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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
July-2021 Volume 24 Issue 1

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Journal Metrics

Impact Factor: 3.5

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

CXCR3 alleviates renal ischemia‑reperfusion injury via increase of Tregs

Wenjing Xian, Jiali Wu, Qingshu Li, Xunsong Du, Na Wang, Daiyu Chen, Wuxi Gao, Jun Cao
Article Number: 541
Published online on: 28 May 2021

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circSAMD4A participates in the apoptosis and autophagy of dopaminergic neurons via the miR‑29c‑3p‑mediated AMPK/mTOR pathway in Parkinson's disease

Wensheng Wang, Rongxiang Lv, Jingjing Zhang, Yu Liu
Article Number: 540
Published online on: 27 May 2021

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Correction Open Access

[Corrigendum] NORAD regulates epithelial‑mesenchymal transition of non‑small cell lung cancer cells via miR‑422a

Zhikun Chen, Qin Che, Chunxue Xie
Article Number: 539
Published online on: 27 May 2021

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Article Open Access

Downregulation of miR‑483‑5p inhibits TGF‑β1‑induced EMT by targeting RhoGDI1 in pulmonary fibrosis

Guichuan Huang, Jing Zhang, Gang Qing, Daishun Liu, Xin Wang, Yi Chen, Yongchang Wu, Yishi Li, Shuliang Guo
Article Number: 538
Published online on: 26 May 2021

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Article Open Access

Ginkgolide B‑mediated therapeutic effects on perioperative neurocognitive dysfunction are associated with the inhibition of iNOS‑mediated production of NO

Ting Luo, Dandan Lin, Yanan Hao, Rong Shi, Changwei Wei, Wenzhen Shen, Anshi Wu, Peili Huang
Article Number: 537
Published online on: 26 May 2021

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Article Open Access

Low‑calorie sweetener D‑psicose promotes hydrogen peroxide‑mediated apoptosis in C2C12 myogenic cells favoring skeletal muscle cell injury

Zhen-Jie Wei, Lu Sun, Yu-Lin Li, Jibran Sualeh Muhammad, Ying Wang, Qian-Wen Feng, Yan-Zhuo Zhang, Hidekuni Inadera, Zheng-Guo Cui, Cheng-Ai Wu
Article Number: 536
Published online on: 26 May 2021

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Article Open Access

Tannic acid alleviates lipopolysaccharide‑induced H9C2 cell apoptosis by suppressing reactive oxygen species‑mediated endoplasmic reticulum stress

Yan-Ping Yang, Jie-Qiong Zhao, Hai-Bo Gao, Jin-Jing Li, Xiao-Li  Li, Xiao-Lin Niu, Yong-Hong Lei, Xue Li
Article Number: 535
Published online on: 26 May 2021

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Article Open Access

Ophiopogonin B induces reactive oxygen species‑dependent apoptosis through the Hippo pathway in nasopharyngeal carcinoma

Wenhui Dong, Qing Dong, Hairui Ding
Article Number: 534
Published online on: 26 May 2021

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Article Open Access

lncRNA TUG1 inhibits the cancer stem cell‑like properties of temozolomide‑resistant glioma cells by interacting with EZH2

Yiqiang Cao, Wenying Chai, Yonggang Wang, Dang Tang, Dongchuan Shao, Hai Song, Jiang Long
Article Number: 533
Published online on: 25 May 2021

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Article Open Access

Anti‑inflammatory effect of Chrysanthemum zawadskii, peppermint, Glycyrrhiza glabra herbal mixture in lipopolysaccharide‑stimulated RAW264.7 macrophages

Byoung Ok Cho, Jae Young Shin, Hyun Ju Kang, Ji Hyeon Park, Suping Hao, Feng Wang, Seon Il Jang
Article Number: 532
Published online on: 25 May 2021

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Article Open Access

Guan Xin Dan Shen formulation protects db/db mice against diabetic cardiomyopathy via activation of Nrf2 signaling

Bin Zhang, Chen-Yang Zhang, Xue-Lian Zhang, Gui-Bo Sun, Xiao-Bo Sun
Article Number: 531
Published online on: 25 May 2021

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Article Open Access

CDCA2 promotes tumorigenesis and induces radioresistance in oesophageal squamous cell carcinoma cells

