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Transcriptomic alterations in malignant pleural mesothelioma cells in response to long‑term treatment with bullfrog sialic acid‑binding lectin

  • Authors:
    • Takeo Tatsuta
    • Arisu Nakasato
    • Shigeki Sugawara
    • Masahiro Hosono
  • View Affiliations / Copyright

    Affiliations: Division of Cell Recognition, Institute of Molecular Biomembrane and Glycobiology, Tohoku Medical and Pharmaceutical University, Sendai, Miyagi 981‑8558, Japan
    Copyright: © Tatsuta et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 467
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    Published online on: April 19, 2021
       https://doi.org/10.3892/mmr.2021.12106
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Abstract

Malignant pleural mesothelioma (MPM) is a universally lethal type of cancer that is increasing in incidence worldwide; therefore, the development of new drugs for MPM is an urgent task. Bullfrog sialic acid‑binding lectin (cSBL) is a multifunctional protein that has carbohydrate‑binding and ribonuclease activities. cSBL exerts marked antitumor activity against numerous types of cancer cells, with low toxicity to normal cells. Although in vitro and in vivo studies revealed that cSBL was effective against MPM, the mechanism by which cSBL exerts antitumor effects is not fully understood. To further understand the mechanism of action of cSBL, the present study aimed to identify the key molecules whose expression was affected by cSBL. The present study established cSBL‑resistant MPM cells. Microarray analyses revealed that there were significant pleiotropic changes in the expression profiles of several genes, including multiple genes involved in metabolic pathways in cSBL‑resistant cells. Furthermore, the expression of some members of the aldo‑keto reductase family was revealed to be markedly downregulated in these cells. Among these, it was particularly interesting that cSBL action reduced the level of AKR1B10, which has been reported as a biomarker candidate for MPM prognosis. These findings revealed novel aspects of the effect of cSBL, which may contribute to the development of new therapeutic strategies for MPM.
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View References

1 

Cakiroglu E and Senturk S: Genomics and functional genomics of malignant pleural mesothelioma. Int J Mol Sci. 21:63422020. View Article : Google Scholar : PubMed/NCBI

2 

Cugell DW and Kamp DW: Asbestos and the pleura: A review. Chest. 125:1103–1117. 2004. View Article : Google Scholar : PubMed/NCBI

3 

Thanh TD, Van Tho N, Lam NS, Dung NH, Tabata C and Nakano Y: Simian virus 40 may be associated with developing malignant pleural mesothelioma. Oncol Lett. 11:2051–2056. 2016. View Article : Google Scholar : PubMed/NCBI

4 

Farioli A, Ottone M, Morganti AG, Compagnone G, Romani F, Cammelli S, Mattioli S and Violante FS: Radiation-induced mesothelioma among long-term solid cancer survivors: A longitudinal analysis of SEER database. Cancer Med. 5:950–959. 2016. View Article : Google Scholar : PubMed/NCBI

5 

Yap TA, Aerts JG, Popat S and Fennell DA: Novel insights into mesothelioma biology and implications for therapy. Nat Rev Cancer. 17:475–488. 2017. View Article : Google Scholar : PubMed/NCBI

6 

Van Meerbeeck JP, Gaafar R, Manegold C, Van Klaveren RJ, Van Marck EA, Vincent M, Legrand C, Bottomley A, Debruyne C, Giaccone G, et al: Randomized phase III study of cisplatin with or without raltitrexed in patients with malignant pleural mesothelioma: An intergroup study of the European organisation for research and treatment of cancer lung cancer group and the National Cancer Institute. J Clin Oncol. 23:6881–6889. 2005. View Article : Google Scholar : PubMed/NCBI

7 

Vogelzang NJ, Rusthoven JJ, Symanowski J, Denham C, Kaukel E, Ruffie P, Gatzemeier U, Boyer M, Emri S, Manegold C, et al: Phase III study of pemetrexed in combination with cisplatin versus cisplatin alone in patients with malignant pleural mesothelioma. J Clin Oncol. 21:2636–2644. 2003. View Article : Google Scholar : PubMed/NCBI

8 

Wright K: FDA approves nivolumab plus ipilimumab for the treatment of advanced HCC. Oncology (Willist Park). 34:6936062020.

