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Oncology Letters
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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
January 2013 Volume 5 Issue 1

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Review

Targeted therapies in small cell lung cancer (Review)

Hong-Yang Lu, Xiao-Jia Wang, Wei-Min Mao
Pages: 3-11
Published online on: 06 July 2012

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Review

Updates on the cytogenetics and molecular cytogenetics of benign and intermediate soft tissue tumors (Review)

Jun Nishio
Pages: 12-18
Published online on: 30 October 2012

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Review

Role of epidermal growth factor receptor tyrosine kinase inhibitors in the treatment of esophageal carcinoma and the suggested mechanisms of action (Review)

Yaping Xu, Liming Sheng, Weimin Mao
Pages: 19-24
Published online on: 24 October 2012

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Article

Analysis of APC and IGFBP7 promoter gene methylation in Swedish and Vietnamese colorectal cancer patients

Jan Dimberg, Thai Trinh Hong, Marita Skarstedt, Sture  Löfgren, Niklas Zar, Andreas Matussek
Pages: 25-30
Published online on: 12 October 2012

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Article

Superficial spreading squamous cell carcinoma of the uterine cervix involving the endometrium: Report of two cases with emphasis on the likely molecular mechanism

Mitsuaki Ishida, Hidetoshi Okabe
Pages: 31-34
Published online on: 03 October 2012

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Article

Pegylated liposomal doxorubicin for platinum-resistant or refractory Müllerian carcinoma (epithelial ovarian carcinoma, primary carcinoma of Fallopian tube and peritoneal carcinoma): A single-institutional experience

Takeshi Fukuda, Toshiyuki Sumi, Masatomo Teramae, Yusuke  Nakano, Masanari Morishita, Hiroyuki Terada, Hiroyuki Yoshida, Yoshinari Matsumoto, Tomoyo Yasui, Osamu Ishiko
Pages: 35-38
Published online on: 16 October 2012

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Article

DNA hypomethylation of interleukin 8 in clear cell renal cell carcinoma

Koo Han Yoo, Yong-Koo Park, Sung-Goo Chang
Pages: 39-42
Published online on: 24 October 2012

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Article

Involvement of the phosphoinositide 3‑kinase/Akt pathway in apoptosis induced by capsaicin in the human pancreatic cancer cell line PANC-1

Jian-Hong Zhang, Fu-Ji Lai, Hui Chen, Jiang Luo, Ri-Yuan Zhang, He‑Qi  Bu, Zhao-Hong Wang, Hong-Hai Lin, Sheng-Zhang Lin
Pages: 43-48
Published online on: 24 October 2012

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Article

Sarcomatoid variant of urothelial carcinoma: Cytological analysis of three cases

Namie Arita, Mitsuaki Ishida, Keiko Yoshida, Akiko Kagotani, Nozomi Iwamoto, Muneo Iwai, Hidetoshi Okabe
Pages: 49-52
Published online on: 24 October 2012

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Article

Small cell carcinoma of the prostate after high-dose-rate brachytherapy for low-risk prostatic adenocarcinoma

Akira Komiya, Kenji Yasuda, Tetsuo Nozaki, Yasuyoshi  Fujiuchi, Shin-Ichi Hayashi, Hideki Fuse
Pages: 53-56
Published online on: 25 October 2012

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Article

Clinical features of intracranial vestibular schwannomas

Xiang Huang, Jian Xu, Ming Xu, Liang‑Fu Zhou, Rong Zhang, Liqin Lang, Qiwu Xu, Ping Zhong, Mingyu Chen, Ying Wang, Zhenyu Zhang
Pages: 57-62
Published online on: 31 October 2012

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Article

Concomitant intraductal papillary mucinous neoplasm and neuroendocrine tumor of the pancreas

Mitsuaki Ishida, Hisanori Shiomi, Shigeyuki Naka, Tohru Tani, Hidetoshi Okabe
Pages: 63-67
Published online on: 03 October 2012

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Article

Sorafenib combined with gemcitabine in EGFR‑TKI‑resistant human lung cancer cells

Jing Li, Yue-Yin Pan, Ying Zhang
Pages: 68-72
Published online on: 09 October 2012

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Case Report

CD8+ mycosis fungoides with esophageal involvement: A case report

Mitsuaki Ishida, Yosuke Mochizuki, Yasuharu Saito, Yoshihide  Fujiyama, Keiko Hodohara, Takashi Yoshida, Hidetoshi Okabe
Pages: 73-75
Published online on: 16 October 2012

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Article

Promoting effect of arachidonic acid supplementation on N‑methyl‑N‑nitrosourea-induced pancreatic acinar cell hyperplasia in young Lewis rats

Katsuhiko Yoshizawa, Norihisa Uehara, Ayako Kimura, Yuko Emoto, Yuichi Kinoshita, Takashi Yuri, Hideho Takada, Toru  Moriguchi, Tomohito Hamazaki, Airo Tsubura
Pages: 76-82
Published online on: 31 October 2012

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Article

Analysis of complete response by MRI following neoadjuvant chemotherapy predicts pathological tumor responses differently for molecular subtypes of breast cancer Corrigendum in /ol/5/4/1433

Yuji Hayashi, Hiroyuki Takei, Satoshi Nozu, Yoshihiro Tochigi, Akihiro  Ichikawa, Naoki Kobayashi, Masafumi Kurosumi, Kenichi Inoue, Takashi Yoshida, Shigenori  E. Nagai, Hanako Oba, Toshio Tabei, Jun Horiguchi, Izumi Takeyoshi
Pages: 83-89
Published online on: 30 October 2012

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Article

Synergistic effects of soluble PD-1 and IL-21 on antitumor immunity against H22 murine hepatocellular carcinoma

Xiu-Cheng Pan, Li Li, Juan-Juan Mao, Wei Yao, Jun-Nian Zheng, Mei Liu, Juan-Juan Fu
Pages: 90-96
Published online on: 12 October 2012

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Case Report

Primary inflammatory myofibroblastic tumor of the breast with rapid recurrence and metastasis: A case report

