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Molecular Medicine Reports
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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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April-2021 Volume 23 Issue 4

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

Semaphorin 3A contributes to sepsis‑induced immunosuppression by impairing CD4+ T cell anergy

Yulei Gao, Chunxue Wang, Ziyi Wang, Wenjie Li, Yancun Liu, Songtao Shou, Yanfen Chai
Article Number: 302
Published online on: 24 February 2021

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Article Open Access

Dual PI3K/mTOR inhibitor NVP‑BEZ235 decreases the proliferation of doxorubicin‑resistant K562 cells

Jie Li, Xiaozi Wang, Chuanbao Ma, Shasha Xu, Mengyao Xu, Jie Yang, Ruicang Wang, Liying Xue
Article Number: 301
Published online on: 24 February 2021

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Article Open Access

circ‑0000212 promotes cell proliferation of colorectal cancer by sponging miR‑491 and modulating FOXP4 expression

Hongyu Wu, Yangbao Tao, Weiyuan Zhang, Guiyu Wang, Qian Zhang
Article Number: 300
Published online on: 24 February 2021

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Article Open Access

Hydrogen sulfide ameliorates doxorubicin‑induced myocardial fibrosis in rats via the PI3K/AKT/mTOR pathway

Liangui Nie, Maojun Liu, Jian Chen, Qian Wu, Yaling Li, Jiali Yi, Xia Zheng, Jingjing Zhang, Chun Chu, Jun Yang
Article Number: 299
Published online on: 24 February 2021

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Article Open Access

Peptidomics analysis revealed that a novel peptide VMP‑19 protects against Ang II‑induced injury in human umbilical vein endothelial cells

Zhongqing Xu, Jingjing Ding, Li Zhang, Xianzhen Feng, Jun Zhou, Xiaoyi Shen, Hong Lu, Lingmei Qian, Xun Li
Article Number: 298
Published online on: 23 February 2021

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Article Open Access

Tetrandrine attenuates ischemia/reperfusion‑induced neuronal damage in the subacute phase

Yu Wang, Xinjun Cai, Zhiheng Wu, Leilei Tang, Lingqun Lu, Yinyin Xu, Xiaogang Bao
Article Number: 297
Published online on: 23 February 2021

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Correction Open Access

[Corrigendum] miR‑182‑5p contributes to radioresistance in naso-pharyngeal carcinoma by regulating BNIP3 expression

Wei He, Hongyan Jin, Qian Liu, Quanxin Sun
Article Number: 296
Published online on: 23 February 2021

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Article Open Access

Rs41291957 polymorphism in the promoter region of microRNA‑143 serves as a prognostic biomarker for patients with intracranial hemorrhage

Xiaobo Yang, Zongduo Guo, Fang Cao, Zhipeng Teng, Zhijian Huang, Xiaochuan Sun
Article Number: 295
Published online on: 23 February 2021

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Article Open Access

Effects of combination treatment with transcranial magnetic stimulation and bone marrow mesenchymal stem cell transplantation or Raf inhibition on spinal cord injury in rats

Sining Feng, Shuai Wang, Shi Sun, Hao Su, Lixin Zhang
Article Number: 294
Published online on: 23 February 2021

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Article Open Access

κ‑opioid receptor agonist U50488H attenuates postoperative cognitive dysfunction of cardiopulmonary bypass rats through the PI3K/AKT/Nrf2/HO‑1 pathway

Jianing Fan, Long Li, Pengxia Qu, Yugang Diao, Yingjie Sun
Article Number: 293
Published online on: 23 February 2021

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Article

Anti‑fibrotic effects and the mechanism of action of miR‑29c in silicosis

Lei Huang, Yang Zhang, Jie Yang, Juan Li, Ju Wu, Faxuan Wang, Yajia Lan, Qin Zhang
Article Number: 292
Published online on: 22 February 2021

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Article Open Access

Ginsenoside Rg1 improves cognitive capability and affects the microbiota of large intestine of tree shrew model for Alzheimer's disease

Yuqian Guo, Limei Wang, Jiangli Lu, Jianlin Jiao, Yi Yang, Hongbin Zhao, Zhang Liang, Hong Zheng
Article Number: 291
Published online on: 22 February 2021

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Article Open Access

Novel insights into di‑(2‑ethylhexyl)phthalate activation: Implications for the hypothalamus‑pituitary‑thyroid axis

Haoyu Wu, Wanying Zhang, Yunbo Zhang, Zhen Kang, Xinxiunan Miao, Xiaolin Na
Article Number: 290
Published online on: 22 February 2021

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Article Open Access

Bioinformatics analysis of differentially expressed proteins in alcoholic fatty liver disease treated with recombinant human cytoglobin

Zi-Rong Zhang, Zheng-Gen Yang, Yan-Mei Xu, Zhe-Yan Wang, Jian Wen, Bo-Hong Chen, Ping Wang, Wei Wei, Zhen Li, Wen-Qi Dong
Article Number: 289
Published online on: 22 February 2021

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Article Open Access

Nerve growth factor regulates liver cancer cell polarity and motility

Haihua Lin, Huanjun Huang, Yuhong Yu, Weibin Chen, Shaomin Zhang, Yuanzhi Zhang
Article Number: 288
Published online on: 19 February 2021

