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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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February 2013 Volume 5 Issue 2

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Case Report

Solitary plasmacytoma of the skull: Two case reports

  • Authors:
    • Lun Dong
    • Xian Zhang
    • Hengzhu Zhang
    • Ruihong Song
    • Xuewen Gu
    • Liang He

  • View Affiliations / Copyright

    Affiliations: Department of Neurosurgery, Clinical Medical College, Yangzhou University, Yangzhou 225001, Jiangsu, P.R. China, Department of Pathology, Clinical Medical College, Yangzhou University, Yangzhou 225001, Jiangsu, P.R. China
  • Pages: 479-482
    |
    Published online on: November 26, 2012
       https://doi.org/10.3892/ol.2012.1046
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Abstract

Solitary plasmacytoma of the skull is rare and few cases have been reported in the English literature.Plasmacytoma of the skull has a wide spectrum of pathology, including a quite benign, solitary plasmacytoma (SPC), and an extremely malignant, multiple myeloma (MM) at the two ends of the spectrum. The prognosis for solitary plasmacytoma of the skull appears to be good when it can be diagnosed on strict criteria. The clinical features of solitary plasmacytoma of the skull are complex and not easily identified, resulting in a high misdiagnosis rate. A comprehensive examination and analysis which includes radiological examination, immunoglobulin, biochemistry, test for Bence Jones protein in the urine and bone marrow is needed for correct diagnosis. If the skull lesion is isolated, with accompanying marked swelling in the area and tenderness, plasmacytoma must be considered as a possibility for the cause of solitary skull masses. Two cases of solitary plasmacytoma of the skull lesions were retrospectively reviewed, in which a comprehensive examination was used in order to predict the clinical course of solitary plasmacytoma of the skull. The patients received postoperative radiation and/or chemotherapy. Survival following surgery was longer than 2 years for patient 1, and patient 2 is alive at the 18-month follow-up.
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Copy and paste a formatted citation
Spandidos Publications style
Dong L, Zhang X, Zhang H, Song R, Gu X and He L: Solitary plasmacytoma of the skull: Two case reports. Oncol Lett 5: 479-482, 2013.
APA
Dong, L., Zhang, X., Zhang, H., Song, R., Gu, X., & He, L. (2013). Solitary plasmacytoma of the skull: Two case reports. Oncology Letters, 5, 479-482. https://doi.org/10.3892/ol.2012.1046
MLA
Dong, L., Zhang, X., Zhang, H., Song, R., Gu, X., He, L."Solitary plasmacytoma of the skull: Two case reports". Oncology Letters 5.2 (2013): 479-482.
Chicago
Dong, L., Zhang, X., Zhang, H., Song, R., Gu, X., He, L."Solitary plasmacytoma of the skull: Two case reports". Oncology Letters 5, no. 2 (2013): 479-482. https://doi.org/10.3892/ol.2012.1046
Copy and paste a formatted citation
x
Spandidos Publications style
Dong L, Zhang X, Zhang H, Song R, Gu X and He L: Solitary plasmacytoma of the skull: Two case reports. Oncol Lett 5: 479-482, 2013.
APA
Dong, L., Zhang, X., Zhang, H., Song, R., Gu, X., & He, L. (2013). Solitary plasmacytoma of the skull: Two case reports. Oncology Letters, 5, 479-482. https://doi.org/10.3892/ol.2012.1046
MLA
Dong, L., Zhang, X., Zhang, H., Song, R., Gu, X., He, L."Solitary plasmacytoma of the skull: Two case reports". Oncology Letters 5.2 (2013): 479-482.
Chicago
Dong, L., Zhang, X., Zhang, H., Song, R., Gu, X., He, L."Solitary plasmacytoma of the skull: Two case reports". Oncology Letters 5, no. 2 (2013): 479-482. https://doi.org/10.3892/ol.2012.1046
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