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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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June-2021 Volume 23 Issue 6

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Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

Compound heterozygous CAPN3 variants identified in a family with limb-girdle muscular dystrophy recessive 1

Cheng Zhang, Xueping Zheng, Deguo Lu, Lulu Xu, Fengyuan Che, Shiguo Liu
Article Number: 480
Published online on: 23 April 2021

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Article Open Access

The silencing of FNDC1 inhibits the tumorigenesis of breast cancer cells via modulation of the PI3K/Akt signaling pathway

Chen Yunwen, Gao Shanshan, Ben Zhifei, Chen Saijun, Yin Hua
Article Number: 479
Published online on: 22 April 2021

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Article

Salvianolic acid B inhibits myofibroblast differentiation and extracellular matrix accumulation in nasal polyp fibroblasts via the TGF-β1 signaling pathway

Zhenfeng Sun, Dan Luo, Sang Wang, Ruofei Huang, Pin Dong
Article Number: 478
Published online on: 22 April 2021

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Article

KISS1/KISS1R mediates Sertoli cell apoptosis via the PI3K/AKT signalling pathway in a high‑glucose environment

Dong-Mei Gan, Ping-Ping Zhang, Jian-Ping Zhang, Shu-Xia Ding, Jie Fang, Yang Liu
Article Number: 477
Published online on: 22 April 2021

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Article

HIF‑1α protein SUMOylation is an important protective mechanism of action of hypothermia in hypoxic cardiomyocytes

Huaqin Liu, Xiyun Bian, Meili Xu, Xiaofang Ma, Chunyan Zhang, Jinjin Jiang, Jianfeng Fu, Xiaozhi Liu
Article Number: 476
Published online on: 22 April 2021

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Article Open Access

Expression analysis of progesterone‑regulated miRNAs in cells derived from human glioblastoma

Diana Elisa Velázquez‑Vázquez, Aylin Del Moral‑Morales, Jenie   Marian Cruz‑Burgos, Eduardo  Martínez‑Martínez, Mauricio  Rodríguez‑Dorantes, Ignacio Camacho‑Αrroyo
Article Number: 475
Published online on: 22 April 2021

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Article Open Access

Vascular damage effect of circulating microparticles in patients with ACS is aggravated by type 2 diabetes

Xu-Lan Wang, Wei Zhang, Zhe Li, Wen-Qi Han, Hao-Yu Wu, Qun-Rang Wang, Xin-Hong Liu, Kun Xing, Gong Cheng, Feng-Jun Chang
Article Number: 474
Published online on: 21 April 2021

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Article Open Access

Mangiferin inhibits cell migration and angiogenesis via PI3K/AKT/mTOR signaling in high glucose‑ and hypoxia‑induced RRCECs

Jia Shi, Hongbin Lv, Chen Tang, Yujie Li, Jing Huang, Hong Zhang
Article Number: 473
Published online on: 21 April 2021

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Article Open Access

Role of indoleamine 2,3-dioxygenase in ischemia-reperfusion injury of renal tubular epithelial cells

Theodoros Eleftheriadis, Georgios Pissas, Spyridon Golfinopoulos, Vassilios Liakopoulos, Ioannis Stefanidis
Article Number: 472
Published online on: 21 April 2021

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Article

Downregulation of miR‑106b‑3p increases sensitivity to cisplatin in esophageal cancer cells by targeting TGM3

Yong Zhu, Yun Zhang, Xiaohua Li, Yuntao Su, Nina Wang, Minli Chen, Zhe Yang
Article Number: 471
Published online on: 21 April 2021

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Article Open Access

hsa_circ_0058357 acts as a ceRNA to promote non‑small cell lung cancer progression via the hsa‑miR‑24‑3p/AVL9 axis

Dongshan Wei, Lifang Sun, Wei Feng
Article Number: 470
Published online on: 20 April 2021

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Article Open Access

Hsa_circ_0010957 level is increased and sponges microRNA‑125b in CD4+ T cells of patients with systemic lupus erythematosus

Shan He, Hongwei Du, Yingfang Wang, Xiaowei Shi, Yongwei Zhou
Article Number: 469
Published online on: 20 April 2021

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Article Open Access

H3K14 hyperacetylation‑mediated c‑Myc binding to the miR‑30a‑5p gene promoter under hypoxia postconditioning protects senescent cardiomyocytes from hypoxia/reoxygenation injury

Lingbo Xu, Huiping Zhang, Yanhua Wang, Wei Guo, Lingyu Gu, Anning Yang, Shengchao Ma, Yong Yang, Kai Wu, Yideng Jiang
Article Number: 468
Published online on: 19 April 2021

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Article Open Access

Transcriptomic alterations in malignant pleural mesothelioma cells in response to long‑term treatment with bullfrog sialic acid‑binding lectin

Takeo Tatsuta, Arisu Nakasato, Shigeki Sugawara, Masahiro Hosono
Article Number: 467
Published online on: 19 April 2021

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Correction Open Access

[Corrigendum] miR‑27a‑3p regulates the inhibitory influence of endothelin 3 on the tumorigenesis of papillary thyroid cancer cells

Hongxin Chen, Binlin Cai, Kun Liu, Qingquan Hua
Article Number: 466
Published online on: 19 April 2021

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Article Open Access

Long non‑coding RNA BANCR promotes proliferation, invasion and migration in esophageal squamous cell carcinoma cells via the Raf/MEK/ERK signaling pathway

