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Oncology Letters
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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
April 2013 Volume 5 Issue 4

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Review

Aflatoxin B1-induced hepatocellular carcinoma in developing countries: Geographical distribution, mechanism of action and prevention (Review)

Abdu Selim Hamid, Isaias Goitom Tesfamariam, Yucheng Zhang, Zhen Gui Zhang
Pages: 1087-1092
Published online on: 31 January 2013

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Review

Expression of the PXR gene in various types of cancer and drug resistance (Review)

Enqi Qiao, Minghua Ji, Jianzhong Wu, Rong Ma, Xiaohua Zhang, Yuejun He, Quanbin Zha, Xue Song, Li‑Wei Zhu, Jinhai Tang
Pages: 1093-1100
Published online on: 22 January 2013

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Review

Role of the nervous system in cancer metastasis (Review)

Sha Li, Yanlai Sun, Dongwei Gao
Pages: 1101-1111
Published online on: 31 January 2013

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Article

Arachidonic acid supplementation does not affect N-methyl-N-nitrosourea-induced renal preneoplastic lesions in young Lewis rats

Katsuhiko Yoshizawa, Yuko Emoto, Yuichi Kinoshita, Ayako Kimura, Norihisa Uehara, Takashi Yuri, Nobuaki Shikata, Tomohito Hamazaki, Airo Tsubura
Pages: 1112-1116
Published online on: 30 January 2013

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Article

Vascular endothelial growth factor expression and T-regulatory cells in premenopausal breast cancer

Francesco Recchia, Giampiero Candeloro, Stefano Necozione, Giovambattista Desideri, Alisia Cesta, Laura Recchia, Silvio Rea
Pages: 1117-1122
Published online on: 18 January 2013

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Article

Nail alterations as a surrogate marker for the efficacy of low-dose metronomic chemotherapy

Kayoko Kibata, Takeshi Tamaki, Noriko Inagaki, Makoto Ogata, Toshiki Shimizu, Shosaku Nomura
Pages: 1123-1128
Published online on: 05 February 2013

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Case Report

Treatment of cervical vertebral (C1) metastasis of lung cancer with radiotherapy: A case report

Xuefeng Ni, Ping Wu, Changping Wu, Jianfeng Wu, Mei Ji, Xiaofang Gu, Bo Tian
Pages: 1129-1132
Published online on: 06 February 2013

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Article

Expression of osteoprotegerin and osteoprotegerin ligand in giant cell tumor of bone and its clinical significance

Xiuchun Yu, Weiqing Kong, Kai Zheng
Pages: 1133-1139
Published online on: 19 February 2013

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Article

A study of docetaxel weekly or every three weeks in combination with carboplatin as first line chemotherapy in epithelial ovarian cancer: Hematological and non-hematological toxicity profiles

Bengt Sorbe, Marianne Graflund, Lisa Nygren, György Horvath
Pages: 1140-1148
Published online on: 22 January 2013

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Article

Repression of Dicer is associated with invasive phenotype and chemoresistance in ovarian cancer

Yan Kuang, Jing Cai, Donglin Li, Qin Han, Jin Cao, Zehua Wang
Pages: 1149-1154
Published online on: 28 January 2013

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Article

The clinical and prognostic implications of pluripotent stem cell gene expression in hepatocellular carcinoma

Xin Yin, Yi-Wei Li, Jian-Jun Jin, Yin Zhou, Zheng-Gang Ren, Shuang-Jian Qiu, Bo-Heng Zhang
Pages: 1155-1162
Published online on: 23 January 2013

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Case Report

Cutaneous leiomyoma in a child: A case report

Nursel Dilek, Derya Yüksel, İbrahim Şehitoğlu, Yunus Saral
Pages: 1163-1164
Published online on: 15 February 2013

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Article

Polymorphisms in thymidylate synthase and reduced folate carrier (SLC19A1) genes predict survival outcome in advanced non‑small cell lung cancer patients treated with pemetrexed‑based chemotherapy

Wen‑Juan Li, Hua Jiang, Xin‑Jian Fang, Hong‑Ling Ye, Ming‑Huan Liu, Yan‑Wen Liu, Qian Chen, Li Zhang, Jin‑Yu Zhang, Chun‑Luan Yuan, Qiu‑Yun Zhang
Pages: 1165-1170
Published online on: 04 February 2013

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Article

Huaier aqueous extract inhibits colorectal cancer stem cell growth partially via downregulation of the Wnt/β‑catenin pathway

Tao Zhang, Ke Wang, Junshu Zhang, Xiaolei Wang, Zhigang Chen, Chao Ni, Fuming Qiu, Jian Huang
Pages: 1171-1176
Published online on: 21 January 2013

