|
1
|
Costa J, Mackay R, De Aguiar Greca SC,
Corti A, Silva E, Karteris E and Ahluwalia A: The role of the 3Rs
for understanding and modeling the human placenta. J Clin Med.
10:34442021. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Herrick EJ and Bordoni B: Embryology,
placenta. StatPearls (Internet). StatPearls Publishing; Treasure
Island, FL: 2023, https://www.ncbi.nlm.nih.gov/books/NBK551634/November
11–2024
|
|
3
|
Romere C, Duerrschmid C, Bournat J,
Constable P, Jain M, Xia F, Saha PK, Del Solar M, Zhu B, York B, et
al: Asprosin, a fasting-induced glucogenic protein hormone. Cell.
165:566–579. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Shabir K, Brown JE, Afzal I, Gharanei S,
Weickert MO, Barber TM, Kyrou I and Randeva HS: Asprosin, a novel
pleiotropic adipokine implicated in fasting and obesity-related
cardio-metabolic disease: Comprehensive review of preclinical and
clinical evidence. Cytokine Growth Factor Rev. 60:120–132. 2021.
View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Kerslake R, Hall M, Vagnarelli P,
Jeyaneethi J, Randeva H, Pados G, Kyrou I and Karteris E: A
pancancer overview of FBN1, asprosin and its cognate receptor OR4M1
with detailed expression profiling in ovarian cancer. Oncol Lett.
22:6502021. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Shabir K, Gharanei S, Orton S, Patel V,
Chauhan P, Karteris E, Randeva HS, Brown JE and Kyrou I: Asprosin
exerts pro-inflammatory effects in THP-1 macrophages mediated via
the Toll-like Receptor 4 (TLR4) pathway. Int J Mol Sci. 24:2272022.
View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Lee T, Yun S, Jeong JH and Jung TW:
Asprosin impairs insulin secretion in response to glucose and
viability through TLR4/JNK-mediated inflammation. Mol Cell
Endocrinol. 486:96–104. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Mishra I, Xie WR, Bournat JC, He Y, Wang
C, Silva ES, Liu H, Ku Z, Chen Y, Erokwu BO, et al: Protein
tyrosine phosphatase receptor δ serves as the orexigenic asprosin
receptor. Cell Metab. 34:549–563.e8. 2022. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Orton S, Karkia R, Mustafov D, Gharanei S,
Braoudaki M, Filipe A, Panfilov S, Saravi S, Khan N, Kyrou I, et
al: In silico and in vitro mapping of receptor-type protein
tyrosine phosphatase receptor type D in health and disease:
Implications for asprosin signalling in endometrial cancer and
neuroblastoma. Cancers (Basel). 16:5822024. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Ozturk HA and Arici FN: Achilles tendon
thickness and serum asprosin level significantly increases in
patients with polycystic ovary syndrome. PeerJ. 12:e179052024.
View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Boz İB, Aytürk Salt S, Salt Ö, Sayın NC
and Dibirdik İ: Association between plasma asprosin levels and
gestational diabetes mellitus. Diabetes Metab Syndr Obes.
16:2515–2521. 2023. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Shafi N, Bano F and Uraneb S: The role of
novel hormone asprosin in insulin resistance during preeclampsia.
Pak J Pharm Sci. 34 (Suppl 3):1039–1043. 2021.PubMed/NCBI
|
|
13
|
Banerjee A, Vishesh C, Anamika Tripathy M
and Umesh R: Asprosin-mediated regulated of ovarian functions in
mice: An age-dependent study. Peptides. 181:1712932024. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Msheik H, El Hayek S, Bari MF, Azar J,
Abou-Kheir W, Kobeissy F, Vatish M and Daoud G: Transcriptomic
profiling of trophoblast fusion using BeWo and JEG-3 cell lines.
Mol HumReprod. 25:811–824. 2019.
|
|
15
|
Morea A, Saravi S, Sisu C, Hall M, Tosi S,
Karteris E and Storlazzi CT: Effect of MYC and PARP inhibitors in
ovarian cancer using an In-Vitro model. Anticancer Res.
