|
1
|
Hepatocellular carcinoma. Nat Rev Dis
Primers. 2:160192016. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Gingold JA, Zhu D, Lee DF, Kaseb A and
Chen J: Genomic profiling and metabolic homeostasis in primary
liver cancers. Trends Mol Med. 24:395–411. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
McGuire S: World cancer report 2014.
Geneva, Switzerland: World health organization, international
agency for research on cancer, WHO press, 2015. Adv Nutr.
7:418–419. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Gholamreza K, Jadidi-Niaragh F, Jahromi
AS, Zandi K and Hojjat-Farsangi M: Mechanisms of tumor cell
resistance to the current targeted-therapy agents. Tumour Biol.
37:10021–10039. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Dong X and Mumper RJ: Nanomedicinal
strategies to treat multidrug-resistant tumors: Current progress.
Nanomedicine (Lond). 5:597–615. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Xie Y and Zhong DW: AEG-1 is associated
with hypoxia-induced hepatocellular carcinoma chemoresistance via
regulating PI3K/AKT/HIF-1alpha/MDR-1 pathway. EXCLI J. 15:745–757.
2016.PubMed/NCBI
|
|
7
|
Xiong H, Ni Z, He J, Jiang S, Li X, He J,
Gong W, Zheng L, Chen S, Li B, et al: LncRNA HULC triggers
autophagy via stabilizing Sirt1 and attenuates the chemosensitivity
of HCC cells. Oncogene. 36:3528–3540. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Gade TPF, Tucker E, Nakazawa MS, Hunt SJ,
Wong W, Krock B, Weber CN, Nadolski GJ, Clark TWI, Soulen MC, et
al: Ischemia induces quiescence and autophagy dependence in
hepatocellular carcinoma. Radiology. 283:702–710. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Siegel RL, Miller KD and Jemal A: Cancer
statistics, 2017. CA Cancer J Clin. 67:7–30. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Dong LQ, Shen BQ and Ma Y: Research
progress of hypoxia microenvironment in hepatocellular carcinoma.
Zhong Guo Pu Wai Ji Chu Yu Lin Chuang Za Zhi. 25:1254–1258.
2018.(In Chinese).
|
|
11
|
Moon HJ, Finney J, Ronnebaum T and Mure M:
Human lysyl oxidase-like 2. Bioorg Chem. 57:231–241. 2014.
View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Ferreira S, Saraiva N, Rijo P and
Fernandes AS: LOXL2 inhibitors and breast cancer progression.
Antioxidants (Basel). 10:3122021. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Philp CJ, Siebeke I, Clements D, Miller S,
Habgood A, John AE, Navaratnam V, Hubbard RB, Jenkins G and Johnson
SR: Extracellular matrix cross-linking enhances fibroblast growth
and protects against matrix proteolysis in lung fibrosis. Am J
Respir Cell Mol Biol. 58:594–603. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Galván JA, Zlobec I, Wartenberg M, Lugli
A, Gloor B, Perren A and Karamitopoulou E: Expression of E-cadherin
repressors SNAIL, ZEB1 and ZEB2 by tumour and stromal cells
influences tumour-budding phenotype and suggests heterogeneity of
stromal cells in pancreatic cancer. Br J Cancer. 112:1944–1950.
2015. View Article : Google Scholar
|
|
15
|
Gu C, Yang X and Huang L: Cistanches
herba: A neuropharmacology review. Front Pharmacol. 7:2892016.
View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Fu Z, Fan X, Wang X and Gao X: Cistanches
Herba: An overview of its chemistry, pharmacology, and
pharmacokinetics property. J Ethnopharmacol. 219:233–247. 2018.
View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Hu Q, You SP, Liu T, Wang B, Liu X and
Jiang Y: An investigation on the anti-liver cancer effect of
cistanche. Carcinog Teratog Mutagen. 30:194–199. 2018.
|
|
18
|
Mao J, Tian Y, Wang C, Jiang K, Li R, Yao
Y, Zhang R, Sun D, Liang R, Gao Z, et al: CBX2 regulates
proliferation and apoptosis via the phosphorylation of YAP in
hepatocellular carcinoma. J Cancer. 10:2706–2719. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Qin Y, Liu HJ, Li M, Zhai DH, Tang YH,
Yang L, Qiao KL, Yang JH, Zhong WL, Zhang Q, et al: Salidroside
improves the hypoxic tumor microenvironment and reverses the drug
resistance of platinum drugs via HIF-1α signaling pathway.
