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RCAS1 increases cell morphological changes in murine fibroblasts by reducing p38 phosphorylation

  • Authors:
    • Takuya Nishinakagawa
    • Mai Hazekawa
    • Masato Hosokawa
    • Daisuke Ishibashi
  • View Affiliations / Copyright

    Affiliations: Department of Immunological and Molecular Pharmacology, Faculty of Pharmaceutical Science, Fukuoka University, Fukuoka 814‑0180, Japan
    Copyright: © Nishinakagawa et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 62
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    Published online on: February 2, 2023
       https://doi.org/10.3892/mmr.2023.12949
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Abstract

Receptor‑binding cancer antigen expressed on SiSo cells (RCAS1) is a tumor‑associated antigen that is expressed in a number of human malignancies. RCAS1 acts as a ligand for a putative RCAS1 receptor that is present on various human cells including T and B lymphocytes and natural killer cells, in which it induces cell growth inhibition and apoptosis. It has been suggested that RCAS1 might serve an important role in tumor cell evasion from the host immune system. In fact, RCAS1 expression is related to malignant characteristics including tumor size, invasion depth, clinical stage and poor overall survival. The authors previously established doxycycline‑induced RCAS1 overexpression murine fibroblast L cells to analyze the biological functions of RCAS1 and reported that its expression inhibited cell cycle progression via the downregulation of cyclin D3, which subsequently induced apoptosis. Additionally, it was found that RCAS1 expression induced cell morphological changes prior to caspase‑mediated apoptosis. Thus, the present study examined signaling pathways associated with changes in cell morphology that were induced by RCAS1 expression. The data showed that increased RCAS1 expression caused a reduction in actin stress fibers and decreased cofilin phosphorylation. Recent studies have shown that p38 signaling regulates actin polymerization. The data the present study showed that increased RCAS1 expression significantly decreased p38 phosphorylation.
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1 

Fontana A, Frei K, Bodmer S, Hofer E, Schreier MH, Palladino MA Jr and Zinkernagel RM: Transforming growth factor-beta inhibits the generation of cytotoxic T cells in virus-infected mice. J Immunol. 143:3230–3234. 1989. View Article : Google Scholar : PubMed/NCBI

2 

Li MO, Wan YY, Sanjabi S, Robertson AK and Flavell RA: Transforming growth factor-beta regulation of immune responses. Annu Rev Immunol. 24:99–146. 2006. View Article : Google Scholar : PubMed/NCBI

3 

Kriegel MA, Li MO, Sanjabi S, Wan YY and Flavell RA: Transforming growth factor-beta: Recent advances on its role in immune tolerance. Curr Rheumatol Rep. 8:138–144. 2006. View Article : Google Scholar : PubMed/NCBI

4 

Pisa P, Halapi E, Pisa EK, Gerdin E, Hising C, Bucht A, Gerdin B and Kiessling R: Selective expression of interleukin 10, interferon gamma, and granulocyte-macrophage colony-stimulating factor in ovarian cancer biopsies. Proc Natl Acad Sci USA. 89:7708–7712. 1992. View Article : Google Scholar : PubMed/NCBI

5 

De Smedt T, Van Mechelen M, De Becker G, Urbain J, Leo O and Moser M: Effect of interleukin-10 on dendritic cell maturation and function. Eur J Immunol. 27:1229–1235. 1997. View Article : Google Scholar : PubMed/NCBI

6 

Reed JC: Apoptosis-targeted therapies for cancer. Cancer Cell. 3:17–22. 2003. View Article : Google Scholar : PubMed/NCBI

7 

Andreola G, Rivoltini L, Castelli C, Huber V, Perego P, Deho P, Squarcina P, Accomero P, Lozupone P, Lugini L, et al: Induction of lymphocyte apoptosis by tumor cell secretion of FasL-bearing microvesicles. J Exp Med. 195:1303–1316. 2002. View Article : Google Scholar : PubMed/NCBI

8 

Okada K, Komuta K, Hashimoto S, Matsuzaki S, Kanematsu T and Koji T: Frequency of apoptosis of tumor-infiltrating lymphocytes induced by fas counterattack in human colorectal carcinoma and its correlation with prognosis. Clin Cancer Res. 6:3560–3564. 2000.PubMed/NCBI

9 

Reimer T, Herrnring C, Koczan D, Richter D, Gerber B, Kabelitz D, Friese K and Thiesen HJ: FasL:Fas ratio-a prognostic factor in breast carcinomas. Cancer Res. 60:822–828. 2002.PubMed/NCBI

