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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

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International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

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Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

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Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

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Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

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Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

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World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

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International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
October-2025 Volume 32 Issue 4

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Journal Metrics

Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Activation of toll‑like receptors by non‑coding RNAs and their fragments (Review)

Ruth Ruiz Esparza‑Garrido, Miguel Ángel Velázquez‑Flores
Article Number: 285
Published online on: 11 August 2025

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ER‑α36 knockdown is associated with lysosomal dysfunction and proliferation inhibition in liver cancer cells

Huanhuan He, Xuan Wang, Zhixuan Wei, An Wang, Xiangyue Fang, Hanbo He, Zhuorui Wu, Xiji Shu, Binlian Sun, Qiongxia Chen, Xuan Huang, Hongyan Zhou, Yuchen Liu, Zhengqi Fu
Article Number: 284
Published online on: 11 August 2025

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Anti‑inflammatory and anti‑migratory properties of wild‑grape‑derived ε‑viniferin in human endometrial cells: 
A potential therapy for endometriosis

Yinzhi Lin, Yoshikazu Naiki, Shiori Kojima, Masatoshi Hakamata, Hitomi Fukatsu, Yoshiaki Hasegawa, Akihiko Wakatsuki, Naoki Koide, Kazuo Umezawa
Article Number: 283
Published online on: 07 August 2025

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Correction Open Access

[Corrigendum] Propranolol induces hemangioma endothelial cell apoptosis via a p53‑BAX mediated pathway

Tian-Hua Yao, Parekejiang Pataer, Krishna Prasad Regmi, Xi-Wen Gu, Quan-Yan Li, Jing-Ting Du, Su-Meng Ge, Jun-Bo Tu
Article Number: 282
Published online on: 06 August 2025

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Review Open Access

O‑GlcNAcylation: The crosstalk between infection immunity and autophagy in sepsis (Review)

Zhenzhen Huang, Xin Liu, Ling Zhang, Yujie Lin, Xiangli Ma, Peiwu Li
Article Number: 281
Published online on: 04 August 2025

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Article Open Access

Relationship between specific microRNA expression and radioresistant conditions in HL60 acute myeloid leukemia cells

Hikoto Sugiyama, Megumi Kikuchi, Mitsuru Chiba, Yoichiro Hosokawa, Satoru Monzen
Article Number: 280
Published online on: 04 August 2025

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Retraction Open Access

[Retracted] The effect of foxp3‑overexpressing Treg cells on non‑small cell lung cancer cells

Jiangzhou Peng, Zigang Yu, Lei Xue, Jiabin Wang, Jun Li, Degang Liu, Qiang Yang, Yihui Lin
Article Number: 279
Published online on: 04 August 2025

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Article Open Access

Deciphering age‑related differences in wound healing: Insights from the interaction between endothelial cells and fibroblasts

Jianjun Li, Dongzhen Zhu, Mengde Zhang, Zhao Li, Liting Liang, Yuyan Huang, Xu Guo, Yi Kong, Xiaobing Fu, Sha Huang
Article Number: 278
Published online on: 04 August 2025

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Article Open Access

Activation of AKT1 enhances the capacity of senescent BMSCs to regulate osteoclast activation

Chuan Lu, Xingguo Peng, Binbin Zhang, Qi Yan, Bin Dou, Gabriele Karanis, Wenzhuo Gu, Panagiotis Karanis, Kewen Li
Article Number: 277
Published online on: 31 July 2025

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Correction Open Access

[Corrigendum] Cerebral ischemic post‑conditioning induces autophagy inhibition and a HMGB1 secretion attenuation feedback loop to protect against ischemia reperfusion injury in an oxygen glucose deprivation cellular model

Jue Wang, Dong Han, Miao Sun, Juan Feng
Article Number: 276
Published online on: 30 July 2025

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Review Open Access

Mitochondrial‑endoplasmic reticulum crosstalk: Molecular mechanisms and implications for cardiovascular disease (Review)

Yue Liu, Xuejia Gong, Shasha Xing
Article Number: 275
Published online on: 29 July 2025

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Article Open Access

Expression, immunogenicity and clinical significance analysis of thyroid‑stimulating hormone receptor fusion proteins

Xia Chen, Hui Chen
Article Number: 274
Published online on: 29 July 2025

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Retraction Open Access

[Retracted] Expression and clinical significance of hypoxia‑inducible factor 1α, Snail and E‑cadherin in human ovarian cancer cell lines

Yan Zhang, Nina Fan, Jing Yang
Article Number: 273
Published online on: 28 July 2025

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Review

Dual role of hydrogen sulfide in the tumor microenvironment of prostate cancer (Review)

Hua Luo
Article Number: 272
Published online on: 28 July 2025

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Role of mitochondrial Ca2+ in stroke: From molecular mechanism to treatment strategy (Review)

