[Corrigendum] Murine and Chinese cobra venom‑derived nerve growth factor stimulate chondrogenic differentiation of BMSCs <em>in vitro</em>: A comparative study

Miao,Zhikang; Lu,Zhenhui; Luo,Shixing; Lei,Danqing; He,Yi; Wu,Huayu; Zhao,Jinmin; Zheng,Li

doi:10.3892/mmr.2021.12444

November-2021 Volume 24 Issue 5

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November-2021 Volume 24 Issue 5

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Correction Open Access

[Corrigendum] Murine and Chinese cobra venom‑derived nerve growth factor stimulate chondrogenic differentiation of BMSCs in vitro: A comparative study

Authors:
- Zhikang Miao
- Zhenhui Lu
- Shixing Luo
- Danqing Lei
- Yi He
- Huayu Wu
- Jinmin Zhao
- Li Zheng
View Affiliations / Copyright

Affiliations: Guangxi Engineering Center in Biomedical Material for Tissue and Organ Regeneration, Guangxi Medical University, Nanning, Guangxi 530021, P.R. China, Department of Orthopedics, Ninth Affiliated Hospital of Guangxi Medical University, Beihai, Guangxi 536000, P.R. China, Life Sciences Institute, Guangxi Medical University, Nanning, Guangxi 530021, P.R. China, Department of Cell Biology and Genetics, School of Premedical Sciences, Guangxi Medical University, Nanning, Guangxi 530021, P.R. China

Copyright: © Miao et al. This is an open access article distributed under the terms of Creative Commons Attribution License [CC BY 4.0].
Article Number: 804
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Published online on: September 16, 2021

https://doi.org/10.3892/mmr.2021.12444
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Article

Mol Med Rep 18: [Related article:] 3341-3349, 2018; DOI: 10.3892/mmr.2018.9307

Subsequently to the publication of this paper, an interested reader drew to the authors’ attention that Figs. 2 and 3, showing the results from experiments designed to assess the viability of bone-derived mesenchymal stem cells culture with or without nerve growth factors (NGFs) via fluorescein diacetate/propidium iodide or H&E staining respectively, contained apparently duplicated data panels within the figures. After having examined their original data, the authors have realized that these figures were inadvertently assembled incorrectly, and that there were also misassembled data panels in Fig. 6, which showed the secretion of types I and II collagens in bone-derived mesenchymal stem cells with or without NGFs.

Figure 2.

Fluorescein diacetate/propidium iodide staining was used to detect the viability of bone-derived mesenchymal stem cells cultured alone (control) or with NGFs (mNGF, 0.06 µg/ml; cvNGF, 6 µg/ml) for 7, 14 and 21 days. Cell seeding density, 2×104/ml (original magnification, ×100; scale bar, 300 µm). cvNGF, cobra-venom-derived NGF; mNGF, murine β-NGF; NGF, nerve growth factor.

Figure 3.

Hematoxylin and eosin staining was used to detect the morphology of bone-derived mesenchymal stem cells cultured alone (control) or with NGFs (mNGF, 0.06 µg/ml; cvNGF, 6 µg/ml) for 7, 14 and 21 days. Cell seeding density, 2×104/ml (original magnification, ×100; scale bar, 300 µm). cvNGF, cobra-venom-derived NGF; mNGF, murine β-NGF; NGF, nerve growth factor.

Figure 6.

Immunohistochemical staining was used to detect the secretion of (A) type I and (B) type II collagens in bone-derived mesenchymal stem cells cultured alone (control) or with NGFs (mNGF, 0.06 µg/ml; cvNGF, 6 µg/ml) for 7, 14 and 21 days. Cell seeding density, 2×104/ml (original magnification, ×100; scale bar, 300 µm). cvNGF, cobra-venom-derived NGF; mNGF, murine β-NGF; NGF, nerve growth factor.

The corrected versions of Figs. 2, 3 and 6 are shown below and on the next page. Note that these errors did not significantly affect the results or the conclusions reported in this paper, and all the authors agree to this Corrigendum. Furthermore, the authors apologize to the readership for any inconvenience caused.