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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
July-2021 Volume 24 Issue 1

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

CXCR3 alleviates renal ischemia‑reperfusion injury via increase of Tregs

Wenjing Xian, Jiali Wu, Qingshu Li, Xunsong Du, Na Wang, Daiyu Chen, Wuxi Gao, Jun Cao
Article Number: 541
Published online on: 28 May 2021

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circSAMD4A participates in the apoptosis and autophagy of dopaminergic neurons via the miR‑29c‑3p‑mediated AMPK/mTOR pathway in Parkinson's disease

Wensheng Wang, Rongxiang Lv, Jingjing Zhang, Yu Liu
Article Number: 540
Published online on: 27 May 2021

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Correction Open Access

[Corrigendum] NORAD regulates epithelial‑mesenchymal transition of non‑small cell lung cancer cells via miR‑422a

Zhikun Chen, Qin Che, Chunxue Xie
Article Number: 539
Published online on: 27 May 2021

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Article Open Access

Downregulation of miR‑483‑5p inhibits TGF‑β1‑induced EMT by targeting RhoGDI1 in pulmonary fibrosis

Guichuan Huang, Jing Zhang, Gang Qing, Daishun Liu, Xin Wang, Yi Chen, Yongchang Wu, Yishi Li, Shuliang Guo
Article Number: 538
Published online on: 26 May 2021

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Article Open Access

Ginkgolide B‑mediated therapeutic effects on perioperative neurocognitive dysfunction are associated with the inhibition of iNOS‑mediated production of NO

Ting Luo, Dandan Lin, Yanan Hao, Rong Shi, Changwei Wei, Wenzhen Shen, Anshi Wu, Peili Huang
Article Number: 537
Published online on: 26 May 2021

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Article Open Access

Low‑calorie sweetener D‑psicose promotes hydrogen peroxide‑mediated apoptosis in C2C12 myogenic cells favoring skeletal muscle cell injury

Zhen-Jie Wei, Lu Sun, Yu-Lin Li, Jibran Sualeh Muhammad, Ying Wang, Qian-Wen Feng, Yan-Zhuo Zhang, Hidekuni Inadera, Zheng-Guo Cui, Cheng-Ai Wu
Article Number: 536
Published online on: 26 May 2021

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Article Open Access

Tannic acid alleviates lipopolysaccharide‑induced H9C2 cell apoptosis by suppressing reactive oxygen species‑mediated endoplasmic reticulum stress

Yan-Ping Yang, Jie-Qiong Zhao, Hai-Bo Gao, Jin-Jing Li, Xiao-Li  Li, Xiao-Lin Niu, Yong-Hong Lei, Xue Li
Article Number: 535
Published online on: 26 May 2021

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Article Open Access

Ophiopogonin B induces reactive oxygen species‑dependent apoptosis through the Hippo pathway in nasopharyngeal carcinoma

Wenhui Dong, Qing Dong, Hairui Ding
Article Number: 534
Published online on: 26 May 2021

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Article Open Access

lncRNA TUG1 inhibits the cancer stem cell‑like properties of temozolomide‑resistant glioma cells by interacting with EZH2

Yiqiang Cao, Wenying Chai, Yonggang Wang, Dang Tang, Dongchuan Shao, Hai Song, Jiang Long
Article Number: 533
Published online on: 25 May 2021

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Article Open Access

Anti‑inflammatory effect of Chrysanthemum zawadskii, peppermint, Glycyrrhiza glabra herbal mixture in lipopolysaccharide‑stimulated RAW264.7 macrophages

Byoung Ok Cho, Jae Young Shin, Hyun Ju Kang, Ji Hyeon Park, Suping Hao, Feng Wang, Seon Il Jang
Article Number: 532
Published online on: 25 May 2021

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Article Open Access

Guan Xin Dan Shen formulation protects db/db mice against diabetic cardiomyopathy via activation of Nrf2 signaling

Bin Zhang, Chen-Yang Zhang, Xue-Lian Zhang, Gui-Bo Sun, Xiao-Bo Sun
Article Number: 531
Published online on: 25 May 2021

