Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Molecular Medicine Reports
Join Editorial Board Propose a Special Issue
Print ISSN: 1791-2997 Online ISSN: 1791-3004
Journal Cover
January-2022 Volume 25 Issue 1

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
January-2022 Volume 25 Issue 1

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Article Open Access

Effect of therapeutic hypothermia against renal injury in a rat model of asphyxial cardiac arrest: Α focus on the survival rate, pathophysiology and antioxidant enzymes

  • Authors:
    • So Eun Kim
    • Ha-Young Shin
    • Eui-Yong Lee
    • Yeo-Jin Yoo
    • Ryun-Hee Kim
    • Jeong-Hwi Cho
    • Tae-Kyeong Lee
    • Dongchoon Ahn
    • Byung-Yong Park
    • Jae Chol Yoon
    • Seongkweon Hong
    • In-Shik Kim
    • Hyun-Jin Tae
    • Moo-Ho Won
  • View Affiliations / Copyright

    Affiliations: Department of Emergency Medicine, Research Institute of Clinical Medicine of Jeonbuk National University, Jeonju, Jeollabuk‑do 54907, Republic of Korea, College of Veterinary Medicine and Biosafety Research Institute, Jeonbuk National University, Iksan, Jeollabuk‑do 54596, Republic of Korea, Department of Biomedical Science and Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon, Gangwon‑do 24252, Republic of Korea, Department of Surgery, Kangwon National University Hospital, School of Medicine, Kangwon National University, Chuncheon, Gangwon‑do 24289, Republic of Korea, Department of Neurobiology, School of Medicine, Kangwon National University, Chuncheon, Gangwon‑do 24341, Republic of Korea
    Copyright: © Kim et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 19
    |
    Published online on: November 18, 2021
       https://doi.org/10.3892/mmr.2021.12535
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

Although multi‑organ dysfunction is associated with the survival rate following cardiac arrest (CA), the majority of studies to date have focused on hearts and brains, and few studies have considered renal failure. The objective of the present study, therefore, was to examine the effects of therapeutic hypothermia on the survival rate, pathophysiology and antioxidant enzymes in rat kidneys following asphyxial CA. Rats were sacrificed one day following CA. The survival rate, which was estimated using Kaplan‑Meier analysis, was 42.9% one day following CA. However, hypothermia, which was induced following CA, significantly increased the survival rate (71.4%). In normothermia rats with CA, the serum blood urea nitrogen level was significantly increased one day post‑CA. In addition, the serum creatinine level was significantly increased one day post‑CA. However, in CA rats exposed to hypothermia, the levels of urea nitrogen and creatinine significantly decreased following CA. Histochemical staining revealed a significant temporal increase in renal injury after the normothermia group was subjected to CA. However, renal injury was significantly decreased in the hypothermia group. Immunohistochemical analysis of the kidney revealed a significant decrease in antioxidant enzymes (copper‑zinc superoxide dismutase, manganese superoxide dismutase, glutathione peroxidase and catalase) with time in the normothermia group. However, in the hypothermia group, these enzymes were significantly elevated following CA. Collectively, the results revealed that renal dysfunction following asphyxial CA was strongly associated with the early survival rate and therapeutic hypothermia reduced renal injury via effective antioxidant mechanisms.
View Figures

Figure 1

Figure 2

Figure 3

Figure 4

Figure 5

Figure 6

View References

1 

Girotra S, Chan PS and Bradley SM: Post-resuscitation care following out-of-hospital and in-hospital cardiac arrest. Heart. 101:1943–1949. 2015. View Article : Google Scholar : PubMed/NCBI

2 

Roh YI, Jung WJ, Hwang SO, Kim S, Kim HS, Kim JH, Kim TY, Kang HS, Lee JS and Cha KC: Shorter defibrillation interval promotes successful defibrillation and resuscitation outcomes. Resuscitation. 143:100–105. 2019. View Article : Google Scholar : PubMed/NCBI

3 

Xanthos T, Iacovidou N, Pantazopoulos I, Vlachos I, Bassiakou E, Stroumpoulis K, Kouskouni E, Karabinis A and Papadimitriou L: Ischaemia-modified albumin predicts the outcome of cardiopulmonary resuscitation: An experimental study. Resuscitation. 81:591–595. 2010. View Article : Google Scholar : PubMed/NCBI

