Journal Articles

Article Open Access

Co‑expression of tissue kallikrein 1 and tissue inhibitor of matrix metalloproteinase 1 improves myocardial ischemia‑reperfusion injury by promoting angiogenesis and inhibiting oxidative stress

Shujie Huang, Meixian Chen, Huizhen Yu, Kaiyang Lin, Yansong Guo, Pengli Zhu

Article Number: 166 Published online on: 22 December 2020
Article Open Access

S100A16 suppresses the proliferation, migration and invasion of colorectal cancer cells in part via the JNK/p38 MAPK pathway

Shiyu Ou, Yan Liao, Jie Shi, Jing Tang, Yanqing Ye, Fengfei Wu, Weidong Wang, Jieying Fei, Fang Xie, Lan Bai

Article Number: 164 Published online on: 22 December 2020
Article

Effects of KAI gene expression on ferroptosis in pancreatic cancer cells

Xu Liu, Xiaozhong Guo, Hongyu Li, Jiang Chen, Hao Han

Article Number: 163 Published online on: 22 December 2020
Article Open Access

Induction of notochordal differentiation of bone marrow mesenchymal‑derived stem cells via the stimulation of notochordal cell‑rich nucleus pulposus tissue

Defang Li, Qingmin Zeng, Zengxin Jiang, Lei Ding, Wei Lu, Mengxuan Bian, Jingping Wu

Article Number: 162 Published online on: 22 December 2020
Article Open Access

Mitochondrial proteomics alterations in rat hearts following ischemia/reperfusion and diazoxide post‑conditioning

Yunchao Pan, Yuan Wang, Wenyan Shi, Yun Liu, Song Cao, Tian Yu

Article Number: 161 Published online on: 22 December 2020
Article Open Access

Age affects the paracrine activity and differentiation potential of human adipose‑derived stem cells

Jeong Seop Park, Gabee Park, Hyun Sook Hong

Article Number: 160 Published online on: 22 December 2020
Review

Role of peroxisome proliferator-activated receptors in osteoarthritis (Review)

Gang Huang, Wei Jiang, Weiyong Xie, Wei Lu, Weimin Zhu, Zhenhan Deng

Article Number: 159 Published online on: 22 December 2020
Article

Neochlorogenic acid enhances the antitumor effects of pingyangmycin via regulating TOP2A

Jianhuan Che, Tongxia Zhao, Wen Liu, Shi Chen, Guangyu Yang, Xinyan Li, Dongling Liu

Article Number: 158 Published online on: 22 December 2020
Article Open Access

Luteolin attenuates angiotensin II‑induced renal damage in apolipoprotein E‑deficient mice

Ying-Shu Liu, Qin Yang, Shen Li, Lan Luo, Hong-Yang Liu, Xin-Yu Li, Zheng-Nan Gao

Article Number: 157 Published online on: 22 December 2020
Review

Estrogen receptor-associated receptor α and peroxisome proliferator-activated receptor γ in metabolism and disease (Review)

Wei-Yi Huang, Peng-Ming Sun

Article Number: 156 Published online on: 22 December 2020
Article Open Access

Isoflurane reduces septic neuron injury by HO‑1‑mediated abatement of inflammation and apoptosis

Lina Zhang, Xuece Zhang, Ting Wu, Xu Pan, Zhi Wang

Article Number: 155 Published online on: 22 December 2020
Article Open Access

MicroRNA‑223‑induced inhibition of the FBXW7 gene affects the proliferation and apoptosis of colorectal cancer cells via the Notch and Akt/mTOR pathways

Zhixin Liu, Teng Ma, Jufeng Duan, Xiaofei Liu, Long Liu

Article Number: 154 Published online on: 20 December 2020
Article Open Access

lncRNA LIFR‑AS1 inhibits gastric carcinoma cell proliferation, migration and invasion by sponging miR‑4698

Jiangqiao Zhao, Xiaoning Li, Liping Fu, Na Zhang, Jiaping Yang, Jianhui Cai

Article Number: 153 Published online on: 20 December 2020
Article Open Access

PMCA4 gene expression is regulated by the androgen receptor in the mouse testis during spermatogenesis

Rui Sun, Hui Liang, Huan Guo, Zhu Wang, Qiong Deng

Article Number: 152 Published online on: 20 December 2020
Article Open Access

Matrix metalloproteinase 3 regulates angiotensin II‑induced myocardial fibrosis cell viability, migration and apoptosis

