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Oncology Letters
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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
March 2013 Volume 5 Issue 3

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Journal Metrics

Impact Factor: 2.2

CiteScore: 3.7

CiteScore Rank: Q3: #233/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Review

PAX8 is a novel marker for differentiating between various types of tumor, particularly ovarian epithelial carcinomas (Review)

Li Xiang, Beihua Kong
Pages: 735-738
Published online on: 10 January 2013

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Case Report

Undifferentiated embryonal sarcoma of the liver in a child: A case report and review of the literature

Jie Gao, Liming Fei, Sheng Li, Kai Cui, Jianbo Zhang, Fachang Yu, Bo Zhang
Pages: 739-742
Published online on: 19 December 2012

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Article

Completion lobectomy and central compartment dissection in low-risk patients who had undergone less extensive surgery than hemithyroidectomy

Wen-Bin Yu, Yun-Tao Song, Nai-Song Zhang
Pages: 743-748
Published online on: 28 December 2012

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Article

SMC1A knockdown induces growth suppression of human lung adenocarcinoma cells through G1/S cell cycle phase arrest and apoptosis pathways in vitro

Yi-Fan Zhang, Rui Jiang, Jin-Dong Li, Xing-Yi Zhang, Peng Zhao, Miao He, Hou-Zhong Zhang, Li-Ping Sun, Dong-Lei Shi, Guang-Xin Zhang, Mei Sun
Pages: 749-755
Published online on: 08 January 2013

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Article

Regulation of AKT gene expression by cisplatin

Jun Zhang, Ling‑Li Zhang, Lei Shen, Xi-Ming Xu, Hong‑Gang Yu
Pages: 756-760
Published online on: 14 January 2013

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Article

Comparative analysis of carboplatin and paclitaxel combination chemotherapy schedules in previously untreated patients with advanced non-small cell lung cancer

Toshiki Shimizu, Takashi Yokoi, Takeshi Tamaki, Kayoko Kibata, Noriko Inagaki, Shosaku Nomura
Pages: 761-767
Published online on: 15 January 2013

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Article

Comparison of immunohistology using pan-CK and EMA in the diagnosis of lymph node metastasis of gastric cancer, particularly micrometastasis and isolated tumor cells

Yi Yang, Junwei Li, Shanhua Mao, Hongguang Zhu
Pages: 768-772
Published online on: 14 December 2012

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Article

Sunlight may increase the FDG uptake value in primary tumors of patients with non-small cell lung cancer

Hasan Mutlu, Abdullah Büyükçelik, Eser Kaya, Mustafa Kibar, Ertuğrul Seyrek, Sinan Yavuz, Züleyha Çalıkuşu
Pages: 773-776
Published online on: 07 January 2013

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Article

In vivo evaluation of the synthesized novel 2-benzyloxybenzaldehyde analog CCY-1a-E2 for the treatment of leukemia in the BALB/c mouse WEHI-3 allograft model

Chingju Lin, Jai-Sing Yang, Shih-Chang Tsai, Chin-Fen Lin, Miau-Rong Lee
Pages: 777-782
Published online on: 17 December 2012

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Article

Prevalence of hepatitis B and C in patients with meningiomas and glioblastoma multiforme

Marc B. Cabanne, Quang D. Ma, Lillian Mecum, Rahul Jandial, Javed Siddiqi, Mike Y. Chen
Pages: 783-786
Published online on: 10 January 2013

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Article

Isolation and enrichment of PC-3 prostate cancer stem-like cells using MACS and serum-free medium

Xia Sheng, Zeng Li, De-Lin Wang, Wen-Bin Li, Zhao Luo, Ke-Hong Chen, Jian-Jia Cao, Chao Yu, Wu-Jiang Liu
Pages: 787-792
Published online on: 21 December 2012

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Case Report

A useful treatment for patients with advanced mixed-type small cell neuroendocrine carcinoma of the prostate: A case report

Kei-Ichiro Uemura, Go Nakagawa, Katsuaki Chikui, Fukuko Moriya, Makoto Nakiri, Tokumasa Hayashi, Shigetaka Suekane, Kei Matsuoka
Pages: 793-796
Published online on: 15 January 2013

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Article

Clinicopathological implications of leptin and leptin receptor expression in papillary thyroid cancer

Guo-An Zhang, Sen Hou, Sha Han, Jian Zhou, Xu Wang, Wen Cui
Pages: 797-800
Published online on: 10 January 2013

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Article

Effects of tubeimoside‑1 on the proliferation and apoptosis of BGC823 gastric cancer cells in vitro

Yi Zhang, Xiao-Man Xu, Meng Zhang, Dan Qu, Hui-Yan Niu, Xue Bai, Liang Kan, Ping He
Pages: 801-804
Published online on: 08 January 2013

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Article

Silencing of B7-H3 increases gemcitabine sensitivity by promoting apoptosis in pancreatic carcinoma

Xin Zhao, Guang-Bo Zhang, Wen-Juan Gan, Feng Xiong, Zhi Li, Hua Zhao, Dong-Ming Zhu, Bin Zhang, Xue-Guang Zhang, De-Chun Li
Pages: 805-812
Published online on: 08 January 2013

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Article

Expression of carboxyl terminus of Hsp70‑interacting protein (CHIP) indicates poor prognosis in human gallbladder carcinoma

Zhe Long Liang, Meeran Kim, Song Mei Huang, Hyo Jin Lee, Jin‑Man Kim
Pages: 813-818
Published online on: 15 January 2013

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Article

Serum response factor is overexpressed in esophageal squamous cell carcinoma and promotes Eca-109 cell proliferation and invasion

Xi He, Hong Xu, Min Zhao, Shijie Wang
Pages: 819-824
Published online on: 09 January 2013

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Case Report

Ureteral obstruction and urinary fistula due to fibrin glue after partial nephrectomy: A case report and review of the literature

