|
1
|
Abdelaziz AI, Segaric J, Bartsch H, Petzhold D, Schlegel WP, Kott M, Seefeldt I, Klose J, Bader M, Haase H and Morano I: Functional characterization of the human atrial essential myosin light chain (hALC-1) in a transgenic rat model. J Mol Med (Berl). 82:265–274. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Gudbjartsson DF, Holm H, Sulem P, Masson G, Oddsson A, Magnusson OT, Saemundsdottir J, Helgadottir HT, Helgason H, Johannsdottir H, et al: A frameshift deletion in the sarcomere gene MYL4 causes early-onset familial atrial fibrillation. Eur Heart J. 38:27–34. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Petzhold D, Lossie J, Keller S, Werner S, Haase H and Morano I: Human essential myosin light chain isoforms revealed distinct myosin binding, sarcomeric sorting, and inotropic activity. Cardiovasc Res. 90:513–520. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Cadete VJJ, Arcand SA, Lin HB and Sawicki G: Synergistic protection of MLC 1 against cardiac ischemia/reperfusion- induced degradation: A novel therapeutic concept for the future. Future Med Chem. 5:389–398. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Zhang C, Wang G, Ji Z, Liu Z, Hou L, Liu G and Wang J: Molecular cloning, characterisation and mRNA expression analysis of the sheep myosin light chain 1 gene. Gene. 569:51–59. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Reiser PJ: Current understanding of conventional and novel co-expression patterns of mammalian sarcomeric myosin heavy chains and light chains. Arch Biochem Biophys. 662:129–133. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Kurabayashi M, Komuro I, Tsuchimochi H, Takaku F and Yazaki Y: Molecular cloning and characterization of human atrial and ventricular myosin alkali light chain cDNA clones. J Biol Chem. 263:13930–13936. 1988. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Morano M, Zacharzowski U, Maier M, Lange PE, Alexi-Meskishvili V, Haase H and Morano I: Regulation of human heart contractility by essential myosin light chain isoforms. J Clin Invest. 98:467–473. 1996. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Schaub MC, Hefti MA, Zuellig RA and Morano I: Modulation of contractility in human cardiac hypertrophy by myosin essential light chain isoforms. Cardiovasc Res. 37:381–404. 1998. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Szczesna D: Regulatory light chains of striated muscle myosin. Structure, function and malfunction. Curr Drug Targets Cardiovasc Haematol Disord. 3:187–197. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Markandran K, Poh JW, Ferenczi MA and Cheung C: Regulatory light chains in cardiac development and disease. Int J Mol Sci. 22:43512021. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Khalina YN, Bartsch H, Petzhold D, Haase H, Podlubnaya ZA, Shpagina MD and Morano I: Reconstitution of ventricular myosin with atrial light chains 1 improves its functional properties. Acta Biochim Pol. 52:443–448. 2005.PubMed/NCBI
|
|
13
|
Zhong U, Tang K, Li H, Zhao D, Kou W, Xu S, Zhang J, Yang H, Li S, Guo R, et al: Rs4968309 in myosin light chain 4 (MYL4) associated with atrial fibrillation onset and predicts clinical outcomes after catheter ablation in atrial fibrillation patients without structural heart disease. Circ J. 83:1994–2001. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Arrell KK, Neverova I, Fraser H, Marbán E and Van Eyk JE: Proteomic analysis of pharmacologically preconditioned cardiomyocytes reveals novel phosphorylation of myosin light chain 1. Circ Res. 89:480–487. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Zhang C, Wang J, Wang G, Ji Z, Hou L, Liu Z and Chao T: Molecular cloning and mRNA expression analysis of sheep MYL3 and MYL4 genes. Gene. 577:209–214. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Machackova J, Barta J and Dhalla NS: Myofibrillar remodelling in cardiac hypertrophy, heart failure and cardiomyopathies. Can J Cardiol. 22:953–968. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Petzhold D, Simsek B, Meißner R, Mahmoodzadeh S and Morano I: Distinct interactions between actin and essential myosin light chain isoforms. Biochem Biophys Res Commun. 449:284–288. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Ritter O, Luther HP, Haase H, Baltas LG, Baumann G, Schulte HD and Morano I: Expression of atrial myosin light chains but not α-myosin heavy chains is correlated in vivo with increased ventricular function in patients with hypertrophic obstructive cardiomyopathy. J Mol Med (Berl). 77:677–685. 1999. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Nakao K, Yasue H, Fujimoto K, Jougasaki M, Yamamoto H, Hitoshi Y, Takatsu K and Miyamoto E: Increased expression and regional differences of atrial myosin light chain 1 in human ventricles with old myocardial infarction: Analyses using two monoclonal antibodies. Circulation. 