Jin Shu, Yiwen Gu, Li Jin, Haiya Wang

Article Number: 151 Published online on: 20 December 2020
Article Open Access

JNK‑IN‑8 treatment alleviates lipopolysaccharide‑induced acute lung injury via suppression of inflammation and oxidative stress regulated by JNK/NF‑κB signaling

Jingxian Du, Gaojian Wang, Huanyu Luo, Na Liu, Junran Xie

Article Number: 150 Published online on: 20 December 2020
Article Open Access

PRDM14 mediates chemosensitivity and glycolysis in drug‑resistant A549/cisplatin cells and their progenitor A549 human lung adenocarcinoma cells

Saifei He, Xiaokun Ma, Ni Zheng, Guoyu Wang, Menghan Wang, Wei Xia, Donghai Yu

Article Number: 149 Published online on: 17 December 2020
Article Open Access

OxLDL/β2GPI/anti‑β2GPI Ab complex induces inflammatory activation via the TLR4/NF‑κB pathway in HUVECs

Guiting Zhang, Qianqian Cai, Hong Zhou, Chao He, Yudan Chen, Peng Zhang, Ting Wang, Liangjie Xu, Jinchuan Yan

Article Number: 148 Published online on: 17 December 2020
Article Open Access

Liraglutide protects palmitate-induced INS-1 cell injury by enhancing autophagy mediated via FoxO1

Xiu-Dan Li, Shan-Shan He, Ting-Ting Wan, Yan-Bo Li

Article Number: 147 Published online on: 17 December 2020
Article Open Access
Article Open Access

Knockdown of lncRNA ANRIL suppresses the production of inflammatory cytokines and mucin 5AC in nasal epithelial cells via the miR-15a-5p/JAK2 axis

Huo-Wang Liu, Zhong-Liang Hu, Hao Li, Qi-Feng Tan, Jing Tong, Yong-Quan Zhang

Article Number: 145 Published online on: 15 December 2020
Article Open Access

Atezolizumab alleviates the immunosuppression induced by PD‑L1‑positive neutrophils and improves the survival of mice during sepsis

Jianxin Chen, Ruiyuan Chen, Shaoxiong Huang, Bin Zu, Sen Zhang

Article Number: 144 Published online on: 15 December 2020
Correction Open Access

[Corrigendum] Vorinostat protects against calcium oxalate‑induced kidney injury in mice

Li Wang, Wei Chen, Zhongjiang Peng, Changcheng Liu, Caihong Zhang, Zhiyong Guo

Article Number: 143 Published online on: 14 December 2020
Article

Bioinformatics analysis indicates that microRNA‑628‑5p overexpression may alleviate Alzheimer's disease by targeting TYROBP

Miao Liu, Shuling Li, Chun Ma, Xinna Wang, Yu Shuang, Haining Lin, Zhiying Guan, Lihua Yang

Article Number: 142 Published online on: 13 December 2020
Article Open Access

circARRDC3 contributes to interleukin‑13‑induced inflammatory cytokine and mucus production in nasal epithelial cells via the miR‑375/KLF4 axis

Tao Wang, Peihua Wang, Dong Chen, Zhou Xu, Liyun Yang

Article Number: 141 Published online on: 13 December 2020
Article Open Access

Sericin inhibits MDA‑MB‑468 cell proliferation via the PI3K/Akt pathway in triple‑negative breast cancer

Lin Niu, Songhe Yang, Xueying Zhao, Xiaochao Liu, Lina Si, Meng Wei, Lei Liu, Luyang Cheng, Yuebing Qiao, Zhihong Chen

Article Number: 140 Published online on: 13 December 2020
Article Open Access

lncRNA FLVCR1‑AS1 drives colorectal cancer progression via modulation of the miR‑381/RAP2A axis

Yi Han, Xiaoyan Wang, Enqiang Mao, Boyong Shen, Liang Huang

Article Number: 139 Published online on: 13 December 2020
Article Open Access

Inhibition of SNCG suppresses the proliferation of lung cancer cells induced by high glucose

Jing Fei, Chi Xiao, Meiying Yang, Xue Zhou, Ping Gong

Article Number: 138 Published online on: 13 December 2020
Article Open Access

CBX2 depletion inhibits the proliferation, invasion and migration of gastric cancer cells by inactivating the YAP/β-catenin pathway

