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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
October-2025 Volume 32 Issue 4

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Activation of toll‑like receptors by non‑coding RNAs and their fragments (Review)

Ruth Ruiz Esparza‑Garrido, Miguel Ángel Velázquez‑Flores
Article Number: 285
Published online on: 11 August 2025

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Article Open Access

ER‑α36 knockdown is associated with lysosomal dysfunction and proliferation inhibition in liver cancer cells

Huanhuan He, Xuan Wang, Zhixuan Wei, An Wang, Xiangyue Fang, Hanbo He, Zhuorui Wu, Xiji Shu, Binlian Sun, Qiongxia Chen, Xuan Huang, Hongyan Zhou, Yuchen Liu, Zhengqi Fu
Article Number: 284
Published online on: 11 August 2025

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Article Open Access

Anti‑inflammatory and anti‑migratory properties of wild‑grape‑derived ε‑viniferin in human endometrial cells: 
A potential therapy for endometriosis

Yinzhi Lin, Yoshikazu Naiki, Shiori Kojima, Masatoshi Hakamata, Hitomi Fukatsu, Yoshiaki Hasegawa, Akihiko Wakatsuki, Naoki Koide, Kazuo Umezawa
Article Number: 283
Published online on: 07 August 2025

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Correction Open Access

[Corrigendum] Propranolol induces hemangioma endothelial cell apoptosis via a p53‑BAX mediated pathway

Tian-Hua Yao, Parekejiang Pataer, Krishna Prasad Regmi, Xi-Wen Gu, Quan-Yan Li, Jing-Ting Du, Su-Meng Ge, Jun-Bo Tu
Article Number: 282
Published online on: 06 August 2025

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Review Open Access

O‑GlcNAcylation: The crosstalk between infection immunity and autophagy in sepsis (Review)

Zhenzhen Huang, Xin Liu, Ling Zhang, Yujie Lin, Xiangli Ma, Peiwu Li
Article Number: 281
Published online on: 04 August 2025

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Article Open Access

Relationship between specific microRNA expression and radioresistant conditions in HL60 acute myeloid leukemia cells

Hikoto Sugiyama, Megumi Kikuchi, Mitsuru Chiba, Yoichiro Hosokawa, Satoru Monzen
Article Number: 280
Published online on: 04 August 2025

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Retraction Open Access

[Retracted] The effect of foxp3‑overexpressing Treg cells on non‑small cell lung cancer cells

Jiangzhou Peng, Zigang Yu, Lei Xue, Jiabin Wang, Jun Li, Degang Liu, Qiang Yang, Yihui Lin
Article Number: 279
Published online on: 04 August 2025

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Article Open Access

Deciphering age‑related differences in wound healing: Insights from the interaction between endothelial cells and fibroblasts

Jianjun Li, Dongzhen Zhu, Mengde Zhang, Zhao Li, Liting Liang, Yuyan Huang, Xu Guo, Yi Kong, Xiaobing Fu, Sha Huang
Article Number: 278
Published online on: 04 August 2025

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Article Open Access

Activation of AKT1 enhances the capacity of senescent BMSCs to regulate osteoclast activation

Chuan Lu, Xingguo Peng, Binbin Zhang, Qi Yan, Bin Dou, Gabriele Karanis, Wenzhuo Gu, Panagiotis Karanis, Kewen Li
Article Number: 277
Published online on: 31 July 2025

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Correction Open Access

[Corrigendum] Cerebral ischemic post‑conditioning induces autophagy inhibition and a HMGB1 secretion attenuation feedback loop to protect against ischemia reperfusion injury in an oxygen glucose deprivation cellular model

Jue Wang, Dong Han, Miao Sun, Juan Feng
Article Number: 276
Published online on: 30 July 2025

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Review Open Access

Mitochondrial‑endoplasmic reticulum crosstalk: Molecular mechanisms and implications for cardiovascular disease (Review)

Yue Liu, Xuejia Gong, Shasha Xing
Article Number: 275
Published online on: 29 July 2025

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Article Open Access

Expression, immunogenicity and clinical significance analysis of thyroid‑stimulating hormone receptor fusion proteins

Xia Chen, Hui Chen
Article Number: 274
Published online on: 29 July 2025

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Retraction Open Access

[Retracted] Expression and clinical significance of hypoxia‑inducible factor 1α, Snail and E‑cadherin in human ovarian cancer cell lines

Yan Zhang, Nina Fan, Jing Yang
Article Number: 273
Published online on: 28 July 2025

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Review

Dual role of hydrogen sulfide in the tumor microenvironment of prostate cancer (Review)

Hua Luo
Article Number: 272
Published online on: 28 July 2025

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Article Open Access

Role of mitochondrial Ca2+ in stroke: From molecular mechanism to treatment strategy (Review)

