|
1
|
Tan Y, Zhang M, Kong Y, Zhang F, Wang Y,
Huang Y, Song W, Li Z, Hou L, Liang L, et al: Fibroblasts and
endothelial cells interplay drives hypertrophic scar formation:
Insights from in vitro and in vivo models. Bioeng Transl Med.
9:e106302023. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Sun X, Nkennor B, Mastikhina O, Soon K and
Nunes SS: Endothelium-mediated contributions to fibrosis. Semin
Cell Dev Biol. 101:78–86. 2020. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Ramasamy SK, Kusumbe AP and Adams RH:
Regulation of tissue morphogenesis by endothelial cell-derived
signals. Trends Cell Biol. 25:148–157. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Sgonc R and Gruber J: Age-related aspects
of cutaneous wound healing: A mini-review. Gerontology. 59:159–164.
2013. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Brauer E, Lange T, Keller D, Görlitz S,
Cho S, Keye J, Gossen M, Petersen A and Kornak U: Dissecting the
influence of cellular senescence on cell mechanics and
extracellular matrix formation in vitro. Aging Cell. 22:e137442023.
View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Dańczak-Pazdrowska A, Gornowicz-Porowska
J, Polańska A, Krajka-Kuźniak V, Stawny M, Gostyńska A, Rubiś B,
Nourredine S, Ashiqueali S, Schneider A, et al: Cellular senescence
in skin-related research: Targeted signaling pathways and naturally
occurring therapeutic agents. Aging Cell. 22:e138452023. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Yu GT, Monie DD, Khosla S, Tchkonia T,
Kirkland JL and Wyles SP: Mapping cellular senescence networks in
human diabetic foot ulcers. Geroscience. 46:1071–1082. 2024.
View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Pilkington SM, Bulfone-Paus S, Griffiths
CEM and Watson REB: Inflammaging and the Skin. J Invest Dermatol.
141((4S)): 1087–1095. 2021. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Ding X, Kakanj P, Leptin M and Eming SA:
Regulation of the Wound Healing Response during Aging. J Invest
Dermatol. 141((4S)): 1063–1070. 2021. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Zhou S, Li Z, Li X, Ye Y, Wang M, Jiang J,
Tao L, Wang Y, Tung CT, Chung Y, et al: Crosstalk between
endothelial cells and dermal papilla entails hair regeneration and
angiogenesis during aging. J Adv Res. 70:339–353. 2025. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Reed MJ and Edelberg JM: Impaired
angiogenesis in the aged. Sci Aging Knowledge Environ.
2004:pe72004. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
R Core Team, . R: A language and
environment for statistical computing. R Foundation for Statistical
Computing; Vienna: 2023, http://www.R-project.org/
|
|
13
|
Martin P and Nunan R: Cellular and
molecular mechanisms of repair in acute and chronic wound healing.
Br J Dermatol. 173:370–378. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Cai Y, Xiong M, Xin Z, Liu C, Ren J, Yang
X, Lei J, Li W, Liu F, Chu Q, et al: Decoding aging-dependent
regenerative decline across tissues at single-cell resolution. Cell
Stem Cell. 30:1674–1691.e8. 2023. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Arostegui M, Scott RW, Böse K and
Underhill TM: Cellular taxonomy of Hic1+ mesenchymal progenitor
derivatives in the limb: From embryo to adult. Nat Commun.
13:49892022. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Liu M, Zhang L, Marsboom G, Jambusaria A,
Xiong S, Toth PT, Benevolenskaya EV, Rehman J and Malik AB: Sox17
is required for endothelial regeneration following
inflammation-induced vascular injury. Nat Commun. 10:21262019.
View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Perisic Matic L, Rykaczewska U, Razuvaev
A, Sabater-Lleal M, Lengquist M, Miller CL, Ericsson I, Röhl S,
Kronqvist M, Aldi S, et al: Phenotypic modulation of smooth muscle
cells in atherosclerosis is associated with downregulation of
LMOD1, SYNPO2, PDLIM7, PLN, and SYNM. Arterioscler Thromb Vasc
Biol. 36:1947–1961. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Ng SS, De Labastida Rivera F, Yan J,
Corvino D, Das I, Zhang P, Kuns R, Chauhan SB, Hou J, Li XY, et al:
The NK cell granule protein NKG7 regulates cytotoxic granule
exocytosis and inflammation. Nat Immunol. 21:1205–1218. 2020.
