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May 2012 Volume 3 Issue 5

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Article

Meningeal tumor: A rare extrahepatic association in patients with polycystic liver disease enrolled for liver transplantation

  • Authors:
    • Alexandre Bakonyi Neto
    • Marco Antonio Zanini
    • Amanda Pinter Cavalheiro da Silva
    • Camila Winckler
    • Rodrigo Mattos dos Santos
    • Marcelo Lopes Furtado
  • View Affiliations / Copyright

    Affiliations: Department of Surgery, Division of Gastrointestinal Transplant, Botucatu Faculty of Medicine, UNESP, Botucatu, SP, Brazil, Department of Neurosurgery, Botucatu Faculty of Medicine, UNESP, Botucatu, SP, Brazil, Department of Urology, Botucatu Faculty of Medicine, UNESP, Botucatu, SP, Brazil
  • Pages: 1007-1010
    |
    Published online on: February 10, 2012
       https://doi.org/10.3892/ol.2012.605
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Abstract

In the present study, we described a rare association of polycystic liver disease (PCLD) with intracranial meningiomas in patients included on a liver transplant list, focusing on the diagnosis, treatment and possible association with any genetic alterations. Two female patients, aged 39 and 49 years were included on a liver transplant list due to extensive PCLD, with symptoms related to an abdominal compartmental syndrome. Screening for extrahepatic manifestation revealed a right frontal meningioma in the first patient, and a parietal posterior calcified meningioma in the second patient, measuring 1 and 7x3x2 cm in diameter, respectively. Following tumor removal, the histological pattern was compatible with fibrous and transitional meningioma, respectively. Cytogenetic studies conducted following surgery did not reveal any changes in metaphase chromosomes. The postoperative follow-up for the two patients was uneventful, without complications, with the patients remaining on a liver transplant waiting list. We conclude that screening for extrahepatic manifestations of PCLD is mandatory, as certain lesions require treatment prior to liver transplantation. The lack of a genetic or familial association between these two cases show they are likely to have occurred by chance, rather than representing a previously unrecognized association between polycystic liver disease and cranial meningioma.
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Copy and paste a formatted citation
Spandidos Publications style
Bakonyi Neto A, Zanini MA, Cavalheiro da Silva AP, Winckler C, Mattos dos Santos R and Lopes Furtado M: Meningeal tumor: A rare extrahepatic association in patients with polycystic liver disease enrolled for liver transplantation. Oncol Lett 3: 1007-1010, 2012.
APA
Bakonyi Neto, A., Zanini, M.A., Cavalheiro da Silva, A.P., Winckler, C., Mattos dos Santos, R., & Lopes Furtado, M. (2012). Meningeal tumor: A rare extrahepatic association in patients with polycystic liver disease enrolled for liver transplantation. Oncology Letters, 3, 1007-1010. https://doi.org/10.3892/ol.2012.605
MLA
Bakonyi Neto, A., Zanini, M. A., Cavalheiro da Silva, A. P., Winckler, C., Mattos dos Santos, R., Lopes Furtado, M."Meningeal tumor: A rare extrahepatic association in patients with polycystic liver disease enrolled for liver transplantation". Oncology Letters 3.5 (2012): 1007-1010.
Chicago
Bakonyi Neto, A., Zanini, M. A., Cavalheiro da Silva, A. P., Winckler, C., Mattos dos Santos, R., Lopes Furtado, M."Meningeal tumor: A rare extrahepatic association in patients with polycystic liver disease enrolled for liver transplantation". Oncology Letters 3, no. 5 (2012): 1007-1010. https://doi.org/10.3892/ol.2012.605
Copy and paste a formatted citation
x
Spandidos Publications style
Bakonyi Neto A, Zanini MA, Cavalheiro da Silva AP, Winckler C, Mattos dos Santos R and Lopes Furtado M: Meningeal tumor: A rare extrahepatic association in patients with polycystic liver disease enrolled for liver transplantation. Oncol Lett 3: 1007-1010, 2012.
APA
Bakonyi Neto, A., Zanini, M.A., Cavalheiro da Silva, A.P., Winckler, C., Mattos dos Santos, R., & Lopes Furtado, M. (2012). Meningeal tumor: A rare extrahepatic association in patients with polycystic liver disease enrolled for liver transplantation. Oncology Letters, 3, 1007-1010. https://doi.org/10.3892/ol.2012.605
MLA
Bakonyi Neto, A., Zanini, M. A., Cavalheiro da Silva, A. P., Winckler, C., Mattos dos Santos, R., Lopes Furtado, M."Meningeal tumor: A rare extrahepatic association in patients with polycystic liver disease enrolled for liver transplantation". Oncology Letters 3.5 (2012): 1007-1010.
Chicago
Bakonyi Neto, A., Zanini, M. A., Cavalheiro da Silva, A. P., Winckler, C., Mattos dos Santos, R., Lopes Furtado, M."Meningeal tumor: A rare extrahepatic association in patients with polycystic liver disease enrolled for liver transplantation". Oncology Letters 3, no. 5 (2012): 1007-1010. https://doi.org/10.3892/ol.2012.605
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