Miaomiao Zeng, Bangxue Li, Lei Yang, Quanlin Guan

Article Number: 137 Published online on: 13 December 2020
Article Open Access

MicroRNA‑338‑3p regulates age‑associated osteoporosis via targeting PCSK5

Jie Tong, Min Zhang, Xia Li, Guohai Ren

Article Number: 136 Published online on: 13 December 2020
Article Open Access

GAS5 regulates diabetic cardiomyopathy via miR‑221‑3p/p27 axis‑associated autophagy

Dezhi Chen, Min Zhang

Article Number: 135 Published online on: 13 December 2020
Article Open Access
Article

Shikonin ameliorates lipoteichoic acid‑induced acute lung injury via promotion of neutrophil apoptosis

Yong Zhang, Haibo Zhang, Muqun Wang, Shan Gao, Lei Hong, Tingting Hou, Yaoyao Zhang, Yuling Zhu, Feng Qian

Article Number: 133 Published online on: 13 December 2020
Article Open Access

Analysis of differential expression of long non‑coding RNAs in exosomes derived from mature and immature dendritic cells

Jiachang Wu, Renli Zhao, Jingxing Dai, Guohua Lai, Asmat Ullah Khan, Xiao Yu, Sha Wu, Jun Ouyang, Hongxun Sang

Article Number: 132 Published online on: 10 December 2020
Article Open Access

miR‑182‑5p contributes to radioresistance in nasopharyngeal carcinoma by regulating BNIP3 expression Corrigendum in /10.3892/mmr.2021.11935

Wei He, Hongyan Jin, Qian Liu, Quanxin Sun

Article Number: 130 Published online on: 10 December 2020
Article Open Access

Effect of EZH2 on pulmonary artery smooth muscle cell migration in pulmonary hypertension

Ying Wang, Xiao-Xi Huang, Dong Leng, Ji-Feng Li, Yan Liang, Tao Jiang

Article Number: 129 Published online on: 10 December 2020
Article Open Access

Gli affects the stemness and prognosis of epithelial ovarian cancer via homeobox protein NANOG

Huan Zhao, Na Li, Yicun Pang, Jun Zhao, Xiaohua Wu

Article Number: 128 Published online on: 10 December 2020
Article Open Access

Anti‑inflammatory effect of salusin‑β knockdown on LPS‑activated alveolar macrophages via NF‑κB inhibition and HO‑1 activation

Sheng Chen, Yunnan Hu, Jiaxin Zhang, Pengyu Zhang

Article Number: 127 Published online on: 08 December 2020
Article

Analysis of the intestinal IgA response in mice exposed to chronic stress and treated with bovine lactoferrin

Teresita Rocío Cruz‑Ηernández, Daniel Cuauhtémoc Gómez‑Jiménez, Rafael Campos‑Rodríguez, Marycarmen Godínez‑Victoria, Maria Elisa Drago‑Serrano

Article Number: 126 Published online on: 08 December 2020
Article Open Access

BMP2 induces hMSC osteogenesis and matrix remodeling

Hantao Cai, Ji Zou, Wei Wang, Aofei Yang

Article Number: 125 Published online on: 08 December 2020
Article Open Access

miR‑654‑3p suppresses cell viability and promotes apoptosis by targeting RASAL2 in non‑small‑cell lung cancer

Jie Xiong, Shigang Xing, Zheng Dong, Lei Niu, Qinghua Xu, Yusheng Li, Pingyi Liu, Peixia Yang

Article Number: 124 Published online on: 08 December 2020
Article

Identification of galectin‑10 as a biomarker for periodontitis based on proteomic analysis of gingival crevicular fluid

Jun Su Kim, Il-Hoon Cho, Kyung-Hee Kim, Young Sun Hwang

Article Number: 123 Published online on: 07 December 2020
Article Open Access

Dickkopf‑1/cysteine‑rich angiogenic inducer 61 axis mediates palmitic acid‑induced inflammation and apoptosis of vascular endothelial cells

Yi-Rong Gan, Ling Wei, Yan-Zhen Wang, Zong-Ke Kou, Tian-Xiang Liang, Guan-Waner Ding, Yan-Hong Ding, Ding-Xiong Xie

Article Number: 122 Published online on: 07 December 2020
Article Open Access

Induction of mesenchymal stem cell‑like transformation in rat primary glial cells using hypoxia, mild hypothermia and growth factors

Huiping Wei, Wenyun Zhou, Guozhu Hu, Chunhua Shi

Article Number: 121 Published online on: 07 December 2020
Article Open Access

miR‑34c‑5p targets Notch1 and suppresses the metastasis and invasion of cervical cancer