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Article

The role of pro-inflammatory cytokines and immune cells in colorectal carcinoma progression

Huanran Liu, Zhen Zhang, Takafumi Tabuchi, Shouyu Wang, Jiangning Wang
Pages: 1177-1182
Published online on: 05 February 2013

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Article

Small antibody fusion proteins with complementarity‑determining regions and lidamycin for tumor targeting therapy

Gen-Shen Zhong, Min-Na Wu, Xiao-Fang Guo, Zhi‑Shan Xu, Sheng-Hua Zhang, Yong-Su Zhen
Pages: 1183-1188
Published online on: 18 January 2013

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Article

CD146 is a potential marker for the diagnosis of malignancy in cervical and endometrial cancer

Haofeng Zhang, Jun Zhang, Zhaoqing Wang, Di Lu, Jing Feng, Dongling Yang, Xiuqin Chen, Xiyun Yan
Pages: 1189-1194
Published online on: 22 January 2013

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Article

The CD79α (HM47/A9) antibody is effective in distinguishing between primary hepatocellular carcinoma and primary intrahepatic cholangiocarcinoma

Hao Li, Congyang Li
Pages: 1195-1198
Published online on: 30 January 2013

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Article

Expression of DNA-PKcs and BRCA1 as prognostic indicators in nasopharyngeal carcinoma following intensity-modulated radiation therapy

Jiao Yang, Ximing Xu, Yanrong Hao, Jiaxin Chen, Heming Lu, Jian Qin, Luxing Peng, Biao Chen
Pages: 1199-1204
Published online on: 18 February 2013

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Article

Effects of T‑cadherin expression on B16F10 melanoma cells

Xin‑Suo Duan, Jie Lu, Zhi‑Hua Ge, En‑Hong Xing, Hai‑Tao Lu, Li‑Xin Sun
Pages: 1205-1210
Published online on: 30 January 2013

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Article

Abnormal methylation of seven genes and their associations with clinical characteristics in early stage non-small cell lung cancer

Yangxing Zhao, Huafu Zhou, Kelong Ma, Jinfeng Sun, Xu Feng, Junfeng Geng, Jun Gu, Wei Wang, Hongyu Zhang, Yinghua He, Shicheng Guo, Xiaoyu Zhou, Jian Yu, Qiang Lin
Pages: 1211-1218
Published online on: 29 January 2013

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Article

HPV genotypes in paraffin sections of non-cervical squamous cell carcinoma in Qingdao of China

Zhi Di Gao, Qi Pan, Hong Lv, Yang Sun, Xiaoye Ma, Zuorong Qin, Yu Ping Sun
Pages: 1219-1222
Published online on: 06 February 2013

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Article

miR-26a inhibits invasion and metastasis of nasopharyngeal cancer by targeting EZH2

Li Yu, Juan Lu, Bao Zhang, Xiong Liu, Lu Wang, Si-Yang Li, Xiao-Hong Peng, Xia Xu, Wen-Dong Tian, Xiang-Ping Li
Pages: 1223-1228
Published online on: 04 February 2013

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Case Report

Diagnosis and treatment of a patient with isolated spinal granulocytic sarcoma: A case report

Ruo‑Zhi Xiao, Zi‑Jie Long, Mu‑Jun Xiong, Wen‑Wen Wang, Dong‑Jun Lin
Pages: 1229-1232
Published online on: 19 February 2013

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Case Report

One-stage laparoscopic resection for a large gastric gastrointestinal stromal tumor and synchronous liver metastases following preoperative imatinib therapy: A case report

Feng Cao, Jia Li, Ang Li, Yu Fang, Fei Li
Pages: 1233-1236
Published online on: 18 February 2013

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Case Report

Gemcitabine and cisplatin-induced tumor lysis syndrome in a patient with gallbladder carcinoma: A case report

Deiter J. Duff, Shadi Haddadin, Carl Freter, Chris Papageorgiou
Pages: 1237-1239
Published online on: 12 February 2013

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Case Report

Post-orchidectomy retroperitoneal seminoma: A case report

Piero Caglià, Angelo Tracia, Rosita A. Condorelli, Aldo E. Calogero, Enzo Vicari, Massimiliano Veroux, Corrado Amodeo, Ylenia Duca, Luciano Tracia, Antonino F. Arcoria, Chiara Nicoletti, Laura MongioÌ, Sandro La Vignera
Pages: 1240-1242
Published online on: 23 January 2013

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Article

Overexpression of hnRNPC2 induces multinucleation by repression of Aurora B in hepatocellular carcinoma cells

Da-Quan Sun, Ying Wang, Ding-Gan Liu
Pages: 1243-1249
Published online on: 31 January 2013

