Journal Articles

Article Open Access

Copy number alterations and epithelial‑mesenchymal transition genes in diffuse and intestinal gastric cancers in Mexican patients

Violeta Larios-Serrato, José-Darío Martínez‑Ezquerro, Hilda-Alicia Valdez‑Salazar, Javier Torres, Margarita Camorlinga‑Ponce, Patricia Piña‑Sánchez, Martha-Eugenia Ruiz‑Tachiquín

Article Number: 191 Published online on: 31 March 2022
Article Open Access

Salivary microbiota analysis of patients with membranous nephropathy

Shaodong Luan, Shuyuan Zhang, Litao Pan, Wenjun Hu, Haihong Cui, Xing Wei, Renyong Lin, Chundi Li, Ping Zeng, Xi Wang, Weilong Li, Zigan Xu, Yingwei Zhang, Bo Hu, Hanchao Gao

Article Number: 190 Published online on: 31 March 2022
Article Open Access

Interferon regulatory factor 5‑induced upregulation of zinc‑finger protein 217 promotes pancreatic carcinoma progression

Xiao Qiao, Shengxiang Lv, Yan Qiao, Fei Wang, Lin Miao

Article Number: 189 Published online on: 30 March 2022
Article Open Access

Protection against ulcerative colitis and colorectal cancer by evodiamine via anti‑inflammatory effects

Yongfeng Zhang, Yaqin Zhang, Yang Zhao, Wanyue Wu, Weiqi Meng, Yulin Zhou, Ye Qiu, Chenliang Li

Article Number: 188 Published online on: 29 March 2022
Article

Dynamic detection of HER2 of circulating tumor cells in patients with gastric carcinoma and its clinical application

Hongjian Zhao, Chunyan Huang, Mei Lin, Mingqing Zhou, Chunjin Huang

Article Number: 187 Published online on: 28 March 2022
Article Open Access

Circulating microRNA‑423 attenuates the phosphorylation of calcium handling proteins in atrial fibrillation

Hyewon Park, Hyelim Park, Junbeom Park

Article Number: 186 Published online on: 28 March 2022
Article Open Access

CTRP9 decreases high glucose‑induced trophoblast cell damage by reducing endoplasmic reticulum stress

Lianxiao Zhang, Huiqing Ding, Yubo Shi, Duoyi Zhang, Xue Yang

Article Number: 185 Published online on: 28 March 2022
Article Open Access

Salvianolic acid B acts against non‑small cell lung cancer A549 cells via inactivation of the MAPK and Smad2/3 signaling pathways

Guanglei Han, Yongzhong Wang, Tong Liu, Jiarong Gao, Fengyi Duan, Ming Chen, Yan Yang, Chao Wu

Article Number: 184 Published online on: 28 March 2022
Review

Behavioral tests for evaluating the characteristics of brain diseases in rodent models: Optimal choices for improved outcomes (Review)

Lingyi Huang, Dongqiong Xiao, Hao Sun, Yi Qu, Xiaojuan Su

Article Number: 183 Published online on: 28 March 2022
Article Open Access

Whole body vibration remodels skeletal muscle via autophagy and energy metabolism in diabetic mice

Shanshan An, Dahao Wang, Xue Ma, Chang Liu

Article Number: 182 Published online on: 23 March 2022
Article Open Access

Aspirin attenuates liver fibrosis by suppressing TGF‑β1/Smad signaling

Yimin Sun, Bingyan Liu, Jianping Xie, Xuefeng Jiang, Baolai Xiao, Xiaomiao Hu, Jinjian Xiang

Article Number: 181 Published online on: 23 March 2022
Article Open Access

Piceatannol suppresses inflammation and promotes apoptosis in rheumatoid arthritis‑fibroblast‑like synoviocytes by inhibiting the NF‑κB and MAPK signaling pathways

Xuezhong Gao, Xiaodiao Kang, Hongwei Lu, Enxing Xue, Rong Chen, Jun Pan, Jianfeng Ma

Article Number: 180 Published online on: 22 March 2022
Article Open Access

lncRNA LINC00284 promotes nucleus pulposus cell proliferation and ECM synthesis via regulation of the miR‑205‑3p/Wnt/β‑catenin axis

Min Zhu, Xiaoling Yan, Yin Zhao, Huawei Xue, Zhen Wang, Bo Wu, Xiangyang Li, Yixin Shen

Article Number: 179 Published online on: 22 March 2022
Article Open Access

Ginsenoside Rg1 exerts anti‑apoptotic effects on non‑alcoholic fatty liver cells by downregulating the expression of SGPL1

Guiming Li, Hongqing Xie, Xiaodie Cao, Chong Ma, Yan Li, Li Chen

Article Number: 178 Published online on: 22 March 2022
Article

Long non‑coding RNA MALAT1 is involved in retinal pigment epithelial cell damage caused by high glucose treatment

