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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
May-2022 Volume 25 Issue 5

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Journal Metrics

Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

Copy number alterations and epithelial‑mesenchymal transition genes in diffuse and intestinal gastric cancers in Mexican patients

Violeta Larios-Serrato, José-Darío Martínez‑Ezquerro, Hilda-Alicia Valdez‑Salazar, Javier Torres, Margarita Camorlinga‑Ponce, Patricia Piña‑Sánchez, Martha-Eugenia Ruiz‑Tachiquín
Article Number: 191
Published online on: 31 March 2022

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Article Open Access

Salivary microbiota analysis of patients with membranous nephropathy

Shaodong Luan, Shuyuan Zhang, Litao Pan, Wenjun Hu, Haihong Cui, Xing Wei, Renyong Lin, Chundi Li, Ping Zeng, Xi Wang, Weilong Li, Zigan Xu, Yingwei Zhang, Bo Hu, Hanchao Gao
Article Number: 190
Published online on: 31 March 2022

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Article Open Access

Interferon regulatory factor 5‑induced upregulation of zinc‑finger protein 217 promotes pancreatic carcinoma progression

Xiao Qiao, Shengxiang Lv, Yan Qiao, Fei Wang, Lin Miao
Article Number: 189
Published online on: 30 March 2022

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Article Open Access

Protection against ulcerative colitis and colorectal cancer by evodiamine via anti‑inflammatory effects

Yongfeng Zhang, Yaqin Zhang, Yang Zhao, Wanyue Wu, Weiqi Meng, Yulin Zhou, Ye Qiu, Chenliang Li
Article Number: 188
Published online on: 29 March 2022

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Article

Dynamic detection of HER2 of circulating tumor cells in patients with gastric carcinoma and its clinical application

Hongjian Zhao, Chunyan Huang, Mei Lin, Mingqing Zhou, Chunjin Huang
Article Number: 187
Published online on: 28 March 2022

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Article Open Access

Circulating microRNA‑423 attenuates the phosphorylation of calcium handling proteins in atrial fibrillation

Hyewon Park, Hyelim Park, Junbeom Park
Article Number: 186
Published online on: 28 March 2022

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Article Open Access

CTRP9 decreases high glucose‑induced trophoblast cell damage by reducing endoplasmic reticulum stress

Lianxiao Zhang, Huiqing Ding, Yubo Shi, Duoyi Zhang, Xue Yang
Article Number: 185
Published online on: 28 March 2022

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Article Open Access

Salvianolic acid B acts against non‑small cell lung cancer A549 cells via inactivation of the MAPK and Smad2/3 signaling pathways

Guanglei Han, Yongzhong Wang, Tong Liu, Jiarong Gao, Fengyi Duan, Ming Chen, Yan Yang, Chao Wu
Article Number: 184
Published online on: 28 March 2022

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Review

Behavioral tests for evaluating the characteristics of brain diseases in rodent models: Optimal choices for improved outcomes (Review)

Lingyi Huang, Dongqiong Xiao, Hao Sun, Yi Qu, Xiaojuan Su
Article Number: 183
Published online on: 28 March 2022

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Article Open Access

Whole body vibration remodels skeletal muscle via autophagy and energy metabolism in diabetic mice

Shanshan An, Dahao Wang, Xue Ma, Chang Liu
Article Number: 182
Published online on: 23 March 2022

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Article Open Access

Aspirin attenuates liver fibrosis by suppressing TGF‑β1/Smad signaling

Yimin Sun, Bingyan Liu, Jianping Xie, Xuefeng Jiang, Baolai Xiao, Xiaomiao Hu, Jinjian Xiang
Article Number: 181
Published online on: 23 March 2022

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Article Open Access

Piceatannol suppresses inflammation and promotes apoptosis in rheumatoid arthritis‑fibroblast‑like synoviocytes by inhibiting the NF‑κB and MAPK signaling pathways

Xuezhong Gao, Xiaodiao Kang, Hongwei Lu, Enxing Xue, Rong Chen, Jun Pan, Jianfeng Ma
Article Number: 180
Published online on: 22 March 2022

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Article Open Access

lncRNA LINC00284 promotes nucleus pulposus cell proliferation and ECM synthesis via regulation of the miR‑205‑3p/Wnt/β‑catenin axis