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Case Report

Acute liver failure associated with diffuse liver infiltration by metastatic breast carcinoma: A case report

Suchanan Hanamornroongruang, Napakorn Sangchay
Pages: 1250-1252
Published online on: 30 January 2013

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Article

Malignant transformation of residual endometriosis following hysterectomy and bilateral salpingo‑oophorectomy in a female patient from a family with hereditary non‑polyposis colorectal cancer

Yuxuan Chen, Yan Zhai, Xiaoying Jiang, Zhenyu Zhang
Pages: 1253-1257
Published online on: 06 February 2013

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Case Report

Pelvic and muscular metastasis of a renal cell carcinoma: A case report

Carolina D'Elia, Tommaso Cai, Lorenzo Luciani, Mariella Bonzanini, Gianni Malossini
Pages: 1258-1260
Published online on: 01 February 2013

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Article

Effect of autophagy inhibition on chemotherapy‑induced apoptosis in A549 lung cancer cells

Feifei Liu, Donglei Liu, Yang Yang, Song Zhao
Pages: 1261-1265
Published online on: 25 January 2013

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Article

Younger patients with chronic lymphocytic leukemia benefit from rituximab treatment: A single center study in China

Zhenshu Xu, Jinyan Zhang, Shunquan Wu, Zhihong Zheng, Zhizhe Chen, Rong Zhan
Pages: 1266-1272
Published online on: 05 February 2013

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Article

Epigenetic effects of the natural flavonolignan silibinin on colon adenocarcinoma cells and their derived metastatic cells

Henriette Kauntz, Souad Bousserouel, Francine Gossé, Francis Raul
Pages: 1273-1277
Published online on: 12 February 2013

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Article

Expression of the IAP protein family acts cooperatively to predict prognosis in human bladder cancer patients

Xiaochi Chen, Tiezheng Wang, Deyong Yang, Jianbo Wang, Xiancheng Li, Zhongzhou He, Feng Chen, Xiangyu Che, Xishuang Song
Pages: 1278-1284
Published online on: 23 January 2013

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Article

Overexpression of HIF-1α indicates a poor prognosis in tongue carcinoma and may be associated with tumour metastasis

Yang Zheng, Yanhong Ni, Xiaofeng Huang, Zhiyong Wang, Wei Han
Pages: 1285-1289
Published online on: 07 February 2013

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Article

RNA interference‑mediated USP22 gene silencing promotes human brain glioma apoptosis and induces cell cycle arrest Retraction in /10.3892/ol.2023.13756

Zhao Hui Li, Yin Yu, Chao Du, Hong Fu, Jian Wang, Yu Tian
Pages: 1290-1294
Published online on: 12 February 2013

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Article

Expression of E-cadherin and KRAS mutation may serve as biomarkers of cetuximab-based therapy in metastatic colorectal cancer

Kentaro Nakamoto, Hisashi Nagahara, Kiyoshi Maeda, Eiji Noda, Toru Inoue, Masakazu Yashiro, Yukio Nishiguchi, Masaichi Ohira, Kosei Hirakawa
Pages: 1295-1300
Published online on: 08 February 2013

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Case Report

Imaging findings of ossifying fibromyxoid tumor with histopathological correlation: A case report

Soshi Ideta, Jun Nishio, Mikiko Aoki, Tetsuro Ishimatsu, Kazuki Nabeshima, Hiroshi Iwasaki, Masatoshi Naito
Pages: 1301-1304
Published online on: 31 January 2013

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Article

Endometrial pathology in breast cancer patients: Effect of different treatments on ultrasonographic, hysteroscopic and histological findings

Maria Le Donne, Angela Alibrandi, Leonarda Ciancimino, Andrea Azzerboni, Benito Chiofalo, Onofrio Triolo
Pages: 1305-1310
Published online on: 28 January 2013

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Case Report

Composite tumor of metanephric adenoma and Wilms' tumor of the kidney: A case report and review of the literature

Pengcheng Zhu, Fei Yan, Zixuan Yang, Li Meng, Qilin Ao
Pages: 1311-1314
Published online on: 22 January 2013

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Article

Genotyping of stathmin and its association with clinical factors and survival in patients with ovarian cancer

Lisha Ying, Dan Su, Jianqing Zhu, Shenglin Ma, Dionyssios Katsaros, Herbert Yu
Pages: 1315-1320
Published online on: 18 January 2013

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Case Report

Successful treatment with low-dose decitabine in acute myelogenous leukemia in elderly patients over 80 years old: Five case reports

Jie Lin, Hongli Zhu, Suxia Li, Hui Fan, Xuechun Lu, Cheng Chang, Bo Guo, Bing Zhai
Pages: 1321-1324
Published online on: 18 January 2013

