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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
November-2021 Volume 24 Issue 5

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

PPM1A as a key target of the application of Jiawei‑Maxing‑Shigan decoction for the attenuation of radiation‑induced epithelial‑mesenchymal transition in type II alveolar epithelial cells

Jinhua Lu, Shengyou Lin, Zechen Lin, Xianlei Lin, Yuezhong Shen, Jingyang Su
Article Number: 825
Published online on: 24 September 2021

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Article Open Access

Intermittent hypoxia mimicking obstructive sleep apnea aggravates early brain injury following ICH via neuroinflammation and apoptosis

Wenjing Fei, Wei Jiao, Xiaoyan Feng, Xufeng Chen, Yuhai Wang
Article Number: 824
Published online on: 24 September 2021

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Article Open Access

PPARγ attenuates hepatic inflammation and oxidative stress of non‑alcoholic steatohepatitis via modulating the miR‑21‑5p/SFRP5 pathway

Xiying Zhang, Fang Deng, Yuping Zhang, Xiaohong Zhang, Jianfei Chen, Youzhao Jiang
Article Number: 823
Published online on: 24 September 2021

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Article Open Access

Role of salt‑inducible kinase 2 in the malignant behavior and glycolysis of colorectal cancer cells

Xiaohong Ni, Yongjiang Feng, Xiangwei Fu
Article Number: 822
Published online on: 24 September 2021

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Article Open Access

Ginsenoside Rk1 protects human melanocytes from H2O2‑induced oxidative injury via regulation of the PI3K/AKT/Nrf2/HO‑1 pathway

Jian Xiong, Jianing Yang, Kai Yan, Jing Guo
Article Number: 821
Published online on: 24 September 2021

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Article Open Access

Let‑7b‑5p promotes cell apoptosis in Parkinson's disease by targeting HMGA2

Yujing Huang, Ying Liu, Jing Huang, Lu Gao, Zhenggang Wu, Lu Wang, Lin Fan
Article Number: 820
Published online on: 24 September 2021

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Article Open Access

HOXD9‑induced SCNN1A upregulation promotes pancreatic cancer cell proliferation, migration and predicts prognosis by regulating epithelial‑mesenchymal transformation

Jinhai Chang, Xuguang Hu, Jinniang Nan, Xianghua Zhang, Xintian Jin
Article Number: 819
Published online on: 22 September 2021

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Article Open Access

Knockdown of miR‑205‑5p alleviates the inflammatory response in allergic rhinitis by targeting B‑cell lymphoma 6

Shuang Zhang, Sihan Lin, Qiaofei Tang, Zhiyong Yan
Article Number: 818
Published online on: 22 September 2021

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Article Open Access

NUAK2 silencing inhibits the proliferation, migration and epithelial‑to‑mesenchymal transition of cervical cancer cells via upregulating CYFIP2

Yuxia Li, Xiaohui Song, Liping Liu, Lei Yue
Article Number: 817
Published online on: 22 September 2021

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Retraction Open Access

[Retracted] Downregulation of caspase‑3 alleviates Mycoplasma pneumoniae‑induced apoptosis in alveolar epithelial cells

Shan Shi, Xiaolei Liu, Haibo Li
Article Number: 816
Published online on: 22 September 2021

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Article Open Access

Exosomes in serum‑free cultures of THP‑1 macrophages infected with Mycobacterium tuberculosis

Fantahun Biadglegne, Phil Rademacher, Yarúa Gabriela Jaimes De Sulbaran, Brigitte König, Arne C. Rodloff, Ulrike Zedler, Anca Dorhoi, Ulrich Sack
Article Number: 815
Published online on: 22 September 2021

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Article Open Access

NF‑κB/IκBα signaling pathways are essential for resistance to heat stress‑induced ROS production in pulmonary microvascular endothelial cells

Weidang Xie, Wei Huang, Shumin Cai, Hui Chen, Weijun Fu, Zhongqing Chen, Yanan Liu
Article Number: 814
Published online on: 22 September 2021

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Article Open Access

Interleukin‑Iβ promotes cartilage degeneration by regulating forkhead box protein O4 and type Ⅱ collagen

Jianxiong Wu, Hongjun Zhang, Rulin Deng, Lifeng Xing, Mingwu Hu, Xiaoling Fu
Article Number: 813
Published online on: 20 September 2021

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Article Open Access

miR‑125a‑5p reverses epithelial‑mesenchymal transition and restores drug sensitivity by negatively regulating TAFAZZIN signaling in breast cancer

Dongmei Li, Limei Chen, Xiaofang Zhang, Yanhua Wang, Chuansheng Huang, Jianglong Li, Feilong He, Wenxing He
Article Number: 812
Published online on: 20 September 2021

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Article Open Access

Silencing circ‑BIRC6 inhibits the proliferation, invasion, migration and epithelial‑mesenchymal transition of bladder cancer cells by targeting the miR‑495‑3p/XBP1 signaling axis

Lei Zhou, Bingzhi Wang, Yichuan Zhang, Kun Yao, Bin Liu
Article Number: 811
Published online on: 20 September 2021

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Retraction Open Access

[Retracted] MicroRNA‑338‑3p suppresses tumor growth of esophageal squamous cell carcinoma in vitro and in vivo

