A case of carcinomatous meningitis despite prophylactic cranial irradiation in small cell lung cancer during treatment with amrubicin

Oguri,Tetsuya; Uemura,Takehiro; Kunii,Eiji; Ozasa,Hiroaki; Ohkubo,Hirotsugu; Miyazaki,Mikinori; Maeno,Ken; Sato,Shigeki

doi:10.3892/ol.2012.725

August 2012 Volume 4 Issue 2

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August 2012 Volume 4 Issue 2

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Article

A case of carcinomatous meningitis despite prophylactic cranial irradiation in small cell lung cancer during treatment with amrubicin

Authors:
- Tetsuya Oguri
- Takehiro Uemura
- Eiji Kunii
- Hiroaki Ozasa
- Hirotsugu Ohkubo
- Mikinori Miyazaki
- Ken Maeno
- Shigeki Sato
View Affiliations / Copyright

Affiliations: Department of Medical Oncology and Immunology, Nagoya City University Graduate School of Medical Sciences, Nagoya 467-8601, Japan
Pages: 305-306
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Published online on: May 22, 2012

https://doi.org/10.3892/ol.2012.725
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Abstract

A 47-year-old man was diagnosed with limited-disease small cell lung cancer. Treatment was initiated with concurrent chemotherapy and radiotherapy. A partial response was achieved, and prophylactic cranial irradiation (PCI) was administered. Local recurrence was identified on follow-up and treated with amrubicin (AMR). After two courses of AMR, a state of stable disease was achieved and AMR treatment was continued. After the third course of AMR, the patient was urgently hospitalized suffering from a headache and disturbance of consciousness, and a diagnosis of carcinomatous meningitis was made. This case report concerns a case of carcinomatous meningitis despite PCI during treatment with AMR.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

A case of carcinomatous meningitis despite prophylactic cranial irradiation in small cell lung cancer during treatment with amrubicin

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Abstract

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