Treatment of cervical vertebral (C1) metastasis of lung cancer with radiotherapy: A case report

Ni,Xuefeng; Wu,Ping; Wu,Changping; Wu,Jianfeng; Ji,Mei; Gu,Xiaofang; Tian,Bo

doi:10.3892/ol.2013.1183

Treatment of cervical vertebral (C1) metastasis of lung cancer with radiotherapy: A case report

Authors:
- Xuefeng Ni
- Ping Wu
- Changping Wu
- Jianfeng Wu
- Mei Ji
- Xiaofang Gu
- Bo Tian
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Affiliations: Department of Oncology, The Third Affiliated Hospital, Soochow University, Changzhou, Jiangsu 213003, P.R. China, Department of Pharmacology, The Third Affiliated Hospital, Soochow University, Changzhou, Jiangsu 213003, P.R. China, Department of Radiation Oncology, Jiangsu Cancer Hospital and Research Institute, Nanjing, Jiangsu 210009, P.R. China, Department of Radiology, The Third Affiliated Hospital, Soochow University, Changzhou, Jiangsu 213003, P.R. China, Department of Pathology, The Third Affiliated Hospital, Soochow University, Changzhou, Jiangsu 213003, P.R. China
Published online on: February 6, 2013 https://doi.org/10.3892/ol.2013.1183
Pages: 1129-1132

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Abstract

The present study discusses a patient with C1 vertebral metastasis from adenocarcinoma of the left lung. The patient was a 31‑year‑old female suffering from neck pain who was referred by her physician. Magnetic resonance imaging revealed osteolytic destruction of the C1 vertebra. Chest and computed tomographic scans revealed lung carcinoma changes involving the left lung. A biopsy confirmed adenocarcinoma of the left lung. Abnormal activity was present in the cervical spine (C1) region in a radionuclide bone scan. The patient was then referred to an oncologist. The spine was stabilized with a rigid collar and a course of radiation therapy and pain medication was initiated immediately. At the 9‑month follow‑up examination, there was no evidence of progression on the MRI scans and the main neck symptoms had disappeared. At present, the overall survival (OS) time is 11 months. Patients complaining of new onset back or neck pain should be assumed to have vertebral metastasis until proven otherwise. Trivial trauma should be taken seriously in these cases and investigated with appropriate clinical, laboratory and imaging examinations.

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