Xiaogang Yu, Meng Huang, Guodong Yang
Article Number: 465
Published online on: 19 April 2021

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Article Open Access

circ-PRKCI targets miR-1294 and miR-186-5p by downregulating FOXK1 expression to suppress glycolysis in hepatocellular carcinoma

Wenqi Chen, Yuehua Li, Jing Zhong, Gebo Wen
Article Number: 464
Published online on: 19 April 2021

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Article Open Access

miR‑146a reduces depressive behavior by inhibiting microglial activation

Chuan-Peng Liu, Ming Zhong, Jun-Xia Sun, Jin He, Yong Gao, Fang-Xia Qin
Article Number: 463
Published online on: 19 April 2021

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Retraction Open Access

[Retracted] Polyphenol‑rich extract of Saliva chinensis exhibits anticancer activity in different cancer cell lines, and induces cell cycle arrest at the G0/G1‑phase, apoptosis and loss of mitochondrial membrane potential in pancreatic cancer cells

Quan Zhao, Xue-Chen Huo, Fu-Dong Sun, Rui-Qian Dong
Article Number: 462
Published online on: 19 April 2021

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Retraction Open Access

[Retracted] Anticancer activity of taraxerol acetate in human glioblastoma cells and a mouse xenograft model via induction of autophagy and apoptotic cell death, cell cycle arrest and inhibition of cell migration

Jing-Fang Hong, Ying-Fang Song, Zheng Liu, Zhao-Cong Zheng, Hong-Jie Chen, Shou-Sen Wang
Article Number: 461
Published online on: 19 April 2021

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Article Open Access

lncRNA FGD5‑AS1 promotes breast cancer progression by regulating the hsa‑miR‑195‑5p/NUAK2 axis Retraction in /10.3892/mmr.2025.13457

Kun Fang, Zheng-Jie Xu, Su-Xiao Jiang, De-Sheng Tang, Chang-Sheng Yan, You-Yuan Deng, Fu-Ying Zhao
Article Number: 460
Published online on: 16 April 2021

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Article

Structured triglyceride attenuates lung injury and inflammation in lipopolysaccharide‑induced acute lung injury by enhancing GPR120 expression

Haiyun Sun, Yanmin Pang, Dan Zhao, Wenyao Li
Article Number: 459
Published online on: 16 April 2021

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Article Open Access

FOXP3‑induced LINC00885 promotes the proliferation and invasion of cervical cancer cells

Yawen Liu, Haiyan Tu, Lingling Zhang, Jianping Xiong, Ling Li
Article Number: 458
Published online on: 16 April 2021

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Article Open Access

Ginkgolide B‑induced AMPK pathway activation protects astrocytes by regulating endoplasmic reticulum stress, oxidative stress and energy metabolism induced by Aβ1‑42

Jing Wang, Yan Ding, Linwu Zhuang, Zhenzhong Wang, Wei Xiao, Jingbo Zhu
Article Number: 457
Published online on: 16 April 2021

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Article

Effects of S1PR2 antagonist on blood pressure and angiogenesis imbalance in preeclampsia rats

Tengfei Zhang, Danjie Guo, Weiping Zheng, Qunyun Dai
Article Number: 456
Published online on: 16 April 2021

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Review Open Access

Major signaling pathways and key mediators of macrophages in acute kidney injury (Review)

Ning Li, Jiale Chen, Pengtao Wang, Haojun Fan, Shike Hou, Yanhua Gong
Article Number: 455
Published online on: 16 April 2021

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Article Open Access

GTSE1 promotes SNAIL1 degradation by facilitating its nuclear export in hepatocellular carcin oma cells

Shan-Shan Li, Dong-Mei Chen, Lu-Biao Chen, Huan Wei, Jia-Liang Wang, Jian Xiao, Yue-Hua Huang, Yi-Fan Lian
Article Number: 454
Published online on: 15 April 2021

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Article Open Access

hsa‑miR‑5580‑3p inhibits oral cancer cell viability, proliferation and migration by suppressing LAMC2

Rong Fang, Qian Lu, Bo Xu
Article Number: 453
Published online on: 15 April 2021

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Article Open Access

Germacrone induces lung cancer cell apoptosis and cell cycle arrest via the Akt/MDM2/p53 signaling pathway

Yang Zhao, Jie Cai, Kaihu Shi, Hang Li, Jin Du, Dinghui Hu, Zuntao Liu, Wei Wang
Article Number: 452
Published online on: 15 April 2021

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Article

CHFR‑mediated epithelial‑to‑mesenchymal transition promotes metastasis in human breast cancer cells

Guobin Jiang, Hongyan Fang, Xi Shang, Xiaopin Chen, Feilin Cao
Article Number: 451
Published online on: 15 April 2021

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Article Open Access

Musk ketone induces apoptosis of gastric cancer cells via downregulation of sorbin and SH3 domain containing 2

Juan An, Haiyan Wang, Xiaoming Ma, Binwen Hu, Yunfei Yan, Yupeng Yan, Zhanhai Su
Article Number: 450
Published online on: 13 April 2021

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Article Open Access

Itgb3-integrin-deficient mice may not be a sufficient model for patients with Glanzmann thrombasthenia

Dongya Li, Jie Peng, Tiantian Li, Yichen Liu, Min Chen, Xiaofeng Shi
Article Number: 449
Published online on: 13 April 2021

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Article Open Access

Humulus japonicus rescues autistic‑like behaviours in the BTBR T+ Itpr3tf/J mouse model of autism