Min Zhu, Xiaoling Yan, Yin Zhao, Huawei Xue, Zhen Wang, Bo Wu, Xiangyang Li, Yixin Shen
Article Number: 179
Published online on: 22 March 2022

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Article Open Access

Ginsenoside Rg1 exerts anti‑apoptotic effects on non‑alcoholic fatty liver cells by downregulating the expression of SGPL1

Guiming Li, Hongqing Xie, Xiaodie Cao, Chong Ma, Yan Li, Li Chen
Article Number: 178
Published online on: 22 March 2022

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Article

Long non‑coding RNA MALAT1 is involved in retinal pigment epithelial cell damage caused by high glucose treatment

Xinli Jiang, Yan Liu, Yuling Wang, Yaru Zhou, Huipeng Miao, Peng Zhang, Jingxue Ma
Article Number: 177
Published online on: 21 March 2022

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Article Open Access

Role and mechanism of the lncRNA SNHG1/miR‑450b‑5p/IGF1 axis in the regulation of myocardial ischemia reperfusion injury

Junfeng Zhan, Qiulin Yin, Peng Zhao, Lang Hong
Article Number: 176
Published online on: 21 March 2022

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Correction Open Access

[Corrigendum] Metformin reverses multidrug resistance in human hepatocellular carcinoma Bel‑7402/5‑fluorouracil cells

Sunbin Ling, Yu Tian, Haiquan Zhang, Kaiqi Jia, Tingting Feng, Deguang Sun, Zhenming Gao, Fei Xu, Zhaoyuan Hou, Yan Li, Liming Wang
Article Number: 175
Published online on: 21 March 2022

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Article Open Access

HOXB2 increases the proliferation and invasiveness of colon cancer cells through the upregulation of CCT6A

Xuelian Yang, Yuanhe Tong, Wenxia Ye, Lifen Chen
Article Number: 174
Published online on: 18 March 2022

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Article Open Access

Reparative effects of chronic intermittent hypobaric hypoxia pre‑treatment on intervertebral disc degeneration in rats

Shu-Ren Liu, Dong Ren, Hao-Tan Wu, Shuang-Quan Yao, Zhao-Hui Song, Lin-Dan Geng, Peng-Cheng Wang
Article Number: 173
Published online on: 18 March 2022

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Article Open Access

Taurine attenuates ER stress‑associated apoptosis and catabolism in nucleus pulposus cells

Liuxie Yang, Zhenhuan Li, Yueping Ouyang
Article Number: 172
Published online on: 18 March 2022

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Review Open Access

Insights into the role of STAT3 in intrahepatic cholangiocarcinoma (Review)

Ranzhiqiang Yang, Yinghui Song, Kashif Shakoor, Weimin Yi, Chuang Peng, Sulai Liu
Article Number: 171
Published online on: 17 March 2022

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Article Open Access

Sigma‑1 receptor overexpression promotes proliferation and ameliorates cell apoptosis in β‑cells

Mengting Ke, Fengping Lin, Huawei Wang, Guangzhen He, Jieyuan Feng, Linyang Song, Yancheng Xu, Jie Liu
Article Number: 170
Published online on: 17 March 2022

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Review Open Access

Interactions of circRNAs with methylation: An important aspect of circRNA biogenesis and function (Review)

Chunlei Zhang, Han Cui, Chuang Huang, Feiyan Kong, Qi Yang, Pengcheng Miao, Zhigang Cao, Weijun Zhang, Dehui Chang
Article Number: 169
Published online on: 16 March 2022

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Article Open Access

E. coli JM83 damages the mucosal barrier in Ednrb knockout mice to promote the development of Hirschsprung‑associated enterocolitis via activation of TLR4/p‑p38/NF‑κB signaling

Zebing Zheng, Mingjuan Gao, Chengyan Tang, Lu Huang, Yuan Gong, Yuanmei Liu, Jian Wang
Article Number: 168
Published online on: 16 March 2022

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Article

Atorvastatin regulates vascular smooth muscle cell phenotypic transformation by epigenetically modulating contractile proteins and mediating Akt/FOXO4 axis

