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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
February 2013 Volume 5 Issue 2

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Review

Active autophagy in the tumor microenvironment: A novel mechanism for cancer metastasis (Review)

Yinghua Xu, Xiaoping Xia, Hongming Pan
Pages: 411-416
Published online on: 07 November 2012

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Review

Function and mechanism by which interferon regulatory factor‑1 inhibits oncogenesis (Review)

Fei‑Fei Chen, Guan Jiang, Kerui Xu, Jun‑Nian Zheng
Pages: 417-423
Published online on: 28 November 2012

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Review

The evolution in melanoma treatment as a reflection of precision-oriented medicine (Review)

Igal Kushnir, Ofer Merimsky
Pages: 424-426
Published online on: 05 December 2012

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Article

Factors affecting the sensitivity of human-derived esophageal carcinoma cell lines to 5-fluorouracil and cisplatin

Tetsuya Minegaki, Kohji Takara, Ryohei Hamaguchi, Masayuki Tsujimoto, Kohshi Nishiguchi
Pages: 427-434
Published online on: 05 November 2012

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Article

Observational study on the efficacy and safety of erlotinib in patients with non-small cell lung cancer

Takayuki Kaburagi, Hiroaki Satoh, Kenji Hayashihara, Takeshi Endo, Nobuyuki Hizawa, Koichi Kurishima, Yoshihiro Nishimura, Toshio Hashimoto, Hiroyuki Nakamura, Koji  Kishi, Masaharu Inagaki, Takeshi Nawa, Hideo Ichimura, Hiroichi  Ishikawa, Katsunori Kagohashi, Toshihiko  Fukuoka, Yoko Shinohara, Koichi  Kamiyama, Yukio  Sato, Mitsuaki  Sakai, Takeshi Matsumura, Keiko Uchiumi, Kinya Furukawa
Pages: 435-439
Published online on: 27 November 2012

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Article

Synergistic interaction between sorafenib and gemcitabine in EGFR‑TKI‑sensitive and EGFR‑TKI‑resistant human lung cancer cell lines

Jing Li, Yue‑Yin Pan, Ying Zhang
Pages: 440-446
Published online on: 07 November 2012

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Article

Clinical outcomes of giant cell tumor of bone treated with bone cement filling and internal fixation, and oral bisphosphonates

Xiuchun Yu, Ming Xu, Songfeng Xu, Qing Su
Pages: 447-451
Published online on: 20 November 2012

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Article

Investigation of the expression patterns and correlation of DNA methyltransferases and class I histone deacetylases in ovarian cancer tissues

Yifeng Gu, Peifang Yang, Qing Shao, Xia Liu, Sheng Xia, Miaomiao Zhang, Huaxi Xu, Qixiang Shao
Pages: 452-458
Published online on: 03 December 2012

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Case Report

Synchronous solid neuroendocrine breast carcinoma and abdominal lymphoma: A case report and review of the literature

Miguel Alonso-Ruano, Eugeni López-Bonet, Maria   Victoria Huerta‑Anaya, Ester Vila-Camps, Luis Bernadó, Francesc Tuca‑Rodríguez, Pedro Suarez-Pumariega, Javier A. Menendez
Pages: 459-462
Published online on: 23 November 2012

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Article

Effects of different sequences of pulmonary artery and vein ligations during pulmonary lobectomy on blood micrometastasis of non-small cell lung cancer

Ping-Ping Song, Weidi Zhang, Baijiang Zhang, Qi Liu, Jiajun Du
Pages: 463-468
Published online on: 09 November 2012

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Case Report

Epidermoid cyst arising from an intrapancreatic accessory spleen: A case report and review of the literature

Ran Hong, Namkyu Choi, Kyunghoon Sun, Sharon Lim, Yunju Han
Pages: 469-472
Published online on: 04 December 2012

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Article

High expression of FER tyrosine kinase predicts poor prognosis in clear cell renal cell carcinoma

Can Wei, Song Wu, Xianxin Li, Yadong Wang, Rui Ren, Yongqing Lai, Jiongxian Ye
Pages: 473-478
Published online on: 16 November 2012

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Case Report

Solitary plasmacytoma of the skull: Two case reports

Lun Dong, Xian Zhang, Hengzhu Zhang, Ruihong Song, Xuewen Gu, Liang He
Pages: 479-482
Published online on: 26 November 2012

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Article

Analgesic-antitumor peptide induces apoptosis and inhibits the proliferation of SW480 human colon cancer cells

Yu Gu, Shen-Lin Liu, Wen-Zheng Ju, Chang-Yin Li, Peng Cao
Pages: 483-488
Published online on: 27 November 2012

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Article

An engineered three-dimensional gastric tumor culture model for evaluating the antitumor activity of immune cells in vitro

Peiming Sun, Yingxin Xu, Xiaohui Du, Ning Ning, Huiwei Sun, Wentao Liang, Rong Li
Pages: 489-494
Published online on: 09 November 2012

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Case Report

Rapidly evolving asymptomatic eosinophilia in a patient with lung adenocarcinoma causes cognitive disturbance and respiratory insufficiency: Case report

Cheng-Hsiang Lo, Yee-Min Jen, Wen-Chiuan Tsai, Ping-Ying Chung, Woei-Yau Kao
Pages: 495-498
Published online on: 09 November 2012

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Article

Analysis of the expression of the Notch3 receptor protein in adult lung cancer

Min Zhou, Wei-Yun Jin, Zhi-Wen Fan, Rui-Chao Han
Pages: 499-504
Published online on: 19 November 2012

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Article

Astrocyte elevated gene‑1 regulates osteosarcoma cell invasion and chemoresistance via endothelin‑1/endothelin A receptor signaling

Bo Liu, Yi Wu, Dan Peng
Pages: 505-510
Published online on: 03 December 2012

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Article

Evaluating the effect of high-intensity focused ultrasound therapy on liver tumors using multislice CT perfusion

Xinshan Cao, Xingyue Jiang
Pages: 511-514
Published online on: 10 December 2012

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Article

Simultaneous cytomorphological and multiparameter flow cytometric analysis of ALK-positive anaplastic large cell lymphoma in children

Hongqiang Shen, Yongmin Tang, Xiaojun Xu, Hongfeng Tang, Weizhong Gu
Pages: 515-520
Published online on: 19 November 2012

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Article

Function and mode of action of cytohesins in the epidermal growth factor pathway in colorectal cancer cells

Tao Pan, Junfeng Sun, Jun Zhou, Zhixuan Fu, Yiwang Hu, Shu Zheng, Suzhan Zhang
Pages: 521-526
Published online on: 05 December 2012

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Article

Dasatinib inhibits primary melanoma cell proliferation through morphology‑dependent disruption of Src‑ERK signaling

Jianghong Wu, Xin Liao, Bo Yu, Bing Su
Pages: 527-532
Published online on: 10 December 2012