Xinli Jiang, Yan Liu, Yuling Wang, Yaru Zhou, Huipeng Miao, Peng Zhang, Jingxue Ma

Article Number: 177 Published online on: 21 March 2022
Article Open Access

Role and mechanism of the lncRNA SNHG1/miR‑450b‑5p/IGF1 axis in the regulation of myocardial ischemia reperfusion injury

Junfeng Zhan, Qiulin Yin, Peng Zhao, Lang Hong

Article Number: 176 Published online on: 21 March 2022
Correction Open Access

[Corrigendum] Metformin reverses multidrug resistance in human hepatocellular carcinoma Bel‑7402/5‑fluorouracil cells

Sunbin Ling, Yu Tian, Haiquan Zhang, Kaiqi Jia, Tingting Feng, Deguang Sun, Zhenming Gao, Fei Xu, Zhaoyuan Hou, Yan Li, Liming Wang

Article Number: 175 Published online on: 21 March 2022
Article Open Access

HOXB2 increases the proliferation and invasiveness of colon cancer cells through the upregulation of CCT6A

Xuelian Yang, Yuanhe Tong, Wenxia Ye, Lifen Chen

Article Number: 174 Published online on: 18 March 2022
Article Open Access

Reparative effects of chronic intermittent hypobaric hypoxia pre‑treatment on intervertebral disc degeneration in rats

Shu-Ren Liu, Dong Ren, Hao-Tan Wu, Shuang-Quan Yao, Zhao-Hui Song, Lin-Dan Geng, Peng-Cheng Wang

Article Number: 173 Published online on: 18 March 2022
Article Open Access

Taurine attenuates ER stress‑associated apoptosis and catabolism in nucleus pulposus cells

Liuxie Yang, Zhenhuan Li, Yueping Ouyang

Article Number: 172 Published online on: 18 March 2022
Review Open Access

Insights into the role of STAT3 in intrahepatic cholangiocarcinoma (Review)

Ranzhiqiang Yang, Yinghui Song, Kashif Shakoor, Weimin Yi, Chuang Peng, Sulai Liu

Article Number: 171 Published online on: 17 March 2022
Article Open Access

Sigma‑1 receptor overexpression promotes proliferation and ameliorates cell apoptosis in β‑cells

Mengting Ke, Fengping Lin, Huawei Wang, Guangzhen He, Jieyuan Feng, Linyang Song, Yancheng Xu, Jie Liu

Article Number: 170 Published online on: 17 March 2022
Review Open Access

Interactions of circRNAs with methylation: An important aspect of circRNA biogenesis and function (Review)

Chunlei Zhang, Han Cui, Chuang Huang, Feiyan Kong, Qi Yang, Pengcheng Miao, Zhigang Cao, Weijun Zhang, Dehui Chang

Article Number: 169 Published online on: 16 March 2022
Article Open Access

E. coli JM83 damages the mucosal barrier in Ednrb knockout mice to promote the development of Hirschsprung‑associated enterocolitis via activation of TLR4/p‑p38/NF‑κB signaling

Zebing Zheng, Mingjuan Gao, Chengyan Tang, Lu Huang, Yuan Gong, Yuanmei Liu, Jian Wang

Article Number: 168 Published online on: 16 March 2022
Article

Atorvastatin regulates vascular smooth muscle cell phenotypic transformation by epigenetically modulating contractile proteins and mediating Akt/FOXO4 axis

Xinping Du, Zhiyuan Sun, Zhongnan Cao, Xiuhong Zhou, Dong Wang, Kuan Wang, Xuebin Li, Guoxing Zuo

Article Number: 167 Published online on: 16 March 2022
Review Open Access

The role of galectins‑1, 3, 7, 8 and 9 as potential diagnostic and therapeutic markers in ovarian cancer (Review)

Aleksandra Mielczarek‑Palacz, Zdzisława Kondera‑Anasz, Marta Smycz‑Kubańska, Aleksandra Englisz, Aleksandra Janusz, Patrycja Królewska‑Daszczyńska, Dominika Wendlocha

Article Number: 166 Published online on: 15 March 2022
Article Open Access

Preserving mitochondrial function by inhibiting GRP75 ameliorates neuron injury under ischemic stroke

Bin Wen, Kai Xu, Rui Huang, Teng Jiang, Jian Wang, Jiehui Chen, Juan Chen, Benhong He

Article Number: 165 Published online on: 15 March 2022
Article Open Access

KLF4 downregulates FGF21 to activate inflammatory injury and oxidative stress of LPS‑induced ATDC5 cells via SIRT1/NF‑κB/p53 signaling

Xi Chen, Jia Wen, Chaoqi Liu, Donggeng Guo

Article Number: 164 Published online on: 14 March 2022
Correction Open Access

[Corrigendum] Type II cGMP‑dependent protein kinase inhibits the migration, invasion and proliferation of several types of human cancer cells

