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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
February 2013 Volume 5 Issue 2

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Journal Metrics

Impact Factor: 2.1

CiteScore: 3.7

CiteScore Rank: Q3: #233/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Review

Active autophagy in the tumor microenvironment: A novel mechanism for cancer metastasis (Review)

Yinghua Xu, Xiaoping Xia, Hongming Pan
Pages: 411-416
Published online on: 07 November 2012

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Review

Function and mechanism by which interferon regulatory factor‑1 inhibits oncogenesis (Review)

Fei‑Fei Chen, Guan Jiang, Kerui Xu, Jun‑Nian Zheng
Pages: 417-423
Published online on: 28 November 2012

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Review

The evolution in melanoma treatment as a reflection of precision-oriented medicine (Review)

Igal Kushnir, Ofer Merimsky
Pages: 424-426
Published online on: 05 December 2012

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Article

Factors affecting the sensitivity of human-derived esophageal carcinoma cell lines to 5-fluorouracil and cisplatin

Tetsuya Minegaki, Kohji Takara, Ryohei Hamaguchi, Masayuki Tsujimoto, Kohshi Nishiguchi
Pages: 427-434
Published online on: 05 November 2012

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Article

Observational study on the efficacy and safety of erlotinib in patients with non-small cell lung cancer

Takayuki Kaburagi, Hiroaki Satoh, Kenji Hayashihara, Takeshi Endo, Nobuyuki Hizawa, Koichi Kurishima, Yoshihiro Nishimura, Toshio Hashimoto, Hiroyuki Nakamura, Koji  Kishi, Masaharu Inagaki, Takeshi Nawa, Hideo Ichimura, Hiroichi  Ishikawa, Katsunori Kagohashi, Toshihiko  Fukuoka, Yoko Shinohara, Koichi  Kamiyama, Yukio  Sato, Mitsuaki  Sakai, Takeshi Matsumura, Keiko Uchiumi, Kinya Furukawa
Pages: 435-439
Published online on: 27 November 2012

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Article

Synergistic interaction between sorafenib and gemcitabine in EGFR‑TKI‑sensitive and EGFR‑TKI‑resistant human lung cancer cell lines

Jing Li, Yue‑Yin Pan, Ying Zhang
Pages: 440-446
Published online on: 07 November 2012

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Article

Clinical outcomes of giant cell tumor of bone treated with bone cement filling and internal fixation, and oral bisphosphonates

Xiuchun Yu, Ming Xu, Songfeng Xu, Qing Su
Pages: 447-451
Published online on: 20 November 2012

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Article

Investigation of the expression patterns and correlation of DNA methyltransferases and class I histone deacetylases in ovarian cancer tissues

Yifeng Gu, Peifang Yang, Qing Shao, Xia Liu, Sheng Xia, Miaomiao Zhang, Huaxi Xu, Qixiang Shao
Pages: 452-458
Published online on: 03 December 2012

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Case Report

Synchronous solid neuroendocrine breast carcinoma and abdominal lymphoma: A case report and review of the literature

Miguel Alonso-Ruano, Eugeni López-Bonet, Maria   Victoria Huerta‑Anaya, Ester Vila-Camps, Luis Bernadó, Francesc Tuca‑Rodríguez, Pedro Suarez-Pumariega, Javier A. Menendez
Pages: 459-462
Published online on: 23 November 2012

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Article

Effects of different sequences of pulmonary artery and vein ligations during pulmonary lobectomy on blood micrometastasis of non-small cell lung cancer

Ping-Ping Song, Weidi Zhang, Baijiang Zhang, Qi Liu, Jiajun Du
Pages: 463-468
Published online on: 09 November 2012

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Case Report

Epidermoid cyst arising from an intrapancreatic accessory spleen: A case report and review of the literature

Ran Hong, Namkyu Choi, Kyunghoon Sun, Sharon Lim, Yunju Han
Pages: 469-472
Published online on: 04 December 2012

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Article

High expression of FER tyrosine kinase predicts poor prognosis in clear cell renal cell carcinoma

Can Wei, Song Wu, Xianxin Li, Yadong Wang, Rui Ren, Yongqing Lai, Jiongxian Ye
Pages: 473-478
Published online on: 16 November 2012

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Case Report

Solitary plasmacytoma of the skull: Two case reports

Lun Dong, Xian Zhang, Hengzhu Zhang, Ruihong Song, Xuewen Gu, Liang He
Pages: 479-482
Published online on: 26 November 2012

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Article

Analgesic-antitumor peptide induces apoptosis and inhibits the proliferation of SW480 human colon cancer cells

Yu Gu, Shen-Lin Liu, Wen-Zheng Ju, Chang-Yin Li, Peng Cao
Pages: 483-488
Published online on: 27 November 2012

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Article

An engineered three-dimensional gastric tumor culture model for evaluating the antitumor activity of immune cells in vitro

Peiming Sun, Yingxin Xu, Xiaohui Du, Ning Ning, Huiwei Sun, Wentao Liang, Rong Li
Pages: 489-494
Published online on: 09 November 2012

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Case Report

Rapidly evolving asymptomatic eosinophilia in a patient with lung adenocarcinoma causes cognitive disturbance and respiratory insufficiency: Case report

Cheng-Hsiang Lo, Yee-Min Jen, Wen-Chiuan Tsai, Ping-Ying Chung, Woei-Yau Kao
Pages: 495-498
Published online on: 09 November 2012

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Article

Analysis of the expression of the Notch3 receptor protein in adult lung cancer

Min Zhou, Wei-Yun Jin, Zhi-Wen Fan, Rui-Chao Han
Pages: 499-504
Published online on: 19 November 2012