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Article

Isoacteoside attenuates acute kidney injury induced by severe acute pancreatitis

Bin Wang, Xi-Han Li, Zhang Song, Min-Li Li, Xiao-Wei Wu, Mei-Xia Guo, Xiao-Hua Zhang, Xiao-Ping Zou
Article Number: 287
Published online on: 19 February 2021

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Article Open Access

Hyperoside protects cardiomyocytes against hypoxia‑induced injury via upregulation of microRNA‑138

Siyi He, Xiaoqiang Yin, Fan Wu, Shaojie Zeng, Feng Gao, Mei Xin, Jian Wang, Jie Chen, Le Zhang, Jinbao Zhang
Article Number: 286
Published online on: 19 February 2021

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Article Open Access

Size changes in miR‑21 knockout mice: Geometric morphometrics on teeth, alveolar bone and mandible

Uwe Yacine Schwarze, Yuxin Ni, Yanmin Zhou, Lucia Terlecki‑Ζaniewicz, Markus Schosserer, Matthias Hackl, Johannes Grillari, Reinhard Gruber
Article Number: 285
Published online on: 18 February 2021

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Article Open Access

Urantide decreases hepatic steatosis in rats with experimental atherosclerosis via the MAPK/Erk/JNK pathway

Haipeng Cui, Yingxue Lin, Lide Xie, Juan Zhao
Article Number: 284
Published online on: 18 February 2021

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Article Open Access

Inhibiting miR‑1 attenuates pulmonary arterial hypertension in rats

Yun Liu, Yong Li, Jinhai Li, Xiangrong Zuo, Quan Cao, Weiping Xie, Hong Wang
Article Number: 283
Published online on: 18 February 2021

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Article Open Access

Dynamic changes of inflammation and apoptosis in cerebral ischemia‑reperfusion injury in mice investigated by ferumoxytol‑enhanced magnetic resonance imaging

Lihua Zhuang, Yingnan Kong, Shuohui Yang, Fang Lu, Zhigang Gong, Songhua Zhan, Mengxiao Liu
Article Number: 282
Published online on: 18 February 2021

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Correction Open Access

[Corrigendum] Evaluation of eight reference genes for quantitative polymerase chain reaction analysis in human T lymphocytes co‑cultured with mesenchymal stem cells

Xiuying Li, Qiwei Yang, Jinping Bai, Yali Xuan, Yimin Wang
Article Number: 281
Published online on: 17 February 2021

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Article Open Access

CART mitigates oxidative stress and DNA damage in memory deficits of APP/PS1 mice via upregulating β‑amyloid metabolism‑associated enzymes

Hui Jiang, Fengnan Niu, Yan Zheng, Yun Xu
Article Number: 280
Published online on: 17 February 2021

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Article Open Access

Yuan‑zhi‑san inhibits tau protein aggregation in an Aβ1‑40‑induced Alzheimer's disease rat model via the ubiquitin‑proteasome system

Bin Li, Pei-Jun Xie, Yan-Wei Hao, Yu Guo, Jun-Rong Yu, Dao-Yin Gong, Jing Guo, Jin-Hao Zeng, Yi Zhang
Article Number: 279
Published online on: 15 February 2021

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Article

A large dose of methamphetamine inhibits drug‑evoked synaptic plasticity via ER stress in the hippocampus

Guang Chen, Gang Yu, Zheng Yong, Hui Yan, Ruibin Su, Huijun Wang
Article Number: 278
Published online on: 11 February 2021

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Article

Grap2 cyclin D interacting protein negatively regulates CREB‑binding protein, inhibiting fibroblast‑like synoviocyte growth

Hidetoshi Fujita, Satoko Aratani, Toshihiro Nakajima
Article Number: 277
Published online on: 11 February 2021

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Article Open Access

MicroRNA‑138‑5p drives the progression of heart failure via inhibiting sirtuin 1 signaling

Shuai Sun, Chun Wang, Jianxin Weng
Article Number: 276
Published online on: 11 February 2021

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Article Open Access

Genotype variant screening and phenotypic analysis of FBN1 in Chinese patients with isolated ectopia lentis

Yijing Zhou, Dongwei Guo, Qianzhong Cao, Xinyu Zhang, Guangming Jin, Danying Zheng
Article Number: 275
Published online on: 10 February 2021

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Article Open Access

Prenatal ethanol exposure impairs the formation of radial glial fibers and promotes the transformation of GFAPδ‑positive radial glial cells into astrocytes

Yu Li, Li-Na Zhang, Li Chong, Yue Liu, Feng-Yu Xi, Hong Zhang, Xiang-Long Duan
Article Number: 274
Published online on: 09 February 2021

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Article Open Access

Schistosoma japonicum cystatin suppresses osteoclastogenesis via manipulating the NF‑κB signaling pathway

Yu Chen, Bangguo Wei, Panpan Xu, Huadong Tang, Langlang Yang, Yuhang Wang, Yingxiao Fu, Xiaodi Yang, Yingji Mao
Article Number: 273
Published online on: 09 February 2021

