|
1
|
Khanam A and Kottilil S: Abnormal innate
immunity in acute-on-chronic liver failure: immunotargets for
therapeutics. Front Immunol. 11:20132020. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Larsen FS and Saliba F: Liver support
systems and liver transplantation in acute liver failure. Liver
Int. 45:e156332025. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Pollok JM, Tinguely P, Berenguer M,
Niemann CU, Raptis DA and Spiro M; ERAS4OLT.org collaborative, :
Enhanced recovery for liver transplantation: Recommendations from
the 2022 international liver transplantation society consensus
conference. Lancet Gastroenterol Hepatol. 8:81–94. 2023. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Jaeschke H and Ramachandran A: Central
mechanisms of acetaminophen hepatotoxicity: Mitochondrial
dysfunction by protein adducts and oxidant stress. Drug Metab
Dispos. 52:712–721. 2024. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Du K, Farhood A and Jaeschke H:
Mitochondria-targeted antioxidant Mito-Tempo protects against
acetaminophen hepatotoxicity. Arch Toxicol. 91:761–773. 2017.
View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Du K, Ramachandran A, McGill MR, Mansouri
A, Asselah T, Farhood A, Woolbright BL, Ding WX and Jaeschke H:
Induction of mitochondrial biogenesis protects against
acetaminophen hepatotoxicity. Food Chem Toxicol. 108:339–350. 2017.
View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Li YF, Xie ZF, Song Q and Li JY:
Mitochondria homeostasis: Biology and involvement in hepatic
steatosis to NASH. Acta Pharmacol Sin. 43:1141–1155. 2022.
View Article : Google Scholar : PubMed/NCBI
|
|
8
|
LeFort KR, Rungratanawanich W and Song BJ:
Contributing roles of mitochondrial dysfunction and hepatocyte
apoptosis in liver diseases through oxidative stress,
post-translational modifications, inflammation, and intestinal
barrier dysfunction. Cell Mol Life Sci. 81:342024. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Ding Q, Qi Y and Tsang SY: Mitochondrial
biogenesis, mitochondrial dynamics, and mitophagy in the maturation
of cardiomyocytes. Cells. 10:24632021. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Tang C, Cai J, Yin XM, Weinberg JM,
Venkatachalam MA and Dong Z: Mitochondrial quality control in
kidney injury and repair. Nat Rev Nephrol. 17:299–318. 2021.
View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Liao X, Wang Y, Zhang Z, Qu X and Zhou G:
Bidirectional regulation of NLRP3 inflammasome and mitochondrial
quality control in sepsis: Mechanisms and therapeutic implications.
Mediators Inflamm. 2026:31686692026. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Liu BH, Xu CZ, Liu Y, Lu ZL, Fu TL, Li GR,
Deng Y, Luo GQ, Ding S, Li N and Geng Q: Mitochondrial quality
control in human health and disease. Mil Med Res.
11:322024.PubMed/NCBI
|
|
13
|
Ma X, McKeen T, Zhang J and Ding WX: Role
and mechanisms of mitophagy in liver diseases. Cells. 9:8372020.
View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Li W, Gui Y, Guo C, Huang Y, Liu Y, Yu X,
Zhang H, Wang J, Liu R, Mahaman YAR, et al: Molecular mechanisms of
mitochondrial quality control. Transl Neurodegener. 14:452025.
View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Wu Y, Luo H, Pan Z, Chen W and Bi L:
Bidirectional crosstalk between ER stress and lipid metabolism:
From proteostasis to tumor adaptation. Cell Death Discov.
12:372025. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Romanelli S and Trempe JF: Stressful
situations: Molecular insights on mitochondrial quality control
pathways. J Biol Chem. 301:1104832025. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Xu X, Pang Y and Fan X: Mitochondria in
oxidative stress, inflammation and aging: From mechanisms to
therapeutic advances. Signal Transduct Target Ther. 10:1902025.
View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Shi J, Yu Y, Yuan H, Li Y and Xue Y:
Mitochondrial dysfunction in AMI: Mechanisms and therapeutic
perspectives. J Transl Med. 23:4182025. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Chatzinikita E, Maridaki M, Palikaras K,
Koutsilieris M and Philippou A: The role of mitophagy in skeletal
muscle damage and regeneration. Cells. 12:7162023. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Liu C, He W and Zhang J: Exercise
regulates mitophagy to alleviate parkinsonian neurodegeneration.