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Article

The expression of phospholipase A2 group X is inversely associated with metastasis in colorectal cancer

Masaya Hiyoshi, Joji Kitayama, Shinsuke Kazama, Yoshitaka  Taketomi, Makoto Murakami, Nelson H. Tsuno, Kumiko  Hongo, Manabu  Kaneko, Eiji Sunami, Toshiaki Watanabe
Pages: 533-538
Published online on: 10 December 2012

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Article

Adrenal lymphangioma removed by a retroperitoneoscopic procedure

Ben Liu, Yanyuan Li, Shuo Wang
Pages: 539-540
Published online on: 04 December 2012

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Case Report

A surgical approach to giant condyloma (Buschke‑Löwenstein tumour) with underlying superficial vulvar carcinoma: A case report

Josko Zekan, Davor Petrovic, Samer El‑Safadi, Maja Banovic, Davor Hulina, Zlatko Hrgovic
Pages: 541-543
Published online on: 14 November 2012

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Article

Identification of MXRA5 as a novel biomarker in colorectal cancer

Guang-Hui Wang, Ling Yao, Hong-Wei Xu, Wen-Tao Tang, Ji‑Hong Fu, Xiao-Fang Hu, Long Cui, Xue-Min Xu
Pages: 544-548
Published online on: 21 November 2012

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Case Report

Pathological and computed tomography findings of lymphoepithelioma‑like gastric carcinoma with epithelioid granulomas: A case report

Shuguang Liu, Long Jin, Xiaoyan Xu, Ni Lin, Bin Lei, Hong Shen
Pages: 549-551
Published online on: 12 December 2012

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Article

Expression of stem cell factor in gastrointestinal stromal tumors: Implications for proliferation and imatinib resistance

Xiao-Wei Hou, Chen-Guang Bai, Xiao-Hong Liu, Cen Qiu, Ling Huang, Jing-Jing Xu, Da-Lie Ma
Pages: 552-558
Published online on: 09 November 2012

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Article

The incidence and prognostic value of HER2 overexpression and cyclin D1 expression in patients with gastric or gastroesophageal junction adenocarcinoma in Israel

Gil Bar-Sela, Dov Hershkovitz, Nissim Haim, Orit Kaidar-Person, Katerina Shulman, Ofer Ben-Izhak
Pages: 559-563
Published online on: 16 November 2012

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Article

High expression of ZEB1 correlates with liver metastasis and poor prognosis in colorectal cancer

Guang-Jun Zhang, Tong Zhou, Hong-Peng Tian, Zuo-Liang Liu, Shu-Sen Xia
Pages: 564-568
Published online on: 14 November 2012

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Article

rs12976445 variant in the pri‑miR‑125a correlates with a lower level of hsa‑miR‑125a and ERBB2 overexpression in breast cancer patients

Tomasz P. Lehmann, Konstanty Korski, Mathew Ibbs, Piotr  Zawierucha, Sylwia Grodecka‑Gazdecka, Paweł P. Jagodziński
Pages: 569-573
Published online on: 22 November 2012

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Article

Expression of C-X-C chemokine receptor types 1/2 in patients with gastric carcinoma: Clinicopathological correlations and significance

Jun Pu Wang, Wan Ming Hu, Kuan Song Wang, Jun Yu, Bai Hua Luo, Chang Wu, Zhi Hong Chen, Geng Qiu Luo, Yu Wu Liu, Qin Lai Liu, Yan Xiao, Hai Yan Zhou, Xiao Jing Yang, Hai Ying Jiang, Jing He Li, Ji Fang Wen
Pages: 574-582
Published online on: 23 November 2012

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Article

p73 expression is associated with cellular chemosensitivity in human non-small cell lung cancer cell lines

Kaishan Liu, Xiaomei Zhuang, Zhuoying Mai
Pages: 583-587
Published online on: 19 November 2012

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Article

Lenalidomide induces apoptosis and alters gene expression in non-small cell lung cancer cells

Karam Kim, Sungkwan An, Hwa Jun Cha, Yeong Min Choi, Sung Jin Choi, In-Sook An, Hong Ghi Lee, Yoo Hong Min, Su-Jae Lee, Seunghee Bae
Pages: 588-592
Published online on: 30 November 2012

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Article

Staging recurrent ovarian cancer with 18FDG PET/CT

Sanja Dragosavac, Sophie Derchain, Nelson M.G. Caserta, Gustavo De Souza
Pages: 593-597
Published online on: 13 December 2012

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Case Report

Cancer of the supernumerary ovary in Mayer‑Rokitansty‑Küster‑Hauser Syndrome: A case report

Hyo Sook Bae, Min Ji Ryu, In Sun Kim, Sun Haeng Kim, Jae Yun Song
Pages: 598-600
Published online on: 12 December 2012

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Article

Pneumocystis jiroveci pneumonia and colonization in patients with advanced lung cancer

Yosuke Togashi, Katsuhiro Masago, Yutaka Ito, Yuichi Sakamori, Chiyuki  Okuda, Akiko Fukuhara, Hiroki Nagai, Young Hak Kim, Michiaki Mishima
Pages: 601-604
Published online on: 29 November 2012

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Article

A new t(9;11;20;22)(q34;p11.2;q11.21;q11) in a Philadelphia-positive chronic myeloid leukemia case

Walid Al-Achkar, Abdulsamad Wafa, Thomas Liehr
Pages: 605-608
Published online on: 21 November 2012

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Article

Effects of cancer-associated fibroblasts on the migration and invasion abilities of SGC-7901 gastric cancer cells

Chengyi Hu, Zhengcai Wang, Lili Zhai, Miling Yang, Lihui  Shan, Cuicui Chai, Ming Liu, Lifeng Wang
Pages: 609-612
Published online on: 09 November 2012

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Article

Pancreatic cyst fluid analysis for differential diagnosis between benign and malignant lesions

Renata Talar‑Wojnarowska, Marek Pazurek, Lukasz Durko, Malgorzata  Degowska, Grazyna Rydzewska, Jacek Smigielski, Adam Janiak, Marek Olakowski, Paweł  Lampe, Piotr Grzelak, Ludomir Stefanczyk, Ewa Malecka‑Panas
Pages: 613-616
Published online on: 12 December 2012

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Article

A novel cytogenetic abnormality t(7;8)(p11.2:q11.2) and a four-way Philadelphia translocation in an imatinib mesylate‑resistant chronic myeloid leukemia patient

Walid Al‑Achkar, Abdulmunim Aljapawe, Suher Almedani, Thomas Liehr, Abdulsamad Wafa
Pages: 617-620
Published online on: 21 November 2012

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Article

Magnetic resonance imaging of the brain in survivors of childhood acute lymphoblastic leukemia