Xinping Du, Zhiyuan Sun, Zhongnan Cao, Xiuhong Zhou, Dong Wang, Kuan Wang, Xuebin Li, Guoxing Zuo
Article Number: 167
Published online on: 16 March 2022

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Review Open Access

The role of galectins‑1, 3, 7, 8 and 9 as potential diagnostic and therapeutic markers in ovarian cancer (Review)

Aleksandra Mielczarek‑Palacz, Zdzisława Kondera‑Anasz, Marta Smycz‑Kubańska, Aleksandra Englisz, Aleksandra Janusz, Patrycja Królewska‑Daszczyńska, Dominika Wendlocha
Article Number: 166
Published online on: 15 March 2022

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Article Open Access

Preserving mitochondrial function by inhibiting GRP75 ameliorates neuron injury under ischemic stroke

Bin Wen, Kai Xu, Rui Huang, Teng Jiang, Jian Wang, Jiehui Chen, Juan Chen, Benhong He
Article Number: 165
Published online on: 15 March 2022

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Article Open Access

KLF4 downregulates FGF21 to activate inflammatory injury and oxidative stress of LPS‑induced ATDC5 cells via SIRT1/NF‑κB/p53 signaling

Xi Chen, Jia Wen, Chaoqi Liu, Donggeng Guo
Article Number: 164
Published online on: 14 March 2022

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Correction Open Access

[Corrigendum] Type II cGMP‑dependent protein kinase inhibits the migration, invasion and proliferation of several types of human cancer cells

Min Wu, Yan Wu, Hai Qian, Yan Tao, Ji Pang, Ying Wang, Yongchang Chen
Article Number: 163
Published online on: 14 March 2022

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Article Open Access

Potential impact of GCK, MIR-196A-2 and MIR-423 gene abnormalities on the development and progression of type 2 diabetes mellitus in Asir and Tabuk regions of Saudi Arabia

Mohammad Muzaffar Mir, Rashid Mir, Mushabab Ayed Abdullah Alghamdi, Javed Iqbal Wani, Imadeldin Elfaki, Zia Ul Sabah, Muhanad Alhujaily, Mohammed Jeelani, Vijaya Marakala, Muffarah Hamid Alharthi, Abdullah M. Al‑Shahrani
Article Number: 162
Published online on: 14 March 2022

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Article Open Access

SESN1 attenuates the Ox‑LDL‑induced inflammation, apoptosis and endothelial‑mesenchymal transition of human umbilical vein endothelial cells by regulating AMPK/SIRT1/LOX1 signaling

Feng Gao, Yongcheng Zhao, Bin Zhang, Chunwei Xiao, Zhanfa Sun, Yuan Gao, Xueyong Dou
Article Number: 161
Published online on: 11 March 2022

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Article Open Access

P2X7 receptor knockdown suppresses osteoclast differentiation by inhibiting autophagy and Ca2+/calcineurin signaling

Yonggang Ma, Ran Di, Hongyan Zhao, Ruilong Song, Hui Zou, Zongping Liu
Article Number: 160
Published online on: 10 March 2022

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Article Open Access

Differential immunohistochemical expression of DEC1, CK‑1ε, and CD44 in oral atypical squamous epithelium and carcinoma in situ

Fuyuki Sato, Ujjal K. Bhawal, Shoko Osaki, Nao Sugiyama, Kosuke Oikawa, Yasuteru Muragaki
Article Number: 159
Published online on: 10 March 2022

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Article Open Access

Τelomerase inhibitors and activators in aging and cancer: A systematic review

Persefoni Fragkiadaki, Elisavet Renieri, Katerina Kalliantasi, Elisavet Kouvidi, Evita Apalaki, Elena Vakonaki, Charalampos Mamoulakis, Demetrios A. Spandidos, Aristidis Tsatsakis
Article Number: 158
Published online on: 08 March 2022

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Retraction Open Access

[Retracted] MicroRNA‑181 serves an oncogenic role in breast cancer via the inhibition of SPRY4

Yifu Tian, Xiaodan Fu, Qingling Li, Ying Wang, Dan Fan, Qin Zhou, Weilu Kuang, Liangfang Shen
Article Number: 157
Published online on: 04 March 2022

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Article Open Access

Co‑expressed microRNAs, target genes and pathways related to metabolism, inflammation and endocrine function in individuals at risk for type 2 diabetes