Front Aging Neurosci. 17:16784602025. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Iorio R, Celenza G and Petricca S:
Mitophagy: Molecular mechanisms, new concepts on parkin activation
and the emerging role of AMPK/ULK1 axis. Cells. 11:302021.
View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Vizziello M, Borellini L, Franco G and
Ardolino G: Disruption of mitochondrial homeostasis: The role of
PINK1 in Parkinson's disease. Cells. 10:30222021. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Marinković M and Novak I: A brief overview
of BNIP3L/NIX receptor-mediated mitophagy. FEBS Open Bio.
11:3230–3236. 2021. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Li Y, Zheng W, Lu Y, Zheng Y, Pan L, Wu X,
Yuan Y, Shen Z, Ma S, Zhang X, et al: BNIP3L/NIX-mediated
mitophagy: Molecular mechanisms and implications for human disease.
Cell Death Dis. 13:142021. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Tian S, Zhang Y, Liu C, Zhang H, Lu Q,
Zhao Y and Fan H: Double-edged mitophagy: Balancing inflammation
and resolution in lung disease. Clin Sci (Lond). 139:1047–1072.
2025. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Li A, Gao M, Liu B, Qin Y, Chen L, Liu H,
Wu H and Gong G: Mitochondrial autophagy: Molecular mechanisms and
implications for cardiovascular disease. Cell Death Dis.
13:4442022. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Markaki M, Tsagkari D and Tavernarakis N:
Mitophagy mechanisms in neuronal physiology and pathology during
ageing. Biophys Rev. 13:955–965. 2021. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Wang H, Luo W, Chen H, Cai Z and Xu G:
Mitochondrial dynamics and mitochondrial autophagy: Molecular
structure, orchestrating mechanism and related disorders.
Mitochondrion. 75:1018472024. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Zhang H, Yan J, Xie D, Zhu X, Nie G, Zhang
H and Li X: Selenium restored mitophagic flux to alleviate
cadmium-induced hepatotoxicity by inhibiting excessive
GPER1-mediated mitophagy activation. J Hazard Mater.
475:1348552024. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Wang L, Zhou X and Lu T: Role of
mitochondria in physiological activities, diseases, and therapy.
Mol Biomed. 6:422025. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Prasun P, Ginevic I and Oishi K:
Mitochondrial dysfunction in nonalcoholic fatty liver disease and
alcohol related liver disease. Transl Gastroenterol Hepatol.
6:42021. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Abu Shelbayeh O, Arroum T, Morris S and
Busch KB: PGC-1α is a master regulator of mitochondrial lifecycle
and ROS stress response. Antioxidants (Basel). 12:10752023.
View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Gureev AP, Shaforostova EA and Popov VN:
Regulation of mitochondrial biogenesis as a way for active
longevity: Interaction between the Nrf2 and PGC-1α signaling
pathways. Front Genet. 10:4352019. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Ma L, Wang R, Wang H, Zhang Y and Zhao Z:
Long-term caloric restriction activates the myocardial
SIRT1/AMPK/PGC-1α pathway in C57BL/6J male mice. Food Nutr Res.
64:10.29219/fnr.v64.3668. 2020. View Article : Google Scholar
|
|
35
|
Liu L, Li Y, Chen G and Chen Q: Crosstalk
between mitochondrial biogenesis and mitophagy to maintain
mitochondrial homeostasis. J Biomed Sci. 30:862023. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Hyatt JPK, Lu EJ and McCall GE: Temporal
expression of mitochondrial life cycle markers during acute and
chronic overload of rat plantaris muscles. Front Physiol.
15:14202762024. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Deretic V and Kroemer G: Autophagy in
metabolism and quality control: Opposing, complementary or
interlinked functions? Autophagy. 18:283–292. 2022. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Kozhukhar N and Alexeyev MF: Limited
predictive value of TFAM in mitochondrial biogenesis.
Mitochondrion. 49:156–165. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Popov LD: Mitochondrial biogenesis: An
update. J Cell Mol Med. 24:4892–4899. 2020. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Chen W, Zhao H and Li Y: Mitochondrial
dynamics in health and disease: Mechanisms and potential targets.
Signal Transduct Target Ther. 8:3332023. View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Furukawa K, Maruyama T, Sakai Y, Yamashita
SI, Inoue K, Fukuda T, Noda NN and Kanki T: Mitochondrial fission
during mitophagy requires both inner and outer mitofissins. EMBO
Rep. 27:853–872. 2026. View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Zanfardino P, Amati A, Perrone M and
Petruzzella V: The balance of MFN2 and OPA1 in mitochondrial
dynamics, cellular homeostasis, and disease. Biomolecules.