Yanlin Liu, Wenjie Jin, Huixin Zhou, Xiaomei Wang, Hongbin Ren, Xibing Yang, Kaitao Luo, Xiaobing Dou
Article Number: 271
Published online on: 28 July 2025

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Rev‑erbα: The circadian guardian against NLRP3‑driven liver fibrosis

Junmin Wang, Yanping Wang, Liubing Lin, Wen Pei, Yong Li
Article Number: 270
Published online on: 24 July 2025

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SIRT5 is associated with asthenozoospermia and regulates GC‑2 spd cell proliferation and apoptosis

Huilin Xing, Shu Chen, Mingxia Wang, Tingting Zheng, Bo Yang
Article Number: 269
Published online on: 23 July 2025

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Article

Regulation of Botulinum neurotoxin half‑life through the ubiquitin‑proteasome system

Hae-Seul Choi, Hye-Rim Seo, Miso Choi, Hwa-Yeong Kim, Sun-Kyu Jin, Myunghoon Lee, Kwang-Hyun Baek
Article Number: 268
Published online on: 23 July 2025

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Bardoxolone methyl inhibits ferroptosis through the Keap1‑Nrf2 pathway in renal tubular epithelial cells

Soyeon Yoo, Miyeon Kim, Ju Young Bae, Sang Ah Lee, Gwanpyo Koh
Article Number: 267
Published online on: 22 July 2025

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Review Open Access

Role of COUP‑TFII in cardiovascular diseases and colorectal cancer: Insights into the molecular mechanisms and clinical relevance (Review)

Tae-Ho Park, Sang-Heum Han, Jun-Gi Cho, Su-Jeong Park, Jin-Yeong Han, Joo-In Park
Article Number: 266
Published online on: 22 July 2025

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Article Open Access

Role of cellular prion protein in mouse granulosa cells and its effects on ovarian function in knockout mice

Qinyue Cao, Hehua Wang, Jingjing Hu, Yan Wang, Tong Dai, Fen Liu, Xia Yang, Qinyu Yang, Chunhua Tu
Article Number: 265
Published online on: 22 July 2025

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Role of obesity and estrogen deficiency in non‑alcoholic fatty liver disease: Insights from a mouse model

Aaron Afonso‑Alí, Jano Dicroce‑Giacobini, Silvia Teixido‑Trujillo, Esteban Porrini, José Antonio Pérez‑Pérez, Sonia García‑Hernández, Sergio Luis‑Lima, Beatriz Abrante‑Pérez, Alberto Hernández‑Bustabad, Nieves Guadalupe Acosta‑González, Miriam Iglesias‑Hernández, Laura Díaz‑Martín, Covadonga Rodríguez‑González, Manuel Hernández‑Guerra, Ana Elena Rodríguez‑Rodríguez
Article Number: 264
Published online on: 22 July 2025

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Retraction Open Access

[Retracted] Fisetin inhibits migration, invasion and epithelial‑mesenchymal transition of LMP1‑positive nasopharyngeal carcinoma cells

Rong Li, Yinhai Zhao, Jin Chen, Songjun Shao, Xiujuan Zhang
Article Number: 263
Published online on: 22 July 2025

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Article Open Access

Oxymatrine attenuates pulmonary fibrosis via APE1‑mediated regulation of the PINK1/Parkin pathway

Wenya Xu, Tian Xie, Bingli Zhang, Jie Zhao, Lei Zhang, Yamei Zheng, Yipeng Ding
Article Number: 262
Published online on: 22 July 2025

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Article Open Access

A novel tRNA‑derived small RNA, 5'tiRNA‑Gln‑TTG‑001, aggravates cardiomyocyte inflammatory injury through upregulation of CLIC4

Jing Wang, Yingchun Yi, Bo Han, Li Zhang, Hailin Jia
Article Number: 261
Published online on: 21 July 2025

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Article Open Access

Pan‑cancer analysis of the carcinogenic role of WSB2 in human tumors

Yingzi Deng, Yifei Li, Ruobing Li, Xiaohui Guo, Yan Liu, Shuqing Wang, Juan Zhang, Mi Li, Lina Zhao, Haifeng Cai, Yunfeng Zhang, Fen Hu
Article Number: 260
Published online on: 21 July 2025

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Article Open Access

Differential expression of haematopoietic prostaglandin D synthase by POU2F3‑positive tuft cells in conventional bilayered oncocytic and metaplastic epithelia of Warthin tumours

Kenta Hosomi, Akira Sato, Mitsuaki Ishida, Kensuke Nakanishi, Tetsuya Terada, Shin-Ichi Haginomori, Yoshinobu Hirose, Ko Fujimori
Article Number: 259
Published online on: 17 July 2025

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Review Open Access

Research advances in current drugs targeting hyperlipidemia (Review)