EBioMedicine. 38:25–36. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(-Delta Delta C(T)) method. Methods. 25:402–408. 2001.
View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Vaupel P: Tumor microenvironmental
physiology and its implications for radiation oncology. Semin
Radiat Oncol. 14:198–206. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Chen C and Lou T: Hypoxia inducible
factors in hepatocellular carcinoma. Oncotarget. 8:46691–46703.
2017. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Schwabe RF and Luedde T: Apoptosis and
necroptosis in the liver: A matter of life and death. Nat Rev
Gastroenterol Hepatol. 15:738–752. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Kanda T, Matsuoka S, Yamazaki M, Shibata
T, Nirei K, Takahashi H, Kaneko T, Fujisawa M, Higuchi T, Nakamura
H, et al: Apoptosis and non-alcoholic fatty liver diseases. World J
Gastroenterol. 24:2661–2672. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Pittala S, Krelin Y and Shoshan-Barmatz V:
Targeting liver cancer and associated pathologies in mice with a
mitochondrial VDAC1-based Peptide. Neoplasia. 20:594–609. 2018.
View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Jing ZT, Liu W, Xue CR, Wu SX, Chen WN,
Lin XJ and Lin X: AKT activator SC79 protects hepatocytes from
TNF-α-mediated apoptosis and alleviates d-Gal/LPS-induced liver
injury. Am J Physiol Gastrointest Liver Physiol. 316:G387–G396.
2019. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Zhu YJ, Zheng B, Wang HY and Chen L: New
knowledge of the mechanisms of sorafenib resistance in liver
cancer. Acta Pharmacol Sin. 38:614–622. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Wei R, Cao J and Yao S: Matrine promotes
liver cancer cell apoptosis by inhibiting mitophagy and
PINK1/Parkin pathways. Cell Stress Chaperones. 23:1295–1309. 2018.
View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Shen L and Zhang G, Lou Z, Xu G and Zhang
G: Cryptotanshinone enhances the effect of arsenic trioxide in
treating liver cancer cell by inducing apoptosis through
downregulating phosphorylated-STAT3 in vitro and in vivo. BMC
Complement Altern Med. 17:1062017. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Wu F, Zhang J, Liu Y, Zheng Y and Hu N:
HIF1α genetic variants and protein expressions determine the
response to platinum based chemotherapy and clinical outcome in
patients with advanced NSCLC. Cell Physiol Biochem. 32:1566–1576.
2013. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Heerboth S, Housman G, Leary M, Longacre
M, Byler S, Lapinska K, Willbanks A and Sarkar S: EMT and tumor
metastasis. Clin Transl Med. 4:62015. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Hapke RY and Haake SM: Hypoxia-induced
epithelial to mesenchymal transition in cancer. Cancer Lett.
487:10–20. 2020. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Zhao Z, Rahman MA, Chen ZG and Shin DM:
Multiple biological functions of Twist1 in various cancers.
Oncotarget. 8:20380–20393. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Goossens S, Vandamme N, Van Vlierberghe P
and Berx G: EMT transcription factors in cancer development
re-evaluated: Beyond EMT and MET. Biochim Biophys Acta Rev Cancer.
1868:584–591. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Shao B, Zhao X, Liu T, Zhang Y, Sun R,
Dong X, Liu F, Zhao N, Zhang D, Wu L, et al: LOXL2 promotes
vasculogenic mimicry and tumour aggressiveness in hepatocellular
carcinoma. J Cell Mol Med. 23:1363–1374. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Wu L, Zhang Y, Zhu Y, Cong Q, Xiang Y and
Fu L: The effect of LOXL2 in hepatocellular carcinoma. Mol Med Rep.
14:1923–1932. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Peng L, Ran YL, Hu H, Yu L, Liu Q, Zhou Z,
Sun YM, Sun LC, Pan J, Sun LX, et al: Secreted LOXL2 is a novel
therapeutic target that promotes gastric cancer metastasis via the
Src/FAK pathway. Carcinogenesis. 30:1660–1669. 2009. View Article : Google Scholar : PubMed/NCBI
|