Xinyu Li, Zhihong Li, Guiyun Yang, Zhenxiang Pan
Article Number: 810
Published online on: 20 September 2021

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Correction Open Access

[Corrigendum] FOXO3a‑mediated suppression of the self‑renewal capacity of sphere‑forming cells derived from the ovarian cancer SKOV3 cell line by 7‑difluoromethoxyl‑5,4’‑di‑n‑octyl genistein

Yingxia Ning, Chaoyuan Luo, Kaiqun Ren, Meifang Quan, Jianguo Cao
Article Number: 809
Published online on: 17 September 2021

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Correction Open Access

[Corrigendum] Effect of Yi Guan Jian decoction on differentiation of bone marrow mesenchymal stem cells into hepatocyte‑like cells in dimethylnitrosamine‑induced liver cirrhosis in mice

Yan Xiang, Bing-Yao Pang, Yuan Zhang, Qiao-Ling Xie, Ying Zhu, Ai-Jing Leng, Long-Qing Lu, Hai-Long Chen
Article Number: 808
Published online on: 17 September 2021

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Article

JMJD3 deficiency alleviates lipopolysaccharide‑induced acute lung injury by inhibiting alveolar epithelial ferroptosis in a Nrf2‑dependent manner

Junwei Peng, Bin Fan, Chuanming Bao, Chen Jing
Article Number: 807
Published online on: 17 September 2021

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Article Open Access

Upregulation of miR‑335 exerts protective effects against sepsis‑induced myocardial injury

Xian Long, Yongpan Huang, Jianbin He, Xiang Zhang, Yan Zhou, Yingmin Wei, Ying Tang, Lijing Liu
Article Number: 806
Published online on: 17 September 2021

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Article Open Access

Cycloastragenol alleviates airway inflammation in asthmatic mice by inhibiting autophagy

Xueyi Zhu, Yuxue Cao, Mingyue Su, Mengmeng Chen, Congcong Li, La Yi, Jingjing Qin, Wuniqiemu Tulake, Fangzhou Teng, Yuanyuan Zhong, Weifeng Tang, Shiyuan Wang, Jingcheng Dong
Article Number: 805
Published online on: 17 September 2021

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Correction Open Access

[Corrigendum] Murine and Chinese cobra venom‑derived nerve growth factor stimulate chondrogenic differentiation of BMSCs in vitro: A comparative study

Zhikang Miao, Zhenhui Lu, Shixing Luo, Danqing Lei, Yi He, Huayu Wu, Jinmin Zhao, Li Zheng
Article Number: 804
Published online on: 16 September 2021

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Article

Novel compound heterozygous mutations in CYP1B1 identified in a Chinese family with developmental glaucoma

Suping Cai, Daren Zhang, Xiaodong Jiao, Tingting Wang, Mengjie Fan, Yun Wang, James Fielding Hejtmancik, Xuyang Liu
Article Number: 803
Published online on: 15 September 2021

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Article Open Access

Triamcinolone acetonide modulates TGF‑β2‑induced angiogenic and tissue‑remodeling effects in cultured human retinal pigment epithelial cells

Chih-Cheng Hsiao, Yo-Chen Chang, Yu-Ting Hsiao, Po-Han Chen, Ming-Chu Hsieh, Wen-Chuan Wu, Ying-Hsien Kao
Article Number: 802
Published online on: 14 September 2021

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Article Open Access

Ginsenoside Rg1 ameliorates aging‑induced liver fibrosis by inhibiting the NOX4/NLRP3 inflammasome in SAMP8 mice

Yan Li, Duoduo Zhang, Lan Li, Yuli Han, Xianan Dong, Liu Yang, Xuewang Li, Weizu Li, Weiping Li
Article Number: 801
Published online on: 14 September 2021

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Article Open Access

PLAC1 is an independent predictor of poor survival, and promotes cell proliferation and invasion in cervical cancer

Rujun Chen, Chan Sheng, Ruyue Ma, Liwen Zhang, Lina Yang, Yaping Chen
Article Number: 800
Published online on: 14 September 2021

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Article Open Access

α‑rhamnrtin‑3‑α‑rhamnoside exerts anti‑inflammatory effects on lipopolysaccharide‑stimulated RAW264.7 cells by abrogating NF‑κB and activating the Nrf2 signaling pathway

Jiang Tao Zhou, Kai Da Ren, Jing Hou, Jie Chen, Guan'e Yang
Article Number: 799
Published online on: 14 September 2021

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Article Open Access

Circular RNA hsa_circ_0026552 inhibits the proliferation, migration and invasion of trophoblast cells via the miR‑331‑3p/TGF‑βR1 axis in pre‑eclampsia

Li Shan, Xiaofei Hou
Article Number: 798
Published online on: 14 September 2021

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Article Open Access

Transcription factor HOXC10 activates the expression of MTFR2 to regulate the proliferation, invasion and migration of colorectal cancer cells

Ying Xie, Ran Chen, Liujia Yan, Zhangjun Jia, Guangshu Liang, Qin Wang
Article Number: 797
Published online on: 14 September 2021