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Article

Androgen receptor decreases the cytotoxic effects of chemotherapeutic drugs in upper urinary tract urothelial carcinoma cells

Teng-Fu Hsieh, Chi-Cheng Chen, Ai-Lin Yu, Wen-Lung Ma, Caixia Zhang, Chih-Rong Shyr, Chawnshang Chang
Pages: 1325-1330
Published online on: 18 January 2013

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Article

Safety and efficacy of panitumumab therapy after metastatic colorectal cancer progression with cetuximab: Experience at a single Japanese institution

Hiromichi Sonoda, Eiji Mekata, Tomoharu Shimizu, Yoshihiro Endo, Tohru Tani
Pages: 1331-1334
Published online on: 01 February 2013

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Article

The sternocleidomastoid muscle flap for the prevention of Frey syndrome and cosmetic deformity following parotidectomy: A systematic review and meta-analysis

Dong Yan Liu, Xiao Jiao Tian, Cheng Li, Shao Shan Sun, Ying Hui Xiong, Xian-Tao Zeng
Pages: 1335-1342
Published online on: 05 February 2013

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Article

Different medical expenses incurred by appendiceal cystadenoma in China: Report of three cases

Guo-Sheng Wang, Liu Yang, Hai-Fen Ma, Yuan Gao
Pages: 1343-1346
Published online on: 04 February 2013

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Article

Synuclein‑γ suppression mediated by RNA interference inhibits the clonogenicity and invasiveness of MCF‑7 cells

Bo Liang, Xin‑Jun Wang, Pei‑Hong Shen, Xue‑Yuan Li, Hong‑Wei Cheng, Qiao Shan, Kui‑Yuan Guo, Yu‑Wen Cao, Qing‑Xia Fan, Rui‑Feng Zheng, Bei Li, Wei Zhang, Yan‑Wei Li, Kai Yang
Pages: 1347-1352
Published online on: 14 February 2013

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Article

HMGA2 induces epithelial-to-mesenchymal transition in human hepatocellular carcinoma cells

Yizhou Luo, Wenfeng Li, Hui Liao
Pages: 1353-1356
Published online on: 15 February 2013

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Article

Pseudomonas aeruginosa‑mannose‑sensitive hemagglutinin inhibits proliferation and induces apoptosis in a caspase‑dependent manner in human bladder cancer cell lines

Yi‑Ping Zhu, Xiao‑Jie Bian, Ding‑Wei Ye, Xu‑Dong Yao, Shi‑Lin Zhang, Bo Dai, Yi‑Jun Shen
Pages: 1357-1362
Published online on: 19 February 2013

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Article

Comparison of the expression of 5 heat shock proteins in benign and malignant salivary gland tumor tissues

Guilan Wang, Xiaolin Gu, Li Chen, Yinmei Wang, Bin Cao, Qun E
Pages: 1363-1369
Published online on: 30 January 2013

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Article

Density‑dependent lineage instability of MDA‑MB‑435 breast cancer cells

Andreas G. Nerlich, Beatrice E. Bachmeier
Pages: 1370-1374
Published online on: 28 January 2013

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Article

Suppression of NF-κB activity by mutant IκBα: A molecular target for radiosensitization of adenoid cystic carcinoma

Zhe Liu, Shengyun Huang, Shizhou Zhang, Jiawen Si, Qiang Wang, Qiangxiu Wang, Wenli Mu, Junqing Han, Dongsheng Zhang
Pages: 1375-1381
Published online on: 24 January 2013

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Case Report

Temsirolimus in overtreated metastatic renal cancer with subsequent use of sunitinib: A case report

José Miguel Jurado, Irene Zarcos, Mayte Delgado, Isabel Blancas, Marta Legerén, José Luis García-Puche
Pages: 1382-1384
Published online on: 07 February 2013

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Article

Risk assessment of mouse gastric tissue cancer induced by dichlorvos and dimethoate

Qing-Lu Wang, Yu-Jun Zhang, Cai-Xia Zhou, Jie Zhang, Ye Dou, Qiao-Qiao Li
Pages: 1385-1389
Published online on: 28 January 2013

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Article

Notch2 inhibits proliferation of chronic myeloid leukemia cells

Zesong Yang, Chunxiu Yang, Shunjun Zhang, Ying Li, Jianbin Chen
Pages: 1390-1394
Published online on: 29 January 2013

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Article

Effects of oleic acid on cell proliferation through an integrin-linked kinase signaling pathway in 786-O renal cell carcinoma cells

Zhenhua Liu, Yunbei Xiao, Yeqing Yuan, Xiaowei Zhang, Caipeng Qin, Jing Xie, Yichang Hao, Tao Xu, Xiaofeng Wang
Pages: 1395-1399
Published online on: 29 January 2013

