3892/mmr.2021.11935

Wei He, Hongyan Jin, Qian Liu, Quanxin Sun
Article Number: 130
Published online on: 10 December 2020

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Article Open Access

Effect of EZH2 on pulmonary artery smooth muscle cell migration in pulmonary hypertension

Ying Wang, Xiao-Xi Huang, Dong Leng, Ji-Feng Li, Yan Liang, Tao Jiang
Article Number: 129
Published online on: 10 December 2020

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Article Open Access

Gli affects the stemness and prognosis of epithelial ovarian cancer via homeobox protein NANOG

Huan Zhao, Na Li, Yicun Pang, Jun Zhao, Xiaohua Wu
Article Number: 128
Published online on: 10 December 2020

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Article Open Access

Anti‑inflammatory effect of salusin‑β knockdown on LPS‑activated alveolar macrophages via NF‑κB inhibition and HO‑1 activation

Sheng Chen, Yunnan Hu, Jiaxin Zhang, Pengyu Zhang
Article Number: 127
Published online on: 08 December 2020

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Article

Analysis of the intestinal IgA response in mice exposed to chronic stress and treated with bovine lactoferrin

Teresita Rocío Cruz‑Ηernández, Daniel Cuauhtémoc Gómez‑Jiménez, Rafael Campos‑Rodríguez, Marycarmen Godínez‑Victoria, Maria Elisa Drago‑Serrano
Article Number: 126
Published online on: 08 December 2020

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Article Open Access

BMP2 induces hMSC osteogenesis and matrix remodeling

Hantao Cai, Ji Zou, Wei Wang, Aofei Yang
Article Number: 125
Published online on: 08 December 2020

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Article Open Access

miR‑654‑3p suppresses cell viability and promotes apoptosis by targeting RASAL2 in non‑small‑cell lung cancer

Jie Xiong, Shigang Xing, Zheng Dong, Lei Niu, Qinghua Xu, Yusheng Li, Pingyi Liu, Peixia Yang
Article Number: 124
Published online on: 08 December 2020

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Article

Identification of galectin‑10 as a biomarker for periodontitis based on proteomic analysis of gingival crevicular fluid

Jun Su Kim, Il-Hoon Cho, Kyung-Hee Kim, Young Sun Hwang
Article Number: 123
Published online on: 07 December 2020

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Article Open Access

Dickkopf‑1/cysteine‑rich angiogenic inducer 61 axis mediates palmitic acid‑induced inflammation and apoptosis of vascular endothelial cells

Yi-Rong Gan, Ling Wei, Yan-Zhen Wang, Zong-Ke Kou, Tian-Xiang Liang, Guan-Waner Ding, Yan-Hong Ding, Ding-Xiong Xie
Article Number: 122
Published online on: 07 December 2020

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Article Open Access

Induction of mesenchymal stem cell‑like transformation in rat primary glial cells using hypoxia, mild hypothermia and growth factors

Huiping Wei, Wenyun Zhou, Guozhu Hu, Chunhua Shi
Article Number: 121
Published online on: 07 December 2020

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Article Open Access

miR‑34c‑5p targets Notch1 and suppresses the metastasis and invasion of cervical cancer

Huali Wei, Xiaolan Wang, Xiumin Niu, Ruili Jiao, Xiaojuan Li, Sumei Wang
Article Number: 120
Published online on: 07 December 2020

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Retraction Open Access

[Retracted] MicroRNA‑21 increases cell viability and suppresses cellular apoptosis in non‑small cell lung cancer by regulating the PI3K/Akt signaling pathway

Tao Wang, Zhenyu Cai, Guolin Hong, Gangsen Zheng, Yu Huang, Shun Zhang, Jinhua Dai
Article Number: 119
Published online on: 04 December 2020

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Article Open Access

Effects of inhibiting PDK‑1 expression in bone marrow mesenchymal stem cells on osteoblast differentiation in vitro

Yiguang Bai, Qiong Zhang, Quan Zhou, Yanan Zhang, Haibin Nong, Mingfu Liu, Zhuohua Shi, Gaofeng Zeng, Shaohui Zong
Article Number: 118
Published online on: 04 December 2020

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Article Open Access

lncRNA SNHG16 promotes the occurrence of osteoarthritis by sponging miR‑373‑3p

Haiyan Fan, Liangjia Ding, Yun Yang
Article Number: 117
Published online on: 04 December 2020