Chao-Jun Wang, De-Bo Kong, Bai-Hua Shen, Shuo Wang, Bai-Ye Jin, Li-Ping Xie, Zhao-Dian Chen
Pages: 825-828
Published online on: 07 January 2013

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Article

microRNA-125b inhibits cell migration and invasion by targeting matrix metallopeptidase 13 in bladder cancer Retraction in /10.3892/ol.2022.13509

Deyao Wu, Jingjing Ding, Linmao Wang, Huixing Pan, Zhengdong Zhou, Jian Zhou, Ping Qu
Pages: 829-834
Published online on: 10 January 2013

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Article

Expression of steroid and xenobiotic receptor in uterine carcinosarcoma, leiomyosarcoma and endometrial stromal sarcoma

Xiaoni Yue, Hiroki Utsunomiya, Jun-Ichi Akahira, Fumihiko Suzuki, Kiyoshi Ito, Satoru Nagase, Hironobu Sasano, Nobuo Yaegashi
Pages: 835-839
Published online on: 28 December 2012

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Article

Intensity-modulated stereotactic body radiotherapy for stage I non-small cell lung cancer

Min-Jeong Kim, Seung-Gu Yeo, Eun Seok Kim, Chul Kee Min, Pyung Se An
Pages: 840-844
Published online on: 18 December 2012

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Article

Overexpression of the Notch3 receptor and its ligand Jagged1 in human clinically non-functioning pituitary adenomas

Runchun Lu, Hua Gao, Hongyun Wang, Lei Cao, Jiwei Bai, Yazhuo Zhang
Pages: 845-851
Published online on: 07 January 2013

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Article

Effect of thalidomide on the expression of vascular endothelial growth factor in a rat model of liver regeneration

Kuo-Chen Hung, Pei-Min Hsieh, Kun-Lin Yang, Kai-Jen Lin, Yaw-Sen Chen, Chih-Hsin Hung
Pages: 852-856
Published online on: 20 December 2012

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Article

TWIST interacts with endothelin-1/endothelin A receptor signaling in osteosarcoma cell survival against cisplatin

Yong Zhou, Xiaofang Zang, Zufa Huang, Chaoyue Zhang
Pages: 857-861
Published online on: 07 January 2013

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Case Report

Primary mediastinal myelolipoma: A case report and review of the literature

Chuanying Geng, Nian Liu, Guangzhong Yang, Man Qi, Wengming Chen
Pages: 862-864
Published online on: 19 December 2012

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Article

Expression and localization of TASK-1, -2 and -3 channels in MG63 human osteoblast-like cells

Xiantao Li, Xuehai Dong, Shouchao Zheng, Jun Xiao
Pages: 865-869
Published online on: 20 December 2012

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Article

Expression of the cannabinoid type I receptor and prognosis following surgery in colorectal cancer

Chan Kwon Jung, Won Kyung Kang, Jae Myung Park, Hyo Jun Ahn, Sang Woo Kim, Seong Taek Oh, Kyu Yong Choi
Pages: 870-876
Published online on: 18 December 2012

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Article

Characterization of side population cells isolated from the gastric cancer cell line SGC-7901

Rong Li, Xiaoling Wu, Huang Wei, Shangkun Tian
Pages: 877-883
Published online on: 02 January 2013

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Article

Overexpression of high mobility group box 1 and 2 is associated with the progression and angiogenesis of human bladder carcinoma

Wei Wang, Haowen Jiang, Hechen Zhu, Hu Zhang, Jian Gong, Limin Zhang, Qiang Ding
Pages: 884-888
Published online on: 27 December 2012

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Article

Phase I/II study of induction chemotherapy plus concurrent chemotherapy and SMART-IMRT-based radiotherapy in locoregionally-advanced nasopharyngeal cancer

Ting-Yong Fan, Jun Xing, Jie Lu, Tong-Hai Liu, Min Xu, Ying‑Jie  Zhang, Qian Shao, Jian-Bin Li, Jin-Ming Yu
Pages: 889-895
Published online on: 15 January 2013

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Article

Upregulated expression of LOX is a novel independent prognostic marker of worse outcome in gastric cancer patients after curative surgery

Qing Zhang, Xiao-Shun Jin, Zhong-Yin Yang, Min Wei, Xiao‑Cheng Zhu, Ping Wang, Bing-Ya Liu, Qin-Long Gu
Pages: 896-902
Published online on: 27 December 2012

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Article

Correlation among 16 biological factors [p53, p21waf1, MIB‑1 (Ki‑67), p16INK4A, cyclin D1, E‑cadherin, Bcl‑2, TNF‑α, NF‑κB, TGF‑β, MMP‑7, COX‑2, EGFR, HER2/neu, ER, and HIF‑1α] and clinical outcomes following curative chemoradiation therapy in 10 patients with esophageal squamous cell carcinoma

Shino Shibata‑Kobayashi, Hideomi Yamashita, Kae Okuma, Kenshiro Shiraishi, Hiroshi Igaki, Kuni Ohtomo, Keiichi Nakagawa
Pages: 903-910
Published online on: 11 January 2013

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Article

Cobalt chloride inhibits tumor formation in osteosarcoma cells through upregulation of HIF-1α

Bo Zhang, Weichun Guo, Ling Yu, Fu'an Wang, Yong Xu, Yang Liu, Chengxiao Huang
Pages: 911-916
Published online on: 10 January 2013

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Article

Studies on the anti‑angiogenic effect of Marsdenia tenacissima extract in vitro and in vivo

Zhengrong Huang, Hao Lin, Yong Wang, Zhiyun Cao, Wei Lin, Qiang Chen
Pages: 917-922
Published online on: 04 January 2013

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Article

Effects of combining Taxol and cyclooxygenase inhibitors on the angiogenesis and apoptosis in human ovarian cancer xenografts

Wei Li, Yun-Xian Tang, Liang Wan, Jia-Hui Cai, Jun Zhang
Pages: 923-928
Published online on: 19 December 2012

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Article

Regulation of the FOXO3a/Bim signaling pathway by 5,7-dihydroxy-8-nitrochrysin in MDA-MB-453 breast cancer cells