Elena Flowers, Kesava Asam, Isabel Elaine Allen, Alka M. Kanaya, Bradley E. Aouizerat
Article Number: 156
Published online on: 03 March 2022

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Article Open Access

CID16020046, a GPR55 antagonist, attenuates sepsis‑induced acute kidney injury

Rongxin Chen, Hailin Xu, Zebin Guo, Peng Zhang, Jianxia Chen, Zheng Chen
Article Number: 155
Published online on: 03 March 2022

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Article Open Access

The GABAB receptor agonist STX209 reverses the autism‑like behaviour in an animal model of autism induced by prenatal exposure to valproic acid

Shucai Jiang, Lifei Xiao, Yu Sun, Maotao He, Caibin Gao, Changliang Zhu, Haigang Chang, Jiangwei Ding, Wenchao Li, Yangyang Wang, Tao Sun, Feng Wang
Article Number: 154
Published online on: 02 March 2022

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Article Open Access

A novel non‑selective atypical PKC agonist could protect neuronal cell line from Aβ‑oligomer induced toxicity by suppressing Aβ generation

Dongmei Zou, Qian Li, Wenyang Pan, Peng Chen, Miao Sun, Xiaofeng Bao
Article Number: 153
Published online on: 02 March 2022

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Article

Exosome‑derived lncRNA‑Ankrd26 promotes dental pulp restoration by regulating miR‑150‑TLR4 signaling

Lin Li, Jianping Ge
Article Number: 152
Published online on: 02 March 2022

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Review

Potential clinical applications of alpha‑ketoglutaric acid in diseases (Review)

Xingqi Meng, Huiqing Liu, Lixuan Peng, Weiguo He, Suyun Li
Article Number: 151
Published online on: 02 March 2022

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Article Open Access

Lidocaine attenuates hypoxia/reoxygenation‑induced inflammation, apoptosis and ferroptosis in lung epithelial cells by regulating the p38 MAPK pathway

Xiaojun Ma, Weihua Yan, Na He
Article Number: 150
Published online on: 02 March 2022

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Article

USP22 promotes pro‑inflammatory responses in Pseudomonas aeruginosa‑induced keratitis by targeting TRAF6

Di Chen, Dawei Song, Yibin Ma, Weizhao Lu, Jianfeng Qiu, Yi Wang
Article Number: 149
Published online on: 02 March 2022

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Journal Cover
October-2026 Volume 34 Issue 4

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Journal Metrics

Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

Licoisoflavone A ameliorates adipose tissue dysfunction in diet‑induced obesity by promoting METTL3 expression

Shuangxi Tu, Xiaodan Wang, Zhenbo Wang, Haojun Tang, Kai Yin, Xiao Zhu
Article Number: 296
Published online on: 03 September 2026

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Review Open Access

Interaction of circular RNAs with splicing factors in cervical cancer: Modulation, interplay and theranostics (Review)

Amahle Nyalambisa, Afra Basera, Ntombikayise Xelwa, Olalekan Fadebi, Zodwa Dlamini, Rahaba Marima
Article Number: 295
Published online on: 03 September 2026

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Review Open Access

From oxidative stress to epigenetic regulation: Molecular mechanisms of preterm brain injury and neuroprotective strategies (Review)

Yuying Li, Ling Wei, Fang Sun, Huixia Wu, Xijun Sun, Yirong Gan, Xiaohua Kong
Article Number: 294
Published online on: 03 September 2026

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Review Open Access

Resurrection biology: Melatonin as a modulator of anastasis (Review)

Alexandros Georgiou, Russel J. Reiter, Vassilis Zoumpourlis, Demetrios A. Spandidos
Article Number: 293
Published online on: 02 September 2026

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Correction Open Access

[Corrigendum] CLEC4M overexpression inhibits progression and is associated with a favorable prognosis in hepatocellular carcinoma

Qianle Yu, Kai Gao
Article Number: 292
Published online on: 01 September 2026

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Review Open Access

Natural medicine‑empowered treatment of depression via restoring neurogenesis (Review)

Xiufen Zhong, Jingtao Gui
Article Number: 291
Published online on: 28 August 2026