9 

Shukla A, Hillegass JM, MacPherson MB, Beuschel SL, Vacek PM, Pass HI, Carbone M, Testa JR and Mossman BT: Blocking of ERK1 and ERK2 sensitizes human mesothelioma cells to doxorubicin. Mol Cancer. 9:3142010. View Article : Google Scholar : PubMed/NCBI

10 

Pouliquen DL, Nawrocki-Raby B, Nader J, Blandin S, Robard M, Birembaut P and Grégoire M: Evaluation of intracavitary administration of curcumin for the treatment of sarcomatoid mesothelioma. Oncotarget. 8:57552–57573. 2017. View Article : Google Scholar : PubMed/NCBI

11 

Makarov AA and Ilinskaya ON: Cytotoxic ribonucleases: Molecular weapons and their targets. FEBS Lett. 540:15–20. 2003. View Article : Google Scholar : PubMed/NCBI

12 

Fang EF and Ng TB: Ribonucleases of different origins with a wide spectrum of medicinal applications. Biochim Biophys Acta. 1815:65–74. 2011.PubMed/NCBI

13 

Wus Y, Mikulskiq SM, Ardeltll W, Rybakt SM and Youlet RJ: A cytotoxic ribonuclease. J Biol Chem. 268:10686–10693. 1993. View Article : Google Scholar : PubMed/NCBI

14 

Bosch M, Benito A, Ribó M, Puig T, Beaumelle B and Vilanova M: A nuclear localization sequence endows human pancreatic ribonuclease with cytotoxic activity. Biochemistry. 43:2167–2177. 2004. View Article : Google Scholar : PubMed/NCBI

15 

Balandin TG, Edelweiss E, Andronova NV, Treshalina EM, Sapozhnikov AM and Deyev SM: Antitumor activity and toxicity of anti-HER2 immunoRNase scFv 4D5-dibarnase in mice bearing human breast cancer xenografts. Invest New Drugs. 29:22–32. 2011. View Article : Google Scholar : PubMed/NCBI

16 

Nitta K, Ozaki K, Tsukamoto Y, Hosono M, Ogawakonno Y, Kawauchi H, Takayanagi Y, Tsuiki S and Hakomori S: Catalytic lectin (leczyme) from bullfrog (Rana catesbeiana) eggs: Mechanism of tumoricidal activity. Int J Oncol. 9:19–23. 1996.PubMed/NCBI

17 

Nitta K, Takayanagi G, Kawauchi H and Hakomori S: Isolation and characterization of Rana catesbeiana lectin and demonstration of the lectin-binding glycoprotein of rodent and human tumor cell membranes. Cancer Res. 47:4877–83. 1987.PubMed/NCBI

18 

Nitta K, Ozaki K, Tsukamoto Y, Furusawa S, Ohkubo Y, Takimoto H, Murata R, Hosono M, Hikichi N, Sasaki K, et al: Characterization of a Rana catesbeiana lectin-resistant mutant of leukemia P388 cells. Cancer Res. 54:928–934. 1994.PubMed/NCBI

19 

Titani K, Takio K, Kuwada M, Nitta K, Sakakibara F, Kawauchi H, Takayanagi G and Hakomori S: Amino acid sequence of sialic acid binding lectin from frog (Rana catesbeiana) eggs. Biochemistry. 26:2189–2194. 1987. View Article : Google Scholar : PubMed/NCBI

20 

Nitta K, Ozaki K, Ishikawa M, Furusawa S, Hosono M, Kawauchi H, Sasaki K, Takayanagi Y, Tsuiki S and Hakomori S: Inhibition of cell proliferation by Rana catesbeiana and Rana japonica lectins belonging to the ribonuclease superfamily. Cancer Res. 54:920–927. 1994.PubMed/NCBI

21 

Tatsuta T, Sugawara S, Takahashi K, Ogawa Y, Hosono M and Nitta K: Cancer-selective induction of apoptosis by leczyme. Front Oncol. 4:1392014. View Article : Google Scholar : PubMed/NCBI

22 

Tatsuta T, Hosono M, Ogawa Y, Inage K, Sugawara S and Nitta K: Downregulation of Hsp70 inhibits apoptosis induced by sialic acid-binding lectin (leczyme). Oncol Rep. 31:13–18. 2014. View Article : Google Scholar : PubMed/NCBI

23 

Tatsuta T, Sugawara S, Takahashi K, Ogawa Y, Hosono M and Nitta K: Leczyme: A new candidate drug for cancer therapy. Biomed Res Int. 2014:4214152014. View Article : Google Scholar : PubMed/NCBI