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Article Open Access

FOXO3a inhibits nephroblastoma cell proliferation, migration and invasion, and induces apoptosis through downregulating the Wnt/β‑catenin signaling pathway

Cheng Qian, Qiang Liu
Article Number: 796
Published online on: 13 September 2021

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Article Open Access

Exosomal‑miR‑1184 derived from mesenchymal stem cells alleviates cisplatin‑associated acute kidney injury Corrigendum in /10.3892/mmr.2022.12757

Jinshi Zhang, Wenfang He, Danna Zheng, Qiang He, Mingming Tan, Juan Jin
Article Number: 795
Published online on: 13 September 2021

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Article

Knockdown of lncRNA PVT1 inhibits the proliferation and accelerates the apoptosis of colorectal cancer cells via the miR‑761/MAPK1 axis

Yujing Liu, Yongyou Wu, Zhu Zhu, Jiangbo Gong, Wenhuan Dou
Article Number: 794
Published online on: 13 September 2021

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Article Open Access

MicroRNA‑532‑5p regulates oxidative stress and insulin secretion damage in high glucose‑induced pancreatic β cells by downregulating the expression levels of CCND1

Zhibiao Zhong, Weilan Su, Hongmei Chen
Article Number: 793
Published online on: 10 September 2021

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Article

Rab6c is a new target of miR‑218 that can promote the progression of bladder cancer

Long He, Xiang Pan, Xialu Wang, Yuhua Cao, Peng Chen, Cheng Du, Daifa Huang
Article Number: 792
Published online on: 10 September 2021

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Article Open Access

Buyang Huanwu Decoction promotes neurogenesis via sirtuin 1/autophagy pathway in a cerebral ischemia model

Han Li, Dong Peng, Shi-Jie Zhang, Yang Zhang, Qi Wang, Li Guan
Article Number: 791
Published online on: 10 September 2021

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Article Open Access

Amelioration of alcohol‑induced gastric mucosa damage by oral administration of food‑polydeoxyribonucleotides

Jonghwan Kim, Soyoung Chun, Seul-Ong Ohk, Sanghoon Kim, Juwan Kim, Sungoh Lee, Hangyu Kim, Sujong Kim
Article Number: 790
Published online on: 09 September 2021

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Article Open Access

Inhibin βA is an independent prognostic factor that promotes invasion via Hippo signaling in non‑small cell lung cancer

Yijun Zhang, Shumei Yan, Yan Li, Jiangbo Zhang, Yuan Luo, Pengcheng Li, Yuanzhong Yang, Yong Li, Yuhua Huang, Enhua Wang
Article Number: 789
Published online on: 09 September 2021

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Review Open Access

Effects of miRNAs, lncRNAs and circRNAs on osteoporosis as regulatory factors of bone homeostasis (Review)

Zhichao Li, Haipeng Xue, Guoqing Tan, Zhanwang Xu
Article Number: 788
Published online on: 09 September 2021

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Article Open Access

Schizandrin A induces the apoptosis and suppresses the proliferation, invasion and migration of gastric cancer cells by activating endoplasmic reticulum stress

Huachao Pu, Qian Qian, Fuli Wang, Minjie Gong, Xinguo Ge
Article Number: 787
Published online on: 09 September 2021

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Article Open Access

circFLNA promotes glioblastoma proliferation and invasion by negatively regulating miR‑199‑3p expression

Yu Sun, Guangtao Ma, Hongtao Xiang, Xiaomin Wang, Hanmei Wang, Yan Zhang, Fuzhong Qie, Chenlong Li
Article Number: 786
Published online on: 08 September 2021

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Article Open Access

Emodin inhibits the progression of acute pancreatitis via regulation of lncRNA TUG1 and exosomal lncRNA TUG1

Xiumei Wen, Beihui He, Xing Tang, Bin Wang, Zhiyun Chen
Article Number: 785
Published online on: 08 September 2021

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Article

Long non‑coding RNA FGD5‑AS1/microRNA‑133a‑3p upregulates aquaporin 1 to decrease the inflammatory response in LPS‑induced sepsis

Yuru Chu, Xu Wang, Naihao Yu, Yali Li, Jianying Kan
Article Number: 784
Published online on: 07 September 2021

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Article Open Access

Upregulation of RIP3 promotes necroptosis via a ROS‑dependent NF‑κB pathway to induce chronic inflammation in HK‑2 cells

Junjun Wei, Liangliang Chen, Duidui Wang, Li Tang, Zhenhua Xie, Weifeng Chen, Shuwei Zhang, Guobin Weng
Article Number: 783
Published online on: 07 September 2021

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Article Open Access

lncRNA TPT1‑AS1 knockdown inhibits liver cancer cell proliferation, migration and invasion

Hao Li, Jing Jin, Jianchun Xian, Wei Wang
Article Number: 782
Published online on: 07 September 2021

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Article Open Access

LncRNA LINC00963 promotes colorectal cancer cell proliferation and metastasis by regulating miR‑1281 and TRIM65

Haidong Lv, Dixia Zhou, Guoqing Liu
Article Number: 781
Published online on: 07 September 2021

