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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
June-2025 Volume 31 Issue 6

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Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Crosstalk between white adipose tissue and skin: Unraveling its role in psoriasis pathogenesis (Review)

Qiuhe Song, Pengfei Xu, Qipeng Xiao, Chaowen Zhang, Yousheng Mao
Article Number: 169
Published online on: 11 April 2025

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Effects of chloroquine and hydroxychloroquine on bone health (Review)

Sok Kuan Wong
Article Number: 168
Published online on: 11 April 2025

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Preliminary exploration of endoplasmic reticulum stress transmission in astrocytes and neurons, and its mediators

Yating Ling, Muhammad Abid Hayat, Xiaorui Lv, Dongdong Niu, Yu Zeng, Yun Qiu, Bo Chen, Jiabo Hu
Article Number: 167
Published online on: 11 April 2025

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The role of mesenchymal stem cell‑derived exosomes in asthma (Review)

Kaiying Lv, Jiawei Gao, Liuxin Yang, Xingxing Yuan
Article Number: 166
Published online on: 11 April 2025

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Identification of the clinical value and biological effects of TTN mutation in liver cancer

Zhixue Zhang, Yating Sun, Zhirui Zeng, Dahuan Li, Wenpeng Cao, Shan Lei, Tengxiang Chen
Article Number: 165
Published online on: 11 April 2025

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Application of non‑coding RNAs in tumors (Review)

Zhihan Zhang, Chunyan Mao, Yi Wu, Yin Wang, Hui Cong
Article Number: 164
Published online on: 11 April 2025

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Landscape of lncRNAs expressed in Mexican patients with triple‑negative breast cancer 

Rosario Castro‑Oropeza, Cindy Velazquez‑Velazquez, Karla Vazquez‑Santillan, Alejandra Mantilla‑Morales, Martha Eugenia Ruiz Tachiquin, Javier Torres, Nora Rios‑Sarabia, Hector Mayani, Patricia Piña‑Sanchez
Article Number: 163
Published online on: 10 April 2025

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Correction Open Access

[Corrigendum] Ampelopsis japonica ethanol extract suppresses migration and invasion in human MDA‑MB‑231 breast cancer cells

Kyoung Jin Nho, Jin Mi Chun, Dong-Seon Kim, Ho Kyoung Kim
Article Number: 162
Published online on: 10 April 2025

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Perimenopausal depression: Targeting inflammation and oxidative stress (Review)

Yang Yu, Tianyang Yu, Kaili Liu, Yushuai Li, Yifeng Luan, Tianyi Yang, Wenzhong Li, Huifang Cong, Xiuhong Wu
Article Number: 161
Published online on: 10 April 2025

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Exploring the mechanism of fibronectin extra domain B in the tumor microenvironment and implications for targeted immunotherapy and diagnostics (Review)

Yuan Zhou, Tao Chen, Yawen Pan, Jing Liu
Article Number: 160
Published online on: 10 April 2025

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MG132 induces cell type‑specific anticancer effects in uterine leiomyosarcoma cell lines

Hosouk Joung, Suho Seo, Hyunju Liu
Article Number: 159
Published online on: 10 April 2025

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Role and mechanism of mitochondrial dysfunction‑related gene biomarkers in the progression of type 2 diabetes mellitus

Mengxue Liu, Hong Qiao
Article Number: 158
Published online on: 10 April 2025

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Resveratrol inhibits lipopolysaccharide‑induced MUC5AC expression and airway inflammation via MAPK and Nrf2 pathways in human bronchial epithelial cells and an acute inflammatory mouse model

Qiaojuan Chen, Liutian Xie, Jianming Wang, Xiaoshan Su, Xiangjia Ye, Xiaoping Lin
Article Number: 157
Published online on: 10 April 2025

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Brevilin A inhibits IL‑17A‑induced inflammation in psoriasis by modulating HSP 70 

Chia-Ling Li, Kuei-Ying Yeh, Wen-Nan Huang, Chung-Yang Yen, Kai-Chun Wang, En-Chih Liao, Ting-Yu Chou, Hung-Sen Huang, Sheng-Jie Yu
Article Number: 156
Published online on: 08 April 2025

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Myeloid SHP2 attenuates myocardial ischemia‑reperfusion injury via regulation of BRD4/SYK/STING/NOX4/NLRP3 signaling

