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Case Report

Fatal pneumonitis associated with postoperative intensity-modulated radiotherapy in lung cancer: Case report and review

  • Authors:
    • Yan Hu
    • Jingjing Li
    • Xiaoyan Su
  • View Affiliations / Copyright

    Affiliations: Department of Oncology, The First People's Hospital of Jingzhou, Jingzhou, Hubei 434000, P.R. China
  • Pages: 714-716
    |
    Published online on: November 30, 2012
       https://doi.org/10.3892/ol.2012.1053
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Abstract

Radiation pneumonitis (RP) is the most significant complication of acute treatment-related toxicities in lung cancer. Intensity-modulated radiotherapy (IMRT) with inverse planning enables us to achieve the desired dose distribution. However, there are many high-risk procedures associated with lung irradiation, including chemotherapy and surgery. We report a case of fatal treatment-related pneumonitis, where the patient had undergone postoperative IMRT for lung cancer. Following completion of radiotherapy, the patient developed progressive dyspnea. A chest computed tomography (CT) scan revealed the presence of diffuse reticular interstitial processes and honeycombing in both lungs. The fibrotic change in both lungs in a transverse view was compatible with low-dose irradiation of non-target organs at risk. Acute radiation pneumonitis was diagnosed. For patients receiving postoperative IMRT, low-dose irradiation volumes should be considered for lungs, as well as strict dose-volume histogram (DVH) parameters.
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Copy and paste a formatted citation
Spandidos Publications style
Hu Y, Li J and Su X: Fatal pneumonitis associated with postoperative intensity-modulated radiotherapy in lung cancer: Case report and review. Oncol Lett 5: 714-716, 2013.
APA
Hu, Y., Li, J., & Su, X. (2013). Fatal pneumonitis associated with postoperative intensity-modulated radiotherapy in lung cancer: Case report and review. Oncology Letters, 5, 714-716. https://doi.org/10.3892/ol.2012.1053
MLA
Hu, Y., Li, J., Su, X."Fatal pneumonitis associated with postoperative intensity-modulated radiotherapy in lung cancer: Case report and review". Oncology Letters 5.2 (2013): 714-716.
Chicago
Hu, Y., Li, J., Su, X."Fatal pneumonitis associated with postoperative intensity-modulated radiotherapy in lung cancer: Case report and review". Oncology Letters 5, no. 2 (2013): 714-716. https://doi.org/10.3892/ol.2012.1053
Copy and paste a formatted citation
x
Spandidos Publications style
Hu Y, Li J and Su X: Fatal pneumonitis associated with postoperative intensity-modulated radiotherapy in lung cancer: Case report and review. Oncol Lett 5: 714-716, 2013.
APA
Hu, Y., Li, J., & Su, X. (2013). Fatal pneumonitis associated with postoperative intensity-modulated radiotherapy in lung cancer: Case report and review. Oncology Letters, 5, 714-716. https://doi.org/10.3892/ol.2012.1053
MLA
Hu, Y., Li, J., Su, X."Fatal pneumonitis associated with postoperative intensity-modulated radiotherapy in lung cancer: Case report and review". Oncology Letters 5.2 (2013): 714-716.
Chicago
Hu, Y., Li, J., Su, X."Fatal pneumonitis associated with postoperative intensity-modulated radiotherapy in lung cancer: Case report and review". Oncology Letters 5, no. 2 (2013): 714-716. https://doi.org/10.3892/ol.2012.1053
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