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Correction Open Access

[Corrigendum] Long non‑coding RNA PITPNA‑AS1 silencing suppresses proliferation, metastasis and epithelial‑mesenchymal transition in non‑small cell lung cancer cells by targeting microRNA‑32‑5p

Gang Chen, Zhifeng Zheng, Junsheng Li, Peigang Zhang, Zhenjun Wang, Shiping Guo, Jun Ma, Jian  Shen, Huixin Li
Article Number: 272
Published online on: 09 February 2021

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Article

lncRNA PVT1 modulates NLRP3‑mediated pyroptosis in septic acute kidney injury by targeting miR‑20a‑5p

Long-Tian Deng, Qian-Lu Wang, Can Yu, Min Gao
Article Number: 271
Published online on: 09 February 2021

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Article

N1‑methylnicotinamide ameliorates insulin resistance in skeletal muscle of type 2 diabetic mice by activating the SIRT1/PGC‑1α signaling pathway

Yu Chen, Jingfan Zhang, Ping Li, Cong Liu, Ling Li
Article Number: 270
Published online on: 09 February 2021

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Article Open Access

NFIB promotes the progression of gastric cancer by upregulating circMAP7D1 to stabilize HER2 mRNA

Huimin Yang, Zhengzhen Wu, Xin Liu, Min Chen, Xin Zhang, Yong Jiang
Article Number: 269
Published online on: 09 February 2021

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Article Open Access

PWAR6 interacts with miR‑106a‑5p to regulate the osteogenic differentiation of human periodontal ligament stem cells

Juan Xiang, Ying Bian
Article Number: 268
Published online on: 08 February 2021

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Article Open Access

Procyanidin B2 inhibits lipopolysaccharide‑induced apoptosis by suppressing the Bcl‑2/Bax and NF‑κB signalling pathways in human umbilical vein endothelial cells

Da-Qiang Song, Jiao Liu, Fang Wang, Xiao-Fang Li, Ming-Hua Liu, Zhuo Zhang, Shou-Song Cao, Xian Jiang
Article Number: 267
Published online on: 08 February 2021

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Article Open Access

Orexin-A alleviates cerebral ischemia-reperfusion injury by inhibiting endoplasmic reticulum stress-mediated apoptosis

Dandan Xu, Tingting Kong, Baohua Cheng, Rumin Zhang, Chunqing Yang, Jing Chen, Chunmei Wang
Article Number: 266
Published online on: 08 February 2021

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Article Open Access

Effect of mtDNA depletion from C6 glioma cells and characteristics of the generated C6ρ0 cells

Youcai Jin, Guangxiang Luan, Ji Li, Honglun Wang, Zhenhua Wang, Bo Bai
Article Number: 265
Published online on: 08 February 2021

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Article Open Access

Effects of Cirsium setidens (Dunn) Nakai on the osteogenic differentiation of stem cells

Sayan Deb Dutta, Dinesh K. Patel, Bin Jin, Sun-Il Choi, Ok Hwan Lee, Ki-Taek Lim
Article Number: 264
Published online on: 08 February 2021

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Article Open Access

Downregulated expression levels of USP46 promote the resistance of ovarian cancer to cisplatin and are regulated by PUM2 Retraction in /10.3892/mmr.2024.13297

Lei Xu, Bin Zhang, Wenlan Li
Article Number: 263
Published online on: 08 February 2021

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Review Open Access

Severe acute respiratory syndrome coronavirus 2 for physicians: Molecular characteristics and host immunity (Review)

Jin Shang, Lingyao Du, Ning Han, Duoduo Lv, Jiayi Wang, Hailing Yang, Lang Bai, Hong Tang
Article Number: 262
Published online on: 08 February 2021

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Article Open Access

MicroRNA‑592 promotes cell proliferation, migration and invasion in colorectal cancer by directly targeting SPARC

Zhenguo Pan, Rui Xie, Wei Song, Chengcheng Gao
Article Number: 261
Published online on: 08 February 2021

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Review Open Access

Antiangiogenic therapy in diabetic nephropathy: A double‑edged sword (Review)

Qian-Ru Tao, Ying-Ming Chu, Lan Wei, Chao Tu, Yuan-Yuan Han
Article Number: 260
Published online on: 08 February 2021

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Article Open Access

lncRNA‑MALAT1 promotes high glucose‑induced H9C2 cardiomyocyte pyroptosis by downregulating miR‑141‑3p expression

Aishan Wu, Weili Sun, Fengying Mou
Article Number: 259
Published online on: 08 February 2021

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Article Open Access

Comparison and optimisation of microRNA extraction from the plasma of healthy pregnant women

Victoria L. Parker, Bryony F. Cushen, Eleftherios Gavriil, Benjamin Marshall, Sarah Waite, Allan Pacey, Paul R. Heath
Article Number: 258
Published online on: 05 February 2021

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Article Open Access

Promotive role of microRNA‑150 in hippocampal neurons apoptosis in vascular dementia model rats

Chengqun Wei, Xiuzhi Xu, Hongyan Zhu, Xiuyan Zhang, Zhan Gao
Article Number: 257
Published online on: 05 February 2021