Bing Xu, Hui Chen, Zhipeng Xu, Xijuan Yao, Xinchen Sun, Hongyan Cheng
Article Number: 530
Published online on: 25 May 2021

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Article Open Access

κ‑opioid receptor agonist, U50488H, inhibits pyroptosis through NLRP3 via the Ca2+/CaMKII/CREB signaling pathway and improves synaptic plasticity in APP/PS1 mice

Xiaofu Song, Zhiqiang Cui, Jiahuan He, Tuo Yang, Xiaohong Sun
Article Number: 529
Published online on: 25 May 2021

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Article Open Access

miR‑135a‑5p inhibits tumor invasion by targeting ANGPT2 in gallbladder cancer

Haiyan Diao, Xing Xu, Bin Zhao, Guanghua Yang
Article Number: 528
Published online on: 25 May 2021

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Article

MicroRNA‑421 attenuates macrophage‑mediated inflammation by inhibiting PDCD4 in vitro

Huifang Liu, Junzhi Sun, Li Gao, Lingling Fan, Dongmei Chen, Lifang Wu
Article Number: 527
Published online on: 25 May 2021

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Article Open Access

LDL‑induced NLRC3 inflammasome activation in cardiac fibroblasts contributes to cardiomyocytic dysfunction

Peng Wang, Wenbo Zhang, Zhen Feng, Jian Zhang, Ying Sun, Wei Zhang
Article Number: 526
Published online on: 25 May 2021

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Article Open Access

Endoplasmic reticulum stress promotes epithelial‑mesenchymal transition via the PERK signaling pathway in paraquat‑induced pulmonary fibrosis

Xiaoxiao Meng, Kan Liu, Hui Xie, Yong Zhu, Wei Jin, Jian Lu, Ruilan Wang
Article Number: 525
Published online on: 25 May 2021

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Article Open Access

Effects of Txk‑mediated activation of NF‑κB signaling pathway on neurological deficit and oxidative stress after ischemia‑reperfusion in rats

Qian-Lan Xu, Jie Wu
Article Number: 524
Published online on: 21 May 2021

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Article Open Access

Knockdown of GBAS regulates esophageal cancer cell viability and apoptosis

Jun Peng, Ke Ma, Hao Rong, Bo Xiao, Jiang Zhu, Jin-Tao He
Article Number: 523
Published online on: 21 May 2021

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Retraction Open Access

[Retracted] Decreased microRNA‑132 and its function in human non‑small cell lung cancer

Xiyu Liu, Song Yan, Changyan Pei, Youbin Cui
Article Number: 522
Published online on: 20 May 2021

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Article Open Access

Role of P2X7R in eosinophilic and non‑eosinophilic chronic rhinosinusitis with nasal polyps

Yan Wang, Shan Chen, Wenwen Wang, Jianjun Chen, Weijia Kong, Yanjun Wang
Article Number: 521
Published online on: 20 May 2021

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Article Open Access

Carbenoxolone has the potential to ameliorate acute incision pain in rats

Shuzhen Dong, Kai Zhang, Yisa Shi
Article Number: 520
Published online on: 18 May 2021

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Correction Open Access

[Corrigendum] miR‑126 overexpression attenuates oxygen‑glucose deprivation/reperfusion injury by inhibiting oxidative stress and inflammatory response via the activation of SIRT1/Nrf2 signaling pathway in human umbilical vein endothelial cells

Jixin Li, Caili Yang, Yan Wang
Article Number: 519
Published online on: 18 May 2021

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Article Open Access

Hydrogen sulfide attenuates renal I/R‑induced activation of the inflammatory response and apoptosis via regulating Nrf2‑mediated NLRP3 signaling pathway inhibition

Yonghong Su, Yaoqi Wang, Min Liu, Hongguang Chen
Article Number: 518
Published online on: 17 May 2021

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Article Open Access

Phenylethanol glycosides from Herba Cistanche improve the hypoxic tumor microenvironment and enhance the effects of oxaliplatin via the HIF‑1α signaling pathway

Limei Wen, Junping Hu, Jiawei Zhang, Jianhua Yang
Article Number: 517
Published online on: 17 May 2021

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Article Open Access

KIF4A knockdown suppresses ovarian cancer cell proliferation and induces apoptosis by downregulating BUB1 expression