Hua-Dong Zhao, Tao Wu, Jun-Qing Wang, Wen-Dong Zhang, Xian‑Li He, Guo-Qiang Bao, Yi Li, Li Gong, Qing Wang
Pages: 97-100
Published online on: 01 October 2012

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Article

Role of Ku70 and Bax in epigallocatechin-3-gallate‑induced apoptosis of A549 cells in vivo

Li Jing-Jing, Gu Qi-Hua, Li Min, Yang Hua-Ping, Cao Li-Ming, Hu Cheng-Ping
Pages: 101-106
Published online on: 16 October 2012

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Article

Annexin A1, A2, A4 and A5 play important roles in breast cancer, pancreatic cancer and laryngeal carcinoma,alone and/or synergistically

Shishan Deng, Jianguo Wang, Lingmi Hou, Jinsui Li, Guo  Chen, Baoqian Jing, Xiaoming Zhang, Zhengwei Yang
Pages: 107-112
Published online on: 09 October 2012

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Article

Expression pattern of polypeptide N-acetylgalactosaminyltransferase-10 in gastric carcinoma

Yuan Gao, Zhenhua Liu, Jinghua Feng, Qizhe Sun, Bao Zhang, Wenling Zheng, Wenli Ma
Pages: 113-116
Published online on: 19 October 2012

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Case Report

Second-line chemotherapy for refractory small cell neuroendocrine carcinoma of the esophagus that relapsed after complete remission with irinotecan plus cisplatin therapy: Case report and review of the literature

Shinsuke Funakoshi, Akinori Hashiguchi, Kana Teramoto, Naoteru Miyata, Satoshi Kurita, Masayuki Adachi, Yasuo Hamamoto, Hajime  Higuchi, Hiromasa Takaishi, Toshifumi Hibi
Pages: 117-122
Published online on: 30 October 2012

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Article

A huge malignant peripheral nerve sheath tumor with hepatic metastasis arising from retroperitoneal ganglioneuroma

Z. H. Meng, Y. S. Yang, K. L. Cheng, G. Q. Chen, L. P. Wang, W. Li
Pages: 123-126
Published online on: 10 October 2012

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Article

The pan‑deacetylase inhibitor panobinostat modulates the expression of epithelial‑mesenchymal transition markers in hepatocellular carcinoma models

Pietro Di Fazio, Roberta Montalbano, Karl Quint, Beate Alinger, Ralf Kemmerling, Tobias Kiesslich, Matthias Ocker, Daniel Neureiter
Pages: 127-134
Published online on: 01 October 2012

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Article

Histological evaluation of bone biopsy results during PVP or PKP of vertebral compression fractures

Lei Zhang, Jigang Li, Huilin Yang, Zongping Luo, Jun Zou
Pages: 135-138
Published online on: 28 September 2012

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Article

Response‑specific progestin resistance in a newly characterized Ishikawa human endometrial cancer subcell line resulting from long‑term exposure to medroxyprogesterone acetate

Shujun Zhao, Genxia Li, Li Yang, Lei Li, Hongyu Li
Pages: 139-144
Published online on: 17 October 2012

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Article

Expression of cyclin E in stage III colorectal carcinoma

Lea Rath-Wolfson, Michael Bergman, Yaacov Ori, Alex Goldman, Edward Ram, Rumelia Koren, Hertzel Salman
Pages: 145-148
Published online on: 05 October 2012

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Article

Epithelial-mesenchymal transition expression profiles as a prognostic factor for disease-free survival in hepatocellular carcinoma: Clinical significance of transforming growth factor-β signaling

Kosuke Mima, Hiromitsu Hayashi, Hideyuki Kuroki, Shigeki Nakagawa, Hirohisa  Okabe, Akira Chikamoto, Masayuki Watanabe, Toru Beppu, Hideo Baba
Pages: 149-154
Published online on: 05 October 2012

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Article

Molecular characterisation of gastrointestinal stromal tumours in a South African population

Gillian Baker, Chantal Babb, Desmond Schnugh, Simon Nayler, Melanie Louw, Jacqueline Goedhals, Pierre-Paul Bringuier, Jean-Yves Blay, Pascale Willem
Pages: 155-160
Published online on: 05 November 2012

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Article

Cytoplasmic expression of p33ING1b is correlated with tumorigenesis and progression of human esophageal squamous cell carcinoma

Zhen-Long Zhu, Bao-Yong Yan, Yu Zhang, Yan-Hong Yang, Zheng-Min Wang, Hong-Zhen Zhang, Ming-Wei Wang, Xiang-Hong Zhang, Xiao-Feng Sun
Pages: 161-166
Published online on: 22 October 2012

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Article

Rapamycin induces autophagy in the melanoma cell line M14 via regulation of the expression levels of Bcl‑2 and Bax

Xue Li, Di Wu, Jinggang Shen, Meihua Zhou, Yan Lu
Pages: 167-172
Published online on: 22 October 2012

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Article

Single nucleotide polymorphism array analysis of microsatellite-stable, diploid/near-diploid colorectal carcinomas without the CpG island methylator phenotype

Michael Linnebacher, Christiane Ostwald, Dirk Koczan, Tareq Salem, Björn Schneider, Mathias Krohn, Mathias Ernst, Friedrich Prall
Pages: 173-178
Published online on: 30 October 2012

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Article

Mesenchymal stem-like cells isolated from human esophageal carcinoma and adjacent non-cancerous tissues

Jiabo Hu, Zhongwei Zhou, Shunbin Shi, Xiaozhong Zhu, Xiaohui Wang, Wei Zhang, Sanqiang Hu, Hui Qian, Wenrong Xu
Pages: 179-184
Published online on: 30 October 2012

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Article

Factors influencing the risk of recurrence in patients with esophageal carcinoma treated with surgery: A single institution analysis consisting of 1002 cases

Yaping Xu, Qixun Chen, Xinmin Yu, Ximing Zhou, Xiao Zheng, Weimin Mao
Pages: 185-190
Published online on: 30 October 2012

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Article

Carbonic anhydrase IX is a clinically significant tissue and serum biomarker associated with renal cell carcinoma