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Article

Astrocyte elevated gene‑1 regulates osteosarcoma cell invasion and chemoresistance via endothelin‑1/endothelin A receptor signaling

Bo Liu, Yi Wu, Dan Peng
Pages: 505-510
Published online on: 03 December 2012

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Article

Evaluating the effect of high-intensity focused ultrasound therapy on liver tumors using multislice CT perfusion

Xinshan Cao, Xingyue Jiang
Pages: 511-514
Published online on: 10 December 2012

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Article

Simultaneous cytomorphological and multiparameter flow cytometric analysis of ALK-positive anaplastic large cell lymphoma in children

Hongqiang Shen, Yongmin Tang, Xiaojun Xu, Hongfeng Tang, Weizhong Gu
Pages: 515-520
Published online on: 19 November 2012

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Article

Function and mode of action of cytohesins in the epidermal growth factor pathway in colorectal cancer cells

Tao Pan, Junfeng Sun, Jun Zhou, Zhixuan Fu, Yiwang Hu, Shu Zheng, Suzhan Zhang
Pages: 521-526
Published online on: 05 December 2012

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Article

Dasatinib inhibits primary melanoma cell proliferation through morphology‑dependent disruption of Src‑ERK signaling

Jianghong Wu, Xin Liao, Bo Yu, Bing Su
Pages: 527-532
Published online on: 10 December 2012

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Article

The expression of phospholipase A2 group X is inversely associated with metastasis in colorectal cancer

Masaya Hiyoshi, Joji Kitayama, Shinsuke Kazama, Yoshitaka  Taketomi, Makoto Murakami, Nelson H. Tsuno, Kumiko  Hongo, Manabu  Kaneko, Eiji Sunami, Toshiaki Watanabe
Pages: 533-538
Published online on: 10 December 2012

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Article

Adrenal lymphangioma removed by a retroperitoneoscopic procedure

Ben Liu, Yanyuan Li, Shuo Wang
Pages: 539-540
Published online on: 04 December 2012

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Case Report

A surgical approach to giant condyloma (Buschke‑Löwenstein tumour) with underlying superficial vulvar carcinoma: A case report

Josko Zekan, Davor Petrovic, Samer El‑Safadi, Maja Banovic, Davor Hulina, Zlatko Hrgovic
Pages: 541-543
Published online on: 14 November 2012

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Article

Identification of MXRA5 as a novel biomarker in colorectal cancer

Guang-Hui Wang, Ling Yao, Hong-Wei Xu, Wen-Tao Tang, Ji‑Hong Fu, Xiao-Fang Hu, Long Cui, Xue-Min Xu
Pages: 544-548
Published online on: 21 November 2012

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Case Report

Pathological and computed tomography findings of lymphoepithelioma‑like gastric carcinoma with epithelioid granulomas: A case report

Shuguang Liu, Long Jin, Xiaoyan Xu, Ni Lin, Bin Lei, Hong Shen
Pages: 549-551
Published online on: 12 December 2012

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Article

Expression of stem cell factor in gastrointestinal stromal tumors: Implications for proliferation and imatinib resistance

Xiao-Wei Hou, Chen-Guang Bai, Xiao-Hong Liu, Cen Qiu, Ling Huang, Jing-Jing Xu, Da-Lie Ma
Pages: 552-558
Published online on: 09 November 2012

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Article

The incidence and prognostic value of HER2 overexpression and cyclin D1 expression in patients with gastric or gastroesophageal junction adenocarcinoma in Israel

Gil Bar-Sela, Dov Hershkovitz, Nissim Haim, Orit Kaidar-Person, Katerina Shulman, Ofer Ben-Izhak
Pages: 559-563
Published online on: 16 November 2012

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Article

High expression of ZEB1 correlates with liver metastasis and poor prognosis in colorectal cancer

Guang-Jun Zhang, Tong Zhou, Hong-Peng Tian, Zuo-Liang Liu, Shu-Sen Xia
Pages: 564-568
Published online on: 14 November 2012

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Article

rs12976445 variant in the pri‑miR‑125a correlates with a lower level of hsa‑miR‑125a and ERBB2 overexpression in breast cancer patients

Tomasz P. Lehmann, Konstanty Korski, Mathew Ibbs, Piotr  Zawierucha, Sylwia Grodecka‑Gazdecka, Paweł P. Jagodziński
Pages: 569-573
Published online on: 22 November 2012

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Article

Expression of C-X-C chemokine receptor types 1/2 in patients with gastric carcinoma: Clinicopathological correlations and significance

Jun Pu Wang, Wan Ming Hu, Kuan Song Wang, Jun Yu, Bai Hua Luo, Chang Wu, Zhi Hong Chen, Geng Qiu Luo, Yu Wu Liu, Qin Lai Liu, Yan Xiao, Hai Yan Zhou, Xiao Jing Yang, Hai Ying Jiang, Jing He Li, Ji Fang Wen
Pages: 574-582
Published online on: 23 November 2012

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Article

p73 expression is associated with cellular chemosensitivity in human non-small cell lung cancer cell lines

Kaishan Liu, Xiaomei Zhuang, Zhuoying Mai
Pages: 583-587
Published online on: 19 November 2012

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Article

Lenalidomide induces apoptosis and alters gene expression in non-small cell lung cancer cells

Karam Kim, Sungkwan An, Hwa Jun Cha, Yeong Min Choi, Sung Jin Choi, In-Sook An, Hong Ghi Lee, Yoo Hong Min, Su-Jae Lee, Seunghee Bae
Pages: 588-592
Published online on: 30 November 2012