4 

Yeh ST, Cawley RJ, Aune SE and Angelos MG: Oxygen requirement during cardiopulmonary resuscitation (CPR) to effect return of spontaneous circulation. Resuscitation. 80:951–955. 2009. View Article : Google Scholar : PubMed/NCBI

5 

López-Herce J, del Castillo J, Matamoros M, Canadas S, Rodriguez-Calvo A, Cecchetti C, Rodríguez-Núnez A and Carrillo Á; Iberoamerican Pediatric Cardiac Arrest Study Network RIBEPCI, : Post return of spontaneous circulation factors associated with mortality in pediatric in-hospital cardiac arrest: A prospective multicenter multinational observational study. Crit Care. 18:6072014. View Article : Google Scholar : PubMed/NCBI

6 

Mongardon N, Dumas F, Ricome S, Grimaldi D, Hissem T, Pène F and Cariou A: Postcardiac arrest syndrome: From immediate resuscitation to long-term outcome. Ann Intensive Care. 1:452011. View Article : Google Scholar : PubMed/NCBI

7 

Neumar RW, Nolan JP, Adrie C, Aibiki M, Berg RA, Böttiger BW, Callaway C, Clark RS, Geocadin RG, Jauch EC, et al: Post-cardiac arrest syndrome: Epidemiology, pathophysiology, treatment, and prognostication. A consensus statement from the International Liaison Committee on Resuscitation (American Heart Association, Australian and New Zealand Council on Resuscitation, European Resuscitation Council, Heart and Stroke Foundation of Canada, InterAmerican Heart Foundation, Resuscitation Council of Asia, and the Resuscitation Council of Southern Africa); the American Heart Association Emergency Cardiovascular Care Committee; the Council on Cardiovascular Surgery and Anesthesia; the Council on Cardiopulmonary, Perioperative, and Critical Care; the Council on Clinical Cardiology; and the Stroke Council. Circulation. 118:2452–2483. 2008. View Article : Google Scholar : PubMed/NCBI

8 

Nolan JP, Neumar RW, Adrie C, Aibiki M, Berg RA, Böttiger BW, Callaway C, Clark RS, Geocadin RG, et al: Post-cardiac arrest syndrome: epidemiology, pathophysiology, treatment, and prognostication. A Scientific Statement from the International Liaison Committee on Resuscitation; the American Heart Association Emergency Cardiovascular Care Committee; the Council on Cardiovascular Surgery and Anesthesia; the Council on Cardiopulmonary, Perioperative, and Critical Care; the Council on Clinical Cardiology; the Council on Stroke. Resuscitation. 79:350–79. 2008.doi: 10.1016/j.resuscitation.2008.09.017. View Article : Google Scholar : PubMed/NCBI

9 

Jentzer JC, Chonde MD and Dezfulian C: Myocardial Dysfunction and shock after cardiac arrest. BioMed Res Int. 2015:3147962015. View Article : Google Scholar : PubMed/NCBI

10 

Madl C and Holzer M: Brain function after resuscitation from cardiac arrest. Curr Opin Crit Care. 10:213–217. 2004. View Article : Google Scholar : PubMed/NCBI

11 

Roberts BW, Kilgannon JH, Chansky ME, Mittal N, Wooden J, Parrillo JE and Trzeciak S: Multiple organ dysfunction after return of spontaneous circulation in postcardiac arrest syndrome. Crit Care Med. 41:1492–1501. 2013. View Article : Google Scholar : PubMed/NCBI

12 

Zeiner A, Sunder-Plassmann G, Sterz F, Holzer M, Losert H, Laggner AN and Müllner M: The effect of mild therapeutic hypothermia on renal function after cardiopulmonary resuscitation in men. Resuscitation. 60:253–261. 2004. View Article : Google Scholar : PubMed/NCBI

13 

Yanta J, Guyette FX, Doshi AA, Callaway CW and Rittenberger JC; Post Cardiac Arrest Service, : Renal dysfunction is common following resuscitation from out-of-hospital cardiac arrest. Resuscitation. 84:1371–1374. 2013. View Article : Google Scholar : PubMed/NCBI