Xiao-Chun Zhao, Xiao-Cheng Cao, Fei Liu, Mei-Fang Quan, Kai-Qun Ren, Jian-Guo Cao
Pages: 929-934
Published online on: 14 December 2012

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Article

The effects of ERCC1 expression levels on the chemosensitivity of gastric cancer cells to platinum agents and survival in gastric cancer patients treated with oxaliplatin‑based adjuvant chemotherapy

Yong-Ping Liu, Yang Ling, Qiu-Feng Qi, Ya-Ping Zhang, Chang‑Song Zhang, Chang-Tai Zhu, Mei-Hua Wang, Yao-Dong Pan
Pages: 935-942
Published online on: 28 December 2012

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Article

Glioma in the third trimester of pregnancy: Two cases and a review of the literature

Jie Wu, Yan-Hui Ma, Tian-Long Wang
Pages: 943-946
Published online on: 04 January 2013

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Article

The effect of hydroxycamptothecin and pingyangmycin on human squamous cell carcinoma of the tongue

Peng Chen, Bing Liu, Ming Hu
Pages: 947-952
Published online on: 07 January 2013

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Article

Induction of cytokines and growth factors by rapamycin in the microenvironment of brain metastases of lung cancer

Se Hoon Kim, Jung Eun Lee, Seung-Ho Yang, Sang Won Lee
Pages: 953-958
Published online on: 15 January 2013

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Article

Arg399Gln polymorphism of XRCC1 gene and risk of colorectal cancer in Kashmir: A case control study

Saniya Nissar, Tufail Ahmad Lone, Mujeeb Zafar Banday, Roohi Rasool, Nissar A. Chowdri, Fazl Q. Parray, Safiya Abdullah, Aga Syed Sameer
Pages: 959-963
Published online on: 03 January 2013

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Article

Validity of the cohort of Crete in the Seven Countries Study: A time-series study applied to the cancer mortality trend between 1960 and 2011

Christos M. Hatzis, Dimitra Sifaki-Pistolla, Christopher Papandreou, Gregory I. Chlouverakis, Anthony G. Kafatos, Nikolaos E. Tzanakis
Pages: 964-968
Published online on: 14 January 2013

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Case Report

Use of panitumumab in the treatment of acinar cell carcinoma of the pancreas: A case report

Manuel Morales, Miguel Ángel Cabrera, Maria Del Carmen Maeso, Noemí Ferrer-López
Pages: 969-971
Published online on: 18 December 2012

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Article

Continuous morphine infusion for end-stage lung cancer patients

Young Hak Kim, Chiyuki Okuda, Yuichi Sakamori, Katsuhiro Masago, Yosuke Togashi, Michiaki Mishima
Pages: 972-974
Published online on: 28 December 2012

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Article

Rapid long-lasting biochemical and radiological response to sorafenib in a case of advanced hepatocellular carcinoma

Assunta Maria Teresa Gerardi, Luca Pio Stoppino, Arcangelo Liso, Luca Macarini, Matteo Landriscina
Pages: 975-977
Published online on: 11 January 2013

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Article

Five-point scoring system based on clinicopathological data: A convenient criterion to determine prognosis of patients with colorectal carcinoma

Tadahiro Nozoe, Mayuko Kohno, Tomohiro Iguchi, Takashi Maeda , Takahiro Ezaki
Pages: 978-982
Published online on: 08 January 2013

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Article

Platinum‑based chemotherapy in triple‑negative breast cancer: A meta‑analysis

Miao Liu, Qin‑Guo Mo, Chang‑Yuan Wei, Qing‑Hong Qin, Zhen Huang, Jie He
Pages: 983-991
Published online on: 28 December 2012

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Case Report

Primary spinal glioblastoma: A case report and review of the literature

Nuno Morais, Lino Mascarenhas, J. P. Soares-Fernandes, Ana  Silva, Zita Magalhães, J. A. Moreira Da Costa
Pages: 992-996
Published online on: 14 December 2012

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Case Report

Metastasis to the parotid region as an initial presentation of renal cell carcinoma: A case report

Chai Yanlan, Song Liping, Che Shaomin, Liu Zi
Pages: 997-999
Published online on: 07 January 2013

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Article

Differential expression of RBM5 and KRAS in pancreatic ductal adenocarcinoma and their association with clinicopathological features

Jie Peng, Ali Kord Valeshabad, Qingfu Li, Yuan Wang
Pages: 1000-1004
Published online on: 17 December 2012

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Article

Embelin-induced MCF-7 breast cancer cell apoptosis and blockade of MCF-7 cells in the G2/M phasevia the mitochondrial pathway

Yang Li, Dalei Li, Shengguang Yuan, Zhenran Wang, Fang Tang, Rongrong Nie, Jun Weng, Lina Ma, Bo Tang
Pages: 1005-1009
Published online on: 19 December 2012

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Article

Inhibition of cancer cell proliferation by midazolam by targeting transient receptor potential melastatin 7

Yunling Dou, Yuan Li, Jingkao Chen, Sihan Wu, Xiao Xiao, Shanshan Xie, Lipeng Tang, Min Yan, Youqiong Wang, Jun Lin, Wenbo Zhu, Guangmei Yan
Pages: 1010-1016
Published online on: 11 January 2013

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Article

Multiple carcinosarcomas of the esophagus and stomach

Feng Xu, Wen‑Bin Zou, Xiao‑Ping Li, Yue‑Mei Xu, Xu‑Fei Qi, Liang‑Hao Hu, Zhao-Shen Li, Ding‑Kang Yao
Pages: 1017-1021
Published online on: 28 December 2012

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Article

Microsomal epoxide hydrolase gene polymorphisms and risk of chronic obstructive pulmonary disease: A comprehensive meta‑analysis

Hui Li, Wei‑Ping Fu, Ze‑Hui Hong
Pages: 1022-1030
Published online on: 28 December 2012

