1
|
Bosch FX, Ribes J, Cléries R, et al:
Epidemiology of hepatocellular carcinoma. Clin Liver Dis.
9:191–211. 2005. View Article : Google Scholar : PubMed/NCBI
|
2
|
Llovet JM and Bruix J: Novel advancements
in the management of hepatocellular carcinoma in 2008. J Hepatol.
48(Suppl 1): S20–37. 2008. View Article : Google Scholar : PubMed/NCBI
|
3
|
Gish RG, Porta C, Lazar L, et al: Phase
III randomized controlled trial comparing the survival of patients
with unresectable hepatocellular carcinoma treated with nolatrexed
or doxorubicin. J Clin Oncol. 25:3069–3075. 2007. View Article : Google Scholar : PubMed/NCBI
|
4
|
Cheng AL, Kang YK, Chen Z, et al: Efficacy
and safety of sorafenib in patients in the Asia-Pacific region with
advanced hepatocellular carcinoma: a phase III randomised,
double-blind, placebo-controlled trial. Lancet Oncol. 10:25–34.
2009. View Article : Google Scholar : PubMed/NCBI
|
5
|
Llovet JM, Ricci S, Mazzaferro V, et al:
Sorafenib in advanced hepatocellular carcinoma. N Engl J Med.
359:378–390. 2008. View Article : Google Scholar : PubMed/NCBI
|
6
|
Yoshida T, Hisamoto T, Akiba J, et al:
Spreds, inhibitors of the Ras/ERK signal transduction, are
dysregulated in human hepatocellular carcinoma and linked to the
malignant phenotype of tumors. Oncogene. 25:6056–6066. 2006.
View Article : Google Scholar : PubMed/NCBI
|
7
|
Huitzel-Melendez FD, Saltz LB, Song J, et
al: Retrospective analysis of outcome in hepatocellular carcinoma
(HCC) patients with hepatitis C (C+) versus B (B+) treated with
sorafenib (abstract). In: Presented at the 2007 ASCO
Gastrointestinal Cancers Symposium. (abstract 173); Orlando, FL.
2007;
|
8
|
Zhu AX: Predicting the response to
sorafenib in hepatocellular carcinoma: where is the evidence for
phosphorylated extracellular signaling-regulated kinase (pERK)? BMC
Med. 7:422009. View Article : Google Scholar : PubMed/NCBI
|
9
|
Strumberg D, Richly H, Hilger RA, et al:
Phase I clinical and pharmacokinetic study of the Novel Raf kinase
and vascular endothelial growth factor receptor inhibitor BAY
43-9006 in patients with advanced refractory solid tumors. J Clin
Oncol. 23:965–972. 2005. View Article : Google Scholar
|
10
|
Petrelli A and Giordano S: From single- to
multi-target drugs in cancer therapy: when aspecificity becomes an
advantage. Curr Med Chem. 15:422–432. 2008. View Article : Google Scholar : PubMed/NCBI
|
11
|
Abbadessa G, Rimassa L, Pressiani T, et
al: Optimized management of advanced hepatocellular carcinoma: four
long-lasting responses to sorafenib. World J Gastroenterol.
17:2450–2453. 2011. View Article : Google Scholar : PubMed/NCBI
|
12
|
Edeline J, Boucher E, Rolland Y, et al:
Comparison of tumor response by Response Evaluation Criteria in
Solid Tumors (RECIST) and modified RECIST in patients treated with
sorafenib for hepatocellular carcinoma. Cancer. 118:147–156. 2012.
View Article : Google Scholar
|
13
|
Milano A, Perri F, Ciarmiello A, et al:
Targeted-therapy and imaging response: a new paradigm for clinical
evaluation? Rev Recent Clin Trials. 6:259–265. 2011. View Article : Google Scholar : PubMed/NCBI
|
14
|
Horger M, Lauer UM, Schraml C, et al:
Early MRI response monitoring of patients with advanced
hepatocellular carcinoma under treatment with the multikinase
inhibitor sorafenib. BMC Cancer. 9:208–209. 2009. View Article : Google Scholar
|