Huali Wei, Xiaolan Wang, Xiumin Niu, Ruili Jiao, Xiaojuan Li, Sumei Wang

Article Number: 120 Published online on: 07 December 2020
Retraction Open Access

[Retracted] MicroRNA‑21 increases cell viability and suppresses cellular apoptosis in non‑small cell lung cancer by regulating the PI3K/Akt signaling pathway

Tao Wang, Zhenyu Cai, Guolin Hong, Gangsen Zheng, Yu Huang, Shun Zhang, Jinhua Dai

Article Number: 119 Published online on: 04 December 2020
Article Open Access

Effects of inhibiting PDK‑1 expression in bone marrow mesenchymal stem cells on osteoblast differentiation in vitro

Yiguang Bai, Qiong Zhang, Quan Zhou, Yanan Zhang, Haibin Nong, Mingfu Liu, Zhuohua Shi, Gaofeng Zeng, Shaohui Zong

Article Number: 118 Published online on: 04 December 2020
Article Open Access

lncRNA SNHG16 promotes the occurrence of osteoarthritis by sponging miR‑373‑3p

Haiyan Fan, Liangjia Ding, Yun Yang

Article Number: 117 Published online on: 04 December 2020
Article Open Access

Overexpression of lncRNA Dancr inhibits apoptosis and enhances autophagy to protect cardiomyocytes from endoplasmic reticulum stress injury via sponging microRNA-6324

Jiong Li, Jing Xie, Yan-Zhen Wang, Yi-Rong Gan, Ling Wei, Guan-Waner Ding, Yan-Hong Ding, Ding-Xiong Xie

Article Number: 116 Published online on: 03 December 2020
Article

WWOX promotes apoptosis and inhibits autophagy in paclitaxel‑treated ovarian carcinoma cells

Yan Zhao, Wen Wang, Wenying Pan, Yunhai Yu, Wenqian Huang, Jiangang Gao, Ying Zhang, Shiqian Zhang

Article Number: 115 Published online on: 03 December 2020
Correction Open Access

[Erratum] Oxidative stress, autophagy and pyroptosis in the neovascularization of oxygen‑induced retinopathy in mice

Shuai Wang, Li-Yang Ji, Li Li, Jing-Min Li

Article Number: 114 Published online on: 03 December 2020
Article Open Access

The mRNA expression of Il6 and Pdcd1 are predictive and protective factors for doxorubicin‑induced cardiotoxicity

Syu-Ichi Kanno, Akiyoshi Hara

Article Number: 113 Published online on: 03 December 2020
Article Open Access

Long non‑coding RNA ANRIL is a potential indicator of disease progression and poor prognosis in acute myeloid leukemia

Zhenqing Tan, Kaibo Zhu, Yafei Yin, Zimian Luo

Article Number: 112 Published online on: 03 December 2020
Article Open Access
Article Open Access

Prostaglandin E1 attenuates post‑cardiac arrest myocardial dysfunction through inhibition of mitochondria‑mediated cardiomyocyte apoptosis

Chenglei Su, Xinhui Fan, Feng Xu, Jiali Wang, Yuguo Chen

Article Number: 110 Published online on: 02 December 2020
Article Open Access
Article Open Access

Neuroprotective effect of emodin against Alzheimer's disease via Nrf2 signaling in U251 cells and APP/PS1 mice

Zhiping Li, Hui Bi, Hongbo Jiang, Jingjing Song, Qingfan Meng, Yizhi Zhang, Xiaofang Fei

Article Number: 108 Published online on: 02 December 2020
Article Open Access
Article Open Access

Molecular mechanism underlying miR‑130b‑Sp1 transcriptional regulation in LPS‑induced upregulation of MUC5AC in the bile duct epithelium

Xiaodong Wu, Chenhui Yao, Jing Kong, Yu Tian, Ying  Fan, Zhen Zhang, Jinyan Han, Shuodong Wu

Article Number: 106 Published online on: 01 December 2020
Review Open Access

Wnt/β‑catenin signaling: Causes and treatment targets of drug resistance in colorectal cancer (Review)

Gui-Xian Zhu, Dian Gao, Zhao-Zhao Shao, Li Chen, Wen-Jie Ding, Qiong-Fang Yu

Article Number: 105 Published online on: 01 December 2020
Article Open Access

miR‑139‑5p enhances cisplatin sensitivity in non‑small cell lung cancer cells by inhibiting cell proliferation and promoting apoptosis via the targeting of Homeobox protein Hox‑B2