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Article Open Access

Overexpression of lncRNA Dancr inhibits apoptosis and enhances autophagy to protect cardiomyocytes from endoplasmic reticulum stress injury via sponging microRNA-6324

Jiong Li, Jing Xie, Yan-Zhen Wang, Yi-Rong Gan, Ling Wei, Guan-Waner Ding, Yan-Hong Ding, Ding-Xiong Xie
Article Number: 116
Published online on: 03 December 2020

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Article

WWOX promotes apoptosis and inhibits autophagy in paclitaxel‑treated ovarian carcinoma cells

Yan Zhao, Wen Wang, Wenying Pan, Yunhai Yu, Wenqian Huang, Jiangang Gao, Ying Zhang, Shiqian Zhang
Article Number: 115
Published online on: 03 December 2020

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Correction Open Access

[Erratum] Oxidative stress, autophagy and pyroptosis in the neovascularization of oxygen‑induced retinopathy in mice

Shuai Wang, Li-Yang Ji, Li Li, Jing-Min Li
Article Number: 114
Published online on: 03 December 2020

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Article Open Access

The mRNA expression of Il6 and Pdcd1 are predictive and protective factors for doxorubicin‑induced cardiotoxicity

Syu-Ichi Kanno, Akiyoshi Hara
Article Number: 113
Published online on: 03 December 2020

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Article Open Access

Long non‑coding RNA ANRIL is a potential indicator of disease progression and poor prognosis in acute myeloid leukemia

Zhenqing Tan, Kaibo Zhu, Yafei Yin, Zimian Luo
Article Number: 112
Published online on: 03 December 2020

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Article Open Access

NORAD regulates epithelial‑mesenchymal transition of non‑small cell lung cancer cells via miR‑422a Corrigendum in /10.3892/mmr.2021.12178

Zhikun Chen, Qin Che, Chunxue Xie
Article Number: 111
Published online on: 03 December 2020

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Article Open Access

Prostaglandin E1 attenuates post‑cardiac arrest myocardial dysfunction through inhibition of mitochondria‑mediated cardiomyocyte apoptosis

Chenglei Su, Xinhui Fan, Feng Xu, Jiali Wang, Yuguo Chen
Article Number: 110
Published online on: 02 December 2020

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Article Open Access

hCINAP serves a critical role in hypoxia‑induced cardiomyocyte apoptosis via modulating lactate production and mitochondrial‑mediated apoptosis signaling

Hebing Xie, Gang Xu, Yuqi Gao, Zhibin Yuan
Article Number: 109
Published online on: 02 December 2020

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Article Open Access

Neuroprotective effect of emodin against Alzheimer's disease via Nrf2 signaling in U251 cells and APP/PS1 mice Corrigendum in /10.3892/mmr.2023.12994

Zhiping Li, Hui Bi, Hongbo Jiang, Jingjing Song, Qingfan Meng, Yizhi Zhang, Xiaofang Fei
Article Number: 108
Published online on: 02 December 2020

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Article Open Access

Intermedin protects thapsigargin‑induced endoplasmic reticulum stress in cardiomyocytes by modulating protein kinase A and sarco/endoplasmic reticulum Ca2+‑ATPase

Zhidong Li, Jia Guo, Yunfei Bian, Mingsheng Zhang
Article Number: 107
Published online on: 01 December 2020

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Article Open Access

Molecular mechanism underlying miR‑130b‑Sp1 transcriptional regulation in LPS‑induced upregulation of MUC5AC in the bile duct epithelium

Xiaodong Wu, Chenhui Yao, Jing Kong, Yu Tian, Ying  Fan, Zhen Zhang, Jinyan Han, Shuodong Wu
Article Number: 106
Published online on: 01 December 2020

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Review Open Access

Wnt/β‑catenin signaling: Causes and treatment targets of drug resistance in colorectal cancer (Review)

Gui-Xian Zhu, Dian Gao, Zhao-Zhao Shao, Li Chen, Wen-Jie Ding, Qiong-Fang Yu
Article Number: 105
Published online on: 01 December 2020

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Article Open Access

miR‑139‑5p enhances cisplatin sensitivity in non‑small cell lung cancer cells by inhibiting cell proliferation and promoting apoptosis via the targeting of Homeobox protein Hox‑B2

Hailian Du, Ya'nan Bao, Chunying Liu, Anqiao Zhong, Yikai Niu, Xingping Tang
Article Number: 104
Published online on: 01 December 2020