Mohamed Ahmed Badr, Tamer Hasan Hassan, Khaled   Mohamed El‑Gerby, Mohamed El-Sayed Lamey
Pages: 621-626
Published online on: 12 December 2012

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Case Report

Giant extragastrointestinal stromal tumor in the transverse mesocolon concomitant with gastric cancer in an elderly patient: Case report

Dong Xue, Hongqiang Chen, Yuxin Chen
Pages: 627-630
Published online on: 16 November 2012

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Article

Functional epidermal growth factor gene polymorphisms and risk of gastric cancer

Zhen Zhan, Yajun Chen, Juan Wu, Junfeng Zhang, Shujuan Tong, Chunbing Zhang, Yaping Yang
Pages: 631-636
Published online on: 22 November 2012

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Article

Bevacizumab-containing regimens after cetuximab failure in Kras wild-type metastatic colorectal carcinoma

Ka On Lam, Victor Ho Fun Lee, Rico Kin Yin Liu, To Wai Leung, Dora Lai Wan Kwong
Pages: 637-640
Published online on: 26 November 2012

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Article

Chemosensitizing activities of cyclotides from Clitoria ternatea in paclitaxel-resistant lung cancer cells

Zhang Sen, Xiao Kai Zhan, Jin Jing, Zhang Yi, Zhou Wanqi
Pages: 641-644
Published online on: 22 November 2012

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Article

Endogenous PGE2 induces MCP‑1 expression via EP4/p38 MAPK signaling in melanoma

Mingrui Tang, Yuxin Wang, Sihuan Han, Shu Guo, Nan Xu, Jiayan Guo
Pages: 645-650
Published online on: 27 November 2012

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Article

A tailored health surveillance program unveils a case of MALT lymphoma in an HCV-positive health-care worker

Venerando Rapisarda, Andrea Marconi, Saverio Candido, Daria Nicolosi, Mario Salmeri, Pietro Gangemi, Lidia Proietti, Demetrios A. Spandidos, Massimo Bracci, Cettina Fenga, Massimo Libra
Pages: 651-654
Published online on: 15 November 2012

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Article

Anticancer effects of 3,3'-diindolylmethane are associated with G1 arrest and mitochondria-dependent apoptosis in human nasopharyngeal carcinoma cells

Yu Xu, Jin Zhang, Wendan Shi, Yun Liu
Pages: 655-662
Published online on: 05 December 2012

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Article

Mini-array of multiple tumor-associated antigens (TAAs) in the immunodiagnosis of breast cancer

Hua Ye, Changqing Sun, Pengfei Ren, Liping Dai, Bo  Peng, Kaijuan Wang, Wei Qian, Jianying Zhang
Pages: 663-668
Published online on: 05 December 2012

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Article

The glial fibrillary acidic protein promoter directs sodium/iodide symporter gene expression for radioiodine therapy of malignant glioma

Wei Li, Jian Tan, Peng Wang, Ning Li, Fuhai Zhang
Pages: 669-674
Published online on: 03 December 2012

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Article

Inhibition of MCF-7 breast cancer cell-induced platelet aggregation using a combination of antiplatelet drugs

Lian Lian, Wei Li, Zhen-Yu Li, Yi-Xiang Mao, You-Tao Zhang, Yi-Ming Zhao, Kai Chen, Wei-Ming Duan, Min Tao
Pages: 675-680
Published online on: 13 December 2012

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Article

Paraneoplastic cerebellar degeneration associated with ovarian cancer

Alessia Erika Russo, Simona Scalone, Giulia Costanza Leonardi, Aurora Scalisi, Giorgio Giorda, Roberto Sorio
Pages: 681-683
Published online on: 07 November 2012

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Article

Cisplatin for small cell lung cancer: Associated publications in Science Citation Index Expanded

Yuh‑Shan Ho, Kensuke Nakazawa, Shinya Sato, Tomohiro Tamura, Koichi Kurishima, Hiroaki Satoh
Pages: 684-688
Published online on: 15 November 2012

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Article

Comprehensive clinical and pathological analysis of three rare vascular tumor cases

Fu Li, Lixia Ma, Leling Zhang, Libo Zheng, Xin Lv, Jihua Fu
Pages: 689-693
Published online on: 13 November 2012

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Article

Determining the effect of transforming growth factor-β1 on cdk4 and p27 in gastric cancer and cholangiocarcinoma

Sung Ryol Lee, Jae Wook Shin, Hyung Ook Kim, Byung  Ho Son, Chang Hak Yoo, Jun Ho Shin
Pages: 694-698
Published online on: 13 November 2012

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Case Report

Digestive tract hemorrhage due to complications with gastrointestinal stromal tumor treated with sunitinib: A case report

Yan Liu, He-Long Zhang, Ye Zhang, Jia-Zhuan Mei, Hong-Wei Lin, Yan‑Wei  Guo, Rui-Jun Li, Xiang-Rui Meng, Gui-Ju Liu, Min Li, Peng Xiao, Hua Bai
Pages: 699-701
Published online on: 28 November 2012

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Article

In vitro study of low intensity ultrasound combined with different doses of PDT: Effects on C6 glioma cells

Jian-Hua Li, Zhi-Qiang Chen, Zheng Huang, Qi Zhan, Fu‑Bin  Ren, Jing-Ye Liu, Wu Yue, Zhi Wang
Pages: 702-706
Published online on: 04 December 2012

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Article

Retrospective analysis of 264 multiple myeloma patients

Chuanying Geng, Nian Liu, Guangzhong Yang, Aijun Liu, Yun Leng, Huijuan Wang, Lihong Li, Yin Wu, Yanchen Li, Wenming Chen
Pages: 707-713
Published online on: 09 November 2012

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Case Report

Fatal pneumonitis associated with postoperative intensity-modulated radiotherapy in lung cancer: Case report and review

Yan Hu, Jingjing Li, Xiaoyan Su
Pages: 714-716
Published online on: 30 November 2012

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Article

The mTOR inhibitor AZD8055 inhibits proliferation and glycolysis in cervical cancer cells

Shaoru Li, Yan Li, Ruili Hu, Weihua Li, Haifeng Qiu, Honghua Cai, Shijin Wang
Pages: 717-721
Published online on: 04 December 2012

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Article

Baicalein induces apoptosis in esophageal squamous cell carcinoma cells through modulation of the PI3K/Akt pathway

Hong-Bo Zhang, Ping Lu, Qing-Yin Guo, Zhen-Hua Zhang, Xiang-Yu Meng
Pages: 722-728
Published online on: 10 December 2012

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Journal Cover
June-2026 Volume 31 Issue 6

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Early postoperative complications and patient‑reported quality of life following breast‑conserving surgery with intraoperative radiotherapy: A prospective cohort study

Hongmei Han, Xuwen Liu, Baozhong Zhang, Jingjing Liu, Jing Wang, Qingsong Pang
Article Number: 268
Published online on: 27 April 2026

