Gallbladder carcinoma with a large monolocular cystic cancerous component

Hiraki,Masatsugu; Yakushiji,Hiroyuki; Hashiguchi,Kazuyoshi; Harada,Sadami; Kohya,Naohiko; Kai,Keita; Yamaguchi,Kanako; Mori,Daisuke; Irie,Koji; Tokunaga,Osamu; Noshiro,Hirokazu; Miyazaki,Kohji

doi:10.3892/ol.2010.182

November-December 2010 Volume 1 Issue 6

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November-December 2010 Volume 1 Issue 6

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Article

Gallbladder carcinoma with a large monolocular cystic cancerous component

Authors:
- Masatsugu Hiraki
- Hiroyuki Yakushiji
- Kazuyoshi Hashiguchi
- Sadami Harada
- Naohiko Kohya
- Keita Kai
- Kanako Yamaguchi
- Daisuke Mori
- Koji Irie
- Osamu Tokunaga
- Hirokazu Noshiro
- Kohji Miyazaki
View Affiliations / Copyright

Affiliations: Department of Surgery, Saga University Faculty of Medicine, Saga 849-8501, Japan, Department of Surgery, Taku City Hospital, Taku, Saga 846-0031, Japan, Department of Internal Medicine, Taku City Hospital, Taku, Saga 846-0031, Japan, Department of Pathology, Saga Prefectural Hospital Koseikan, Saga 840-8571, Japan, Department of Pathology and Biodefense, Saga University Faculty of Medicine, Saga 849-8501, Japan
Pages: 995-998
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Published online on: September 23, 2010

https://doi.org/10.3892/ol.2010.182
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Abstract

The monolocular cystic formation associated with gallbladder carcinoma is an extremely rare condition. A 79-year-old female suffering from upper abdominal pain and distention was admitted to our hospital. Ultrasonography and computed tomography revealed a monolocular cyst with an irregular wall thickness of 15 cm in diameter concomitant with a solid mass of 8 cm in diameter around the gallbladder bed. During celiotomy, the tumor was found to have a large pale gray cystic component at the fundus of the gallbladder, and disseminated nodules were observed in the peritoneum. We diagnosed the patient with gallbladder carcinoma and performed a simple cholecystectomy that included the tumor without systematic lymphadenectomy. On the cut face of the gallbladder, the lumen was occupied by a solid neoplasm. The cyst included a large amount of serous fluid and protruded continuously from the body of the gallbladder, but it did not communicate with the gallbladder lumen. Although the mechanism responsible for the development of cyst-forming papillary carcinoma of the gallbladder remains unknown, the present case is crucial for understanding the mechanism of cystogenesis in gallbladder carcinoma.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Gallbladder carcinoma with a large monolocular cystic cancerous component

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