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Article

Combination of four gene markers to detect circulating tumor cells in the peripheral blood of patients with advanced lung adenocarcinoma using real-time PCR

Yan Yu, Gang Xu, Jingyan Cao, Shi Jin, Yingchun Man, Lihua Shang
Pages: 1400-1406
Published online on: 05 February 2013

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Article

Cytotoxic and apoptosis‑inducing properties of a C21‑steroidal glycoside isolated from the roots of Cynanchum auriculatum

Liang‑Fei Ye, Yi‑Qi Wang, Bo Yang, Ru‑Song Zhang
Pages: 1407-1411
Published online on: 07 February 2013

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Article

Hemithyroidectomy increases the risk of disease recurrence in patients with ipsilateral multifocal papillary thyroid carcinoma

Xiaolong Li, Cui Zhao, Dandan Hu, Yang Yu, Jin Gao, Wenchuan Zhao, Ming Gao
Pages: 1412-1416
Published online on: 19 February 2013

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Article

Cyclopamine is a novel Hedgehog signaling inhibitor with significant anti‑proliferative, anti‑invasive and anti‑estrogenic potency in human breast cancer cells

Jun Che, Fu‑Zheng Zhang, Chao‑Qian Zhao, Xu‑Dong Hu, Sai‑Jun Fan
Pages: 1417-1421
Published online on: 18 February 2013

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Article

Overexpression of claudin-4 may be involved in endometrial tumorigenesis

Xiao-Yu Pan, Xue Li, Yan-Ci Che, Hong-Yan Li, Xin Li, Yun Zhang, Xin Yang
Pages: 1422-1426
Published online on: 18 February 2013

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Case Report

Cytokine‑induced killer cell therapy for advanced pancreatic adenocarcinoma: A case report and review of the literature

Wei Li, Lin Ping Xu, Ling Di Zhao, Li Wang, Yong Zhang, Quan Li Gao, Ling Mai
Pages: 1427-1429
Published online on: 19 February 2013

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Case Report

The management of retroperitoneal giant schwannomas in AIDS patients: A case report

Zhang Ke, Mu Yi, Jiang Li, Huang‑Rong Hai, Lu Yan, He Rong, Ding‑Zhen Hao, Guo‑Li Min, Li‑Qin Tao, Li‑Bao Liang, Jia Zhe
Pages: 1430-1432
Published online on: 13 February 2013

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Correction

[Corrigendum] Analysis of complete response by MRI following neoadjuvant chemotherapy predicts pathological tumor responses differently for molecular subtypes of breast cancer

Yuji Hayashi, Hiroyuki Takei, Satoshi Nozu, Yoshihiro Tochigi, Akihiro Ichikawa, Naoki Kobayashi, Masafumi Kurosumi, Kenichi Inoue, Takashi Yoshida, Shigenori E. Nagai, Hanako Oba, Toshio Tabei, Jun Horiguchi, Izumi Takeyoshi
Pages: 1433-1433
Published online on: 18 January 2013

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January-2026 Volume 31 Issue 1

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Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

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Predictive analysis of BRAF V600E mutation and central lymph node metastasis in papillary thyroid carcinoma

Junhui Peng, Zhihui Wu, Yujun Huang, Runhua Pan, Zhongdai Fu, Jianzhang Wang
Article Number: 44
Published online on: 24 November 2025

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Adverse events induced by the subcutaneous HER2-targeted antibody‑drug conjugate JSKN033 in a male patient with breast cancer: A case report

Rui Yang, Jian Zhang, Yang Wang
Article Number: 43
Published online on: 24 November 2025

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Prediction of solitary ≤3‑cm small adrenal metastasis based on 18F‑FDG PET/CT using a support vector machine model in lung cancer

Lin Zhao, Haifeng Cai, Jingwu Li, Wenzhe Zhao, Yongliang Liu, Lixiu Cao
Article Number: 42
Published online on: 24 November 2025

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Transferrin receptor serves a role in promoting PANoptosis in thyroid cancer

Shungao Ma, Zhiqiang Ma, Jingwei Shen, Hong Liu, Hua Yang, Yuqin Hu, Simeng Ying
Article Number: 41
Published online on: 24 November 2025

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Oxidative stress as a nexus: Integrating mitophagy and ferroptosis in endometrial carcinogenesis (Review)

Qixia Yu, Liangxin Ren, Feng Ren, Fengling Li
Article Number: 40
Published online on: 20 November 2025

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Astragalin: A promising herbal compound with broad anticancer potential (Review)