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Article Open Access

Transient forebrain ischemia under hyperthermic condition accelerates memory impairment and neuronal death in the gerbil hippocampus by increasing NMDAR1 expression

Bora Kim, Ji Hyeon Ahn, Dae Won Kim, Tae-Kyeong Lee, Yoon Sung Kim, Myoung Cheol Shin, Jun Hwi Cho, Young-Myeong Kim, Joon Ha Park, Il Jun Kang, Jae-Chul Lee, Moo-Ho Won
Article Number: 256
Published online on: 04 February 2021

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Article Open Access

Circ‑TOP2A acts as a ceRNA for miR‑346 and contributes to glioma progression via the modulation of sushi domain‑containing 2

Junzhi Sang, Xing Li, Luting Lv, Chunyu Zhang, Xiaoqian Zhang, Guoan Li
Article Number: 255
Published online on: 04 February 2021

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Article Open Access

Critical implication of the PTEN/PI3K/AKT pathway during BMP2-induced heterotopic ossification

Jun Dong, Xiqiang Xu, Qingyu Zhang, Zenong Yuan, Bingyi Tan
Article Number: 254
Published online on: 03 February 2021

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Article Open Access

MicroRNA‑186‑5p downregulation inhibits osteoarthritis development by targeting MAPK1

Qing Li, Mingjie Wu, Guofang Fang, Kuangwen Li, Wengang  Cui, Liang Li, Xia Li, Junsheng Wang, Yanhong Cang
Article Number: 253
Published online on: 03 February 2021

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Article Open Access

Comparison of steroid hormones in three different preeclamptic models

Ye Young Shin, Sung-Min An, Jea Sic Jeong, Seung Yun Yang, Geun-Shik Lee, Eui-Ju Hong, Eui-Bae Jeung, Seung Chul Kim, Beum-Soo An
Article Number: 252
Published online on: 02 February 2021

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Article Open Access

Benchmarking of next and third generation sequencing technologies and their associated algorithms for de novo genome assembly

Marios Gavrielatos, Konstantinos Kyriakidis, Demetrios A. Spandidos, Ioannis Michalopoulos
Article Number: 251
Published online on: 02 February 2021

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Article Open Access

Ginger facilitates cell migration and heat tolerance in mouse fibroblast cells

Naotoshi Sugimoto, Masanori Katakura, Kentaro Matsuzaki, Mayumi Miyamoto, Eri Sumiyoshi, Taizo Wada, Akihiro Yachie, Hiroyuki Nakamura, Osamu Shido
Article Number: 250
Published online on: 02 February 2021

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Article

Diagnostic value of microRNA‑125b in peripheral blood mononuclear cells for pulmonary tuberculosis

Xiaolu Sun, Kai Liu, Xinhong Wang, Tianhua Zhang, Xiaomou Li, Yan Zhao
Article Number: 249
Published online on: 01 February 2021

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Article

Apoptotic effects of alisol B 23‑acetate on gastric cancer cells

Min Ji Kwon, Jeong Nam Kim, Min Jae Lee, Woo   Kyung Kim, Joo Hyun Nam, Byung Joo Kim
Article Number: 248
Published online on: 01 February 2021

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Article

ER stress mediated‑autophagy contributes to neurological dysfunction in traumatic brain injury via the ATF6 UPR signaling pathway

Da-Yong Wang, Ming-Yan Hong, Jian Pei, Yun-He Gao, Yu Zheng, Xiang Xu
Article Number: 247
Published online on: 01 February 2021

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Article Open Access

GINS2 affects cell proliferation, apoptosis, migration and invasion in thyroid cancer via regulating MAPK signaling pathway

Saifei He, Miao Zhang, Ying Ye, Yanan Song, Xing Ma, Guoyu Wang, Juhua Zhuang, Wei Xia, Bin Zhao
Article Number: 246
Published online on: 01 February 2021

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Article Open Access

MYCN‑amplified neuroblastoma cell‑derived exosomal miR‑17‑5p promotes proliferation and migration of non‑MYCN amplified cells Corrigendum in /10.3892/mmr.2024.13349

Weiming Chen, Xiwei Hao, Binyi Yang, Yuezhen Zhang, Lingyun Sun, Yanan  Hua, Li Yang, Jiabin Yu, Jing Zhao, Lin Hou, Hongting Lu
Article Number: 245
Published online on: 01 February 2021

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Article Open Access

Astragaloside IV improves angiogenesis under hypoxic conditions by enhancing hypoxia‑inducible factor‑1α SUMOylation

Baoshen Wang, Chunyan Zhang, Dongmei Chu, Xiaofang Ma, Tian Yu, Xiaozhi Liu, Changqing Hu
Article Number: 244
Published online on: 01 February 2021

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Article Open Access

miR‑27a‑3p regulates the inhibitory influence of endothelin 3 on the tumorigenesis of papillary thyroid cancer cells Corrigendum in /10.3892/mmr.2021.12105

Hongxin Chen, Binlin Cai, Kun Liu, Qingquan Hua
Article Number: 243
Published online on: 01 February 2021