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Article Open Access

POU2F1 promotes hypertensive cardiac fibrosis by regulating mitochondrial homeostasis through PINK1/Parkin‑dependent mitophagy

Yongbo Ma, Xiaozhe Chen, Zixian Liu, Yulong Ma, Chunlei Hou, Yunfeng Li, Mingtai Gui, Bo Lu, Deyu Fu, Mingzhu Wang
Article Number: 290
Published online on: 26 August 2026

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Correction Open Access

[Corrigendum] Human cytomegalovirus RL13 protein interacts with host NUDT14 protein affecting viral DNA replication

Guili Wang, Gaowei Ren, Xin Cui, Zhitao Lu, Yanping Ma, Ying Qi, Yujing Huang, Zhongyang Liu, Zhengrong Sun, Qiang Ruan
Article Number: 289
Published online on: 24 August 2026

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Review Open Access

Autophagy: Mechanisms and therapeutic perspectives in intestinal metaplasia (Review)

Laifeng Wu, Lingchen Liao, Ziwei Xia, Qiao Zeng, An Huang, Zhiyong Cao
Article Number: 288
Published online on: 21 August 2026

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Review Open Access

Unlocking the potential of microRNA as predictive biomarkers for efficacy and adverse events in immune checkpoint inhibitor therapy (Review)

Xi Wang, Baojun Duan, Jun Bai, Huitong Liu
Article Number: 287
Published online on: 20 August 2026

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Review Open Access

Mitochondrial dysfunction‑driven ferroptosis in cerebral ischemia‑reperfusion injury: Mechanisms and therapeutic strategies (Review)

Jianhui Li, Annan Liu, Wei Gao, Liping Xing, Peihan Duan, Honglin Li
Article Number: 286
Published online on: 20 August 2026

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Article Open Access

Inhibition of Dyrk1a attenuates type 1 diabetic cardiomyopathy via anti‑ferroptosis

Junjian Chen, Wanyi Zhang, Tao Hong, Junsheng Wang, Chuan Chen, Ying Zhang, Mi Hu, Ning You, Jietao Huang
Article Number: 285
Published online on: 20 August 2026

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Correction Open Access

[Corrigendum] Coenzyme Q10 alleviates sevoflurane‑induced neuroinflammation by regulating the levels of apolipoprotein E and phosphorylated tau protein in mouse hippocampal neurons 

Man Yang, Naqi Lian, Yang Yu, Yaoqi Wang, Keliang Xie, Yonghao Yu
Article Number: 284
Published online on: 20 August 2026

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Review Open Access

Deubiquitinating enzymes in kidney diseases: Molecular mechanisms, pathological roles and therapeutic opportunities (Review)

Qianqian Li, Yufang Ni, Zhaoyang Li, Jianchun Li, Li Wang
Article Number: 283
Published online on: 18 August 2026

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Review Open Access

Biological mechanisms of atropine in myopia control (Review)

Qin Zhu, Guanglong Zhou, Lingguo Wang, Xuejiao Li, Zhijuan Hua, Jie Yin, Jieying Zhang, Yuan Zhou, Xiaofan Zhang, Allison Wilde, Yingting Zhu, Liping Xue
Article Number: 282
Published online on: 18 August 2026

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Article Open Access

6'‑O‑Caffeoylarbutin attenuates experimental hyperuricemia by regulating renal and intestinal urate transport, intestinal barrier integrity, and gut microbiota

Xuezhi Yu, Yang Zhang, Konchun Sun, Rui Yang, Xingde Li, Xiuzhen Chen, Tiantian Li, Xiaolei Yang, Ming Li, Lu Liu, Fei Li, Baochun Shen
Article Number: 281
Published online on: 18 August 2026

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Retraction Open Access

[Retracted] Aberrant expression of miR‑130a‑3p in ankylosing spondylitis and its role in regulating T‑cell survival  

Fengju Li, Dingran Si, Xuejun Guo, Ningru Guo, Dandan Li, Liujing Zhang, Xianan Jian, Jiasheng Ma
Article Number: 280
Published online on: 17 August 2026

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Article Open Access

Uric acid enhances tumor stemness in breast cancer cells by upregulating GMPS

Zhiying Wang, Mingzhang Huang, Yuanqi Zhang, Siqi Huang, Wei Lei, Xiaorong Shui
Article Number: 279
Published online on: 13 August 2026

