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Ginger facilitates cell migration and heat tolerance in mouse fibroblast cells

  • Authors:
    • Naotoshi Sugimoto
    • Masanori Katakura
    • Kentaro Matsuzaki
    • Mayumi Miyamoto
    • Eri Sumiyoshi
    • Taizo Wada
    • Akihiro Yachie
    • Hiroyuki Nakamura
    • Osamu Shido
  • View Affiliations / Copyright

    Affiliations: Department of Physiology, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, Ishikawa 920‑8640, Japan, Department of Environmental Physiology, School of Medicine, Shimane University, Izumo, Shimane 693‑8501, Japan, Department of Pediatrics, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, Ishikawa 920‑8640, Japan, Department of Public Health Pediatrics, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, Ishikawa 920‑8640, Japan
    Copyright: © Sugimoto et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 250
    |
    Published online on: February 2, 2021
       https://doi.org/10.3892/mmr.2021.11889
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Abstract

The components of ginger root (Zingiber officinale Roscoe) are widely used for various medicinal purposes. Several bioactive compounds have been identified in ginger, including 6‑, 8‑ and 10‑gingerols, and 6‑shogaol, which are agonists of the thermo‑sensors transient receptor potential (TRP) cation channel subfamily V member 1 and TRP ankyrin 1. Our previous study demonstrated that ginger powder may affect human metabolism in vivo. However, the effects of the bioactive compounds of ginger on cells have not been completely elucidated. The present study investigated whether ginger powder extracts could modify cell functions in mouse fibroblast cells. The active components of ginger powder extracts were characterized using high‑performance liquid chromatography. The activation of protein kinases, actin assembly, cell migration, expression levels of heat shock proteins (HSPs) and cell viability after heat shock were analyzed in NIH3T3 mouse fibroblast cells. Subsequently, 6‑, 8‑, 10‑ and 12‑gingerols, as well as 6‑, 8‑ and 10‑shogaols, were detected in ginger powder extracts. The levels of phosphorylated Akt, mTOR, ERK and p38 MAPK increased after a 10‑min stimulation with ginger powder extracts. In addition, HSP expression levels, lamellipodia formation occurring at cell edges, cell migration and tolerance against heat shock were facilitated following ginger powder extract stimulation. These results suggest that ginger modified cell functions, including actin assembly and heat tolerance, in vitro.
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1 

Ali BH, Blunden G, Tanira MO and Nemmar A: Some phytochemical, pharmacological and toxicological properties of ginger (Zingiber officinale Roscoe): A review of recent research. Food Chem Toxicol. 46:409–420. 2008. View Article : Google Scholar : PubMed/NCBI

2 

McParlin C, O'Donnell A, Robson SC, Beyer F, Moloney E, Bryant A, Bradley J, Muirhead CR, Nelson-Piercy C, Newbury-Birch D, et al: Treatments for hyperemesis gravidarum and nausea and vomiting in pregnancy: A systematic review. JAMA. 316:1392–1401. 2016. View Article : Google Scholar : PubMed/NCBI

3 

Tao Y, Li W, Liang W and Van Breemen RB: Identification and quantification of gingerols and related compounds in ginger dietary supplements using high-performance liquid chromatography-tandem mass spectrometry. J Agric Food Chem. 57:10014–10021. 2009. View Article : Google Scholar : PubMed/NCBI

4 

Yu Y, Zick S, Li X, Zou P, Wright B and Sun D: Examination of the pharmacokinetics of active ingredients of ginger in humans. AAPS J. 13:417–426. 2011. View Article : Google Scholar : PubMed/NCBI

5 

Pertz HH, Lehmann J, Roth-Ehrang R and Elz S: Effects of ginger constituents on the gastrointestinal tract: Role of cholinergic M3 and serotonergic 5-HT3 and 5-HT4 receptors. Planta Med. 77:973–978. 2011. View Article : Google Scholar : PubMed/NCBI