Martina Takacova, Maria Bartosova, Lucia Skvarkova, Miriam Zatovicova, Ivana Vidlickova, Lucia Csaderova, Monika Barathova, Jan Breza, Peter  Bujdak, Jaromir Pastorek, Silvia Pastorekova
Pages: 191-197
Published online on: 26 October 2012

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Article

Medical thoracoscopy and gastroscopy for the treatment of intrathoracic anastomotic leakage following esophagectomy

Xiao-Hai Li, Yi Hu, Tie-Hua Rong, Xiao-Dong Li, Xiao‑Dong  Su, Hong Yang, Amos Ela Bella, Jian-Hua Fu
Pages: 198-200
Published online on: 08 October 2012

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Article

Expression and clinical significance of extracellular matrix metalloproteinase inducer, EMMPRIN/CD147, in human osteosarcoma

Qiang Lu, Gang Lv, Andre Kim, Jong‑Myung Ha, Suhkman Kim
Pages: 201-207
Published online on: 19 October 2012

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Article

Tendencies for higher co-expression of EGFR and HER2 and downregulation of HER3 in prostate cancer lymph node metastases compared with corresponding primary tumors

J. Carlsson, L. Shen, J. Xiang, J. Xu, Q. Wei
Pages: 208-214
Published online on: 25 October 2012

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Case Report

Papillary thyroid carcinoma with fibromatosis‑like stroma: A case report and review of the literature

Zhiming Wu, Xiufeng Chu, Shenglong Fan, Xingcheng Meng, Chaoyang Xu
Pages: 215-217
Published online on: 24 October 2012

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Case Report

Gastrointestinal bleeding as an initial manifestation in asymptomatic multiple myeloma: A case report and review of the literature

Maosong Lin, Jiayi Zhu, Hongzhang Shen, Junxing Huang
Pages: 218-220
Published online on: 01 October 2012

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Article

Expression of β-adrenergic receptors in pediatric malignant brain tumors

Iacopo Sardi, Laura Giunti, Cecilia Bresci, Anna Maria Buccoliero, Duccio Degl'innocenti, Stefania Cardellicchio, Gianna Baroni, Francesca Castiglione, Martina Da Ros, Patrizio Fiorini, Sabrina  Giglio, Lorenzo Genitori, Maurizio Aricò, Luca Filippi
Pages: 221-225
Published online on: 23 October 2012

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Article

A case of congenital giant gallbladder with massive hydrops mimicking celiac cyst

Liang Zong, Ping Chen, Lei Wang, Chunlan He, Guangyao Wang, Jian Jiang, Hao Wang
Pages: 226-228
Published online on: 31 October 2012

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Article

Expression analysis and clinical significance of CXCL16/CXCR6 in patients with bladder cancer

Jun Taik Lee, Sang Don Lee, Jeong Zoo Lee, Moon Kee Chung, Hong Koo Ha
Pages: 229-235
Published online on: 17 October 2012

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Case Report

Synchronous nasopharyngeal carcinoma and cardia adenocarcinoma accompanied with suspected dermatomyositis: A case report and literature review

Rui Ao, Yuhui Wang, Dandan Dong, Ke Xie, Zhengrong Wang
Pages: 236-238
Published online on: 11 October 2012

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Article

Jejunal intussusception and polyps with different types of malignant transformation in Peutz‑Jeghers syndrome: Report of a case

Hongke Cai, Wei Tian, Meiqi Zhou, Haifei He, Yue Hu, Yongchuan Deng
Pages: 239-241
Published online on: 23 October 2012

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Article

The triterpenoid pristimerin induces U87 glioma cell apoptosis through reactive oxygen species-mediated mitochondrial dysfunction

Yan-Yan Yan, Jian-Ping Bai, Yong Xie, Jie-Zhong Yu, Cun-Gen Ma
Pages: 242-248
Published online on: 22 October 2012

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Article

Comparison of KRAS/BRAF mutations between primary tumors and serum in colorectal cancer: Biological and clinical implications

Xingxiang Pu, Zhizhong Pan, Ying Huang, Ying Tian, Hongqiang Guo, Lin Wu, Xuexing He, Xinggui Chen, Shaodan Zhang, Tongyu Lin
Pages: 249-254
Published online on: 10 October 2012

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Article

RhoGDI2 confers resistance to 5-fluorouracil in human gastric cancer cells

Zhong Zheng, Xiang-Yi He, Jian-Fang Li, Bei-Qin Yu, Xue-Hua Chen, Jun  Ji, Jia-Nian Zhang, Qin-Long Gu, Zheng-Gang Zhu, Bing-Ya Liu
Pages: 255-260
Published online on: 01 October 2012

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Article

Expression and significance of hypoxia-inducible factor‑1α and glucose transporter-1 in laryngeal carcinoma Corrigendum in /ol/6/1/287

Xiao-Hong Wu, Su-Ping Chen, Jian-Ying Mao, Xue‑Xian  Ji, Hong-Tian Yao, Shui-Hong Zhou
Pages: 261-266
Published online on: 26 September 2012

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Article

Clinicopathological characteristics of patients with synchronous primary endometrial and ovarian cancers: A review of 43 cases

Yuantao Liu, Jun Li, Hongyan Jin, Ying Lu, Xin Lu
Pages: 267-270
Published online on: 27 September 2012

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Article

Clinical investigation of EGFR mutation detection by pyrosequencing in lung cancer patients

Hee Joung Kim, Seo Young Oh, Wan Seop Kim, Sun Jong Kim, Gwang Ha Yoo, Won Dong Kim, Kye Young Lee
Pages: 271-276
Published online on: 01 October 2012

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Article

The CXCL12/CXCR4 autocrine loop increases the metastatic potential of non-small cell lung cancer in vitro

Xiaofeng Dai, Zhifu Mao, Songping Xie, Hao Zhang, Jie Huang
Pages: 277-282
Published online on: 10 October 2012

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Article

Mismatch repair hMSH2, hMLH1, hMSH6 and hPMS2 mRNA expression profiles in precancerous and cancerous urothelium