Yanlin Liu, Wenjie Jin, Huixin Zhou, Xiaomei Wang, Hongbin Ren, Xibing Yang, Kaitao Luo, Xiaobing Dou
Article Number: 271
Published online on: 28 July 2025

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Rev‑erbα: The circadian guardian against NLRP3‑driven liver fibrosis

Junmin Wang, Yanping Wang, Liubing Lin, Wen Pei, Yong Li
Article Number: 270
Published online on: 24 July 2025

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Article Open Access

SIRT5 is associated with asthenozoospermia and regulates GC‑2 spd cell proliferation and apoptosis

Huilin Xing, Shu Chen, Mingxia Wang, Tingting Zheng, Bo Yang
Article Number: 269
Published online on: 23 July 2025

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Article

Regulation of Botulinum neurotoxin half‑life through the ubiquitin‑proteasome system

Hae-Seul Choi, Hye-Rim Seo, Miso Choi, Hwa-Yeong Kim, Sun-Kyu Jin, Myunghoon Lee, Kwang-Hyun Baek
Article Number: 268
Published online on: 23 July 2025

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Article Open Access

Bardoxolone methyl inhibits ferroptosis through the Keap1‑Nrf2 pathway in renal tubular epithelial cells

Soyeon Yoo, Miyeon Kim, Ju Young Bae, Sang Ah Lee, Gwanpyo Koh
Article Number: 267
Published online on: 22 July 2025

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Review Open Access

Role of COUP‑TFII in cardiovascular diseases and colorectal cancer: Insights into the molecular mechanisms and clinical relevance (Review)

Tae-Ho Park, Sang-Heum Han, Jun-Gi Cho, Su-Jeong Park, Jin-Yeong Han, Joo-In Park
Article Number: 266
Published online on: 22 July 2025

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Article Open Access

Role of cellular prion protein in mouse granulosa cells and its effects on ovarian function in knockout mice

Qinyue Cao, Hehua Wang, Jingjing Hu, Yan Wang, Tong Dai, Fen Liu, Xia Yang, Qinyu Yang, Chunhua Tu
Article Number: 265
Published online on: 22 July 2025

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Article Open Access

Role of obesity and estrogen deficiency in non‑alcoholic fatty liver disease: Insights from a mouse model

Aaron Afonso‑Alí, Jano Dicroce‑Giacobini, Silvia Teixido‑Trujillo, Esteban Porrini, José Antonio Pérez‑Pérez, Sonia García‑Hernández, Sergio Luis‑Lima, Beatriz Abrante‑Pérez, Alberto Hernández‑Bustabad, Nieves Guadalupe Acosta‑González, Miriam Iglesias‑Hernández, Laura Díaz‑Martín, Covadonga Rodríguez‑González, Manuel Hernández‑Guerra, Ana Elena Rodríguez‑Rodríguez
Article Number: 264
Published online on: 22 July 2025

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Retraction Open Access

[Retracted] Fisetin inhibits migration, invasion and epithelial‑mesenchymal transition of LMP1‑positive nasopharyngeal carcinoma cells

Rong Li, Yinhai Zhao, Jin Chen, Songjun Shao, Xiujuan Zhang
Article Number: 263
Published online on: 22 July 2025

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Article Open Access

Oxymatrine attenuates pulmonary fibrosis via APE1‑mediated regulation of the PINK1/Parkin pathway

Wenya Xu, Tian Xie, Bingli Zhang, Jie Zhao, Lei Zhang, Yamei Zheng, Yipeng Ding
Article Number: 262
Published online on: 22 July 2025

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Article Open Access

A novel tRNA‑derived small RNA, 5'tiRNA‑Gln‑TTG‑001, aggravates cardiomyocyte inflammatory injury through upregulation of CLIC4

Jing Wang, Yingchun Yi, Bo Han, Li Zhang, Hailin Jia
Article Number: 261
Published online on: 21 July 2025

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Article Open Access

Pan‑cancer analysis of the carcinogenic role of WSB2 in human tumors

Yingzi Deng, Yifei Li, Ruobing Li, Xiaohui Guo, Yan Liu, Shuqing Wang, Juan Zhang, Mi Li, Lina Zhao, Haifeng Cai, Yunfeng Zhang, Fen Hu
Article Number: 260
Published online on: 21 July 2025

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Article Open Access

Differential expression of haematopoietic prostaglandin D synthase by POU2F3‑positive tuft cells in conventional bilayered oncocytic and metaplastic epithelia of Warthin tumours

Kenta Hosomi, Akira Sato, Mitsuaki Ishida, Kensuke Nakanishi, Tetsuya Terada, Shin-Ichi Haginomori, Yoshinobu Hirose, Ko Fujimori
Article Number: 259
Published online on: 17 July 2025

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Review Open Access

Research advances in current drugs targeting hyperlipidemia (Review)