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Article Open Access

Long non‑coding RNA ZSCAN16‑AS1 promotes the malignant properties of hepatocellular carcinoma by decoying microRNA‑451a and consequently increasing ATF2 expression

Chaohua Lv, Qingsong Wan, Chengxiang Shen, Hongsheng Wu, Bin Zhou, Weiwei Wang
Article Number: 780
Published online on: 07 September 2021

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Article Open Access

Paeonol alleviates lipopolysaccharide‑induced hepatocytes injury through alteration of mitochondrial function and NF‑κB translocation

Shouzhu Xu, Jie Xu, Ting Hao, Yu Yan, Shihao Zhang, Aihong Li, Chuandao Shi, Qiling Liu, Jing Zhao
Article Number: 779
Published online on: 07 September 2021

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Article Open Access

Lycium barbarum polysaccharide protects rats and cardiomyocytes against ischemia/reperfusion injury via Nrf2 activation through autophagy inhibition

Hao Pan, Lin Niu, Yihao Wu, Liuying Chen, Xiaowei Zhou, Yan Zhao
Article Number: 778
Published online on: 07 September 2021

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Article Open Access

miR221 regulates TGF-β1-induced HSC activation through inhibiting autophagy by directly targeting LAMP2

Ran Cheng, Hao Xu, Yang Hong
Article Number: 777
Published online on: 07 September 2021

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Article Open Access

Protective effect of parecoxib sodium against ischemia reperfusion‑induced intestinal injury

Mei Li, Zhi Zheng
Article Number: 776
Published online on: 07 September 2021

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Article Open Access

Phillygenin inhibits the inflammation and apoptosis of pulmonary epithelial cells by activating PPARγ signaling via downregulation of MMP8

Yufeng Lin, Peng Yang
Article Number: 775
Published online on: 06 September 2021

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Article Open Access

ADAM10 attenuates the development of abdominal aortic aneurysms in a mouse model

Renfeng Qiu, Shuxiao Chen, Peixian Gao, Kun Luo, Xuedong Feng, Hai Yuan, Xuejun Wu, Gang Li
Article Number: 774
Published online on: 06 September 2021

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Article Open Access

Remote ischemic post‑conditioning alleviates ischemia/reperfusion‑induced intestinal injury via the ERK signaling pathway‑mediated RAGE/HMGB axis

Lei Mi, Nan Zhang, Jiyun Wan, Ming Cheng, Jianping Liao, Xiao Zheng
Article Number: 773
Published online on: 06 September 2021

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Article Open Access

Naringin induces apoptosis of gastric carcinoma cells via blocking the PI3K/AKT pathway and activating pro‑death autophagy

Cuixiang Xu, Xiaoyan Huang, Yubin Huang, Xiao Liu, Min Wu, Jianhua Wang, Xianglong Duan
Article Number: 772
Published online on: 06 September 2021

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Article Open Access

miR‑486‑5p suppresses gastric cancer cell growth and migration through downregulation of fibroblast growth factor 9

Weiwei Wei, Chunyu Liu, Rongrong Yao, Qingyun Tan, Qingdong Wang, Hao Tian
Article Number: 771
Published online on: 03 September 2021

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Article Open Access

Expression of atrial‑fetal light chains in cultured human cardiomyocytes after chemical ischemia‑reperfusion injury

Marta Banaszkiewicz, Agnieszka Olejnik, Anna Krzywonos‑Zawadzka, Kornela Hałucha, Iwona Bil‑Lula
Article Number: 770
Published online on: 03 September 2021

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Article Open Access

Lycium barbarum polysaccharide protects ARPE‑19 cells against H2O2‑induced oxidative stress via the Nrf2/HO‑1 pathway

Ran Liang, Qi Zhao, Qing Zhu, Xin He, Mingjun Gao, Yiru Wang
Article Number: 769
Published online on: 03 September 2021

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Review Open Access

Overview of the molecular mechanisms contributing to the formation of cancer‑associated adipocytes (Review)

Yunpeng Tang, Wenkai Zhang, Tianqiang Sheng, Xi He, Xiangyang Xiong
Article Number: 768
Published online on: 03 September 2021

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Article Open Access

Parallel evaluation of cell‑based phage display panning strategies: Optimized selection and depletion steps result in AML blast‑binding consensus antibodies

Theresa Weber, Sibylle Pscherer, Ulrike Gamerdinger, Andrea Teigler‑Schlegel, Natalja Rutz, Wolfgang Blau, Mathias Rummel, Stefan Gattenlöhner, Mehmet Kemal Tur
Article Number: 767
Published online on: 03 September 2021

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Article Open Access

Regulation of the PTEN/PI3K/AKT pathway in RCC using the active compounds of natural products in vitro

Xue Wang, Zhenhua Xie, Zhongguan Lou, Yulu Chen, Shuaishuai Huang, Yu Ren, Guobin Weng, Shuwei Zhang
Article Number: 766
Published online on: 03 September 2021

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Article Open Access

Silencing of PFKFB3 protects podocytes against high glucose‑induced injury by inducing autophagy

Zhengming Zhu, Qingsheng Liu, Jianshi Sun, Ziyang Bao, Weiwei Wang
Article Number: 765
Published online on: 03 September 2021