Hailian Du, Ya'nan Bao, Chunying Liu, Anqiao Zhong, Yikai Niu, Xingping Tang

Article Number: 104 Published online on: 01 December 2020
Article

YY1 promotes SOCS3 expression to inhibit STAT3‑mediated neuroinflammation and neuropathic pain

Manyi Sun, Yue Sun, Jinfeng Ma, Kezhong Li

Article Number: 103 Published online on: 01 December 2020
Article Open Access

miR‑125/CDK2 axis in cochlear progenitor cell proliferation

Tao Peng, Jing-Jing Peng, Gang-Yong Miao, Zhi-Qiang Tan, Bin Liu, En Zhou

Article Number: 102 Published online on: 01 December 2020
Article

Inflammasome components and ADAMTS4 in premature rupture of membranes

Jinming Zhu, Chunling Ma, Xiaomei Luan, Juan Li, Fengyun Peng, Lei Huang

Article Number: 101 Published online on: 01 December 2020
Article Open Access

Penehyclidine hydrochloride alleviates lipopolysaccharide‑induced acute respiratory distress syndrome in cells via regulating autophagy‑related pathway

Xiaopeng Wang, Fen Liu, Min Xu, Liangxia Wu

Article Number: 100 Published online on: 01 December 2020
Article Open Access

Human galectin‑3: Molecular switch of gene expression in dermal fibroblasts in vitro and of skin collagen organization in open wounds and tensile strength in incisions in vivo

Peter Gál, Tomáš Vasilenko, Ivan Kováč, Matúš Čoma, Ján Jakubčo, Martina Jakubčová, Vlasta Peržeľová, Lukáš Urban, Michal Kolář, František Sabol, Ján Luczy, Martin Novotný, Jaroslav Majerník, Hans-Joachim Gabius, Karel Jr Smetana

Article Number: 99 Published online on: 27 November 2020
Article Open Access

Long non‑coding RNA ZFPM2‑AS1 promotes colorectal cancer progression by sponging miR‑137 to regulate TRIM24

Meihua Xiao, Zhi Liang, Zhihui Yin

Article Number: 98 Published online on: 27 November 2020
Article Open Access

Relationship between the pyroptosis of fibroblast‑like synoviocytes and HMGB1 secretion in knee osteoarthritis

Yancheng Xiao, Liang Ding, Songjiang Yin, Zhengquan Huang, Li  Zhang, Wei Mei, Peng Wu, Peimin Wang, Ke Pan

Article Number: 97 Published online on: 27 November 2020
Review Open Access

Roles of telomeres and telomerase in age‑related renal diseases (Review)

Haili Li, Boyuan Wang, Daoqun Li, Jinyuan Li, Ying Luo, Juhua Dan

Article Number: 96 Published online on: 27 November 2020
Article Open Access

let7f‑5p attenuates inflammatory injury in in vitro pneumonia models by targeting MAPK6

Lin Xu, Qingying Song, Zhanghong Ouyang, Xiangyan Zhang, Cheng Zhang

Article Number: 95 Published online on: 25 November 2020
Article Open Access

miR‑576‑5p promotes epithelial‑to‑mesenchymal transition in colorectal cancer by targeting the Wnt5a‑mediated Wnt/β‑catenin signaling pathway

Jialin Luo, Luying Liu, Jinwen Shen, Ning Zhou, Yanru Feng, Na Zhang, Quanquan Sun, Yuan Zhu

Article Number: 94 Published online on: 25 November 2020
Article Open Access

Development and characterization of TrMab‑6, a novel anti‑TROP2 monoclonal antibody for antigen detection in breast cancer

Yusuke Sayama, Mika K. Kaneko, Yukinari Kato

Article Number: 92 Published online on: 25 November 2020
Article Open Access

FOXK1 plays an oncogenic role in the progression of hilar cholangiocarcinoma

Yujie Feng, Zhigang Bai, Jianning Song, Zhongtao Zhang

Article Number: 91 Published online on: 25 November 2020
Article

Long non‑coding RNA SNHG14 affects the proliferation and apoptosis of childhood acute myeloid leukaemia cells by modulating the miR‑193b‑3p/MCL1 axis

Xiaoliang Wang, Wenrong Li, Yanhong Chen, Lijuan Zhou

Article Number: 90 Published online on: 25 November 2020
Journal Cover

February-2021
Volume 23 Issue 2

Print ISSN: 1791-2997
Online ISSN: 1791-3004

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