|
1
|
Jemal A, Siegel R, Xu J and Ward E: Cancer
statistics, 2010. CA Cancer J Clin. 60:277–300. 2010. View Article : Google Scholar
|
|
2
|
Greenlee RT, Hill-Harmon MB, Murray T and
Thun M: Cancer statistics, 2001. CA Cancer J Clin. 51:15–36. 2001.
View Article : Google Scholar
|
|
3
|
Sobin L and Wittekind Ch: TNM
Classification of Malignant Tumors. 6th edition. Wiley-Liss; New
York: pp. 99–103. 2002
|
|
4
|
Luethy JD, Fargnoli J, Park JS, Fornace AJ
Jr and Holbrook NJ: Isolation and characterization of the hamster
gadd153 gene. Activation of promoter activity by agents that damage
DNA. J Biol Chem. 265:16521–16526. 1990.PubMed/NCBI
|
|
5
|
Ron D and Habener JF: CHOP, a novel
developmentally regulated nuclear protein that dimerizes with
transcription factors C/EBP and LAP and functions as a
dominant-negative inhibitor of gene transcription. Genes Dev.
6:439–453. 1992. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Ramji DP and Foka P:
CCAAT/enhancer-binding proteins: structure, function and
regulation. Biochem J. 365:561–575. 2002.PubMed/NCBI
|
|
7
|
Jousse C, Bruhat A, Carraro V, et al:
Inhibition of CHOP translation by a peptide encoded by an open
reading frame localized in the chop 5’UTR. Nucleic Acids Res.
29:4341–4351. 2001.PubMed/NCBI
|
|
8
|
Jackman J, Alamo I Jr and Fornace AJ Jr:
Genotoxic stress confers preferential and coordinate messenger RNA
stability on the five gadd genes. Cancer Res. 54:5656–5662.
1994.PubMed/NCBI
|
|
9
|
Wang XZ, Lawson B, Brewer JW, et al:
Signals from the stressed endoplasmic reticulum induce
C/EBP-homologous protein (CHOP/GADD153). Mol Cell Biol.
16:4273–4280. 1996.PubMed/NCBI
|
|
10
|
Bruhat A, Jousse C, Wang XZ, Ron D,
Ferrara M and Fafournoux P: Amino acid limitation induces
expression of CHOP, a CCAAT/enhancer binding protein-related gene,
at both transcriptional and post-transcriptional levels. J Biol
Chem. 272:17588–17593. 1997. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Sato N, Urano F, Yoon Leem J, et al:
Upregulation of BiP and CHOP by the unfolded-protein response is
independent of presenilin expression. Nat Cell Biol. 2:863–870.
2000. View
Article : Google Scholar : PubMed/NCBI
|
|
12
|
Uramoto H, Sugio K, Oyama T, et al:
Expression of endoplasmic reticulum molecular chaperone Grp78 in
human lung cancer and its clinical significance. Lung Cancer.
49:55–62. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Hsu WM, Hsieh FJ, Jeng YM, et al: GRP78
expression correlates with histologic differentiation and favorable
prognosis in neuroblastic tumors. Int J Cancer. 113:920–927. 2005.
View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Matsumoto M, Minami M, Takeda K, Sakao Y
and Akira S: Ectopic expression of CHOP (GADD153) induces apoptosis
in M1 myeloblastic leukemia cells. FEBS Lett. 395:143–147. 1996.
View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Barone MV, Crozat A, Tabaee A, Philipson L
and Ron D: CHOP (GADD153) and its oncogenic variant, TLS-CHOP, have
opposing effects on the induction of G1/S arrest. Genes Dev.
8:453–464. 1994. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Maytin EV, Ubeda M, Lin JC and Habener JF:
Stress-inducible transcription factor CHOP/gadd153 induces
apoptosis in mammalian cells via p38 kinase-dependent and
-independent mechanisms. Exp Cell Res. 267:193–204. 2001.
View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Oyadomari S and Mori M: Roles of
CHOP/GADD153 in endoplasmic reticulum stress. Cell Death Differ.