24 

Chen JN, Yiang GT, Lin YF, Chou PL, Wu TK, Chang WJ, Chen C and Yu YL: Rana catesbeiana ribonuclease induces cell apoptosis via the caspase-9/-3 signaling pathway in human glioblastoma DBTRG, GBM8901 and GBM8401 cell lines. Oncol Lett. 9:2471–2476. 2015. View Article : Google Scholar : PubMed/NCBI

25 

Tatsuta T, Sato S, Sato T, Sugawara S, Suzuki T, Hara A and Hosono M: Sialic acid-binding lectin from bullfrog eggs exhibits an anti-tumor effect against breast cancer cells including triple-negative phenotype cells. Molecules. 23:27142018. View Article : Google Scholar : PubMed/NCBI

26 

Tatsuta T, Satoh T, Sugawara S, Hara A and Hosono M: Sialic acid-binding lectin from bullfrog eggs inhibits human malignant mesothelioma cell growth in vitro and in vivo. PLoS One. 13:e01906532018. View Article : Google Scholar : PubMed/NCBI

27 

Tatsuta T, Hosono M, Sugawara S, Kariya Y, Ogawa Y, Hakomori S and Nitta K: Sialic acid-binding lectin (leczyme) induces caspase-dependent apoptosis-mediated mitochondrial perturbation in Jurkat cells. Int J Oncol. 43:1402–1412. 2013. View Article : Google Scholar : PubMed/NCBI

28 

Tatsuta T, Hosono M, Miura Y, Sugawara S, Kariya Y, Hakomori S and Nitta K: Involvement of ER stress in apoptosis induced by sialic acid-binding lectin (leczyme) from bullfrog eggs. Int J Oncol. 43:1799–1808. 2013. View Article : Google Scholar : PubMed/NCBI

29 

Kariya Y, Tatsuta T, Sugawara S, Kariya Y, Nitta K and Hosono M: RNase activity of sialic acid-binding lectin from bullfrog eggs drives antitumor effect via the activation of p38 MAPK to caspase3/7 signaling pathway in human breast cancer cells. Int J Oncol. 49:1334–1342. 2016. View Article : Google Scholar : PubMed/NCBI

30 

Tatsuta T, Hosono M, Takahashi K, Omoto T, Kariya Y, Sugawara S, Hakomori S and Nitta K: Sialic acid-binding lectin (leczyme) induces apoptosis to malignant mesothelioma and exerts synergistic antitumor effects with TRAIL. Int J Oncol. 44:377–384. 2014. View Article : Google Scholar : PubMed/NCBI

31 

Satoh T, Tatsuta T, Sugawara S, Hara A and Hosono M: Synergistic anti-tumor effect of bullfrog sialic acid-binding lectin and pemetrexed in malignant mesothelioma. Oncotarget. 8:42466–42477. 2017. View Article : Google Scholar : PubMed/NCBI

32 

Altomare DA, Rybak SM, Pei J, Maizel JV, Cheung M, Testa JR and Shogen K: Onconase responsive genes in human mesothelioma cells: Implications for an RNA damaging therapeutic agent. BMC Cancer. 10:342010. View Article : Google Scholar : PubMed/NCBI

33 

Vert A, Castro J, Ribó M, Benito A and Vilanova M: Activating transcription factor 3 is crucial for antitumor activity and to strengthen the antiviral properties of Onconase. Oncotarget. 8:11692–11707. 2017. View Article : Google Scholar : PubMed/NCBI

34 

Vert A, Castro J, Ribó M, Benito A and Vilanova M: A nuclear-directed human pancreatic ribonuclease (PE5) targets the metabolic phenotype of cancer cells. Oncotarget. 7:18309–18324. 2016. View Article : Google Scholar : PubMed/NCBI

35 

Bolstad BM, Irizarry RA, Astrand M and Speed TP: A comparison of normalization methods for high density oligonucleotide array data based on variance and bias. Bioinformatics. 19:185–193. 2003. View Article : Google Scholar : PubMed/NCBI

36 

Gentleman R, Carey V, Bates D, Bolstad B, Dettling M, Dudoit S, Ellis B, Gautier L, Ge Y, Gentry J, et al: Bioconductor: Open software development for computational biology and bioinformatics. Genome Biol. 5:R802004. View Article : Google Scholar : PubMed/NCBI

37 

Dudoit S, Gentleman RC and Quackenbush J: Open source software for the analysis of microarray data. Biotechniques. 34:496–501. 2003. View Article : Google Scholar : PubMed/NCBI

38 

Edgar R, Domrachev M and Lash AE: Gene Expression Omnibus: NCBI gene expression and hybridization array data repository. Nucleic Acids Res. 30:207–210. 2002. View Article : Google Scholar : PubMed/NCBI