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Article Open Access

High glucose‑induced upregulation of CD36 promotes inflammation stress via NF‑κB in H9c2 cells

Baosheng Han, Jianzhong Wang, Jiawei Wu, Fang Yan, Yaru Wang, Jun Li
Article Number: 764
Published online on: 03 September 2021

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Article Open Access

Salvianolic acid B improves autophagic dysfunction and decreases the apoptosis of cholesterol crystal‑induced macrophages via inhibiting the Akt/mTOR signaling pathway

Mengqi Sun, Yun Ye, Yilan Huang, Wenxian Yin, Zhaolan Yu, Shurong Wang
Article Number: 763
Published online on: 03 September 2021

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Long non‑coding RNA HAND2‑AS1/miR‑106a/PTEN axis re‑sensitizes cisplatin‑resistant ovarian cells to cisplatin treatment

Lijun Li, Li Li, Lian Hu, Ting Li, Dan Xie, Xiaoliu Liu
Article Number: 762
Published online on: 02 September 2021

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Ribosomal RNA‑depleted RNA sequencing reveals the pathogenesis of refractory Mycoplasma pneumoniae pneumonia in children

Feng Huang, Huifeng Fan, Diyuan Yang, Junsong Zhang, Tingting Shi, Dongwei Zhang, Gen Lu
Article Number: 761
Published online on: 02 September 2021

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Sirtuin 2 knockdown inhibits cell proliferation and RAS/ERK signaling, and promotes cell apoptosis and cell cycle arrest in multiple myeloma

Tianling Ding, Jie Hao
Article Number: 760
Published online on: 02 September 2021

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Effect of N‑terminal region of human parvovirus B19‑VP1 unique region on cardiac injury in naïve mice

Kuo-Chuan Hung, Zi-Yun Huang, Jia Le Yow, Tsai-Ching Hsu, Bor-Show Tzang
Article Number: 759
Published online on: 02 September 2021

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Article Open Access

Exosomes from miR-29a-modified adipose-derived mesenchymal stem cells reduce excessive scar formation by inhibiting TGF-β2/Smad3 signaling

Ruihong Yuan, Xiaoming Dai, Yisong Li, Chunshan Li, Liu Liu
Article Number: 758
Published online on: 02 September 2021

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Article Open Access

LINC00238 inhibits hepatic carcinoma progression by activating TMEM106C‑mediated apoptosis pathway

Caihua Jiang, Feng Li, Meng Yang, Jianping Duan, Jianming Lai, Shulun Sun, Shaohua Fan
Article Number: 757
Published online on: 02 September 2021

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Overexpression of EphB4 promotes neurogenesis, but inhibits neuroinflammation in mice with acute ischemic stroke

Jin Wang, Zun Zhang, Shaojing Fu, Xiaojie Li, Xinhui Li, Shaobin Wang, Lihe Yuan
Article Number: 756
Published online on: 02 September 2021

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Gycyrrhizic acid alleviates atherosclerotic lesions in rats with diabetes mellitus

Yaodong Zhao, Wei Li, Daimin Zhang
Article Number: 755
Published online on: 02 September 2021

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Article Open Access

Atrial natriuretic peptide protects vertebral endplate chondrocytes against H2O2‑induced apoptosis and oxidative stress through activation of the Nrf2/HO‑1 signaling pathway

Feiping He, Jingying Gai, Jun Wang, Lei Tang, Yifeng Liu, Qingchun Feng
Article Number: 754
Published online on: 01 September 2021

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MicroRNA‑502‑3p promotes Mycobacterium tuberculosis survival in macrophages by modulating the inflammatory response by targeting ROCK1

Fang Liu, Zhen Dong, Yuefu Lin, Haibo Yang, Pingping Wang, Yongxia Zhang
Article Number: 753
Published online on: 01 September 2021

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Article Open Access

miR‑32‑5p suppresses the proliferation and migration of pancreatic adenocarcinoma cells by targeting TLDC1

Peng Yuan, Chaofeng Tang, Bendong Chen, Peng Lei, Jianjun Song, Guojun Xin, Zuozheng Wang, Yongfeng Hui, Weijie Yao, Genwang Wang, Guozhong Zhao
Article Number: 752
Published online on: 31 August 2021

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Retraction Open Access

[Retracted] Downregulation of matrix metalloproteinase 9 by small interfering RNA inhibits the tumor growth of ovarian epithelial carcinoma in vitro and in vivo

Fengjun Guo, Jingyan Tian, Manhua Cui, Meiru Fang, Lin Yang
Article Number: 751
Published online on: 31 August 2021

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Article

Tumor necrosis factor α‑induced protein 8‑like 2 contributes to penehyclidine hydrochloride pretreatment against lipopolysaccharide‑induced acute lung injury in a mouse model

Min Yuan, Guoqing Jing, Qian Kong, Tingqian Ming, Xuemin Song, Xiaojing Wu
Article Number: 750
Published online on: 31 August 2021

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Article

NEAT1 silencing alleviates pulmonary arterial smooth muscle cell migration and proliferation under hypoxia through regulation of miR‑34a‑5p/KLF4 in vitro