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Article

RNA interference-mediated silencing of VEGF and bFGF suppresses endostatin secretion in pancreatic carcinoma cells

Changqing Yan, Chuan Wang, Mei Dong, Sanguang Liu, Cheng Qi, Yupei Zhao
Pages: 1031-1035
Published online on: 02 January 2013

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Article

Cassia tora L. (Jue‑ming‑zi) has anticancer activity in TCA8113 cells in vitro and exerts anti‑metastatic effects in vivo

Xin Zhao, Qiang Wang, Yu Qian, Liang Pang
Pages: 1036-1042
Published online on: 28 December 2012

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Article

Epithelial‑mesenchymal transition mediates anoikis resistance and enhances invasion in pleural effusion‑derived human lung cancer cells

Preedakorn Chunhacha, Virote Sriuranpong, Pithi Chanvorachote
Pages: 1043-1047
Published online on: 07 January 2013

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Article

Migration of gastric cancer cells in response to lysophosphatidic acid is mediated by LPA receptor 2

Dezhi Yang, Wenhua Yang, Qian Zhang, Yan Hu, Liang Bao, Alatangaole Damirin
Pages: 1048-1052
Published online on: 07 January 2013

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Article

GSTP1 negatively regulates Stat3 activation in epidermal growth factor signaling

Xianjuan Kou, Ning Chen, Zhiyong Feng, Lan Luo, Zhimin Yin
Pages: 1053-1057
Published online on: 28 December 2012

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Article

Downregulation of vasohibin-2, a novel angiogenesis regulator, suppresses tumor growth by inhibiting angiogenesis in endometrial cancer cells

Takahiro Koyanagi, Yasushi Saga, Yoshifumi Takahashi, Yasuhiro Suzuki, Mitsuaki Suzuki, Yasufumi Sato
Pages: 1058-1062
Published online on: 08 January 2013

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Article

Measurement of mid-arm muscle circumference and prognosis in stage IV non-small cell lung cancer patients

Rafaela Festugatto Tartari, Jane Maria Ulbrich‑Kulczynski, Antônio Fabiano Ferreira Filho
Pages: 1063-1067
Published online on: 11 January 2013

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Article

The hyaluronan synthesis inhibitor 4-methylumbelliferone exhibits antitumor effects against mesenchymal‑like canine mammary tumor cells

Teruyoshi Saito, Tamura Dai, Ryuji Asano
Pages: 1068-1074
Published online on: 10 January 2013

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Article

Activated amelogenin Y-linked (AMELY) regulation and angiogenesis in human hepatocellular carcinoma by biocomputation

Lianxiu Qi, Lin Wang, Juxiang Huang, Minghu Jiang, Haizhen Diao, Huilei Zhou, Xiaohe Li, Zhenfu Jiang
Pages: 1075-1079
Published online on: 10 January 2013

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July-2026 Volume 32 Issue 1

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Journal Metrics

Impact Factor: 2.2

CiteScore: 3.7

CiteScore Rank: Q3: #233/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Clinicopathological characterization of cervical squamous cell carcinoma with PIK3CA hotspot mutation: A single‑institution study

Jason Murray, Harsimar Kaur, Colton Smith, Annie A. Wu, Lee Shu-Fune Wu, Ya-Chea Tsai, Chien-Fu Hung, T.-C. Wu, Deyin Xing
Article Number: 321
Published online on: 02 June 2026

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Correction Open Access

[Corrigendum] Effect of overexpression of HOX genes on its invasive tendency in cerebral glioma

Yun-Bao Guo, Yi-Meng Shao, Jing Chen, Song-Bai Xu, Xing-Dong Zhang, Mao-Ren Wang, Hai-Yan Liu
Article Number: 320
Published online on: 02 June 2026

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Case Report Open Access

Immune checkpoint inhibitors for invasive mucinous adenocarcinoma: A case series

Tatsuya Kato, Takahiro Mitsumura, Eiyu Tsuboi, Hiroshi Nakahama, Yui Takahashi, Yuichiro Nei, Shigeo Hanada, Atsushi Miyamoto, Hironori Uruga, Takeshi Fujii, Meiyo Tamaoka
Article Number: 319
Published online on: 29 May 2026

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Development and validation of a prognostic nomogram incorporating preoperative NLR, CEA and CA19‑9 for overall survival in colorectal cancer

Bo Shi, Haoran Guo, Junjie Chen, Zhijian Peng, Suo Wang, Guoliang Chen, Qingliang Tai, Xinyu Shi, Songbing He
Article Number: 318
Published online on: 29 May 2026

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Article

Survival prediction in stage II/III rectal cancer: Role of immune‑inflammatory biomarkers post neoadjuvant chemoradiotherapy

Bingjie Li, Taotao Huang, Shijing Xu, Yuhuan Ye, Yong Liu, Xiaoyu Wang, Yongsheng Wang
Article Number: 317
Published online on: 29 May 2026

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LATS2 expression differences in lung adenocarcinoma and lung squamous cell carcinoma analyzed using bioinformatics and experimental approaches

Zhen Zhang, Shaoyan Zhang, Yalai Xu, Changyu Zhang, Xudong Zhang
Article Number: 316
Published online on: 28 May 2026

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Expression of Concern Open Access

[Expression of Concern] lncRNA HOTTIP facilitates osteosarcoma cell migration, invasion and epithelial‑mesenchymal transition by forming a positive feedback loop with c‑Myc

Yang Tang, Fang Ji
Article Number: 315
Published online on: 26 May 2026

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Lectin‑captured plasma microRNAs predict response and survival in patients with non‑small cell lung cancer treated with nivolumab

Eiji Narusawa, Yukiko Nakano, Seshiru Nakazawa, Kanji Hori, Yoichi Ohtaki, Natsuko Kawatani, Tomohiro Yazawa, Ryohei Yoshikawa, Kazuki Numajiri, Ryo Kuriyama, Hiroshi Kurokawa, Yoshihiro Taguchi, Seyed Mostafa Mostafavi Zadeh, Haruka Okami, Takuya Shiraishi, Nobuhiro Nakazawa, Takamichi Igarashi, Kyoichi Kaira, Hiroshi Saeki, Ken Shirabe, Takehiko Yokobori
Article Number: 314
Published online on: 25 May 2026