15:4332025. View Article : Google Scholar : PubMed/NCBI
|
|
43
|
Chen P, Yao L, Yuan M, Wang Z, Zhang Q,
Jiang Y and Li L: Mitochondrial dysfunction: A promising
therapeutic target for liver diseases. Genes Dis. 11:1011152023.
View Article : Google Scholar : PubMed/NCBI
|
|
44
|
Zong Y, Li H, Liao P, Chen L, Pan Y, Zheng
Y, Zhang C, Liu D, Zheng M and Gao J: Mitochondrial dysfunction:
Mechanisms and advances in therapy. Signal Transduct Target Ther.
9:1242024. View Article : Google Scholar : PubMed/NCBI
|
|
45
|
Ye L, Fu X and Li Q: Mitochondrial quality
control in health and disease. MedComm (2020). 6:e703192025.
View Article : Google Scholar : PubMed/NCBI
|
|
46
|
Liu S, Wang L, Zhu L, Zhao T, Han P, Yan
F, Wang X, Li C, Wang Z and Yang BF: Mechanism and regulation of
mitophagy in liver diseases: A review. Front Cell Dev Biol.
13:16149402025. View Article : Google Scholar : PubMed/NCBI
|
|
47
|
Ramachandran A, Umbaugh DS and Jaeschke H:
Mitochondrial dynamics in drug-induced liver injury. Livers.
1:102–115. 2021. View Article : Google Scholar : PubMed/NCBI
|
|
48
|
Rahman FA and Quadrilatero J:
Mitochondrial network remodeling: An important feature of
myogenesis and skeletal muscle regeneration. Cell Mol Life Sci.
78:4653–4675. 2021. View Article : Google Scholar : PubMed/NCBI
|
|
49
|
Chen J, Liu B, Yao X, Yang X, Sun J, Yi J,
Xue F, Zhang J, Shen Y, Chen B and Sun H: AMPK/SIRT1/PGC-1α
signaling pathway: Molecular mechanisms and targeted strategies
from energy homeostasis regulation to disease therapy. CNS Neurosci
Ther. 31:e706572025. View Article : Google Scholar : PubMed/NCBI
|
|
50
|
Saso L, Ates I, Tunc R, Yilmaz B,
Gallorini M, Carradori S and Suzen S: Modulation of Nrf2 and
mitochondrial function: Pharmacological implications.
Pharmaceuticals (Basel). 18:16982025. View Article : Google Scholar : PubMed/NCBI
|
|
51
|
Kim KH and Lee CB: Socialized
mitochondria: Mitonuclear crosstalk in stress. Exp Mol Med.
56:1033–1042. 2024. View Article : Google Scholar : PubMed/NCBI
|
|
52
|
Li J, Liu W, Zhang J and Sun C: The role
of mitochondrial quality control in liver diseases: Dawn of a
therapeutic era. Int J Biol Sci. 21:1767–1783. 2025. View Article : Google Scholar : PubMed/NCBI
|
|
53
|
Fei M, Xu Y, Jin P, Wang Y and Zhou M:
Mitochondrial dysfunction in sepsis-induced liver injury: From
pathophysiology to preclinical therapeutic targets. J Transl Med.
23:13392025. View Article : Google Scholar : PubMed/NCBI
|
|
54
|
Li X, Tang J and Mao Y: Incidence and risk
factors of drug-induced liver injury. Liver Int. 42:1999–2014.
2022. View Article : Google Scholar : PubMed/NCBI
|
|
55
|
Ramachandran A, Visschers RGJ, Duan L,
Akakpo JY and Jaeschke H: Mitochondrial dysfunction as a mechanism
of drug-induced hepatotoxicity: Current understanding and future
perspectives. J Clin Transl Res. 4:75–100. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
56
|
Allard J, Bucher S, Massart J, Ferron PJ,
Le Guillou D, Loyant R, Daniel Y, Launay Y, Buron N, Begriche K, et
al: Drug-induced hepatic steatosis in absence of severe
mitochondrial dysfunction in HepaRG cells: Proof of multiple
mechanism-based toxicity. Cell Biol Toxicol. 37:151–175. 2021.