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Article Open Access

Notoginsenoside R1 induces DNA damage via PHF6 protein to inhibit cervical carcinoma cell proliferation

Ting Cai, Wenquan Wu, Longhua Guo, Yongwu Xia, Xiaoxin Jiang, Limei Zhang, Feiding Peng, Pinghong Ming
Article Number: 242
Published online on: 01 February 2021

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Article Open Access

Metabolomic profiling identifies a novel mechanism for heat stroke‑related acute kidney injury

Ling Xue, Wenli Guo, Li Li, Santao Ou, Tingting Zhu, Liang Cai, Wenfei Ding, Weihua Wu
Article Number: 241
Published online on: 28 January 2021

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Article Open Access

CDK6 is stimulated by hyperthermia and protects gastric cancer cells from hyperthermia‑induced damage

Guanghui Liu, Hongchao Zhao, Qingqing Ding, Haohao Li, Tao Liu, Hongwei Yang, Yuanhua Liu
Article Number: 240
Published online on: 28 January 2021

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The potential role and trend of HIF‑1α in intervertebral disc degeneration: Friend or foe? (Review)

Yongjin Li, Shen Liu, Dayu Pan, Baoshan Xu, Xuewu Xing, Hengxing Zhou, Bin Zhang, Suzhe Zhou, Guangzhi Ning, Shiqing Feng
Article Number: 239
Published online on: 28 January 2021

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Inhibition of PDGF-BB reduces alkali-induced corneal neovascularization in mice

Lei Chen, Hongya Wu, Chi Ren, Gaoqin Liu, Wenpeng Zhang, Weiming Liu, Peirong Lu
Article Number: 238
Published online on: 28 January 2021

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MicroRNA‑199a‑3p inhibits ovarian cancer cell viability by targeting the oncogene YAP1 Retraction in /10.3892/mmr.2022.12892

Yanfang He, Xiangyang Yu, Yajuan Tang, Yanjuan Guo, Jinling  Yuan, Jinghe Bai, Tao Yao, Xiongzhi Wu
Article Number: 237
Published online on: 27 January 2021

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[Retracted] LINC01638 silencing inhibits cancer cell proliferation in colorectal adenocarcinoma through interaction with RUNX2

Wenying Zhuo, Dengdi Hu, Xihua Chen, Tian Zhang
Article Number: 236
Published online on: 27 January 2021

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Heme oxygenase‑1 improves the survival of ischemic skin flaps (Review)

Yinhua Zheng, Zhenlan Li, Min Yin, Xu Gong
Article Number: 235
Published online on: 26 January 2021

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Mechanism of herbal medicine on hypertensive nephropathy (Review)

Zhaocheng Dong, Haoran Dai, Zhandong Feng, Wenbin Liu, Yu Gao, Fei Liu, Zihan Zhang, Na Zhang, Xuan Dong, Qihan Zhao, Xiaoshan Zhou, Jieli Du, Baoli Liu
Article Number: 234
Published online on: 26 January 2021

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FBXW7 mediates high glucose‑induced SREBP‑1 expression in renal tubular cells of diabetic nephropathy under PI3K/Akt pathway regulation

Lisha Li, Juxiang Yang, Fan Li, Fan Gao, Lin Zhu, Jun Hao
Article Number: 233
Published online on: 26 January 2021

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Effects of DLX3 on the osteogenic differentiation of induced pluripotent stem cell‑derived mesenchymal stem cells

Junyuan Li, Qiang Lin, Yixin Lin, Renfa Lai, Wen Zhang
Article Number: 232
Published online on: 26 January 2021

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Intrathecal injection of ozone alleviates CCI‑induced neuropathic pain via the GluR6‑NF‑κB/p65 signalling pathway in rats

Weiguang Zhang, Fei Wang, Licai Zhang, Tao Sun, Zhijian Fu
Article Number: 231
Published online on: 26 January 2021

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Involvement of TLR2/4‑MyD88‑NF‑κB signaling pathway in the pathogenesis of intracranial aneurysm

Xuezhi Zhang, Yilv Wan, Jiugeng Feng, Meihua Li, Zhiqun Jiang
Article Number: 230
Published online on: 26 January 2021

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[Retracted] Ferruginol exhibits anticancer effects in OVCAR‑3 human ovary cancer cells by inducing apoptosis, inhibition of cancer cell migration and G2/M phase cell cycle arrest

Wen-Dong Xiong, Jian Gong, Chao Xing
Article Number: 229
Published online on: 26 January 2021

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The microRNA-429/DUSP4 axis regulates the sensitivity of colorectal cancer cells to nintedanib

Guohua Cheng, Yarong Li, Zhaoyu Liu, Xiang Song
Article Number: 228
Published online on: 25 January 2021

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Article

Metabolic remodeling in the right ventricle of rats with severe pulmonary arterial hypertension

Seiichiro Sakao, Eiryo Kawakami, Hiroki Shoji, Akira Naito, Hideki Miwa, Rika Suda, Takayuki Jujo Sanada, Nobuhiro Tanabe, Koichiro Tatsumi
Article Number: 227
Published online on: 25 January 2021

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Journal Cover
April-2026 Volume 33 Issue 4