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Review

Cancer stem cells and their molecular signaling mechanisms in tongue squamous cell carcinoma (Review)

Xuqiang Guo, Xuan Zhou, Wen Ran, Qiao Zhu, Wei Chen, Chengcheng Ma
Article Number: 313
Published online on: 25 May 2026

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Pathological response and tumor regression grading following neoadjuvant chemo‑immunotherapy and chemotherapy in resectable non‑small cell lung cancer

Özge Kaya Korkmaz, Yaren Sari Çataldaş, Nazlican Saltik Barel, Mehmet Büyükevli
Article Number: 312
Published online on: 22 May 2026

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D‑salicin induces oxidative stress‑mediated ERK1/2 suppression and apoptosis in endometrial cancer cells

Neziha Senem Ari, Ayşe Çakir Gündoğdu
Article Number: 311
Published online on: 22 May 2026

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Decoding the role of polyamine metabolism in lung adenocarcinoma prognosis: A triangulated approach combining transcriptome, single‑cell and Mendelian randomization analyses

Hua Yang, Lemeng Zhang, Jianhua Chen, Junjie Zhang
Article Number: 310
Published online on: 21 May 2026

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Correction Open Access

[Corrigendum] Antitumor effects of dioscin in A431 cells via adjusting ATM/p53‑mediated cell apoptosis, DNA damage and migration

Peng Wang, Chun Wang, Chunying Liu
Article Number: 309
Published online on: 21 May 2026

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Review Open Access

Targeting non‑small cell lung cancer: Molecular mechanisms and clinical studies (Review)

Ying Luo, Guofang Yin, Xiaoqin Luo, Yue Liu, Kaiyu Jin, Zhiguo Wang
Article Number: 308
Published online on: 20 May 2026

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Histopathological changes in primary extramammary Paget disease with emphasis on syringomatous structures and syringocystadenocarcinoma papilliferum in situ‑like changes

Yutaro Fukuma, Mitsuaki Ishida, Yoshinobu Hirose
Article Number: 307
Published online on: 20 May 2026

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Case Report Open Access

Durable response to selpercatinib in HOOK3‑RET fusion positive, α‑fetoprotein producing metastatic pancreatic ductal adenocarcinoma with intestinal‑type differentiation

Harsahib Singh Sandhu, Aparna Natarajan, Smiley Joshi
Article Number: 306
Published online on: 20 May 2026

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Correction Open Access

[Corrigendum] PVT1 promotes resistance to 5‑FU in colon cancer via the miR‑486‑5p/CDK4 axis

Zhuhe Luo, Ruijun Chen, Shen Hu, Xibin Huang, Zhenyi Huang
Article Number: 305
Published online on: 20 May 2026

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Case Report Open Access

Pelvic schwannoma misdiagnosed as colorectal cancer metastasis and the corresponding diagnostic lessons: A report of two cases

Shilong Wang, Kaixiang Zhang, Xiangwu Lin, Feilai Xie, Jian Yang, Jie Li
Article Number: 304
Published online on: 19 May 2026

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Case Report

Multidetector computed tomography detection of perineural infiltration around the superior mesenteric artery in intrahepatic cholangiocarcinoma: A case report

Myeong Hun Oh, Byeong Gwan Noh, Hyung Il Seo, Young Mok Park, Suk Kim, Nam Kyung Lee, Seung Baek Hong
Article Number: 303
Published online on: 19 May 2026

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Review Open Access

Clinical implications of lactylation modification in digestive system tumors (Review)

Lin Pan, Fengye Liu, Wenjing Yu
Article Number: 302
Published online on: 19 May 2026

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Article Open Access

Rare BRCA1 c.3418_3419insTGACTACT:p.S1140Mfs*18 germline mutation in a family with breast and ovarian cancer

Chao Zhai, Long Jia, Chaoyang Wang, Liang Chen, Tuo Han, Dong Xiao
Article Number: 301
Published online on: 19 May 2026

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Expression of Concern Open Access

[Expression of Concern] miR‑148a inhibits cell proliferation and migration through targeting ErbB3 in colorectal cancer

Wei Zhao, Jianbao Zheng, Guangbing Wei, Kui Yang, Guanghui Wang, Xuejun Sun
Article Number: 300
Published online on: 19 May 2026

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Article Open Access

Prognostic significance of squamous differentiation in pT2N0 urothelial bladder cancer

Alper Coskun, Ahmet Bilgehan Sahin, Selva Kabul, Mehmet Emin Dagtekin, Seda Sali, Buket Erkan Ozmarasali, Adem Deligonul, Erdem Cubukcu, Meral Kurt, Gursel Savci, Turkkan Evrensel, Ismet Yavascaoglu
Article Number: 299
Published online on: 18 May 2026

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Article

Jaceosidin inhibits cell viability and induces apoptosis in non‑small cell lung cancer by inhibiting the Ras/Raf/MEK/ERK and Akt pathways

Xiaodie Cao, Chong Ma, Xin Wang, Cui Wang, Lanlin Shen, Jingru Wei, Rongmin Yang, Yan Li, Xu He, Li Chen
Article Number: 298
Published online on: 18 May 2026

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Review Open Access

Ubiquitination and N6‑methyladenosine in cancer: Convergent regulation of oncogenic signaling pathways (Review)

Hailong Li, Xuelin Lu
Article Number: 297
Published online on: 18 May 2026

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Correction Open Access

[Corrigendum] TERT promoter regulating melittin expression induces apoptosis and G0/G1 cell cycle arrest in esophageal carcinoma cells

Chao Zhou, Jie Ma, Yuanhua Lu, Wan Zhao, Bingxue Xu, Jian Lin, Yongjun Ma, Yafei Tian, Qi Zhang, Wei Wang, Weiqun Yan, Ping Jiao
Article Number: 296
Published online on: 15 May 2026