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Article Open Access

CDCA2 promotes tumorigenesis and induces radioresistance in oesophageal squamous cell carcinoma cells

Bing Xu, Hui Chen, Zhipeng Xu, Xijuan Yao, Xinchen Sun, Hongyan Cheng
Article Number: 530
Published online on: 25 May 2021

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Article Open Access

κ‑opioid receptor agonist, U50488H, inhibits pyroptosis through NLRP3 via the Ca2+/CaMKII/CREB signaling pathway and improves synaptic plasticity in APP/PS1 mice

Xiaofu Song, Zhiqiang Cui, Jiahuan He, Tuo Yang, Xiaohong Sun
Article Number: 529
Published online on: 25 May 2021

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Article Open Access

miR‑135a‑5p inhibits tumor invasion by targeting ANGPT2 in gallbladder cancer

Haiyan Diao, Xing Xu, Bin Zhao, Guanghua Yang
Article Number: 528
Published online on: 25 May 2021

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Article

MicroRNA‑421 attenuates macrophage‑mediated inflammation by inhibiting PDCD4 in vitro

Huifang Liu, Junzhi Sun, Li Gao, Lingling Fan, Dongmei Chen, Lifang Wu
Article Number: 527
Published online on: 25 May 2021

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Article Open Access

LDL‑induced NLRC3 inflammasome activation in cardiac fibroblasts contributes to cardiomyocytic dysfunction

Peng Wang, Wenbo Zhang, Zhen Feng, Jian Zhang, Ying Sun, Wei Zhang
Article Number: 526
Published online on: 25 May 2021

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Article Open Access

Endoplasmic reticulum stress promotes epithelial‑mesenchymal transition via the PERK signaling pathway in paraquat‑induced pulmonary fibrosis

Xiaoxiao Meng, Kan Liu, Hui Xie, Yong Zhu, Wei Jin, Jian Lu, Ruilan Wang
Article Number: 525
Published online on: 25 May 2021

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Article Open Access

Effects of Txk‑mediated activation of NF‑κB signaling pathway on neurological deficit and oxidative stress after ischemia‑reperfusion in rats

Qian-Lan Xu, Jie Wu
Article Number: 524
Published online on: 21 May 2021

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Article Open Access

Knockdown of GBAS regulates esophageal cancer cell viability and apoptosis

Jun Peng, Ke Ma, Hao Rong, Bo Xiao, Jiang Zhu, Jin-Tao He
Article Number: 523
Published online on: 21 May 2021

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Retraction Open Access

[Retracted] Decreased microRNA‑132 and its function in human non‑small cell lung cancer

Xiyu Liu, Song Yan, Changyan Pei, Youbin Cui
Article Number: 522
Published online on: 20 May 2021

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Article Open Access

Role of P2X7R in eosinophilic and non‑eosinophilic chronic rhinosinusitis with nasal polyps

Yan Wang, Shan Chen, Wenwen Wang, Jianjun Chen, Weijia Kong, Yanjun Wang
Article Number: 521
Published online on: 20 May 2021

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Article Open Access

Carbenoxolone has the potential to ameliorate acute incision pain in rats

Shuzhen Dong, Kai Zhang, Yisa Shi
Article Number: 520
Published online on: 18 May 2021

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Correction Open Access

[Corrigendum] miR‑126 overexpression attenuates oxygen‑glucose deprivation/reperfusion injury by inhibiting oxidative stress and inflammatory response via the activation of SIRT1/Nrf2 signaling pathway in human umbilical vein endothelial cells

Jixin Li, Caili Yang, Yan Wang
Article Number: 519
Published online on: 18 May 2021

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Article Open Access

Hydrogen sulfide attenuates renal I/R‑induced activation of the inflammatory response and apoptosis via regulating Nrf2‑mediated NLRP3 signaling pathway inhibition

Yonghong Su, Yaoqi Wang, Min Liu, Hongguang Chen
Article Number: 518
Published online on: 17 May 2021

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Phenylethanol glycosides from Herba Cistanche improve the hypoxic tumor microenvironment and enhance the effects of oxaliplatin via the HIF‑1α signaling pathway