Wumin Jin, Lianmin Ye
Article Number: 516
Published online on: 17 May 2021

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Article Open Access

Selective inhibition of JNK mitochondrial location is protective against seawater inhalation‑induced ALI/ARDS

Liyan Bo, Yanyan Li, Wei Liu, Faguang Jin, Congcong Li
Article Number: 515
Published online on: 14 May 2021

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Review

NLRP3 inflammasome in sepsis (Review)

Xueyan Shi, Sichuang Tan, Sipin Tan
Article Number: 514
Published online on: 13 May 2021

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Correction Open Access

[Corrigendum] Beneficial effects of sulfonamide‑based gallates on osteoblasts in vitro

Li Huang, Pan Jin, Xiao Lin, Cuiwu Lin, Li Zheng, Jinmin Zhao
Article Number: 513
Published online on: 13 May 2021

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Review

Clinical Genomic, phenotype and epigenetic insights into the pathology, autoimmunity and weight management of patients with Myasthenia Gravis (Review)

Rebecca Golfinopoulou, Louis Papageorgiou, Aspasia Efthimiadou, Flora Bacopoulou, George P. Chrousos, Elias Eliopoulos, Dimitrios Vlachakis
Article Number: 512
Published online on: 12 May 2021

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Article Open Access

Long non‑coding RNA‑DUXAP8 regulates TOP2A in the growth and metastasis of osteosarcoma via microRNA‑635

Ting Yang, Jian Ping Guo, Fan Li, Chao Xiu, Hua Wang, Xian Liang Duan
Article Number: 511
Published online on: 12 May 2021

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Article Open Access

lncRNA GAS5‑mediated miR‑23a‑3p promotes inflammation and cell apoptosis by targeting TLR4 in a cell model of sepsis

Zhenping Gao, Dan Huang
Article Number: 510
Published online on: 11 May 2021

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Article Open Access

3,4,5‑Trihydroxycinnamic acid exerts anti‑inflammatory effects on TNF‑α/IFN‑γ‑stimulated HaCaT cells

Ji-Won Park, Jae-Hoon Oh, Daseul Hwang, Seong-Man Kim, Jae-Hong Min, Ji-Yun Seo, Wanjoo Chun, Hee Jae Lee, Sei-Ryang Oh, Jae-Won Lee, Kyung-Seop Ahn
Article Number: 509
Published online on: 11 May 2021

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Article Open Access

LY‑294002 enhances the chemosensitivity of liver cancer to oxaliplatin by blocking the PI3K/AKT/HIF‑1α pathway

Ruyue Xu, Yinci Zhang, Amin Li, Yongfang Ma, Wenpeng Cai, Li  Song, Yinghai Xie, Shuping Zhou, Weiya Cao, Xiaolong Tang
Article Number: 508
Published online on: 11 May 2021

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Overexpression of hsa_circ_0001445 reverses oxLDL‑induced inhibition of HUVEC proliferation via SRSF1

Guiying Liang, Sihua Chen, Sha Xin, Liang Dong
Article Number: 507
Published online on: 10 May 2021

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Review Open Access

Regulation and mechanism of YAP/TAZ in the mechanical microenvironment of stem cells (Review) Erratum in /10.3892/mmr.2021.12265

Ying Li, Jinming Wang, Weiliang Zhong
Article Number: 506
Published online on: 10 May 2021

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Correction Open Access

[Corrigendum] TLR4 mediates inflammation and hepatic fibrosis induced by chronic intermittent hypoxia in rats

Zhi-Peng Lin, Hui-Li Lin, Xue-Ping Yu, Yi-Juan Zheng, Si-Yu Cheng
Article Number: 505
Published online on: 10 May 2021

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Correction Open Access

[Corrigendum] HK2 is associated with the Warburg effect and proliferation in liver cancer: Targets for effective therapy with glycyrrhizin

Zengpeng Sun, Zhiguo Tan, Chuang Peng, Weimin Yi
Article Number: 504
Published online on: 10 May 2021

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Article Open Access

lncRNA NEAT1 regulates gastric carcinoma cell proliferation, invasion and apoptosis via the miR‑500a‑3p/XBP‑1 axis

Yun Zhou, Zhenghong Sha, Yong Yang, Shuimei Wu, Hong Chen
Article Number: 503
Published online on: 09 May 2021

