Two papillary renal cell carcinomas of different origin following renal transplantation (Case report)

Gerth,Hans-Ulrich; Pohlen,Michele; Thoennissen,Nils-Heinrich; Suwelack,Barbara; Pavenstädt,Hermann-Josef; Störkel,Stefan; Abbas,Mahmoud; Spieker,Tilmann; Thölking,Gerold

doi:10.3892/ol.2012.704

July 2012 Volume 4 Issue 1

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July 2012 Volume 4 Issue 1

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Case Report

Two papillary renal cell carcinomas of different origin following renal transplantation (Case report)

Authors:
- Hans-Ulrich Gerth
- Michele Pohlen
- Nils-Heinrich Thoennissen
- Barbara Suwelack
- Hermann-Josef Pavenstädt
- Stefan Störkel
- Mahmoud Abbas
- Tilmann Spieker
- Gerold Thölking
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Affiliations: Department of Medicine D, Division of General Internal Medicine, Nephrology and Rheumatology, University Hospital of Münster, D-48149 Münster, Germany , Department of Medicine A, - Hematology/Oncology, University Hospital of Münster, D-48149 Münster, Germany, Department of Pathology, Helios Hospital, D-42283 Wuppertal, Germany, Department of Pathology, University Hospital Münster, Germany
Pages: 80-82
|
Published online on: May 4, 2012

https://doi.org/10.3892/ol.2012.704
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Abstract

Papillary renal cell carcinoma (PRCC) is a rare malignant tumor entity compared to common clear cell renal carcinoma. In the present study, we report a patient who was diagnosed with PRCC twice and successfully treated each time following renal transplantation. The first PRCC was located in the left native kidney two years following transplantation, and the second PRCC was diagnosed in the allograft 13 years following transplantation. The two tumors were completely removed by surgery in stage I of the disease with sufficient conservation of the allograft function. Notably, the tumors had a different origin as indicated by the microsatellite analysis, which reflects the exceptional course of the case. Risk factors for PRCC were identified in our patient. We concluded that high-risk candidates for malignancies in renal transplant recipients should receive shorter ultrasonic screening intervals, which may facilitate early tumor detection and improve outcome rates.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Two papillary renal cell carcinomas of different origin following renal transplantation (Case report)

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