Limei Wen, Junping Hu, Jiawei Zhang, Jianhua Yang
Article Number: 517
Published online on: 17 May 2021

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Article Open Access

KIF4A knockdown suppresses ovarian cancer cell proliferation and induces apoptosis by downregulating BUB1 expression

Wumin Jin, Lianmin Ye
Article Number: 516
Published online on: 17 May 2021

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Article Open Access

Selective inhibition of JNK mitochondrial location is protective against seawater inhalation‑induced ALI/ARDS

Liyan Bo, Yanyan Li, Wei Liu, Faguang Jin, Congcong Li
Article Number: 515
Published online on: 14 May 2021

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Review

NLRP3 inflammasome in sepsis (Review)

Xueyan Shi, Sichuang Tan, Sipin Tan
Article Number: 514
Published online on: 13 May 2021

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Correction Open Access

[Corrigendum] Beneficial effects of sulfonamide‑based gallates on osteoblasts in vitro

Li Huang, Pan Jin, Xiao Lin, Cuiwu Lin, Li Zheng, Jinmin Zhao
Article Number: 513
Published online on: 13 May 2021

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Review

Clinical Genomic, phenotype and epigenetic insights into the pathology, autoimmunity and weight management of patients with Myasthenia Gravis (Review)

Rebecca Golfinopoulou, Louis Papageorgiou, Aspasia Efthimiadou, Flora Bacopoulou, George P. Chrousos, Elias Eliopoulos, Dimitrios Vlachakis
Article Number: 512
Published online on: 12 May 2021

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Article Open Access

Long non‑coding RNA‑DUXAP8 regulates TOP2A in the growth and metastasis of osteosarcoma via microRNA‑635

Ting Yang, Jian Ping Guo, Fan Li, Chao Xiu, Hua Wang, Xian Liang Duan
Article Number: 511
Published online on: 12 May 2021

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Article Open Access

lncRNA GAS5‑mediated miR‑23a‑3p promotes inflammation and cell apoptosis by targeting TLR4 in a cell model of sepsis

Zhenping Gao, Dan Huang
Article Number: 510
Published online on: 11 May 2021

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3,4,5‑Trihydroxycinnamic acid exerts anti‑inflammatory effects on TNF‑α/IFN‑γ‑stimulated HaCaT cells

Ji-Won Park, Jae-Hoon Oh, Daseul Hwang, Seong-Man Kim, Jae-Hong Min, Ji-Yun Seo, Wanjoo Chun, Hee Jae Lee, Sei-Ryang Oh, Jae-Won Lee, Kyung-Seop Ahn
Article Number: 509
Published online on: 11 May 2021

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Article Open Access

LY‑294002 enhances the chemosensitivity of liver cancer to oxaliplatin by blocking the PI3K/AKT/HIF‑1α pathway

Ruyue Xu, Yinci Zhang, Amin Li, Yongfang Ma, Wenpeng Cai, Li  Song, Yinghai Xie, Shuping Zhou, Weiya Cao, Xiaolong Tang
Article Number: 508
Published online on: 11 May 2021

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Overexpression of hsa_circ_0001445 reverses oxLDL‑induced inhibition of HUVEC proliferation via SRSF1

Guiying Liang, Sihua Chen, Sha Xin, Liang Dong
Article Number: 507
Published online on: 10 May 2021

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Review Open Access

Regulation and mechanism of YAP/TAZ in the mechanical microenvironment of stem cells (Review) Erratum in /10.3892/mmr.2021.12265

Ying Li, Jinming Wang, Weiliang Zhong
Article Number: 506
Published online on: 10 May 2021

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Correction Open Access

[Corrigendum] TLR4 mediates inflammation and hepatic fibrosis induced by chronic intermittent hypoxia in rats

Zhi-Peng Lin, Hui-Li Lin, Xue-Ping Yu, Yi-Juan Zheng, Si-Yu Cheng
Article Number: 505
Published online on: 10 May 2021

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Correction Open Access

[Corrigendum] HK2 is associated with the Warburg effect and proliferation in liver cancer: Targets for effective therapy with glycyrrhizin