Xiuli Dou, Yuxiao Ma, Yijie Qin, Qinglin Dong, Shouwei Zhang, Rui Tian, Mingyu Pan
Article Number: 749
Published online on: 31 August 2021

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Article Open Access

Knockdown of MIR9‑3HG inhibits proliferation and promotes apoptosis of cervical cancer cells by miR‑498 via EP300

Fang Li, Ying Liang, Pian Ying
Article Number: 748
Published online on: 31 August 2021

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Serum‑derived exosomes from house dust mite‑sensitized guinea pigs contribute to inflammation in BEAS‑2B cells via the TLR4‑NF‑κB pathway

Chao Liu, Xiao-Lin Huang, Jian-Ping Liang, Xu Zhong, Zi-Feng Wei, Li-Xue Dai, Jun Wang
Article Number: 747
Published online on: 27 August 2021

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Involvement of autophagy in diosgenin‑induced megakaryocyte differentiation in human erythroleukemia cells

Dima Diab, Aline Pinon, Catherine Ouk, Rouba Hage‑Sleiman, Mona Diab‑Assaf, Bertrand Liagre, David Yannick Leger
Article Number: 746
Published online on: 27 August 2021

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Review

SLC26A6 and NADC‑1: Future direction of nephrolithiasis and calculus‑related hypertension research (Review)

Xingyue Yang, Shun Yao, Jiaxing An, Hai Jin, Hui Wang, Biguang Tuo
Article Number: 745
Published online on: 26 August 2021

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O‑GlcNAcylation contributes to intermittent hypoxia‑associated vascular dysfunction via modulation of MAPKs but not CaMKII pathways

Xueling Guo, Yan Deng, Linghui Zhan, Jin Shang, Huiguo Liu
Article Number: 744
Published online on: 25 August 2021

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Silencing the lncRNA NORAD inhibits EMT of head and neck squamous cell carcinoma stem cells via miR‑26a‑5p

Weiming Hu, Yong Zhao, Lizhong Su, Zuliang Wu, Wenjing Jiang, Xiaoze Jiang, Ming Liu
Article Number: 743
Published online on: 25 August 2021

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Article Open Access

Alteration of immune profiles is associated with pulmonary function and symptoms in patients with chronic obstructive pulmonary disease

Sixiang Li, Shuang Zhao, Zhenru Wu, Fangfang Wang, Weimin Li
Article Number: 742
Published online on: 24 August 2021

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Article Open Access

Protective effect of carvacrol on liver injury in type 2 diabetic db/db mice

Wei Zhao, Li Chen, Heng Zhou, Chunyan Deng, Qizhen Han, Yonghua Chen, Qing Wu, Shanshan Li
Article Number: 741
Published online on: 24 August 2021

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Journal Cover
June-2026 Volume 33 Issue 6

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

Mechanotransducer Piezo1 drives ventilator‑induced lung injury in lung epithelial cells via the calcineurin/NFATc3 pathway

Min Li, Shu-Li Zhang, Feng Yuan, Dan Feng
Article Number: 183
Published online on: 28 April 2026

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Review Open Access

Oncogene c‑Myc: From molecular mechanism to targeted therapy (Review)

Jianjun Lu, Jing Zhu, Liqiong Zhang, Xiang Zheng, Shan Yang, Yatong Sang, Mingli Yang, Yu Tang
Article Number: 182
Published online on: 28 April 2026

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Indium (III) chloride inhibits testicular Leydig cell proliferation by disrupting centrosome copy numbers

Chia-Yih Wang, Ping-Jui Su, Kuan-Chih Wang, Ruei-Ci Lin, Min-Yun Ke, Yen-Ni Teng
Article Number: 181
Published online on: 28 April 2026

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Correction Open Access

[Corrigendum] Inhibition of DNA‑PK activity sensitizes A549 cells to X‑ray irradiation by inducing the ATM‑dependent DNA damage response

Lina Yang, Xinrui Yang, Yiwei Tang, Defu Zhang, Lijie Zhu, Shengnan Wang, Bo Wang, Tao Ma
Article Number: 180
Published online on: 27 April 2026

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Review Open Access

Natural products and neurocognitive disorders: Mechanistic insights and research advances (Review)

Weiqing Li, Wei Wu, Xiaoqing Huang, Yinghai Liu, Gu Gong, Qingqing Huang
Article Number: 179
Published online on: 27 April 2026

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Review Open Access

Research progress and future directions in circadian rhythms for uterine‑related diseases (Review)

Tiantian Ma, Junwei Li, Yi Fang, Tiancheng Xu, Qian Li, Liangjun Xia, Youbing Xia
Article Number: 178
Published online on: 27 April 2026

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Therapeutic potential of tertiary lymphoid structures in breast cancer (Review)

Liangxiao Zhu, Meigui Li, Feng Liu, Fenghou Gao
Article Number: 177
Published online on: 24 April 2026

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Retraction Open Access

[Retracted] Prognostic and predictive roles of microRNA‑411 and its target STK17A in evaluating radiotherapy efficacy and their effects on cell migration and invasion via the p53 signaling pathway in cervical cancer

Wei Wei, Cun Liu
Article Number: 176
Published online on: 22 April 2026

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Review Open Access

Insights into nuciferine: A natural multifunctional bioactive alkaloid (Review)