14 

Lee JH, Lee TK, Kim IH, Lee JC, Won MH, Park JH, Ahn JH, Shin MC, Ohk TG, Moon JB, et al: Changes in histopathology and tumor necrosis factor-α levels in the hearts of rats following asphyxial cardiac arrest. Clin Exp Emerg Med. 4:160–167. 2017. View Article : Google Scholar : PubMed/NCBI

15 

Uchino S, Kellum JA, Bellomo R, Doig GS, Morimatsu H, Morgera S, Schetz M, Tan I, Bouman C, Macedo E, et al: Beginning Ending Supportive Therapy for the Kidney (BEST Kidney) Investigators Acute renal failure in critically ill patients: A multinational, multicenter study. JAMA. 294:813–818. 2005. View Article : Google Scholar : PubMed/NCBI

16 

Mattana J and Singhal PC: Prevalence and determinants of acute renal failure following cardiopulmonary resuscitation. Arch Intern Med. 153:235–239. 1993. View Article : Google Scholar : PubMed/NCBI

17 

Sachse A and Wolf G: Angiotensin II-induced reactive oxygen species and the kidney. J Am Soc Nephrol. 18:2439–2446. 2007. View Article : Google Scholar : PubMed/NCBI

18 

Baud L and Ardaillou R: Reactive oxygen species: Production and role in the kidney. Am J Physiol. 251:F765–F776. 1986.PubMed/NCBI

19 

Rodrigo R, Fernández-Gajardo R, Gutiérrez R, Matamala JM, Carrasco R, Miranda-Merchak A and Feuerhake W: Oxidative stress and pathophysiology of ischemic stroke: Novel therapeutic opportunities. CNS Neurol Disord Drug Targets. 12:698–714. 2013. View Article : Google Scholar : PubMed/NCBI

20 

Shahzad S, Hasan A, Faizy AF, Mateen S, Fatima N and Moin S: Elevated DNA damage, oxidative stress, and impaired response defense system inflicted in patients with myocardial infarction. Clin Appl Thromb Hemost. 24:780–789. 2018. View Article : Google Scholar : PubMed/NCBI

21 

Hackenhaar FS, Medeiros TM, Heemann FM, Behling CS, Putti JS, Mahl CD, Verona C, da Silva ACA, Guerra MC, Gonçalves CAS, et al: Therapeutic hypothermia reduces oxidative damage and alters antioxidant defenses after cardiac arrest. Oxid Med Cell Longev. 2017:87043522017. View Article : Google Scholar : PubMed/NCBI

22 

Jawad A, Yoo YJ, Cho JH, Yoon JC, Tian W, Islam MS, Lee EY, Shin HY, Kim SE, Kim K, et al: Therapeutic hypothermia effect on asphyxial cardiac arrest-induced renal ischemia/reperfusion injury via change of Nrf2/HO-1 levels. Exp Ther Med. 22:10312021. View Article : Google Scholar : PubMed/NCBI

23 

Islam A, Kim SE, Yoon JC, Jawad A, Tian W, Yoo YJ, Kim IS, Ahn D, Park BY, Hwang Y, et al: Protective effects of therapeutic hypothermia on renal injury in an asphyxial cardiac arrest rat model. J Therm Biol. 94:1027612020. View Article : Google Scholar : PubMed/NCBI

24 

Drabek T, Janata A, Wilson CD, Stezoski J, Janesko-Feldman K, Tisherman SA, Foley LM, Verrier JD and Kochanek PM: Minocycline attenuates brain tissue levels of TNF-α produced by neurons after prolonged hypothermic cardiac arrest in rats. Resuscitation. 85:284–291. 2014. View Article : Google Scholar : PubMed/NCBI

25 

Han F, Boller M, Guo W, Merchant RM, Lampe JW, Smith TM and Becker LB: A rodent model of emergency cardiopulmonary bypass resuscitation with different temperatures after asphyxial cardiac arrest. Resuscitation. 81:93–99. 2010. View Article : Google Scholar : PubMed/NCBI