Zengpeng Sun, Zhiguo Tan, Chuang Peng, Weimin Yi
Article Number: 504
Published online on: 10 May 2021

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lncRNA NEAT1 regulates gastric carcinoma cell proliferation, invasion and apoptosis via the miR‑500a‑3p/XBP‑1 axis

Yun Zhou, Zhenghong Sha, Yong Yang, Shuimei Wu, Hong Chen
Article Number: 503
Published online on: 09 May 2021

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Article Open Access

Silencing a disintegrin and metalloproteinase‑33 attenuates the proliferation of vascular smooth muscle cells via PI3K/AKT pathway: Implications in the pathogenesis of airway vascular remodeling

Fang Yan, Yanyan Hao, Xinji Gong, Hu Sun, Jianbing Ding, Jing Wang
Article Number: 502
Published online on: 09 May 2021

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Article Open Access

Polygonatum sibiricum F. Delaroche polysaccharide ameliorates HFD‑induced mouse obesity via regulation of lipid metabolism and inflammatory response

Bo Liu, Yuan Tang, Zhenyan Song, Jinwen Ge
Article Number: 501
Published online on: 09 May 2021

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Review Open Access

Oral peroxidases: From antimicrobial agents to ecological actors (Review)

Philippe Courtois
Article Number: 500
Published online on: 06 May 2021

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Article Open Access

Transforming growth factor‑β1 functions as a competitive endogenous RNA that ameliorates intracranial hemorrhage injury by sponging microRNA‑93‑5p

Han Wang, Xianming Cao, Xiaoqing Wen, Dongling Li, Yetong Ouyang, Bing Bao, Yuqin Zhong, Zhengfang Qin, Min Yin, Zhiying Chen, Xiaoping Yin
Article Number: 499
Published online on: 06 May 2021

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Article Open Access

Circulating microRNA‑135a‑3p in serum extracellular vesicles as a potential biological marker of non‑alcoholic fatty liver disease

Hemin Jiang, Yu Qian, Ziyang Shen, Yuwei Liu, Yunqiang He, Rui Gao, Min Shen, Shu Chen, Qi Fu, Tao Yang
Article Number: 498
Published online on: 06 May 2021

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Article Open Access

Downregulation of microRNA‑221 facilitates H1N1 influenza A virus replication through suppression of type‑IFN response by targeting the SOCS1/NF‑κB pathway

Nali Zhang, Yuan Ma, Yuheng Tian, Yafei Zhou, Yuhua Tang, Shaobo Hu
Article Number: 497
Published online on: 06 May 2021

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Article Open Access

Human epididymis protein 4 promotes P‑glycoprotein‑mediated chemoresistance in ovarian cancer cells through interactions with Annexin II

Qing Liu, Da-Wo Liu, Ming-Jun Zheng, Lu Deng, Hui-Min Wang, Shan Jin, Juan-Juan Liu, Ying-Ying Hao, Lian-Cheng Zhu, Bei Lin
Article Number: 496
Published online on: 05 May 2021

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Article Open Access

Rapamycin protects against aristolochic acid nephropathy in mice by potentiating mammalian target of rapamycin‑mediated autophagy

Fan Lin, Yunqi Liu, Lili Tang, Xiaohui Xu, Xueli Zhang, Yifan Song, Bicheng Chen, Yeping Ren, Xiangdong Yang
Article Number: 495
Published online on: 05 May 2021

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Case Report Open Access

Further phenotypic features and two novel POC1A variants in a patient with SOFT syndrome: A case report

Songting Li, Yan Zhong, Yongjia Yang, Siping He, Wenjuan He
Article Number: 494
Published online on: 05 May 2021

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Review Open Access

Inflammatory response in epilepsy is mediated by glial cell gap junction pathway (Review)

Guangliang Wang, Jiangtao Wang, Cuijuan Xin, Jinyu Xiao, Jianmin Liang, Xuemei Wu
Article Number: 493
Published online on: 05 May 2021