View Article : Google Scholar : PubMed/NCBI
|
|
57
|
Zhou Q, Cen P, Chen Z and Jin J: Roles of
the Keap1/Nrf2 pathway and mitophagy in liver diseases. J Zhejiang
Univ Sci B. 26:972–994. 2025. View Article : Google Scholar : PubMed/NCBI
|
|
58
|
Jiang Z, Yang X, Han Y, Li J, Hu C, Liu C
and Xiao W: Sarmentosin promotes USP17 and regulates Nrf2-mediated
mitophagy and cellular oxidative stress to alleviate APAP-induced
acute liver failure. Phytomedicine. 104:1543372022. View Article : Google Scholar : PubMed/NCBI
|
|
59
|
Hionides-Gutierrez A,
Goikoetxea-Usandizaga N, Sanz-Garcia C, Martinez-Chantar ML and
Cubero FJ: Novel emerging mechanisms in acetaminophen (APAP)
hepatotoxicity. Liver Int. 45:e161672025. View Article : Google Scholar : PubMed/NCBI
|
|
60
|
Liu D, Zhang R, Zha L, Yao L, Han Y, Zhang
X, Chen Y, Zhan M, Du J and Chen L: Nrf2-activated mitophagy and
ferroptosis suppression synergistically mediate tangeretin's
protection against hepatic ischemia-reperfusion injury.
Phytomedicine. 145:1570342025. View Article : Google Scholar : PubMed/NCBI
|
|
61
|
Li X, Chen W, Jia Z, Xiao Y, Shi A and Ma
X: Mitochondrial dysfunction as a pathogenesis and therapeutic
strategy for metabolic-dysfunction-associated steatotic liver
disease. Int J Mol Sci. 26:42562025. View Article : Google Scholar : PubMed/NCBI
|
|
62
|
Wang S, Long H, Hou L, Feng B, Ma Z, Wu Y,
Zeng Y, Cai J, Zhang DW and Zhao G: The mitophagy pathway and its
implications in human diseases. Signal Transduct Target Ther.
8:3042023. View Article : Google Scholar : PubMed/NCBI
|
|
63
|
de Oliveira THC and Gonçalves GKN: Liver
ischemia reperfusion injury: Mechanisms, cellular pathways, and
therapeutic approaches. Int Immunopharmacol. 150:1142992025.
View Article : Google Scholar : PubMed/NCBI
|
|
64
|
Wang J, Fu W, Lu N, Guo Z, Bing OS, Shi H,
Zhou H, Chang X and Meng M: Hepatic ischemia-reperfusion and
mitochondrial quality control: Potential therapeutic targets. Int
Immunopharmacol. 163:1152672025. View Article : Google Scholar : PubMed/NCBI
|
|
65
|
Machado IF, Palmeira CM and Rolo AP:
Preservation of mitochondrial health in liver ischemia/reperfusion
injury. Biomedicines. 11:9482023. View Article : Google Scholar : PubMed/NCBI
|
|
66
|
Zhou S, Rao Z, Xia Y, Wang Q, Liu Z, Wang
P, Cheng F and Zhou H: CCAAT/enhancer-binding protein homologous
protein promotes ROS-mediated liver ischemia and reperfusion injury
by inhibiting mitophagy in hepatocytes. Transplantation.
107:129–139. 2023. View Article : Google Scholar : PubMed/NCBI
|
|
67
|
Dusabimana T, Kim SR, Kim HJ, Park SW and
Kim H: Nobiletin ameliorates hepatic ischemia and reperfusion
injury through the activation of SIRT-1/FOXO3a-mediated autophagy
and mitochondrial biogenesis. Exp Mol Med. 51:1–16. 2019.
View Article : Google Scholar : PubMed/NCBI
|
|
68
|
Cheng Y and Zheng X: Characteristics and
mechanisms of liver injury caused by emerging infectious diseases.
Front Immunol. 16:16475172025. View Article : Google Scholar : PubMed/NCBI
|
|
69
|
Perez SE, Gooz M and Maldonado EN:
Mitochondrial dysfunction and metabolic disturbances induced by
viral infections. Cells. 13:17892024. View Article : Google Scholar : PubMed/NCBI
|
|
70
|
Yang Y, Shi R, Soomro MH, Hu F, Du F and
She R: Hepatitis E virus induces hepatocyte apoptosis via
mitochondrial pathway in Mongolian gerbils. Front Microbiol.