Yazhong Liu, Hongshan Yin, Tao Wang, Tao Chen, Chengda Guo, Fue Zhang, Zhian Jiang
Article Number: 155
Published online on: 08 April 2025

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Retraction Open Access

[Retracted] Grooved hydroxyapatite scaffold modulates mitochondria homeostasis and thus promotes osteogenesis in bone mesenchymal stromal cells

Chenglong Li, Lu Yang, Xiaohua Ren, Mu Lin, Daonan Shen, You Li, Xiangyu Zhang, Chunhui Liu, Yandong Mu
Article Number: 154
Published online on: 07 April 2025

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Pristimerin ameliorates colitis‑induced intestinal mucosal injury by inhibiting intestinal epithelial necroptosis

Siqi Liu, Yuanyuan Wang, Keyi Lu, Yifan Shi, Zhibin Wang, Erping Xu
Article Number: 153
Published online on: 04 April 2025

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Osteochondral tissue engineering‑based subchondral bone plate repair (Review)

Xiaoyang Zhang, Weibo Jiang, Quezhu Danzeng, Yi Shen, Mengying Cui
Article Number: 152
Published online on: 04 April 2025

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Natural bioactive gallic acid shows potential anticancer effects by inhibiting the proliferation and invasiveness behavior in human embryonic carcinoma cells

Dong Young Kang, Se Won Bae, Kyoung-Jin Jang
Article Number: 151
Published online on: 04 April 2025

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Advances in research on flavonoids in tumor immunotherapy (Review)

Chaoguang Yan, Guangchun Wang
Article Number: 150
Published online on: 04 April 2025

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Article

Triptolide inhibits migration and viability, and promotes apoptosis by targeting the PI3K/Akt signaling pathway via upregulation of miR‑125a‑5p in SW1353 human chondrosarcoma cells

Chaoyi Liang, Zhang Zhuoer, Liu Yuan, Zhang Bing
Article Number: 149
Published online on: 04 April 2025

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Retraction Open Access

[Retracted] Effect of Etiasa on the expression of matrix metalloproteinase‑2 and tumor necrosis factor‑α in a rat model of ulcerative colitis

Jing-Wei Mao, Hai-Ying Tang, Xiao-Yan Tan, Ying-De Wang
Article Number: 148
Published online on: 02 April 2025

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Multifunctional cosmetic potential of extracellular vesicle‑like nanoparticles derived from the stem of Cannabis sativa in treating pigmentation disorders

Hyeon Jin Lee, Yun Hye Kim, Seo Jun Lee, Su Hyun Park, Jae-Min Yuk, Jae Cheol Jeong, Young Bae Ryu, Woo Sik Kim
Article Number: 147
Published online on: 01 April 2025

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α‑ketoglutarate protects against septic cardiomyopathy by improving mitochondrial mitophagy and fission

Wei Wu, Qiong Ma, Bo-Tao Li, Shuang Shi, Gong-Chang Guan, Jun-Kui Wang, Bao-Yao Xue, Zhong-Wei Liu
Article Number: 146
Published online on: 01 April 2025

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RNA‑seq analysis of predictive markers associated with glutamine metabolism in thyroid cancer

Yi You, Yuheng Zhou, Zilu Chen, Longcheng Deng, Yaping Shen, Qin Wang, Wei Long, Yan Xiong, Foxing Tan, Haolin Du, Yan Yang, Jiang Zhong, Yunqian Ge, Youchen Li, Yan Huang
Article Number: 145
Published online on: 01 April 2025

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Role of DNA methylation and non‑coding RNAs expression in pathogenesis, detection, prognosis, and therapy‑resistant ovarian carcinoma (Review)

Victor M. Del Castillo Falconi, Jenny A. Godinez Rodriguez, Verónica Fragoso‑Ontiveros, Laura Contreras‑Espinosa, Abraham Pedroza‑Torres, José Díaz‑Chávez, Luis A. Herrera
Article Number: 144
Published online on: 01 April 2025

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Retraction Open Access

[Retracted] Everolimus inhibits breast cancer cell growth through PI3K/AKT/mTOR signaling pathway

Liyan Du, Xiaomei Li, Linhong Zhen, Weiling Chen, Lingguang Mu, Yang Zhang, Ailin Song
Article Number: 143
Published online on: 31 March 2025