Hye-Yeon Park, Jun Go, Young-Kyoung Ryu, Dong-Hee Choi, Jung-Ran Noh, Jin-Pyo An, Won-Keun Oh, Pyung-Lim Han, Chul-Ho Lee, Kyoung-Shim Kim
Article Number: 448
Published online on: 13 April 2021

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Article Open Access

Knockdown of lncRNA DLEU1 inhibits the tumorigenesis of oral squamous cell carcinoma via regulation of miR‑149‑5p/CDK6 axis

Tianzhu Lv, Hongjing Liu, Yadong Wu, Wentao Huang
Article Number: 447
Published online on: 13 April 2021

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Article Open Access

Long non‑coding RNA SChLAP1 regulates the proliferation of triple negative breast cancer cells via the miR‑524‑5p/HMGA2 axis

Xiangdong Bai, Shengxiao Zhang, Jun Qiao, Xiaolong Xing, Weina Li, Huanhu Zhang, Jun Xie
Article Number: 446
Published online on: 12 April 2021

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Article Open Access

Tryptophan 2, 3‑dioxygenase promotes proliferation, migration and invasion of ovarian cancer cells

Yuemei Zhao, Fengxing Tao, Jiayu Jiang, Lina Chen, Jizao Du, Xiaoxiao Cheng, Qin He, Shouhui Zhong, Wei Chen, Xiaoli Wu, Rongying Ou, Yunsheng Xu, Kai-Fu Tang
Article Number: 445
Published online on: 12 April 2021

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Article Open Access

miR‑654‑5p inhibits autophagy by targeting ATG7 via mTOR signaling in intervertebral disc degeneration

Shanzheng Wang, Yudong Guo, Xuejun Zhang, Chen Wang
Article Number: 444
Published online on: 12 April 2021

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Article

Zinc‑finger E‑box‑binding homeobox 1 alleviates acute kidney injury by activating autophagy and the AMPK/mTOR pathway

Dehua Sun, Xiaohua Liu, Lijuan Zhu, Bin Zhang
Article Number: 443
Published online on: 12 April 2021

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Article

Temporal changes in the chest based on findings from imaging in severe patients with novel coronavirus pneumonia

Ping Li, Helun Cai, Yong Wang, Lisha Wang, Jiwu He, Yan Dong
Article Number: 442
Published online on: 12 April 2021

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Retraction Open Access

[Retracted] Regulation of the cell cycle and PI3K/Akt/mTOR signaling pathway by tanshinone I in human breast cancer cell lines

Li Wang, Jianzhong Wu, Jianwei Lu, Rong Ma, Dawei Sun, Jinhai Tang
Article Number: 441
Published online on: 12 April 2021

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Retraction Open Access

[Retracted] Anticancer and apoptotic activities of oleanolic acid are mediated through cell cycle arrest and disruption of mitochondrial membrane potential in HepG2 human hepatocellular carcinoma cells

Yue-Yong Zhu, Hong-Yan Huang, Yin-Lian Wu
Article Number: 440
Published online on: 12 April 2021

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Article Open Access

Propofol modulates the proliferation, invasion and migration of bladder cancer cells through the miR‑145‑5p/TOP2A axis Retraction in /10.3892/mmr.2024.13218

Yi Du, Xudong Zhang, Hongwei Zhang, Yiding Chen, Shuying Zhu, Jinjun Shu, Hui Pan
Article Number: 439
Published online on: 09 April 2021

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Article Open Access

Exploration of the hepatoprotective effect and mechanism of magnesium isoglycyrrhizinate in mice with arsenic trioxide‑induced acute liver injury

Miaomiao Liu, Bin Zheng, Panpan Liu, Jianping Zhang, Xi Chu, Chunhui Dong, Jing Shi, Yingran Liang, Li Chu, Yanshuang Liu, Xue Han
Article Number: 438
Published online on: 09 April 2021

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Article Open Access

Astragaloside IV alleviates liver injury in type 2 diabetes due to promotion of AMPK/mTOR‑mediated autophagy

Yunfeng Zhu, Yong Su, Jie Zhang, Yanhua Zhang, Yan Li, Yuli Han, Xianan Dong, Weizu Li, Weiping Li
Article Number: 437
Published online on: 09 April 2021

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Article Open Access

MicroRNA‑524‑5p regulates the proliferation and invasion of HTR‑8/SVneo trophoblasts by targeting NUMB in the Notch signaling pathway

Linmei Zheng, Jie Song, Rong Tang, Xiaoju Chen, Li Wang, Dongcai Wu, Hui Cen, Lei Shi
Article Number: 436
Published online on: 08 April 2021

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Article Open Access

Long non‑coding RNA LINC00460 serves as a potential biomarker and oncogene via regulation of the miR‑320b/PBX3 axis in acute myeloid leukemia

Qiang Zhuang, Zhenlin Jin, Xiangkuo Zheng, Ting Jin, Lina Xiang
Article Number: 435
Published online on: 08 April 2021

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Article Open Access

LncRNA NR024118 is downregulated in sepsis and inhibits LPS‑induced apoptosis of cardiomyocytes

Gang Qin, Liuqing Wei, Fufu Jiang, Jiayan Li, Bo Zhang, Dongxu Pan, Xinglin Lu
Article Number: 434
Published online on: 08 April 2021

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Article Open Access

ROS‑associated mechanism of different concentrations of pinacidil postconditioning in the rat cardiac Nrf2‑ARE signaling pathway