Hanwei Zhao, Yao Wang, Yaqing Li, Ran Cheng, Wenge Chen
Article Number: 258
Published online on: 17 July 2025

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Retraction Open Access

[Retracted] Inhibition of TLR4 protects rat islets against lipopolysaccharide‑induced dysfunction

Xiao Wang, Qin Min Ge, Fan Bian, Yan Dong, Chun Mei Huang
Article Number: 257
Published online on: 16 July 2025

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Journal Cover
September-2026 Volume 34 Issue 3

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Journal Metrics

Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review

Chronic kidney disease‑associated encephalopathy: Clinical features, pathomechanisms and emerging therapeutic strategies (Review)

Nanling Zeng, Ling Jiang, Yang Zhang, Jian Liu, Qiong Zhang, Lishang Liao, Qiongdan Hu
Article Number: 259
Published online on: 21 July 2026

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Retraction Open Access

[Retracted] Emodin promotes the arrest of human lymphoma Raji cell proliferation through the UHRF1‑DNMT3A‑∆Np73 pathways

Yun Lin, Weiming Chen, Zhihong Wang, Pengwei Cai
Article Number: 258
Published online on: 20 July 2026

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Article Open Access

Sedanolide alleviates LPS‑induced depressive‑like behaviors by modulating the C3a/C3aR signaling axis and microglial glycolysis

Shaocong Lu, Fangla Luo, Niqi Chen, Gongde Shi, Yeru Chen
Article Number: 257
Published online on: 16 July 2026

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Expression of Concern Open Access

[Expression of Concern] Chrysophanol inhibits proliferation and induces apoptosis through NF‑κB/cyclin D1 and NF‑κB/Bcl‑2 signaling cascade in breast cancer cell lines

Li Ren, Zhouping Li, Chunmei Dai, Danyu Zhao, Yanjie Wang, Chunyu Ma, Chun Liu
Article Number: 256
Published online on: 15 July 2026

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Article Open Access

PCSK9 alleviates doxorubicin‑induced pyroptosis of cardiomyocytes

Chaochu Cui, Jinyu Zhao, Xiaoqian Li, Shengming Huang, Gang Liu, Xinhui Xu, Can Guo, Tiesuo Zhao, Jiang Du, Shipeng Li, Xianwei Wang, Jianbo Yang
Article Number: 255
Published online on: 14 July 2026

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Review Open Access

From cell to disease: Regulatory networks and mechanisms of super‑enhancers in aging (Review)

Xiaodan Wang, Weiqian Deng, Shuangxi Tu, Haojun Tang, Kai Yin, Xiao Zhu
Article Number: 254
Published online on: 14 July 2026

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Retraction Open Access

[Retracted] Matrine‑induced apoptosis in Hep3B cells via the inhibition of MDM2

Ning Zhou, Jiequn Li, Ting Li, Guangshun Chen, Zhongqiang Zhang, Zhongzhou Si
Article Number: 253
Published online on: 13 July 2026

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Review Open Access

Role of PANoptosis in the development of gastric immunity and related gastric mucosal disease (Review)

Lan Wang, Zhiyuan Ma, Bei Ji, Shuhui Liu, Shuji Terai, Biguang Tuo, Taolang Li, Xuemei Liu
Article Number: 252
Published online on: 09 July 2026

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Article

Leonurine inhibits the proliferation and metastasis of liver cancer cells by regulating the PI3K/AKT signaling pathway via epithelial‑mesenchymal transition

Bowen Hu, Maher Al Hussan, Jiakai Zhang, Peihao Wen, Changjun Huang, Yang Chen, Huanfei Ding
Article Number: 251
Published online on: 08 July 2026

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Correction Open Access

[Corrigendum] Resistin aggravates the expression of proinflammatory cytokines in cerulein‑stimulated AR42J pancreatic acinar cells

Chong-Yi Jiang, Wei Wang
Article Number: 250
Published online on: 08 July 2026

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Review Open Access

A‑Raf: A serine/threonine protein kinase with important biological functions (Review)

Muhan Yang, Mengying Chen, Jinmei Wei, Yanling Li, Chen Long, Yan Lei, Yanhong Zhou
Article Number: 249
Published online on: 07 July 2026

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Review Open Access

Gut dysbiosis‑derived butyrate loss predicts feeding intolerance: Multiomics evidence guiding nurse‑driven microbiota‑supportive interventions (Review)

Ling Wei, Xiaohua Kong, Yuying Li, Huixia Wu, Yirong Gan, Fang Sun
Article Number: 248
Published online on: 07 July 2026

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Retraction Open Access

[Retracted] Network pharmacology combined with experimental validation to investigate the effect of Rongjin Niantong Fang on chondrocyte apoptosis in knee osteoarthritis