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Article

Staging recurrent ovarian cancer with 18FDG PET/CT

Sanja Dragosavac, Sophie Derchain, Nelson M.G. Caserta, Gustavo De Souza
Pages: 593-597
Published online on: 13 December 2012

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Case Report

Cancer of the supernumerary ovary in Mayer‑Rokitansty‑Küster‑Hauser Syndrome: A case report

Hyo Sook Bae, Min Ji Ryu, In Sun Kim, Sun Haeng Kim, Jae Yun Song
Pages: 598-600
Published online on: 12 December 2012

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Article

Pneumocystis jiroveci pneumonia and colonization in patients with advanced lung cancer

Yosuke Togashi, Katsuhiro Masago, Yutaka Ito, Yuichi Sakamori, Chiyuki  Okuda, Akiko Fukuhara, Hiroki Nagai, Young Hak Kim, Michiaki Mishima
Pages: 601-604
Published online on: 29 November 2012

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Article

A new t(9;11;20;22)(q34;p11.2;q11.21;q11) in a Philadelphia-positive chronic myeloid leukemia case

Walid Al-Achkar, Abdulsamad Wafa, Thomas Liehr
Pages: 605-608
Published online on: 21 November 2012

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Article

Effects of cancer-associated fibroblasts on the migration and invasion abilities of SGC-7901 gastric cancer cells

Chengyi Hu, Zhengcai Wang, Lili Zhai, Miling Yang, Lihui  Shan, Cuicui Chai, Ming Liu, Lifeng Wang
Pages: 609-612
Published online on: 09 November 2012

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Article

Pancreatic cyst fluid analysis for differential diagnosis between benign and malignant lesions

Renata Talar‑Wojnarowska, Marek Pazurek, Lukasz Durko, Malgorzata  Degowska, Grazyna Rydzewska, Jacek Smigielski, Adam Janiak, Marek Olakowski, Paweł  Lampe, Piotr Grzelak, Ludomir Stefanczyk, Ewa Malecka‑Panas
Pages: 613-616
Published online on: 12 December 2012

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Article

A novel cytogenetic abnormality t(7;8)(p11.2:q11.2) and a four-way Philadelphia translocation in an imatinib mesylate‑resistant chronic myeloid leukemia patient

Walid Al‑Achkar, Abdulmunim Aljapawe, Suher Almedani, Thomas Liehr, Abdulsamad Wafa
Pages: 617-620
Published online on: 21 November 2012

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Article

Magnetic resonance imaging of the brain in survivors of childhood acute lymphoblastic leukemia

Mohamed Ahmed Badr, Tamer Hasan Hassan, Khaled   Mohamed El‑Gerby, Mohamed El-Sayed Lamey
Pages: 621-626
Published online on: 12 December 2012

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Case Report

Giant extragastrointestinal stromal tumor in the transverse mesocolon concomitant with gastric cancer in an elderly patient: Case report

Dong Xue, Hongqiang Chen, Yuxin Chen
Pages: 627-630
Published online on: 16 November 2012

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Article

Functional epidermal growth factor gene polymorphisms and risk of gastric cancer

Zhen Zhan, Yajun Chen, Juan Wu, Junfeng Zhang, Shujuan Tong, Chunbing Zhang, Yaping Yang
Pages: 631-636
Published online on: 22 November 2012

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Article

Bevacizumab-containing regimens after cetuximab failure in Kras wild-type metastatic colorectal carcinoma

Ka On Lam, Victor Ho Fun Lee, Rico Kin Yin Liu, To Wai Leung, Dora Lai Wan Kwong
Pages: 637-640
Published online on: 26 November 2012

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Article

Chemosensitizing activities of cyclotides from Clitoria ternatea in paclitaxel-resistant lung cancer cells

Zhang Sen, Xiao Kai Zhan, Jin Jing, Zhang Yi, Zhou Wanqi
Pages: 641-644
Published online on: 22 November 2012

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Article

Endogenous PGE2 induces MCP‑1 expression via EP4/p38 MAPK signaling in melanoma

Mingrui Tang, Yuxin Wang, Sihuan Han, Shu Guo, Nan Xu, Jiayan Guo
Pages: 645-650
Published online on: 27 November 2012

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Article

A tailored health surveillance program unveils a case of MALT lymphoma in an HCV-positive health-care worker

Venerando Rapisarda, Andrea Marconi, Saverio Candido, Daria Nicolosi, Mario Salmeri, Pietro Gangemi, Lidia Proietti, Demetrios A. Spandidos, Massimo Bracci, Cettina Fenga, Massimo Libra
Pages: 651-654
Published online on: 15 November 2012

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Article

Anticancer effects of 3,3'-diindolylmethane are associated with G1 arrest and mitochondria-dependent apoptosis in human nasopharyngeal carcinoma cells

Yu Xu, Jin Zhang, Wendan Shi, Yun Liu
Pages: 655-662
Published online on: 05 December 2012

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Article

Mini-array of multiple tumor-associated antigens (TAAs) in the immunodiagnosis of breast cancer

Hua Ye, Changqing Sun, Pengfei Ren, Liping Dai, Bo  Peng, Kaijuan Wang, Wei Qian, Jianying Zhang
Pages: 663-668
Published online on: 05 December 2012

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Article

The glial fibrillary acidic protein promoter directs sodium/iodide symporter gene expression for radioiodine therapy of malignant glioma