39 

Ashburner M, Ball CA, Blake JA, Botstein D, Butler H, Cherry JM, Davis AP, Dolinski K, Dwight SS, Eppig JT, et al: Gene ontology: Tool for the unification of biology. The Gene Ontology Consortium. Nat Genet. 25:25–29. 2000. View Article : Google Scholar : PubMed/NCBI

40 

The Gene Ontology Consortium, . The Gene Ontology Resource: 20 years and still GOing strong. Nucleic Acids Res. 47:D330–D338. 2019. View Article : Google Scholar : PubMed/NCBI

41 

Kanehisa M: KEGG: Kyoto encyclopedia of genes and genomes. Nucleic Acids Res. 28:27–30. 2000. View Article : Google Scholar : PubMed/NCBI

42 

Dennis G Jr, Sherman BT, Hosack DA, Yang J, Gao W, Lane HC and Lempicki RA: DAVID: Database for annotation, visualization, and integrated discovery. Genome Biol. 4:R602003. View Article : Google Scholar

43 

Warde-Farley D, Donaldson SL, Comes O, Zuberi K, Badrawi R, Chao P, Franz M, Grouios C, Kazi F, Lopes CT, et al: The GeneMANIA prediction server: Biological network integration for gene prioritization and predicting gene function. Nucleic Acids Res. 38((Web Server issue)): W214–W220. 2010. View Article : Google Scholar : PubMed/NCBI

44 

Balendiran GK, Martin HJ, El-Hawari Y and Maser E: Cancer biomarker AKR1B10 and carbonyl metabolism. Chem Biol Interact. 178:134–137. 2009. View Article : Google Scholar : PubMed/NCBI

45 

Thuren T: Hepatic lipase and HDL metabolism. Curr Opin Lipidol. 11:277–283. 2000. View Article : Google Scholar : PubMed/NCBI

46 

Takashima S, Tsuji S and Tsujimoto M: Characterization of the second type of human beta-galactoside alpha 2,6-sialyltransferase (ST6Gal II), which sialylates Galβ1,4GlcNAc structures on oligosaccharides preferentially: Genomic analysis of human sialyltransferase genes. J Biol Chem. 277:45719–45728. 2002. View Article : Google Scholar : PubMed/NCBI

47 

Jez JM, Flynn TG and Penning TM: A nomenclature system for the aldo-keto reductase superfamily. Adv Exp Med Biol. 414:579–589. 1997. View Article : Google Scholar : PubMed/NCBI

48 

Barski OA, Tipparaju SM and Bhatnagar A: The aldo-keto reductase superfamily and its role in drug metabolism and detoxification. Drug Metab Rev. 40:553–624. 2008. View Article : Google Scholar : PubMed/NCBI

49 

Mindnich RD and Penning TM: Aldo-keto reductase (AKR) superfamily: Genomics and annotation. Hum Genomics. 3:362–370. 2009. View Article : Google Scholar : PubMed/NCBI

50 

Fukumoto SI, Yamauchi N, Moriguchi H, Hippo Y, Watanabe A, Shibahara J, Taniguchi H, Ishikawa S, Ito H, Yamamoto S, et al: Overexpression of the aldo-keto reductase family protein AKR1B10 is highly correlated with smokers' non-small cell lung carcinomas. Clin Cancer Res. 11:1776–1785. 2005. View Article : Google Scholar : PubMed/NCBI

51 

Cao D, Fan ST and Chung SSM: Identification and characterization of a novel human aldose reductase- like gene. J Biol Chem. 273:11429–11435. 1998. View Article : Google Scholar : PubMed/NCBI

52 

Distefano JK and Davis B: Diagnostic and prognostic potential of akr1b10 in human hepatocellular carcinoma. Cancers (Basel). 11:4862019. View Article : Google Scholar : PubMed/NCBI

53 

Chung YT, Matkowskyj KA, Li H, Bai H, Zhang W, Tsao MS, Liao J and Yang GY: Overexpression and oncogenic function of aldo-keto reductase family 1B10 (AKR1B10) in pancreatic carcinoma. Mod Pathol. 25:758–766. 2012. View Article : Google Scholar : PubMed/NCBI

54 

Fang CY, Lin YH and Chen CL: Overexpression of AKR1B10 predicts tumor recurrence and short survival in oral squamous cell carcinoma patients. J Oral Pathol Med. 48:712–719. 2019. View Article : Google Scholar : PubMed/NCBI