Yu-Qian Fu, Chan Li, Dan-Ni Ding, Fang-Yuan Liu, Yu-Fei Zhu, Feng-Juan Han
Article Number: 39
Published online on: 20 November 2025

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Analysis of prognostic factors influencing brain metastasis in EGFR‑mutant lung adenocarcinoma and comparison of prognostic assessment models

Junjun Miao, Jianwei Hu, Yongxia Zhang, Lei Gao, Xiangkun Yuan
Article Number: 38
Published online on: 18 November 2025

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Fumarate hydratase-deficient renal cell carcinoma arising in acquired cystic kidney disease in a hemodialysis patient: Diagnostic clues from percutaneous renal mass core needle biopsy: A case report

Yuki Oba, Hisashi Kamido, Kei Kono, Katsuyuki Miki, Shinji Ito, Akinari Sekine, Shigekazu Kurihara, Masayuki Yamanouchi, Tatsuya Suwabe, Yutaka Takazawa, Kenichi Ohashi, Yoji Nagashima, Yuki Nakamura, Yoshifumi Ubara, Naoki Sawa
Article Number: 37
Published online on: 18 November 2025

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TIMP1 expression in colorectal cancer: Linking prognosis, tumor immunity and molecular pathways

Jiming Gu, Dongming Zhu, Fan Chen, Tongguo Shi, Suhua Xia
Article Number: 36
Published online on: 18 November 2025

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[Retracted] Exosomes from LNCaP cells promote osteoblast activity through miR‑375 transfer

Su-Liang Li, Na An, Bing Liu, Sheng-Yu Wang, Jian-Jun Wang, Yun Ye
Article Number: 35
Published online on: 17 November 2025

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TAS‑102 plus bevacizumab as salvage treatment in colorectal cancer: A retrospective study

Keita Matsumoto, Ryoma Yokoi, Chika Mizutani, Ryuichi Asai, Jesse Yu Tajima, Masahide Endo, Yuji Hatanaka, Takeshi Horaguchi, Masahiro Fukada, Itaru Yasufuku, Yuta Sato, Yoshihiro Tanaka, Katsutoshi Murase, Nobuhisa Matsuhashi
Article Number: 34
Published online on: 14 November 2025

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Research progress on neutrophil extracellular traps and hepatitis‑to‑hepatocellular carcinoma transformation (Review)

Yiwei Wang, Chengyan Zhang, Haonan Wang, Yali Zhou, Yuanbo Yu, Hui Liu, Chuansha Gu
Article Number: 33
Published online on: 14 November 2025

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Remarkable response to Osimertinib plus Gumarontinib for EGFR mutation and concomitant MET exon 14 skipping in a patient with lung adenocarcinoma: A case report

Xuquan Jing, Li Li, Shuangqing Lu, Xiaoyang Zhai, Hui Zhu
Article Number: 32
Published online on: 12 November 2025

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Machine learning‑based signature for prognosis and drug sensitivity in hepatocellular carcinoma using glycolysis‑related gene

Yufan Zhou, Wei Liu, Zhixue Fang, Ke Zhou, Xing Huang, Shanzheng Lu, Weilin Zhang, Qiaocheng Wen, Xu Chen, Zhigang Xiao
Article Number: 31
Published online on: 12 November 2025

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Dual immune checkpoint inhibitor cardonilumab induces immune myocarditis in a patient with cancer‑related myocardial metastasis: A case report

Tianxing Liu, Qiang Li, Renya Zeng, Baidong Zhang, Zhichao Kang, Pengfei Zhang, Zhe Yang
Article Number: 30
Published online on: 12 November 2025

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Retrospective analysis of clinical characteristics, treatment outcomes and prognosis of patients with natural killer/T‑cell lymphoma

Pengye Li, Geraldine Esther Awakossa, Lu Zhou, Qiuhui Li, Xinxiu Liu, Fang Zhu, Tao Liu, Liling Zhang
Article Number: 29
Published online on: 11 November 2025

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From mechanism to targeted therapy: Advances in histone lactylation‑driven cancer progression (Review)

Zhe Jia, Shan Lu, Zhenchuan Wang, Pengfei Ge
Article Number: 28
Published online on: 11 November 2025

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[Retracted] Upregulation of cervical carcinoma expressed PCNA regulatory long non‑coding RNA promotes esophageal squamous cell carcinoma progression

Xiaojun Wang, Liangfen Zhou, Huiyun Zhang, Hui Ou, Wenxing Long, Xiaobao Liu
Article Number: 27
Published online on: 10 November 2025

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Biology of PEST‑containing nuclear proteins as potential targets in ovarian cancer (Review)