26 

Che D, Li L, Kopil CM, Liu Z, Guo W and Neumar RW: Impact of therapeutic hypothermia onset and duration on survival, neurologic function, and neurodegeneration after cardiac arrest. Crit Care Med. 39:1423–1430. 2011. View Article : Google Scholar : PubMed/NCBI

27 

Park Y, Ahn JH, Cho JH, Tae HJ, Lee TK, Kim B, Lee JC, Park JH, Shin MC, Ohk TG, et al: Effects of hypothermia on inflammatory cytokine expression in rat liver following asphyxial cardiac arrest. Exp Ther Med. 21:6262021. View Article : Google Scholar : PubMed/NCBI

28 

Varming K, Forsum U, Bruunshuus I and Olesen H: International Federation of Clinical Chemistry and Laboratory Medicine: Scientific Division. EJIFCC. 15:10–13. 2004.PubMed/NCBI

29 

Nam SM, Kim JW, Yoo DY, Choi JH, Kim W, Jung HY, Won MH, Hwang IK, Seong JK and Yoon YS: Effects of treadmill exercise on neural stem cells, cell proliferation, and neuroblast differentiation in the subgranular zone of the dentate gyrus in cyclooxygenase-2 knockout mice. Neurochem Res. 38:2559–2569. 2013. View Article : Google Scholar : PubMed/NCBI

30 

Duarte CG, Zhang J and Ellis S: Effects of radiocontrast and endothelin administration on systolic blood pressure and renal damage in male spontaneously hypertensive and Wistar Kyoto rats with phentolamine-induced adrenergic blockade. Invest Radiol. 33:104–112. 1998. View Article : Google Scholar : PubMed/NCBI

31 

Raij L, Azar S and Keane W: Mesangial immune injury, hypertension, and progressive glomerular damage in Dahl rats. Kidney Int. 26:137–143. 1984. View Article : Google Scholar : PubMed/NCBI

32 

Slaughter TN, Paige A, Spires D, Kojima N, Kyle PB, Garrett MR, Roman RJ and Williams JM: Characterization of the development of renal injury in Type-1 diabetic Dahl salt-sensitive rats. Am J Physiol Regul Integr Comp Physiol. 305:R727–R734. 2013. View Article : Google Scholar : PubMed/NCBI

33 

Canales BK, Reyes L, Reinhard MK, Khan SR, Goncalves CG and Meguid MM: Renal glomerular and tubular injury after gastric bypass in obese rats. Nutrition. 28:76–80. 2012. View Article : Google Scholar : PubMed/NCBI

34 

Kang DH, Kim YG, Andoh TF, Gordon KL, Suga S, Mazzali M, Jefferson JA, Hughes J, Bennett W, Schreiner GF, et al: Post-cyclosporine-mediated hypertension and nephropathy: Amelioration by vascular endothelial growth factor. Am J Physiol Renal Physiol. 280:F727–F736. 2001. View Article : Google Scholar : PubMed/NCBI

35 

Açıkgöz Ş, Edebali N, Barut F, Can M, Tekin İÖ, Büyükuysal Ç and Açıkgöz B: Ischemia modified albumin increase indicating cardiac damage after experimental subarachnoid hemorrhage. BMC Neurosci. 15:332014. View Article : Google Scholar : PubMed/NCBI

36 

Klopfleisch R: Multiparametric and semiquantitative scoring systems for the evaluation of mouse model histopathology - a systematic review. BMC Vet Res. 9:1232013. View Article : Google Scholar : PubMed/NCBI

37 

Li J, Jiang H, Wu P, Li S, Han B, Yang Q, Wang X, Han B, Deng N, Qu B, et al: Toxicological effects of deltamethrin on quail cerebrum: Weakened antioxidant defense and enhanced apoptosis. Environ Pollut. 286:1173192021. View Article : Google Scholar : PubMed/NCBI

38 

Yang D, Yang Q, Fu N, Li S, Han B, Liu Y, Tang Y, Guo X, Lv Z and Zhang Z: Hexavalent chromium induced heart dysfunction via Sesn2-mediated impairment of mitochondrial function and energy supply. Chemosphere. 264:1285472021. View Article : Google Scholar : PubMed/NCBI