Wei Li, Jian Tan, Peng Wang, Ning Li, Fuhai Zhang
Pages: 669-674
Published online on: 03 December 2012

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Article

Inhibition of MCF-7 breast cancer cell-induced platelet aggregation using a combination of antiplatelet drugs

Lian Lian, Wei Li, Zhen-Yu Li, Yi-Xiang Mao, You-Tao Zhang, Yi-Ming Zhao, Kai Chen, Wei-Ming Duan, Min Tao
Pages: 675-680
Published online on: 13 December 2012

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Article

Paraneoplastic cerebellar degeneration associated with ovarian cancer

Alessia Erika Russo, Simona Scalone, Giulia Costanza Leonardi, Aurora Scalisi, Giorgio Giorda, Roberto Sorio
Pages: 681-683
Published online on: 07 November 2012

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Article

Cisplatin for small cell lung cancer: Associated publications in Science Citation Index Expanded

Yuh‑Shan Ho, Kensuke Nakazawa, Shinya Sato, Tomohiro Tamura, Koichi Kurishima, Hiroaki Satoh
Pages: 684-688
Published online on: 15 November 2012

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Article

Comprehensive clinical and pathological analysis of three rare vascular tumor cases

Fu Li, Lixia Ma, Leling Zhang, Libo Zheng, Xin Lv, Jihua Fu
Pages: 689-693
Published online on: 13 November 2012

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Article

Determining the effect of transforming growth factor-β1 on cdk4 and p27 in gastric cancer and cholangiocarcinoma

Sung Ryol Lee, Jae Wook Shin, Hyung Ook Kim, Byung  Ho Son, Chang Hak Yoo, Jun Ho Shin
Pages: 694-698
Published online on: 13 November 2012

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Case Report

Digestive tract hemorrhage due to complications with gastrointestinal stromal tumor treated with sunitinib: A case report

Yan Liu, He-Long Zhang, Ye Zhang, Jia-Zhuan Mei, Hong-Wei Lin, Yan‑Wei  Guo, Rui-Jun Li, Xiang-Rui Meng, Gui-Ju Liu, Min Li, Peng Xiao, Hua Bai
Pages: 699-701
Published online on: 28 November 2012

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Article

In vitro study of low intensity ultrasound combined with different doses of PDT: Effects on C6 glioma cells

Jian-Hua Li, Zhi-Qiang Chen, Zheng Huang, Qi Zhan, Fu‑Bin  Ren, Jing-Ye Liu, Wu Yue, Zhi Wang
Pages: 702-706
Published online on: 04 December 2012

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Article

Retrospective analysis of 264 multiple myeloma patients

Chuanying Geng, Nian Liu, Guangzhong Yang, Aijun Liu, Yun Leng, Huijuan Wang, Lihong Li, Yin Wu, Yanchen Li, Wenming Chen
Pages: 707-713
Published online on: 09 November 2012

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Case Report

Fatal pneumonitis associated with postoperative intensity-modulated radiotherapy in lung cancer: Case report and review

Yan Hu, Jingjing Li, Xiaoyan Su
Pages: 714-716
Published online on: 30 November 2012

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Article

The mTOR inhibitor AZD8055 inhibits proliferation and glycolysis in cervical cancer cells

Shaoru Li, Yan Li, Ruili Hu, Weihua Li, Haifeng Qiu, Honghua Cai, Shijin Wang
Pages: 717-721
Published online on: 04 December 2012

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Article

Baicalein induces apoptosis in esophageal squamous cell carcinoma cells through modulation of the PI3K/Akt pathway

Hong-Bo Zhang, Ping Lu, Qing-Yin Guo, Zhen-Hua Zhang, Xiang-Yu Meng
Pages: 722-728
Published online on: 10 December 2012

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Journal Cover
October-2026 Volume 32 Issue 4

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Journal Metrics

Impact Factor: 2.1

CiteScore: 3.7

CiteScore Rank: Q3: #233/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Efficacy and safety of rituximab in the treatment of primary central nervous system lymphoma: A meta‑analysis and systematic review of 1,388 patients

Lichaoyue Sun, Wenshu Li, Wei Chen, Chunxing Li, Zhao Ren, Qing Xie, Dongxiao Wang
Article Number: 488
Published online on: 02 September 2026

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Review Open Access

Psychological stress and tumor progression: Molecular mechanisms and therapeutic implications (Review)

Yifei Zhang, Yajun Kong, Shuanbao Zhao
Article Number: 487
Published online on: 02 September 2026

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Article Open Access

Development and evaluation of clinical models based on ultrasound, serum CA153 and molecular subtype in predicting the efficacy of neoadjuvant chemotherapy in breast cancer

Ming-Yue Du, Shu-E Zeng
Article Number: 486
Published online on: 02 September 2026

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Article Open Access

Clinical utility of circulating tumor‑derived endothelial cells in lung cancer detection and prognosis prediction

Xiang Li, Jun Yang, Bin Chen, Ziyu Zhang, Jiangman Zhao, Mengxin Zhao, Zhimou Wang
Article Number: 485
Published online on: 02 September 2026

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Article Open Access

Construction of a new predictive model in head and neck squamous cell carcinoma based on the investigation of extracellular matrix‑associated genes

Liangqian Tu, Yiyin Qiu, Handan Zheng, Bixin Fang, Ming Chen
Article Number: 484
Published online on: 02 September 2026

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Review Open Access
Special Issue

Inhibition or induction of gastrointestinal tumors by ferroptosis and intervention by herbal extracts (Review)