Wei Chen, Mengyuan Deng, Haiying Wang, Ying Wang, Wenjing Zhou, Tian Yu
Article Number: 433
Published online on: 08 April 2021

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Article Open Access

MicroRNA‑29‑3p regulates the β‑catenin pathway by targeting IGF1 to inhibit the proliferation of prolactinoma cells

Jie Xia, Songmei Li, Dianfei Ma, Wenyujie Guo, Hong Long, Weiping Yin
Article Number: 432
Published online on: 08 April 2021

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Article Open Access

Changes in the phosphorylation of nucleotide metabolism‑associated proteins by leukemia inhibitory factor in mouse embryonic stem cells

Hwa-Ryung Song, Han-Kyu Kim, Seung-Gook Kim, Hyung-Jin Lim, Hyun-Yi Kim, Myung-Kwan Han
Article Number: 431
Published online on: 08 April 2021

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Article Open Access

The antidiabetic drug troglitazone protects against PrP (106‑126)‑induced neurotoxicity via the PPARγ‑autophagy pathway in neuronal cells

Ji-Hong Moon, Jeong-Min Hong, Sang-Youel Park
Article Number: 430
Published online on: 07 April 2021

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Article Open Access

Apatinib suppresses the migration, invasion and angiogenesis of hepatocellular carcinoma cells by blocking VEGF and PI3K/AKT signaling pathways

Jifu Song, Zhibin Guan, Chao Song, Maojiang Li, Zhiwei Gao, Yongli Zhao
Article Number: 429
Published online on: 07 April 2021

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Article Open Access

Upregulation of antioxidant and autophagy pathways via NRF2 activation protects spinal cord neurons from ozone damage

Cong Zhang, Shulin Ma, Xu Zhao, Bei Wen, Panpan Sun, Zhijian Fu
Article Number: 428
Published online on: 07 April 2021

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Article Open Access

SEC61G is upregulated and required for tumor progression in human kidney cancer

Hui Meng, Xuewen Jiang, Jian Wang, Zunmeng Sang, Longfei Guo, Gang Yin, Yu Wang
Article Number: 427
Published online on: 07 April 2021

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Article

Radiological and histopathological features of short rib‑polydactyly syndrome type III and identification of two novel DYNC2H1 variants

Chun-Ling Xia, Shi-Qi Xiao, Xue Yang, Cai-Xia Liu, Hao Qiu, Hong-Kun Jiang, Jesse Li‑Ling, Yuan Lyu
Article Number: 426
Published online on: 07 April 2021

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Article Open Access

γ‑irradiated prednisolone promotes apoptosis of liver cancer cells via activation of intrinsic apoptosis signaling pathway

Fatuma Jumapili Ramadhani, Seong Hee Kang, Remigius Ambrose Kawala, Byung Yeoup Chung, Hyoung-Woo Bai, Bo Sun Kang
Article Number: 425
Published online on: 07 April 2021

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Article Open Access

Cryptotanshinone interferes with chondrocyte apoptosis in osteoarthritis by inhibiting the expression of miR‑574‑5p

Songtao Yue, Xiaochuan Su, Junyan Teng, Jiangyi Wang, Malong Guo
Article Number: 424
Published online on: 07 April 2021

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Article

TrkB/C-induced HOXC6 activation enhances the ADAM8-mediated metastasis of chemoresistant colon cancer cells

Ga Bin Park, Sangbong Choi, Yoo Sang Yoon, Daejin Kim
Article Number: 423
Published online on: 07 April 2021

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Article Open Access

Lentivirus vector‑mediated genetic manipulation of oncogenic pathways induces tumor formation in rabbit brain

Farizan Ahmad, Anna Hyvärinen, Agnieszka Pirinen, Venla Olsson, Jaana Rummukainen, Arto Immonen, Johanna Närväinen, Pasi Tuunanen, Timo Liimatainen, Virve Kärkkäinen, Jari Koistinaho, Seppo Ylä‑Herttuala
Article Number: 422
Published online on: 06 April 2021

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Article Open Access

Hsa‑circRNA‑G004213 promotes cisplatin sensitivity by regulating miR‑513b‑5p/PRPF39 in liver cancer Corrigendum in /10.3892/mmr.2021.12359

Ling Qin, Zibo Zhan, Chunxue Wei, Xuemei Li, Tongqin Zhang, Jun Li
Article Number: 421
Published online on: 01 April 2021

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Article Open Access

A novel KCNQ4 gene variant (c.857A>G; p.Tyr286Cys) in an extended family with non‑syndromic deafness 2A

Qiong Li, Pengfei Liang, Shujuan Wang, Wei Li, Jian Wang, Yang Yang, Xiaogang An, Jun Chen, Dingjun Zha
Article Number: 420
Published online on: 01 April 2021

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Phgdh serves a protective role in Il‑1β induced chondrocyte inflammation and oxidative‑stress damage

Hefei Huang, Keting Liu, Hua Ou, Xuankun Qian, Jianshan Wan
Article Number: 419
Published online on: 01 April 2021

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Plasmodium infection prevents recurrence and metastasis of hepatocellular carcinoma possibly via inhibition of the epithelial‑mesenchymal transition

Yun Liang, Xiao Chen, Zhu Tao, Meng Ma, Dickson Adah, Xiaofen Li, Lingling Dai, Wenting Ding, Songwe Fanuel, Siting Zhao, Li Qin, Xiaoping Chen, Xiaowen Zhang
Article Number: 418
Published online on: 31 March 2021