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Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

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Prostate‑specific membrane antigen: Molecular functions and emerging roles as a therapeutic target (Review)

Ryuta Watanabe, Tomohisa Sakaue, Noriyoshi Miura, Tadahiko Kikugawa, Takashi Saika
Article Number: 122
Published online on: 26 February 2026

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[Retracted] MicroRNA‑486‑5p inhibits the growth of human hypertrophic scar fibroblasts by regulating Smad2 expression

Yingying Shi, Luping Wang, Pijun Yu, Yi Liu, Wei Chen
Article Number: 121
Published online on: 25 February 2026

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Prenatal lipopolysaccharide exposure programs cardiac fibrosis via dysregulating of connexin 43 in offspring rats

Yan Wen, Yao Yuan, Haigang Zhang, Ya Liu
Article Number: 120
Published online on: 24 February 2026

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[Retracted] Upregulated microRNA‑671‑3p promotes tumor progression by suppressing forkhead box P2 expression in non‑small‑cell lung cancer

Zhi-Ying Li, Zi-Zhou Zhang, Hui Bi, Qiu-Di Zhang, Su-Juan Zhang, Lin Zhou, Xiao-Qin Zhu, Jun Zhou
Article Number: 119
Published online on: 16 February 2026

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STAT1 accelerates cutaneous melanoma progression through TUBB4A expression regulation

Rongxin Zhao, Kexin Fang, Xiaofei Zhang, Hongchao Li
Article Number: 118
Published online on: 13 February 2026

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Research progress on long non‑coding RNAs in lung cancer (Review)

Renjie Pan, Chaohui Wang, Yan Tang, Fengzhou Zhong, Yan Zhuang, Qiuxia Zhao
Article Number: 117
Published online on: 12 February 2026

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ULK1 activates NCOA4‑mediated ferritinophagy via the Beclin1/VPS34 complex in cardiomyocyte hypertrophy

Qianhui Zhang, Meitian Zhang, Yongsheng Liu, Pilong Shi, Hanping Qi, Man Jiang, Yonggang Cao, Hongli Sun
Article Number: 116
Published online on: 12 February 2026

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miRNA‑29a inhibits the proliferation of HUVECs by regulating the ITGB1/β‑catenin/c‑Myc pathway

Qi Sun, Wenting Chen, Shan Zhang, Xinni Zhong, Yafen Wu, Yingying Qian, Lei Zhu, Ting Zhang, Wei Li
Article Number: 115
Published online on: 12 February 2026

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Puerarin attenuates myocardial ischemia‑reperfusion injury by inhibiting myocardium pyroptosis via the NRF2/HO‑1 signaling pathway

Xiaoyu Zheng, Jinping Li, Tianyang Hu, Li Tan, Ding Lan, Ying Deng
Article Number: 114
Published online on: 11 February 2026

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Epigenetic crossroads in intervertebral disc degeneration: Unlocking novel therapeutic avenues (Review)

Yang Hou, Lei Liu, Yongfei Guo, Jiangang Shi
Article Number: 113
Published online on: 11 February 2026

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[Retracted] miRNA‑30a‑3p inhibits metastasis and enhances radiosensitivity in esophageal carcinoma by targeting insulin‑like growth factor 1 receptor

Yanxin Fan, Xiuhua Bian, Pudong Qian, Jing Wen, Pengwei Yan, Yanhong Luo, Jing Wu, Qian Zhang
Article Number: 112
Published online on: 09 February 2026

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Circular RNAs in intervertebral disc degeneration: Current insights into mechanisms and therapeutic potentials (Review)

Luyan Wang, Ke Yang, Houjun Zhu, Dachuan Wang, Feng Wang, Xianfa Du
Article Number: 111
Published online on: 05 February 2026

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T‑cadherin and its impact on human diseases (Review)

Yan Song, Xinyi Wang, Yunfei Bian
Article Number: 110
Published online on: 05 February 2026

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CD20 monoclonal antibody‑rituximab for the treatment of diffuse alveolar hemorrhage in children (Review)

Xiaobo Zhang, Xiao Wu, Yan Li, Guangmin Nong
Article Number: 109
Published online on: 05 February 2026

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N6‑methyladenosine reader insulin‑like growth factor 2 mRNA‑binding protein 2 promotes abnormal proliferation of colonic epithelial cells in type 2 diabetes mellitus by regulating midkine

Jieyao Li, Qingsheng Xie, Jihao Xu
Article Number: 108
Published online on: 04 February 2026

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Expression of Concern Open Access

[Expression of Concern] Curcumin suppresses breast tumor angiogenesis by abrogating osteopontin‑induced VEGF expression

Goutam Chakraborty, Shalini Jain, Smita Kale, Remya Raja, Santosh Kumar, Rosalin Mishra, Gopal C. Kundu
Article Number: 107
Published online on: 04 February 2026

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Research status and molecular mechanisms of disulfidptosis in cardiovascular diseases (Review)

Xiao Jin, Zelin Cheng, Xinyue Ding, Zongjun Liu
Article Number: 106
Published online on: 03 February 2026