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Article Open Access

Silencing a disintegrin and metalloproteinase‑33 attenuates the proliferation of vascular smooth muscle cells via PI3K/AKT pathway: Implications in the pathogenesis of airway vascular remodeling

Fang Yan, Yanyan Hao, Xinji Gong, Hu Sun, Jianbing Ding, Jing Wang
Article Number: 502
Published online on: 09 May 2021

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Article Open Access

Polygonatum sibiricum F. Delaroche polysaccharide ameliorates HFD‑induced mouse obesity via regulation of lipid metabolism and inflammatory response

Bo Liu, Yuan Tang, Zhenyan Song, Jinwen Ge
Article Number: 501
Published online on: 09 May 2021

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Review Open Access

Oral peroxidases: From antimicrobial agents to ecological actors (Review)

Philippe Courtois
Article Number: 500
Published online on: 06 May 2021

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Article Open Access

Transforming growth factor‑β1 functions as a competitive endogenous RNA that ameliorates intracranial hemorrhage injury by sponging microRNA‑93‑5p

Han Wang, Xianming Cao, Xiaoqing Wen, Dongling Li, Yetong Ouyang, Bing Bao, Yuqin Zhong, Zhengfang Qin, Min Yin, Zhiying Chen, Xiaoping Yin
Article Number: 499
Published online on: 06 May 2021

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Article Open Access

Circulating microRNA‑135a‑3p in serum extracellular vesicles as a potential biological marker of non‑alcoholic fatty liver disease

Hemin Jiang, Yu Qian, Ziyang Shen, Yuwei Liu, Yunqiang He, Rui Gao, Min Shen, Shu Chen, Qi Fu, Tao Yang
Article Number: 498
Published online on: 06 May 2021

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Article Open Access

Downregulation of microRNA‑221 facilitates H1N1 influenza A virus replication through suppression of type‑IFN response by targeting the SOCS1/NF‑κB pathway

Nali Zhang, Yuan Ma, Yuheng Tian, Yafei Zhou, Yuhua Tang, Shaobo Hu
Article Number: 497
Published online on: 06 May 2021

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Article Open Access

Human epididymis protein 4 promotes P‑glycoprotein‑mediated chemoresistance in ovarian cancer cells through interactions with Annexin II

Qing Liu, Da-Wo Liu, Ming-Jun Zheng, Lu Deng, Hui-Min Wang, Shan Jin, Juan-Juan Liu, Ying-Ying Hao, Lian-Cheng Zhu, Bei Lin
Article Number: 496
Published online on: 05 May 2021

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Article Open Access

Rapamycin protects against aristolochic acid nephropathy in mice by potentiating mammalian target of rapamycin‑mediated autophagy

Fan Lin, Yunqi Liu, Lili Tang, Xiaohui Xu, Xueli Zhang, Yifan Song, Bicheng Chen, Yeping Ren, Xiangdong Yang
Article Number: 495
Published online on: 05 May 2021

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Case Report Open Access

Further phenotypic features and two novel POC1A variants in a patient with SOFT syndrome: A case report

Songting Li, Yan Zhong, Yongjia Yang, Siping He, Wenjuan He
Article Number: 494
Published online on: 05 May 2021

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Review Open Access

Inflammatory response in epilepsy is mediated by glial cell gap junction pathway (Review)

Guangliang Wang, Jiangtao Wang, Cuijuan Xin, Jinyu Xiao, Jianmin Liang, Xuemei Wu
Article Number: 493
Published online on: 05 May 2021

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Article Open Access

Electroacupuncture at GV20‑GB7 regulates mitophagy to protect against neurological deficits following intracerebral hemorrhage via inhibition of apoptosis Expression of Concern in /10.3892/mmr.2026.13870 Corrigendum in /10.3892/mmr.2026.13930

Ruiqiao Guan, Zhihao Li, Xiaohong Dai, Wei Zou, Xueping Yu, Hao Liu, Qiuxin Chen, Wei Teng, Peng Liu, Xiaoying Liu, Shanshan Dong
Article Number: 492
Published online on: 05 May 2021

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Review

Roles of Cl‑/HCO3‑ anion exchanger 2 in the physiology and pathophysiology of the digestive system (Review)

Hui Wang, Jiaxing An, Hai Jin, Suyu He, Chengcheng Liao, Juan Wang, Biguang Tuo
Article Number: 491
Published online on: 05 May 2021

