|
1
|
Gao HX, Regier EE and Close KL:
International diabetes federation world diabetes Congress 2015. J
Diabetes. 8:300–302. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Carballido-Gamio J: Imaging techniques to
study diabetic bone disease. Curr Opin Endocrinol Diabetes Obes.
29:350–360. 2022. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Liu X, Chen F, Liu L and Zhang Q:
Prevalence of osteoporosis in patients with diabetes mellitus: A
systematic review and meta-analysis of observational studies. BMC
Endocr Disord. 23:12023. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Schacter GI and Leslie WD: Diabetes and
osteoporosis: Part I, epidemiology and pathophysiology. Endocrinol
Metab Clin North Am. 50:275–228. 20215. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Vilaca T, Schini M, Harnan S, Sutton A,
Poku E, Allen IE, Cummings SR and Eastell R: The risk of hip and
non-vertebral fractures in type 1 and type 2 diabetes: A systematic
review and meta-analysis update. Bone. 137:1154572020. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Asadipooya K and UY EM: Advanced glycation
end products (AGEs), receptor for AGEs, diabetes, and bone: Review
of the literature. J Endocr Soc. 3:1799–1818. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Yamagishi S: Role of advanced glycation
end products (AGEs) in osteoporosis in diabetes. Curr Drug Targets.
12:2096–2102. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Lee HS and Hwang JS: Impact of type 2
diabetes mellitus and antidiabetic medications on bone metabolism.
Curr Diab Rep. 20:782020. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Napoli N, Chandran M, Pierroz DD,
Abrahamsen B, Schwartz AV and Ferrari SL; IOF Bone and Diabetes
Working Group, : Mechanisms of diabetes mellitus-induced bone
fragility. Nat Rev Endocrinol. 13:208–219. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Jankovic J: Complications and limitations
of drug therapy for Parkinson's disease. Neurology. 55 (12 Suppl
6):S2–S6. 2000.PubMed/NCBI
|
|
11
|
Pietschmann P, Patsch JM and Schernthaner
G: Diabetes and bone. Horm Metab Res. 42:763–768. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Holstege A: Long-term drug treatments to
improve prognosis of patients with liver cirrhosis and to prevent
complications due to portal hypertension. Z Gastroenterol.
57:983–996. 2019.(In German). PubMed/NCBI
|
|
13
|
Huang KC, Chuang PY, Yang TY, Tsai YH, Li
YY and Chang SF: Diabetic rats induced using a high-fat diet and
low-dose streptozotocin treatment exhibit gut microbiota dysbiosis
and osteoporotic bone pathologies. Nutrients. 16:12202024.
View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Boyar H, Turan B and Severcan F: FTIR
spectroscopic investigation of mineral structure of streptozotocin
induced diabetic rat femur and tibia. Spectroscopy. 17:627–633.
2003. View Article : Google Scholar
|
|
15
|
Lu R, Zheng Z, Yin Y and Jiang Z:
Genistein prevents bone loss in type 2 diabetic rats induced by
streptozotocin. Food Nutr Res. 64:10.29219/fnr.v64.3666. 2020.
View Article : Google Scholar
|
|
16
|
Wu X, Gong H, Hu X, Shi P, Cen H and Li C:
Effect of verapamil on bone mass, microstructure and mechanical
properties in type 2 diabetes mellitus rats. BMC Musculoskelet
Disord. 23:3632022. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Ghodsi R and Kheirouri S: Carnosine and
advanced glycation end products: A systematic review. Amino Acids.
50:1177–1186. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Corona C, Frazzini V, Silvestri E,
Lattanzio R, La Sorda R, Piantelli M, Canzoniero LM, Ciavardelli D,
Rizzarelli E and Sensi SL: Effects of dietary supplementation of
carnosine on mitochondrial dysfunction, amyloid pathology, and
cognitive deficits in 3×Tg-AD mice. PLoS One. 6:e179712011.
View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Jukić I, Kolobarić N, Stupin A, Matić A,
Kozina N, Mihaljević Z, Mihalj M, Šušnjara P, Stupin M, Ćurić ŽB,
et al: Carnosine, small but mighty-prospect of use as functional
ingredient for functional food formulation. Antioxidants (Basel).
10:10372021. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Ko EA, Park YJ, Yoon DS, Lee KM, Kim J,
Jung S, Lee JW and Park KH: Drug repositioning of polaprezinc for
bone fracture healing. Commun Biol. 5:4622022. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Busa P, Lee SO, Huang N, Kuthati Y and
Wong CS: Carnosine alleviates knee osteoarthritis and promotes
synoviocyte protection via activating the Nrf2/HO-1 signaling
pathway: An in-vivo and in-vitro study. Antioxidants (Basel).