9:4602018. View Article : Google Scholar : PubMed/NCBI
|
|
71
|
Chen S, Zhu H and Jounaidi Y:
Comprehensive snapshots of natural killer cells functions,
signaling, molecular mechanisms and clinical utilization. Signal
Transduct Target Ther. 9:3022024. View Article : Google Scholar : PubMed/NCBI
|
|
72
|
Qu C, Zhang S, Wang W, Li M, Wang Y, van
der Heijde-Mulder M, Shokrollahi E, Hakim MS, Raat NJH,
Peppelenbosch MP and Pan Q: Mitochondrial electron transport chain
complex III sustains hepatitis E virus replication and represents
an antiviral target. FASEB J. 33:1008–1019. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
73
|
Xu L, Xu Y, Zhang F, Xu P and Wang L:
Immunological pathways in viral hepatitis-induced hepato-cellular
carcinoma. Zhejiang Da Xue Xue Bao Yi Xue Ban. 53:64–72. 2024.(In
English, Chinese). PubMed/NCBI
|
|
74
|
Duan X, Liu R, Lan W and Liu S: The
essential role of mitochondrial dynamics in viral infections. Int J
Mol Sci. 26:19552025. View Article : Google Scholar : PubMed/NCBI
|
|
75
|
Fu C, Cao N, Liu W, Zhang Z, Yang Z, Zhu W
and Fan S: Crosstalk between mitophagy and innate immunity in viral
infection. Front Microbiol. 13:10640452022. View Article : Google Scholar : PubMed/NCBI
|
|
76
|
Tian X, Yuan M, Li L, Chen D, Liu B, Zou
X, He M and Wu Z: Enterovirus 71 induces mitophagy via PINK1/Parkin
signaling pathway to promote viral replication. FASEB J.
39:e706592025. View Article : Google Scholar : PubMed/NCBI
|
|
77
|
Sorouri M, Chang T and Hancks DC:
Mitochondria and viral infection: Advances and emerging
battlefronts. mBio. 13:e02096212022. View Article : Google Scholar : PubMed/NCBI
|
|
78
|
Cao L, Li Y, Smirnov A, Voshtani R, Wang
T, Shao C, Candi E, Melino G, Shi Y and Fang J: PGC-1α: Key
regulator of mitochondrial biogenesis and cellular differentiation
in metabolic and regenerative tissues. Cell Biosci. 16:92025.
View Article : Google Scholar : PubMed/NCBI
|
|
79
|
Hu MM and Shu HB: Mitochondrial
DNA-triggered innate immune response: Mechanisms and diseases. Cell
Mol Immunol. 20:1403–1412. 2023. View Article : Google Scholar : PubMed/NCBI
|
|
80
|
Wang Y, Yang R, Cao Y, Li Y, Zhu Y, Zhang
Z, Fleishman JS, Chen J and Ding M: cGAS-STING targeting offers
novel therapeutic opportunities in liver diseases. Drug Des Devel
Ther. 19:5835–5853. 2025. View Article : Google Scholar : PubMed/NCBI
|
|
81
|
Sato H, Hoshi M, Ikeda F, Fujiyuki T,
Yoneda M and Kai C: Downregulation of mitochondrial biogenesis by
virus infection triggers antiviral responses by cyclic GMP-AMP
synthase. PLoS Pathog. 17:e10098412021. View Article : Google Scholar : PubMed/NCBI
|
|
82
|
Kozhukhar N and Alexeyev MF: TFAM's
contributions to mtDNA replication and OXPHOS biogenesis are
genetically separable. Cells. 11:37542022. View Article : Google Scholar : PubMed/NCBI
|
|
83
|
Wang H, Ni HM, Chao X, Ma X, Rodriguez YA,
Chavan H, Wang S, Krishnamurthy P, Dobrowsky R, Xu DX, et al:
Double deletion of PINK1 and Parkin impairs hepatic mitophagy and
exacerbates acetaminophen-induced liver injury in mice. Redox Biol.
22:1011482019. View Article : Google Scholar : PubMed/NCBI
|
|
84
|
Xiang L, Shao Y and Chen Y: Mitochondrial
dysfunction and mitochondrion-targeted therapeutics in liver
diseases. J Drug Target. 29:1080–1093. 2021. View Article : Google Scholar : PubMed/NCBI
|
|
85
|
Hong WL, Huang H, Zeng X and Duan CY:
Targeting mitochondrial quality control: New therapeutic strategies
for major diseases. Mil Med Res. 11:592024.PubMed/NCBI
|
|
86
|
Wang Y, Liu Z, Shu S, Cai J, Tang C and
Dong Z: AMPK/mTOR signaling in autophagy regulation during
cisplatin-induced acute kidney injury. Front Physiol.