6 

Miyano K, Eto M, Hitomi S, Matsumoto T, Hasegawa S, Hirano A, Nagabuchi K, Asai N, Uzu M, Nonaka M, et al: The Japanese herbal medicine Hangeshashinto enhances oral keratinocyte migration to facilitate healing of chemotherapy-induced oral ulcerative mucositis. Sci Rep. 10:6252020. View Article : Google Scholar : PubMed/NCBI

7 

Dedov VN, Tran VH, Duke CC, Connor M, Christie MJ, Mandadi S and Roufogalis BD: Gingerols: A novel class of vanilloid receptor (VR1) agonists. Br J Pharmacol. 137:793–798. 2002. View Article : Google Scholar : PubMed/NCBI

8 

Kim YS, Hong CS, Lee SW, Nam JH and Kim BJ: Effects of ginger and its pungent constituents on transient receptor potential channels. Int J Mol Med. 38:1905–1914. 2016. View Article : Google Scholar : PubMed/NCBI

9 

Yin Y, Dong Y, Vu S, Yang F, Yarov-Yarovoy V, Tian Y and Zheng J: Structural mechanisms underlying activation of TRPV1 channels by pungent compounds in gingers. Br J Pharmacol. 176:3364–3377. 2019.PubMed/NCBI

10 

Bandell M, Macpherson LJ and Patapoutian A: From chills to chilis: Mechanisms for thermosensation and chemesthesis via thermoTRPs. Curr Opin Neurobiol. 17:490–497. 2007. View Article : Google Scholar : PubMed/NCBI

11 

Venkatachalam K and Montell C: TRP channels. Annu Rev Biochem. 76:387–417. 2007. View Article : Google Scholar : PubMed/NCBI

12 

Sugimoto N, Katakura M, Matsuzaki K, Nakamura H, Yachie A and Shido O: Capsaicin partially mimics heat in mouse fibroblast cells in vitro. Naunyn Schmiedebergs Arch Pharmacol. 390:281–289. 2017. View Article : Google Scholar : PubMed/NCBI

13 

Sugimoto N, Matsuzaki K, Katakura M, Nakamura H, Ueda Y, Yachie A and Shido O: Heat attenuates sensitivity of mammalian cells to capsaicin. J Biochem Mol Toxicol. 33:e222882019. View Article : Google Scholar : PubMed/NCBI

14 

Sugimoto N, Shido O, Matsuzaki K, Katakura M, Hitomi Y, Tanaka M, Sawaki T, Fujita Y, Kawanami T, Masaki Y, et al: Long-term heat exposure prevents hypoxia-induced apoptosis in mouse fibroblast cells. Cell Biochem Biophys. 70:301–307. 2014. View Article : Google Scholar : PubMed/NCBI

15 

Sugimoto N, Shido O, Matsuzaki K, Ohno-Shosaku T, Hitomi Y, Tanaka M, Sawaki T, Fujita Y, Kawanami T, Masaki Y, et al: Cellular heat acclimation regulates cell growth, cell morphology, mitogen-activated protein kinase activation, and expression of aquaporins in mouse fibroblast cells. Cell Physiol Biochem. 30:450–457. 2012. View Article : Google Scholar : PubMed/NCBI

16 

Leu H, Sugimoto N, Shimizu M, Toma T, Wada T, Ohta K and Yachie A: Tumor necrosis factor-α modifies the effects of Shiga toxin on glial cells. Int Immunopharmacol. 38:139–143. 2016. View Article : Google Scholar : PubMed/NCBI

17 

Sugimoto N, Takuwa N, Yoshioka K and Takuwa Y: Rho-dependent, Rho kinase-independent inhibitory regulation of Rac and cell migration by LPA1 receptor in Gi-inactivated CHO cells. Exp Cell Res. 312:1899–1908. 2006. View Article : Google Scholar : PubMed/NCBI

18 

Akimoto M, Iizuka M, Kanematsu R, Yoshida M and Takenaga K: Anticancer effect of ginger extract against pancreatic cancer cells mainly through reactive oxygen species-mediated autotic cell death. PLoS One. 10:e01266052015. View Article : Google Scholar : PubMed/NCBI