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Article Open Access

Electroacupuncture at GV20‑GB7 regulates mitophagy to protect against neurological deficits following intracerebral hemorrhage via inhibition of apoptosis

Ruiqiao Guan, Zhihao Li, Xiaohong Dai, Wei Zou, Xueping Yu, Hao Liu, Qiuxin Chen, Wei Teng, Peng Liu, Xiaoying Liu, Shanshan Dong
Article Number: 492
Published online on: 05 May 2021

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Review

Roles of Cl‑/HCO3‑ anion exchanger 2 in the physiology and pathophysiology of the digestive system (Review)

Hui Wang, Jiaxing An, Hai Jin, Suyu He, Chengcheng Liao, Juan Wang, Biguang Tuo
Article Number: 491
Published online on: 05 May 2021

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Retraction Open Access

[Retracted] In vitro antitumor activity of the ethyl acetate extract Potentilla chinensis in osteosarcoma cancer cells

Guang Wan, Jin-Gang Tao, Guo-Dong Wang, Shen-Peng Liu, Hong-Xing Zhao, Qiu-Dong Liang
Article Number: 490
Published online on: 05 May 2021

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Correction Open Access

[Corrigendum] Role of adenosine deaminase 2 gene variants in pediatric deficiency of adenosine deaminase 2: A structural biological approach

Maria I. Zervou, George N. Goulielmos, Michail Matalliotakis, Charoula Matalliotaki, Demetrios A. Spandidos, Elias Eliopoulos
Article Number: 489
Published online on: 05 May 2021

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Article

Ivermectin inhibits cell proliferation and the expression levels of type I collagen, α‑SMA and CCN2 in hypertrophic scar fibroblasts

Song Tian, Yongjun Zheng, Shichu Xiao, Pengfei Luo, Rongju Sun, Jun Liu, Zhaofan Xia
Article Number: 488
Published online on: 29 April 2021

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Article Open Access

Parthenolide plays a protective role in the liver of mice with metabolic dysfunction‑associated fatty liver disease through the activation of the HIPPO pathway

Weihong Wang, Yukai He, Qiuli Liu
Article Number: 487
Published online on: 29 April 2021

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Article Open Access

Pyropia yezoensis protein protects against TNF‑α‑induced myotube atrophy in C2C12 myotubes via the NF‑κB signaling pathway

Min-Kyeong Lee, Youn Hee Choi, Taek-Jeong Nam
Article Number: 486
Published online on: 28 April 2021

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Article Open Access

Non-toxic sulfur inhibits LPS-induced inflammation by regulating TLR-4 and JAK2/STAT3 through IL-6 signaling

Dong Young Kang, Nipin Sp, Eun Seong Jo, Alexis Rugamba, Hyoung Do Kim, Il Ho Kim, Jong-Chan Park, Se Won Bae, Kyoung-Jin Jang, Young Mok Yang
Article Number: 485
Published online on: 27 April 2021

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Article Open Access

Oleic acid induces A7r5 cell proliferation and migration associated with increased expression of HGF and p‑p38

Jingjing Li, Ting Chu, Maosheng Yang
Article Number: 484
Published online on: 27 April 2021

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Article Open Access

CDC20 promotes the progression of hepatocellular carcinoma by regulating epithelial‑mesenchymal transition

Gang Yang, Guan Wang, Yongfu Xiong, Ji Sun, Weinan Li, Tao Tang, Jingdong Li
Article Number: 483
Published online on: 27 April 2021

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Article Open Access

The natural product lapiferin inhibits cell proliferation and promotes cell apoptosis in gingival squamous cell carcinoma via P21 regulation

Lin Liu, Cheng Peng, Yan Ruan, Qian Zhang
Article Number: 482
Published online on: 26 April 2021

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Retraction Open Access

[Retracted] Antitumor‑ and apoptosis‑inducing effects of pomolic acid against SK‑MEL‑2 human malignant melanoma cells are mediated via inhibition of cell migration and sub‑G1 cell cycle arrest

Tian-Hang Li, Hong-Xia Yan
Article Number: 481
Published online on: 26 April 2021

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Journal Cover
February-2026 Volume 33 Issue 2