Defei Yin, Qinghua Li, Junwei Liang, Xiaoyan Yan, Dajuan Sun
Article Number: 483
Published online on: 02 September 2026

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Expression of Concern Open Access

[Expression of Concern] Demethylation of microRNA-142 induced by demethylation agents plays a suppressive role in osteosarcoma cells

Muliang Ding, Jianzhong Hu, Jiangdong Ni, Zhonghui Zheng, Deye Song, Junjie Wang
Article Number: 482
Published online on: 01 September 2026

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Article Open Access

CCT2 defines a highly cisplatin‑resistant and poor‑prognosis subtype of lung adenocarcinoma

Huafang Mao, Chao Su, Xiaoliang Han, Guoxia Wang
Article Number: 481
Published online on: 28 August 2026

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Expression of Concern Open Access

[Expression of Concern] Simvastatin potentiates doxorubicin activity against MCF‑7 breast cancer cells

Benjaporn Buranrat, Wanwisa Suwannaloet, Jarinyaporn Naowaboot
Article Number: 480
Published online on: 27 August 2026

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Article Open Access

Characterization of ZIC5 expression in esophageal squamous cell carcinoma and its association with patient survival

Bo Yang, Baige Wang, Haiquan Deng, Yong Luo, Shenghao Wu, Huaxin Yin, Hongdian Zhang, Yuncheng Zhang, Zhen Zhang
Article Number: 479
Published online on: 26 August 2026

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Review Open Access

Microbiome‑based diagnostic biomarkers in pancreatic ductal adenocarcinoma: Current evidence and translational challenges (Review)

Huiya Jin, Hui Sun, Jing Yang
Article Number: 478
Published online on: 26 August 2026

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Correction Open Access

[Corrigendum] Long non-coding RNA CCAT2 functions as an oncogene in hepatocellular carcinoma, regulating cellular proliferation, migration and apoptosis

Ning Zhou, Zhongzhou Si, Ting Li, Guangshun Chen, Zhongqiang Zhang, Haizhi Qi
Article Number: 477
Published online on: 26 August 2026

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Article Open Access

Efficacy and safety of ICI‑based triple combination therapy for gene‑negative advanced lung adenocarcinoma

Diwei Mo, Huan Chen, Zhihong Zhu, Jinghua Yu, Xia Yang, Yiyu Lu, Keng Wang, Guifeng Xu, Luwen Lei, Xingxi Pan
Article Number: 476
Published online on: 25 August 2026

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Correction Open Access

[Corrigendum] Angiotensin II type 2 receptor‑interacting protein 3a suppresses proliferation, migration and invasion in tongue squamous cell carcinoma via the extracellular signal‑regulated kinase‑Snai2 pathway

Tingting Zhao, Qianting He, Zhonghua Liu, Xueqiang Ding, Xiaofeng Zhou, Anxun Wang
Article Number: 475
Published online on: 24 August 2026

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Article Open Access

Pazopanib treatment for primary cardiovascular sarcoma: A retrospective observational study and literature review

Shintaro Yamanaka, Yoshihiro Yakushijin, Shinji Hasebe, Shoichiro Yamamoto, Tomomi Fujii, Riko Kitazawa, Taketsugu Fujibuchi, Teruki Kidani, Masaki Maruta
Article Number: 474
Published online on: 21 August 2026

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Case Report Open Access

Primary cutaneous angiosarcoma of the scalp initially misdiagnosed as cellulitis in a 95‑year‑old Asian man: A case report

Baopeng Qi, Qianru Li, Yuan Gao, Yuanyu Tang, Yang Yu
Article Number: 473
Published online on: 21 August 2026

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Article Open Access

Colorectal cancer and tumor vaccines (Review)

Jianshuang Ma, Congming Xiang, Dong Xia
Article Number: 472
Published online on: 21 August 2026

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Article Open Access

Pre‑radiotherapy modified prognostic nutritional index predicts acute radiation enteritis in patients with cervical cancer undergoing radiotherapy: A retrospective study

Yani Zou, Rui Huang, Wenqiang Qin, Chunqiu Wu, Wei Zhang
Article Number: 471
Published online on: 21 August 2026

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Correction Open Access

[Corrigendum] MicroRNA‑101 suppresses progression of lung cancer through the PTEN/AKT signaling pathway by targeting DNA methyltransferase 3A

Lumin Wang, Jiayi Yao, Hongfei Sun, Kang He, Dongdong Tong, Tusheng Song, Chen Huang
Article Number: 470
Published online on: 20 August 2026

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Article Open Access

Boost delivery in hypofractionated breast cancer radiotherapy: A registry‑based analysis of treatment patterns and survival

Karoline Elisabeth Horry, Dirk Vordermark, Daniel Medenwald, Jörg Andreas Müller
Article Number: 469
Published online on: 18 August 2026

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Article

Effect of perioperative nutritional status, inflammatory response and postoperative chemotherapy on survival after gastrectomy for advanced gastric cancer

Yoshinori Fujiwara, Shunji Endo, Masaharu Higashida, Masaaki Hori, Yoko Endo, Ryoko Makieda, Akihide Fujii, Miyoko Kobayashi, Kazuhiko Yoshimatsu, Tomio Ueno
Article Number: 468
Published online on: 18 August 2026

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Retraction Open Access

[Retracted] miR‑185‑5p targets ROCK2 and inhibits cell migration and invasion of hepatocellular carcinoma

Yuexiang Niu, Gongen Tang
Article Number: 467
Published online on: 17 August 2026

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Article

OLFML2A expression in acute myeloid leukemia, with exploratory findings in acute lymphoblastic leukemia: Prognostic significance and re‑analysis of public single‑cell transcriptomic data