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Exploring the mechanism of action of glaucocalyxin D against acute myeloid leukemia using network pharmacology, molecular docking and cellular experiments

Lian Chen, Weixian Yang, Weiqing Zhang, Heng Luo, Chen Yan
Article Number: 267
Published online on: 27 April 2026

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Special Issue

Advances in cerebrospinal fluid biomarkers for the diagnosis, treatment and monitoring of leptomeningeal metastases (Review)

Huaixu Li, Wenwen Fan, Fengchun Mu, Cheng Fang, Ting Xiao, Jinghai Wan, Hongqing Cai
Article Number: 266
Published online on: 27 April 2026

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Article Open Access

Exploration of the effect and mechanism of Eclipta prostrata L. against gastric cancer based on network pharmacology and experimental verification

Weizhou Yu, Xiaohui Ni, Jing Wang, Wei Xia, Xinya Shen, Fan Qiu, Yuping Chen
Article Number: 265
Published online on: 27 April 2026

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Article Open Access

Neoadjuvant radiotherapy for resectable hepatocellular carcinoma with vascular invasion: A systematic review and meta‑analysis

Yuhao Su, Yuxin Liang, Deyuan Zhong, Hongtao Yan, Qinyan Yang, Xiaolun Huang
Article Number: 264
Published online on: 27 April 2026

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Computational discovery of novel colony‑stimulating factor‑1 receptor as a potential therapeutic biomarker in osteosarcoma and a novel inhibitor from herbal sources

Hui Zhang, Shiwei Wu, Dan Luo, Jincai Guo
Article Number: 263
Published online on: 24 April 2026

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Effect of the use of hormonal replacement therapy on breast cancer prognosis: A systematic review and meta‑analysis

Javier Angel Canelas Fernández, Jéssica Alonso‑Molero, Paz Rodríguez‑Cundín, Javier Llorca, Inés Gómez‑Acebo, Trinidad Dierssen‑Sotos
Article Number: 262
Published online on: 24 April 2026

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Evaluation of smoking status as a prognostic factor under immune checkpoint inhibitor treatment: A single center analysis

Christoph Schaefers, Annika Poch, Anika Forstreuter, Frederike Bokemeyer, Carsten Bokemeyer, Christoph Seidel
Article Number: 261
Published online on: 24 April 2026

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Correction Open Access

[Corrigendum] CDDO, a PPAR‑γ ligand, inhibits TPA‑induced cell migration and invasion through a PPAR‑γ‑independent mechanism

Hye-Yeon Jang, On-Yu Hong, Hyun Jo Youn, Jaeuk Jung, Eun Yong Chung, Sung Hoo Jung, Jong-Suk Kim
Article Number: 260
Published online on: 24 April 2026

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Review Open Access

Dual roles of neutrophil extracellular traps in tumors: From pro‑metastatic mechanisms to immunotherapeutic strategies (Review)

Mingxin Guo, Han Wang, Jiaqi Zeng, Ning Wu, Zhiqiang Hu, Ao Xue, Ting Dai
Article Number: 259
Published online on: 23 April 2026

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Review Open Access

Emerging role of protein arginine methyltransferase 5 in gastrointestinal cancer (Review)

Rui Zhang, Yiwen Lu, Xiaohua Fang, Fengquan Zhang, Weidong Wu, Jie Song, Zhenzhen Liang
Article Number: 258
Published online on: 23 April 2026

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Case Report Open Access

Adjuvant immunotherapy plus chemotherapy and maintenance immunotherapy for pulmonary lymphoepithelioma‑like carcinoma with hepatitis B virus infection, KRAS mutation and high expression of programmed death ligand 1: A case report

Jing Zhu, Qing-Gui Xu, Jiao Zhu, Rui-Xiang Zhou, Yu-Chuan Zhou, Zhi-Ke Li
Article Number: 257
Published online on: 22 April 2026

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Retraction Open Access

[Retracted] Interleukin‑17 promotes the development of cisplatin resistance in colorectal cancer

Guolong Sui, Yingna Qiu, Haijuan Yu, Qingbin Kong, Baowen Zhen
Article Number: 256
Published online on: 22 April 2026

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Article Open Access

An m6A‑programmed cell death signature predicts prognosis and identifies STK25 as a therapeutic target in colon adenocarcinoma

Hezhi Yu, Tihui Li, Xiaoyun Huang, Zihan Chen, Zixiang Lin, Fenglin Chen
Article Number: 255
Published online on: 22 April 2026

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Article Open Access

METTL5 reprograms glycolytic metabolism and promotes non‑small cell lung cancer progression by modifying PGAM1

Yuchen Shan, Xiaoyu Duan, Kai Yuan, Ming Lou, Qiyong Wu, Zhaojia Gao
Article Number: 254
Published online on: 20 April 2026

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Article Open Access

Clinical features and outcomes of peripheral T‑cell lymphoma, not otherwise specified: A single institution retrospective analysis of 30 cases

Meng-Xue Ma, Ya-Li Zhang, Li-Na Xing, Qiu-Yi Wang, Shukai Qiao
Article Number: 253
Published online on: 20 April 2026

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Article Open Access

BUD23 is associated with malignancy and correlates with immune infiltration in NSCLC

Yonghuang Tan, Jun Ma, Jiangli Zhou, Jianjun Lu
Article Number: 252
Published online on: 20 April 2026

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Article Open Access

Evaluation of NID2 and CDO1 methylation for ovarian cancer screening

Shuilian Wu, Jing Jin, Yuanyuan Cao, Xiaofan He, Qiang Hou, Mingfeng Jiang
Article Number: 251
Published online on: 20 April 2026

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Retraction Open Access

[Retracted] Improved ataxia telangiectasia mutated kinase inhibitor KU60019 provides a promising treatment strategy for non‑invasive breast cancer

Ying Zhu, Changfei Mao, Jianzhong Wu, Shuchun Li, Rong Ma, Haixia Cao, Minghua Ji, Changwen Jing, Jinhai Tang
Article Number: 250
Published online on: 20 April 2026

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Case Report Open Access

Fever and leukemoid reaction in bladder cancer: A case report

Tianrun Huang, Jiguo Xu, Yuwei He, Yu Shen, Chenlong Chu, Jingyuan Lu, Parehe Alimu, Chunlei Chen, Jianhe Liu
Article Number: 249
Published online on: 20 April 2026

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Article Open Access

Prognostic effect and prognostic factors of TACE for the treatment of unresectable hepatocellular carcinoma: Propensity score matching analysis

Liangliang Zhang, Cancan Li, Hui Guo, Xue Zhang, Wei Liu, Xing Xu
Article Number: 248
Published online on: 16 April 2026

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Expression of Concern Open Access

[Expression of Concern] Long non‑coding RNA BX357664 inhibits cell proliferation and metastasis in human lung cancer