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Role and mechanism of tetrahedral DNA nanostructures in the repair of urethral injury in rats

Caifen Guo, Jian Li
Article Number: 105
Published online on: 02 February 2026

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[Retracted] MicroRNA‑4500 suppresses tumor progression in non‑small cell lung cancer by regulating STAT3

Zhi-Ying Li, Zi-Zhou Zhang, Hui Bi, Qiu-Di Zhang, Su-Juan Zhang, Lin Zhou, Xiao-Qin Zhu, Jun Zhou
Article Number: 104
Published online on: 02 February 2026

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Integrative bioinformatics and experimental analysis reveals FRA1 as a key mediator of tubulointerstitial inflammation in lupus nephritis

Wenpeng Ni, Jialin He, Zhouyu Zeng, Jialong Ke, Runpei Lin, Jianming Peng, Kunyi Deng, Lijuan Wen, Yanhui Chen, Chilun Zhang, Yanfen Li, Guanghong Gu
Article Number: 103
Published online on: 28 January 2026

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Correction Open Access

[Corrigendum] Resveratrol improves neurological outcome and neuroinflammation following spinal cord injury through enhancing autophagy involving the AMPK/mTOR pathway

Hong-Yu Meng, De-Cheng Shao, Han Li, Xiao-Dan Huang, Guang Yang, Bing Xu, Hai-Yun Niu
Article Number: 102
Published online on: 28 January 2026

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Journal Cover
May-2026 Volume 33 Issue 5

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

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Stabilin‑1: An immunoregulatory scavenger receptor in inflammation and tissue homeostasis (Review)

Xiao-Lei Xiang, Xin-Tong Ye, Yu-Tong Wu, Chen Chen, Chu-Ying Yu, Su-Ting Qian, Dan-Li Cai
Article Number: 152
Published online on: 26 March 2026

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Mechanism and therapeutic prospects of adipose tissue B lymphocytes in obesity and obesity‑associated metabolic diseases (Review)

Hong Wang, Hongyuan Lv, Xiaolin Zhang, Meifang Liu, Liyuan Wang
Article Number: 151
Published online on: 26 March 2026

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Tonsil‑derived mesenchymal stem cell‑derived extracellular vesicles suppress MAPK‑NF‑κB signaling and restore osteogenic differentiation in LPS‑stimulated periodontal ligament fibroblasts

Won-Jung Bae, Su Kang Kim, Han-Soo Kim, Sang Wook Kang, Ju Yeon Ban
Article Number: 150
Published online on: 26 March 2026

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Succinylation modification in diabetes and diabetic complications: Mechanisms and functions (Review)

Yeteng Xiong, Fei Luo, Bingnan Li, Qinfeng Yang
Article Number: 149
Published online on: 26 March 2026

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Polyphyllin II regulates ROS levels and promotes ferroptosis in bladder cancer cells

Quanlai Qiao, Ruifang Guo, Zhonghua Sun, Yaxin Shi, Yuning Xie, Zhiyong Liu
Article Number: 148
Published online on: 26 March 2026

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Veronicastrum sibiricum (L.) Pennell extract alleviates inflammation‑induced muscle atrophy through NLRP3 inflammasome regulation and mitochondrial function restoration

Eunhye Lee, Minjeong Kwon, Ju-Ock Nam
Article Number: 147
Published online on: 26 March 2026

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Role and clinical importance of lactylation in tumors (Review)

Chaowei Zhang, Xinyu Tang, Yuxuan Han, Weiyi Yao, Qing Hong, Yanan Zhu, Na Chen
Article Number: 146
Published online on: 26 March 2026

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Photodynamic therapy: A paradigm shift in overcoming drug‑resistant tuberculosis (Review)

Shuhao Cheng, Yuqing Wang, Jie Yao, Guodong Cheng, Gengzhi Ye, Fapeng Shi, Xiaolei Ma
Article Number: 145
Published online on: 26 March 2026

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Heterogeneous nuclear ribonucleoprotein K in cancer biology and its therapeutic applications (Review)

Yiyu Qin, Yang Zhou
Article Number: 144
Published online on: 26 March 2026

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Retraction Open Access

[Retracted] Na+/K+‑ATPase DR region‑specific antibody protects U251 cells against hypoxia reperfusion‑induced injury via the PI3K/AKT and ERK pathways

Huilin Gong, Pengbiao Lü, Jiangwei Zhang, Dandong Li, Jin Zheng, Jinning Song
Article Number: 143
Published online on: 23 March 2026

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Multi‑omics and their integration in psoriasis research (Review)

Hengyan Zhang, Danping Li, Lijuan Zhu, Heguo Yan, Licong Yang, Xuesong Yang, Ye Zhou
Article Number: 142
Published online on: 23 March 2026

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LDHA protects vascular endothelial cells from oxidative stress‑induced mitochondrial damage via HIF‑1α activation and glycolytic reprogramming

Beibei Dai, Lili Yang, Yu Zhang, Aiyong Yu
Article Number: 141
Published online on: 23 March 2026

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Article

Mechanism of BRCC36 affecting cardiac rupture after acute infarction through the Wnt‑JNK signaling pathway