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Article

YY1 promotes SOCS3 expression to inhibit STAT3‑mediated neuroinflammation and neuropathic pain

Manyi Sun, Yue Sun, Jinfeng Ma, Kezhong Li
Article Number: 103
Published online on: 01 December 2020

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Article Open Access

miR‑125/CDK2 axis in cochlear progenitor cell proliferation

Tao Peng, Jing-Jing Peng, Gang-Yong Miao, Zhi-Qiang Tan, Bin Liu, En Zhou
Article Number: 102
Published online on: 01 December 2020

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Article

Inflammasome components and ADAMTS4 in premature rupture of membranes

Jinming Zhu, Chunling Ma, Xiaomei Luan, Juan Li, Fengyun Peng, Lei Huang
Article Number: 101
Published online on: 01 December 2020

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Penehyclidine hydrochloride alleviates lipopolysaccharide‑induced acute respiratory distress syndrome in cells via regulating autophagy‑related pathway

Xiaopeng Wang, Fen Liu, Min Xu, Liangxia Wu
Article Number: 100
Published online on: 01 December 2020

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Human galectin‑3: Molecular switch of gene expression in dermal fibroblasts in vitro and of skin collagen organization in open wounds and tensile strength in incisions in vivo

Peter Gál, Tomáš Vasilenko, Ivan Kováč, Matúš Čoma, Ján Jakubčo, Martina Jakubčová, Vlasta Peržeľová, Lukáš Urban, Michal Kolář, František Sabol, Ján Luczy, Martin Novotný, Jaroslav Majerník, Hans-Joachim Gabius, Karel Jr Smetana
Article Number: 99
Published online on: 27 November 2020

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Long non‑coding RNA ZFPM2‑AS1 promotes colorectal cancer progression by sponging miR‑137 to regulate TRIM24

Meihua Xiao, Zhi Liang, Zhihui Yin
Article Number: 98
Published online on: 27 November 2020

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Relationship between the pyroptosis of fibroblast‑like synoviocytes and HMGB1 secretion in knee osteoarthritis

Yancheng Xiao, Liang Ding, Songjiang Yin, Zhengquan Huang, Li  Zhang, Wei Mei, Peng Wu, Peimin Wang, Ke Pan
Article Number: 97
Published online on: 27 November 2020

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Review Open Access

Roles of telomeres and telomerase in age‑related renal diseases (Review)

Haili Li, Boyuan Wang, Daoqun Li, Jinyuan Li, Ying Luo, Juhua Dan
Article Number: 96
Published online on: 27 November 2020

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let7f‑5p attenuates inflammatory injury in in vitro pneumonia models by targeting MAPK6

Lin Xu, Qingying Song, Zhanghong Ouyang, Xiangyan Zhang, Cheng Zhang
Article Number: 95
Published online on: 25 November 2020

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miR‑576‑5p promotes epithelial‑to‑mesenchymal transition in colorectal cancer by targeting the Wnt5a‑mediated Wnt/β‑catenin signaling pathway

Jialin Luo, Luying Liu, Jinwen Shen, Ning Zhou, Yanru Feng, Na Zhang, Quanquan Sun, Yuan Zhu
Article Number: 94
Published online on: 25 November 2020

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Nasopharyngeal carcinoma‑associated gene 6 inhibits cell viability, migration, invasion and induces apoptosis in osteosarcoma cells by inactivating the Wnt/β‑catenin signaling pathway

Lun Liu, Ruijing Wang, Zian Zhang, Xiangda Wang
Article Number: 93
Published online on: 25 November 2020

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Development and characterization of TrMab‑6, a novel anti‑TROP2 monoclonal antibody for antigen detection in breast cancer

Yusuke Sayama, Mika K. Kaneko, Yukinari Kato
Article Number: 92
Published online on: 25 November 2020

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FOXK1 plays an oncogenic role in the progression of hilar cholangiocarcinoma

Yujie Feng, Zhigang Bai, Jianning Song, Zhongtao Zhang
Article Number: 91
Published online on: 25 November 2020

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Long non‑coding RNA SNHG14 affects the proliferation and apoptosis of childhood acute myeloid leukaemia cells by modulating the miR‑193b‑3p/MCL1 axis

Xiaoliang Wang, Wenrong Li, Yanhong Chen, Lijuan Zhou
Article Number: 90
Published online on: 25 November 2020

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Journal Cover
February-2026 Volume 33 Issue 2