55 

Huang P, Chandra V and Rastinejad F: Retinoic acid actions through mammalian nuclear receptors. Chem Rev. 114:233–254. 2014. View Article : Google Scholar : PubMed/NCBI

56 

Huang L, He R, Luo W, Zhu YS, Li J, Tan T, Zhang X, Hu Z and Luo D: Aldo-Keto reductase family 1 member B10 inhibitors: Potential drugs for cancer treatment. Recent Pat Anticancer Drug Discov. 11:184–196. 2016. View Article : Google Scholar : PubMed/NCBI

57 

Ruiz FX, Porté S, Parés X and Farrés J: Biological role of aldo-keto reductases in retinoic acid biosynthesis and signaling. Front Pharmacol. 3:582012. View Article : Google Scholar : PubMed/NCBI

58 

Wang C, Yan R, Luo D, Watabe K, Liao DF and Cao D: Aldo-keto reductase family 1 member B10 promotes cell survival by regulating lipid synthesis and eliminating carbonyls. J Biol Chem. 284:26742–26748. 2009. View Article : Google Scholar : PubMed/NCBI

59 

Shen Y, Zhong L, Johnson S and Cao D: Human aldo-keto reductases 1B1 and 1B10: A comparative study on their enzyme activity toward electrophilic carbonyl compounds. Chem Biol Interact. 191:192–198. 2011. View Article : Google Scholar : PubMed/NCBI

60 

Matsunaga T, Suzuki A, Kezuka C, Okumura N, Iguchi K, Inoue I, Soda M, Endo S, El-Kabbani O, Hara A and Ikari A: Aldo-keto reductase 1B10 promotes development of cisplatin resistance in gastrointestinal cancer cells through down-regulating peroxisome proliferator-activated receptor-γ-dependent mechanism. Chem Biol Interact. 256:142–153. 2016. View Article : Google Scholar : PubMed/NCBI

61 

Matsunaga T, Yamane Y, Iida K, Endo S, Banno Y, El-Kabbani O and Hara A: Involvement of the aldo-keto reductase, AKR1B10, in mitomycin-c resistance through reactive oxygen species-dependent mechanisms. Anticancer Drugs. 22:402–408. 2011. View Article : Google Scholar : PubMed/NCBI

62 

Zhong L, Shen H, Huang C, Jing H and Cao D: AKR1B10 induces cell resistance to daunorubicin and idarubicin by reducing C13 ketonic group. Toxicol Appl Pharmacol. 255:40–47. 2011. View Article : Google Scholar : PubMed/NCBI

63 

Mundt F, Johansson HJ, Forshed J, Arslan S, Metintas M, Dobra K, Lehtiö J and Hjerpe A: Proteome screening of pleural effusions identifies galectin 1 as a diagnostic biomarker and highlights several prognostic biomarkers for malignant mesothelioma. Mol Cell Proteomics. 13:701–715. 2014. View Article : Google Scholar : PubMed/NCBI

64 

Usami N, Fukui T, Kondo M, Taniguchi T, Yokoyama T, Mori S, Yokoi K, Horio Y, Shimokata K, Sekido Y and Hida T: Establishment and characterization of four malignant pleural mesothelioma cell lines from Japanese patients. Cancer Sci. 97:387–394. 2006. View Article : Google Scholar : PubMed/NCBI

65 

Suzuki Y, Murakami H, Kawaguchi K, Tanigushi T, Fujii M, Shinjo K, Kondo Y, Osada H, Shimokata K, Horio Y, et al: Activation of the PI3K-AKT pathway in human malignant mesothelioma cells. Mol Med Rep. 2:181–188. 2009.PubMed/NCBI

66 

Endo S, Xia S, Suyama M, Morikawa Y, Oguri H, Hu D, Ao Y, Takahara S, Horino Y, Hayakawa Y, et al: Synthesis of potent and selective inhibitors of Aldo-Keto reductase 1B10 and their efficacy against proliferation, metastasis, and cisplatin resistance of lung cancer cells. J Med Chem. 60:8441–8455. 2017. View Article : Google Scholar : PubMed/NCBI

67 

Plebuch M, Soldan M, Hungerer C, Koch L and Maser E: Increased resistance of tumor cells to daunorubicin after transfection of cDNAs coding for anthracycline inactivating enzymes. Cancer Lett. 255:49–56. 2007. View Article : Google Scholar : PubMed/NCBI