44:1817–1827. 2024. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
FunRich, . Functional Enrichment Analysis
Tool. http://www.funrich.org/December
28–2024
|
|
17
|
BigOmics Analytics, . Omics Analysis
Software. BigOmics Analytics SA; Lugano: 2019, https://bigomics.ch/December 28–2024
|
|
18
|
Chen Y and Wang X: miRDB: An online
database for prediction of functional microRNA targets. Nucleic
Acids Res. 48:D127–D131. 2020. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Agarwal V, Bell GW, Nam JW and Bartel DP:
Predicting effective microRNA target sites in mammalian mRNAs.
Elife. 4:e050052015. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Li JH, Liu S, Zhou H, Qu LH and Yang JH:
starBase v2.0: Decoding miRNA-ceRNA, miRNA-ncRNA and protein-RNA
interaction networks from large-scale CLIP-Seq data. Nucleic Acids
Res. 42:D92–D97. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Pathan M, Keerthikumar S, Ang CS, Gangoda
L, Quek CY, Williamson NA, Mouradov D, Sieber OM, Simpson RJ, Salim
A, et al: FunRich: An open access standalone functional enrichment
and interaction network analysis tool. Proteomics. 15:2597–2601.
2015. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Szklarczyk D, Kirsch R, Koutrouli M,
Nastou K, Mehryary F, Hachilif R, Gable AL, Fang T, Doncheva NT,
Pyysalo S, et al: The STRING database in 2023: Protein-protein
association networks and functional enrichment analyses for any
sequenced genome of interest. Nucleic Acids Res. 51:D638–D646.
2023. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Arutyunyan A, Roberts K, Troulé K, Wong
FCK, Sheridan MA, Kats I, Garcia-Alonso L, Velten B, Hoo R,
Ruiz-Morales ER, et al: Spatial multiomics map of trophoblast
development in early pregnancy. Nature. 616:143–151. 2023.
View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Burleigh DW, Kendziorski CM, Choi YJ,
Grindle KM, Grendell RL, Magness RR and Golos TG: Microarray
analysis of BeWo and JEG3 trophoblast cell lines: Identification of
differentially expressed transctripts. Placenta. 28:383–389. 2007.
View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Lynch CS, Kennedy VC, Tanner AR, Ali A,
Winger QA, Rozance PJ and Anthony RV: Impact of placental SLC2A3
deficiency during the first-half of gestation. Int J Mol Sci.
23:125302022. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Tan VP and Miyamoto S: HK2/hexokinase-II
integrates glycolysis and autophagy to confer cellular protection.
Autophagy. 11:963–964. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Song TR, Su GD, Chi YL, Wu T, Xu Y and
Chen CC: Dysregu-lated miRNAs contribute to altered placental
glucose metabolism in patients with gestational diabetes via
targeting GLUT1 and HK2. Placenta. 105:14–22. 2021. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Lai R, Ji L, Zhang X, Xu Y, Zhong Y, Chen
L, Hu H and Wang L: Stanniocalcin2 inhibits the
epithelial-mesenchymal transition and invasion of trophoblasts via
activation of autophagy under high-glucose conditions. Mol Cell
Endocrinol. 547:1115982022. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Mparmpakas D, Zachariades E, Goumenou A,
Gidron Y and Karteris E: Placental DEPTOR as a stress sensor during
pregnancy. Clin Sci (Lond). 122:349–359. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Mparmpakas D, Zachariades E, Foster H,
Kara A, Harvey A, Goumenou A and Karteris E: Expression of mTOR and
downstream signalling components in the JEG-3 and BeWo human
placental choriocarcinoma cell lines. Int J Mol Med. 25:65–69.
2010.PubMed/NCBI
|
|
31
|
Yang J, Zhang Y, Tong J, Lv H, Zhang C and
Chen ZJ: Dysfunction of DNA damage-inducible transcript 4 in the
decidua is relevant to the pathogenesis of preeclampsia. Biol
Reprod. 98:821–833. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Orioli L, Canouil M, Sawadogo K, Ning L,
Deldicque L, Lause P, de Barsy M, Froguel P, Loumaye A, Deswysen Y,
et al: Identification of myokines susceptible to improve glucose
homeostasis after bariatric surgery. Eur J Endocrinol. 189:409–421.