Hao Liu, Zhi-Liang Jiang, Yi Liu, Yong-Hao Zhu, Muhammad Usman Akbar, Saadullah Khattak, Zhendong Lu, Muhammad Babar Khawar, Yue Zhang, Umair Ali Khan Saddozai, Xin-Ying Ji
Article Number: 26
Published online on: 07 November 2025

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Survival outcomes and prognostic factors in temporal bone malignancies: A retrospective cohort of 20 patients

Liming Gao, Wenyang Zhang, Ting Ye, Rui Guo, Yin Xia
Article Number: 25
Published online on: 06 November 2025

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Real‑world performance of the machine learning‑based prediction of chemotherapy‑associated adverse effects in lung cancer

Sha Huang, Zhengwei Huang, Zhoujian Sun, Tianao Xie, Xingyu Zhu, Sheng Lu, Zhengxing Huang, Jian Hu, Zhengfu He
Article Number: 24
Published online on: 06 November 2025

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Long non‑coding RNA RP11‑196G11.6 inhibits neuroblastoma progression by regulating the miR‑376a‑3p/RYBP signaling axis

Jie Zhang, Kai Huang, Jianwu Zhou, Wenge Liao, Fei Li, Zhenzhen Zhao, Shan Wang
Article Number: 23
Published online on: 06 November 2025

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Cervical cancer immune microenvironment: Mechanisms of HPV‑mediated immune evasion and advances in immunotherapy (Review)

Xiaojing Zhou, Ren An, Xiangjuan Li
Article Number: 22
Published online on: 05 November 2025

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Mesenchymal stem cell‑derived exosomes: Regulators of progression and suppression in pancreatic cancer (Review)

Haoyan Zhuang, Xuewen Shi
Article Number: 21
Published online on: 04 November 2025

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Advancements in research regarding the influence of the tumor microenvironment on the proliferation and metastasis of osteosarcoma (Review)

Tao Shi, Jianping Kang, Qiyang Wang, Jiamei Song, Xiaofeng He
Article Number: 20
Published online on: 04 November 2025

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Enhanced expression of CXCL1 in renal cell carcinoma facilitates tumor cell malignancy via PI3K/AKT‑dependent mechanisms

Shiliang Gui, Hongrui Zhang, Huiting Xiao, Chen Liu, Yuhang Wang, Baotian Wang, Hongbin Qiu
Article Number: 19
Published online on: 03 November 2025

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Case Report Open Access

Photodynamic therapy with local‑targeted perfusion for recurrent tracheal adenoid cystic carcinoma achieving 12‑year survival: A case report

Luoqi Yang, Lu Wang, Hongwu Wang, Heng Zou
Article Number: 18
Published online on: 03 November 2025

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[Retracted] Tunicamycin inhibits progression of glioma cells through downregulation of the MEG‑3‑regulated wnt/β‑catenin signaling pathway

Xin Li, Lei Xue, Qin Peng
Article Number: 17
Published online on: 03 November 2025

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Non‑targeted metabolomics reveals diagnostic biomarker in the plasma of patients with lung cancer

Yan Liu, Yangmin Li, Haijun Hou, Yanyan Dong, Haitong Tian, Yanan Zhao, Ke Li, Jiayuan Zhou, Fujie Song, Yan Li
Article Number: 16
Published online on: 31 October 2025

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Primary pulmonary angiosarcoma: A case study with genetic insights and potential therapeutic targets

Yanling Zhu, Chunfang Guo
Article Number: 15
Published online on: 31 October 2025

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Progress in the treatment of esophageal neuroendocrine carcinoma (Review)

Jie Shi, Bin He, Heng Di Zhang, Chao Yang Jiang, Ling Zhang
Article Number: 14
Published online on: 31 October 2025

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Sensitive cell‑free DNA assay for accurate detection of RAS and BRAF mutations in liquid biopsies of patients with metastatic colorectal cancer: Final results of the multicentric ColoBEAM study

Alexandre Harlé, Céline Gavoille, Olivier Bouché, Meher Ben Abdelghani, Jérome Plaza, Dominique Spaeth, Axelle Boudrant, François Ghiringhelli, Anne-Laure Villing, Christophe Borg, Marie Rouyer, Marie Husson, Pauline Gilson, Julia Salleron, Aurélien Lambert, Jean-Louis Merlin
Article Number: 13
Published online on: 30 October 2025

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Article

Single‑center retrospective study of factors associated with early discontinuation of tumor‑treating fields therapy in glioblastoma

Kohei Suzuki, Koichiro Sato, Shohei Nagasaka, Ryo Miyaoka, Takeshi Saito, Yoshiteru Nakano, Nayuta Higa, Toshiaki Akahane, Akihide Tanimoto, Ryosuke Hanaya, Junkoh Yamamoto
Article Number: 12
Published online on: 29 October 2025