Hanwei Zhao, Yao Wang, Yaqing Li, Ran Cheng, Wenge Chen
Article Number: 258
Published online on: 17 July 2025

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Retraction Open Access

[Retracted] Inhibition of TLR4 protects rat islets against lipopolysaccharide‑induced dysfunction

Xiao Wang, Qin Min Ge, Fan Bian, Yan Dong, Chun Mei Huang
Article Number: 257
Published online on: 16 July 2025

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Journal Cover
February-2026 Volume 33 Issue 2

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

ISX promotes tumor migration and invasion in lung cancer by upregulating COL1A1 in vitro

Yihe Ma, Ye Chen, Yuhui Liang, Yun Huang, Miao Gong, Lifeng Tian, Xiaojun Xiao, Jingyan Liu, Qinmiao Huang
Article Number: 77
Published online on: 31 December 2025

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Article Open Access

Role and mechanism of miR‑222‑5p in endothelial cell apoptosis

Shimeng Wang, Boxin Zhao, Ying Cui, Lin Gui, Jingyao Fan, Lijuan Huang
Article Number: 76
Published online on: 31 December 2025

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Expression of Concern Open Access

[Expression of Concern] MicroRNA-29c inhibits proliferation and promotes apoptosis in non-small cell lung cancer cells by targeting VEGFA

Shijuan Zhan, Chunfeng Wang, Fangqing Yin
Article Number: 75
Published online on: 22 December 2025

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Article Open Access

Melatonin induces autophagy in neuroblastoma by alleviating Pak2‑mediated endoplasmic reticulum stress

Qian-Qi Qiu, Na Zhang, Ying-Yi Xu, Jing-Wen Qin, Gao-Feng Yu, Xing-Rong Song
Article Number: 74
Published online on: 22 December 2025

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Article Open Access

ST3Gal1 modulates intestinal barrier function and impacts human ulcerative colitis

Yin Tian, Yun Liu, Yangyang Shang, Lijian Ran, Li Liu, Rongquan Wang, Jun Ye
Article Number: 73
Published online on: 18 December 2025

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Article Open Access

Mechanistic study of miR‑369‑3p in regulating the Wnt/β‑catenin signaling pathway via targeting SPTBN1 in inflammatory response and bone destruction of rheumatoid arthritis

Aihong Wu, Yuan Wang, Feifei Liu, Zhoufang Cao, Shuhui Du, Mengyu Sun
Article Number: 72
Published online on: 18 December 2025

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Article Open Access

CACNB1 alleviates mepivacaine‑induced myocardial ischemia/reperfusion injury by promoting Nrf2 nuclear translocation

Qingbo Shao, Ji Zhang, Huaying Wang
Article Number: 71
Published online on: 17 December 2025

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Expression of Concern Open Access

[Expression of Concern] Effects of cullin 4B on the proliferation and invasion of human gastric cancer cells

Feng He, Xiu-Mei Cheng, Wen-Long Gu
Article Number: 70
Published online on: 17 December 2025

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Article Open Access

Aggravated effects of human parvovirus B19 NS1 protein on bleomycin‑induced pulmonary fibrosis

Tsai-Ching Hsu, Chih-Chen Tzang, Chia-Wei Kuo, Zhi-Han Wen, Der-Yuan Chen, Bor-Show Tzang
Article Number: 69
Published online on: 16 December 2025

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Review Open Access

Advances regarding the mechanism of endoplasmic reticulum stress in diabetic kidney disease and pharmacological interventions (Review)

Pai Zhang, Yabin Cui, Chunyan Liu, Chengji Cui, Shoulin Zhang, Yue Zhang, Fan Li
Article Number: 68
Published online on: 16 December 2025

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Retraction Open Access

[Retracted] N‑Myc downstream‑regulated gene 2 suppresses the proliferation of T24 human bladder cancer cells via induction of oncosis

Jie Huang, Zhou Wu, Guangxiu Wang, Yingxian Cai, Minshan Cai, Yaozhang Li
Article Number: 67
Published online on: 15 December 2025

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Review Open Access

Deciphering epigenetic regulation in cardiac developmental toxicity: Mechanisms and implications (Review)

Ziling Qin, Ranran Chen, Dianrong Song
Article Number: 66
Published online on: 11 December 2025

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Review Open Access

Gut microbiota as a multifaceted modulator of prostate cancer: Mechanistic insights, therapeutic opportunities and clinical challenges (Review)

Zhenming Hao, Yongqiang Xie, Ru Zhang, Hui Sang, Luxi Li, Yulin Liu, Jinbo Hu, Jijun Wang, Keqiang Chai, Qiang Zhao
Article Number: 65
Published online on: 11 December 2025

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Expression of Concern Open Access