11:12092022. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Huang T, Yan G and Guan M: Zinc
homeostasis in bone: Zinc transporters and bone diseases. Int J Mol
Sci. 21:12362020. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Kheirouri S, Alizadeh M and Maleki V: Zinc
against advanced glycation end products. Clin Exp Pharmacol
Physiol. 45:491–498. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Marreiro DD, Cruz KJ, Morais JB, Beserra
JB, Severo JS and de Oliveira AR: Zinc and oxidative stress:
Current mechanisms. Antioxidants (Basel). 6:242017. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Brzóska MM and Rogalska J: Protective
effect of zinc supplementation against cadmium-induced oxidative
stress and the RANK/RANKL/OPG system imbalance in the bone tissue
of rats. Toxicol Appl Pharmacol. 272:208–220. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Bartmański M, Pawłowski Ł, Knabe A, Mania
S, Banach-Kopeć A, Sakowicz-Burkiewicz M and Ronowska A: The effect
of marginal Zn(2+) excess released from titanium coating on
differentiation of human osteoblastic cells. ACS Appl Mater
Interfaces. 16:48412–48427. 2024. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Shiota J, Tagawa H, Izumi N, Higashikawa S
and Kasahara H: Effect of zinc supplementation on bone formation in
hemodialysis patients with normal or low turnover bone. Ren Fail.
37:57–60. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Saito M and Marumo K: Collagen cross-links
as a determinant of bone quality: A possible explanation for bone
fragility in aging, osteoporosis, and diabetes mellitus. Osteoporos
Int. 21:195–214. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Yudhani RD, Pakha DN, Wiyono N and Wasita
B: Molecular mechanisms of zinc in alleviating obesity: Recent
updates (Review). World Acad Sci J. 6:702024. View Article : Google Scholar
|
|
30
|
Gao X, Al-Baadani MA, Wu M, Tong N, Shen
X, Ding X and Liu J: Study on the local anti-osteoporosis effect of
polaprezinc-loaded antioxidant electrospun membrane. Int J
Nanomedicine. 17:17–29. 2022. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
An Y, Zhang H, Wang C, Jiao F, Xu H, Wang
X, Luan W, Ma F, Ni L, Tang X, et al: Activation of
ROS/MAPKs/NF-κB/NLRP3 and inhibition of efferocytosis in
osteoclast-mediated diabetic osteoporosis. FASEB J.
33:12515–201927. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Li M, Sun Z, Zhang H and Liu Z: Recent
advances on polaprezinc for medical use (Review). Exp Ther Med.
22:14452021. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Furman BL: Streptozotocin-induced diabetic
models in mice and rats. Curr Protoc Pharmacol. 70:5.47.1–5.20.
2015.PubMed/NCBI
|
|
34
|
Furman BL: Streptozotocin-induced diabetic
models in mice and rats. Curr Protoc. 1:e782021. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Islam MS and Loots DT: Experimental rodent
models of type 2 diabetes: A review. Methods Find Exp Clin
Pharmacol. 31:249–261. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Amri J, Alaee M, Babaei R, Salemi Z,
Meshkani R, Ghazavi A, Akbari A and Salehi M: Biochanin-A has
antidiabetic, antihyperlipidemic, antioxidant, and protective
effects on diabetic nephropathy via suppression of TGF-β1 and PAR-2
genes expression in kidney tissues of STZ-induced diabetic rats.
Biotechnol Appl Biochem. 69:2112–2121. 2022. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Muhammad HJ, Shimada T, Fujita A and Sai
Y: Sodium citrate buffer improves pazopanib solubility and
absorption in gastric acid-suppressed rat model. Drug Metab
Pharmacokinet. 55:1009952024. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Krebs H: Citric acid cycle: A chemical
reaction for life. Nurs Mirror. 149:30–32. 1979.PubMed/NCBI
|
|
39
|
Sun Q, Tian FM, Liu F, Fang JK, Hu YP,
Lian QQ, Zhou Z and Zhang L: Denosumab alleviates intervertebral
disc degeneration adjacent to lumbar fusion by inhibiting endplate
osteochondral remodeling and vertebral osteoporosis in
ovariectomized rats. Arthritis Res Ther. 23:1522021. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Livák F and Petrie HT: Somatic generation
of antigen-receptor diversity: A reprise. Trends Immunol.
22:608–612. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Tsuji-Naito K: Aldehydic components of
cinnamon bark extract suppresses RANKL-induced osteoclastogenesis
through NFATc1 downregulation. Bioorg Med Chem. 16:9176–9183. 2008.
View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Matsui S, Hiraishi C, Sato R, Kojima T,
Matoba K, Fujimoto K and Yoshida H: Association of metformin
administration with the serum levels of zinc and homocysteine in
patients with type 2 diabetes: A cross-sectional study. Diabetol
Int. 16:394–402. 2025. View Article : Google Scholar : PubMed/NCBI
|
|
43
|
Goyal SN, Reddy NM, Patil KR, Nakhate KT,
Ojha S, Patil CR and Agrawal YO: Challenges and issues with
streptozotocin-induced diabetes-A clinically relevant animal model
to understand the diabetes pathogenesis and evaluate therapeutics.