Dimitra P. Vageli, Stavros Giannopoulos, Sotirios G. Doukas, Christos Kalaitzis, Stilianos Giannakopoulos, Alexandra Giatromanolaki, George K. Koukoulis, Stavros Touloupidis
Pages: 283-294
Published online on: 19 October 2012

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Article

Accurate breast cancer diagnosis through real-time PCR her‑2 gene quantification using immunohistochemically-identified biopsies

Gretel Mendoza, Amelia Portillo, Jorge Olmos‑Soto
Pages: 295-298
Published online on: 22 October 2012

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Article

Elevated preoperative plasma D‑dimer levels and the incidence of venous thromboembolism in Japanese females with gynecological cancer

Junichi Kodama, Noriko Seki, Chikako Fukushima, Tomoyuki Kusumoto, Keiichiro Nakamura, Atsushi Hongo, Yuji Hiramatsu
Pages: 299-304
Published online on: 15 October 2012

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Article

Anticancer potential of an ethanol extract of Asiasari radix against HCT-116 human colon cancer cells in vitro

Se-Mi Oh, Jinhee Kim, Jun Lee, Jin-Mu Yi, Dal-Seok Oh, Ok-Sun Bang, No Soo Kim
Pages: 305-310
Published online on: 01 November 2012

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Article

Prospective evaluation of cisplatin- and carboplatin‑mediated ototoxicity in paediatric and adult soft tissue and osteosarcoma patients

Alexandra Nitz, Evangelos Kontopantelis, Stefan Bielack, Ewa Koscielniak, Thomas Klingebiel, Thorsten Langer, Marios Paulides
Pages: 311-315
Published online on: 25 October 2012

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Article

Plasma levels of matrix metalloproteinases 2 and 9 correlate with histological grade in breast cancer patients

Fortunata Vasaturo, Fabiana Solai, Carolina Malacrino, Tiziana Nardo, Bruno Vincenzi, Mauro Modesti, Susanna Scarpa
Pages: 316-320
Published online on: 17 October 2012

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Article

Predictive markers for the response to 5-fluorouracil therapy in cancer cells: Constant-field gel electrophoresis as a tool for prediction of response to 5-fluorouracil-based chemotherapy

E. M. Saleh, R. A. El-Awady, N. Anis
Pages: 321-327
Published online on: 11 October 2012

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Case Report

Breast metastasis from a pulmonary adenocarcinoma: Case report and review of the literature Retraction in /10.3892/ol.2019.10965

Alessandro Sanguinetti, Francesco Puma, Roberta Lucchini, Stefano Santoprete, Roberto Cirocchi, Alessia Corsi, Roberta Triola, Nicola Avenia
Pages: 328-332
Published online on: 25 October 2012

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Case Report

Unilateral multicentric cancer of the breast containing two different histopathological types: Case report

Tadahiro Nozoe, Katsuo Sueishi, Emiko Mori, Mayuko Kohno, Tomohiro Iguchi, Takashi Maeda, Takahiro Ezaki
Pages: 333-335
Published online on: 05 October 2012

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Article

Polymorphisms in bone morphogenetic protein 3 and the risk of papillary thyroid cancer

Young Ock Kim, Il Ki Hong, Young Gyu Eun, Seong‑Su Nah, Soojeong Lee, Su‑Hak Heo, Hyung-Kee Kim, Ho‑Yeon Song, Hak‑Jae Kim
Pages: 336-340
Published online on: 10 October 2012

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Piceatannol inhibits MMP-9-dependent invasion of tumor necrosis factor-α-stimulated DU145 cells by suppressing the Akt-mediated nuclear factor-κB pathway

Rajapaksha Gendara Prasad Tharanga Jayasooriya, Yong-Gab Lee, Chang-Hee Kang, Kyoung-Tae Lee, Yung Hyun Choi, Sung-Yong Park, Jae-Kwan Hwang, Gi-Young Kim
Pages: 341-347
Published online on: 12 October 2012

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Adenovirus-mediated combined anti-angiogenic and pro-apoptotic gene therapy enhances antitumor efficacy in hepatocellular carcinoma

Fei Yan, Yi Zheng, Laiqiang Huang
Pages: 348-354
Published online on: 23 October 2012

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Article

Characteristics of recurrence after radical esophagectomy with two-field lymph node dissection for thoracic esophageal cancer

Cheng-Lin Li, Fu-Li Zhang, Ya-Di Wang, Chun Han, Guo-Gui Sun, Qing Liu, Yun-Jie Cheng, Shao-Wu Jing, Cong-Rong Yang
Pages: 355-359
Published online on: 01 October 2012

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Case Report

Sporadic renal haemangioblastoma: Case report and review of the literature

Yadong Wang, Can Wei, Lisha Mou, Qiang Zhang, Zhiwen  Cui, Xianxin Li, Jiongxian Ye, Yongqing Lai
Pages: 360-362
Published online on: 27 September 2012

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Article

Assessment of the feeding arteries by three-dimensional computed tomography angiography prior to multi‑arterial infusion chemotherapy for lung cancer

Xiao-Dan Ye, Zheng Yuan, Jian-Ding Ye, Xiang-Sheng Xiao
Pages: 363-367
Published online on: 26 October 2012

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Article

Differential expression of the Na+/I‑ symporter protein in thyroid cancer and adjacent normal and nodular goiter tissues

Shasha Wang, Jun Liang, Yansong Lin, Ruyong Yao
Pages: 368-372
Published online on: 01 October 2012

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Article

Transducer of erbB2.1 is a potential cellular target of gefitinib in lung cancer therapy

Ke‑Kang Sun, Yang Yang, Lin Zhao, Li‑Li Wang, Yang Jiao
Pages: 373-377
Published online on: 15 October 2012

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Case Report

Giant non-functional adrenal adenoma: A case report

Baozhong Li, Qingqu Guo, Haijun Yang, Jianyun Guan
Pages: 378-380
Published online on: 19 October 2012

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Case Report

Long-term progression-free survival in a case of hepatocellular carcinoma with vertebral metastasis treated with a reduced dose of sorafenib: Case report and review of the literature