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Case Report Open Access

Primary endometrioid adenocarcinoma of the vagina after total hysterectomy for adenomyosis: A case report

Tingting Wang, Xin Li, Liping Chen, Jing Zhang, Lina Peng, Haitao Yang
Article Number: 295
Published online on: 14 May 2026

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Correction Open Access

[Corrigendum] Tanshinol upregulates the expression of aquaporin 5 in lung tissue of rats with sepsis

Jianfeng Xu, Lei Yang, Liang Dong
Article Number: 294
Published online on: 14 May 2026

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Article Open Access

Weekly cisplatin and nab‑paclitaxel neoadjuvant chemoradiotherapy increases pathological complete response in locally advanced esophageal squamous cell carcinoma: A real‑world study

Li Li, Xuquan Jing, Jiling Niu, Yan Yi, Yujie Wang, Ke Zhao, Jingyu Luo, Jinming Yu, Hui Zhu
Article Number: 293
Published online on: 13 May 2026

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Article Open Access

Gastrointestinal cancer with indeterminate 18F‑FDG PET/CT findings: Diagnostic efficacy analysis of 68Ga‑FAPI‑04 PET/MRI

Jingxuan Miao, Yifei Xu, Feng Qiao, Ni Chen, Muhammad Imran Khan, Ye Zhao, Hui Wang
Article Number: 292
Published online on: 13 May 2026

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Article Open Access

Breaking senescence restriction: MAFK‑AREG axis promotes NSCLC cells to resist doxorubicin

Ningning Fan, Guanying Liang, Jiayue Shao, Qi Wang, Lu Fu
Article Number: 291
Published online on: 13 May 2026

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Expression of Concern Open Access

[Expression of Concern] Rap2B promotes the proliferation and migration of human glioma cells via activation of the ERK pathway

Guohong Shi, Zhen Zhang
Article Number: 290
Published online on: 11 May 2026

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Article Open Access

A novel prognostic biomarker combining TP53 loss‑of‑function and amplification of different combinations of nine genes in lung squamous cell carcinoma treated with chemotherapy

Yuli Li, Ting Hou, Hongjie Liu, Haiwei Du, Li Qiu, Yajing Zhang, Guiping Zhang, Yuan Tang
Article Number: 289
Published online on: 11 May 2026

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Article Open Access

Meta‑analysis of efficacy comparisons between standard‑ and low‑dose Bacillus Calmette‑Guerin vaccines in managing non‑muscular invasive bladder cancer

Xiaoxi Liu, Yige Bao
Article Number: 288
Published online on: 08 May 2026

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Correction Open Access

[Corrigendum] EGFR and ERK activation resists flavonoid quercetin‑induced anticancer activities in human cervical cancer cells in vitro

Xin Chen, Pengli Xu, Huijun Zhang, Xiaosan Su, Lihua Guo, Xuhong Zhou, Junliang Wang, Peng Huang, Qingzhi Zhang, Ruifen Sun
Article Number: 287
Published online on: 08 May 2026

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Article Open Access

Cumulative evidence for associations between matrix metalloproteinase‑1, ‑3 and ‑8 variants and cancer risk

Suqin Xu, Xianping Liu, Chenglu Huang
Article Number: 286
Published online on: 07 May 2026

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Article

PD‑1 inhibitors combined with tyrosine kinase inhibitor‑associated hypothyroidism is a predictive factor for antitumor effectiveness in male patients with hepatocellular carcinoma

Bailu Cao, Min Ai, Ping Huang, Huan Zhong
Article Number: 285
Published online on: 07 May 2026

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Correction Open Access

[Corrigendum] Proliferation, migration and invasion of triple negative breast cancer cells are suppressed by berbamine via the PI3K/Akt/MDM2/p53 and PI3K/Akt/mTOR signaling pathways

Lili Liu, Jiadong Yan, Ying Cao, Yan Yan, Xiang Shen, Binbin Yu, Li Tao, Shusheng Wang
Article Number: 284
Published online on: 06 May 2026

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Article Open Access

Evaluation of ct‑DNA and mutational status in liquid biopsy of patients with metastatic colorectal cancer

George Zarkavelis, Melina Yerolatsite, Panagiotis Ntellas, Aikaterini Tsantikidi, Irene Papadopoulou, Nanteznta Torounidou, Katerina Dadouli, George Nasioulas, Eleftherios Kampletsas, George Pentheroudakis
Article Number: 283
Published online on: 06 May 2026

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Article Open Access

Immunotherapy retreatment with serplulimab vs. chemotherapy in extensive‑stage advanced small cell lung cancer

Xinhang Gu, Xue Wu, Jiaxiao Geng, Yan Wang, Chengxin Liu
Article Number: 282
Published online on: 06 May 2026

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Article Open Access

Next‑generation sequencing elucidates the distinct mutational landscape of SMARCA4‑deficient lung cancer

Feicheng Yang, Yuzhong Yang, Zhihong Chen, Yanchun Li, Yinghui Song
Article Number: 281
Published online on: 05 May 2026

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Correction Open Access

[Corrigendum] Eupafolin inhibits breast cancer cell proliferation and induces apoptosis by inhibiting the PI3K/Akt/mTOR pathway

Jiahui Wei, Xuefeng Zhang, Huihao Pan, Song He, Bao Yuan, Qing Liu, Jiabao Zhang, Yu Ding
Article Number: 280
Published online on: 05 May 2026

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Article

Mutational landscape in the precancerous stages of sporadic colorectal cancer

Anna Valickova, Marketa Urbanova, Josef Horak, Jiri Jungwirth, Jan Kral, Tomas Hucl, Veronika Makajevova, Sandra Summerova, Pavel Kohout, Radoslav Matej, Pavel Vodicka, Veronika Vymetalkova
Article Number: 279
Published online on: 04 May 2026