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

ISX promotes tumor migration and invasion in lung cancer by upregulating COL1A1 in vitro

Yihe Ma, Ye Chen, Yuhui Liang, Yun Huang, Miao Gong, Lifeng Tian, Xiaojun Xiao, Jingyan Liu, Qinmiao Huang
Article Number: 77
Published online on: 31 December 2025

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Role and mechanism of miR‑222‑5p in endothelial cell apoptosis

Shimeng Wang, Boxin Zhao, Ying Cui, Lin Gui, Jingyao Fan, Lijuan Huang
Article Number: 76
Published online on: 31 December 2025

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Expression of Concern Open Access

[Expression of Concern] MicroRNA-29c inhibits proliferation and promotes apoptosis in non-small cell lung cancer cells by targeting VEGFA

Shijuan Zhan, Chunfeng Wang, Fangqing Yin
Article Number: 75
Published online on: 22 December 2025

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Melatonin induces autophagy in neuroblastoma by alleviating Pak2‑mediated endoplasmic reticulum stress

Qian-Qi Qiu, Na Zhang, Ying-Yi Xu, Jing-Wen Qin, Gao-Feng Yu, Xing-Rong Song
Article Number: 74
Published online on: 22 December 2025

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ST3Gal1 modulates intestinal barrier function and impacts human ulcerative colitis

Yin Tian, Yun Liu, Yangyang Shang, Lijian Ran, Li Liu, Rongquan Wang, Jun Ye
Article Number: 73
Published online on: 18 December 2025

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Mechanistic study of miR‑369‑3p in regulating the Wnt/β‑catenin signaling pathway via targeting SPTBN1 in inflammatory response and bone destruction of rheumatoid arthritis

Aihong Wu, Yuan Wang, Feifei Liu, Zhoufang Cao, Shuhui Du, Mengyu Sun
Article Number: 72
Published online on: 18 December 2025

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CACNB1 alleviates mepivacaine‑induced myocardial ischemia/reperfusion injury by promoting Nrf2 nuclear translocation

Qingbo Shao, Ji Zhang, Huaying Wang
Article Number: 71
Published online on: 17 December 2025

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Expression of Concern Open Access

[Expression of Concern] Effects of cullin 4B on the proliferation and invasion of human gastric cancer cells

Feng He, Xiu-Mei Cheng, Wen-Long Gu
Article Number: 70
Published online on: 17 December 2025

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Aggravated effects of human parvovirus B19 NS1 protein on bleomycin‑induced pulmonary fibrosis

Tsai-Ching Hsu, Chih-Chen Tzang, Chia-Wei Kuo, Zhi-Han Wen, Der-Yuan Chen, Bor-Show Tzang
Article Number: 69
Published online on: 16 December 2025

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Review Open Access

Advances regarding the mechanism of endoplasmic reticulum stress in diabetic kidney disease and pharmacological interventions (Review)

Pai Zhang, Yabin Cui, Chunyan Liu, Chengji Cui, Shoulin Zhang, Yue Zhang, Fan Li
Article Number: 68
Published online on: 16 December 2025

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Retraction Open Access

[Retracted] N‑Myc downstream‑regulated gene 2 suppresses the proliferation of T24 human bladder cancer cells via induction of oncosis

Jie Huang, Zhou Wu, Guangxiu Wang, Yingxian Cai, Minshan Cai, Yaozhang Li
Article Number: 67
Published online on: 15 December 2025

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Review Open Access

Deciphering epigenetic regulation in cardiac developmental toxicity: Mechanisms and implications (Review)

Ziling Qin, Ranran Chen, Dianrong Song
Article Number: 66
Published online on: 11 December 2025

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Review Open Access

Gut microbiota as a multifaceted modulator of prostate cancer: Mechanistic insights, therapeutic opportunities and clinical challenges (Review)

Zhenming Hao, Yongqiang Xie, Ru Zhang, Hui Sang, Luxi Li, Yulin Liu, Jinbo Hu, Jijun Wang, Keqiang Chai, Qiang Zhao
Article Number: 65
Published online on: 11 December 2025

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Expression of Concern Open Access