19 

Kotowski U, Kadletz L, Schneider S, Foki E, Schmid R, Seemann R, Thurnher D and Heiduschka G: 6-shogaol induces apoptosis and enhances radiosensitivity in head and neck squamous cell carcinoma cell lines. Phytother Res. 32:340–347. 2018. View Article : Google Scholar : PubMed/NCBI

20 

Yao C, Oh JH, Oh IG, Park CH and Chung JH: [6]-Shogaol inhibits melanogenesis in B16 mouse melanoma cells through activation of the ERK pathway. Acta Pharmacol Sin. 34:289–294. 2013. View Article : Google Scholar : PubMed/NCBI

21 

Ueda Y, Ii T, Aono Y, Sugimoto N, Shinji S, Yoshida H and Sato M: Membrane dynamics induced by a phosphatidylinositol 3,4,5-trisphosphate optogenetic tool. Anal Sci. 35:57–63. 2019. View Article : Google Scholar : PubMed/NCBI

22 

Le Clainche C and Carlier MF: Regulation of actin assembly associated with protrusion and adhesion in cell migration. Physiol Rev. 88:489–513. 2008. View Article : Google Scholar : PubMed/NCBI

23 

Matozaki M, Saito Y, Yasutake R, Munira S, Kaibori Y, Yukawa A, Tada M and Nakayama Y: Involvement of Stat3 phosphorylation in mild heat shock-induced thermotolerance. Exp Cell Res. 377:67–74. 2019. View Article : Google Scholar : PubMed/NCBI

24 

Morotomi T, Kitamura C, Okinaga T, Nishihara T, Sakagami R and Anan H: Continuous fever-range heat stress induces thermotolerance in odontoblast-lineage cells. Arch Oral Biol. 59:741–748. 2014. View Article : Google Scholar : PubMed/NCBI

25 

Miyamoto M, Matsuzaki K, Katakura M, Hara T, Tanabe Y and Shido O: Oral intake of encapsulated dried ginger root powder hardly affects human thermoregulatory function, but appears to facilitate fat utilization. Int J Biometeorol. 59:1461–1474. 2015. View Article : Google Scholar : PubMed/NCBI

26 

Sugimoto N, Katakura M, Matsuzaki K, Sumiyoshi E, Yachie A and Shido O: Chronic administration of theobromine inhibits mTOR signal in rats. Basic Clin Pharmacol Toxicol. 124:575–581. 2019. View Article : Google Scholar : PubMed/NCBI

27 

Qi Y, Liang X, Dai F, Guan H, Sun J and Yao W: RhoA/ROCK pathway activation is regulated by AT1 receptor and participates in smooth muscle migration and dedifferentiation via promoting actin cytoskeleton polymerization. Int J Mol Sci. 21:53982020. View Article : Google Scholar

28 

Katoh M and Katoh M: Molecular genetics and targeted therapy of WNT-related human diseases (Review). Int J Mol Med. 40:587–606. 2017.PubMed/NCBI

29 

Manning BD and Toker A: AKT/PKB signaling: Navigating the network. Cell. 169:381–405. 2017. View Article : Google Scholar : PubMed/NCBI

30 

Shi X, Wang J, Lei Y, Cong C, Tan D and Zhou X: Research progress on the PI3K/AKT signaling pathway in gynecological cancer (Review). Mol Med Rep. 19:4529–4535. 2019.PubMed/NCBI

31 

Hossain ME, Matsuzaki K, Katakura M, Sugimoto N, Mamun AA, Islam R, Hashimoto M and Shido O: Direct exposure to mild heat promotes proliferation and neuronal differentiation of neural stem/progenitor cells in vitro. PLoS One. 12:e01903562017. View Article : Google Scholar : PubMed/NCBI

32 

Sun Y, Liu WZ, Liu T, Feng X, Yang N and Zhou HF: Signaling pathway of MAPK/ERK in cell proliferation, differentiation, migration, senescence and apoptosis. J Recept Signal Transduct Res. 35:600–604. 2015. View Article : Google Scholar : PubMed/NCBI

33 

Gong X, Luo T, Deng P, Liu Z, Xiu J, Shi H and Jiang Y: Stress-induced interaction between p38 MAPK and HSP70. Biochem Biophys Res Commun. 425:357–362. 2012. View Article : Google Scholar : PubMed/NCBI

