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Molecular Medicine Reports
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Print ISSN: 1791-2997 Online ISSN: 1791-3004
Journal Cover
January-February 2010 Volume 3 Issue 1

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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January-February 2010 Volume 3 Issue 1

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Article

Keloids: Fundamental principles and prospects (Review)

  • Authors:
    • Matthias Gieringer
    • Katharine Elliott
    • Jan Gosepath
    • Ramin Naim

  • View Affiliations / Copyright

    Affiliations: Klinik für Hals-, Nasen- und Ohrenheilkunde, Kopf- und Halschirurgie, HSK, Dr Horst Schmidt Kliniken GmbH, 65199 Wiesbaden, Germany. mkgieringer@gmail.com
  • Pages: 13-19
    |
    Published online on: January 1, 2010
       https://doi.org/10.3892/mmr_00000212
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Abstract

Wound healing is a very complex process of interactions between different cells, growth factors, blood elements and extracellular matrix. Keloids represent one of the possible complications in the fundamental process of cutaneous wound repair. Despite all efforts, keloids remain a therapeutic challenge since no treatment is as yet considered 100% effective. Growth factors, discovered in the late 1970s, have been shown to influence dermal regeneration. However, the exogenous application of growth factors to chronic wounds has not proven to be effective in healing them. Additionally, genetic analysis has not revealed any single gene that might cause keloids; as such, classic gene therapy is not a feasible option for the treatment of keloids. A new approach is so-called somatic gene therapy. This review provides an overview of the fundamentals of wound healing and of keloids, and presents new possibilities that may improve cutaneous wound repair.

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Copy and paste a formatted citation
Spandidos Publications style
Gieringer M, Elliott K, Gosepath J and Naim R: Keloids: Fundamental principles and prospects (Review) . Mol Med Rep 3: 13-19, 2010.
APA
Gieringer, M., Elliott, K., Gosepath, J., & Naim, R. (2010). Keloids: Fundamental principles and prospects (Review) . Molecular Medicine Reports, 3, 13-19. https://doi.org/10.3892/mmr_00000212
MLA
Gieringer, M., Elliott, K., Gosepath, J., Naim, R."Keloids: Fundamental principles and prospects (Review) ". Molecular Medicine Reports 3.1 (2010): 13-19.
Chicago
Gieringer, M., Elliott, K., Gosepath, J., Naim, R."Keloids: Fundamental principles and prospects (Review) ". Molecular Medicine Reports 3, no. 1 (2010): 13-19. https://doi.org/10.3892/mmr_00000212
Copy and paste a formatted citation
x
Spandidos Publications style
Gieringer M, Elliott K, Gosepath J and Naim R: Keloids: Fundamental principles and prospects (Review) . Mol Med Rep 3: 13-19, 2010.
APA
Gieringer, M., Elliott, K., Gosepath, J., & Naim, R. (2010). Keloids: Fundamental principles and prospects (Review) . Molecular Medicine Reports, 3, 13-19. https://doi.org/10.3892/mmr_00000212
MLA
Gieringer, M., Elliott, K., Gosepath, J., Naim, R."Keloids: Fundamental principles and prospects (Review) ". Molecular Medicine Reports 3.1 (2010): 13-19.
Chicago
Gieringer, M., Elliott, K., Gosepath, J., Naim, R."Keloids: Fundamental principles and prospects (Review) ". Molecular Medicine Reports 3, no. 1 (2010): 13-19. https://doi.org/10.3892/mmr_00000212
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