View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Zhang X, Yin M and Zhang LJ: Keratin 6, 16
and 17-critical barrier alarmin molecules in skin wounds and
psoriasis. Cells. 8:8072019. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Heinzelmann K, Hu Q, Hu Y, Dobrinskikh E,
Ansari M, Melo-Narváez MC, Ulke HM, Leavitt C, Mirita C, Trudeau T,
et al: Single-cell RNA sequencing identifies G-protein coupled
receptor 87 as a basal cell marker expressed in distal honeycomb
cysts in idiopathic pulmonary fibrosis. Eur Respir J.
59:21023732022. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Veniaminova NA, Vagnozzi AN, Kopinke D, Do
TT, Murtaugh LC, Maillard I, Dlugosz AA, Reiter JF and Wong SY:
Keratin 79 identifies a novel population of migratory epithelial
cells that initiates hair canal morphogenesis and regeneration.
Development. 140:4870–4880. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Rippa AL, Kalabusheva EP and Vorotelyak
EA: Regeneration of dermis: Scarring and cells involved. Cells.
8:6072019. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Driskell RR, Lichtenberger BM, Hoste E,
Kretzschmar K, Simons BD, Charalambous M, Ferron SR, Herault Y,
Pavlovic G, Ferguson-Smith AC and Watt FM: Distinct fibroblast
lineages determine dermal architecture in skin development and
repair. Nature. 504:277–281. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Li Y, Yan H, Guo J, Han Y, Zhang C, Liu X,
Du J and Tian XL: Down-regulated RGS5 by genetic variants impairs
endothelial cell function and contributes to coronary artery
disease. Cardiovasc Res. 117:240–255. 2021. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Bartoschek M and Pietras K: PDGF family
function and prognostic value in tumor biology. Biochem Biophys Res
Commun. 503:984–990. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Kyoreva M, Li Y, Hoosenally M,
Hardman-Smart J, Morrison K, Tosi I, Tolaini M, Barinaga G,
Stockinger B, Mrowietz U, et al: CYP1A1 enzymatic activity
influences skin inflammation via regulation of the AHR pathway. J
Invest Dermatol. 141:1553–1563.e3. 2021. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Qin L, Zhang R, Yang S, Chen F and Shi J:
Knockdown of ANGPTL-4 inhibits inflammatory response and
extracellular matrix accumulation in glomerular mesangial cells
cultured under high glucose condition. Artif Cells Nanomed
Biotechnol. 47:3368–3373. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Ye Y, Yang K, Liu H, Yu Y, Song M, Huang
D, Lei J, Zhang Y, Liu Z, Chu Q, et al: SIRT2 counteracts primate
cardiac aging via deacetylation of STAT3 that silences CDKN2B. Nat
Aging. 3:1269–1287. 2023. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Rolny C, Nilsson I, Magnusson P, Armulik
A, Jakobsson L, Wentzel P, Lindblom P, Norlin J, Betsholtz C,
Heuchel R, et al: Platelet-derived growth factor receptor-beta
promotes early endothelial cell differentiation. Blood.
108:1877–1886. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Stables MJ, Shah S, Camon EB, Lovering RC,
Newson J, Bystrom J, Farrow S and Gilroy DW: Transcriptomic
analyses of murine resolution-phase macrophages. Blood.