[Expression of Concern] lncRNA FLVCR1‑AS1 drives colorectal cancer progression via modulation of the miR‑381/RAP2A axis

Yi Han, Xiaoyan Wang, Enqiang Mao, Boyong Shen, Liang Huang
Article Number: 64
Published online on: 10 December 2025

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Review Open Access

Influence and treatment of insulin receptor substrate/PI3K/Akt‑mediated insulin resistance in diabetes mellitus (Review)

Weikang Tang, Huixia Liu, Xuan Li, Siyao Deng, Changyu Gao
Article Number: 63
Published online on: 09 December 2025

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Retraction Open Access

[Retracted] Long non‑coding RNA ANRIL knockdown suppresses apoptosis and pro‑inflammatory cytokines while enhancing neurite outgrowth via binding microRNA‑125a in a cellular model of Alzheimer’s disease

Bingling Zhou, Lijuan Li, Xin Qiu, Jiashun Wu, Lei Xu, Wei Shao
Article Number: 62
Published online on: 08 December 2025

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Review Open Access

Mitophagy and oxidative stress in chronic kidney disease (Review)

Quwu Mushuo, Yihuai Tian, Jianchun Li, Yanqin Qiu, Hui Fan, Qiongdan Hu, Qiong Zhang
Article Number: 61
Published online on: 04 December 2025

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ABCC9 knockdown attenuates isoproterenol‑induced myocardial hypertrophy by inhibiting the PI3K/AKT signaling pathway

Qian Peng, Rui Chang, Linlin Ma, Yanfei Li
Article Number: 60
Published online on: 04 December 2025

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Article

MeCP2 suppresses ferroptosis to drive EMT in retinal pigment epithelial cells: Implications for PVR pathogenesis

Sibei Guo, Yongya Zhang, Xue Li, Xueru Zhao, Yingjuan Liang, Xiaohua Li
Article Number: 59
Published online on: 04 December 2025

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Correction Open Access

[Corrigendum] Screening for implicated genes in colorectal cancer using whole‑genome gene expression profiling

Long-Ci Sun, Hai-Xin Qian
Article Number: 58
Published online on: 04 December 2025

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Article Open Access

Hyperoside prevents osteoporosis by activating the PI3K/AKT signaling pathway to inhibit oxidative stress and promote osteogenesis

Lirong Li, Huaidong Deng, Shabin Zhuan, Boyu Wu, Dawei Xiao
Article Number: 57
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] Interference with Tim‑3 protein expression attenuates the invasion of clear cell renal cell carcinoma and aggravates anoikis

Muming Yu, Bin Lu, Yancun Liu, Ying Me, Lijun Wang, Hui Li
Article Number: 56
Published online on: 01 December 2025

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Acetylshikonin induces ferroptosis via the lipid peroxidation pathway in osteosarcoma cells

Ji-Ying Chen, Guo-Shou Wang, Tsung-Ming Chang, Ju-Fang Liu
Article Number: 55
Published online on: 27 November 2025

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Review Open Access

Liver X receptor: A potential target for inflammatory bowel disease and colorectal cancer (Review)

Yingjie Li, Xiaoyan Fu, Meiwen Bai, Jiaqi Zhou, Jiatai Qiu, Hongxia Zhang, Shujuan Liang, Meifang Liu
Article Number: 54
Published online on: 27 November 2025

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Article Open Access

lncRNA NEAT1 promotes the proliferation of hemangioma cells by transcriptionally activating β‑catenin via enhancing H3K18 lactylation

Li Yu, Nian Zhou, Xiao-Liang Zhang, Xue-Jing Pang, Lu Xing, Yun-Jing Pu, Li Zhang, Jing-Nan Wu, Hong Shu
Article Number: 53
Published online on: 25 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑206 exerts anti‑oncogenic functions in esophageal squamous cell carcinoma by suppressing the c‑Met/AKT/mTOR pathway

Jin Zhang, Xianen Fa, Qingyong Zhang
Article Number: 52
Published online on: 25 November 2025

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Journal Cover
March-2026 Volume 33 Issue 3

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

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