Behavioral tests for evaluating the characteristics of brain diseases in rodent models: Optimal choices for improved outcomes (Review)

  • Authors:
    • Lingyi Huang
    • Dongqiong Xiao
    • Hao Sun
    • Yi Qu
    • Xiaojuan Su
  • View Affiliations

  • Published online on: March 28, 2022     https://doi.org/10.3892/mmr.2022.12699
  • Article Number: 183
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Abstract

Behavioral assessment is the dominant approach for evaluating whether animal models of brain diseases can successfully mimic the clinical characteristics of diseases. At present, most research regarding brain diseases involves the use of rodent models. While studies have reported numerous methods of behavioral assessments in rodent models of brain diseases, each with different principles, procedures, and assessment criteria, only few reviews have focused on characterizing and differentiating these methods based on applications for which they are most appropriate. Therefore, in the present review, the representative behavioral tests in rodent models of brain diseases were compared and differentiated, aiming to provide convenience for researchers in selecting the optimal methods for their studies.
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May-2022
Volume 25 Issue 5

Print ISSN: 1791-2997
Online ISSN:1791-3004

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Copy and paste a formatted citation
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Spandidos Publications style
Huang L, Xiao D, Sun H, Qu Y and Su X: Behavioral tests for evaluating the characteristics of brain diseases in rodent models: Optimal choices for improved outcomes (Review). Mol Med Rep 25: 183, 2022
APA
Huang, L., Xiao, D., Sun, H., Qu, Y., & Su, X. (2022). Behavioral tests for evaluating the characteristics of brain diseases in rodent models: Optimal choices for improved outcomes (Review). Molecular Medicine Reports, 25, 183. https://doi.org/10.3892/mmr.2022.12699
MLA
Huang, L., Xiao, D., Sun, H., Qu, Y., Su, X."Behavioral tests for evaluating the characteristics of brain diseases in rodent models: Optimal choices for improved outcomes (Review)". Molecular Medicine Reports 25.5 (2022): 183.
Chicago
Huang, L., Xiao, D., Sun, H., Qu, Y., Su, X."Behavioral tests for evaluating the characteristics of brain diseases in rodent models: Optimal choices for improved outcomes (Review)". Molecular Medicine Reports 25, no. 5 (2022): 183. https://doi.org/10.3892/mmr.2022.12699