Min Wu, Yan Wu, Hai Qian, Yan Tao, Ji Pang, Ying Wang, Yongchang Chen

Article Number: 163 Published online on: 14 March 2022
Article Open Access

Potential impact of GCK, MIR-196A-2 and MIR-423 gene abnormalities on the development and progression of type 2 diabetes mellitus in Asir and Tabuk regions of Saudi Arabia

Mohammad Muzaffar Mir, Rashid Mir, Mushabab Ayed Abdullah Alghamdi, Javed Iqbal Wani, Imadeldin Elfaki, Zia Ul Sabah, Muhanad Alhujaily, Mohammed Jeelani, Vijaya Marakala, Muffarah Hamid Alharthi, Abdullah M. Al‑Shahrani

Article Number: 162 Published online on: 14 March 2022
Article Open Access

SESN1 attenuates the Ox‑LDL‑induced inflammation, apoptosis and endothelial‑mesenchymal transition of human umbilical vein endothelial cells by regulating AMPK/SIRT1/LOX1 signaling

Feng Gao, Yongcheng Zhao, Bin Zhang, Chunwei Xiao, Zhanfa Sun, Yuan Gao, Xueyong Dou

Article Number: 161 Published online on: 11 March 2022
Article Open Access

P2X7 receptor knockdown suppresses osteoclast differentiation by inhibiting autophagy and Ca2+/calcineurin signaling

Yonggang Ma, Ran Di, Hongyan Zhao, Ruilong Song, Hui Zou, Zongping Liu

Article Number: 160 Published online on: 10 March 2022
Article Open Access

Differential immunohistochemical expression of DEC1, CK‑1ε, and CD44 in oral atypical squamous epithelium and carcinoma in situ

Fuyuki Sato, Ujjal K. Bhawal, Shoko Osaki, Nao Sugiyama, Kosuke Oikawa, Yasuteru Muragaki

Article Number: 159 Published online on: 10 March 2022
Article Open Access

Τelomerase inhibitors and activators in aging and cancer: A systematic review

Persefoni Fragkiadaki, Elisavet Renieri, Katerina Kalliantasi, Elisavet Kouvidi, Evita Apalaki, Elena Vakonaki, Charalampos Mamoulakis, Demetrios A. Spandidos, Aristidis Tsatsakis

Article Number: 158 Published online on: 08 March 2022
Retraction Open Access

[Retracted] MicroRNA‑181 serves an oncogenic role in breast cancer via the inhibition of SPRY4

Yifu Tian, Xiaodan Fu, Qingling Li, Ying Wang, Dan Fan, Qin Zhou, Weilu Kuang, Liangfang Shen

Article Number: 157 Published online on: 04 March 2022
Article Open Access

Co‑expressed microRNAs, target genes and pathways related to metabolism, inflammation and endocrine function in individuals at risk for type 2 diabetes

Elena Flowers, Kesava Asam, Isabel Elaine Allen, Alka M. Kanaya, Bradley E. Aouizerat

Article Number: 156 Published online on: 03 March 2022
Article Open Access

CID16020046, a GPR55 antagonist, attenuates sepsis‑induced acute kidney injury

Rongxin Chen, Hailin Xu, Zebin Guo, Peng Zhang, Jianxia Chen, Zheng Chen

Article Number: 155 Published online on: 03 March 2022
Article Open Access

The GABAB receptor agonist STX209 reverses the autism‑like behaviour in an animal model of autism induced by prenatal exposure to valproic acid

Shucai Jiang, Lifei Xiao, Yu Sun, Maotao He, Caibin Gao, Changliang Zhu, Haigang Chang, Jiangwei Ding, Wenchao Li, Yangyang Wang, Tao Sun, Feng Wang

Article Number: 154 Published online on: 02 March 2022
Article Open Access

A novel non‑selective atypical PKC agonist could protect neuronal cell line from Aβ‑oligomer induced toxicity by suppressing Aβ generation

Dongmei Zou, Qian Li, Wenyang Pan, Peng Chen, Miao Sun, Xiaofeng Bao

Article Number: 153 Published online on: 02 March 2022
Article

Exosome‑derived lncRNA‑Ankrd26 promotes dental pulp restoration by regulating miR‑150‑TLR4 signaling

Lin Li, Jianping Ge

Article Number: 152 Published online on: 02 March 2022
Review

Potential clinical applications of alpha‑ketoglutaric acid in diseases (Review)

Xingqi Meng, Huiqing Liu, Lixuan Peng, Weiguo He, Suyun Li

Article Number: 151 Published online on: 02 March 2022
Article

USP22 promotes pro‑inflammatory responses in Pseudomonas aeruginosa‑induced keratitis by targeting TRAF6

Di Chen, Dawei Song, Yibin Ma, Weizhao Lu, Jianfeng Qiu, Yi Wang

Article Number: 149 Published online on: 02 March 2022
Journal Cover

May-2022
Volume 25 Issue 5

Print ISSN: 1791-2997
Online ISSN: 1791-3004

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