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Role of m5C methylation in digestive system tumors (Review)

Li Zhang, Jianbo Yuan, Shun Yao, Guorong Wen, Jiaxing An, Hai Jin, Biguang Tuo
Article Number: 142
Published online on: 28 March 2025

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Current research on mitochondria‑associated membranes in cardiovascular diseases (Review)

Jiaheng Zhang, Jing Tao, Zijuan Zhou, Wanjuan Pei, Yili Xiao, Yanghongxu Guo, Jian Gao, Chenyv Jiang, Ling Dai, Guomin Zhang, Chao Tan
Article Number: 141
Published online on: 28 March 2025

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Combination of tumor organoids with advanced technologies: A powerful platform for tumor evolution and treatment response (Review)

Ying Wu, Fan Zhang, Furong Du, Juan Huang, Shuqing Wei
Article Number: 140
Published online on: 27 March 2025

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Retraction Open Access

[Retracted] Knockdown of TRIM9 attenuates irinotecan‑induced intestinal mucositis in IEC‑6 cells by regulating DUSP6 expression via the P38 pathway

Wenjun Zhao, Qingming Wang
Article Number: 139
Published online on: 27 March 2025

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Journal Cover
March-2026 Volume 33 Issue 3

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article

CTRP4 ameliorates dexamethasone‑induced insulin resistance through the IRS‑1/PI3K/AKT pathway in 3T3‑L1 adipocytes

Maireyanmu Rouzi, Xi Sun, Luguang Sheng, Bilin Xu, Tao Lei, Jun Lu, Jie Gao
Article Number: 101
Published online on: 27 January 2026

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PTUPB, a soluble epoxide hydrolase/cyclooxygenase‑2 dual inhibitor, reduces endothelial‑to‑mesenchymal transition and improves doxorubicin‑induced vascular and cardiac toxicity

Hevna Dhulkifle, Lubna Therachiyil, Maram H. Hasan, Shahd M. Younis, Nizar A. Al‑Shar'i, Huseyin C. Yalcin, Zaid H. Maayah
Article Number: 100
Published online on: 27 January 2026

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Retraction Open Access

[Retracted] miR‑367 enhances the proliferation and invasion of cutaneous malignant melanoma by regulating phosphatase and tensin homolog expression

Jianwen Long, Jing Luo, Xuwen Yin
Article Number: 99
Published online on: 26 January 2026

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Review Open Access

Advances in the mechanisms of the NLRP3 inflammasome in sepsis‑induced cardiomyopathy and targeted therapeutic studies 
(Review)

Yifei Chen, Zhaohui Zhang, Gaosheng Zhou
Article Number: 98
Published online on: 22 January 2026

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HMGN2 induces pyroptosis in tumour cells by modulating the STT3B/PD‑L1/caspase‑1/GSDMD axis

Wenwen Han, Hongli Chen, Bomiao Cui, Jiao Chen, Ping Zhang, Yun Feng
Article Number: 97
Published online on: 22 January 2026

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Naringin ameliorates intestinal injury in ulcerative colitis model mice by modulating the JAK2/STAT3 signaling pathway

Miaomiao Wu, Yating An, Yongmin Li, Wei He, Ying Wang, Yaqi Wang, Caixia Wu
Article Number: 96
Published online on: 22 January 2026

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Review

PDX1 in human cancers: Molecular mechanisms, dual roles and clinical implications (Review)

Chen Zhou, Yifei Wang, Jie Zhao, Yantao Yang, Yuhang Yuan, Xiaochen Hou, Yu Tang, Lianhua Ye
Article Number: 95
Published online on: 22 January 2026

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Retraction Open Access

[Retracted] Autophagy flux inhibition mediated by celastrol sensitized lung cancer cells to TRAIL‑induced apoptosis via regulation of mitochondrial transmembrane potential and reactive oxygen species

Uddin Md Nazim, Honghua Yin, Sang-Youel Park
Article Number: 94
Published online on: 19 January 2026

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Converting ‘cold’ to ‘hot’ hepatocellular carcinoma for improved immunotherapy (Review)

Ching-Hua Hsieh, Pei-Chin Chuang
Article Number: 93
Published online on: 15 January 2026

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Article Open Access

Pathological mechanism of ferroptosis in a rat model of α‑naphthyl isothiocyanate‑induced chronic cholestasis