2023. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Pooley RD, Moynihan KL, Soukoulis V, Reddy
S, Francis R, Lo C, Ma LJ and Bader DM: Murine CENPF interacts with
syntaxin 4 in the regulation of vesicular transport. J Cell Sci.
121:3413–3421. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Vivot K, Moullé VS, Zarrouki B, Tremblay
C, Mancini AD, Maachi H, Ghislain J and Poitout V: The regulator of
G-protein signaling RGS16 promotes insulin secretion and β-cell
proliferation in rodent and human islets. Mol Metab. 26:988–996.
2016. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Gou R and Zhang X: Glycolysis: A fork in
the path of normal and pathological pregnancy. FASEB J.
37:e232632023. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Lu X, Lan X, Fu X, Li J, Wu M, Xiao L and
Zeng Y: Screening preeclampsia genes and the effects of CITED2 on
trophoblastic function. Int J Gen Med. 17:3493–3509. 2024.
View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Lyu C, Ni T, Guo Y, Zhou T, Chen ZJ, Yan J
and Li Y: Insufficient GDF15 expression predisposes women to
unexplained recurrent pregnancy loss by impairing extravillous
trophoblast invasion. Cell Prolif. 56:e135142023. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Xu B, Chen X, Ding Y, Chen C, Liu T and
Zhang H: Abnormal angiogenesis of placenta in progranulin-deficient
mice. Mol Med Rep. 22:3482–3492. 2020.PubMed/NCBI
|
|
39
|
Shibuya M: Vascular endothelial growth
factor (VEGF) and its receptor (VEGFR) signaling in angiogenesis: A
crucial target for anti- and pro-angiogenic therapies. Genes
Cancer. 2:1097–1105. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Marini M, Vichi D, Toscano A, Thyrion GD,
Bonaccini L, Parretti E, Gheri G, Pacini A and Sgambati E: Effect
of impaired glucose tolerance during pregnancy on the expression of
VEGF receptors in human placenta. Reprod Fertil Dev. 20:789–801.
2008. View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Molè MA, Coorens THH, Shahbazi MN,
Weberling A, Weatherbee BAT, Gantner CW, Sancho-Serra C, Richardson
L, Drinkwater A, Syed N, et al: A single cell characterisation of
human embryogenesis identifies pluripotency transitions and
putative anterior hypoblast centre. Nat Commun. 12:36792021.
View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Zhang Z, Tan Y, Zhu L, Zhang B, Feng P,
Gao E, Xu C, Wang X, Yi W and Sun Y: Asprosin improves the survival
of mesenchymal stromal cells in myocardial infarction by inhibiting
apoptosis via the activated ERK1/2-SOD2 pathway. Life Sci.
231:1165542019. View Article : Google Scholar : PubMed/NCBI
|
|
43
|
Lu Y, Liu C, Pang X, Chen X, Wang C and
Huang H: Bioinformatic identification of signature miRNAs
associated with fetoplacental vascular dysfunction in gestational
diabetes mellitus. Biochem Biophys Reps. 41:1018882024.PubMed/NCBI
|
|
44
|
Zhong L, Long Y, Wang S, Lian R, Deng L,
Ye Z, Wang Z and Liu B: Continuous elevation of plasma asprosin in
pregnant women complicated with gestational diabetes mellitus: A
nested case-control study. Placenta. 93:17–22. 2020. View Article : Google Scholar : PubMed/NCBI
|
|
45
|
Hoffmann T, Morcos YAT, Janoschek R,
Turnwald EM, Gerken A, Müller A, Sengle G, Dötsh J, Appel S and
Hucklenbruch-Rother E: Correlation of metabolic characteristics
with maternal, fetal and placental asprosin in human pregnancy.