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Retraction Open Access

[Retracted] In vitro antitumor activity of the ethyl acetate extract Potentilla chinensis in osteosarcoma cancer cells

Guang Wan, Jin-Gang Tao, Guo-Dong Wang, Shen-Peng Liu, Hong-Xing Zhao, Qiu-Dong Liang
Article Number: 490
Published online on: 05 May 2021

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Correction Open Access

[Corrigendum] Role of adenosine deaminase 2 gene variants in pediatric deficiency of adenosine deaminase 2: A structural biological approach

Maria I. Zervou, George N. Goulielmos, Michail Matalliotakis, Charoula Matalliotaki, Demetrios A. Spandidos, Elias Eliopoulos
Article Number: 489
Published online on: 05 May 2021

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Article

Ivermectin inhibits cell proliferation and the expression levels of type I collagen, α‑SMA and CCN2 in hypertrophic scar fibroblasts

Song Tian, Yongjun Zheng, Shichu Xiao, Pengfei Luo, Rongju Sun, Jun Liu, Zhaofan Xia
Article Number: 488
Published online on: 29 April 2021

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Article Open Access

Parthenolide plays a protective role in the liver of mice with metabolic dysfunction‑associated fatty liver disease through the activation of the HIPPO pathway

Weihong Wang, Yukai He, Qiuli Liu
Article Number: 487
Published online on: 29 April 2021

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Article Open Access

Pyropia yezoensis protein protects against TNF‑α‑induced myotube atrophy in C2C12 myotubes via the NF‑κB signaling pathway

Min-Kyeong Lee, Youn Hee Choi, Taek-Jeong Nam
Article Number: 486
Published online on: 28 April 2021

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Article Open Access

Non-toxic sulfur inhibits LPS-induced inflammation by regulating TLR-4 and JAK2/STAT3 through IL-6 signaling

Dong Young Kang, Nipin Sp, Eun Seong Jo, Alexis Rugamba, Hyoung Do Kim, Il Ho Kim, Jong-Chan Park, Se Won Bae, Kyoung-Jin Jang, Young Mok Yang
Article Number: 485
Published online on: 27 April 2021

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Article Open Access

Oleic acid induces A7r5 cell proliferation and migration associated with increased expression of HGF and p‑p38

Jingjing Li, Ting Chu, Maosheng Yang
Article Number: 484
Published online on: 27 April 2021

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Article Open Access

CDC20 promotes the progression of hepatocellular carcinoma by regulating epithelial‑mesenchymal transition

Gang Yang, Guan Wang, Yongfu Xiong, Ji Sun, Weinan Li, Tao Tang, Jingdong Li
Article Number: 483
Published online on: 27 April 2021

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Article Open Access

The natural product lapiferin inhibits cell proliferation and promotes cell apoptosis in gingival squamous cell carcinoma via P21 regulation

Lin Liu, Cheng Peng, Yan Ruan, Qian Zhang
Article Number: 482
Published online on: 26 April 2021

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Retraction Open Access

[Retracted] Antitumor‑ and apoptosis‑inducing effects of pomolic acid against SK‑MEL‑2 human malignant melanoma cells are mediated via inhibition of cell migration and sub‑G1 cell cycle arrest

Tian-Hang Li, Hong-Xia Yan
Article Number: 481
Published online on: 26 April 2021

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Journal Cover
July-2026 Volume 34 Issue 1

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Journal Metrics

Impact Factor: 3.5

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Regulatory mechanisms and therapeutic potential of N6-methyladenosine modification in retinal diseases (Review)

Wenyao Zhang, Jinying Chen, Jingxiang Zhong
Article Number: 213
Published online on: 29 May 2026

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Epigenetic orchestration of scar formation: Therapeutic potential of targeting DNA methylation and non‑coding RNAs in cutaneous fibrosis (Review)

Jinshun Li, Weiyun Liu, Jin Yang, Yanan Li
Article Number: 212
Published online on: 29 May 2026

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Elucidating the multitarget neuroprotective mechanisms of protocatechuic acid in neurological disorders (Review)

Xiaoyan Xue, Yongchang Lai, Shasha Song, Liping Wu, Lifang Wang
Article Number: 211
Published online on: 29 May 2026

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Retraction Open Access

[Retracted] Piperine depresses the migration progression via downregulating the Akt/mTOR/MMP‑9 signaling pathway in DU145 cells

