Effect of UVB irradiation on microRNA expression in mouse epidermis

  • Authors:
    • Bing-Rong Zhou
    • Yang Xu
    • Dan Luo
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  • Published online on: January 3, 2012     https://doi.org/10.3892/ol.2012.551
  • Pages: 560-564
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Abstract

The aim of this study was to assess the effects of UVB irradiation on miRNA expression in the mouse epidermis. We determined miRNA expression profiles in the epidermis of UVB irradiated mice and untreated mice, and conducted TargetScan and Gene Ontology analyses to predict miRNA targets. Three miRNAs were downregulated and three were upregulated in the epidermis of UVB irradiated mice compared with untreated mice, and were predicted to be associated with photocarcinogenesis, hypomethylation and apoptosis. miRNAs are potentially involved in the pathogenesis of photodamage, and may aid in the treatment and prevention of UVB-induced dermatoses.
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March 2012
Volume 3 Issue 3

Print ISSN: 1792-1074
Online ISSN:1792-1082

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Spandidos Publications style
Zhou B, Xu Y and Luo D: Effect of UVB irradiation on microRNA expression in mouse epidermis. Oncol Lett 3: 560-564, 2012
APA
Zhou, B., Xu, Y., & Luo, D. (2012). Effect of UVB irradiation on microRNA expression in mouse epidermis. Oncology Letters, 3, 560-564. https://doi.org/10.3892/ol.2012.551
MLA
Zhou, B., Xu, Y., Luo, D."Effect of UVB irradiation on microRNA expression in mouse epidermis". Oncology Letters 3.3 (2012): 560-564.
Chicago
Zhou, B., Xu, Y., Luo, D."Effect of UVB irradiation on microRNA expression in mouse epidermis". Oncology Letters 3, no. 3 (2012): 560-564. https://doi.org/10.3892/ol.2012.551