Endocr Connect. 11:e2200692022. View Article : Google Scholar : PubMed/NCBI
|
|
46
|
Barboza R, Lima FA, Reis AS, Murillo OJ,
Peixoto EPM, Bandeira CL, Fotoran WL, Sardinha LR, Wunderlich G,
Bevilacqua E, et al: TLR4-mediated placental pathology and
pregnancy outcome in experimental malaria. Sci Rep. 7:86232017.
View Article : Google Scholar : PubMed/NCBI
|
|
47
|
Zhang Y, Liu W, Zhong Y, Li Q, Wu M, Yang
L, Liu X and Zou L: Metformin corrects glucose metabolism
reprogramming and NLRP3 inflammasome-induced pyroptosis via
inhibiting the TLR4/NF-κβ/PFKFB3 signaling in trophoblasts:
Implication for a potential therapy of preeclampsia. Oxid Med Cell
Longev. 2021:18063442021. View Article : Google Scholar : PubMed/NCBI
|
|
48
|
Zhou J, Bai J, Guo Y, Fu L and Xing J:
Higher levels of triglyceride, fatty acid translocase, and
toll-like receptor 4 and lower level of HDL-C in pregnant women
with GDM and their close correlation with neonatal weight. Gynecol
Obstet Invest. 86:48–54. 2021. View Article : Google Scholar : PubMed/NCBI
|
|
49
|
Batalha IM, Maylem ERS, Spicer LJ, Pena
Bello CA, Archilia EC and Shütz LF: Effects of asprosin on
estradiol and progesterone secretion and proliferation of bovine
granulosa cells. Mol Cell Endocrinol. 565:1118902023. View Article : Google Scholar : PubMed/NCBI
|
|
50
|
Vasu S, Kumano K, Darden CM, Rahman I,
Lawrence MC and Naziruddin B: MicroRNA signatures as future
biomarkers for diagnosis of diabetes states. Cells. 8:15332019.
View Article : Google Scholar : PubMed/NCBI
|
|
51
|
Atkin SL, Ramachandran V, Yousri NA,
Benurwar M, Simper SC, McKinlay R, Adams TD, Najafi-Shoushtari SH
and Hunt SC: Changes in blood microRNA expression and early
metabolic responsiveness 21 days following bariatric surgery. Front
Endocrinol (Lausanne). 9:7732019. View Article : Google Scholar : PubMed/NCBI
|
|
52
|
Chen M and Yan J: A preliminary integrated
analysis of miRNA-mRNA expression profiles reveals a role of
miR-146a-3p/TRAF6 in plasma from gestational diabetes mellitus
patients. Ginekol Pol. 95:627–635. 2024.PubMed/NCBI
|
|
53
|
Oğlak SC, Aşir F, Yılmaz EZ, Bolluk G,
Korak T and Ağaçayak E: The immunohistochemical and bioinformatics
analysis of the placental expressions of vascular cell adhesion
protein 1 (VCAM-1) and high mobility group box 1 (HMGB1) proteins
in gestational diabetic mothers. Z Geburtshilfe Neonatol.
229:90–98. 2025. View Article : Google Scholar : PubMed/NCBI
|
|
54
|
Yanai S, Tokuhara D, Tachibana D, Saito M,
Sakashita Y, Shintaku H and Koyama M: Diabetic pregnancy activates
the innate immune response through TLR5 or TLR1/2 on neonatal
monocyte. J Reprod Immunol. 117:17–23. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
55
|
Li QP, Pereira TJ, Moyce BL, Mahood TH,
Doucette CA, Rempel J and Dolinsky VW: In utero exposure to
gestational diabetes mellitus conditions TLR4 and TLR2 activated
IL-1beta responses in spleen cells from rat offspring. Biochim
Biophys Acta. 1862:2137–2146. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
56
|
Shi H, Kokoeva MV, Inouye K, Tzameli I,
Yin H and Flier JS: TLR4 links innate immunity and fatty
acid-induced insulin resistance. J Clin Invest. 116:3015–3025.
2006. View Article : Google Scholar : PubMed/NCBI
|