Juan Du, Xiaoping Qian, Baorui Liu
Pages: 381-385
Published online on: 17 October 2012

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Article

Pomolic acid induces apoptosis in SK-OV-3 human ovarian adenocarcinoma cells through the mitochondrial-mediated intrinsic and death receptor-induced extrinsic pathways

Ki Hyun Yoo, Jong-Hwa Park, Do Kyung Lee, Yuan Yuan Fu, Nam In Baek, In Sik Chung
Pages: 386-390
Published online on: 22 October 2012

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Comparison of distribution characteristics of metastatic bone lesions between breast and prostate carcinomas

Chang-Yin Wang, Guang-Yao Wu, Mei-Juan Shen, Kun-Wei Cui, Ying Shen
Pages: 391-397
Published online on: 30 October 2012

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Article

Functional variants at the miRNA binding sites of the E2F1 gene and its mRNA expression

Yunzhao Zhao, Lin Tang, Weiwei Nie, Zexing Wang, Xiaoxiang Guan
Pages: 398-402
Published online on: 26 October 2012

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January-2026 Volume 31 Issue 1

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Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

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Predictive analysis of BRAF V600E mutation and central lymph node metastasis in papillary thyroid carcinoma

Junhui Peng, Zhihui Wu, Yujun Huang, Runhua Pan, Zhongdai Fu, Jianzhang Wang
Article Number: 44
Published online on: 24 November 2025

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Adverse events induced by the subcutaneous HER2-targeted antibody‑drug conjugate JSKN033 in a male patient with breast cancer: A case report

Rui Yang, Jian Zhang, Yang Wang
Article Number: 43
Published online on: 24 November 2025

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Prediction of solitary ≤3‑cm small adrenal metastasis based on 18F‑FDG PET/CT using a support vector machine model in lung cancer

Lin Zhao, Haifeng Cai, Jingwu Li, Wenzhe Zhao, Yongliang Liu, Lixiu Cao
Article Number: 42
Published online on: 24 November 2025

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Transferrin receptor serves a role in promoting PANoptosis in thyroid cancer

Shungao Ma, Zhiqiang Ma, Jingwei Shen, Hong Liu, Hua Yang, Yuqin Hu, Simeng Ying
Article Number: 41
Published online on: 24 November 2025

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Oxidative stress as a nexus: Integrating mitophagy and ferroptosis in endometrial carcinogenesis (Review)

Qixia Yu, Liangxin Ren, Feng Ren, Fengling Li
Article Number: 40
Published online on: 20 November 2025

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Astragalin: A promising herbal compound with broad anticancer potential (Review)

Yu-Qian Fu, Chan Li, Dan-Ni Ding, Fang-Yuan Liu, Yu-Fei Zhu, Feng-Juan Han
Article Number: 39
Published online on: 20 November 2025

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Analysis of prognostic factors influencing brain metastasis in EGFR‑mutant lung adenocarcinoma and comparison of prognostic assessment models

Junjun Miao, Jianwei Hu, Yongxia Zhang, Lei Gao, Xiangkun Yuan
Article Number: 38
Published online on: 18 November 2025

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Case Report

Fumarate hydratase-deficient renal cell carcinoma arising in acquired cystic kidney disease in a hemodialysis patient: Diagnostic clues from percutaneous renal mass core needle biopsy: A case report

Yuki Oba, Hisashi Kamido, Kei Kono, Katsuyuki Miki, Shinji Ito, Akinari Sekine, Shigekazu Kurihara, Masayuki Yamanouchi, Tatsuya Suwabe, Yutaka Takazawa, Kenichi Ohashi, Yoji Nagashima, Yuki Nakamura, Yoshifumi Ubara, Naoki Sawa
Article Number: 37
Published online on: 18 November 2025

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TIMP1 expression in colorectal cancer: Linking prognosis, tumor immunity and molecular pathways

Jiming Gu, Dongming Zhu, Fan Chen, Tongguo Shi, Suhua Xia
Article Number: 36
Published online on: 18 November 2025

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[Retracted] Exosomes from LNCaP cells promote osteoblast activity through miR‑375 transfer

Su-Liang Li, Na An, Bing Liu, Sheng-Yu Wang, Jian-Jun Wang, Yun Ye
Article Number: 35
Published online on: 17 November 2025

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Article

TAS‑102 plus bevacizumab as salvage treatment in colorectal cancer: A retrospective study

Keita Matsumoto, Ryoma Yokoi, Chika Mizutani, Ryuichi Asai, Jesse Yu Tajima, Masahide Endo, Yuji Hatanaka, Takeshi Horaguchi, Masahiro Fukada, Itaru Yasufuku, Yuta Sato, Yoshihiro Tanaka, Katsutoshi Murase, Nobuhisa Matsuhashi
Article Number: 34
Published online on: 14 November 2025

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Research progress on neutrophil extracellular traps and hepatitis‑to‑hepatocellular carcinoma transformation (Review)

Yiwei Wang, Chengyan Zhang, Haonan Wang, Yali Zhou, Yuanbo Yu, Hui Liu, Chuansha Gu
Article Number: 33
Published online on: 14 November 2025

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Case Report Open Access

Remarkable response to Osimertinib plus Gumarontinib for EGFR mutation and concomitant MET exon 14 skipping in a patient with lung adenocarcinoma: A case report

Xuquan Jing, Li Li, Shuangqing Lu, Xiaoyang Zhai, Hui Zhu
Article Number: 32
Published online on: 12 November 2025

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Machine learning‑based signature for prognosis and drug sensitivity in hepatocellular carcinoma using glycolysis‑related gene

Yufan Zhou, Wei Liu, Zhixue Fang, Ke Zhou, Xing Huang, Shanzheng Lu, Weilin Zhang, Qiaocheng Wen, Xu Chen, Zhigang Xiao
Article Number: 31
Published online on: 12 November 2025

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Dual immune checkpoint inhibitor cardonilumab induces immune myocarditis in a patient with cancer‑related myocardial metastasis: A case report