68 

Shiiba M, Yamagami H, Yamamoto A, Minakawa Y, Okamoto A, Kasamatsu A, Sakamoto Y, Uzawa K, Takiguchi Y and Tanzawa H: Mefenamic acid enhances anticancer drug sensitivity via inhibition of aldo-keto reductase 1C enzyme activity. Oncol Rep. 37:2025–2032. 2017. View Article : Google Scholar : PubMed/NCBI

69 

Vasiliou V, Vasiliou K and Nebert DW: Human ATP-binding cassette (ABC) transporter family. Hum Genomics. 3:281–290. 2009. View Article : Google Scholar : PubMed/NCBI

70 

Pasello M, Giudice AM and Scotlandi K: The ABC subfamily A transporters: Multifaceted players with incipient potentialities in cancer. Semin Cancer Biol. 60:57–71. 2020. View Article : Google Scholar : PubMed/NCBI

71 

Iwasaki H, Okabe T, Takara K, Yoshida Y, Hanashiro K and Oku H: Down-regulation of lipids transporter ABCA1 increases the cytotoxicity of nitidine. Cancer Chemother Pharmacol. 66:953–959. 2010. View Article : Google Scholar : PubMed/NCBI

72 

Hudson AL, Weir C, Moon E, Harvie R, Klebe S, Clarke SJ, Pavlakis N and Howell VM: Establishing a panel of chemo-resistant mesothelioma models for investigating chemo-resistance and identifying new treatments for mesothelioma. Sci Rep. 4:61522014. View Article : Google Scholar : PubMed/NCBI

73 

Milosevic V, Kopecka J, Salaroglio IC, Libener R, Napoli F, Izzo S, Orecchia S, Ananthanarayanan P, Bironzo P, Grosso F, et al: Wnt/IL-1β/IL-8 autocrine circuitries control chemoresistance in mesothelioma initiating cells by inducing ABCB5. Int J Cancer. 146:192–207. 2020. View Article : Google Scholar : PubMed/NCBI

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Copy and paste a formatted citation
Spandidos Publications style
Tatsuta T, Nakasato A, Sugawara S and Hosono M: Transcriptomic alterations in malignant pleural mesothelioma cells in response to long‑term treatment with bullfrog sialic acid‑binding lectin. Mol Med Rep 23: 467, 2021.
APA
Tatsuta, T., Nakasato, A., Sugawara, S., & Hosono, M. (2021). Transcriptomic alterations in malignant pleural mesothelioma cells in response to long‑term treatment with bullfrog sialic acid‑binding lectin. Molecular Medicine Reports, 23, 467. https://doi.org/10.3892/mmr.2021.12106
MLA
Tatsuta, T., Nakasato, A., Sugawara, S., Hosono, M."Transcriptomic alterations in malignant pleural mesothelioma cells in response to long‑term treatment with bullfrog sialic acid‑binding lectin". Molecular Medicine Reports 23.6 (2021): 467.
Chicago
Tatsuta, T., Nakasato, A., Sugawara, S., Hosono, M."Transcriptomic alterations in malignant pleural mesothelioma cells in response to long‑term treatment with bullfrog sialic acid‑binding lectin". Molecular Medicine Reports 23, no. 6 (2021): 467. https://doi.org/10.3892/mmr.2021.12106
Copy and paste a formatted citation
x
Spandidos Publications style
Tatsuta T, Nakasato A, Sugawara S and Hosono M: Transcriptomic alterations in malignant pleural mesothelioma cells in response to long‑term treatment with bullfrog sialic acid‑binding lectin. Mol Med Rep 23: 467, 2021.
APA
Tatsuta, T., Nakasato, A., Sugawara, S., & Hosono, M. (2021). Transcriptomic alterations in malignant pleural mesothelioma cells in response to long‑term treatment with bullfrog sialic acid‑binding lectin. Molecular Medicine Reports, 23, 467. https://doi.org/10.3892/mmr.2021.12106
MLA
Tatsuta, T., Nakasato, A., Sugawara, S., Hosono, M."Transcriptomic alterations in malignant pleural mesothelioma cells in response to long‑term treatment with bullfrog sialic acid‑binding lectin". Molecular Medicine Reports 23.6 (2021): 467.
Chicago
Tatsuta, T., Nakasato, A., Sugawara, S., Hosono, M."Transcriptomic alterations in malignant pleural mesothelioma cells in response to long‑term treatment with bullfrog sialic acid‑binding lectin". Molecular Medicine Reports 23, no. 6 (2021): 467. https://doi.org/10.3892/mmr.2021.12106
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