86:1727–1737. 1992. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Cummins P, Price KM and Littler WA: Foetal myosin light chain in human ventricle. J Muscle Res Cell Motil. 1:357–366. 1980. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Sitbon YH, Yadav S, Kazmierczak K and Szczesna-Cordary D: Insights into myosin regulatory and essential light chains: A focus on their roles in cardiac and skeletal muscle function, development and disease. J Muscle Res Cell Motil. 41:313–327. 2020. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Gregorich ZR, Cai W, Lin Z, Chen AJ, Peng Y, Kohmoto T and Ge Y: Distinct sequences and post-translational modifications in cardiac atrial and ventricular myosin light chains revealed by top-down mass spectrometry. J Mol Cell Cardiol. 107:13–21. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Bil-Lula I, Lin HB, Bialy D, Wawrzyńska M, Diebel L, Sawicka J, Woźniak M and Sawicki G: Subthreshold nitric oxide synthase inhibition improves synergistic effects of subthreshold MMP-2/MLCK-mediated cardiomyocyte protection from hypoxic injury. J Cell Mol Med. 20:1086–1094. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Morano I: Tuning the human heart molecular motors by myosin light chairs. J Mol Med. 77:544–555. 1999. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Sawicki G, Leon H, Sawicka J, Sariahmetoglu M, Schulze CJ, Scott PG, Szczesna-Cordary D and Schulz R: Degradation of myosin light chain in isolated rat hearts subjected to ischemia-reperfusion injury: A new intracellular target for matrix metalloproteinase-2. Circulation. 112:544–552. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Kwan JA, Schulze CJ, Wang W, Leon H, Sariahmetoglu M, Sung M, Sawicka J, Sims DE, Sawicki G and Schulz R: Matrix metalloproteinase-2 (MMP-2) is present in the nucleus of cardiac myocytes and is capable of cleaving poly (ADP-ribose) polymerase (PARP) in vitro. FASEB J. 18:690–692. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Sariahmetoglu M, Skrzypiec-Spring M, Youssef N, Jacob-Ferreira AL, Sawicka J, Holmes C, Sawicki G and Schulz R: Phosphorylation status of matrix metalloproteinase 2 in myocardial ischaemia-reperfusion injury. Heart. 98:656–662. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Wang W, Schulze CJ, Suarez-Pinzon WL, Dyck JR, Sawicki G and Schulz R: Intracellular action of matrix metalloproteinase-2 accounts for acute myocardial ischemia and reperfusion injury. Circulation. 106:1543–1549. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Li Y, Fang J, Hua Y, Wang C, Mu D and Zhou K: The study of fetal rat model of intra-amniotic isoproterenol injection induced heart dysfunction and phenotypic switch of contractile proteins. Biomed Res Int. 2014:3606872014. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Lin H Bin, Cadete VJJ, Sra B, Sawicka J, Chen Z, Bekar LK, Cayabyab F and Sawicki G: Inhibition of MMP-2 expression with siRNA increases baseline cardiomyocyte contractility and protects against simulated ischemic reperfusion injury. Biomed Res Int. 2014:8103712014. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Tsutsui H, Kinugawa S and Matsushima S: Oxidative stress and heart failure. Am J Physiol Hear Circ Physiol. 301:H2181–H2190. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Wang W, Sawicki G and Schulz R: Peroxynitrite-induced myocardial injury is mediated through matrix metalloproteinase-2. Cardiovasc Res. 53:165–174. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Krzywonos-Zawadzka A, Franczak A, Olejnik A, Radomski M, Gilmer JF, Sawicki G, Woźniak M and Bil-Lula I: Cardioprotective effect of MMP-2-inhibitor-NO-donor hybrid against ischaemia/reperfusion injury. J Cell Mol Med. 23:2836–2848. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Nattel S: Close connections between contraction and rhythm: A new genetic cause of atrial fibrillation/cardiomyopathy and what it can teach us. Eur Heart J. 38:35–37. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Hernandez OM, Jones M, Guzman G and Szczesna-Cordary D: Myosin essential light chain in health and disease. Am J Physiol Hear Circ Physiol. 292:H1643–H1654. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Kopylova G, Nabiev S, Nikitina L, Shchepkin D and Bershitsky S: The properties of the actin-myosin interaction in the heart muscle depend on the isoforms of myosin but not of α-actin. Biochem Biophys Res Commun. 476:648–653. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Sheehy SP, Pasqualini F, Grosberg A, Park SJ, Aratyn-Schaus Y and Parker KK: Quality metrics for stem cell-derived cardiac myocytes. Stem Cell Reports. 2:282–294. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Shchepkin DV, Nikitina LV, Bershitsky SY and Kopylova GV: The isoforms of α-actin and myosin affect the Ca2+ regulation of the actin-myosin interaction in the heart. Biochem Biophys Res Commun. 