118:e192–e208. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Liu Y, Ji Y, Jiang R, Fang C, Shi G, Cheng
L, Zuo Y, Ye Y, Su X, Li J, et al: Reduced smooth
muscle-fibroblasts transformation potentially decreases intestinal
wound healing and colitis-associated cancer in ageing mice. Signal
Transduct Target Ther. 8:2942023. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Bergmeier V, Etich J, Pitzler L, Frie C,
Koch M, Fischer M, Rappl G, Abken H, Tomasek JJ and Brachvogel B:
Identification of a myofibroblast-specific expression signature in
skin wounds. Matrix Biol. 65:59–74. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Lu HP, Lin CJ, Chen WC, Chang YJ, Lin SW,
Wang HH and Chang CJ: TRIM28 regulates Dlk1 expression in
adipogenesis. Int J Mol Sci. 21:72452020. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Khoury LE, Posthumus M, Collins M, van der
Merwe W, Handley C, Cook J and Raleigh SM: ELN and FBN2 gene
variants as risk factors for two sports-related musculoskeletal
injuries. Int J Sports Med. 36:333–337. 2015.PubMed/NCBI
|
|
35
|
Matsusaka T, Katori H, Inagami T, Fogo A
and Ichikawa I: Communication between myocytes and fibroblasts in
cardiac remodeling in angiotensin chimeric mice. J Clin Invest.
103:1451–1458. 1999. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
AlQudah M, Hale TM and Czubryt MP:
Targeting the renin-angiotensin-aldosterone system in fibrosis.
Matrix Biol. 91–92. 92–108. 2020.PubMed/NCBI
|
|
37
|
Zhao J, Bai J, Peng F, Qiu C, Li Y and
Zhong L: USP9X-mediated NRP1 deubiquitination promotes liver
fibrosis by activating hepatic stellate cells. Cell Death Dis.
14:402023. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Guan T, Fang F, Su X, Lin K and Gao Q:
Silencing PEG3 inhibits renal fibrosis in a rat model of diabetic
nephropathy by suppressing the NF-κB pathway. Mol Cell Endocrinol.
513:1108232020. View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Wu W, Zhou S, Fei G and Wang R: The role
of long noncoding RNA MEG3 in fibrosis diseases. Postgrad Med J.
100:529–538. 2024. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Du J, Qian T, Lu Y, Zhou W, Xu X, Zhang C,
Zhang J and Zhang Z: SPARC-YAP/TAZ inhibition prevents the
fibroblasts-myofibroblasts transformation. Exp Cell Res.
429:1136492023. View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Cerezo-Wallis D, Contreras-Alcalde M,
Troulé K, Catena X, Mucientes C, Calvo TG, Cañón E, Tejedo C,
Pennacchi PC, Hogan S, et al: Midkine rewires the melanoma
microenvironment toward a tolerogenic and immune-resistant state.
Nat Med. 26:1865–1877. 2020. View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Hayward S, Gachehiladze M, Badr N,
Andrijes R, Molostvov G, Paniushkina L, Sopikova B, Slobodová Z,
Mgebrishvili G, Sharma N, et al: The CD151-midkine pathway
regulates the immune microenvironment in inflammatory breast
cancer. J Pathol. 251:63–73. 2020. View Article : Google Scholar : PubMed/NCBI
|
|
43
|
Russell CD, Unger SA, Walton M and
Schwarze J: The human immune response to respiratory syncytial
virus infection. Clin Microbiol Rev. 30:481–502. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
44
|
Meng XM, Nikolic-Paterson DJ and Lan HY:
TGF-β: The master regulator of fibrosis. Nat Rev Nephrol.
12:325–338. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
45
|
Lee JH and Massagué J: TGF-β in
developmental and fibrogenic EMTs. Semin Cancer Biol. 86((Pt 2)):
136–145. 2022. View Article : Google Scholar : PubMed/NCBI
|
|
46
|
Morikawa M, Derynck R and Miyazono K:
TGF-β and the TGF-β family: Context-dependent roles in cell and
tissue physiology. Cold Spring Harb Perspect Biol. 8:a0218732016.
View Article : Google Scholar : PubMed/NCBI
|
|
47
|
DiPietro LA: Angiogenesis and wound
repair: When enough is enough. J Leukoc Biol. 100:979–984. 2016.