Xuan Lu, Jinlian Li, Xinru Zhao, Wanchuan Zhuang, Xingxing Chai
Article Number: 466
Published online on: 17 August 2026

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Article Open Access

Identifying an appropriate endogenous control for real‑time PCR of microRNAs in colorectal liver metastases: A comparison of 18s rRNA and small nuclear RNA RNU6B

Clemens Franz, Sibylle Hartmann, Alexis Ulrich, Georgios Polychronidis, Christoph Kahlert, Fee Klupp, Mohammed Al‑Saeedi
Article Number: 465
Published online on: 17 August 2026

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Article Open Access

Analysis of DNA methylation markers for diagnosing cervical precancer and cancer: A single‑center cross‑sectional study

Xue Chen, Jialing Li, Li Tian, Xinshu Li, Jingwen Guo, Liling He, Shulian Mao, Xitang Yang, Hua Guo
Article Number: 464
Published online on: 17 August 2026

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Article Open Access

Flavokawain A inhibits high glucose‑induced malignant progression of lung cancer cells by suppressing PRMT5‑mediated PTEN neddylation and nuclear translocation

Lei Zheng, Juan Li, Chao Song, Leping Shi, Qian Zhou, Yuyao Guan
Article Number: 463
Published online on: 14 August 2026

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Review Open Access

Metabolic heterogeneity and functional diversity of cancer-associated fibroblasts in gastric cancer (Review)

Qilu Fang, Neng Lv, Shuwei Yu, Jia Wang, Wenxiu Xin
Article Number: 462
Published online on: 14 August 2026

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Article Open Access

Preoperative CA125 and metabolic factors associated with high‑risk pathology in endometrial cancer

Yinuo Wang, Yueqi Yan, Wen Sun, Yiting Gao, Bingli Qi, Xia Li, Shouze Liu, Shikai Liu
Article Number: 461
Published online on: 14 August 2026

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Article Open Access

EGR1 regulates IGF‑1‑stimulated pancreatic cancer cell invasion by increasing IL‑11 expression 

Yena Choi, Euitaek Jung, Junekyu Han, Soon Young Shin
Article Number: 460
Published online on: 13 August 2026

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Review Open Access

Claudin‑18.2: Molecular mechanisms to clinical translation in solid tumors (Review)

Minjie Zhang, Dawei Wu, Yu Tang, Ning Li, Xinhua Yan
Article Number: 459
Published online on: 12 August 2026

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Case Report Open Access

Probable cavernous sinus‑adjacent meningeal metastasis from esophageal squamous cell carcinoma: A case report

Heng Di Zhang, Bin He, Jing Jing Peng, Ting Yu, Fang Yuan Kong, Ling Zhang
Article Number: 458
Published online on: 12 August 2026

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Case Report Open Access

Immunotherapy combined with anti‑angiogenic therapy, radiotherapy and chemotherapy for the treatment of giant pelvic osteosarcoma: A case report and literature review

Qingying Yan, Jiewen Yang, Yunxia Liu, Miao Cheng, Zhen Wang, Jialu Chen, Yefeng Xu
Article Number: 457
Published online on: 12 August 2026

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Expression of Concern Open Access

[Expression of Concern] Obesity accelerates murine gastric cancer growth by modulating the Sirt1/YAP pathway

Hai-Jun Li, Jun-Ke Fu, Xiang-Ming Che, Lin Fan, Yong Zhang, E Bai
Article Number: 456
Published online on: 12 August 2026

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Article Open Access

Tumor suppressor syntaxin binding protein 1 regulates alternative splicing of DNA repair genes related to radiation sensitivity in breast cancer cells

Meng Zhang, Xiaoxue Zhang, Qian Rou, Ying Liu, Ailifeire Abudujiapaer, Minghui Li, Huaixiong Wang, Fang Cheng
Article Number: 455
Published online on: 12 August 2026

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Retraction Open Access

[Retracted] 2’,4’‑dihydroxychalcone, a flavonoid isolated from Herba oxytropis, suppresses PC‑3 human prostate cancer cell growth by induction of apoptosis 

Yuqing Sheng, Mingchang Zou, Yan Wang, Qiheng Li
Article Number: 454
Published online on: 11 August 2026

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Case Report Open Access

Mixed carcinoma transdifferentiation of bladder urothelial carcinoma after chemotherapy: A case report

Liwei Zhao, Jiaguo Huang, Zhanwen Dong, Ji Sun, Runmiao Hua, Xuliang Wang, Kai Wang
Article Number: 453
Published online on: 10 August 2026

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Case Report Open Access

Primary leiomyosarcoma of the lumbar soft tissue treated with multimodal therapy, including anlotinib: A case report

Jia-Huan Li, De-Xiang Liao, Zhen Hu, Zhi-Yong Zhang, Dan-Dan Ma, Wei-Dong Jin, Tao Fu
Article Number: 452
Published online on: 10 August 2026

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Expression of Concern Open Access

[Expression of Concern] Valosin‑containing protein promotes metastasis of osteosarcoma through autophagy induction and anoikis inhibition via the ERK/NF‑κβ/beclin‑1 signaling pathway

Xin Hua Long, Yun Fei Zhou, Min Lan, Shan Hu Huang, Zhi Li Liu, Yong Shu
Article Number: 451
Published online on: 07 August 2026

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Article Open Access

Prognostic value of the CONUT score in newly diagnosed diffuse large B‑cell lymphoma