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

ISX promotes tumor migration and invasion in lung cancer by upregulating COL1A1 in vitro

Yihe Ma, Ye Chen, Yuhui Liang, Yun Huang, Miao Gong, Lifeng Tian, Xiaojun Xiao, Jingyan Liu, Qinmiao Huang
Article Number: 77
Published online on: 31 December 2025

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Role and mechanism of miR‑222‑5p in endothelial cell apoptosis

Shimeng Wang, Boxin Zhao, Ying Cui, Lin Gui, Jingyao Fan, Lijuan Huang
Article Number: 76
Published online on: 31 December 2025

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Expression of Concern Open Access

[Expression of Concern] MicroRNA-29c inhibits proliferation and promotes apoptosis in non-small cell lung cancer cells by targeting VEGFA

Shijuan Zhan, Chunfeng Wang, Fangqing Yin
Article Number: 75
Published online on: 22 December 2025

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Melatonin induces autophagy in neuroblastoma by alleviating Pak2‑mediated endoplasmic reticulum stress

Qian-Qi Qiu, Na Zhang, Ying-Yi Xu, Jing-Wen Qin, Gao-Feng Yu, Xing-Rong Song
Article Number: 74
Published online on: 22 December 2025

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ST3Gal1 modulates intestinal barrier function and impacts human ulcerative colitis

Yin Tian, Yun Liu, Yangyang Shang, Lijian Ran, Li Liu, Rongquan Wang, Jun Ye
Article Number: 73
Published online on: 18 December 2025

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Mechanistic study of miR‑369‑3p in regulating the Wnt/β‑catenin signaling pathway via targeting SPTBN1 in inflammatory response and bone destruction of rheumatoid arthritis

Aihong Wu, Yuan Wang, Feifei Liu, Zhoufang Cao, Shuhui Du, Mengyu Sun
Article Number: 72
Published online on: 18 December 2025

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CACNB1 alleviates mepivacaine‑induced myocardial ischemia/reperfusion injury by promoting Nrf2 nuclear translocation

Qingbo Shao, Ji Zhang, Huaying Wang
Article Number: 71
Published online on: 17 December 2025

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Expression of Concern Open Access

[Expression of Concern] Effects of cullin 4B on the proliferation and invasion of human gastric cancer cells

Feng He, Xiu-Mei Cheng, Wen-Long Gu
Article Number: 70
Published online on: 17 December 2025

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Aggravated effects of human parvovirus B19 NS1 protein on bleomycin‑induced pulmonary fibrosis

Tsai-Ching Hsu, Chih-Chen Tzang, Chia-Wei Kuo, Zhi-Han Wen, Der-Yuan Chen, Bor-Show Tzang
Article Number: 69
Published online on: 16 December 2025

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Advances regarding the mechanism of endoplasmic reticulum stress in diabetic kidney disease and pharmacological interventions (Review)

Pai Zhang, Yabin Cui, Chunyan Liu, Chengji Cui, Shoulin Zhang, Yue Zhang, Fan Li
Article Number: 68
Published online on: 16 December 2025

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Retraction Open Access

[Retracted] N‑Myc downstream‑regulated gene 2 suppresses the proliferation of T24 human bladder cancer cells via induction of oncosis

Jie Huang, Zhou Wu, Guangxiu Wang, Yingxian Cai, Minshan Cai, Yaozhang Li
Article Number: 67
Published online on: 15 December 2025

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Deciphering epigenetic regulation in cardiac developmental toxicity: Mechanisms and implications (Review)

Ziling Qin, Ranran Chen, Dianrong Song
Article Number: 66
Published online on: 11 December 2025

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Gut microbiota as a multifaceted modulator of prostate cancer: Mechanistic insights, therapeutic opportunities and clinical challenges (Review)

Zhenming Hao, Yongqiang Xie, Ru Zhang, Hui Sang, Luxi Li, Yulin Liu, Jinbo Hu, Jijun Wang, Keqiang Chai, Qiang Zhao
Article Number: 65
Published online on: 11 December 2025

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Expression of Concern Open Access

[Expression of Concern] lncRNA FLVCR1‑AS1 drives colorectal cancer progression via modulation of the miR‑381/RAP2A axis

Yi Han, Xiaoyan Wang, Enqiang Mao, Boyong Shen, Liang Huang
Article Number: 64
Published online on: 10 December 2025

