|
1
|
Kotseva K, Jennings C, Bassett P, Adamska
A, Hobbs R and Wood D; ASPIRE-3-PREVENT Investigators, : Challenge
of cardiovascular prevention in primary care: Achievement of
lifestyle, blood pressure, lipids and diabetes targets for primary
prevention in England-results from ASPIRE-3-PREVENT cross-sectional
survey. Open Heart. 11:e0027042024. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Han S, Kim NR, Kang JW, Eun JS and Kang
YM: Radial BMD and serum CTX–I can predict the progression of
carotid plaque in rheumatoid arthritis: A 3-year prospective cohort
study. Arthritis Res Ther. 23:2582021. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Zheng L, Than A, Zan P, Li D, Zhang Z,
Leow MKS and Chen P: Mild-photothermal and nanocatalytic therapy
for obesity and associated diseases. Theranostics. 14:5608–5620.
2024. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Narasimhulu CA and Singla DK: BMP-7
Attenuates sarcopenia and adverse muscle remodeling in diabetic
mice via alleviation of lipids, inflammation, HMGB1, and
pyroptosis. Antioxidants (Basel). 12:3312023. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Galluzzi L, Vitale I, Aaronson SA, Abrams
JM, Adam D, Agostinis P, Alnemri ES, Altucci L, Amelio I, Andrews
DW, et al: Molecular mechanisms of cell death: Recommendations of
the Nomenclature committee on cell death 2018. Cell Death Differ.
25:486–541. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Shoji S and Mentz RJ: Beyond quadruple
therapy: The potential roles for ivabradine, vericiguat, and
omecamtiv mecarbil in the therapeutic armamentarium. Heart Fail
Rev. 29:949–955. 2024. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Bentivegna E, Galastri S, Onan D and
Martelletti P: Unmet needs in the acute treatment of migraine. Adv
Ther. 41:1–13. 2024. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Perryman R, Chau TW, De-Felice J, O'Neill
K and Syed N: Distinct capabilities in NAD metabolism mediate
resistance to NAMPT inhibition in glioblastoma. Cancers (Basel).
16:20542024. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Abdellatif M, Sedej S and Kroemer G:
NAD+ metabolism in cardiac health, aging, and disease.
Circulation. 144:1795–1817. 2021. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Chu X and Raju RP: Regulation of NAD(+)
metabolism in aging and disease. Metabolism. 126:1549232022.
View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Lin Q, Zuo W, Liu Y, Wu K and Liu Q:
NAD(+) and cardiovascular diseases. Clin Chim Acta. 515:104–110.
2021. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Yoshino M, Yoshino J, Kayser BD, Patti GJ,
Franczyk MP, Mills KF, Sindelar M, Pietka T, Patterson BW, Imai SI
and Klein S: Nicotinamide mononucleotide increases muscle insulin
sensitivity in prediabetic women. Science. 372:1224–1229. 2021.
View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Cheng L, Deepak RNVK, Wang G, Meng Z, Tao
L, Xie M, Chi W, Zhang Y, Yang M, Liao Y, et al: Hepatic
mitochondrial NAD + transporter SLC25A47 activates AMPKα mediating
lipid metabolism and tumorigenesis. Hepatology. 78:1828–1842. 2023.
View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Lopaschuk GD, Karwi QG, Tian R, Wende AR
and Abel ED: Cardiac energy metabolism in heart failure. Circ Res.
128:1487–1513. 2021. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Doan KV, Luongo TS, Ts'olo TT, Lee WD,
Frederick DW, Mukherjee S, Adzika GK, Perry CE, Gaspar RB, Walker
N, et al: Cardiac NAD+ depletion in mice promotes
hypertrophic cardiomyopathy and arrhythmias prior to impaired
bioenergetics. Nat Cardiovasc Res. 3:1236–1248. 2024. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Qiu Y, Xu S, Chen X, Wu X, Zhou Z, Zhang
J, Tu Q, Dong B, Liu Z, He J, et al: NAD(+) exhaustion by CD38
upregulation contributes to blood pressure elevation and vascular
damage in hypertension. Signal Transduct Target Ther. 8:3532023.
View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Li J, Zhang C, Hu Y, Peng J, Feng Q and Hu
X: Nicotinamide enhances Treg differentiation by promoting Foxp3
acetylation in immune thrombocytopenia. Br J Haematol.
205:2432–2441. 2024. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Pei Z, Wang F, Wang K and Wang L:
Nicotinamide adenine dinucleotide in the development and treatment
of cardiac remodeling and aging. Mini Rev Med Chem. 22:2310–2317.