[Expression of Concern] lncRNA FLVCR1‑AS1 drives colorectal cancer progression via modulation of the miR‑381/RAP2A axis

Yi Han, Xiaoyan Wang, Enqiang Mao, Boyong Shen, Liang Huang
Article Number: 64
Published online on: 10 December 2025

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Review Open Access

Influence and treatment of insulin receptor substrate/PI3K/Akt‑mediated insulin resistance in diabetes mellitus (Review)

Weikang Tang, Huixia Liu, Xuan Li, Siyao Deng, Changyu Gao
Article Number: 63
Published online on: 09 December 2025

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Retraction Open Access

[Retracted] Long non‑coding RNA ANRIL knockdown suppresses apoptosis and pro‑inflammatory cytokines while enhancing neurite outgrowth via binding microRNA‑125a in a cellular model of Alzheimer’s disease

Bingling Zhou, Lijuan Li, Xin Qiu, Jiashun Wu, Lei Xu, Wei Shao
Article Number: 62
Published online on: 08 December 2025

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Review Open Access

Mitophagy and oxidative stress in chronic kidney disease (Review)

Quwu Mushuo, Yihuai Tian, Jianchun Li, Yanqin Qiu, Hui Fan, Qiongdan Hu, Qiong Zhang
Article Number: 61
Published online on: 04 December 2025

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Article Open Access

ABCC9 knockdown attenuates isoproterenol‑induced myocardial hypertrophy by inhibiting the PI3K/AKT signaling pathway

Qian Peng, Rui Chang, Linlin Ma, Yanfei Li
Article Number: 60
Published online on: 04 December 2025

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Article

MeCP2 suppresses ferroptosis to drive EMT in retinal pigment epithelial cells: Implications for PVR pathogenesis

Sibei Guo, Yongya Zhang, Xue Li, Xueru Zhao, Yingjuan Liang, Xiaohua Li
Article Number: 59
Published online on: 04 December 2025

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Correction Open Access

[Corrigendum] Screening for implicated genes in colorectal cancer using whole‑genome gene expression profiling

Long-Ci Sun, Hai-Xin Qian
Article Number: 58
Published online on: 04 December 2025

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Article Open Access

Hyperoside prevents osteoporosis by activating the PI3K/AKT signaling pathway to inhibit oxidative stress and promote osteogenesis

Lirong Li, Huaidong Deng, Shabin Zhuan, Boyu Wu, Dawei Xiao
Article Number: 57
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] Interference with Tim‑3 protein expression attenuates the invasion of clear cell renal cell carcinoma and aggravates anoikis

Muming Yu, Bin Lu, Yancun Liu, Ying Me, Lijun Wang, Hui Li
Article Number: 56
Published online on: 01 December 2025

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Article Open Access

Acetylshikonin induces ferroptosis via the lipid peroxidation pathway in osteosarcoma cells

Ji-Ying Chen, Guo-Shou Wang, Tsung-Ming Chang, Ju-Fang Liu
Article Number: 55
Published online on: 27 November 2025

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Review Open Access

Liver X receptor: A potential target for inflammatory bowel disease and colorectal cancer (Review)

Yingjie Li, Xiaoyan Fu, Meiwen Bai, Jiaqi Zhou, Jiatai Qiu, Hongxia Zhang, Shujuan Liang, Meifang Liu
Article Number: 54
Published online on: 27 November 2025

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Article Open Access

lncRNA NEAT1 promotes the proliferation of hemangioma cells by transcriptionally activating β‑catenin via enhancing H3K18 lactylation

Li Yu, Nian Zhou, Xiao-Liang Zhang, Xue-Jing Pang, Lu Xing, Yun-Jing Pu, Li Zhang, Jing-Nan Wu, Hong Shu
Article Number: 53
Published online on: 25 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑206 exerts anti‑oncogenic functions in esophageal squamous cell carcinoma by suppressing the c‑Met/AKT/mTOR pathway

Jin Zhang, Xianen Fa, Qingyong Zhang
Article Number: 52
Published online on: 25 November 2025

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Journal Cover
March-2026 Volume 33 Issue 3

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Interleukin‑6 and ischemic stroke: From mechanisms to clinical prospects (Review)

Xinyue Wang, Xiaohang Zhang, Jianing Lin, Ping Lin
Article Number: 80
Published online on: 05 January 2026

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Article Open Access

Preliminary exploration of the putative function of SF3A2 in clear cell renal cell carcinoma

Ru Chen, Jie Xu
Article Number: 79
Published online on: 05 January 2026

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Retraction Open Access

[Retracted] TIPE‑2 suppresses growth and aggressiveness of hepatocellular carcinoma cells through downregulation of the phosphoinositide 3‑kinase/AKT signaling pathway

Lin Wang, Chen Chen, Shuzhi Feng, Jianli Tian
Article Number: 78
Published online on: 05 January 2026

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