39 

Nguyen Thi PA, Chen MH, Li N, Zhuo XJ and Xie L: PD98059 protects brain against cells death resulting from ROS/ERK activation in a cardiac arrest rat model. Oxid Med Cell Longev. 2016:37237622016. View Article : Google Scholar : PubMed/NCBI

40 

Yin XL, Shen H, Zhang W and Yang Y: Inhibition of endoplasm reticulum stress by anisodamine protects against myocardial injury after cardiac arrest and resuscitation in rats. Am J Chin Med. 39:853–866. 2011. View Article : Google Scholar : PubMed/NCBI

41 

Chou AH, Lee CM, Chen CY, Liou JT, Liu FC, Chen YL and Day YJ: Hippocampal transcriptional dysregulation after renal ischemia and reperfusion. Brain Res. 1582:197–210. 2014. View Article : Google Scholar : PubMed/NCBI

42 

Schuck PF, Alves L, Pettenuzzo LF, Felisberto F, Rodrigues LB, Freitas BW, Petronilho F, Dal-Pizzol F, Streck EL and Ferreira GC: Acute renal failure potentiates methylmalonate-induced oxidative stress in brain and kidney of rats. Free Radic Res. 47:233–240. 2013. View Article : Google Scholar : PubMed/NCBI

43 

Wang CH, Chang WT, Tsai MS, Huang CH and Chen WJ: Synergistic effects of moderate therapeutic hypothermia and levosimendan on cardiac function and survival after asphyxia-induced cardiac arrest in rats. J Am Heart Assoc. 9:e0161392020. View Article : Google Scholar : PubMed/NCBI

44 

Safar PJ and Kochanek PM: Therapeutic hypothermia after cardiac arrest. N Engl J Med. 346:612–613. 2002. View Article : Google Scholar : PubMed/NCBI

45 

Tujjar O, Mineo G, Dell'Anna A, Poyatos-Robles B, Donadello K, Scolletta S, Vincent JL and Taccone FS: Acute kidney injury after cardiac arrest. Crit Care. 19:1692015. View Article : Google Scholar : PubMed/NCBI

46 

Ribeiro GB, Santos EBD, Bona SR, Schaefer PG, Garcez TA, Rabolini EB, Smaniotto GP, Marroni NP and Corso CO: The effects of local ischemic preconditioning and topical hypothermia in renal ischemia/reperfusion injury in rats. Acta Cir Bras. 32:816–826. 2017. View Article : Google Scholar : PubMed/NCBI

47 

Tissier R, Giraud S, Quellard N, Fernandez B, Lidouren F, Darbera L, Kohlhauer M, Pons S, Chenoune M, Bruneval P, et al: Kidney protection by hypothermic total liquid ventilation after cardiac arrest in rabbits. Anesthesiology. 120:861–869. 2014. View Article : Google Scholar : PubMed/NCBI

48 

Bleske BE, Song J, Chow MS, Kluger J and White CM: Hematologic and chemical changes observed during and after cardiac arrest in a canine model - a pilot study. Pharmacotherapy. 21:1187–1191. 2001. View Article : Google Scholar : PubMed/NCBI

49 

Hang CC, Li CS, Wu CJ and Yang J: Acute kidney injury after cardiac arrest of ventricular fibrillation and asphyxiation swine model. Am J Emerg Med. 32:208–215. 2014. View Article : Google Scholar : PubMed/NCBI

50 

Souza PC, Santos EBD, Motta GL, Bona SR, Schaefer PG, Campagnol D, Bortolini T and Corso CO: Combined effects of melatonin and topical hypothermia on renal ischemia-reperfusion injury in rats. Acta Cir Bras. 33:197–206. 2018. View Article : Google Scholar : PubMed/NCBI

51 

Tae HJ, Park JH, Cho JH, Kim IH, Ahn JH, Lee JC, Kim JD, Park J, Choi SY and Won MH: Oenanthe javanica extract increases immunoreactivities of antioxidant enzymes in the rat kidney. Chin Med J (Engl). 127:3758–3763. 2014.PubMed/NCBI