34 

Westerheide SD, Raynes R, Powell C, Xue B and Uversky VN: HSF transcription factor family, heat shock response, and protein intrinsic disorder. Curr Protein Pept Sci. 13:86–103. 2012. View Article : Google Scholar : PubMed/NCBI

35 

Sugimoto N, Matsuzaki K, Ishibashi H, Tanaka M, Sawaki T, Fujita Y, Kawanami T, Masaki Y, Okazaki T, Sekine J, et al: Upregulation of aquaporin expression in the salivary glands of heat-acclimated rats. Sci Rep. 3:17632013. View Article : Google Scholar : PubMed/NCBI

36 

Creagh EM, Sheehan D and Cotter TG: Heat shock proteins-modulators of apoptosis in tumour cells. Leukemia. 4:1161–1173. 2000. View Article : Google Scholar

37 

Horowitz M and Assadi H: Heat acclimation-mediated cross-tolerance in cardioprotection: Do HSP70 and HIF-1alpha play a role? Ann N Y Acad Sci. 1188:199–206. 2010. View Article : Google Scholar : PubMed/NCBI

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Copy and paste a formatted citation
Spandidos Publications style
Sugimoto N, Katakura M, Matsuzaki K, Miyamoto M, Sumiyoshi E, Wada T, Yachie A, Nakamura H and Shido O: Ginger facilitates cell migration and heat tolerance in mouse fibroblast cells. Mol Med Rep 23: 250, 2021.
APA
Sugimoto, N., Katakura, M., Matsuzaki, K., Miyamoto, M., Sumiyoshi, E., Wada, T. ... Shido, O. (2021). Ginger facilitates cell migration and heat tolerance in mouse fibroblast cells. Molecular Medicine Reports, 23, 250. https://doi.org/10.3892/mmr.2021.11889
MLA
Sugimoto, N., Katakura, M., Matsuzaki, K., Miyamoto, M., Sumiyoshi, E., Wada, T., Yachie, A., Nakamura, H., Shido, O."Ginger facilitates cell migration and heat tolerance in mouse fibroblast cells". Molecular Medicine Reports 23.4 (2021): 250.
Chicago
Sugimoto, N., Katakura, M., Matsuzaki, K., Miyamoto, M., Sumiyoshi, E., Wada, T., Yachie, A., Nakamura, H., Shido, O."Ginger facilitates cell migration and heat tolerance in mouse fibroblast cells". Molecular Medicine Reports 23, no. 4 (2021): 250. https://doi.org/10.3892/mmr.2021.11889
Copy and paste a formatted citation
x
Spandidos Publications style
Sugimoto N, Katakura M, Matsuzaki K, Miyamoto M, Sumiyoshi E, Wada T, Yachie A, Nakamura H and Shido O: Ginger facilitates cell migration and heat tolerance in mouse fibroblast cells. Mol Med Rep 23: 250, 2021.
APA
Sugimoto, N., Katakura, M., Matsuzaki, K., Miyamoto, M., Sumiyoshi, E., Wada, T. ... Shido, O. (2021). Ginger facilitates cell migration and heat tolerance in mouse fibroblast cells. Molecular Medicine Reports, 23, 250. https://doi.org/10.3892/mmr.2021.11889
MLA
Sugimoto, N., Katakura, M., Matsuzaki, K., Miyamoto, M., Sumiyoshi, E., Wada, T., Yachie, A., Nakamura, H., Shido, O."Ginger facilitates cell migration and heat tolerance in mouse fibroblast cells". Molecular Medicine Reports 23.4 (2021): 250.
Chicago
Sugimoto, N., Katakura, M., Matsuzaki, K., Miyamoto, M., Sumiyoshi, E., Wada, T., Yachie, A., Nakamura, H., Shido, O."Ginger facilitates cell migration and heat tolerance in mouse fibroblast cells". Molecular Medicine Reports 23, no. 4 (2021): 250. https://doi.org/10.3892/mmr.2021.11889
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