11:381–389. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Martini N, Bains MS, Burt ME, et al:
Incidence of local recurrence and second primary tumors in resected
stage I lung cancer. J Thorac Cardiovasc Surg. 109:120–129. 1995.
View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Downward J: Targeting RAS signalling
pathways in cancer therapy. Nat Rev Cancer. 3:11–22. 2003.
View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Cox AD and Der CJ: The dark side of Ras:
regulation of apoptosis. Oncogene. 22:8999–9006. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Rosen K, Rak J, Jin J, Kerbel RS, Newman
MJ and Filmus J: Downregulation of the pro-apoptotic protein Bak is
required for the ras-induced transformation of intestinal
epithelial cells. Curr Biol. 8:1331–1334. 1998. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Barradas M, Monjas A, Diaz-Meco MT,
Serrano M and Moscat J: The downregulation of the pro-apoptotic
protein Par-4 is critical for Ras-induced survival and tumor
progression. EMBO J. 18:6362–6369. 1999. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Nalca A, Qiu SG, El-Guendy N, Krishnan S
and Rangnekar VM: Oncogenic Ras sensitizes cells to apoptosis by
Par-4. J Biol Chem. 274:29976–29983. 1999. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Qiu SG, Krishnan S, el-Guendy N and
Rangnekar VM: Negative regulation of Par-4 by oncogenic Ras is
essential for cellular transformation. Oncogene. 18:7115–7123.
1999. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Rong R, Montalbano J, Jin W, et al:
Oncogenic Ras-mediated downregulation of Gadd153/CHOP is required
for Ras-induced cellular transformation. Oncogene. 24:4867–4872.
2005. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Wang XZ and Ron D: Stress-induced
phosphorylation and activation of the transcription factor CHOP
(GADD153) by p38 MAP Kinase. Science. 272:1347–1349. 1996.
View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Scott DW, Mutamba S, Hopkins RG and Loo G:
Increased GADD gene expression in human colon epithelial cells
exposed to deoxycholate. J Cell Physiol. 202:295–303. 2005.
View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Puthalakath H, O’Reilly LA, Gunn P, et al:
ER stress triggers apoptosis by activating BH3-only protein Bim.
Cell. 129:1337–1349. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
McCullough KD, Martindale JL, Klotz LO, Aw
TY and Holbrook NJ: Gadd153 sensitizes cells to endoplasmic
reticulum stress by down-regulating Bcl2 and perturbing the
cellular redox state. Mol Cell Biol. 21:1249–1259. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Friedman AD: GADD153/CHOP, a DNA
damage-inducible protein, reduced CAAT/enhancer binding protein
activities and increased apoptosis in 32D c13 myeloid cells. Cancer
Res. 56:3250–3256. 1996.PubMed/NCBI
|
|
31
|
Kim DG, You KR, Liu MJ, Choi YK and Won
YS: GADD153-mediated anticancer effects of
N-(4-hydroxyphenyl)retinamide on human hepatoma cells. J Biol Chem.
277:38930–38938. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Xia Y, Wong NS, Fong WF and Tideman H:
Upregulation of GADD153 expression in the apoptotic signaling of
N-(4-hydroxyphenyl)retinamide (4HPR). Int J Cancer. 102:7–14. 2002.
View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Korabiowska M, Cordon-Cardo C, Betke H, et
al: GADD153 is an independent prognostic factor in melanoma:
immunohistochemical and molecular genetic analysis. Histol
Histopathol. 17:805–811. 2002.PubMed/NCBI
|
|
34
|
Rask K, Thorn M, Ponten F, et al:
Increased expression of the transcription factors CCAAT-enhancer
binding protein-beta (C/EBBeta) and C/EBzeta (CHOP) correlate with
invasiveness of human colorectal cancer. Int J Cancer. 86:337–343.
2000. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Kim KM, Yu TK, Chu HH, et al: Expression
of ER stress and autophagy-related molecules in human non-small
cell lung cancer and premalignant lesions. Int J Cancer. Sept
27–2011.(Epub ahead of print).
|