Tianxing Liu, Qiang Li, Renya Zeng, Baidong Zhang, Zhichao Kang, Pengfei Zhang, Zhe Yang
Article Number: 30
Published online on: 12 November 2025

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Retrospective analysis of clinical characteristics, treatment outcomes and prognosis of patients with natural killer/T‑cell lymphoma

Pengye Li, Geraldine Esther Awakossa, Lu Zhou, Qiuhui Li, Xinxiu Liu, Fang Zhu, Tao Liu, Liling Zhang
Article Number: 29
Published online on: 11 November 2025

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From mechanism to targeted therapy: Advances in histone lactylation‑driven cancer progression (Review)

Zhe Jia, Shan Lu, Zhenchuan Wang, Pengfei Ge
Article Number: 28
Published online on: 11 November 2025

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[Retracted] Upregulation of cervical carcinoma expressed PCNA regulatory long non‑coding RNA promotes esophageal squamous cell carcinoma progression

Xiaojun Wang, Liangfen Zhou, Huiyun Zhang, Hui Ou, Wenxing Long, Xiaobao Liu
Article Number: 27
Published online on: 10 November 2025

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Biology of PEST‑containing nuclear proteins as potential targets in ovarian cancer (Review)

Hao Liu, Zhi-Liang Jiang, Yi Liu, Yong-Hao Zhu, Muhammad Usman Akbar, Saadullah Khattak, Zhendong Lu, Muhammad Babar Khawar, Yue Zhang, Umair Ali Khan Saddozai, Xin-Ying Ji
Article Number: 26
Published online on: 07 November 2025

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Article

Survival outcomes and prognostic factors in temporal bone malignancies: A retrospective cohort of 20 patients

Liming Gao, Wenyang Zhang, Ting Ye, Rui Guo, Yin Xia
Article Number: 25
Published online on: 06 November 2025

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Real‑world performance of the machine learning‑based prediction of chemotherapy‑associated adverse effects in lung cancer

Sha Huang, Zhengwei Huang, Zhoujian Sun, Tianao Xie, Xingyu Zhu, Sheng Lu, Zhengxing Huang, Jian Hu, Zhengfu He
Article Number: 24
Published online on: 06 November 2025

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Long non‑coding RNA RP11‑196G11.6 inhibits neuroblastoma progression by regulating the miR‑376a‑3p/RYBP signaling axis

Jie Zhang, Kai Huang, Jianwu Zhou, Wenge Liao, Fei Li, Zhenzhen Zhao, Shan Wang
Article Number: 23
Published online on: 06 November 2025

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Cervical cancer immune microenvironment: Mechanisms of HPV‑mediated immune evasion and advances in immunotherapy (Review)

Xiaojing Zhou, Ren An, Xiangjuan Li
Article Number: 22
Published online on: 05 November 2025

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Mesenchymal stem cell‑derived exosomes: Regulators of progression and suppression in pancreatic cancer (Review)

Haoyan Zhuang, Xuewen Shi
Article Number: 21
Published online on: 04 November 2025

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Advancements in research regarding the influence of the tumor microenvironment on the proliferation and metastasis of osteosarcoma (Review)

Tao Shi, Jianping Kang, Qiyang Wang, Jiamei Song, Xiaofeng He
Article Number: 20
Published online on: 04 November 2025

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Article Open Access

Enhanced expression of CXCL1 in renal cell carcinoma facilitates tumor cell malignancy via PI3K/AKT‑dependent mechanisms

Shiliang Gui, Hongrui Zhang, Huiting Xiao, Chen Liu, Yuhang Wang, Baotian Wang, Hongbin Qiu
Article Number: 19
Published online on: 03 November 2025

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Case Report Open Access

Photodynamic therapy with local‑targeted perfusion for recurrent tracheal adenoid cystic carcinoma achieving 12‑year survival: A case report

Luoqi Yang, Lu Wang, Hongwu Wang, Heng Zou
Article Number: 18
Published online on: 03 November 2025

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Retraction Open Access

[Retracted] Tunicamycin inhibits progression of glioma cells through downregulation of the MEG‑3‑regulated wnt/β‑catenin signaling pathway

Xin Li, Lei Xue, Qin Peng
Article Number: 17
Published online on: 03 November 2025

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Article Open Access

Non‑targeted metabolomics reveals diagnostic biomarker in the plasma of patients with lung cancer

Yan Liu, Yangmin Li, Haijun Hou, Yanyan Dong, Haitong Tian, Yanan Zhao, Ke Li, Jiayuan Zhou, Fujie Song, Yan Li
Article Number: 16
Published online on: 31 October 2025

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Primary pulmonary angiosarcoma: A case study with genetic insights and potential therapeutic targets

Yanling Zhu, Chunfang Guo
Article Number: 15
Published online on: 31 October 2025

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Progress in the treatment of esophageal neuroendocrine carcinoma (Review)

Jie Shi, Bin He, Heng Di Zhang, Chao Yang Jiang, Ling Zhang
Article Number: 14
Published online on: 31 October 2025

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Article Open Access

Sensitive cell‑free DNA assay for accurate detection of RAS and BRAF mutations in liquid biopsies of patients with metastatic colorectal cancer: Final results of the multicentric ColoBEAM study

Alexandre Harlé, Céline Gavoille, Olivier Bouché, Meher Ben Abdelghani, Jérome Plaza, Dominique Spaeth, Axelle Boudrant, François Ghiringhelli, Anne-Laure Villing, Christophe Borg, Marie Rouyer, Marie Husson, Pauline Gilson, Julia Salleron, Aurélien Lambert, Jean-Louis Merlin
Article Number: 13
Published online on: 30 October 2025

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Article

Single‑center retrospective study of factors associated with early discontinuation of tumor‑treating fields therapy in glioblastoma

Kohei Suzuki, Koichiro Sato, Shohei Nagasaka, Ryo Miyaoka, Takeshi Saito, Yoshiteru Nakano, Nayuta Higa, Toshiaki Akahane, Akihide Tanimoto, Ryosuke Hanaya, Junkoh Yamamoto
Article Number: 12
Published online on: 29 October 2025

