Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Oncology Letters
Join Editorial Board Propose a Special Issue
Print ISSN: 1792-1074 Online ISSN: 1792-1082
Journal Cover
March 2013 Volume 5 Issue 3

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
March 2013 Volume 5 Issue 3

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Case Report

Use of panitumumab in the treatment of acinar cell carcinoma of the pancreas: A case report

  • Authors:
    • Manuel Morales
    • Miguel Ángel Cabrera
    • Maria Del Carmen Maeso
    • Noemí Ferrer-López
  • View Affiliations / Copyright

    Affiliations: Service of Medical Oncology, University Hospital Nuestra Señora de Candelaria, Santa Cruz de Tenerife, Canary Islands 38010, Spain, Service of Pathology, University Hospital Nuestra Señora de Candelaria, Santa Cruz de Tenerife, Canary Islands 38010, Spain
  • Pages: 969-971
    |
    Published online on: December 18, 2012
       https://doi.org/10.3892/ol.2012.1083
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

Two cases of stage IV acinar carcinoma of the pancreas are presented. The two patients were treated with several lines of chemotherapies active against colon cancer. At last‑line, both patients received panitumumab monotherapy. We describe the tumour response to the different therapies. Our findings demonstrate that panitumumab produces objective responses when used as third-line treatment in the therapy of patients with acinar cell carcinoma of the pancreas. Thus, we propose the consideration of the use of panitumumab in early lines of treatment.
View Figures

Figure 1

Figure 2

Figure 3

View References

1 

Distler M, Rückert F, Dittert DD, et al: Curative resection of a primarily unresectable acinar cell carcinoma of the pancreas after chemotherapy. World J Surg Oncol. 7:222009. View Article : Google Scholar : PubMed/NCBI

2 

Ohori NP, Khalid A, Etemad B and Finkelstein SD: Multiple loss of heterozygosity without K-ras mutation identified by molecular analysis on fine-needle aspiration cytology specimen of acinar cell carcinoma of pancreas. Diagn Cytopathol. 27:42–46. 2002. View Article : Google Scholar : PubMed/NCBI

3 

De la O JP and Murtaugh LC: Notch and Kras in pancreatic cancer: at the crossroads of mutation, differentiation and signalling. Cell Cycle. 8:1860–1864. 2009.PubMed/NCBI

4 

Royal RE, Wolff RA and Crane CH: Pancreatic cancer. CANCER: Principles & Practice of Oncology. DeVita V, Lawrence TS and Rosenberg SA: Wolter Kluver/Lippincott Williams & Wilkins; Philadelphia: pp. 1086–1123. 2008

5 

Abraham SC, Wu TT, Hruban RH, Lee JH, Yeo CJ, Conlon K, et al: Genetic and immunohistochemical analysis of pancreatic acinar cell carcinoma. Frequent allelic loss on chromosome 11p and alterations in the APC/beta catenin pathway. Am J Pathol. 160:953–962. 2002. View Article : Google Scholar : PubMed/NCBI

6 

Holen KD, Klimstra DS, Hummer A, et al: Clinical characteristics and outcomes from an institutional series of acinar cell carcinoma of the pancreas and related tumors. J Clin Oncol. 20:4673–4678. 2002. View Article : Google Scholar : PubMed/NCBI

7 

Schmidt CM, Matos JM, Bentrem DJ, Talamonti MS, Lillemoe KD and Bilimoria KY: Acinar cell carcinoma of the pancreas in the United States: prognostic factors and comparison to ductal adenocarcinoma. J Gastrointest Surg. 12:2078–2086. 2008. View Article : Google Scholar : PubMed/NCBI

8 

Antoine M, Khitrik-Palchuk M and Saif MW: Long-term survival in a patient with acinar cell carcinoma of pancreas. A case report and review of literature. JOP. 8:783–789. 2007.PubMed/NCBI

9 

Dewald GW, Smyrk TC, Thorland EC, et al: Fluorescence in situ hybridization to visualize genetic abnormalities in interphase cells of acinar cell carcinoma, ductal adenocarcinoma and islet cell carcinoma of the pancreas. Mayo Clin Proc. 84:801–810. 2009. View Article : Google Scholar

10 

Van Custem E, Peeters M, Siena S, et al: Open-label phase III trial of panitumumab plus best supportive care compared with best supportive care alone in patients with chemotherapy-refractory metastatic colorectal cancer. J Clin Oncol. 25:1658–1664. 2007.PubMed/NCBI

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Morales M, Cabrera MÁ, Del Carmen Maeso M and Ferrer-López N: Use of panitumumab in the treatment of acinar cell carcinoma of the pancreas: A case report . Oncol Lett 5: 969-971, 2013.
APA
Morales, M., Cabrera, M.Á., Del Carmen Maeso, M., & Ferrer-López, N. (2013). Use of panitumumab in the treatment of acinar cell carcinoma of the pancreas: A case report . Oncology Letters, 5, 969-971. https://doi.org/10.3892/ol.2012.1083
MLA
Morales, M., Cabrera, M. Á., Del Carmen Maeso, M., Ferrer-López, N."Use of panitumumab in the treatment of acinar cell carcinoma of the pancreas: A case report ". Oncology Letters 5.3 (2013): 969-971.
Chicago
Morales, M., Cabrera, M. Á., Del Carmen Maeso, M., Ferrer-López, N."Use of panitumumab in the treatment of acinar cell carcinoma of the pancreas: A case report ". Oncology Letters 5, no. 3 (2013): 969-971. https://doi.org/10.3892/ol.2012.1083
Copy and paste a formatted citation
x
Spandidos Publications style
Morales M, Cabrera MÁ, Del Carmen Maeso M and Ferrer-López N: Use of panitumumab in the treatment of acinar cell carcinoma of the pancreas: A case report . Oncol Lett 5: 969-971, 2013.
APA
Morales, M., Cabrera, M.Á., Del Carmen Maeso, M., & Ferrer-López, N. (2013). Use of panitumumab in the treatment of acinar cell carcinoma of the pancreas: A case report . Oncology Letters, 5, 969-971. https://doi.org/10.3892/ol.2012.1083
MLA
Morales, M., Cabrera, M. Á., Del Carmen Maeso, M., Ferrer-López, N."Use of panitumumab in the treatment of acinar cell carcinoma of the pancreas: A case report ". Oncology Letters 5.3 (2013): 969-971.
Chicago
Morales, M., Cabrera, M. Á., Del Carmen Maeso, M., Ferrer-López, N."Use of panitumumab in the treatment of acinar cell carcinoma of the pancreas: A case report ". Oncology Letters 5, no. 3 (2013): 969-971. https://doi.org/10.3892/ol.2012.1083
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team