Sema Seçilmiş, Hacer Berna Afacan Öztürk, Birgül Ay Karakuş, Asena Dikyar, Kadir Acar, Ahmet Kürşad Güneş
Article Number: 450
Published online on: 06 August 2026

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Article Open Access

DHX15 as a novel immune‑related prognostic biomarker in breast cancer: An integrated bioinformatics analysis with in vitro functional validation

Fan Li, Qin Yue, Jing Li
Article Number: 449
Published online on: 05 August 2026

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Case Report Open Access

Emergence of KRAS mosaicism with multiple variants during treatment with alectinib in ALK‑positive metastatic non‑small cell lung cancer: A case report

Alizée Simon, Gautier Treffel, Guillaume Pax, Guillaume Gauchotte, Marie Husson, Idrissia Hanriot, Agnès Leroux, Jean-Louis Merlin, Alexandre Harlé, Pauline Gilson
Article Number: 448
Published online on: 05 August 2026

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Expression of Concern Open Access

[Expression of Concern] Circular RNA ATAD1 is upregulated in acute myeloid leukemia and promotes cancer cell proliferation by downregulating miR‑34b via promoter methylation  

Yarong Wu, Bingjun Gao, Xiaolei Qi, Liyun Bai, Bixin Li, Hongjing Bao, Xi Wu, Xiaoyun Wu, Yuxia Zhao
Article Number: 447
Published online on: 05 August 2026

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Article

Preliminary study on the efficacy of pazopanib combined with toripalimab as first‑line therapy for metastatic renal cell carcinoma: Real‑world data from a single center

Bin Wang, Tianjun Xing, Hongyu Liu, Xuebing Han, Kai Wu
Article Number: 446
Published online on: 05 August 2026

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Review Open Access

Subtype‑specific mechanisms of lipid metabolism in gynecological malignancies and novel targeted intervention strategies (Review)

Yidan Ran
Article Number: 445
Published online on: 04 August 2026

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Review Open Access

Chrono‑immunotherapy in genitourinary oncology: From emerging evidence to clinical translation (Review)

Osama Zein Deen, Xin Ye, Patsy Lee, Roxana Astani, Georg Bjarnason, Christian Kollmannsberger, Bernhard Eigl, Guliz Ozgun
Article Number: 444
Published online on: 03 August 2026

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Case Report Open Access

Imaging features and clinical management of mesenteric cavernous lymphangioma: A case report and literature review

Zhongze Zhao, Ermin Cai, Tong Zhou, Jianju Feng, Lingzhi Gu
Article Number: 443
Published online on: 03 August 2026

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Article Open Access

Association between the expression of GSTP1 and mutant p53, poor chemotherapy response and metastasis in patients with osteosarcoma

Bangkit Primayudha, Evelina Kodrat, Yogi Prabowo, Aryadi Kurniawan, Nurjati Chairani Siregar, Muhamad Naseh Sajadi Budi Irawan, Rahadyan Magetsari, I Gede Eka Wiratnaya, Istan Irmansyah Irsan, Achmad Fauzi Kamal
Article Number: 442
Published online on: 03 August 2026

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Article Open Access

Astragaloside IV suppresses triple‑negative breast cancer cell migration and invasion by targeting BCAT1‑mediated branched‑chain amino acid metabolism

Yi-Ting Liu, Lu Zhang, Xiao-Dong Sun
Article Number: 441
Published online on: 03 August 2026

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Article Open Access

LC‑MS/MS‑based clinical value exploration of the methionine cycle in luminal breast cancer

Wenxuan Wu, Yifeng Tu, Han Yao, Yajun Mao, Changfei Mao, Feifei Xu, Zhongcheng Wang
Article Number: 440
Published online on: 03 August 2026

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Article

Accuracy of percutaneous ultrasound‑guided needle biopsy of abdominal lymph nodes for the diagnosis of malignant disease

Camilla Mazzoni, Lisa Argnani, Davide Di Benedetto, Sofia Maria Bakken, Beatrice Casadei, Cinzia Pellegrini, Leonardo De Marco, Marta Machado, Alessandro Broccoli, Pier Luigi Zinzani, Carla Serra
Article Number: 439
Published online on: 03 August 2026

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Retraction Open Access

[Retracted] Esomeprazole affects the proliferation, metastasis, apoptosis and chemosensitivity of gastric cancer cells by regulating lncRNA/circRNA‑miRNA‑mRNA ceRNA networks

Qian Xu, Xiyun Jia, Qian Wu, Lei Shi, Zihan Ma, Nan Ba, Han Zhao, Xingzhou Xia, Zisen Zhang
Article Number: 438
Published online on: 03 August 2026

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Case Report Open Access

Papillary thyroid carcinoma in a patient with long‑standing chronic lymphocytic leukemia: A case report

Jiaxiang Ma, Tieying Gan, Ailin Song, Hongyou Tian, Shaoce Xu, Lei Zhao
Article Number: 437
Published online on: 30 July 2026

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Review Open Access

Current status and targeted therapies in endometrial cancer: Molecular classification‑driven treatment strategies (Review)

Xinyu Li, Jie Liu, Fang Huang, Xinyue Deng, Mingxuan Chen, Wen Mou, Wenxia Liu
Article Number: 436
Published online on: 30 July 2026

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Article Open Access

Role of lipid‑associated fibroblasts and their signature genes FABP4, CD36 and ABCA8 in gastric cancer progression

Junqun Liao, Lin Wu, Li Zhou, Qiao Ling, Piyun Zhang
Article Number: 435
Published online on: 30 July 2026