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Clinical value of emerging peripheral blood protein biomarkers in prostate cancer (Review)

Mengli Chen, Feng Wang, Weixi Wang, Kangle Feng, Kaihua Xiang, Xubo Gong, Zhihua Tao, Weiwei Liu
Article Number: 11
Published online on: 29 October 2025

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Intratumoral and peritumoral radiomics of MRI predict pathological differentiation in patients with rectal cancer

Huanhui Liu, Hanjing Zhang, Qian Zou, Jianquan Yang
Article Number: 10
Published online on: 29 October 2025

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Retraction Open Access

[Retracted] Peritumoral activated hepatic stellate cells are associated with hepatic recurrence for resectable colorectal adenocarcinoma liver metastasis following resection

Li Deng, Taiyuan Li, Yuanyuan Liao, Shuang Liu, Zhen Xie, Zhixiang Huang, Hua Dai, Jianfeng Li, Xiong Lei
Article Number: 9
Published online on: 27 October 2025

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Case Report Open Access

Combined BRAF/MEK inhibition for BRAF‑mutant melanoma brain metastases in pregnancy: A case report

Jaroslav Melus, Michaela Jezberova, Silvia Mikulajova, Katarina Komaromy Gerincova, Martin Karlik, Igor Straka, Marek Krivosik, Peter Valkovic, Gabriela Timarova
Article Number: 8
Published online on: 24 October 2025

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Case Report Open Access

Synchronous rectal and endometrial cancer: A case report and literature review

Zhuofan Li, Li Peng, Qing Su, Beige Zong
Article Number: 7
Published online on: 24 October 2025

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Article

Predictive significance of thoracic skeletal muscle nutritional status for radiotherapy survival in elderly patients with esophageal squamous cell carcinoma

Shuqin Liu, Qi Li, Dongmei Luo, Caixia Jia, Dingqiang Peng, Guihong Liu
Article Number: 6
Published online on: 24 October 2025

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Review Open Access

Ribosome‑binding protein 1: A multidimensional regulator of cancer progression and a novel target for precision therapy (Review)

Ho Huang, Jia Ouyang
Article Number: 5
Published online on: 23 October 2025

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Case Report Open Access

Brain metastasis of ovarian cancer >20 years after initial diagnosis: A case report

Chihiro Ishizawa, Kazunari Miyazawa, Misaki Tani, Kazuaki Neriishi, Yukari Kambe, Akira Tsuchiya
Article Number: 4
Published online on: 23 October 2025

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Article Open Access

Investigating the roles of microRNAs associated with cancer stem cells, drug resistance, metastasis and recurrence in hepatocellular carcinoma: A systematic review, network analysis and experimental verification

Yuanyuan Jiang, Xiaoning Zhu, Qinghua Peng, Paniz Zarghami Dastjerdi, Mengyun Peng, Ding Zheng, Xiaodong Wang, Yoke Kqueen Cheah, Jing Wang
Article Number: 3
Published online on: 23 October 2025

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Case Report Open Access

Advanced dual primary male breast cancer and lung cancer: A case report and literature review

Xiaoxiao Xing, Junyi Li, Yue Wang, Shiyun Zhang, Jun Li, Yun Wang, Dongpo Zhang, Daixiang Liao
Article Number: 2
Published online on: 22 October 2025

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Retraction Open Access

[Retracted] Tumor necrosis factor‑related apoptosis‑inducing ligand inhibits proliferation and induces apoptosis of prostate and bladder cancer cells

Lin Hao, Yan Zhao, Zhi-Gang Li, Hou-Guang He, Qing Liang, Zhi-Guo Zhang, Zhen-Duo Shi, Pei-Ying Zhang, Cong-Hui Han
Article Number: 1
Published online on: 22 October 2025

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Journal Cover
February-2026 Volume 31 Issue 2

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Case Report Open Access

Primary bone marrow diffuse large B‑cell lymphoma with secondary myelofibrosis: A case report

Jing Yang, Sheng-Ke Tu, Hui Peng, Yuan-Yuan Peng, Min Li, Kui Song
Article Number: 70
Published online on: 05 December 2025

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Tanshinone IIA targets RNF123 to inhibit non‑small cell lung cancer cell proliferation, migration and invasion via KAT2B‑mediated H3K18ac modification

Yongjie He, Yingxin Zhang, Jiangsheng Zhang, Kaican Cai
Article Number: 69
Published online on: 04 December 2025

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Expression profiling reveals coordinated dysregulation of autophagy‑associated proteins in marginal zone lymphoma and therapeutic implications

Jingshu Ruan, Xin Zhou, Ai Li, Ningning Shan
Article Number: 68
Published online on: 03 December 2025

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Analysis of the TCRβ repertoire characteristics when combining radiotherapy and immunotherapy in cancer

Xueli Yang, Wujun Wei, Zhihui Feng, Biao Zhang, Yi Liu, Fei Yang, Chong Zhang, Minglin Ou, Songbai Liao, Xianliang Hou
Article Number: 67
Published online on: 03 December 2025

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Identification and validation of critical mitochondrial hub genes for prostate cancer

Sha Liu, Liang Huang, Li Lin, Hong Shan, Yueming Wan
Article Number: 66
Published online on: 03 December 2025

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Roles of minimally invasive techniques in the management of epithelial ovarian cancer (Review)

Ruibing Yang, Jiali Gao, Yunyun Cheng, Caihong Lu, Juan Li
Article Number: 65
Published online on: 03 December 2025

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Case Report Open Access

Pregnancy with vitrified oocytes after fertility sparing surgery in a patient with fallopian tube cancer and a BRCA2 mutation: A case report and literature review

Guglielmo Stabile, Stefania Cicogna, Gabriella Zito, Anna Vido, Andrea Romano, Alessandro Mangogna, Luigi Nappi, Giuseppe Ricci
Article Number: 64
Published online on: 02 December 2025

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[Retracted] Clinical significance and effect of Sam68 expression in gastric cancer