2022. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Fritzen AM, Lundsgaard AM and Kiens B:
Tuning fatty acid oxidation in skeletal muscle with dietary fat and
exercise. Nat Rev Endocrinol. 16:683–696. 2020. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Qi XM, Qiao YB, Zhang YL, Wang AC, Ren JH,
Wei HZ and Li QS: PGC-1α/NRF1-dependent cardiac mitochondrial
biogenesis: A druggable pathway of calycosin against triptolide
cardiotoxicity. Food Chem Toxicol. 171:1135132023. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Zhang H, Wang Y, Wu K, Liu R, Wang H, Yao
Y, Kvietys P and Rui T: miR-141 impairs mitochondrial function in
cardiomyocytes subjected to hypoxia/reoxygenation by targeting
Sirt1 and MFN2. Exp Ther Med. 24:7632022. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Ji LL and Yeo D: Maintenance of NAD+
homeostasis in skeletal muscle during aging and exercise. Cells.
11:7102022. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
National Research Council Committee for
the Update of the Guide for the C. A. Use of Laboratory. The
National Academies Collection, . Reports funded by National
Institutes of Health, in Guide for the Care and Use of Laboratory
Animals. National Academies Press; Washington, DC: 2011
|
|
24
|
Nishida Y, Nawaz A, Kado T, Takikawa A,
Igarashi Y, Onogi Y, Wada T, Sasaoka T, Yamamoto S, Sasahara M, et
al: Astaxanthin stimulates mitochondrial biogenesis in insulin
resistant muscle via activation of AMPK pathway. J Cachexia
Sarcopenia Muscle. 11:241–258. 2020. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Brault V, Duchon A, Romestaing C, Sahun I,
Pothion S, Karout M, Borel C, Dembele D, Bizot JC, Messaddeq N, et
al: Opposite phenotypes of muscle strength and locomotor function
in mouse models of partial trisomy and monosomy 21 for the proximal
Hspa13-App region. PLoS Genet. 11:e10050622015. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Wang L, Lavier J, Hua W, Wang Y, Gong L,
Wei H, Wang J, Pellegrin M, Millet GP and Zhang Y: High-Intensity
interval training and moderate-intensity continuous training
attenuate oxidative damage and promote myokine response in the
skeletal muscle of ApoE KO mice on high-fat diet. Antioxidants
(Basel). 10:9922021. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Pei Z, Li Y, Yao W, Sun F and Pan X:
NAD+ Protects against hyperlipidemia-induced kidney
injury in apolipoprotein E-deficient mice. Cur Pharm Biotechnol.
25:488–498. 2024. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Aravani D, Kassi E, Chatzigeorgiou A and
Vakrou S: Cardiometabolic syndrome: An update on available mouse
models. Thromb Haemost. 121:703–715. 2021. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Poledne R and Jurčíková-Novotná L:
Experimental models of hyperlipoproteinemia and atherosclerosis.
Physiol Res. 66 (Suppl 1):S69–S75. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Park Y, Jang I, Park HY, Kim J and Lim K:
Hypoxic exposure can improve blood glycemic control in high-fat
diet-induced obese mice. Phys Act Nutr. 24:19–23. 2020. View Article : Google Scholar
|
|
31
|
Zhao Y, Qu H, Wang Y, Xiao W, Zhang Y and
Shi D: Small rodent models of atherosclerosis. Biomed Pharmacother.
129:1104262020. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Zhao Y, Zhang J, Zheng Y, Zhang Y, Zhang
XJ, Wang H, Du Y, Guan J, Wang X and Fu J: NAD+ improves
cognitive function and reduces neuroinflammation by ameliorating
mitochondrial damage and decreasing ROS production in chronic
cerebral hypoperfusion models through Sirt1/PGC-1α pathway. J
Neuroinflammation. 18:2072021. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Guo C, Huang Q, Wang Y, Yao Y, Li J, Chen
J, Wu M, Zhang Z, Mingyao E, Qi H, et al: Therapeutic application
of natural products: NAD+ metabolism as potential
target. Phytomedicine. 114:1547682023. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Trueblood NA, Ramasamy R, Wang LF and
Schaefer S: Niacin protects the isolated heart from
ischemia-reperfusion injury. Am J Physiol Heart Circ Physiol.
279:H764–H771. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Perry CE, Halawani SM, Mukherjee S, Ngaba
LV, Lieu M, Lee WD, Davis JG, Adzika GK, Bebenek AN, Bazianos DD,
et al: NAD+ precursors prolong survival and improve cardiac
phenotypes in a mouse model of Friedreich's Ataxia. JCI Insight.
9:e1771522024.PubMed/NCBI
|
|
36
|
Chong MC, Silva A, James PF, Wu SSX and
Howitt J: Exercise increases the release of NAMPT in extracellular
vesicles and alters NAD+ activity in recipient cells.
Aging Cell. 21:e136472022. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Morales-Alamo D and Calbet JAL: AMPK
signaling in skeletal muscle during exercise: Role of reactive
oxygen and nitrogen species. Free Radic Biol Med. 98:68–77. 2016.
View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Glancy B, Kane DA, Kavazis AN, Goodwin ML,
Willis WT and Gladden LB: Mitochondrial lactate metabolism: History
and implications for exercise and disease. J Physiol. 599:863–888.