View Article : Google Scholar : PubMed/NCBI
|
|
48
|
Riggin CN, Weiss SN, Rodriguez AB, Raja H,
Chen M, Schultz SM, Sehgal CM and Soslowsky LJ: Increasing vascular
response to injury improves tendon early healing outcome in aged
rats. Ann Biomed Eng. 50:587–600. 2022. View Article : Google Scholar : PubMed/NCBI
|
|
49
|
Bonham CA, Kuehlmann B and Gurtner GC:
Impaired neovascularization in aging. Adv Wound Care (New
Rochelle). 9:111–126. 2020. View Article : Google Scholar : PubMed/NCBI
|
|
50
|
Eming SA, Martin P and Tomic-Canic M:
Wound repair and regeneration: Mechanisms, signaling, and
translation. Sci Transl Med. 6:265sr62014. View Article : Google Scholar : PubMed/NCBI
|
|
51
|
Fougère B, Boulanger E, Nourhashémi F,
Guyonnet S and Cesari M: Chronic inflammation: Accelerator of
biological aging. J Gerontol A Biol Sci Med Sci. 72:1218–1225.
2017. View Article : Google Scholar : PubMed/NCBI
|
|
52
|
Zhao R, Liang H, Clarke E, Jackson C and
Xue M: Inflammation in chronic wounds. Int J Mol Sci. 17:20852016.
View Article : Google Scholar : PubMed/NCBI
|
|
53
|
Kiritsi D and Nyström A: The role of TGFβ
in wound healing pathologies. Mech Ageing Dev. 172:51–58. 2018.
View Article : Google Scholar : PubMed/NCBI
|
|
54
|
Talbott HE, Mascharak S, Griffin M, Wan DC
and Longaker MT: Wound healing, fibroblast heterogeneity, and
fibrosis. Cell Stem Cell. 29:1161–1180. 2022. View Article : Google Scholar : PubMed/NCBI
|
|
55
|
Zhang J, Zheng Y, Lee J, Hua J, Li S,
Panchamukhi A, Yue J, Gou X, Xia Z, Zhu L and Wu X: A pulsatile
release platform based on photo-induced imine-crosslinking hydrogel
promotes scarless wound healing. Nat Commun. 12:16702021.
View Article : Google Scholar : PubMed/NCBI
|
|
56
|
Lu ZZ, Sun C, Zhang X, Peng Y, Wang Y,
Zeng Y, Zhu N, Yuan Y and Zeng MS: Neuropilin 1 is an entry
receptor for KSHV infection of mesenchymal stem cell through
TGFBR1/2-mediated macropinocytosis. Sci Adv. 9:eadg17782023.
View Article : Google Scholar : PubMed/NCBI
|
|
57
|
Fan J, Zhang X, Jiang Y, Chen L, Sheng M
and Chen Y: SPARC knockdown attenuated TGF-β1-induced fibrotic
effects through Smad2/3 pathways in human pterygium fibroblasts.
Arch Biochem Biophys. 713:1090492021. View Article : Google Scholar : PubMed/NCBI
|
|
58
|
Nagashima G, Suzuki R, Asai JI, Noda M,
Fujimoto M and Fujimoto T: Tissue reconstruction process in the
area of peri-tumoural oedema caused by
glioblastoma-immunohistochemical and graphical analysis using brain
obtained at autopsy. Acta Neurochir Suppl. 86:507–511.
2003.PubMed/NCBI
|
|
59
|
Zhan H, Sun X, Wang X, Gao Q, Yang M, Liu
H, Zheng J, Gong X, Feng S, Chang X and Sun Y: LncRNA MEG3 involved
in NiO NPs-induced pulmonary fibrosis via regulating
TGF-β1-mediated PI3K/AKT pathway. Toxicol Sci. 182:120–131. 2021.
View Article : Google Scholar : PubMed/NCBI
|
|
60
|
O'Reilly S, Tsou PS and Varga J:
Senescence and tissue fibrosis: Opportunities for therapeutic
targeting. Trends Mol Med. 30:1113–1125. 2024. View Article : Google Scholar : PubMed/NCBI
|
|
61
|
Percie du Sert N, Hurst V, Ahluwalia A,
Alam S, Avey MT, Baker M, Browne WJ, Clark A, Cuthill IC, Dirnagl
U, et al: The ARRIVE guidelines 2.0: Updated guidelines for
reporting animal research. PLoS Biol. 18:e30004102020. View Article : Google Scholar : PubMed/NCBI
|