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Acute spinal cord injury: Pathophysiology and pharmacological intervention (Review)

Yi Zhang, Abdullah Al Mamun, Yuan Yuan, Qi Lu, Jun Xiong, Shulin Yang, Chengbiao Wu, Yanqing Wu, Jian Wang
Article Number: 417
Published online on: 31 March 2021

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Berberine inhibits the proliferation, invasion and migration of endometrial stromal cells by downregulating miR‑429

Yongjuan Gu, Zhigang Zhou
Article Number: 416
Published online on: 31 March 2021

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Inhibitory role of ginsenoside Rb2 in endothelial senescence and inflammation mediated by microRNA‑216a

Yutong Chen, Shuting Wang, Shujun Yang, Rongxia Li, Yunyun Yang, Yu Chen, Weili Zhang
Article Number: 415
Published online on: 30 March 2021

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Dioscin inhibits SCC15 cell proliferation via the RASSF1A/MST2/YAP axis

Hui Tian, Xiyan Chen, Yafei Zhang, Ying Wang, Xucheng Fu, Weiting Gu, Yong Wen
Article Number: 414
Published online on: 30 March 2021

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Identification of two novel mutations in the PLCD1 gene in Chinese patients with hereditary leukonychia

Shuzhan Shen, Minhua Shao, Uma Keyal, Xiuli Wang, Ming Li, Guolong Zhang
Article Number: 413
Published online on: 30 March 2021

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ABT‑737, a Bcl‑2 family inhibitor, has a synergistic effect with apoptosis by inducing urothelial carcinoma cell necroptosis Retraction in /10.3892/mmr.2025.13705

Rui Cheng, Xiaolong Liu, Zheng Wang, Kunlong Tang
Article Number: 412
Published online on: 30 March 2021

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Costunolide attenuates oxygen‑glucose deprivation/reperfusion‑induced mitochondrial‑mediated apoptosis in PC12 cells

Lanqing Meng, Huixia Ma, Jinni Meng, Tingting Li, Yafei Zhu, Qipeng Zhao
Article Number: 411
Published online on: 30 March 2021

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3D‑printed Ti6Al4V scaffolds combined with pulse electromagnetic fields enhance osseointegration in osteoporosis

Mingfu Ye, Wenjun Liu, Lihui Yan, Shaolong Cheng, Xiaoxiong Li, Shichong Qiao
Article Number: 410
Published online on: 29 March 2021

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Emerging landscape of circHIPK3 and its role in cancer and other diseases (Review)

Qi Shao, Yong Huang, Cai Zhang, Xiaochan Gao, Shiyang Gao
Article Number: 409
Published online on: 29 March 2021

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Sevoflurane inhibits cell proliferation and migration of glioma by targeting the miR‑27b/VEGF axis

Xi Zhan, Changcheng Lei, Linzhu Yang
Article Number: 408
Published online on: 29 March 2021

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[Corrigendum] A serum microRNA signature as a prognostic factor for patients with advanced NSCLC and its association with tissue microRNA expression profiles

Jing Guo, Rui Meng, Zhongyuan Yin, Pengcheng Li, Rui Zhou, Sheng Zhang, Xiaorong Dong, Li Liu, Gang Wu
Article Number: 407
Published online on: 29 March 2021

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Identification of miR‑25‑3p as a tumor biomarker: Regulation of cellular functions via TOB1 in breast cancer

Tianyi Zhao, Wenjing Meng, Yenlie Chin, Lili Gao, Xiyue Yang, Shuangyu Sun, Xingfang Pan, Lihong He
Article Number: 406
Published online on: 26 March 2021

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Fluorofenidone attenuates paraquat‑induced pulmonary fibrosis by regulating the PI3K/Akt/mTOR signaling pathway and autophagy

Feiya Jiang, Sha Li, Yu Jiang, Zhuo Chen, Tongtong Wang, Wen Liu
Article Number: 405
Published online on: 26 March 2021

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Tanshinone IIA attenuates heart failure via inhibiting oxidative stress in myocardial infarction rats

Ruijuan Chen, Wenli Chen, Xiaoling Huang, Qinglin Rui
Article Number: 404
Published online on: 26 March 2021

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A crosstalk between type 2 innate lymphoid cells and alternative macrophages in lung development and lung diseases (Review)

Lan-Lan Mi, Yue Zhu, Hong-Yan Lu
Article Number: 403
Published online on: 26 March 2021

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Article

Sacubitril/valsartan inhibits ox‑LDL‑induced MALAT1 expression, inflammation and apoptosis by suppressing the TLR4/NF‑κB signaling pathway in HUVECs

Wenlou Bai, Tiantian Huo, Xuefeng Chen, Xuelian Song, Cunliang Meng, Yi Dang, Chunli Rong, Liwen Dou, Xiaoyong Qi
Article Number: 402
Published online on: 26 March 2021

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Paeonol prevents migration and invasion, and promotes apoptosis of cervical cancer cells by inhibiting 5‑lipoxygenase

Shao-Qin Sheng, Lei-Yuan Yu, Xian-Wei Zhou, Hong-Yi Pan, Feng-Ying Hu, Jia-Li Liu
Article Number: 401
Published online on: 26 March 2021

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Role of C14orf166 in viral infection and RNA metabolism and its relationship with cancer (Review)

Qiangxing Chen, Rong Li
Article Number: 400
Published online on: 26 March 2021

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X‑irradiation induces acute and early term inflammatory responses in atherosclerosis‑prone ApoE‑/‑ mice and in endothelial cells