10 

Bennett MW, O'Connell J, O'Sullivan GC, Brady C, Roche D, Collins JK and Shanahan F: The Fas counterattack in vivo: Apoptotic depletion of tumor-infiltrating lymphocytes associated with Fas ligand expression by human esophageal carcinoma. J Immunol. 160:5669–5675. 1998. View Article : Google Scholar : PubMed/NCBI

11 

O'Connell J, Bennett MW, O'Sullivan GC, Collins JK and Shanahan F: The Fas counterattack: Cancer as a site of immune privilege. Immunol Today. 120:46–52. 1999. View Article : Google Scholar

12 

Rivoltini L, Carrabba M, Huber V, Castelli C, Novellino L, Dalerba P, Mortarini R, Arancia G, Anichini A, Fais S and Parmiani G: Immunity to cancer: Attack and escape in T lymphocyte-tumor cell interaction. Immunol Rev. 188:97–113. 2002. View Article : Google Scholar : PubMed/NCBI

13 

Huber V, Fais S, Iero M, Lugini L, Canese P, Squarcina P, Zaccheddu A, Colone M, Arancia G, Gentile M, et al: Human colorectal cancer cells induce T-cell death through release of proapoptotic microvesicles: Role in immune escape. Gastroenterology. 128:1796–1804. 2005. View Article : Google Scholar : PubMed/NCBI

14 

Giovarelli M, Musiani P, Garotta G, Ebner R, Di Carlo E, Kim Y, Cappello P, Rigamonti L, Bernabei P, Novelli F, et al: A ‘stealth effect’: Adenocarcinoma cells engineered to express TRAIL elude tumor-specific and allogeneic T cell reactions. J Immunol. 163:4886–4893. 1999. View Article : Google Scholar : PubMed/NCBI

15 

Koyama S, Koike N and Adachi S: Expression of TNF-related apoptosis-inducing ligand (TRAIL) and its receptors in gastric carcinoma and tumor-infiltrating lymphocytes: A possible mechanism of immune evasion of the tumor. J Cancer Res Clin Oncol. 128:73–79. 2002. View Article : Google Scholar : PubMed/NCBI

16 

Kassouf N and Thornhill MH: Oral cancer cell lines can use multiple ligands, including Fas-L, TRAIL and TNF-alpha, to induce apoptosis in Jurkat T cells: Possible mechanisms for immune escape by head and neck cancers. Oral Oncol. 44:672–682. 2008. View Article : Google Scholar : PubMed/NCBI

17 

Sonoda K, Nakashima M, Saito T, Amada S, Kamura T, Nakano H and Watanabe T: Establishment of a new human uterine cervical adenocarcinoma cell-line, siso, and its reactivity to anticancer reagents. Int J Oncol. 6:1099–1104. 1995.PubMed/NCBI

18 

Sonoda K, Nakashima M, Kaku T, Kamura T, Nakano H and Watanabe T: A novel tumor-associated antigen expressed in human uterine and ovarian carcinomas. Cancer. 77:1501–1509. 1996. View Article : Google Scholar : PubMed/NCBI

19 

Nakashima M, Sonoda K and Watanabe T: Inhibition of cell growth and induction of apoptotic cell death by the human tumor-associated antigen RCAS1. Nat Med. 5:938–942. 1999. View Article : Google Scholar : PubMed/NCBI

20 

Enjoji M, Nakamuta M, Noguchi K, Sugimoto R, Kotoh K, Nawata H, Nakashima M and Watanabe T: RCAS1 expression in immune-mediated liver diseases. J Clin Gastroenterol. 34:286–287. 2002. View Article : Google Scholar : PubMed/NCBI

21 

Enjoji M, Nakashima M, Yamaguchi K, Kotoh K and Nakamuta M: Significance of RCAS1 antigen in hepatocellular, cholangiocellular and pancreatic carcinomas. J Gastroenterol Hepatol. 20:1143–1148. 2005. View Article : Google Scholar : PubMed/NCBI

22 

Giaginis C, Giagini A and Theocharis S: Receptor-binding cancer antigen expressed on SiSo cells (RCAS1): A novel biomarker in the diagnosis and prognosis of human neoplasia. Histol Histopathol. 24:761–776. 2009.PubMed/NCBI

23 

Dutsch-Wicherek M: RCAS1, MT, and vimentin as potential markers of tumor microenvironment remodeling. Am J Reprod Immunol. 63:181–188. 2010. View Article : Google Scholar : PubMed/NCBI

24 

Sonoda K: Novel therapeutic strategies to target RCAS1, which induces apoptosis via ectodomain shedding. Histol Histopathol. 26:1475–1486. 2011.PubMed/NCBI