Jun Chen, Ting Zhang, Qingqing Luo, Ruyi Wang, Yuting Dai, Zhenyuan Chen, Chutian Zhang, Xuzheng Chen, Guangwen Wu
Article Number: 247
Published online on: 06 July 2026

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Article Open Access

Laggera alata attenuates LPS‑induced systemic inflammation and hepatic‑pulmonary injury by regulating PINK1/Parkin-associated mitophagy and macrophage polarization

Jiangcun Wei, Wen Zhong, Guangyun Zhou, Mingtao Huang, Xiaodong Huang, Jing Liang
Article Number: 246
Published online on: 02 July 2026

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Review Open Access

Proteolysis‑targeting chimeras in oral squamous cell carcinoma: Current evidence, translational challenges and future directions (Review)

Yun Bai, Danhua Ma, Xi Yang, Min Wang
Article Number: 245
Published online on: 02 July 2026

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Review Open Access

Evolving role of biomarkers beyond prostate‑specific antigen in refining prostate cancer screening: From blood‑based tests to urinary and genetic markers (Review)

Luxi Li, Linyue Zhang, Zehong Li, Keqiang Chai, Weidong Ren
Article Number: 244
Published online on: 02 July 2026

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Article Open Access

Nanocurcumin attenuates brain injury in rats with desert dry‑heat‑induced exertional heat stroke by suppressing TLR4/MyD88/NF‑κB signaling

Lisong Su, Jinquan Qu, Jiajia Li, Wenhui Shi, Laiyang Song, Feixing Liang, Jiangwei Liu
Article Number: 243
Published online on: 02 July 2026

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Review Open Access

TREM2 in glioma: Reprogramming the immune microenvironment from mechanistic understanding to clinical translation (Review)

Junqi Fan, Hongyan Shen, Dan Liu, Songbai Luo, Qingqing Huang, Yi Wen, Libang Yuan
Article Number: 242
Published online on: 02 July 2026

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Article Open Access

Human parvovirus B19 VP1u‑induced osteoclastogenesis is enhanced by RANKL in RAW264.7 macrophage cells

Chun-Yu Lin, Bor-Show Tzang, Yi-Hsuan Lin, Chih-Chen Tzang, Tsai-Ching Hsu
Article Number: 241
Published online on: 30 June 2026

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Retraction Open Access

[Retracted] Anti‑tumor peptide AP25 decreases cyclin D1 expression and inhibits MGC‑803 proliferation via phospho­extracellular signal‑regulated kinase‑, Src‑, c‑Jun N‑terminal kinase‑ and phosphoinositide 3­-kinase‑associated pathways  

Jialiang Hu, Tao Cheng, Lijun Zhang, Beicheng Sun, Lei Deng, Hanmei Xu
Article Number: 240
Published online on: 29 June 2026

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Article Open Access

Aspirin prevents postoperative peritoneal adhesions by inhibiting the TGF‑β1/Smad signaling pathway in rats

Siqi Yan, Yuan Ren, Bingyan Liu, Pai Xiong, Yimin Sun
Article Number: 239
Published online on: 29 June 2026

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Article Open Access

Morinda officinalis oligosaccharides ameliorate corticosterone‑induced depression‑like behaviour in mice by modulating the BDNF signalling pathway and gut microbiota

Mengjie He, Zixuan Liu, Yuxin Chen, Xiaoru Wu, Xueling Dai, Qian Liu, Shuo Wang, Zeping Zuo, Yaxuan Sun
Article Number: 238
Published online on: 29 June 2026

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Journal Cover
October-2026 Volume 34 Issue 4

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Journal Metrics

Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Advances in miR‑200c regulation of apoptosis, pyroptosis and autophagy in disease (Review)

Xiaona Wang, Hua Du, Yingxu Shi
Article Number: 264
Published online on: 28 July 2026

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Review Open Access

Association between periodontitis and heart failure: Mechanisms and clinical implications (Review)

Xinyue Zhang, Xiaoli An
Article Number: 263
Published online on: 28 July 2026

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Article Open Access

Ginsenosides alleviate the progression of hepatic fibrosis by targeting the liver circadian clock gene CLOCK

Jiawen Yu, Chunmei Qian, Renye Que, Yi Zhou
Article Number: 262
Published online on: 28 July 2026

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Retraction Open Access

[Retracted] PPM1A as a key target of the application of Jiawei‑Maxing‑Shigan decoction for the attenuation of radiation‑induced epithelial‑mesenchymal transition in type II alveolar epithelial cells

Jinhua Lu, Shengyou Lin, Zechen Lin, Xianlei Lin, Yuezhong Shen, Jingyang Su
Article Number: 261
Published online on: 27 July 2026

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Article Open Access

UBE2A as a prognostic indicator across human cancers: Insights from multi‑omics and immune landscape analyses

Yun Wen, Pengfei Luo
Article Number: 260
Published online on: 23 July 2026

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