52 

Sehitoglu MH, Karaboga I, Kiraz A and Kiraz HA: The hepatoprotective effect of Aloe vera on ischemia-reperfusion injury in rats. North Clin Istanb. 6:203–209. 2018.PubMed/NCBI

53 

Xia Z, Wang W, Xiao Q, Ye Q, Zhang X and Wang Y: Mild hypothermia protects renal function in ischemia-reperfusion kidney: an experimental study in mice. Transplant Proc. 50:3816–3821. 2018. View Article : Google Scholar : PubMed/NCBI

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Kim SE, Shin H, Lee E, Yoo Y, Kim R, Cho J, Lee T, Ahn D, Park B, Yoon JC, Yoon JC, et al: Effect of therapeutic hypothermia against renal injury in a rat model of asphyxial cardiac arrest: Α focus on the survival rate, pathophysiology and antioxidant enzymes. Mol Med Rep 25: 19, 2022.
APA
Kim, S.E., Shin, H., Lee, E., Yoo, Y., Kim, R., Cho, J. ... Won, M. (2022). Effect of therapeutic hypothermia against renal injury in a rat model of asphyxial cardiac arrest: Α focus on the survival rate, pathophysiology and antioxidant enzymes. Molecular Medicine Reports, 25, 19. https://doi.org/10.3892/mmr.2021.12535
MLA
Kim, S. E., Shin, H., Lee, E., Yoo, Y., Kim, R., Cho, J., Lee, T., Ahn, D., Park, B., Yoon, J. C., Hong, S., Kim, I., Tae, H., Won, M."Effect of therapeutic hypothermia against renal injury in a rat model of asphyxial cardiac arrest: Α focus on the survival rate, pathophysiology and antioxidant enzymes". Molecular Medicine Reports 25.1 (2022): 19.
Chicago
Kim, S. E., Shin, H., Lee, E., Yoo, Y., Kim, R., Cho, J., Lee, T., Ahn, D., Park, B., Yoon, J. C., Hong, S., Kim, I., Tae, H., Won, M."Effect of therapeutic hypothermia against renal injury in a rat model of asphyxial cardiac arrest: Α focus on the survival rate, pathophysiology and antioxidant enzymes". Molecular Medicine Reports 25, no. 1 (2022): 19. https://doi.org/10.3892/mmr.2021.12535
Copy and paste a formatted citation
x
Spandidos Publications style
Kim SE, Shin H, Lee E, Yoo Y, Kim R, Cho J, Lee T, Ahn D, Park B, Yoon JC, Yoon JC, et al: Effect of therapeutic hypothermia against renal injury in a rat model of asphyxial cardiac arrest: Α focus on the survival rate, pathophysiology and antioxidant enzymes. Mol Med Rep 25: 19, 2022.
APA
Kim, S.E., Shin, H., Lee, E., Yoo, Y., Kim, R., Cho, J. ... Won, M. (2022). Effect of therapeutic hypothermia against renal injury in a rat model of asphyxial cardiac arrest: Α focus on the survival rate, pathophysiology and antioxidant enzymes. Molecular Medicine Reports, 25, 19. https://doi.org/10.3892/mmr.2021.12535
MLA
Kim, S. E., Shin, H., Lee, E., Yoo, Y., Kim, R., Cho, J., Lee, T., Ahn, D., Park, B., Yoon, J. C., Hong, S., Kim, I., Tae, H., Won, M."Effect of therapeutic hypothermia against renal injury in a rat model of asphyxial cardiac arrest: Α focus on the survival rate, pathophysiology and antioxidant enzymes". Molecular Medicine Reports 25.1 (2022): 19.
Chicago
Kim, S. E., Shin, H., Lee, E., Yoo, Y., Kim, R., Cho, J., Lee, T., Ahn, D., Park, B., Yoon, J. C., Hong, S., Kim, I., Tae, H., Won, M."Effect of therapeutic hypothermia against renal injury in a rat model of asphyxial cardiac arrest: Α focus on the survival rate, pathophysiology and antioxidant enzymes". Molecular Medicine Reports 25, no. 1 (2022): 19. https://doi.org/10.3892/mmr.2021.12535
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team