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Article Open Access

Construction and validation of a nomogram for the diagnosis of postmenopausal osteoporosis

Le-Yi Huang, Yao Chen, Lin-Ran Song, Zhuo-Lin Zhong, Kamran Ali, Hui-Min Li, Qing-Feng Hu, Hong-Hua Hu
Article Number: 278
Published online on: 13 August 2026

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Expression of Concern Open Access

[Expression of Concern] MicroRNA‑145‑5p suppresses fascin to inhibit the invasion and migration of cervical carcinoma cells

Shufang He, Guiyuan Yu, Ke Peng, Sisun Liu
Article Number: 277
Published online on: 12 August 2026

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Review

Research progress on drugs targeting mitochondria‑associated membranes for the treatment of atherosclerosis (Review)

Shaoying An, Wenhui Sun, Lizhou Shi, Hai Chen, Zhongcheng Mo
Article Number: 276
Published online on: 11 August 2026

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Retraction Open Access

[Retracted] A study of Sirt1 regulation and the effect of resveratrol on synoviocyte invasion and associated joint destruction in rheumatoid arthritis

Liang Hao, Yuying Wan, Juhua Xiao, Qiang Tang, Huan Deng, Lu Chen
Article Number: 275
Published online on: 10 August 2026

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Article Open Access

Histone deacetylase 3‑mediated histone deacetylation combined with activating transcription factor 3 promotes renal fibrosis by inhibiting Klotho

Zhiying Yang, Xueling Wang, Wenhong Li, Hao Chen, Gang Liu
Article Number: 274
Published online on: 06 August 2026

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Review Open Access

Mitochondrial quality control in acute liver injury and its therapeutic implications (Review)

Ziqiang Chen, Yunhe Wang, Yijing Li, Gang Cong, Yunhang Chu, Yunhui Bai, Yishuo Zhang, Liya Zhou
Article Number: 273
Published online on: 05 August 2026

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Article Open Access

STC1 promotes osteogenic differentiation and represses inflammation via inhibition of NF‑κB signaling in mesenchymal stromal cells

Chen Yang, Xin Li, Peng Wang, Yitong Chen, Erli Wu, Qian Chen, Jing Hu, Fu Zheng, Lamu Gongsang, Jiayu Li, Mengyuan Zhang, Jing Zhou, Bing Han, Amr A. Badreldin, Yuka Miyamoto, Jin Koo Kim, Insoon Chang, Jia Chang, Paul H. Krebsbach, Liyuan Huang, Xiaoping Xu, Xiaoyan Chen, Peng Deng, Qianming Chen, Lijie Fan
Article Number: 272
Published online on: 05 August 2026

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Review Open Access

Research progress on the protective effect and oxidative stress mechanism of rutin against liver injury (Review)

Teng Sun, Lei Ye
Article Number: 271
Published online on: 04 August 2026

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Review Open Access

Role of microbial metabolites in the pathogenesis of hypertensive disorders of pregnancy: From short‑chain fatty acids to tryptophan metabolites (Review)

Fengyun Gao, Lili Wang, Guiyun Teng, Liqiong Shang
Article Number: 270
Published online on: 03 August 2026

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Retraction Open Access

[Retracted] Tumor promoter role of miR‑647 in gastric cancer via repression of TP73

Xiangqian Zhang, Min Zhang, Guifeng Wang, Ye Tian, Xiaolong He
Article Number: 269
Published online on: 03 August 2026

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Review Open Access

Gut microbiota‑immune crosstalk in recurrent pregnancy loss: Mechanisms and therapeutic perspectives (Review)

Nanjian Luo, Han Hu, Xiaoting Zeng, Yi Huan Zhang, Qi Deng, En Ni Tang, Yu Hu
Article Number: 268
Published online on: 31 July 2026

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Review Open Access

Integrating gut‑brain axis insights into bundled nutrition care for critically ill patients: From mechanisms to implementation (Review)

Liqi Zhang, Shuxia Yang, Huiyan Wu, Hong Zhou
Article Number: 267
Published online on: 30 July 2026

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Review Open Access

Role of CMTM6 in disease pathogenesis and clinical translation potential (Review)

