Five-point scoring system based on clinicopathological data: A convenient criterion to determine prognosis of patients with colorectal carcinoma

Nozoe,Tadahiro; Kohno,Mayuko; Iguchi,Tomohiro; Maeda ,Takashi; Ezaki,Takahiro

doi:10.3892/ol.2013.1115

March 2013 Volume 5 Issue 3

Full Size Image

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

An International Open Access Journal Devoted to General Medicine.

March 2013 Volume 5 Issue 3

Full Size Image

Article

Five-point scoring system based on clinicopathological data: A convenient criterion to determine prognosis of patients with colorectal carcinoma

Authors:
- Tadahiro Nozoe
- Mayuko Kohno
- Tomohiro Iguchi
- Takashi Maeda
- Takahiro Ezaki
View Affiliations / Copyright

Affiliations: Department of Surgery, Fukuoka Higashi Medical Center, Koga 811-3195, Japan
Pages: 978-982
|
Published online on: January 8, 2013

https://doi.org/10.3892/ol.2013.1115
Expand metrics +

Abstract

The aim of this study was to elucidate the significance of a novel staging criterion, a five-point scoring system (FPSS), determined by five histopathological factors of colorectal carcinoma. These factors included depth of invasion, lymph node metastasis, lymphatic invasion, venous invasion and histopathological tumor type. In total, 357 patients with colorectal carcinoma who had had been treated by surgical resection were investigated. One point was assigned to each of the five aforementioned tumor-related pathological factors. The FPSS score was determined by an aggregate of the points. A significant difference was observed between the survival of patients with FPSS scores of 0 and 1, and 2 and 3 (P=0.0002); and FPSS scores of 2 and 3, and 4 and 5 (P<0.0001). We demonstrate that the FPSS is a convenient criterion for stratifying the prognosis of patients with colorectal carcinoma.

View Figures

View References

1	Nozoe T, Mori E, Iguchi T, Kohno M, Maeda T, Ezaki T and Sueishi K: Pathological prognostic score; A rational criteria to stratify survival in colorectal carcinoma. J Surg Oncol. 106:243–247. 2012. View Article : Google Scholar : PubMed/NCBI
2	Nozoe T, Mori E, Takahashi I and Ezaki T: Preoperative elevation of serum C-reactive protein as an independent prognostic indicator of colorectal carcinoma. Surg Today. 38:597–602. 2008. View Article : Google Scholar : PubMed/NCBI
3	Japanese Society for Cancer of the Colon and Rectum: Japanese classification of colorectal carcinoma. 7th English edition. Kanehara Company; Tokyo: pp. 6–33. 2009
4	Sobin L, Gospodarowicz M and Wittekind C: International Union Against Cancer TNM classification of malignant tumours. 7th edition. Wiley-Blackwell; New York: pp. 100–105. 2009
5	Nozoe T, Iguchi T, Egashira A, Adachi E, Matsukuma A and Ezaki T: Pathological prognostic score as a simple criterion to predict outcome in gastric carcinoma. J Surg Oncol. 102:73–76. 2010. View Article : Google Scholar : PubMed/NCBI
6	Chung CK, Zaino RJ and Stryker JA: Colorectal carcinoma: evaluation of histologic grade and factors influencing prognosis. J Surg Oncol. 21:143–148. 1982. View Article : Google Scholar : PubMed/NCBI
7	Nozoe T, Anai H, Nasu S and Sugimachi K: Clinicopathological characteristics of mucinous carcinoma of the colon and rectum. J Surg Oncol. 75:103–107. 2000. View Article : Google Scholar : PubMed/NCBI
8	Nozoe T, Inutsuka S, Honda M, Ezaki T and Korenaga D: Clinicopathologic significance of cyclin A expression in colorectal carcinoma. J Exp Clin Cancer Res. 23:127–133. 2004.PubMed/NCBI
9	Takeuchi K, Kuwano H, Tsuzuki Y, Ando T, Sekihara M, Hara T and Asao T: Clinicopathological characteristics of poorly differentiated adenocarcinoma of the colon and rectum. Hepatogastroenterology. 51:1698–1702. 2004.PubMed/NCBI
10	Kazama Y, Watanabe T, Kanazawa T, Tanaka J, Tanaka T and Nagawa H: Microsatellite instability in poorly differentiated adenocarcinomas of the colon and rectum: relationship to clinicopathological features. J Clin Pathol. 60:701–704. 2007. View Article : Google Scholar
11	Ogawa M, Watanabe M, Eto K, et al: Poorly differentiated adenocarcinoma of the colon and rectum: clinical characteristics. Hepatogastroenterology. 55:907–911. 2008.PubMed/NCBI
12	Ueno H, Mochizuki H, Hashiguchi Y, et al: Histological grading of colorectal cancer: a simple and objective method. Ann Surg. 247:811–818. 2008. View Article : Google Scholar : PubMed/NCBI
13	Ishihara S, Watanabe T, Akahane T, et al: Tumor location is a prognostic factor in poorly differentiated adenocarcinoma, mucinous adenocarcinoma, and signet-ring cell carcinoma of the colon. Int J Colorectal Dis. 27:371–379. 2012. View Article : Google Scholar
14	Nozoe T and Sugimachi K: Simple staging criteria for esophageal carcinoma: classification with a strict prognostic stratification. Am J Clin Oncol. 26:307–311. 2003. View Article : Google Scholar : PubMed/NCBI

Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Five-point scoring system based on clinicopathological data: A convenient criterion to determine prognosis of patients with colorectal carcinoma

This article is mentioned in:

Abstract

Figure 1

Figure 2

Related Articles