Shu-Hui Xiao, Gong-Xiang Li, Lingli Quan
Article Number: 247
Published online on: 16 April 2026

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Article

Safety and feasibility of total neoadjuvant FLOT chemotherapy in locally‑advanced gastric and gastroesophageal junction cancer

Oleksii Dobrzhanskyi, Andrii Horodetskyi, Mykyta Pepenin, Yurii Kondratskyi
Article Number: 246
Published online on: 16 April 2026

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Article Open Access

Vasculogenic mimicry and breast cancer prognosis: Insights into predictive model development

Zhifeng Wu, Yueyue Teng, Shengchao Huang, Shiming Shi, Pu Qiu, Leyao Shan, Meihua Lin, Yuanqi Zhang
Article Number: 245
Published online on: 15 April 2026

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Effect and safety analysis of raltitrexed peritoneal perfusion in patients with intermediate and advanced colorectal cancer

Yanhua Wan, Xiaoyun Dai, Liang Chao
Article Number: 244
Published online on: 15 April 2026

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Article Open Access

Mechanism of action of alkaloids in Fritillaria‑induced autophagy and apoptosis in non‑small cell lung cancer

Mengru Teng, Mengrui Zhang, Jun He, Wai Ming Tse, Kathy Wai Gaun Tse, Chengwu Liu, Bengui Ye
Article Number: 243
Published online on: 15 April 2026

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Article Open Access

Identification of a prognostic model using immune related genes combined with tumour mutational burden and T cell infiltration in triple‑negative breast cancer

You Meng, Ze-Xin Han, Jie Zhu, Ying Wang, Yue-Qing Huang, Zhong-Hua Zou, Yu-Yuan Ma, Yi-Fan Li, Han Wang, Ying Li, Lian Lian, Wen-Jie Wang
Article Number: 242
Published online on: 15 April 2026

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Correction Open Access

[Corrigendum] Silencing glioma‑associated oncogene homolog 1 suppresses the migration and invasion of hepatocellular carcinoma in vitro

Zeming Hu, Fangfang Xie, Ang Hu, Mengjing Xu, Yuwen Liu, Jiankang Zhang, Jianbo Xiao, Yunlei Song, Jianing Zhong, Bin Chen
Article Number: 241
Published online on: 15 April 2026

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Article

A novel inflammation and tumor marker‑based prognostic score, neutrophil‑lymphocyte ratio‑C‑reactive protein‑Ca19‑9, in metastatic gastric cancer

Berkan Karabuğa, Osman Bilge Kaya, Ekin Konca Karabuğa, Ergin Aydemir, Mehmet Emin Yilmaz, Sedef Tatar Bolat, Ayşegül Uçkun, Enes Kaptan, Öztürk Ateş, Mustafa Büyükkör
Article Number: 240
Published online on: 15 April 2026

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Article Open Access

KRAS (G12D)‑selective inhibitor MRTX1133 suppresses proliferation and differentially modulates chemosensitivity in ovarian mucinous carcinoma

Ryota Watano, Hiroaki Mizukami, Yasushi Saga
Article Number: 239
Published online on: 15 April 2026

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Article

Intensity‑ and time‑dependent anticancer effects of alternating electric fields in non‑small cell lung cancer cell lines

Jinju Heo, Myonggeun Yoon
Article Number: 238
Published online on: 15 April 2026

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Review Open Access

KLF family of proteins in gastrointestinal tumors (Review)

Jingjing Zhang, Rupu Zhao, Pengjie Yang, Yong Zhu, Benben Zhu
Article Number: 237
Published online on: 15 April 2026

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Article

Establishment and validation of a diagnostic model for evaluating synchronous liver metastasis in pancreatic cancer using comprehensive blood biochemical indicators

Yiyi Jiang, Gaoyao Peng, Songqing He, Jiangfa Li
Article Number: 236
Published online on: 14 April 2026

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Review Open Access

Soluble isoforms of EGFR family in breast cancer: Advances and clinical relevance (Review)

Peng Yang, Xinnong Jiang, Fangguo He
Article Number: 235
Published online on: 14 April 2026

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Article Open Access

Thrombospondin‑1 triggers calreticulin expression in human mucoepidermoid carcinoma MC‑3 cells via the PERK/CHOP pathway

Shengwei Bao, Yuanyuan Zhu, Lijuan Guo, Sen Yang
Article Number: 234
Published online on: 14 April 2026

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Article Open Access

Unveiling the prognostic and immunotherapeutic role of Tregs in lung cancer using integrated analysis of single‑cell and bulk RNA‑sequencing

Hongwei He, Zhiming Xiao, Jijun Xue, Yu Zhang, Jichen Qu, Peng Wu, Qiangjun He
Article Number: 233
Published online on: 14 April 2026

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Review Open Access

Nobiletin in cancer therapy: Emerging insights into multi-target mechanisms, overcoming drug resistance and therapeutic translation (Review)

Yanfang Zhang, Qingcai Li, Wenbin Yu, Bin He, Jiahua Peng, Bin Yao
Article Number: 232
Published online on: 14 April 2026

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Expression of Concern Open Access

[Expression of Concern] Apoptotic effect of gambogic acid in esophageal squamous cell carcinoma cells via suppression of the NF‑κB pathway

Wen-Yue Liu, Xu Wu, Cheng-Quan Liao, Jie Shen, Jun Li
Article Number: 231
Published online on: 14 April 2026

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Article

Pretreatment C‑reactive protein‑triglyceride‑glucose index predicts survival in patients with FLOT‑treated locally advanced gastric and gastroesophageal junction cancer

Ayşegül Dumludağ, Mehmet Torun, Osman Sütçüoğlu
Article Number: 230
Published online on: 09 April 2026

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Case Report

Intravascular large B‑cell lymphoma mimicking an orbital mass lesion and bilateral cavernous sinus syndrome: A case report

Qiong Wu, Yiran Jia, Bentao Yang, Xiaojin He, Hongjuan Liu, Libin Jiang
Article Number: 229
Published online on: 09 April 2026

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Correction Open Access

[Corrigendum] FXR1 promotes proliferation, invasion and migration of hepatocellular carcinoma in vitro and in vivo

Kun Zhao, Jie Gao, Jihua Shi, Chengcheng Shi, Chun Pang, Jie Li, Wenzhi Guo, Shuijun Zhang
Article Number: 228
Published online on: 09 April 2026

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Article Open Access

Role of CDX2 in the prognosis of colorectal cancer across stages 0‑IV

Guojun Tong, Hai Qian, Yuefeng Fei, Sheng Yu, Kun Guo, Wenwen Yu, Jing Li, Sicheng Yan
Article Number: 227
Published online on: 08 April 2026

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Article Open Access

Exploring multiple biomarkers and constructing ferroptosis‑associated competing endogenous RNA networks as dual targets in retinoblastoma