Raghda Ramadan, Michaël Claessens, Ellen Cocquyt, Mohamed Mysara, Elke Decrock, Sarah Baatout, An Aerts, Luc Leybaert
Article Number: 399
Published online on: 25 March 2021

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Molecular insights into the benefits of nicotine on memory and cognition (Review)

Ahmad Alhowail
Article Number: 398
Published online on: 25 March 2021

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Article

Dihydromyricetin inhibits oxidative stress and apoptosis in oxygen and glucose deprivation/reoxygenation‑induced HT22 cells by activating the Nrf2/HO‑1 pathway

Qian Zhang, Jia Wang, Huili Zhang, Tao Zeng
Article Number: 397
Published online on: 25 March 2021

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Article

NF‑κB is negatively associated with Nurr1 to reduce the inflammatory response in Parkinson's disease

Hua Gao, Dan Wang, Sen Jiang, Jieping Mao, Xinling Yang
Article Number: 396
Published online on: 25 March 2021

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June-2026 Volume 33 Issue 6

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Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

Mechanotransducer Piezo1 drives ventilator‑induced lung injury in lung epithelial cells via the calcineurin/NFATc3 pathway

Min Li, Shu-Li Zhang, Feng Yuan, Dan Feng
Article Number: 183
Published online on: 28 April 2026

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Oncogene c‑Myc: From molecular mechanism to targeted therapy (Review)

Jianjun Lu, Jing Zhu, Liqiong Zhang, Xiang Zheng, Shan Yang, Yatong Sang, Mingli Yang, Yu Tang
Article Number: 182
Published online on: 28 April 2026

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Indium (III) chloride inhibits testicular Leydig cell proliferation by disrupting centrosome copy numbers

Chia-Yih Wang, Ping-Jui Su, Kuan-Chih Wang, Ruei-Ci Lin, Min-Yun Ke, Yen-Ni Teng
Article Number: 181
Published online on: 28 April 2026

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Correction Open Access

[Corrigendum] Inhibition of DNA‑PK activity sensitizes A549 cells to X‑ray irradiation by inducing the ATM‑dependent DNA damage response

Lina Yang, Xinrui Yang, Yiwei Tang, Defu Zhang, Lijie Zhu, Shengnan Wang, Bo Wang, Tao Ma
Article Number: 180
Published online on: 27 April 2026

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Natural products and neurocognitive disorders: Mechanistic insights and research advances (Review)

Weiqing Li, Wei Wu, Xiaoqing Huang, Yinghai Liu, Gu Gong, Qingqing Huang
Article Number: 179
Published online on: 27 April 2026

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Research progress and future directions in circadian rhythms for uterine‑related diseases (Review)

Tiantian Ma, Junwei Li, Yi Fang, Tiancheng Xu, Qian Li, Liangjun Xia, Youbing Xia
Article Number: 178
Published online on: 27 April 2026

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Therapeutic potential of tertiary lymphoid structures in breast cancer (Review)

Liangxiao Zhu, Meigui Li, Feng Liu, Fenghou Gao
Article Number: 177
Published online on: 24 April 2026

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Retraction Open Access

[Retracted] Prognostic and predictive roles of microRNA‑411 and its target STK17A in evaluating radiotherapy efficacy and their effects on cell migration and invasion via the p53 signaling pathway in cervical cancer

Wei Wei, Cun Liu
Article Number: 176
Published online on: 22 April 2026

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Insights into nuciferine: A natural multifunctional bioactive alkaloid (Review)

Yulin Liu, Xinye Li, Bo Huang, Xudong Lai, Baoqing Ye, Haixiong Miao, Lixian Zhang, Xifeng Xiong
Article Number: 175
Published online on: 22 April 2026

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Article

Urinary 8‑OHdG and MDA as rapid biodosimetry markers in the lethal/sublethal dose range

Satoru Monzen, Kenji Terada, Yusuke Tawata, Takanori Sato, Nozomi Kousaka, Yasushi Mariya
Article Number: 174
Published online on: 22 April 2026

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[Retracted] Treatment with harmine ameliorates functional impairment and neuronal death following traumatic brain injury  

Zeqi Zhong, Yuan Tao, Hui Yang
Article Number: 173
Published online on: 20 April 2026

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SRSF1 as a promising biomarker and key player in the pathogenesis of Alzheimer's disease

Yanchen Liu, Yi Zhao, Yanting Yao, Dan Liu, Yilei Sun, Weishi Xu, Hongli Yu, Lijun Chi
Article Number: 172
Published online on: 17 April 2026

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RUVBL1 and CRAF promote periodontal ligament stem cell osteogenic differentiation via the MEK/ERK signaling cascade

Xin-Yu Zhang, Peiqi Hao, Ming-Yue Qi, Hui Guo
Article Number: 171
Published online on: 16 April 2026

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Porphyromonas gingivalis triggers lipid metabolism disorders in atherosclerosis through the PPARγ-LXRα‑ABCA1/ABCG1 signaling pathway

Xue-Jing Lin, Min Yao, Wan-Yun Lin, Qin Yuan, Jie Zhou, Wen-Xuan Xia, Yu-Lei Dong, Miao-Miao Zhang, Ming-Wang Cui, Lin-Han Wu, Diwas Sunchuri, Muhammad Zia Ullah Shahid, Zhu-Ling Guo
Article Number: 170
Published online on: 16 April 2026