Chem Biol Interact. 244:49–63. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
44
|
El Dib R, Gameiro OL, Ogata MS, Módolo NS,
Braz LG, Jorge EC, do Nascimento P Jr and Beletate V: Zinc
supplementation for the prevention of type 2 diabetes mellitus in
adults with insulin resistance. Cochrane Database Syst Rev.
2015:CD0055252015.PubMed/NCBI
|
|
45
|
Sureshkumar K, Durairaj M, Srinivasan K,
Goh2 KW, Undela K, Mahalingam VT, Ardianto C, Ming LC and Ganesan
RM: Effect of L-carnosine in patients with age-related diseases: A
systematic review and meta-analysis. Front Biosci (Landmark Ed).
28:182023. View Article : Google Scholar : PubMed/NCBI
|
|
46
|
Cararo JH, Streck EL, Schuck PF and
Ferreira Gda C: Carnosine and related peptides: Therapeutic
potential in age-related disorders. Aging Dis. 6:369–379. 2015.
View Article : Google Scholar : PubMed/NCBI
|
|
47
|
Yamaguchi M and Ehara Y: Zinc decrease and
bone metabolism in the femoral-metaphyseal tissues of rats with
skeletal unloading. Calcif Tissue Int. 57:218–223. 1995. View Article : Google Scholar : PubMed/NCBI
|
|
48
|
Sugiyama T, Tanaka H and Kawai S:
Improvement of periarticular osteoporosis in postmenopausal women
with rheumatoid arthritis by beta-alanyl-L-histidinato zinc: A
pilot study. J Bone Miner Metab. 18:335–338. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
49
|
Kato H, Ochiai-Shino H, Onoder S, Saito A,
Shibahara T and Azuma T: Promoting effect of 1,25(OH)2 vitamin D3
in osteogenic differentiation from induced pluripotent stem cells
to osteocyte-like cells. Open Biol. 5:1402012015. View Article : Google Scholar : PubMed/NCBI
|
|
50
|
Seo HJ, Cho YE, Kim T, Shin H and Kwun IS:
Zinc may increase bone formation through stimulating cell
proliferation, alkaline phosphatase activity and collagen synthesis
in osteoblastic MC3T3-E1 cells. Nutr Res Pract. 4:356–361. 2010.
View Article : Google Scholar : PubMed/NCBI
|
|
51
|
Yamaguchi M, Goto M, Uchiyama S and
Nakagawa T: Effect of zinc on gene expression in osteoblastic
MC3T3-E1 cells: Enhancement of Runx2, OPG, and regucalcin mRNA
expressions. Mol Cell Biochem. 312:157–166. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
52
|
Yang Y, Wang Y, Kong Y, Zhang X, Zhang H,
Gang Y and Bai L: Carnosine prevents type 2 diabetes-induced
osteoarthritis through the ROS/NF-κB pathway. Front Pharmacol.
9:5982018. View Article : Google Scholar : PubMed/NCBI
|
|
53
|
Yamaguchi M and Uchiyama S: Receptor
activator of NF-kappaB ligand-stimulated osteoclastogenesis in
mouse marrow culture is suppressed by zinc in vitro. Int J Mol Med.
14:81–85. 2004.PubMed/NCBI
|
|
54
|
Thomas S and Jaganathan BG: Signaling
network regulating osteogenesis in mesenchymal stem cells. J Cell
Commun Signal. 16:47–61. 2022. View Article : Google Scholar : PubMed/NCBI
|
|
55
|
Amarasekara DS, Kim S and Rho J:
Regulation of osteoblast differentiation by cytokine networks. Int
J Mol Sci. 22:28512021. View Article : Google Scholar : PubMed/NCBI
|
|
56
|
Lin W, Hu S, Li K, Shi Y, Pan C, Xu Z, Li
D, Wang H, Li B and Chen H: Breaking osteoclast-acid vicious cycle
to rescue osteoporosis via an acid responsive organic
framework-based neutralizing and gene editing platform. Small.
20:e23075952024. View Article : Google Scholar : PubMed/NCBI
|
|
57
|
Amin N, Clark CCT, Taghizadeh M and
Djafarnejad S: Zinc supplements and bone health: The role of the
RANKL-RANK axis as a therapeutic target. J Trace Elem Med Biol.
57:1264172020. View Article : Google Scholar : PubMed/NCBI
|
|
58
|
Molenda M and Kolmas J: The role of zinc
in bone tissue health and regeneration-a review. Biol Trace Elem
Res. 201:5640–5651. 2023. View Article : Google Scholar : PubMed/NCBI
|
|
59
|
Ono T, Hayashi M, Sasaki F and Nakashima
T: RANKL biology: Bone metabolism, the immune system, and beyond.
Inflamm Regen. 40:22020. View Article : Google Scholar : PubMed/NCBI
|
|
60
|
Boyce BF and Xing L: Functions of
RANKL/RANK/OPG in bone modeling and remodeling. Arch Biochem
Biophys. 473:139–146. 2008. View Article : Google Scholar : PubMed/NCBI
|