Zhen Guo, Jiaxuan Wang, Yiwen Wang, Xinzhu Liu, Yubing Xia, Ping Liu, Li Qi, Jia Liu, Xiaoning Wang
Article Number: 92
Published online on: 14 January 2026

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Correction Open Access

[Corrigendum] Role of hypoxia‑inducible factor‑1α and CD146 in epidermal growth factor receptor‑mediated angiogenesis in salivary gland adenoid cystic carcinom

Wei-Ming Wang, Zhi-Li Zhao, Wen-Feng Zhang, Yi-Fang Zhao, Lu Zhang, Zhi-Jun Sun
Article Number: 91
Published online on: 13 January 2026

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Review Open Access

Klebsiella pneumoniae and pyogenic liver abscess: Emerging clinical threats, virulence mechanisms and therapeutic strategies (Review)

Gulam Mustafa Hasan, Taj Mohammad, Sobia Zaidi, Anas Shamsi, Sukhwinder Singh Sohal, Md. Imtaiyaz Hassan
Article Number: 90
Published online on: 13 January 2026

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Collagen III regulates the termination of liver regeneration by suppressing hepatocyte proliferation and promoting functional recovery

Haiyang Peng, Zhiyong Chen, Qiwei Zhang, Yuezhou Zhang, Peng Yang, Jianping Gong, Andong Zhao
Article Number: 89
Published online on: 13 January 2026

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Review Open Access

Application of extracellular vesicles in the diagnosis and treatment of chronic obstructive pulmonary disease (Review)

Yixin Zhang, Tong Ren, Jianbo Xue, Yan Yu, Xianqiang Zhou, Xiaoyi Hu, Wenyi Yu, Zhancheng Gao, Cuiling Feng
Article Number: 88
Published online on: 13 January 2026

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Cigarette smoke combined with Klebsiella pneumoniae induce damage to the air‑blood barrier in chronic obstructive pulmonary disease rats via the MAPK/NF‑κB/IκBα pathway

Yange Tian, Kexin Xu, Ruilong Lu, Kangchen Li, Xuejie Shao, Yixi Liao, Yakun Zhao, Zhiguang Qiu, Haoran Dong, Xuefang Liu
Article Number: 87
Published online on: 12 January 2026

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Retraction Open Access

[Retracted] 8‑bromo‑7‑methoxychrysin induces apoptosis by regulating Akt/FOXO3a pathway in cisplatin‑sensitive and resistant ovarian cancer cells

Qing Ding, Yi Chen, Qing Zhang, Yanling Guo, Zhi Huang, Liqing Dai, Sudan Cao
Article Number: 86
Published online on: 12 January 2026

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Article Open Access

Anxiety‑induced overactive bladder: The role of oxidative stress and NF‑κB signaling pathway with Hsp90 as a potential biomarker

Zhipeng Zhou, Lina Xu, Han Wu, Huaishan Hong
Article Number: 85
Published online on: 12 January 2026

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Echinacoside alleviates asthenozoospermia by upregulating Sox5‑mediated transcriptional activation of the CatSper gene

Zi-Run Jin, Yong-Wei Huo, Bo-Heng Liu, Hong Tian, Shuo Yuan, Yue Tian, Ke Xi, Jie Cai, Hui Jiang, Yong Jiang, Guo-Gang Xing
Article Number: 84
Published online on: 12 January 2026

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Article Open Access

Artemisiae Scopariae Herba (Yinchen) suppresses ferroptosis in mice with osteoporosis via the Nrf2/Slc7a11/Gpx4 pathway

Pei Li, Xinyu Wan, Wenjie Li, Ding Cheng, Ying Yang, Yuhan Wang, Ruyuan Zhu, Yanjing Chen, Haixia Liu, Zhiguo Zhang
Article Number: 83
Published online on: 12 January 2026

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Review Open Access

Prolyl hydroxylase domain proteins: Localization, regulation, function and their role in erythropoiesis (Review)

Yan Hou, Zhao-Hua Zhang, Wen-Qian Li, Guo-Xiong Han, Kuo Shen, You-Bang Xie
Article Number: 82
Published online on: 12 January 2026

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Therapeutic potential of saponins for allergic rhinitis: Molecular mechanisms and clinical perspectives (Review)