490:324–329. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Morano I and Haase H: Different actin affinities of human cardiac essential myosin light chain isoforms. FEBS Lett. 408:71–74. 1997. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Biały D, Wawrzyńska M, Bil-Lula I, Krzywonos-Zawadzka A, Sapa-Wojciechowska A, Arkowski J, Woźniak M and Sawicki G: Low frequency electromagnetic field decreases ischemia-reperfusion injury of human cardiomyocytes and supports their metabolic function. Exp Biol Med (Maywood). 243:809–816. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Heussen C and Dowdle EB: Electrophoretic analysis of plasminogen activators in polyacrylamide gels containing sodium dodecyl sulfate and copolymerized substrates. Anal Biochem. 102:196–202. 1980. View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Barton PJ and Buckingham ME: The myosin alkali light chain proteins and their genes. Biochem J. 231:249–261. 1985. View Article : Google Scholar : PubMed/NCBI
|
|
43
|
Logvinova DS, Matyushenko AM, Nikolaeva OP, Nikolaeva OP and Levitsky DI: Transient interaction between the N-terminal extension of the essential light chain-1 and motor domain of the myosin head during the ATPase cycle. Biochem Biophys Res Commun. 495:163–167. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
44
|
Haase H, Dobbernack G, Tünnemann G, Karczewski P, Cardoso C, Petzhold D, Schlegel WP, Lutter S, Pierschalek P, Behlke J and Morano I: Minigenes encoding N-terminal domains of human cardiac myosin light chain-1 improve heart function of transgenic rats. FASEB J. 20:865–873. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
45
|
Sutsch G, Brunner UT, Von Schulthess C, Hirzel HO, Hess OM, Turina M, Krayenbuehl HP and Schaub MC: Hemodynamic performance and myosin light chain-1 expression of the hypertrophied left ventricle in aortic valve disease before and after valve replacement. Circ Res. 70:1035–1043. 1992. View Article : Google Scholar : PubMed/NCBI
|
|
46
|
Cummins P: Transitions in human atrial and ventricular myosin light-chain isoenzymes in response to cardiac-pressure-overload-induced hypertrophy. Biochem J. 205:195–204. 1982. View Article : Google Scholar : PubMed/NCBI
|
|
47
|
Diffee GM, Seversen EA, Stein TD and Johnson JA: Microarray expression analysis of effects of exercise training: Increase in atrial MLC-1 in rat ventricles. Am J Physiol Hear Circ Physiol. 284:H830–H837. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
48
|
Fujimoto K, Yasue H, Nakao K, Yamamoto H, Hitoshi Y, Jougasaki M, Okumura K, Ogawa H, Takatsu K and Miyamoto E: Novel monoclonal antibodies specific for human cardiac myosin light-chain 1: Useful tools for analysis of normal and pathological hearts. J Histochem Cytochem. 41:35–42. 1993. View Article : Google Scholar : PubMed/NCBI
|
|
49
|
Schaub MC, Tuchschmid CR, Srihari T and Hirzel HO: Myosin isoenzymes in human hypertrophic hearts. Shift in atrial myosin heavy chains and in ventricular myosin light chains. Eur Heart J. 5 (Suppl F):S85–S93. 1984. View Article : Google Scholar : PubMed/NCBI
|
|
50
|
Olejnik A, Krzywonos-Zawadzka A, Banaszkiewicz M and Bil-Lula I: Ameliorating effect of Klotho protein on rat heart during I/R injury. Oxid Med Cell Longev. 2020:64272842020. View Article : Google Scholar : PubMed/NCBI
|
|
51
|
Cadete VJJ, Sawicka J, Jaswal JS, Lopaschuk GD, Schulz R, Szczesna-Cordary D and Sawicki G: Ischemia/reperfusion-induced myosin light chain 1 phosphorylation increases its degradation by matrix metalloproteinase 2. FEBS J. 279:2444–2454. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
52
|
Turer AT and Hill JA: Pathogenesis of myocardial ischemia-reperfusion injury and rationale for therapy. Am J Cardiol. 106:360–368. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
53
|
Bil-Lula I, Krzywonos-Zawadzka A, Sawicka J, Bialy D, Wawrzynska M, Wozniak M and Sawicki G: L-NAME improves doxycycline and ML-7 cardioprotection from oxidative stress. Front Biosci (Landmark Ed). 23:298–309. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
54
|
Banaszkiewicz M, Krzywonos-Zawadzka A, Olejnik A and Bil-Lula I: Tissue expression of atrial and ventricular myosin light chains in the mechanism of adaptation to oxidative stress. Int J Mol Sci. 21:83842020. View Article : Google Scholar : PubMed/NCBI
|
|
55
|
Cheung PY, Sawicki G, Wozniak M, Wang W, Radomski MW and Schulz R: Matrix metalloproteinase-2 contributes to ischemia-reperfusion injury in the heart. Circulation. 101:1833–1839. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
56
|
Ben-Yosef Y, Lahat N, Shapiro S, Bitterman H and Miller A: Regulation of endothelial matrix metalloproteinase-2 by hypoxia/reoxygenation. Circ Res. 90:784–791. 2002. View Article : Google Scholar : PubMed/NCBI
|