Jinzhang Xiao, Qiuhong Wang, Qichang Yang, Hua Wang, Fulin Qiang, Song He, Jin Cai, Lei Yang, Yingying Wang
Article Number: 63
Published online on: 02 December 2025

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Genome‑wide CRISPR screening identifies CLDN1 as a central node in the anticancer mechanisms of berberine and as a therapeutic target in lung cancer

Xiaogang Wang, Benzhong Mi, Jinfeng Lv, Xin Tang, Jingyu Huang, Fei Liu, Yajing Xing, Xingjian Wen, Yongde Wang, Yadong Zhong
Article Number: 62
Published online on: 01 December 2025

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Construction of a human epidermal growth factor receptor 2‑related gene risk model for predicting breast cancer prognosis

Limin Huang, Chunhong Xu, Yining Song, Furong Sun, Xuemei Sun, Hanyi Yao, Mingchen Liu, Nan Luo
Article Number: 61
Published online on: 01 December 2025

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Development of a machine learning model for preoperative prediction of spread through air spaces in resectable 
non‑small cell lung cancer: A single‑center retrospective study

Chong Yang, Guozheng Ding, Bicheng Zhan, Lanlan Xuan, Feifei Cheng, Yanguo Yang
Article Number: 60
Published online on: 01 December 2025

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Case Report Open Access

Integrated diagnostic evaluation of multiple malignant neoplasms via 99mTc‑MDP three‑phase bone imaging: A case report

Jing-Yi Lian, Jian-Lin Lu, Hui-Yu Zheng, Si-Xia Yuan, Jin-Shan Zhang
Article Number: 59
Published online on: 01 December 2025

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Article

Retrospective analysis of the association between monocyte percentage and outcomes in newly diagnosed diffuse large B‑cell lymphoma

Chaoqiang Zheng, Xiaoqin Xin
Article Number: 58
Published online on: 28 November 2025

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Role of HOXA transcript antisense RNA myeloid‑specific 1 in cancer (Review)

Yipei Jing, Xiaoqi Li, Ye Guo
Article Number: 57
Published online on: 28 November 2025

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Differential gene expression analysis reveals signaling pathways of proliferation, angiogenesis and metastasis is associated with interferon suppression in advanced hypopharyngeal cancer cells

Chia-Wei Kao, Yen-Ping Yeh, Ting-Wen Chen, Min-Ying Lin, Jyh-Der Leu, Yi-Jang Lee
Article Number: 56
Published online on: 27 November 2025

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Unicentric Castleman disease with paraneoplastic pemphigus and follicular dendritic cell sarcoma: A case report

Yukun Li, Fanchen Zeng, Zeyao Wang, Ganjian Zhao, Qi Zhou
Article Number: 55
Published online on: 27 November 2025

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CRISPR/Cas9‑mediated claudin‑2 knockout in HCT116 cells reveals its key role in colorectal cancer progression

Rana A. Alghamdi, Maryam H. Al‑zahrani
Article Number: 54
Published online on: 27 November 2025

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Article Open Access

Comparative evaluation of microRNA detection in plasma, urine and liquid‑based cytology for high‑grade cervical intraepithelial neoplasia

Stéphanie Calfa, Ana Julia Aguiar De Freitas, Welinton Hirai, Júlio César Possati‑Resende, Rhafaela Lima Causin, Ricardo Dos Reis, Rui Manuel Reis, Márcia Maria Chiquitelli Marques
Article Number: 53
Published online on: 26 November 2025

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Case Report Open Access

Small intestinal SMARCA4‑deficient undifferentiated carcinoma with intussusception: A case report

Xiaoshan Cai, Shanshan Liu, Linqian Li, Yuming Zhang, Qin Guo, Ze Chen, Meihua Qu, Yubing Wang, Ben Yang, Xianwen Yue
Article Number: 52
Published online on: 26 November 2025

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SENP5 acts as a downstream target of androgen receptor and contributes to prostate cancer growth

Ximin Chen, Xubo Gong, Jingcheng Zhang, Weiwei Liu
Article Number: 51
Published online on: 26 November 2025

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Retraction Open Access

[Retracted] Scutellarein suppresses Aβ‑induced memory impairment via inhibition of the NF‑κB pathway in vivo and in vitro

Xiao-Wei Huang, Yan Xu, Xin Sui, He Lin, Jia-Ming Xu, Dong Han, Dou-Dan Ye, Guang-Fu Lv, Yue-Xin Liu, Xiao-Bo Qu, Ming-Hua Duan
Article Number: 50
Published online on: 26 November 2025

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Article Open Access

Prognostic analysis and expression patterns of programmed cell death ligand 1 and BRAF V600E in esophageal neuroendocrine carcinoma

Chengcheng Zhang, Li Zheng, Binwen Xu, Guidong Shi, Maoyong Fu
Article Number: 49
Published online on: 25 November 2025

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Article

Evaluating computer‑assisted mandibular reconstruction: Outsourced vs. in‑house approaches

Sho Katsura, Yoshihiro Morita, Ryotaro Kakimoto, Tetsuo Miyamoto, Kana Kashima, Emiko Ogasa, Yoshio Ueno, Ayano Tobe‑Nishimoto, Satoko Kishimoto, Yuka Matsumiya‑Matsumoto, Akinori Takeshita, Kazuhide Matsunaga, Narikazu Uzawa
Article Number: 48
Published online on: 25 November 2025

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Case Report Open Access

Multiple primary central nervous system lymphoma in the ventricular system and interpeduncular cistern: A case report

Qing Ouyang, Bing Sun, Haodong Sun, Jianing Luo, Zhen Xu, Yuan Ma
Article Number: 47
Published online on: 25 November 2025

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Exploration of immunotherapy modalities in stage III unresectable non‑small cell lung cancer (Review)

Jiayun Ma, Jun Jiang
Article Number: 46
Published online on: 25 November 2025

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Case Report

Massive breast fat necrosis with invasive breast cancer: A case report

Anjie Zhang, Linfeng Song, Xiyao Yang, Xu Chen, Binlin Tian, Yongzhe Li, Guoyuan Jiang, Lin Jiang
Article Number: 45
Published online on: 25 November 2025

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