25 

Szubert S, Dziobek K and Wicherek L: High post-treatment serum soluble receptor-binding cancer antigen expressed on SiSo cells (sRCAS1) levels is associated with poor survival of patients with cervical cancer. J Obset Gynaecol Res. 46:499–506. 2020. View Article : Google Scholar : PubMed/NCBI

26 

Sonoda K, Miyamoto S, Nakashima M and Wake N: Receptor-binding cancer antigen expressed on SiSo cells induces apoptosis via ectodomain shedding. Exp Cell Res. 316:1795–1803. 2010. View Article : Google Scholar : PubMed/NCBI

27 

Nishinakagawa T, Fujii S, Nozaki T, Maeda T, Machida K, Enjoji M and Nakashima M: Analysis of cell cycle arrest and apoptosis induced by RCAS1. Int J Mol Med. 25:717–722. 2010.PubMed/NCBI

28 

Yamaguchi H and Condeelis J: Regulation of the actin cytoskeleton in cancer cell migration and invasion. Biochim Biophys Acta. 1773:642–652. 2007. View Article : Google Scholar : PubMed/NCBI

29 

Condeelis J, Singer R and Segall JE: The great escape: When cancer cells hijack the genes for chemotaxis and motility. Annu Rev Cell Dev Biol. 21:695–718. 2005. View Article : Google Scholar : PubMed/NCBI

30 

Sahai E: Mechanisms of cancer cell invasion. Curr Opin Genet Dev. 15:87–96. 2005. View Article : Google Scholar : PubMed/NCBI

31 

Yamaguchi H, Wyckoff J and Condeelis J: Cell migration in tumors. Curr Opin Cell Biol. 17:559–564. 2005. View Article : Google Scholar : PubMed/NCBI

32 

Kim B, van Golen CM and Feldman EL: Insulin-like growth factor I induces preferential degradation of insulin receptor substrate-2 through the phosphatidylinositol 3-kinase pathway in human neuroblastoma cells. Endocrinology. 146:5350–5357. 2005. View Article : Google Scholar : PubMed/NCBI

33 

Lavastre V, Chiasson S, Cavalli H and Girard D: Viscum album agglutinin-I induces apoptosis and degradation of cytoskeletal proteins via caspases in human leukaemia eosinophil AML14.3D10 cells: Differences with purified human eosinophils. Br J Haematol. 130:527–535. 2005. View Article : Google Scholar : PubMed/NCBI

34 

Lavastre V, Pelletier M, Saller R, Hostanska K and Girard D: Mechanisms involved in spontaneous and Viscum album agglutinin-I-induced human neutrophil apoptosis: Viscum album agglutinin-I accelerates the loss of antiapoptotic Mcl-1 expression and the degradation of cytoskeletal paxillin and vimentin proteins via caspases. J Immunol. 168:1419–1427. 2002. View Article : Google Scholar : PubMed/NCBI

35 

Levkau B, Herren B, Koyama H, Ross R and Raines EW: Caspase-mediated cleavage of focal adhesion kinase pp125FAK and disassembly of focal adhesions in human endothelial cell apoptosis. J Exp Med. 187:579–586. 1998. View Article : Google Scholar : PubMed/NCBI

36 

Frisch SM and Francis H: Disruption of epithelial cell-matrix interactions induces apoptosis. J Cell Biol. 124:619–626. 1994. View Article : Google Scholar : PubMed/NCBI

37 

Frisch SM, Vuori K, Ruoslahti E and Chan-Hui PY: Control of adhesion-dependent cell survival by focal adhesion kinase. J Cell Biol. 134:793–799. 1996. View Article : Google Scholar : PubMed/NCBI

38 

Wu WB, Peng HC and Huang TF: Disintegrin causes proteolysis of beta-catenin and apoptosis of endothelial cells. Involvement of cell-cell and cell-ECM interactions in regulating cell viability. Exp Cell Res. 286:115–127. 2003. View Article : Google Scholar : PubMed/NCBI

39 

Zhao JH, Reiske H and Guan JL: Regulation of the cell cycle by focal adhesion kinase. J Cell Biol. 143:1997–2008. 1998. View Article : Google Scholar : PubMed/NCBI

40 

Milligan RA, Whittaker D and Safer D: Molecular structure of F-actin and location of surface binding sites. Nature. 348:217–221. 1990. View Article : Google Scholar : PubMed/NCBI