Yulin Liu, Xinye Li, Bo Huang, Xudong Lai, Baoqing Ye, Haixiong Miao, Lixian Zhang, Xifeng Xiong
Article Number: 175
Published online on: 22 April 2026

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Article

Urinary 8‑OHdG and MDA as rapid biodosimetry markers in the lethal/sublethal dose range

Satoru Monzen, Kenji Terada, Yusuke Tawata, Takanori Sato, Nozomi Kousaka, Yasushi Mariya
Article Number: 174
Published online on: 22 April 2026

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Retraction Open Access

[Retracted] Treatment with harmine ameliorates functional impairment and neuronal death following traumatic brain injury  

Zeqi Zhong, Yuan Tao, Hui Yang
Article Number: 173
Published online on: 20 April 2026

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Article Open Access

SRSF1 as a promising biomarker and key player in the pathogenesis of Alzheimer's disease

Yanchen Liu, Yi Zhao, Yanting Yao, Dan Liu, Yilei Sun, Weishi Xu, Hongli Yu, Lijun Chi
Article Number: 172
Published online on: 17 April 2026

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Article Open Access

RUVBL1 and CRAF promote periodontal ligament stem cell osteogenic differentiation via the MEK/ERK signaling cascade

Xin-Yu Zhang, Peiqi Hao, Ming-Yue Qi, Hui Guo
Article Number: 171
Published online on: 16 April 2026

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Porphyromonas gingivalis triggers lipid metabolism disorders in atherosclerosis through the PPARγ-LXRα‑ABCA1/ABCG1 signaling pathway

Xue-Jing Lin, Min Yao, Wan-Yun Lin, Qin Yuan, Jie Zhou, Wen-Xuan Xia, Yu-Lei Dong, Miao-Miao Zhang, Ming-Wang Cui, Lin-Han Wu, Diwas Sunchuri, Muhammad Zia Ullah Shahid, Zhu-Ling Guo
Article Number: 170
Published online on: 16 April 2026

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Correction Open Access

[Corrigendum] MicroRNA‑122 acts as tumor suppressor by targeting TRIM29 and blocking the activity of PI3K/AKT signaling in nasopharyngeal carcinoma in vitro

Yan Yang, Qing Li, Lili Guo
Article Number: 169
Published online on: 15 April 2026

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Article Open Access

Elevated IgG levels induce an M2‑to‑M1 phenotypic shift in mucosal macrophages and restrict the growth of invasive sphenoid sinus pituitary adenomas

Xingbo Li, Zhuowei Lei, Sihan Li, Linpeng Xu, Quanji Wang, Qian Jiang, Zihan Wang, Huaqiu Zhang, Yimin Huang, Ting Lei
Article Number: 168
Published online on: 14 April 2026

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Retraction Open Access

[Retracted] SUMO1/UBC9‑decreased Nox1 activity inhibits reactive oxygen species generation and apoptosis in diabetic retinopathy

Jiaoli Hu, Pengcheng Xue, Xinbang Mao, Lin Xie, Guodong Li, Zhipeng You
Article Number: 167
Published online on: 14 April 2026

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Review Open Access

Potential for anti‑angiogenic therapy targeting the receptor for advanced glycation end products/VEGF axis in ulcerative colitis (Review)

Chen Xu, Yuting Li, Yahua Hong, Dayong Zhou, Kun He, Lianghui Wang, Feng Hong
Article Number: 166
Published online on: 09 April 2026

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Retraction Open Access

[Retracted] Molecular mechanisms underlying mangiferin‑induced apoptosis and cell cycle arrest in A549 human lung carcinoma cells

Wei Shi, Jiagang Deng, Rongsheng Tong, Yong Yang, Xia He, Jianzhen Lv, Hailian Wang, Shaoping Deng, Ping Qi, Dingding Zhang, Yi Wang
Article Number: 165
Published online on: 07 April 2026

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Mechanism of and research progress on alterations in the RET gene in thyroid cancer (Review)

Meng Wei, Rui Wang, Jincan Qian, Qiang Fang, Jun Tao
Article Number: 164
Published online on: 02 April 2026

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Review Open Access

Current research progress on extracellular vesicles derived from mesenchymal stem cells in tuberculosis treatment (Review)

Dejun Fan, Yan Yang, Li Yang
Article Number: 163
Published online on: 01 April 2026

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Article Open Access

Uremic toxin p‑cresyl sulfate enhances the calcification of aortic valvular interstitial cells via klotho/sirtuin‑1 signaling

Shao-Jung Li, Tzu-Yu Cheng, Yu-Hsun Kao, Wei-Yu Chen, Cheng-Chih Chung, Nguyen Ngoc Trang, Pao-Huan Chen, Yi-Jen Chen
Article Number: 162
Published online on: 01 April 2026

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Exercise‑induced extracellular vesicle microRNA regulates physiological function (Review)

Zhonglei Wang, Wenjue Guo, Haojia He, Yi Zhang, Na Li
Article Number: 161
Published online on: 01 April 2026

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Expression of Concern Open Access