Rongtou Huang, Danning Mo, Huitian Huang, Minmin Zhang, Wenhong Yu, Buqing Cao
Article Number: 266
Published online on: 29 July 2026

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Correction Open Access

[Corrigendum] Identification of key differentially expressed genes associated with non‑small cell lung cancer by bioinformatics analyses

Yubo Xiao, Min Feng, Haiying Ran, Xiao Han, Xuegang Li
Article Number: 265
Published online on: 29 July 2026

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Review Open Access

Advances in miR‑200c regulation of apoptosis, pyroptosis and autophagy in disease (Review)

Xiaona Wang, Hua Du, Yingxu Shi
Article Number: 264
Published online on: 28 July 2026

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Review Open Access

Association between periodontitis and heart failure: Mechanisms and clinical implications (Review)

Xinyue Zhang, Xiaoli An
Article Number: 263
Published online on: 28 July 2026

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Article Open Access

Ginsenosides alleviate the progression of hepatic fibrosis by targeting the liver circadian clock gene CLOCK

Jiawen Yu, Chunmei Qian, Renye Que, Yi Zhou
Article Number: 262
Published online on: 28 July 2026

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Retraction Open Access

[Retracted] PPM1A as a key target of the application of Jiawei‑Maxing‑Shigan decoction for the attenuation of radiation‑induced epithelial‑mesenchymal transition in type II alveolar epithelial cells

Jinhua Lu, Shengyou Lin, Zechen Lin, Xianlei Lin, Yuezhong Shen, Jingyang Su
Article Number: 261
Published online on: 27 July 2026

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Article Open Access

UBE2A as a prognostic indicator across human cancers: Insights from multi‑omics and immune landscape analyses

Yun Wen, Pengfei Luo
Article Number: 260
Published online on: 23 July 2026

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Journal Cover
November-2026 Volume 34 Issue 5

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Journal Metrics

Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Artemisinin and its derivatives for metabolic syndrome: From multi‑target mechanisms to translational opportunities (Review)

Shuo Cao, Mo Yang, Siyu Qu, Jinsong Wu, Jiaheng Li, Ying Zhao
Article Number: 315
Published online on: 17 September 2026

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Demethylase FTO attenuates atherosclerotic plaque via upregulating ABCA1 and ABCG1 expression by targeting ATG5

Fengxia Guo, Mei He, Yaonan Li, Kangning Zhu, Bing Hu
Article Number: 314
Published online on: 16 September 2026

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Correction Open Access

[Corrigendum] Bcl11b regulates enamel matrix protein expression and dental epithelial cell differentiation during rat tooth development

Ziyue Li, Guoqing Chen, Yaling Yang, Weihua Guo, Weidong Tian
Article Number: 313
Published online on: 16 September 2026

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Review Open Access

Integrin αVβ3 as a context‑dependent regulator of bone homeostasis: Insights into osteoporosis pathogenesis and therapeutic targeting (Review)

Changshun Chen, Xingxi Hu, Sixing Wei, Yongcheng Deng, Qinggang Zhao, Ge Chen, Zhong Cheng, Jianhua Ji, Jinyi Gu
Article Number: 312
Published online on: 15 September 2026

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Therapeutic effects of exosome‑based hyperin delivery in a cyclophosphamide‑induced mouse model of diminished ovarian reserve

Yi Ying, Yue Wu, Ji Zhou, Yaming Wang, Hongtao Yin, Gang Lu, Ruolang Pan, Liangzhong Lv
Article Number: 311
Published online on: 15 September 2026

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Review Open Access

Arginine metabolism, polyamine homeostasis and ferroptosis in cancer: Molecular links and therapeutic opportunities (Review)

Xin Dong, Yongkun Hou, Jingjing Shao, Haixia Zhu, Jibin Liu
Article Number: 310
Published online on: 15 September 2026

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Review Open Access

Mitochondria‑associated endoplasmic reticulum membranes in degenerative musculoskeletal disorders: Mechanistic evidence and therapeutic perspectives (Review)

Shilong Meng, Xinlei Fu, Yawei Xu, Zhiliang Peng, Xu Zhang, Yanguang Cao, Binbin Tang, Xiaolin Shi, Kang Liu
Article Number: 309
Published online on: 15 September 2026