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[Corrigendum] MicroRNA‑122 acts as tumor suppressor by targeting TRIM29 and blocking the activity of PI3K/AKT signaling in nasopharyngeal carcinoma in vitro

Yan Yang, Qing Li, Lili Guo
Article Number: 169
Published online on: 15 April 2026

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Elevated IgG levels induce an M2‑to‑M1 phenotypic shift in mucosal macrophages and restrict the growth of invasive sphenoid sinus pituitary adenomas

Xingbo Li, Zhuowei Lei, Sihan Li, Linpeng Xu, Quanji Wang, Qian Jiang, Zihan Wang, Huaqiu Zhang, Yimin Huang, Ting Lei
Article Number: 168
Published online on: 14 April 2026

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[Retracted] SUMO1/UBC9‑decreased Nox1 activity inhibits reactive oxygen species generation and apoptosis in diabetic retinopathy

Jiaoli Hu, Pengcheng Xue, Xinbang Mao, Lin Xie, Guodong Li, Zhipeng You
Article Number: 167
Published online on: 14 April 2026

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Potential for anti‑angiogenic therapy targeting the receptor for advanced glycation end products/VEGF axis in ulcerative colitis (Review)

Chen Xu, Yuting Li, Yahua Hong, Dayong Zhou, Kun He, Lianghui Wang, Feng Hong
Article Number: 166
Published online on: 09 April 2026

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[Retracted] Molecular mechanisms underlying mangiferin‑induced apoptosis and cell cycle arrest in A549 human lung carcinoma cells

Wei Shi, Jiagang Deng, Rongsheng Tong, Yong Yang, Xia He, Jianzhen Lv, Hailian Wang, Shaoping Deng, Ping Qi, Dingding Zhang, Yi Wang
Article Number: 165
Published online on: 07 April 2026

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Mechanism of and research progress on alterations in the RET gene in thyroid cancer (Review)

Meng Wei, Rui Wang, Jincan Qian, Qiang Fang, Jun Tao
Article Number: 164
Published online on: 02 April 2026

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Current research progress on extracellular vesicles derived from mesenchymal stem cells in tuberculosis treatment (Review)

Dejun Fan, Yan Yang, Li Yang
Article Number: 163
Published online on: 01 April 2026

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Uremic toxin p‑cresyl sulfate enhances the calcification of aortic valvular interstitial cells via klotho/sirtuin‑1 signaling

Shao-Jung Li, Tzu-Yu Cheng, Yu-Hsun Kao, Wei-Yu Chen, Cheng-Chih Chung, Nguyen Ngoc Trang, Pao-Huan Chen, Yi-Jen Chen
Article Number: 162
Published online on: 01 April 2026

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Exercise‑induced extracellular vesicle microRNA regulates physiological function (Review)

Zhonglei Wang, Wenjue Guo, Haojia He, Yi Zhang, Na Li
Article Number: 161
Published online on: 01 April 2026

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Expression of Concern Open Access

[Expression of Concern] Electroacupuncture at GV20‑GB7 regulates mitophagy to protect against neurological deficits following intracerebral hemorrhage via inhibition of apoptosis

Ruiqiao Guan, Zhihao Li, Xiaohong Dai, Wei Zou, Xueping Yu, Hao Liu, Qiuxin Chen, Wei Teng, Peng Liu, Xiaoying Liu, Shanshan Dong
Article Number: 160
Published online on: 01 April 2026

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Emerging roles of POLR2L of RNA polymerase II dynamics and disease mechanisms (Review)

Beomwoo Lee, Changgyu Son, Sunho Eom, Yuwen Li, Seon-Hwan Kim, Jongsun Park
Article Number: 159
Published online on: 30 March 2026

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Combining bioinformatics prediction with experimental validation to explore the ameliorative effect of Psoralea corylifolia on vitiligo

Chen Zhang, Zhanhong Cao, Mengyang Wei, Xuanxuan Zhu, Yan Yan, Zhenhua Wang, Meng Zhang
Article Number: 158
Published online on: 30 March 2026

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Retraction Open Access

[Retracted] All‑trans‑retinoic acid inhibits chondrogenesis of rat embryo hindlimb bud mesenchymal cells by down­regulating p53 expression

Tao-Gen Zhang, Xue-Dong Li, Guo-Yong Yu, Peng Xie, Yun-Guo Wang, Zhao-Yong Liu, Quan Hong, De-Zhong Liu, Shi-Xin Du
Article Number: 157
Published online on: 30 March 2026

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July-2026 Volume 34 Issue 1

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Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

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Role of the PI3K/AKT signaling pathway in regulating gene expression in rheumatoid arthritis (Review)

Chengzhi Cong, Yuan Wang, Jian Liu, Chao Jin
Article Number: 205
Published online on: 21 May 2026

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Biomarkers of radioresistance in lung cancer: Current insights and future directions (Review)

Fatima Zohra Attouahri, Imane Chaoui, Abdelilah Laraqui, Mohamed Rida Tagajdid, Mohammed Oukabli, Mohammed El Marjany, Meriem Khyatti, Mohammed Attaleb, Mouna Ababou, Khalid Ennibi, Khaoula Errafii, Mohammed El Mzibri
Article Number: 204
Published online on: 21 May 2026

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Epigenetic research methods and animal models for intervertebral disc degeneration (Review)

Xinliang Cui, Li Zeng, Wei Zhang, Leimin Xi, Rui Wang, Diff Jia, Safa, Haoyu Feng, Huidong Jia
Article Number: 203
Published online on: 21 May 2026