2021. View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Agorrody G, Peclat TR, Peluso G, Gonano
LA, Santos L, van Schooten W, Chini CCS, Escande C, Chini EN and
Contreras P: Benefits in cardiac function by CD38 suppression:
Improvement in NAD+ levels, exercise capacity, heart
rate variability and protection against catecholamine-induced
ventricular arrhythmias. J Mol Cell Cardiol. 166:11–22. 2022.
View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Cabrera ME, Zhou L, Stanley WC and Saidel
GM: Regulation of cardiac energetics: role of redox state and
cellular compartmentation during ischemia. Ann N Y Acad Sci.
1047:259–270. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Chen Y, Zhang H, Ji S, Jia P, Chen Y, Li Y
and Wang T: Resveratrol and its derivative pterostilbene attenuate
oxidative stress-induced intestinal injury by improving
mitochondrial redox homeostasis and function via SIRT1 signaling.
Free Radic Biol Med. 177:1–14. 2021. View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Hu L, Guo Y, Song L, Wen H, Sun N, Wang Y,
Qi B, Liang Q, Geng J, Liu X, et al: Nicotinamide riboside promotes
Mfn2-mediated mitochondrial fusion in diabetic hearts through the
SIRT1-PGC1α-PPARα pathway. Free Radic Biol Med. 183:75–88. 2022.
View Article : Google Scholar : PubMed/NCBI
|
|
43
|
Wu YC, Yan Q, Yue SQ, Pan LX, Yang DS, Tao
LS, Wei ZY, Rong F, Qian C, Han MQ, et al: NUP85 alleviates lipid
metabolism and inflammation by regulating PI3K/AKT signaling
pathway in nonalcoholic fatty liver disease. Int J Biol Sci.
20:2219–2235. 2024. View Article : Google Scholar : PubMed/NCBI
|
|
44
|
Yu H, Gan D, Luo Z, Yang Q, An D, Zhang H,
Hu Y, Ma Z, Zeng Q, Xu Z and Ren D: α-Ketoglutarate improves
cardiac insufficiency through NAD(+)-SIRT1 signaling-mediated
mitophagy and ferroptosis in pressure overload-induced mice. Mol
Med. 30:152024. View Article : Google Scholar : PubMed/NCBI
|
|
45
|
Ma Y, Kuang Y, Bo W, Liang Q, Zhu W, Cai M
and Tian Z: Exercise training alleviates cardiac fibrosis through
increasing fibroblast growth factor 21 and regulating
TGF-β1-Smad2/3-MMP2/9 signaling in mice with myocardial infarction.
Int J Mol Sci. 22:123412021. View Article : Google Scholar : PubMed/NCBI
|
|
46
|
Walzik D, Joisten N, Schenk A, Trebing S,
Schaaf K, Metcalfe AJ, Spiliopoulou P, Hiefner J, McCann A, Watzl
C, et al: Acute exercise boosts NAD(+) metabolism of human
peripheral blood mononuclear cells. Brain Behav Immun.
123:1011–1023. 2024. View Article : Google Scholar : PubMed/NCBI
|
|
47
|
Yagi M, Toshima T, Amamoto R, Do Y, Hirai
H, Setoyama D, Kang D and Uchiumi T: Mitochondrial translation
deficiency impairs NAD(+) -mediated lysosomal acidification. EMBO
J. 40:e1052682021. View Article : Google Scholar : PubMed/NCBI
|
|
48
|
Li J, Wang T, Liu P, Yang F, Wang X, Zheng
W and Sun W: Hesperetin ameliorates hepatic oxidative stress and
inflammation via the PI3K/AKT-Nrf2-ARE pathway in oleic
acid-induced HepG2 cells and a rat model of high-fat diet-induced
NAFLD. Food Funct. 12:3898–3918. 2021. View Article : Google Scholar : PubMed/NCBI
|
|
49
|
Savova MS, Mihaylova LV, Tews D, Wabitsch
M and Georgiev M: Targeting PI3K/AKT signaling pathway in obesity.
Biomed Pharmacother. 159:1142442023. View Article : Google Scholar : PubMed/NCBI
|
|
50
|
Magaye RR, Savira F, Hua Y, Xiong X, Huang
L, Reid C, Flynn BL, Kaye D, Liew D and Wang BH: Attenuating
PI3K/Akt- mTOR pathway reduces dihydrosphingosine 1 phosphate
mediated collagen synthesis and hypertrophy in primary cardiac
cells. Int J Biochem Cell Biol. 134:1059522021. View Article : Google Scholar : PubMed/NCBI
|
|
51
|
Wawruszak A, Luszczki J, Bartuzi D,
Kalafut J, Okon E, Czerwonka A and Stepulak A: Selisistat, a SIRT1
inhibitor, enhances paclitaxel activity in luminal and
triple-negative breast cancer: In silico, in vitro, and in vivo
studies. J Enzyme Inhib Med Chem. 40:24585542025. View Article : Google Scholar : PubMed/NCBI
|