Zhengjia Kang, Gaoqin Liu
Article Number: 226
Published online on: 08 April 2026

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Review Open Access

Role of mesenchymal stem cells and their derived exosomes in cervical cancer: Bidirectional mechanisms and research progress (Review)

Xue Li, Daqing Wang
Article Number: 225
Published online on: 08 April 2026

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Review Open Access

Hypoxia‑inducible factors: Regulatory functions and status as a therapeutic target in gastric cancer (Review)

Jia Xu, Guangzhi Ding, Yiming Wang, Chang Liu
Article Number: 224
Published online on: 08 April 2026

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Article Open Access

Machine learning‑based programmed cell death gene signature for prognosis and drug sensitivity in breast cancer

Nan Wu, Zhongting Fan
Article Number: 223
Published online on: 08 April 2026

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Article Open Access

Assessing the density of lymph node metastasis in various inguinal regions of penile cancer using the nine‑section method: A prospective study

Chen Hu, Longguo Dai, Hongyi Wu, Yu Bai, Jun Li, Haiyang Jiang, Haoli Yin, Ying Bi, Wenzhao Wu, Ruiqian Li, Hong Shi
Article Number: 222
Published online on: 08 April 2026

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Article Open Access

Overexpression and knockdown of 5‑lipoxygenase regulates the migration and invasion of colorectal cancer cells

Xuyang Li, Jiletu Huge, Xiaoling Wang, Jing Zhou, Xiudan Li, Xiaoyan Gao, Tiewei Shi, Chunying Bai
Article Number: 221
Published online on: 08 April 2026

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Case Report

Targeting TROP‑2 in treatment‑resistant non‑small cell lung cancer harboring the KRAS G12C mutation and TROP‑2 upregulation: A case report

Lu Sun, Ying Xiong, Xiaobing Li, Yi Peng
Article Number: 220
Published online on: 08 April 2026

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Article Open Access

Exosomal‑miR‑32‑5p directly targets FOXN2 to regulate the proliferation, migration and apoptosis of uterine corpus endometrial carcinoma via the PI3K/AKT/BCL‑2 pathway

Xin Chen, Huihui Li, Xiang Cheng, Yirong Cai, Guangyi Guo
Article Number: 219
Published online on: 08 April 2026

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Expression of Concern Open Access

[Expression of Concern] PRKACB is downregulated in non‑small cell lung cancer and exogenous PRKACB inhibits proliferation and invasion of LTEP‑A2 cells

Yong Chen, Ying Gao, Ye Tian, Da-Li Tian
Article Number: 218
Published online on: 07 April 2026

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Review Open Access

Lactylation enzymes in cancer: Mechanisms and novel therapeutic approaches (Review)

Guiyang Tang, Hanrong Zuo, Rou Long, Chaohui Zhang, Yufan Lv, Xinyu Luo, Jieya Qiu, Jianhong Zuo
Article Number: 217
Published online on: 02 April 2026

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Case Report Open Access

Comprehensive treatment for intracranial invasive sinonasal intestinal‑type adenocarcinoma with a focus on radiotherapy dosage and immunological combination therapy: A case report

Lianlian Yang, Qian Zhao, Fang Yi, Wenyan Guo, Qiongwen Zhang, Song Zhou, Dong Li, Zhihui Li
Article Number: 216
Published online on: 02 April 2026

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Review Open Access

Biological basis and clinical translation prospects of circulating cell‑free DNA in precision management of breast cancer (Review)

Li-Zhuang Fan, Ai-Lan Xu, Ya-Ru Xu, Luo Yang, Fang Yuan, Xin Nie
Article Number: 215
Published online on: 02 April 2026

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Review Open Access

Cutting‑edge advances in endocrine therapy for breast cancer (Review)

Yumei Dong, Lihua Shao, Qiong Li, Yuexiao Qi, Tingting Liu, Shihong Wei, Haiyan Qi
Article Number: 214
Published online on: 02 April 2026

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Case Report Open Access

Rapidly progressive squamous lung cancer with peripheral blood eosinophilia in a 25-year-old woman: A case report

Mingrui Zhang, Huanfang Fan, Chunxia Sun, Dehui Li, Jiangya Gan, Yun He, Jiaqi Chen
Article Number: 213
Published online on: 02 April 2026

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Article Open Access

Dynamic curve type serves as an effective tool for the diagnosis of benign or malignant non‑mass enhancements on breast MRI

Tara Farooq Kareem, Areege Mustafa Kamal, Munawar Al Nakash
Article Number: 212
Published online on: 02 April 2026

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Article Open Access

Clinical predictors of leptomeningeal metastasis from lung adenocarcinoma based on retrospective analysis

Yunyun Lu, Yi Lu, Yueyue Zhang, Hongyuan Du, Xuan Cao, Dexi Jin, Guofu Chen, Xiaohui Yang
Article Number: 211
Published online on: 01 April 2026

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Expression of Concern Open Access

[Expression of Concern] Delphinidin induces cell cycle arrest and apoptosis in HER‑2 positive breast cancer cell lines by regulating the NF‑κB and MAPK signaling pathways

Ailin Wu, Yanfeng Zhu, Bin Han, Jiayuan Peng, Xiaomin Deng, Wei Chen, Jingchang Du, Yu Ou, Xiaoli Peng, Xiaoping Yu
Article Number: 210
Published online on: 01 April 2026

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Case Report Open Access

Primary thoracic synovial sarcoma in a 45‑year‑old male: A case report and literature review

Baolei Liang, Jichun Zhang, Mingqiang Shen, Cuilian Li, Mingxiao Hou, Yunen Liu, Qingyong Cai
Article Number: 209
Published online on: 31 March 2026

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Expression of Concern Open Access

[Expression of Concern] Pseudomonas aeruginosa‑mannose‑sensitive hema-gglutinin inhibits proliferation and induces apoptosis in a caspase‑dependent manner in human bladder cancer cell lines

Yi-Ping Zhu, Xiao-Jie Bian, Ding-Wei Ye, Xu-Dong Yao, Shi-Lin Zhang, Bo Dai, Yi-Jun Shen
Article Number: 208
Published online on: 31 March 2026

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Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Decoding the role of polyamine metabolism in lung adenocarcinoma prognosis: A triangulated approach combining transcriptome, single‑cell and Mendelian randomization analyses

Hua Yang, Lemeng Zhang, Jianhua Chen, Junjie Zhang
Article Number: 310
Published online on: 21 May 2026

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Correction Open Access

[Corrigendum] Antitumor effects of dioscin in A431 cells via adjusting ATM/p53‑mediated cell apoptosis, DNA damage and migration

Peng Wang, Chun Wang, Chunying Liu
Article Number: 309
Published online on: 21 May 2026

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Review Open Access

Targeting non‑small cell lung cancer: Molecular mechanisms and clinical studies (Review)