11:6197302020. View Article : Google Scholar : PubMed/NCBI
|
|
87
|
Abdel-Zaher AO, Bakr MH, Gad YH and
Abdelhafez AT: Novel mechanistic insights of the potential role of
gasotransmitters and autophagy in the protective effect of
metformin against hepatic ischemia/reperfusion injury in rats.
Naunyn Schmiedebergs Arch Pharmacol. 398:9177–9198. 2025.
View Article : Google Scholar : PubMed/NCBI
|
|
88
|
Zhang Q, Guo J, Shi C, Zhang D, Wang Y,
Wang L and Gong Z: The SIRT2-AMPK axis regulates autophagy induced
by acute liver failure. Sci Rep. 14:162782024. View Article : Google Scholar : PubMed/NCBI
|
|
89
|
Yang M, Wei X, Yi X and Jiang DS:
Mitophagy-related regulated cell death: Molecular mechanisms and
disease implications. Cell Death Dis. 15:5052024. View Article : Google Scholar : PubMed/NCBI
|
|
90
|
Zhang M, Zhang T, Zou R, He K, Huang R,
Feng J, Hu J, Ge T, Fan X, Zhou H and Chen Y: Mitochondrial quality
control as a therapeutic target in cardiovascular disease:
Mechanistic insights and future directions. J Transl Int Med.
13:211–240. 2025. View Article : Google Scholar : PubMed/NCBI
|
|
91
|
Shan S, Liu Z, Wang S, Liu Z, Huang Z,
Yang Y, Zhang C and Song F: Drp1-mediated mitochondrial fission
promotes carbon tetrachloride-induced hepatic fibrogenesis in mice.
Toxicol Res (Camb). 11:486–497. 2022. View Article : Google Scholar : PubMed/NCBI
|
|
92
|
Zhang Q, Liu Z, Huang X, Heng X, Wu J,
Chen Z, Guo X, Fan J and Huang Q: Mdivi-1 alleviates sepsis-induced
liver injury by inhibiting sting signaling activation. Shock.
62:95–102. 2024. View Article : Google Scholar : PubMed/NCBI
|
|
93
|
Mukherjee N, Sheetz J and Shellman YG:
Targeting the BCL2 family: Advances and challenges in BH3
mimetic-based therapies. Int J Mol Sci. 26:98592025. View Article : Google Scholar : PubMed/NCBI
|
|
94
|
Cen X, Chen Y, Xu X, Wu R, He F, Zhao Q,
Sun Q, Yi C, Wu J, Najafov A and Xia H: Pharmacological targeting
of MCL-1 promotes mitophagy and improves disease pathologies in an
Alzheimer's disease mouse model. Nat Commun. 11:57312020.
View Article : Google Scholar : PubMed/NCBI
|
|
95
|
Jin L, Yu B, Liu G, Nie W, Wang J, Chen J,
Xiao L, Xia H, Han F and Yang Y: Mitophagy induced by UMI-77
preserves mitochondrial fitness in renal tubular epithelial cells
and alleviates renal fibrosis. FASEB J. 36:e223422022. View Article : Google Scholar : PubMed/NCBI
|
|
96
|
Abdullah-Al-Shoeb M, Sasaki K, Kikutani S,
Namba N, Ueno K, Kondo Y, Maeda H, Maruyama T, Irie T and Ishitsuka
Y: The late-stage protective effect of mito-TEMPO against
acetaminophen-induced hepatotoxicity in mouse and three-dimensional
cell culture models. Antioxidants (Basel). 9:9652020. View Article : Google Scholar : PubMed/NCBI
|
|
97
|
Wu L, Chen Q, Dong B, Geng H, Wang Y, Han
D, Zhu X, Liu H, Zhang Z, Yang Y, et al: Resveratrol alleviates
lipopolysaccharide-induced liver injury by inducing
SIRT1/P62-mediated mitophagy in gibel carp (Carassius gibelio).