41 

Dos Remedios CG, Chhabra D, Kekic M, Dedova IV, Tsubakihara M, Berry DA and Nosworthy NJ: Actin binding proteins: Regulation of cytoskeletal microfilaments. Physiol Rev. 83:433–473. 2003. View Article : Google Scholar : PubMed/NCBI

42 

Moon A and Drubin DG: The ADF/cofilin proteins: Stimulus-responsive modulators of actin dynamics. Mol Biol Cell. 6:1423–1431. 1995. View Article : Google Scholar : PubMed/NCBI

43 

Qi M and Elion EA: MAP kinase pathways. J Cell Sci. 118:3569–3572. 2005. View Article : Google Scholar : PubMed/NCBI

44 

Johnson GL and Lapadat R: Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases. Science. 298:1911–1912. 2002. View Article : Google Scholar : PubMed/NCBI

45 

Kobayashi M, Nishita M, Mishima T, Ohashi K and Mizuno K: MAPKAPK-2-mediated LIM-kinase activation is critical for VEGF-induced actin remodeling and cell migration. EMBO J. 25:713–726. 2006. View Article : Google Scholar : PubMed/NCBI

46 

Bian H, Li F, Wang W, Zhao Q, Gao S, Ma J, Li X, Ren W, Qin C and Qi J: MAPK/p38 regulation of cytoskeleton rearrangement accelerates induction of macrophage activation by TLR4, but not TLR3. Int J Mol Med. 40:1495–1503. 2017. View Article : Google Scholar : PubMed/NCBI

47 

Koul HK, Pal M and Koul S: Role of p38 MAP kinase signal transduction in solid tumors. Genes Cancer. 4:342–359. 2013. View Article : Google Scholar : PubMed/NCBI

48 

Pereira L, Igea A, Canovas B, Dolado I and Nebreda AR: Inhibition of p38 MAPK sensitizes tumour cells to cisplatin-induced apoptosis mediated by reactive oxygen species and JNK. EMBO Mol Med. 5:1759–1774. 2013. View Article : Google Scholar : PubMed/NCBI

49 

Bakour N, Moriarty F, Moore G, Robson T and Annett SL: Prognostic significance of glucocorticoid receptor expression in cancer: A systematic review and meta-analysis. Cancers (Basel). 13:16492021. View Article : Google Scholar : PubMed/NCBI

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Copy and paste a formatted citation
Spandidos Publications style
Nishinakagawa T, Hazekawa M, Hosokawa M and Ishibashi D: RCAS1 increases cell morphological changes in murine fibroblasts by reducing p38 phosphorylation. Mol Med Rep 27: 62, 2023.
APA
Nishinakagawa, T., Hazekawa, M., Hosokawa, M., & Ishibashi, D. (2023). RCAS1 increases cell morphological changes in murine fibroblasts by reducing p38 phosphorylation. Molecular Medicine Reports, 27, 62. https://doi.org/10.3892/mmr.2023.12949
MLA
Nishinakagawa, T., Hazekawa, M., Hosokawa, M., Ishibashi, D."RCAS1 increases cell morphological changes in murine fibroblasts by reducing p38 phosphorylation". Molecular Medicine Reports 27.3 (2023): 62.
Chicago
Nishinakagawa, T., Hazekawa, M., Hosokawa, M., Ishibashi, D."RCAS1 increases cell morphological changes in murine fibroblasts by reducing p38 phosphorylation". Molecular Medicine Reports 27, no. 3 (2023): 62. https://doi.org/10.3892/mmr.2023.12949
Copy and paste a formatted citation
x
Spandidos Publications style
Nishinakagawa T, Hazekawa M, Hosokawa M and Ishibashi D: RCAS1 increases cell morphological changes in murine fibroblasts by reducing p38 phosphorylation. Mol Med Rep 27: 62, 2023.
APA
Nishinakagawa, T., Hazekawa, M., Hosokawa, M., & Ishibashi, D. (2023). RCAS1 increases cell morphological changes in murine fibroblasts by reducing p38 phosphorylation. Molecular Medicine Reports, 27, 62. https://doi.org/10.3892/mmr.2023.12949
MLA
Nishinakagawa, T., Hazekawa, M., Hosokawa, M., Ishibashi, D."RCAS1 increases cell morphological changes in murine fibroblasts by reducing p38 phosphorylation". Molecular Medicine Reports 27.3 (2023): 62.
Chicago
Nishinakagawa, T., Hazekawa, M., Hosokawa, M., Ishibashi, D."RCAS1 increases cell morphological changes in murine fibroblasts by reducing p38 phosphorylation". Molecular Medicine Reports 27, no. 3 (2023): 62. https://doi.org/10.3892/mmr.2023.12949
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