Ying Luo, Guofang Yin, Xiaoqin Luo, Yue Liu, Kaiyu Jin, Zhiguo Wang
Article Number: 308
Published online on: 20 May 2026

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Article Open Access

Histopathological changes in primary extramammary Paget disease with emphasis on syringomatous structures and syringocystadenocarcinoma papilliferum in situ‑like changes

Yutaro Fukuma, Mitsuaki Ishida, Yoshinobu Hirose
Article Number: 307
Published online on: 20 May 2026

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Case Report Open Access

Durable response to selpercatinib in HOOK3‑RET fusion positive, α‑fetoprotein producing metastatic pancreatic ductal adenocarcinoma with intestinal‑type differentiation

Harsahib Singh Sandhu, Aparna Natarajan, Smiley Joshi
Article Number: 306
Published online on: 20 May 2026

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Correction Open Access

[Corrigendum] PVT1 promotes resistance to 5‑FU in colon cancer via the miR‑486‑5p/CDK4 axis

Zhuhe Luo, Ruijun Chen, Shen Hu, Xibin Huang, Zhenyi Huang
Article Number: 305
Published online on: 20 May 2026

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Case Report Open Access

Pelvic schwannoma misdiagnosed as colorectal cancer metastasis and the corresponding diagnostic lessons: A report of two cases

Shilong Wang, Kaixiang Zhang, Xiangwu Lin, Feilai Xie, Jian Yang, Jie Li
Article Number: 304
Published online on: 19 May 2026

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Case Report

Multidetector computed tomography detection of perineural infiltration around the superior mesenteric artery in intrahepatic cholangiocarcinoma: A case report

Myeong Hun Oh, Byeong Gwan Noh, Hyung Il Seo, Young Mok Park, Suk Kim, Nam Kyung Lee, Seung Baek Hong
Article Number: 303
Published online on: 19 May 2026

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Review Open Access

Clinical implications of lactylation modification in digestive system tumors (Review)

Lin Pan, Fengye Liu, Wenjing Yu
Article Number: 302
Published online on: 19 May 2026

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Article Open Access

Rare BRCA1 c.3418_3419insTGACTACT:p.S1140Mfs*18 germline mutation in a family with breast and ovarian cancer

Chao Zhai, Long Jia, Chaoyang Wang, Liang Chen, Tuo Han, Dong Xiao
Article Number: 301
Published online on: 19 May 2026

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Expression of Concern Open Access

[Expression of Concern] miR‑148a inhibits cell proliferation and migration through targeting ErbB3 in colorectal cancer

Wei Zhao, Jianbao Zheng, Guangbing Wei, Kui Yang, Guanghui Wang, Xuejun Sun
Article Number: 300
Published online on: 19 May 2026

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Article Open Access

Prognostic significance of squamous differentiation in pT2N0 urothelial bladder cancer

Alper Coskun, Ahmet Bilgehan Sahin, Selva Kabul, Mehmet Emin Dagtekin, Seda Sali, Buket Erkan Ozmarasali, Adem Deligonul, Erdem Cubukcu, Meral Kurt, Gursel Savci, Turkkan Evrensel, Ismet Yavascaoglu
Article Number: 299
Published online on: 18 May 2026

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Article

Jaceosidin inhibits cell viability and induces apoptosis in non‑small cell lung cancer by inhibiting the Ras/Raf/MEK/ERK and Akt pathways

Xiaodie Cao, Chong Ma, Xin Wang, Cui Wang, Lanlin Shen, Jingru Wei, Rongmin Yang, Yan Li, Xu He, Li Chen
Article Number: 298
Published online on: 18 May 2026

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Review Open Access

Ubiquitination and N6‑methyladenosine in cancer: Convergent regulation of oncogenic signaling pathways (Review)

Hailong Li, Xuelin Lu
Article Number: 297
Published online on: 18 May 2026

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Correction Open Access

[Corrigendum] TERT promoter regulating melittin expression induces apoptosis and G0/G1 cell cycle arrest in esophageal carcinoma cells

Chao Zhou, Jie Ma, Yuanhua Lu, Wan Zhao, Bingxue Xu, Jian Lin, Yongjun Ma, Yafei Tian, Qi Zhang, Wei Wang, Weiqun Yan, Ping Jiao
Article Number: 296
Published online on: 15 May 2026

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Case Report Open Access

Primary endometrioid adenocarcinoma of the vagina after total hysterectomy for adenomyosis: A case report

Tingting Wang, Xin Li, Liping Chen, Jing Zhang, Lina Peng, Haitao Yang
Article Number: 295
Published online on: 14 May 2026

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Correction Open Access

[Corrigendum] Tanshinol upregulates the expression of aquaporin 5 in lung tissue of rats with sepsis

Jianfeng Xu, Lei Yang, Liang Dong
Article Number: 294
Published online on: 14 May 2026

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Article Open Access

Weekly cisplatin and nab‑paclitaxel neoadjuvant chemoradiotherapy increases pathological complete response in locally advanced esophageal squamous cell carcinoma: A real‑world study

Li Li, Xuquan Jing, Jiling Niu, Yan Yi, Yujie Wang, Ke Zhao, Jingyu Luo, Jinming Yu, Hui Zhu
Article Number: 293
Published online on: 13 May 2026

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Article Open Access

Gastrointestinal cancer with indeterminate 18F‑FDG PET/CT findings: Diagnostic efficacy analysis of 68Ga‑FAPI‑04 PET/MRI

Jingxuan Miao, Yifei Xu, Feng Qiao, Ni Chen, Muhammad Imran Khan, Ye Zhao, Hui Wang
Article Number: 292
Published online on: 13 May 2026

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Article Open Access

Breaking senescence restriction: MAFK‑AREG axis promotes NSCLC cells to resist doxorubicin

Ningning Fan, Guanying Liang, Jiayue Shao, Qi Wang, Lu Fu
Article Number: 291
Published online on: 13 May 2026

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Expression of Concern Open Access

[Expression of Concern] Rap2B promotes the proliferation and migration of human glioma cells via activation of the ERK pathway

Guohong Shi, Zhen Zhang
Article Number: 290
Published online on: 11 May 2026

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Article Open Access

A novel prognostic biomarker combining TP53 loss‑of‑function and amplification of different combinations of nine genes in lung squamous cell carcinoma treated with chemotherapy

Yuli Li, Ting Hou, Hongjie Liu, Haiwei Du, Li Qiu, Yajing Zhang, Guiping Zhang, Yuan Tang
Article Number: 289
Published online on: 11 May 2026

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Article Open Access

Meta‑analysis of efficacy comparisons between standard‑ and low‑dose Bacillus Calmette‑Guerin vaccines in managing non‑muscular invasive bladder cancer