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Article Open Access

High‑fat diet exacerbates hepatic and adipose insulin signaling impairment and ovarian lesions in a rat model of letrozole‑induced polycystic ovary syndrome

Sunju So, Sujin Kwon, La Yoon Choi, Dae Yong Kim, Mi Hye Kim
Article Number: 308
Published online on: 15 September 2026

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Retraction Open Access

[Retracted] RNAi‑mediated A disintegrin and metalloproteinase 9 gene silencing inhibits the tumor growth of non‑small lung cancer in vitro and in vivo

Liang Chang, Fangchao Gong, Youbin Cui
Article Number: 307
Published online on: 14 September 2026

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Article Open Access

A four‑gene signature identifies TKI‑induced persister cells and uncovers a ZLN005‑induced pyroptotic vulnerability via the GSDME pathway in EGFR‑mutant lung cancer

Wenwen Chang, Jiaxin Yuan, Huilin Zhang, Ying Yu, Yan Ma, Mingyue Li, Wenjing Li, Hongxia Yan, Chongran Sun, Peng Zhang, Yang Tian, Feng Guo, Pan Li, Yang Sun
Article Number: 306
Published online on: 11 September 2026

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Review Open Access

Research advances in the microbiota‑gut‑brain axis and Parkinson's disease (Review)

Yangping Meng, Qian Liu, Hao Zou, Xingyu Zhu, Xinxin Mi, Sitong Li, Yutian Xia, Yucheng Ma, Qianyu Yang, Jiaxin Peng, Junrui Li, Xingliang Liu, Junli Chen
Article Number: 305
Published online on: 10 September 2026

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Article Open Access

Ameliorative effects of Paulownia tomentosa flower absolute on atopic dermatitis‑related responses in mast cells and keratinocytes and its chemical composition

Da Yeon Yoo, Kyung Jong Won, Do Yoon Kim, Yoon Yi Kim, Ji Hye Bae, Ji Seong Yun, Hwan Myung Lee
Article Number: 304
Published online on: 10 September 2026

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Retraction Open Access

[Retracted] PYGB siRNA inhibits the cell proliferation of human osteosarcoma cell lines

Shuwei Zhang, Yichi Zhou, Yuanyu Zha, Yang Yang, Linlong Wang, Jingfeng Li, Wei Jin
Article Number: 303
Published online on: 10 September 2026

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Article Open Access

KIF4A drives esophageal squamous cell carcinoma via Wnt/β‑catenin signaling and predicts poor prognosis

Jialong Chen, Tong Wang, Da Wang, Weiguo Liu, Chunlai Liu, Yang Yang, Xiangfu Sun, Lei Zhou
Article Number: 302
Published online on: 08 September 2026

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Review Open Access

Research progress of aptamers in the diagnosis and treatment of colorectal cancer (Review)

Yiwen Li, Penghui Yan, Ji Zhang, Binghui Wu, Min Li, Baoliang Bao
Article Number: 301
Published online on: 08 September 2026

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Review Open Access

Role of the circadian rhythm in squamous cell carcinoma: From molecular mechanism to therapy (Review)

Mary-Lyn Eichhorn, Anna M. Dmitrieva, Lydia Meder
Article Number: 300
Published online on: 08 September 2026

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Expression of Concern Open Access

[Expression of Concern] Ganoderma lucidum polysaccharide inhibits prostate cancer cell migration via the protein arginine methyltransferase 6 signaling pathway

Xiaohui Zhao, Dayu Zhou, Yunen Liu, Chun Li, Xiaoguang Zhao, Ying Li, Wei Li
Article Number: 299
Published online on: 07 September 2026

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Review Open Access

Multi‑omics approaches to decipher the molecular mechanisms of exercise‑mediated bone protection: From mechanistic insights to personalized exercise prescription (Review)

Bin Tian, Xuesong Chen, Xin Kang
Article Number: 298
Published online on: 03 September 2026

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Retraction Open Access

[Retracted] MicroRNA‑27a promotes tumorigenesis via targeting AKT in triple negative breast cancer

Jing Wu, Zhihui Sun, Huijie Sun, Yanhua Li
Article Number: 297
Published online on: 03 September 2026

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