[Expression of Concern] Electroacupuncture at GV20‑GB7 regulates mitophagy to protect against neurological deficits following intracerebral hemorrhage via inhibition of apoptosis

Ruiqiao Guan, Zhihao Li, Xiaohong Dai, Wei Zou, Xueping Yu, Hao Liu, Qiuxin Chen, Wei Teng, Peng Liu, Xiaoying Liu, Shanshan Dong
Article Number: 160
Published online on: 01 April 2026

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Review Open Access

Emerging roles of POLR2L of RNA polymerase II dynamics and disease mechanisms (Review)

Beomwoo Lee, Changgyu Son, Sunho Eom, Yuwen Li, Seon-Hwan Kim, Jongsun Park
Article Number: 159
Published online on: 30 March 2026

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Article Open Access

Combining bioinformatics prediction with experimental validation to explore the ameliorative effect of Psoralea corylifolia on vitiligo

Chen Zhang, Zhanhong Cao, Mengyang Wei, Xuanxuan Zhu, Yan Yan, Zhenhua Wang, Meng Zhang
Article Number: 158
Published online on: 30 March 2026

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Retraction Open Access

[Retracted] All‑trans‑retinoic acid inhibits chondrogenesis of rat embryo hindlimb bud mesenchymal cells by down­regulating p53 expression

Tao-Gen Zhang, Xue-Dong Li, Guo-Yong Yu, Peng Xie, Yun-Guo Wang, Zhao-Yong Liu, Quan Hong, De-Zhong Liu, Shi-Xin Du
Article Number: 157
Published online on: 30 March 2026

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Journal Cover
July-2026 Volume 34 Issue 1

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Retraction Open Access

[Retracted] Homeobox B9 facilitates hypertrophic scar formation via activating the mitogen‑activated protein kinase signaling pathway

Qun Xie, Dandan Liu, Mosheng Yu, Xiaowei Wu, Yueqiang Zhao, Qiang Hu, Qi Wang
Article Number: 196
Published online on: 18 May 2026

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Polysaccharides: Natural candidates for targeting immunometabolic regulation in hepatocellular carcinoma (Review)

Changmei Wu, Jinjin Dou, Xiwu Zhang
Article Number: 195
Published online on: 18 May 2026

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NF‑κB signaling drives Th17‑mediated lacrimal gland injury and tear dysfunction in a murine model of primary Sjögren's syndrome

Jiajun Xie, Huina Zhang, Wenyue Shen, Juan Ye
Article Number: 194
Published online on: 18 May 2026

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POSTN(+) fibroblasts and SPP1(+) macrophages in scar formation: A review of mechanisms and therapeutic targets (Review)

Haotian Wu, Xianglin Dong
Article Number: 193
Published online on: 15 May 2026

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Emerging role of DYRK1A as a target in cardiovascular diseases (Review)

Liqing Yu, Qionghong Cheng, Jun Wu
Article Number: 192
Published online on: 15 May 2026

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[Retracted] Resveratrol pretreatment attenuates traumatic brain injury in rats by suppressing NLRP3 inflammasome activation via SIRT1

Peng Zou, Xiaoxiao Liu, Gang Li, Yangang Wang
Article Number: 191
Published online on: 05 May 2026

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Gut microbiota and its metabolites: Key factors of drug resistance in the treatment of advanced prostate cancer (Review)

Jingheng Song, Hongguo Cui, Peisen Yang, Yankai Xu, Yuanyuan Liu, Gang Zhang, Yangyang Liu, Aimin Tian, Jizhong Che, Hui Sun, Zhengchao Zhang
Article Number: 190
Published online on: 04 May 2026

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Cepharanthine inhibits lysosomes and induces apoptosis in triple‑negative breast cancer cells

Juan Li, Siqin Zhou, Yu Wang, Guanghan Ou, Danli Yang, Liwen Shen
Article Number: 189
Published online on: 04 May 2026

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Review Open Access

Applications of humanized mice in Mycobacterium tuberculosis infections (Review)

Binghua Han, Fang Liu, Jinzhao Long, Jiongjiong Wang, Yange Cui, Haiyan Yang
Article Number: 188
Published online on: 04 May 2026

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Review Open Access

Research progress on neutrophil extracellular traps in sepsis‑induced coagulopathy (Review)

Jiandong Hu, Mengli Jin, Zhihua Cao, Binbin Zheng, Yuan Zheng, Hao Shen
Article Number: 187
Published online on: 04 May 2026

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Multifaceted regulatory role of proline‑ and glutamine-rich splicing factor in tumors (Review)

Shilin Zhang, Zhenhua Li, Li Fu
Article Number: 186
Published online on: 04 May 2026

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Article Open Access

Effects of ALDH2 gene expression on the oxidative stress‑mediated NF‑κB/mTOR pathway in ketamine‑induced cystitis

Xiao Jian Xi, Yong Yao, Peng Gu, Min Hao Zhang
Article Number: 185
Published online on: 04 May 2026

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Retraction Open Access

[Retracted] Rosiglitazone exerts neuroprotective effects via the suppression of neuronal autophagy and apoptosis in the cortex following traumatic brain injury

Junchao Yao, Kebin Zheng, Xiang Zhang
Article Number: 184
Published online on: 29 April 2026

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