The role of mesenchymal stem cell‑derived exosomes in asthma (Review)
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- Published online on: April 11, 2025 https://doi.org/10.3892/mmr.2025.13531
- Article Number: 166
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Copyright: © Lv et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
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Abstract
Asthma is a chronic respiratory disorder characterized by persistent inflammation, airway hyper‑responsiveness and remodeling, leading to notable morbidity and decreased quality of life for patients. Mesenchymal stem cells (MSCs) have potential in regenerative medicine due to their potent immunomodulatory properties and anti‑inflammatory effects. The therapeutic benefits of MSCs are largely mediated by secreted exosomes that facilitate intercellular communication by transferring bioactive molecules, including proteins, lipids and microRNAs. The present review explores the therapeutic potential of MSC‑derived exosomes in asthma, highlighting their ability to modulate key pathological mechanisms underlying the disease.