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Influence and treatment of insulin receptor substrate/PI3K/Akt‑mediated insulin resistance in diabetes mellitus (Review)

Weikang Tang, Huixia Liu, Xuan Li, Siyao Deng, Changyu Gao
Article Number: 63
Published online on: 09 December 2025

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Retraction Open Access

[Retracted] Long non‑coding RNA ANRIL knockdown suppresses apoptosis and pro‑inflammatory cytokines while enhancing neurite outgrowth via binding microRNA‑125a in a cellular model of Alzheimer’s disease

Bingling Zhou, Lijuan Li, Xin Qiu, Jiashun Wu, Lei Xu, Wei Shao
Article Number: 62
Published online on: 08 December 2025

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Mitophagy and oxidative stress in chronic kidney disease (Review)

Quwu Mushuo, Yihuai Tian, Jianchun Li, Yanqin Qiu, Hui Fan, Qiongdan Hu, Qiong Zhang
Article Number: 61
Published online on: 04 December 2025

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ABCC9 knockdown attenuates isoproterenol‑induced myocardial hypertrophy by inhibiting the PI3K/AKT signaling pathway

Qian Peng, Rui Chang, Linlin Ma, Yanfei Li
Article Number: 60
Published online on: 04 December 2025

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Article

MeCP2 suppresses ferroptosis to drive EMT in retinal pigment epithelial cells: Implications for PVR pathogenesis

Sibei Guo, Yongya Zhang, Xue Li, Xueru Zhao, Yingjuan Liang, Xiaohua Li
Article Number: 59
Published online on: 04 December 2025

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Correction Open Access

[Corrigendum] Screening for implicated genes in colorectal cancer using whole‑genome gene expression profiling

Long-Ci Sun, Hai-Xin Qian
Article Number: 58
Published online on: 04 December 2025

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Article Open Access

Hyperoside prevents osteoporosis by activating the PI3K/AKT signaling pathway to inhibit oxidative stress and promote osteogenesis

Lirong Li, Huaidong Deng, Shabin Zhuan, Boyu Wu, Dawei Xiao
Article Number: 57
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] Interference with Tim‑3 protein expression attenuates the invasion of clear cell renal cell carcinoma and aggravates anoikis

Muming Yu, Bin Lu, Yancun Liu, Ying Me, Lijun Wang, Hui Li
Article Number: 56
Published online on: 01 December 2025

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Acetylshikonin induces ferroptosis via the lipid peroxidation pathway in osteosarcoma cells

Ji-Ying Chen, Guo-Shou Wang, Tsung-Ming Chang, Ju-Fang Liu
Article Number: 55
Published online on: 27 November 2025

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Liver X receptor: A potential target for inflammatory bowel disease and colorectal cancer (Review)

Yingjie Li, Xiaoyan Fu, Meiwen Bai, Jiaqi Zhou, Jiatai Qiu, Hongxia Zhang, Shujuan Liang, Meifang Liu
Article Number: 54
Published online on: 27 November 2025

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lncRNA NEAT1 promotes the proliferation of hemangioma cells by transcriptionally activating β‑catenin via enhancing H3K18 lactylation

Li Yu, Nian Zhou, Xiao-Liang Zhang, Xue-Jing Pang, Lu Xing, Yun-Jing Pu, Li Zhang, Jing-Nan Wu, Hong Shu
Article Number: 53
Published online on: 25 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑206 exerts anti‑oncogenic functions in esophageal squamous cell carcinoma by suppressing the c‑Met/AKT/mTOR pathway

Jin Zhang, Xianen Fa, Qingyong Zhang
Article Number: 52
Published online on: 25 November 2025

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Journal Cover
March-2026 Volume 33 Issue 3

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Interleukin‑6 and ischemic stroke: From mechanisms to clinical prospects (Review)

Xinyue Wang, Xiaohang Zhang, Jianing Lin, Ping Lin
Article Number: 80
Published online on: 05 January 2026

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Preliminary exploration of the putative function of SF3A2 in clear cell renal cell carcinoma

Ru Chen, Jie Xu
Article Number: 79
Published online on: 05 January 2026

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Retraction Open Access

[Retracted] TIPE‑2 suppresses growth and aggressiveness of hepatocellular carcinoma cells through downregulation of the phosphoinositide 3‑kinase/AKT signaling pathway

Lin Wang, Chen Chen, Shuzhi Feng, Jianli Tian
Article Number: 78
Published online on: 05 January 2026

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