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Article Open Access

Comparing the efficacy of immune checkpoint inhibitors with and without microwave ablation in advanced hepatocellular carcinoma in real‑world clinical practice: A retrospective cohort study

Chun Wei, Sizhong Chen, Li Ding, Ting Zhou, Fan Huang, Yong Wang, Ou Jiang, Yu Liu
Article Number: 278
Published online on: 04 May 2026

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Expression of Concern Open Access

[Expression of Concern] FHOD1 is upregulated in gastric cancer and promotes the proliferation and invasion of gastric cancer cells

Chengfei Jiang, Binbin Yuan, Bo Hang, Jian-Hua Mao, Xiaoping Zou, Pin Wang
Article Number: 277
Published online on: 29 April 2026

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Review Open Access

Watch‑and‑wait in rectal cancer: A critical appraisal of promise, perils and unresolved contours of organ preservation (Review)

Xinqiang Zhu, Beibei Ge, Linchun Wen, Siwei Shan
Article Number: 276
Published online on: 28 April 2026

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Review Open Access

Multi‑omics profiling of pancreatic neuroendocrine tumors: Interplay of genomic instability and the tumor microenvironment (Review)

Yin Wan, Yingnan Zhang, Philip A. Philip, Herbert Chen, Bassel El‑Rayes, Asfar S. Azmi, Yang Shi
Article Number: 275
Published online on: 28 April 2026

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Article Open Access

SOX2‑positive upper tract urothelial carcinoma: Clinicopathological characteristics and therapeutic implications

Hitomi Yasukawa, Yoshinori Ikehata, Naotaka Nishiyama, Hiroshi Kitamura
Article Number: 274
Published online on: 28 April 2026

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Case Report Open Access

Diagnostic and therapeutic challenges of locally advanced colon cancer complicated with acute lymphoblastic leukemia: A case report

Yuping Zeng, Song Mu, Guosheng Li, Zhengzi Liang, Qinghua Ji, Yunhuan Zhen, Wenling Wang, Weiwei Chen
Article Number: 273
Published online on: 28 April 2026

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Article Open Access

LINC00184 promotes esophageal squamous cell carcinoma progression via DNMT1‑mediated methylation of the NDRG2 promoter and PI3K/AKT pathway activation

Junjun Guo, Shenbo Fu, Jia Liu, Lina Li, Jin Zhao, Fenggang Wang, Wenan Wu, Xu Chen, Enxiao Li
Article Number: 272
Published online on: 28 April 2026

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Case Report Open Access

A clear cell sarcoma tumor of the finger with an unusual presentation misdiagnosed as a glomus tumor in an adolescent patient: A case report

Abdulrahman Alaseem, Hatim Khoja, Khalid Murrad, Sarah Alkhalife, Nouf Altwaijri, Abdullah Almawi, Abdulaziz Bin Dakhil, Abdulaziz Alhammad, Banan Alqady, Eman Najjar
Article Number: 271
Published online on: 28 April 2026

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Case Report Open Access

Primary thyroid lymphoma with Hashimoto's thyroiditis: A case report and literature review

Fangshu Liu, Xueya Xin, Kai Tan, Xinv Chen, Chanjuan Shen, Qiuhong Yang
Article Number: 270
Published online on: 28 April 2026

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Expression of Concern Open Access

[Expression of Concern] In vitro and in vivo inhibition of tumor cell viability by combined dihydroartemisinin and doxorubicin treatment, and the underlying mechanism

Xiang Tai, Xiao-Bei Cai, Zhang Zhang, Rui Wei
Article Number: 269
Published online on: 28 April 2026

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Journal Cover
August-2026 Volume 32 Issue 2

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Journal Metrics

Impact Factor: 2.2

CiteScore: 3.7

CiteScore Rank: Q3: #233/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Review Open Access

Advantages and research progress of three‑dimensional culture systems for lung cancer drug screening (Review)

Yihe Tian, Hai Liu, Minhong Zhang, Aiping Cui, Hao Chen, Lei Shi, Junyao Zhu, Mingchun Li, Biao Wang, Hao Huang, Jianqiong Yang
Article Number: 347
Published online on: 12 June 2026

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Correction Open Access

[Corrigendum] MicroRNA‑182 promotes epithelial‑mesenchymal transition by targeting FOXN3 in gallbladder cancer

Jianhong Zhang, Zeming Hu, Chao Wen, Qicheng Liao, Baoqing He, Jing Peng, Xin Tang, Zhixi Chen, Yuankang Xie
Article Number: 346
Published online on: 12 June 2026

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Article Open Access

Lactate‑to‑albumin ratio as an independent predictor of short‑ and long‑term mortality in ICU patients with malignant tumors: A retrospective cohort study

Jingchao Bai, Yihan Xu, Ke Wang, Xin Fu
Article Number: 345
Published online on: 12 June 2026

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Case Report

Long‑term survival with tocilizumab treatment for tislelizumab‑related pneumonitis in a patient with non‑small cell lung cancer: A case report

Lan Yu, Qing-Ming Guo, Li Liu, Yu Wang, Fei Chen, Xiao-Tao Zhang
Article Number: 344
Published online on: 11 June 2026

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Correction Open Access

[Corrigendum] Engineered AXL‑ECD‑Fc variants that abolish the AXL/Gas6 interaction suppress tumor cell migration

Yanting Duan, Bo Hu, Chunxia Qiao, Xinying Li, Jing Wang, Hao Liu, Tingting Zhou, Beifen Shen, Ming Lv, Jiannan Feng
Article Number: 343
Published online on: 11 June 2026

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Review

Spatiotemporal heterogeneity in non‑small cell lung cancer: A paradigm shift from characterization to dynamic management (Review)

Li Cao, Wei Zhang
Article Number: 342
Published online on: 11 June 2026

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Article Open Access

Comprehensive bioinformatics analysis of NCAPH expression and its clinical importance in endometrial cancer