Yuan Zeng, Ying Yang
Article Number: 210
Published online on: 27 May 2026

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FOSL2 drives transcriptional activation of super‑enhancer-regulated DYNC1H1 to promote hypoxia‑induced oral squamous cell carcinoma progression

Linyu Jin, Jing Zhang, Wenjing Wang, Nan Zhang, Yang Liu, Alin Tian, Weiwei Yin, Yongle Qiu
Article Number: 209
Published online on: 25 May 2026

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Targeting lipophagy in atherosclerosis: Molecular mechanisms, pathogenesis and therapeutic interventions (Review)

Songhua Nan, Chaojie Peng, Xue Meng, Jingnan Jia, Fangfang Zhao, Yinglin Cui
Article Number: 208
Published online on: 22 May 2026

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Mechanisms of pruritus and advances in traditional Chinese medicine therapy (Review)

Hailing Zhang, Yongji Li, Yuan Liu, Danyi Feng, Letao Zhao, Ran Chen, Xiwu Zhang, Jinjin Dou
Article Number: 207
Published online on: 22 May 2026

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Reprogramming of the hepatic ubiquitin‑immune axis: A unifying mechanism in liver disease progression (Review)

Yadi Ju, Xiaodan Chong, Weichen Ning, Yan Shi, Yangyang Li, Yihai Shi
Article Number: 206
Published online on: 22 May 2026

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Role of the PI3K/AKT signaling pathway in regulating gene expression in rheumatoid arthritis (Review)

Chengzhi Cong, Yuan Wang, Jian Liu, Chao Jin
Article Number: 205
Published online on: 21 May 2026

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Biomarkers of radioresistance in lung cancer: Current insights and future directions (Review)

Fatima Zohra Attouahri, Imane Chaoui, Abdelilah Laraqui, Mohamed Rida Tagajdid, Mohammed Oukabli, Mohammed El Marjany, Meriem Khyatti, Mohammed Attaleb, Mouna Ababou, Khalid Ennibi, Khaoula Errafii, Mohammed El Mzibri
Article Number: 204
Published online on: 21 May 2026

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Epigenetic research methods and animal models for intervertebral disc degeneration (Review)

Xinliang Cui, Li Zeng, Wei Zhang, Leimin Xi, Rui Wang, Diff Jia, Safa, Haoyu Feng, Huidong Jia
Article Number: 203
Published online on: 21 May 2026

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ZBTB16 upregulation maintains copper homeostasis to support esophageal tumor progression

Jingyi Wang, Bin Yang, Shengzu Peng, Bin Yang
Article Number: 202
Published online on: 21 May 2026

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Correction Open Access

[Corrigendum] MicroRNA‑1 promotes cartilage matrix synthesis and regulates chondrocyte differentiation via post‑​transcriptional suppression of Ihh expression  

Taoyu Chen, Xianda Che, Pengfei Han, Jiangong Lu, Chunfang Wang, Bin Liang, Ziqi Hou, Xiaochun Wei, Lei Wei, Pengcui Li
Article Number: 201
Published online on: 20 May 2026

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Estrogen deficiency as a common driver and integrative mechanism in osteoporosis‑osteoarthritis comorbidity (Review)

Jian Cheng, Xiaodong Wu, Lu Zhao, Shuai Jiang, Wenjie Zhao, Weishuai Zhang
Article Number: 200
Published online on: 20 May 2026

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Role of RNA 5‑methylcytosine modification in cancer: Insights from coding and non‑coding RNAs (Review)

Qin Jiang, Yi Gong, Mimi Zhai, Tenglong Tang, Sushun Liu
Article Number: 199
Published online on: 20 May 2026

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m6A modification in skeletal system diseases (Review)

Xi Xie, Chen Li, Haotian Zheng, Guang Gan, Xi Gao
Article Number: 198
Published online on: 19 May 2026

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Dynamic regulation of the ‘mitochondria‑immune axis’ in myocardial infarction: Molecular mechanisms driving macrophage polarization through energy metabolism disorders (Review)

Yu Zhang, Hao Feng, Qin Wu, Shuxian Yang, Yundong Jiang, Houping Xu, Li Dong, Xiaolin Li, Hui Chen, Gang Luo
Article Number: 197
Published online on: 19 May 2026