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ZBTB16 upregulation maintains copper homeostasis to support esophageal tumor progression

Jingyi Wang, Bin Yang, Shengzu Peng
Article Number: 202
Published online on: 21 May 2026

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Correction Open Access

[Corrigendum] MicroRNA‑1 promotes cartilage matrix synthesis and regulates chondrocyte differentiation via post‑​transcriptional suppression of Ihh expression  

Taoyu Chen, Xianda Che, Pengfei Han, Jiangong Lu, Chunfang Wang, Bin Liang, Ziqi Hou, Xiaochun Wei, Lei Wei, Pengcui Li
Article Number: 201
Published online on: 20 May 2026

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Estrogen deficiency as a common driver and integrative mechanism in osteoporosis‑osteoarthritis comorbidity (Review)

Jian Cheng, Xiaodong Wu, Lu Zhao, Shuai Jiang, Wenjie Zhao, Weishuai Zhang
Article Number: 200
Published online on: 20 May 2026

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Role of RNA 5‑methylcytosine modification in cancer: Insights from coding and non‑coding RNAs (Review)

Qin Jiang, Yi Gong, Mimi Zhai, Tenglong Tang, Sushun Liu
Article Number: 199
Published online on: 20 May 2026

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m6A modification in skeletal system diseases (Review)

Xi Xie, Chen Li, Haotian Zheng, Guang Gan, Xi Gao
Article Number: 198
Published online on: 19 May 2026

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Dynamic regulation of the ‘mitochondria‑immune axis’ in myocardial infarction: Molecular mechanisms driving macrophage polarization through energy metabolism disorders (Review)

Yu Zhang, Hao Feng, Qin Wu, Shuxian Yang, Yundong Jiang, Houping Xu, Li Dong, Xiaolin Li, Hui Chen, Gang Luo
Article Number: 197
Published online on: 19 May 2026

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[Retracted] Homeobox B9 facilitates hypertrophic scar formation via activating the mitogen‑activated protein kinase signaling pathway

Qun Xie, Dandan Liu, Mosheng Yu, Xiaowei Wu, Yueqiang Zhao, Qiang Hu, Qi Wang
Article Number: 196
Published online on: 18 May 2026

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Polysaccharides: Natural candidates for targeting immunometabolic regulation in hepatocellular carcinoma (Review)

Changmei Wu, Jinjin Dou, Xiwu Zhang
Article Number: 195
Published online on: 18 May 2026

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NF‑κB signaling drives Th17‑mediated lacrimal gland injury and tear dysfunction in a murine model of primary Sjögren's syndrome

Jiajun Xie, Huina Zhang, Wenyue Shen, Juan Ye
Article Number: 194
Published online on: 18 May 2026

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POSTN(+) fibroblasts and SPP1(+) macrophages in scar formation: A review of mechanisms and therapeutic targets (Review)

Haotian Wu, Xianglin Dong
Article Number: 193
Published online on: 15 May 2026

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Emerging role of DYRK1A as a target in cardiovascular diseases (Review)

Liqing Yu, Qionghong Cheng, Jun Wu
Article Number: 192
Published online on: 15 May 2026

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[Retracted] Resveratrol pretreatment attenuates traumatic brain injury in rats by suppressing NLRP3 inflammasome activation via SIRT1

Peng Zou, Xiaoxiao Liu, Gang Li, Yangang Wang
Article Number: 191
Published online on: 05 May 2026

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Gut microbiota and its metabolites: Key factors of drug resistance in the treatment of advanced prostate cancer (Review)

Jingheng Song, Hongguo Cui, Peisen Yang, Yankai Xu, Yuanyuan Liu, Gang Zhang, Yangyang Liu, Aimin Tian, Jizhong Che, Hui Sun, Zhengchao Zhang
Article Number: 190
Published online on: 04 May 2026

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Cepharanthine inhibits lysosomes and induces apoptosis in triple‑negative breast cancer cells

Juan Li, Siqin Zhou, Yu Wang, Guanghan Ou, Danli Yang, Liwen Shen
Article Number: 189
Published online on: 04 May 2026

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Applications of humanized mice in Mycobacterium tuberculosis infections (Review)

Binghua Han, Fang Liu, Jinzhao Long, Jiongjiong Wang, Yange Cui, Haiyan Yang
Article Number: 188
Published online on: 04 May 2026

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Research progress on neutrophil extracellular traps in sepsis‑induced coagulopathy (Review)

Jiandong Hu, Mengli Jin, Zhihua Cao, Binbin Zheng, Yuan Zheng, Hao Shen
Article Number: 187
Published online on: 04 May 2026

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Multifaceted regulatory role of proline‑ and glutamine-rich splicing factor in tumors (Review)

Shilin Zhang, Zhenhua Li, Li Fu
Article Number: 186
Published online on: 04 May 2026

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Article Open Access

Effects of ALDH2 gene expression on the oxidative stress‑mediated NF‑κB/mTOR pathway in ketamine‑induced cystitis

Xiao Jian Xi, Yong Yao, Peng Gu, Min Hao Zhang
Article Number: 185
Published online on: 04 May 2026

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[Retracted] Rosiglitazone exerts neuroprotective effects via the suppression of neuronal autophagy and apoptosis in the cortex following traumatic brain injury

Junchao Yao, Kebin Zheng, Xiang Zhang
Article Number: 184
Published online on: 29 April 2026

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