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Correction Open Access

[Corrigendum] Repositioning of duloxetine to target pancreatic stellate cells

Akiko Sagara, Kohei Nakata, Sokichi Matsumoto, Weiyu Guan, Tomohiko Shinkawa, Chika Iwamoto, Naoki Ikenaga, Kenoki Ohuchida, Masafumi Nakamura
Article Number: 434
Published online on: 30 July 2026

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Article

Influence of the second primary cancer on clinical outcomes of nasopharyngeal carcinoma following definitive chemoradiotherapy

Shu-Chin Yang, Chung-Han Ho, Li-Tsun Shieh, Sung-Wei Lee, Chia-Chun Chen, Sheng-Yow Ho
Article Number: 433
Published online on: 29 July 2026

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Review Open Access

ETS transcription factor ELK3: Molecular insights and translational horizons in cancer (Review)

Zhenzhe Liu, Zhong Wei, Zhensheng Li, Liqiang Zhou
Article Number: 432
Published online on: 29 July 2026

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Review Open Access

Bone niche‑driven antitumor immune failure in osteosarcoma: Mechanisms and therapeutic implications (Review)

Bolin Tang, Yuhuai Wu, Jianping Liu, Rui Pan
Article Number: 431
Published online on: 29 July 2026

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Article Open Access

Deep learning model based on CT images to predict Ki‑67 expression in renal carcinoma

Dan Shen, Hongmei Li, Bingye Shi, Tao Ma, Bin Zhou, Chao Gao, Yibo Liu, Zhenyu Cui
Article Number: 430
Published online on: 29 July 2026

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Retraction Open Access

[Retracted] Epigenetic silencing of microRNA‑199a‑5p promotes the proliferation of non‑small cell lung cancer cells by increasing AKAP1 expression

Nengli Yang, Yafeng Liang, Tianqi Zhu, Yanxiao Long, Zhe Chen, Xuezheng Zhang, Liuming Jiang
Article Number: 429
Published online on: 29 July 2026

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Article Open Access

Investigation of CRP and NLR as potential biomarkers for redefining biological borderline resectable pancreatic cancer

Keishi Kawasaki, Hidehiro Tajima, Teppei Tatsuoka, Musashi Takada, Soya Meguro, Hirotaka Ishido, Hideyuki Yoshitomi
Article Number: 428
Published online on: 28 July 2026

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Article Open Access

FAM122B acts as an independent poor prognostic factor and promotes the malignant biological behaviors of low‑grade glioma

Hao Wang, Tengfei Guo, Yanbo Gao, Yi Zhou, Rongjun Qian
Article Number: 427
Published online on: 28 July 2026

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Article Open Access

A nomogram based on immunohistochemistry and lymphocyte‑to‑monocyte ratio for predicting risk stratification in endometrial carcinoma

Yunyun Chen, Jianwei Li, Li Yan, Peili Liu, Fanfei Meng, Yajun Zhang
Article Number: 426
Published online on: 28 July 2026

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Correction Open Access

[Corrigendum] Effects of Platycodin D on apoptosis, migration, invasion and cell cycle arrest of gallbladder cancer cells

Xiaoyu Zhang, Tianyu Zhai, Zhenyu Hei, Di Zhou, Longyang Jin, Chao Han, Jiandong Wang
Article Number: 425
Published online on: 27 July 2026

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Case Report Open Access

Evaluation of limb function after treatment with chemotherapy and carbon ion radiotherapy for Ewing sarcoma of the scapula: A report of three cases 

Noriko Kato, Takashi Yanagawa, Masahiko Okamoto, Tatsuya Ohno, Hirotaka Chikuda
Article Number: 424
Published online on: 23 July 2026

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Correction Open Access

[Corrigendum] Effect of antioxidants coenzyme Q10 and β‑carotene on the cytotoxicity of vemurafenib against human malignant melanoma

Changkun Hu, Yuan Huang, Peixiao Luo, Yixin Yang
Article Number: 423
Published online on: 23 July 2026

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November-2026 Volume 32 Issue 5

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Impact Factor: 2.1

CiteScore: 3.7

CiteScore Rank: Q3: #233/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Clinicopathological characteristics and potential impact of previous treatment history in metachronous contralateral breast cancer: Insights from a real‑world retrospective study

Ritsuko Sasaki, Koji Yamamoto, Kotaro Iijima, Masami Arai, Mitsue Saito, Goro Kutomi
Article Number: 492
Published online on: 04 September 2026

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Article Open Access

Transcriptional activation of GSTP1 by ANXA3 is associated with cisplatin sensitivity in colorectal cancer cells

Ximao Cui, Xin Xu, Xiao Yuan, Kunkun Han, Han Wang, Shun Zhang, Chiye Ma, Renhao Hu, Xiaohua Jiang, Yili Yang
Article Number: 491
Published online on: 04 September 2026

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Case Report Open Access

Seven‑year follow‑up demonstrating sustained survival following 125I seed brachytherapy in an elderly patient with lip squamous cell carcinoma and Alzheimer's disease: A case report

Guangsheng Zhao, Xinyu Zhou, Shunhang Yin, Fang Xu, Licai Xu, Qiushi Wang, Jun Zhou, Song Liu
Article Number: 490
Published online on: 03 September 2026

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Retraction Open Access

[Retracted] Effects and mechanisms of blocking the hedgehog signaling pathway in human gastric cancer cells

Hongbing Gu, Xu Li, Congzhi Zhou, Yugang Wen, Yang Shen, Lisheng Zhou, Jikun Li
Article Number: 489
Published online on: 03 September 2026

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