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[Retracted] Homeobox B9 facilitates hypertrophic scar formation via activating the mitogen‑activated protein kinase signaling pathway

Qun Xie, Dandan Liu, Mosheng Yu, Xiaowei Wu, Yueqiang Zhao, Qiang Hu, Qi Wang
Article Number: 196
Published online on: 18 May 2026

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Polysaccharides: Natural candidates for targeting immunometabolic regulation in hepatocellular carcinoma (Review)

Changmei Wu, Jinjin Dou, Xiwu Zhang
Article Number: 195
Published online on: 18 May 2026

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Article Open Access

NF‑κB signaling drives Th17‑mediated lacrimal gland injury and tear dysfunction in a murine model of primary Sjögren's syndrome

Jiajun Xie, Huina Zhang, Wenyue Shen, Juan Ye
Article Number: 194
Published online on: 18 May 2026

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POSTN(+) fibroblasts and SPP1(+) macrophages in scar formation: A review of mechanisms and therapeutic targets (Review)

Haotian Wu, Xianglin Dong
Article Number: 193
Published online on: 15 May 2026

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Emerging role of DYRK1A as a target in cardiovascular diseases (Review)

Liqing Yu, Qionghong Cheng, Jun Wu
Article Number: 192
Published online on: 15 May 2026

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Retraction Open Access

[Retracted] Resveratrol pretreatment attenuates traumatic brain injury in rats by suppressing NLRP3 inflammasome activation via SIRT1

Peng Zou, Xiaoxiao Liu, Gang Li, Yangang Wang
Article Number: 191
Published online on: 05 May 2026

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Gut microbiota and its metabolites: Key factors of drug resistance in the treatment of advanced prostate cancer (Review)

Jingheng Song, Hongguo Cui, Peisen Yang, Yankai Xu, Yuanyuan Liu, Gang Zhang, Yangyang Liu, Aimin Tian, Jizhong Che, Hui Sun, Zhengchao Zhang
Article Number: 190
Published online on: 04 May 2026

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Cepharanthine inhibits lysosomes and induces apoptosis in triple‑negative breast cancer cells

Juan Li, Siqin Zhou, Yu Wang, Guanghan Ou, Danli Yang, Liwen Shen
Article Number: 189
Published online on: 04 May 2026

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Applications of humanized mice in Mycobacterium tuberculosis infections (Review)

Binghua Han, Fang Liu, Jinzhao Long, Jiongjiong Wang, Yange Cui, Haiyan Yang
Article Number: 188
Published online on: 04 May 2026

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Research progress on neutrophil extracellular traps in sepsis‑induced coagulopathy (Review)

Jiandong Hu, Mengli Jin, Zhihua Cao, Binbin Zheng, Yuan Zheng, Hao Shen
Article Number: 187
Published online on: 04 May 2026

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Multifaceted regulatory role of proline‑ and glutamine-rich splicing factor in tumors (Review)

Shilin Zhang, Zhenhua Li, Li Fu
Article Number: 186
Published online on: 04 May 2026

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Effects of ALDH2 gene expression on the oxidative stress‑mediated NF‑κB/mTOR pathway in ketamine‑induced cystitis

Xiao Jian Xi, Yong Yao, Peng Gu, Min Hao Zhang
Article Number: 185
Published online on: 04 May 2026

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[Retracted] Rosiglitazone exerts neuroprotective effects via the suppression of neuronal autophagy and apoptosis in the cortex following traumatic brain injury

Junchao Yao, Kebin Zheng, Xiang Zhang
Article Number: 184
Published online on: 29 April 2026

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August-2026 Volume 34 Issue 2

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Impact Factor: 3.5

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

Growth pattern and molecular biological analysis of primary meningioma cell cultures under different conditions

Stefan Linsler, Anna-Lena Moroldo, Walter Schulz‑schaeffer, Ralf Ketter, Joachim Oertel, Steffi Urbschat
Article Number: 228
Published online on: 12 June 2026

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Melatonin alleviates mitochondrial damage by regulating SIRT3‑mediated mitochondrial dynamics in granulosa cells under PCOS‑like conditions

Congcong Xie, Zehao Liu, Tong Chen, Hui Lu, Xiujia Zhang, Wenbo Yu, Jiaxin Zhang, Dandan Shang, Xueying Wang
Article Number: 227
Published online on: 11 June 2026