Xiaoxi Liu, Yige Bao
Article Number: 288
Published online on: 08 May 2026

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Correction Open Access

[Corrigendum] EGFR and ERK activation resists flavonoid quercetin‑induced anticancer activities in human cervical cancer cells in vitro

Xin Chen, Pengli Xu, Huijun Zhang, Xiaosan Su, Lihua Guo, Xuhong Zhou, Junliang Wang, Peng Huang, Qingzhi Zhang, Ruifen Sun
Article Number: 287
Published online on: 08 May 2026

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Article Open Access

Cumulative evidence for associations between matrix metalloproteinase‑1, ‑3 and ‑8 variants and cancer risk

Suqin Xu, Xianping Liu, Chenglu Huang
Article Number: 286
Published online on: 07 May 2026

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Article

PD‑1 inhibitors combined with tyrosine kinase inhibitor‑associated hypothyroidism is a predictive factor for antitumor effectiveness in male patients with hepatocellular carcinoma

Bailu Cao, Min Ai, Ping Huang, Huan Zhong
Article Number: 285
Published online on: 07 May 2026

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Correction Open Access

[Corrigendum] Proliferation, migration and invasion of triple negative breast cancer cells are suppressed by berbamine via the PI3K/Akt/MDM2/p53 and PI3K/Akt/mTOR signaling pathways

Lili Liu, Jiadong Yan, Ying Cao, Yan Yan, Xiang Shen, Binbin Yu, Li Tao, Shusheng Wang
Article Number: 284
Published online on: 06 May 2026

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Article Open Access

Evaluation of ct‑DNA and mutational status in liquid biopsy of patients with metastatic colorectal cancer

George Zarkavelis, Melina Yerolatsite, Panagiotis Ntellas, Aikaterini Tsantikidi, Irene Papadopoulou, Nanteznta Torounidou, Katerina Dadouli, George Nasioulas, Eleftherios Kampletsas, George Pentheroudakis
Article Number: 283
Published online on: 06 May 2026

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Article Open Access

Immunotherapy retreatment with serplulimab vs. chemotherapy in extensive‑stage advanced small cell lung cancer

Xinhang Gu, Xue Wu, Jiaxiao Geng, Yan Wang, Chengxin Liu
Article Number: 282
Published online on: 06 May 2026

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Article Open Access

Next‑generation sequencing elucidates the distinct mutational landscape of SMARCA4‑deficient lung cancer

Feicheng Yang, Yuzhong Yang, Zhihong Chen, Yanchun Li, Yinghui Song
Article Number: 281
Published online on: 05 May 2026

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Correction Open Access

[Corrigendum] Eupafolin inhibits breast cancer cell proliferation and induces apoptosis by inhibiting the PI3K/Akt/mTOR pathway

Jiahui Wei, Xuefeng Zhang, Huihao Pan, Song He, Bao Yuan, Qing Liu, Jiabao Zhang, Yu Ding
Article Number: 280
Published online on: 05 May 2026

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Article

Mutational landscape in the precancerous stages of sporadic colorectal cancer

Anna Valickova, Marketa Urbanova, Josef Horak, Jiri Jungwirth, Jan Kral, Tomas Hucl, Veronika Makajevova, Sandra Summerova, Pavel Kohout, Radoslav Matej, Pavel Vodicka, Veronika Vymetalkova
Article Number: 279
Published online on: 04 May 2026

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Article Open Access

Comparing the efficacy of immune checkpoint inhibitors with and without microwave ablation in advanced hepatocellular carcinoma in real‑world clinical practice: A retrospective cohort study

Chun Wei, Sizhong Chen, Li Ding, Ting Zhou, Fan Huang, Yong Wang, Ou Jiang, Yu Liu
Article Number: 278
Published online on: 04 May 2026

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Expression of Concern Open Access

[Expression of Concern] FHOD1 is upregulated in gastric cancer and promotes the proliferation and invasion of gastric cancer cells

Chengfei Jiang, Binbin Yuan, Bo Hang, Jian-Hua Mao, Xiaoping Zou, Pin Wang
Article Number: 277
Published online on: 29 April 2026

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Review Open Access

Watch‑and‑wait in rectal cancer: A critical appraisal of promise, perils and unresolved contours of organ preservation (Review)

Xinqiang Zhu, Beibei Ge, Linchun Wen, Siwei Shan
Article Number: 276
Published online on: 28 April 2026

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Review Open Access

Multi‑omics profiling of pancreatic neuroendocrine tumors: Interplay of genomic instability and the tumor microenvironment (Review)

Yin Wan, Yingnan Zhang, Philip A. Philip, Herbert Chen, Bassel El‑Rayes, Asfar S. Azmi, Yang Shi
Article Number: 275
Published online on: 28 April 2026

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Article Open Access

SOX2‑positive upper tract urothelial carcinoma: Clinicopathological characteristics and therapeutic implications

Hitomi Yasukawa, Yoshinori Ikehata, Naotaka Nishiyama, Hiroshi Kitamura
Article Number: 274
Published online on: 28 April 2026

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Case Report Open Access

Diagnostic and therapeutic challenges of locally advanced colon cancer complicated with acute lymphoblastic leukemia: A case report

Yuping Zeng, Song Mu, Guosheng Li, Zhengzi Liang, Qinghua Ji, Yunhuan Zhen, Wenling Wang, Weiwei Chen
Article Number: 273
Published online on: 28 April 2026

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Article Open Access

LINC00184 promotes esophageal squamous cell carcinoma progression via DNMT1‑mediated methylation of the NDRG2 promoter and PI3K/AKT pathway activation

Junjun Guo, Shenbo Fu, Jia Liu, Lina Li, Jin Zhao, Fenggang Wang, Wenan Wu, Xu Chen, Enxiao Li
Article Number: 272
Published online on: 28 April 2026

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Case Report Open Access

A clear cell sarcoma tumor of the finger with an unusual presentation misdiagnosed as a glomus tumor in an adolescent patient: A case report

Abdulrahman Alaseem, Hatim Khoja, Khalid Murrad, Sarah Alkhalife, Nouf Altwaijri, Abdullah Almawi, Abdulaziz Bin Dakhil, Abdulaziz Alhammad, Banan Alqady, Eman Najjar
Article Number: 271
Published online on: 28 April 2026

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Case Report Open Access

Primary thyroid lymphoma with Hashimoto's thyroiditis: A case report and literature review

Fangshu Liu, Xueya Xin, Kai Tan, Xinv Chen, Chanjuan Shen, Qiuhong Yang
Article Number: 270
Published online on: 28 April 2026

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Expression of Concern Open Access

[Expression of Concern] In vitro and in vivo inhibition of tumor cell viability by combined dihydroartemisinin and doxorubicin treatment, and the underlying mechanism

Xiang Tai, Xiao-Bei Cai, Zhang Zhang, Rui Wei
Article Number: 269
Published online on: 28 April 2026

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