Yongzhe Guo, Linyan Chen, Shumei Li, Xintao Zhang, Huizhong Lin
Article Number: 140
Published online on: 20 March 2026

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[Corrigendum] Puerarin alleviates the ototoxicity of gentamicin by inhibiting the mitochondria‑dependent apoptosis pathway

Ping Niu, Yuxuan Sun, Shiyi Wang, Guang Li, Xiaomin Tang, Jiaqiang Sun, Chunchen Pan, Jingwu Sun
Article Number: 139
Published online on: 19 March 2026

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Role of liver X receptors in the pathogenesis and treatment of chronic liver disease (Review)

Honghui You, Xiangjun Tang, Xiaoyan Fu, Jiaqi Zhou, Liyuan Wang, Hongxia Zhang, Xianhong Du, Shujuan Liang, Meifang Liu
Article Number: 138
Published online on: 19 March 2026

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Mechanistic insights and therapeutic potential of sphingosine‑1‑phosphate in the development of pulmonary fibrosis (Review)

Yanling Qin, Chenqi Tang, Sen Tan, Guangnan Liu
Article Number: 137
Published online on: 18 March 2026

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Advances in the biological functions of miR‑205 in various diseases (Review)

Dandan Chai, Hua Du, Yingxu Shi
Article Number: 136
Published online on: 18 March 2026

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Retraction Open Access

[Retracted] MicroRNA‑25‑3p regulates human nucleus pulposus cell proliferation and apoptosis in intervertebral disc degeneration by targeting Bim

Zhifang Zhao, Jie Zheng, Youchen Ye, Kefeng Zhao, Ruozhang Wang, Ran Wang
Article Number: 135
Published online on: 16 March 2026

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Precision medicine approach to coronary artery disease: Haptoglobin phenotype‑guided risk assessment

Zhengxin He, Hong Liu, Keran Jia, Daxin Lei, Liyun An, Jia Wang, Fukun Wang
Article Number: 134
Published online on: 12 March 2026

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Expression of Concern Open Access

[Expression of Concern] Dexmedetomidine protects against sepsis‑associated encephalopathy through Hsp90/AKT signaling

Lijun Yin, Xuejun Chen, Hongbo Ji, Shunli Gao
Article Number: 133
Published online on: 11 March 2026

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Glucose‑driven TRIB3 enhances the tumorigenic potential of colon cancer via the PI3K/AKT pathway

Yunting Bai, Xuying Huang, Guangyu An, Yang Ge, Rui Yan, Dan Yu
Article Number: 132
Published online on: 10 March 2026

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[Retracted] miR‑222 regulates brain injury and inflammation following intracerebral hemorrhage by targeting ITGB8

Yan-Yan Bai, Jun-Zhi Niu
Article Number: 131
Published online on: 09 March 2026

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Dexmedetomidine protects against myocardial ischemia reperfusion injury by inhibiting the TLR2‑NF‑κB pathway in diabetic mice

Zhengjie Chen, Liangyu Zheng, Gang Chen
Article Number: 130
Published online on: 06 March 2026

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Long non‑coding RNA NKILA regulates the JAK2/STAT3 pathway to exacerbate TGF‑β1‑mediated renal fibrosis

Yu Han, Siqi Yang, Jing Zhang, Yaoguang Wang, Xi Zhao, Huan Liu
Article Number: 129
Published online on: 05 March 2026

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[Retracted] Combination of HSP90 and autophagy inhibitors promotes hepatocellular carcinoma apoptosis following incomplete thermal ablation

Fen Chen, Haiyang Xie, Haiwei Bao, Laurencia Violetta, Shusen Zheng
Article Number: 128
Published online on: 05 March 2026

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Advances regarding physiological functions and mechanisms of theaflavin‑3,3'‑digallate (Review)

Teng Ma, Siwei Zhang, Miaomiao Xiao, Zhijian Ma, Junhong Guan
Article Number: 127
Published online on: 04 March 2026

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Mechanisms and therapeutic potential of glycyrrhizic acid: Insights into key signaling pathways and disease modulation (Review)

Jinjin Yu, Huiheng Qu, Weicheng Xu, Yiming Fang, Nan Wang, Wei Shi
Article Number: 126
Published online on: 04 March 2026

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Pyroptosis in cerebral ischemia‑reperfusion injury: Molecular mechanisms and therapeutic implications (Review)

Ze Li, Qiuli Ming, Tianyu Yang, Mengna Liu, Linpeng Fu, Jingshuang Yang, Zhaofeng Lu
Article Number: 125
Published online on: 04 March 2026

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Characteristics of chromosomal instability‑related lncRNAs associated with progression and prognosis in breast cancer

Qi Chen, Hui Chen, Hui Yang, Yin Tao, Xiaolan Zhu
Article Number: 124
Published online on: 04 March 2026

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Correction Open Access

[Corrigendum] Associations between Huwe1 and autophagy in rat cerebral neuron oxygen‑glucose deprivation and reperfusion injury 

Guo-Qian He, Yan Chen, Hui-Juan Liao, Wen-Ming Xu, Wei Zhang, Guo-Lin He
Article Number: 123
Published online on: 26 February 2026

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