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Strontium‑based metal‑organic framework/alendronate‑silk fibroin hydrogels promote tendon‑bone interface healing

Tao Yang, Hanji Zhang, Mingjun Li, Yiming Ren, Yunbo Sun, Weiyu Hou, Mengqiang Tian
Article Number: 226
Published online on: 11 June 2026

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[Retracted] Tripterygium glycoside suppresses epithelial‑to‑­­ mesenchymal transition of diabetic kidney disease podocytes by targeting autophagy through the mTOR/Twist1 pathway

Mei Tao, Danna Zheng, Xudong Liang, Diandian Wu, Kang Hu, Juan Jin, Qiang He
Article Number: 225
Published online on: 08 June 2026

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Gut microbiota‑derived metabolites in cardiovascular disease: Focus on trimethylamine N‑oxide, short‑chain fatty acids and bile acids (Review)

Meizhu Gao, Zhenming Hao, Yiling Li, Weixue Liu, Fubao Zhang
Article Number: 224
Published online on: 08 June 2026

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Fucoxanthin alleviates chondrocyte inflammation and osteoarthritis by modulating the JAK2/STAT3 signaling pathway

Miradj Siddick Adam, Huangming Zhuang, Xunshan Ren, Yuelong Zhang, Panghu Zhou
Article Number: 223
Published online on: 08 June 2026

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Prediction of molecular targets for zedoary turmeric oil in inhibiting proliferation and inducing apoptosis in non‑small cell lung cancer

Huaiyong Li, Lili Liu, Qingzhu Yang, Yao Li, Yongli Song, Jing Jiang, Zhenzhong Wu, Weiwei Zhang, Baisong Lou
Article Number: 222
Published online on: 08 June 2026

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Molecular mechanisms of iron metabolism and ferroptosis in cardiovascular diseases and intervention strategies targeting natural products (Review)

Liangqing Ge, Tianqing Zhang, Jiangbiao Yu, Sijie Xiao, Yu Zhou, Li Luo
Article Number: 221
Published online on: 05 June 2026

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[Corrigendum] Electroacupuncture at GV20‑GB7 regulates mitophagy to protect against neurological deficits following intracerebral hemorrhage via inhibition of apoptosis

Ruiqiao Guan, Zhihao Li, Xiaohong Dai, Wei Zou, Xueping Yu, Hao Liu, Qiuxin Chen, Wei Teng, Peng Liu, Xiaoying Liu, Shanshan Dong
Article Number: 220
Published online on: 03 June 2026

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LINC01117 promotes the malignant proliferation of lung adenocarcinoma by increasing HOXD8 mRNA stability

Lizhong Zeng, Jie Shi, Cai Zhang, Yujiao Dong, Yang Chen, Qiuhong Zhang, Long Zhang, Shuanying Yang
Article Number: 219
Published online on: 03 June 2026

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Targeting regulatory T cells in the prostate cancer microenvironment: From mechanisms to therapeutics (Review)

Hua Luo
Article Number: 218
Published online on: 03 June 2026

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Dapagliflozin alleviates heart failure with preserved ejection fraction potentially by regulating the AIM2/caspase‑1/GSDMD pathway and attenuating pyroptosis

Sailiang Ding, Hao Yang, Ting Lu, Yibin Luo, Liang Xu, Xianghui Zeng
Article Number: 217
Published online on: 03 June 2026

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Retraction Open Access

[Retracted] Carnosic acid alleviates brain injury through NF‑κB‑regulated inflammation and Caspase‑3‑associated apoptosis in high fat‑induced mouse models

Yong Liu, Yan Zhang, Ming Hu, Yu-Hu Li, Xing-Hua Cao
Article Number: 216
Published online on: 02 June 2026

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SIRT1/AMPK/PGC1α pathway in ischemic stroke: Elucidating neuroprotective strategies (Review)

Irum Naz Abbasi, Nashwa Amin, Qiaolu Xu, Azhar Badry Hussain, Fei Wu, Xia Yuan, Yang Yang, Suhong Ye, Marong Fang, Yihua Jiang
Article Number: 215
Published online on: 02 June 2026

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Beyond the primary site: Molecular insights and clinical implications of cancer metastatic overlap between lung and urological organ cancers (Review)

Yinhuan Wang, Jiefang Guan
Article Number: 214
Published online on: 29 May 2026

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