Two malignant solitary fibrous tumors in one kidney: Case report and review of the literature
- Authors:
- Guangning Zhao
- Gang Li
- Ruifa Han
View Affiliations
Affiliations: Department of Urology, Second Hospital of Tianjin Medical University, Tianjin Institute of Urology, Tianjin 300211, P.R. China
- Published online on: August 9, 2012 https://doi.org/10.3892/ol.2012.858
-
Pages:
993-995
Metrics: Total
Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
This article is mentioned in:
Abstract
Malignant solitary fibrous tumors of the kidney are very rare. Two tumors in one kidney is particularly rare and has not been previously reported. Due to the non-specific clinical symptoms, it is difficult but also very significant to give a definite diagnosis. Here, we report a case of two renal masses in one kidney. A 56-year-old man was admitted to our hospital complaining of shortness of breath, weakness, hyperhidrosis and intermittent hypoglycemia of 1-year duration without gross hematuria or lumbago. Imaging studies revealed two masses manifesting as inhomogeneous, with soft-tissue density and having no clear boundaries with the kidney. The patient was initially diagnosed with space-occupying lesions of the left kidney (with suspicions of renal cell carcinoma) and left radical nephrectomy was performed. Histologically, the tumors consisted of ovoid or spindle cells, and a hemangiopericytoma-like pattern and cellular atypia was observed in certain areas. Mitotic figures were more than 4 per 10 high-power fields. Immunohistochemically the tumor cells were positive for CD34, CD99 and vimentin. Accordingly, a diagnosis of malignant solitary fibrous tumor of the left kidney (low‑grade malignance) was established. Postoperative follow‑up of 10 months did not find tumor recurrence or metastasis and hypoglycemia was resolved with the removal of the tumors.
View References
|
1.
|
L RobinsonSolitary fibrous tumor of
pleuraCancer Control13264269200617075563
|
|
2.
|
A GelbM SimmonsN WeidnerSolitary fibrous
tumor involving the renal capsuleAm J Surg
Pathol2012881295199610.1097/00000478-199610000-000168827037
|
|
3.
|
M MarziP PiraM D’AlpaosA PaiuscoS
CanessaMS MinerviniP Di ZittiThe solitary fibrous malignant tumor
of the kidney: clinical and pathological considerations on a case
revisiting the literatureMinerva Urol
Nefrol63109113201121336250
|
|
4.
|
H TalvitieK AströmO LarssonSolitary
fibrous tumor of the prostate: A report of two casesPathol
Int61536538201110.1111/j.1440-1827.2011.02696.x21884303
|
|
5.
|
N FerrariL NieldFinal diagnosis: solitary
fibrous tumor of the kidneyClin Pediatr
(Phila)45871873200617080561
|
|
6.
|
SW FineDM McCarthyTY ChanMalignant
solitary fibrous tumor of the kidney: report of a case and
comprehensive review of the literatureArch Pathol Lab
Med130857861200616740040
|
|
7.
|
B HerrmannB SallerW KiessK MorgenrothK
DrochnerT SchröderPrimary malignant fibrous histiocytoma of the
lung: IGF-II producing tumor induces fasting hypoglycaemiaExp Clin
Endocr Diab108515518200010.1055/s-2000-1100711149628
|
|
8.
|
G MagroV CavallaroA TorrisiM LopesM
Dell’AlbaniS LanzafameIntrarenal solitary fibrous tumor of the
kidney report of a case with emphasis on the differential diagnosis
in the wide spectrum of monomorphous spindle cell tumors of the
kidneyPathol Res
Pract1983743200210.1016/S0344-0338(04)70182-X11866209
|
|
9.
|
T YazakiS SatohT IizumiT UmedaY
YamaguchiSolitary fibrous tumor of renal pelvisInt J
Urol8504508200110.1046/j.1442-2042.2001.00360.x11683972
|
|
10.
|
D EnglandL HochholzerM McCarthyLocalized
benign and malignant fibrous tumors of the pleura: a
clinicopathologic review of 223 casesAm J Surg
Pathol13640658198910.1097/00000478-198908000-000032665534
|
|
11.
|
SR GrobmyerRG MakiGD DemetriM MazumdarE
RiedelMF BrennanNeo-adjuvant chemotherapy for primary high-grade
extremity soft tissue sarcomaAnn
Oncol1516671672200410.1093/annonc/mdh43115520069
|
|
12.
|
GD DemetriS AntoniaRS BenjaminNCCN
Clinical Practice Guidelines in Oncology: Soft Tissue Sarcoma-V.
22009
|
|
13.
|
J De BoerPL JagerT WiggersP NieboerWAN
MachteldE PrasThe therapeutic challenge of a nonresectable solitary
fibrous tumor in a hypoglycemic patientInt J Clin
Oncol11478481200617180519
|
|
14.
|
M PrunottoM BoscoL DanieleL Macri’L
BonelloL SchirosiImatinib inhibits in vitro proliferation of cells
derived from a pleural solitary fibrous tumor expressing
platelet-derived growth factor receptor-betaLung
Cancer64244246200910.1016/j.lungcan.2008.10.013
|
|
15.
|
T De PasF ToffalorioP ColomboG TrifiròG
PelosiPD VignaBrief report: activity of imatinib in a patient with
platelet-derived-growth-factor receptor positive malignant solitary
fibrous tumor of the pleuraJ Thorac Oncol3938941200818670317
|
|
16.
|
SW WeissJR GoldblumSoft tissue tumors of
intermediate malignancy of uncertain typeSoft Tissue Tumor5th
editionMosby ElsevierPhiladephia109311602008
|
|
17.
|
AV Vallat-DecouvelaereSM DryCD
FletcherAtypical and malignant solitary fibrous tumors in
extrathoracic locations: evidence of their comparability to
intra-thoracic tumorsAm J Surg
Pathol2215011511199810.1097/00000478-199812000-00007
|
|
18.
|
LFJ GuillouCDM FletcherN
MandahiExtrapleural solitary fibrous tumour and
hemangiopericytomaWorld Health Organization Classification of
Tumours: Pathology and Genetics of Tumours of Soft Tissue and Bone.
Fletcher. CDMKK UnniF MertensIARC PressLyon86902002
|
|
19.
|
JM MosqueraCD FletcherExpanding the
spectrum of malignant progression in solitary fibrous tumors: a
study of 8 cases with a discrete anaplastic component - is this
dedifferentiated SFT?Am J Surg
Pathol3313141321200910.1097/PAS.0b013e3181a6cd3319718788
|