Yuxiu Huang, Kang Kang, Qian Zhuo, Qianqian Ma, Yujie Xue, Yaning Zhu, Mingde Huang
Article Number: 341
Published online on: 11 June 2026

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Case Report Open Access

Diffuse peritoneal mesothelioma presenting with the appearance of mesenteric panniculitis: A case report

Yunfeng Chen, Qiong Fu, Jialing Xu, Rong Wang, Yongxiang Mo, Yuan Liu
Article Number: 340
Published online on: 11 June 2026

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Article Open Access

Construction and validation of a predictive model of pathological complete response combined with MRI and tumor indicators for HER2‑positive breast cancer after neoadjuvant targeted therapy

Keying Zhu, Zeying Li, Jiaqian Liao, Changan Wang, Rong Guo, Yiyin Tang, Shaoqiang Zhou, Yingying Ding, Dedian Chen, Jiankui Wang, Jianyun Nie, Sheng Huang
Article Number: 339
Published online on: 11 June 2026

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Article Open Access

Tanshinone IIA suppresses cancer metastasis by modulating tumor cell‑platelet‑endothelial cell interactions

Judan Xu, Lin Luo, Feiyang Li, Siying Wang, Chengbin Fu, Guihua Wang, Yanhong Wang, Yusheng Lu
Article Number: 338
Published online on: 11 June 2026

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Article Open Access

RTA‑408 induces JNK‑dependent apoptosis and autophagy in breast cancer cells

Yu-Jen Chen, Hung-Pei Tsai, Mei-Yin Chen, I-Hsiang Chen, Wei-Chieh Chen, Tzu-Ting Tseng, Chen-Yu Wang, Jia-Hau Lee
Article Number: 337
Published online on: 11 June 2026

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Case Report Open Access

Vanishing liver metastases in pancreatic cancer: A case report

Evangelia Florou, Paul Ross, Parthi Srinivasan, Andreas Prachalias
Article Number: 336
Published online on: 11 June 2026

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Case Report Open Access

Long survival of PD‑L1‑positive mediastinal sarcomatoid carcinoma after immunotherapy and anti‑angiogenic target therapy: A case report

Shuling Wu, Danping Wang, Qiong Fu, Yingying Ding
Article Number: 335
Published online on: 11 June 2026

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Case Report

Primary malignant melanoma of the common bile duct: An unexpected finding at pancreaticoduodenectomy: A case report

Evangelia Florou, Hamad Almakinzy, Yoh Zen, Parthi Srinivasan, Andreas Prachalias
Article Number: 334
Published online on: 11 June 2026

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Correction Open Access

[Corrigendum] Imatinib mesylate and nilotinib decrease synthesis of bone matrix in vitro

Lysann Michaela Kroschwald, Osephine Tabea Tauer, Sonja Ingrid Kroschwald, Meinolf Suttorp, Anne Wiedenfeld, Stefan Beissert, Andrea Bauer, Martina Rauner
Article Number: 333
Published online on: 10 June 2026

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Retraction Open Access

[Retracted] Combined application of Embelin and tumor necrosis factor‑related apoptosis‑inducing ligand inhibits proliferation and invasion in osteosarcoma cells via caspase‑induced apoptosis

Hao Qian, Yao Chen, Tao Huang, Tiemin Liu, Xiucheng Li, Guangjian Jiang, Wei Zhang, Shuo Cheng, Pengcheng Li
Article Number: 332
Published online on: 08 June 2026

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Article Open Access

Cepharanthine suppresses lung adenocarcinoma through targeting glutathione peroxidase 4

Ruoxue Cao, Sun Kang, Kun Wang, Yan Wang, Minghui Li, Qian Liu, Ying Zhang, Mei Fu
Article Number: 331
Published online on: 08 June 2026

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Case Report Open Access

Adrenal lymphoma with hypertension: A report of three cases

Kunlei Tan, Zhijun Han, Yali Zhou, Miduo Tan, Lei Chen, Yinchun Deng
Article Number: 330
Published online on: 05 June 2026

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Case Report

Undifferentiated pelvic sarcoma 5 years post‑radiochemotherapy for rectal adenocarcinoma: A case report

Yang Yang, Yubin Long
Article Number: 329
Published online on: 05 June 2026

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Case Report Open Access

Locally advanced breast cancer in an elderly male with end‑stage renal disease: A case report

Mengfan Chen, Ming Feng, Xiaoyu Li, Huanhuan Wang, Ke Hong, Chang Yao
Article Number: 328
Published online on: 05 June 2026

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Case Report

Warm autoimmune hemolytic anemia following definitive chemoradiotherapy for cervical cancer: A case report

Yuanyuan Kong, Liangxue Zhu, Yuelan Xiao
Article Number: 327
Published online on: 05 June 2026

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Article Open Access

A cross‑platform transcriptomic risk score integrating LymphoMAP microenvironment archetypes and immune evasion‑associated programs in diffuse large B‑cell lymphoma

Xiaochang Chen, Jin Zhang, Shenhe Jin, Luqiao Wang, Ye Zhang
Article Number: 326
Published online on: 03 June 2026

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Expression of Concern Open Access

[Expression of Concern] Effect of fibroblast co‑culture on the proliferation, viability and drug response of colon cancer cells

Byumseok Koh, Hyojin Jeon, Dahee Kim, Dukjin Kang, Kwang Rok Kim
Article Number: 325
Published online on: 03 June 2026

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Review

Biological and pathogenic roles of major genes harbored in intrachromosomal amplification of chromosome 21 in childhood acute lymphoblastic leukemia (Review)

Conrado Emilio Uría‑Gómez, Hugo Mendieta‑Zerón, Jazmín Arteaga‑Vázquez, Antonio Sandoval‑Cabrera
Article Number: 323
Published online on: 03 June 2026

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Article Open Access

IL‑37 drives temozolomide resistance in glioblastoma via MAPK pathway activation

Yu Wang, Ying Liu, Jingyi Wang, Wei Rong, Xue Song
Article Number: 322
Published online on: 03 June 2026

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