Front Immunol. 14:11771402023. View Article : Google Scholar : PubMed/NCBI
|
|
98
|
Wu H, Wu L, Luo L, Wu YT, Zhang QX, Li HY
and Zhang BF: Quercetin inhibits mitophagy-mediated apoptosis and
inflammatory response by targeting the PPARγ/PGC-1α/NF-κB axis to
improve acute liver failure. Int Immunopharmacol. 143:1134442024.
View Article : Google Scholar : PubMed/NCBI
|
|
99
|
Xie YL, Chu JG, Jian XM, Dong JZ, Wang LP,
Li GX and Yang NB: Curcumin attenuates
lipopolysaccharide/d-galactosamine-induced acute liver injury by
activating Nrf2 nuclear translocation and inhibiting NF-kB
activation. Biomed Pharmacother. 91:70–77. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
100
|
Visalli F, Capobianco M, Cappellani F,
Rapisarda L, Spinello A, Avitabile A, Cannizzaro L, Gagliano C and
Zeppieri M: Mitochondrial health through nicotinamide riboside and
berberine: Shared pathways and therapeutic potential. Int J Mol
Sci. 27:4852026. View Article : Google Scholar : PubMed/NCBI
|
|
101
|
Shi X, Zhang J, Gao J, Guo D, Zhang S,
Chen X and Tang H: Melatonin attenuates liver ischemia-reperfusion
injury via inhibiting the PGAM5-mPTP pathway. PLoS One.
19:e03128532024. View Article : Google Scholar : PubMed/NCBI
|
|
102
|
Mantle D, Hargreaves IP, Domingo JC and
Castro-Marrero J: Mitochondrial dysfunction and coenzyme Q10
supplementation in post-viral fatigue syndrome: An overview. Int J
Mol Sci. 25:5742024. View Article : Google Scholar : PubMed/NCBI
|
|
103
|
Qin X, Jiang M, Zhao Y, Gong J, Su H, Yuan
F, Fang K, Yuan X, Yu X, Dong H and Lu F: Berberine protects
against diabetic kidney disease via promoting PGC-1α-regulated
mitochondrial energy homeostasis. Br J Pharmacol. 177:3646–3661.
2020. View Article : Google Scholar : PubMed/NCBI
|
|
104
|
Koh YC, Lin SJ, Hsu KY, Nagabhushanam K,
Ho CT and Pan MH: Pterostilbene enhances thermogenesis and
mitochondrial biogenesis by activating the SIRT1/PGC-1alpha/SIRT3
pathway to prevent western diet-induced obesity. Mol Nutr Food Res.
67:e23003702023. View Article : Google Scholar : PubMed/NCBI
|
|
105
|
Mukkala AN, David BA, Ailenberg M, Liang
J, Vaswani CM, Karakas D, Goldfarb R, Barbour W, Gasner A, Wu RS,
et al: Mitochondrial transplantation: A novel therapy for liver
ischemia/reperfusion injury. Ann Surg. 281:1032–1047. 2025.
View Article : Google Scholar : PubMed/NCBI
|
|
106
|
Thomas MA, Fahey MJ, Pugliese BR, Irwin
RM, Antonyak MA and Delco ML: Human mesenchymal stromal cells
release functional mitochondria in extracellular vesicles. Front
Bioeng Biotechnol. 10:8701932022. View Article : Google Scholar : PubMed/NCBI
|
|
107
|
Tan YL, Eng SP, Hafez P, Abdul Karim N,
Law JX and Ng MH: Mesenchymal stromal cell mitochondrial transfer
as a cell rescue strategy in regenerative medicine: A review of
evidence in preclinical models. Stem Cells Transl Med. 11:814–827.
2022. View Article : Google Scholar : PubMed/NCBI
|
|
108
|
Li M, Wu L, Si H, Wu Y, Liu Y, Zeng Y and
Shen B: Engineered mitochondria in diseases: Mechanisms,
strategies, and applications. Signal Transduct Target Ther.
10:712025. View Article : Google Scholar : PubMed/NCBI
|
|
109
|
Miao X, Jiang P, Wang Z, Kong W and Feng
L: Mitochondrial transplantation: A novel therapeutic approach for
treating diseases. MedComm (2020). 6:e702532025. View Article : Google Scholar : PubMed/NCBI
|
|
110
|
Li Y, Li XM, Wei LS and Ye JF:
Advancements in mitochondrial-targeted nanotherapeutics: Overcoming
biological obstacles and optimizing drug delivery. Front Immunol.
15:14519892024. View Article : Google Scholar : PubMed/NCBI
|