Bing-Yu Liang, Zi-Yue Fu, Fen-Fen Li, Ping-Ting Zhou, Zi-Hui Xie, Ke Han, Yan-Xun Han, Shan-Wen Chen, Yi Zhao, Hai-Feng Pan, Ye-Hai Liu, Yu-Chen Liu
Article Number: 81
Published online on: 07 January 2026

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Interleukin‑6 and ischemic stroke: From mechanisms to clinical prospects (Review)

Xinyue Wang, Xiaohang Zhang, Jianing Lin, Ping Lin
Article Number: 80
Published online on: 05 January 2026

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Article Open Access

Preliminary exploration of the putative function of SF3A2 in clear cell renal cell carcinoma

Ru Chen, Jie Xu
Article Number: 79
Published online on: 05 January 2026

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Retraction Open Access

[Retracted] TIPE‑2 suppresses growth and aggressiveness of hepatocellular carcinoma cells through downregulation of the phosphoinositide 3‑kinase/AKT signaling pathway

Lin Wang, Chen Chen, Shuzhi Feng, Jianli Tian
Article Number: 78
Published online on: 05 January 2026

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Journal Cover
April-2026 Volume 33 Issue 4

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Circular RNAs in intervertebral disc degeneration: Current insights into mechanisms and therapeutic potentials (Review)

Luyan Wang, Ke Yang, Houjun Zhu, Dachuan Wang, Feng Wang, Xianfa Du
Article Number: 111
Published online on: 05 February 2026

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T‑cadherin and its impact on human diseases (Review)

Yan Song, Xinyi Wang, Yunfei Bian
Article Number: 110
Published online on: 05 February 2026

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Review

CD20 monoclonal antibody‑rituximab for the treatment of diffuse alveolar hemorrhage in children (Review)

Xiaobo Zhang, Xiao Wu, Yan Li, Guangmin Nong
Article Number: 109
Published online on: 05 February 2026

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N6‑methyladenosine reader insulin‑like growth factor 2 mRNA‑binding protein 2 promotes abnormal proliferation of colonic epithelial cells in type 2 diabetes mellitus by regulating midkine

Jieyao Li, Qingsheng Xie, Jihao Xu
Article Number: 108
Published online on: 04 February 2026

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Expression of Concern Open Access

[Expression of Concern] Curcumin suppresses breast tumor angiogenesis by abrogating osteopontin‑induced VEGF expression

Goutam Chakraborty, Shalini Jain, Smita Kale, Remya Raja, Santosh Kumar, Rosalin Mishra, Gopal C. Kundu
Article Number: 107
Published online on: 04 February 2026

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Review Open Access

Research status and molecular mechanisms of disulfidptosis in cardiovascular diseases (Review)

Xiao Jin, Zelin Cheng, Xinyue Ding, Zongjun Liu
Article Number: 106
Published online on: 03 February 2026

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Role and mechanism of tetrahedral DNA nanostructures in the repair of urethral injury in rats

Caifen Guo, Jian Li
Article Number: 105
Published online on: 02 February 2026

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Retraction Open Access

[Retracted] MicroRNA‑4500 suppresses tumor progression in non‑small cell lung cancer by regulating STAT3

Zhi-Ying Li, Zi-Zhou Zhang, Hui Bi, Qiu-Di Zhang, Su-Juan Zhang, Lin Zhou, Xiao-Qin Zhu, Jun Zhou
Article Number: 104
Published online on: 02 February 2026

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Article Open Access

Integrative bioinformatics and experimental analysis reveals FRA1 as a key mediator of tubulointerstitial inflammation in lupus nephritis

Wenpeng Ni, Jialin He, Zhouyu Zeng, Jialong Ke, Runpei Lin, Jianming Peng, Kunyi Deng, Lijuan Wen, Yanhui Chen, Chilun Zhang, Yanfen Li, Guanghong Gu
Article Number: 103
Published online on: 28 January 2026

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Correction Open Access

[Corrigendum] Resveratrol improves neurological outcome and neuroinflammation following spinal cord injury through enhancing autophagy involving the AMPK/mTOR pathway

Hong-Yu Meng, De-Cheng Shao, Han Li, Xiao-Dan Huang, Guang Yang, Bing Xu, Hai-Yun Niu
Article Number: 102
Published online on: 28 January 2026

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