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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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November 2012 Volume 4 Issue 5

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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

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International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

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Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

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Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

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Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

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Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

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International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

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International Journal of Epigenetics

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Article

Efficacy assessment of pemetrexed treatment of an NSCLC case with brain metastasis

  • Authors:
    • Jing Liang
    • Xiaolin Liu
    • Beibei Yin
    • Hairong Liu
    • Junjuan Xiao
    • Yan Li
  • View Affiliations / Copyright

    Affiliations: Department of Oncology, Qianfoshan Hospital, Shandong University, Jinan, Shandong 250014, P.R. China
  • Pages: 1119-1121
    |
    Published online on: August 30, 2012
       https://doi.org/10.3892/ol.2012.888
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Abstract

Non-small cell lung cancers (NSCLCs) are among the most common malignancies. Although pemetrexed is often used clinically to cure cancers, its efficacy in NSCLC patients with progressive brain metastases remains unclear. Here, we report a successful NSCLC (adenocarcinoma) case treated with pemetrexed. The detected tumors were treated with 900 mg of pemetrexed disodium (500 mg/m2) was administered to the patient on day 1, and 40 mg of cisplatin (25mg/m2) was administered on days 1-3, at the interval of 3 weeks. After two cycles of chemotherapy, the brain metastases were reduced. The lesion in the lung was reduced as determined by chest CT-scan. Our results suggest that pemetrexed is an effective therapy for patients with NSCLC and progressive brain metastases.
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Copy and paste a formatted citation
Spandidos Publications style
Liang J, Liu X, Yin B, Liu H, Xiao J and Li Y: Efficacy assessment of pemetrexed treatment of an NSCLC case with brain metastasis. Oncol Lett 4: 1119-1121, 2012.
APA
Liang, J., Liu, X., Yin, B., Liu, H., Xiao, J., & Li, Y. (2012). Efficacy assessment of pemetrexed treatment of an NSCLC case with brain metastasis. Oncology Letters, 4, 1119-1121. https://doi.org/10.3892/ol.2012.888
MLA
Liang, J., Liu, X., Yin, B., Liu, H., Xiao, J., Li, Y."Efficacy assessment of pemetrexed treatment of an NSCLC case with brain metastasis". Oncology Letters 4.5 (2012): 1119-1121.
Chicago
Liang, J., Liu, X., Yin, B., Liu, H., Xiao, J., Li, Y."Efficacy assessment of pemetrexed treatment of an NSCLC case with brain metastasis". Oncology Letters 4, no. 5 (2012): 1119-1121. https://doi.org/10.3892/ol.2012.888
Copy and paste a formatted citation
x
Spandidos Publications style
Liang J, Liu X, Yin B, Liu H, Xiao J and Li Y: Efficacy assessment of pemetrexed treatment of an NSCLC case with brain metastasis. Oncol Lett 4: 1119-1121, 2012.
APA
Liang, J., Liu, X., Yin, B., Liu, H., Xiao, J., & Li, Y. (2012). Efficacy assessment of pemetrexed treatment of an NSCLC case with brain metastasis. Oncology Letters, 4, 1119-1121. https://doi.org/10.3892/ol.2012.888
MLA
Liang, J., Liu, X., Yin, B., Liu, H., Xiao, J., Li, Y."Efficacy assessment of pemetrexed treatment of an NSCLC case with brain metastasis". Oncology Letters 4.5 (2012): 1119-1121.
Chicago
Liang, J., Liu, X., Yin, B., Liu, H., Xiao, J., Li, Y."Efficacy assessment of pemetrexed treatment of an NSCLC case with brain metastasis". Oncology Letters 4, no. 5 (2012): 1119-1121. https://doi.org/10.3892/ol.2012.888
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