Open Access

Research progress of the transcription factor Brn4 (Review)

  • Authors:
    • Yuying Wu
    • Xunrui Zhang
    • Jue Wang
    • Guohua Jin
    • Xinhua Zhang
  • View Affiliations

  • Published online on: December 31, 2020     https://doi.org/10.3892/mmr.2020.11818
  • Article Number: 179
  • Copyright: © Wu et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )


Abstract

Brain 4 (Brn4) is a transcription factor belonging to the POU3 family, and it is important for the embryonic development of the neural tube, inner ear and pancreas. In addition, it serves a crucial role in neural stem cell differentiation and reprogramming. The present review aimed to summarize the chromosomal location, species homology, protein molecular structure and tissue distribution of Brn4, in addition to its biological processes, with the aim of providing a reference of its structure and function for further studies, and its potential use as a gene therapy target.
View Figures
View References

Related Articles

Journal Cover

March-2021
Volume 23 Issue 3

Print ISSN: 1791-2997
Online ISSN:1791-3004

Sign up for eToc alerts

Recommend to Library

Copy and paste a formatted citation
x
Spandidos Publications style
Wu Y, Zhang X, Wang J, Jin G and Zhang X: Research progress of the transcription factor Brn4 (Review). Mol Med Rep 23: 179, 2021
APA
Wu, Y., Zhang, X., Wang, J., Jin, G., & Zhang, X. (2021). Research progress of the transcription factor Brn4 (Review). Molecular Medicine Reports, 23, 179. https://doi.org/10.3892/mmr.2020.11818
MLA
Wu, Y., Zhang, X., Wang, J., Jin, G., Zhang, X."Research progress of the transcription factor Brn4 (Review)". Molecular Medicine Reports 23.3 (2021): 179.
Chicago
Wu, Y., Zhang, X., Wang, J., Jin, G., Zhang, X."Research progress of the transcription factor Brn4 (Review)". Molecular Medicine Reports 23, no. 3 (2021): 179. https://doi.org/10.3892/mmr.2020.11818