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Clinical value of emerging peripheral blood protein biomarkers in prostate cancer (Review)

Mengli Chen, Feng Wang, Weixi Wang, Kangle Feng, Kaihua Xiang, Xubo Gong, Zhihua Tao, Weiwei Liu
Article Number: 11
Published online on: 29 October 2025

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Intratumoral and peritumoral radiomics of MRI predict pathological differentiation in patients with rectal cancer

Huanhui Liu, Hanjing Zhang, Qian Zou, Jianquan Yang
Article Number: 10
Published online on: 29 October 2025

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Retraction Open Access

[Retracted] Peritumoral activated hepatic stellate cells are associated with hepatic recurrence for resectable colorectal adenocarcinoma liver metastasis following resection

Li Deng, Taiyuan Li, Yuanyuan Liao, Shuang Liu, Zhen Xie, Zhixiang Huang, Hua Dai, Jianfeng Li, Xiong Lei
Article Number: 9
Published online on: 27 October 2025

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Case Report Open Access

Combined BRAF/MEK inhibition for BRAF‑mutant melanoma brain metastases in pregnancy: A case report

Jaroslav Melus, Michaela Jezberova, Silvia Mikulajova, Katarina Komaromy Gerincova, Martin Karlik, Igor Straka, Marek Krivosik, Peter Valkovic, Gabriela Timarova
Article Number: 8
Published online on: 24 October 2025

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Case Report Open Access

Synchronous rectal and endometrial cancer: A case report and literature review

Zhuofan Li, Li Peng, Qing Su, Beige Zong
Article Number: 7
Published online on: 24 October 2025

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Article

Predictive significance of thoracic skeletal muscle nutritional status for radiotherapy survival in elderly patients with esophageal squamous cell carcinoma

Shuqin Liu, Qi Li, Dongmei Luo, Caixia Jia, Dingqiang Peng, Guihong Liu
Article Number: 6
Published online on: 24 October 2025

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Review Open Access

Ribosome‑binding protein 1: A multidimensional regulator of cancer progression and a novel target for precision therapy (Review)

Ho Huang, Jia Ouyang
Article Number: 5
Published online on: 23 October 2025

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Case Report Open Access

Brain metastasis of ovarian cancer >20 years after initial diagnosis: A case report

Chihiro Ishizawa, Kazunari Miyazawa, Misaki Tani, Kazuaki Neriishi, Yukari Kambe, Akira Tsuchiya
Article Number: 4
Published online on: 23 October 2025

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Investigating the roles of microRNAs associated with cancer stem cells, drug resistance, metastasis and recurrence in hepatocellular carcinoma: A systematic review, network analysis and experimental verification

Yuanyuan Jiang, Xiaoning Zhu, Qinghua Peng, Paniz Zarghami Dastjerdi, Mengyun Peng, Ding Zheng, Xiaodong Wang, Yoke Kqueen Cheah, Jing Wang
Article Number: 3
Published online on: 23 October 2025

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Case Report Open Access

Advanced dual primary male breast cancer and lung cancer: A case report and literature review

Xiaoxiao Xing, Junyi Li, Yue Wang, Shiyun Zhang, Jun Li, Yun Wang, Dongpo Zhang, Daixiang Liao
Article Number: 2
Published online on: 22 October 2025

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Retraction Open Access

[Retracted] Tumor necrosis factor‑related apoptosis‑inducing ligand inhibits proliferation and induces apoptosis of prostate and bladder cancer cells

Lin Hao, Yan Zhao, Zhi-Gang Li, Hou-Guang He, Qing Liang, Zhi-Guo Zhang, Zhen-Duo Shi, Pei-Ying Zhang, Cong-Hui Han
Article Number: 1
Published online on: 22 October 2025

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Journal Cover
February-2026 Volume 31 Issue 2

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Case Report Open Access

Primary bone marrow diffuse large B‑cell lymphoma with secondary myelofibrosis: A case report

Jing Yang, Sheng-Ke Tu, Hui Peng, Yuan-Yuan Peng, Min Li, Kui Song
Article Number: 70
Published online on: 05 December 2025

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Tanshinone IIA targets RNF123 to inhibit non‑small cell lung cancer cell proliferation, migration and invasion via KAT2B‑mediated H3K18ac modification

Yongjie He, Yingxin Zhang, Jiangsheng Zhang, Kaican Cai
Article Number: 69
Published online on: 04 December 2025

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Expression profiling reveals coordinated dysregulation of autophagy‑associated proteins in marginal zone lymphoma and therapeutic implications

Jingshu Ruan, Xin Zhou, Ai Li, Ningning Shan
Article Number: 68
Published online on: 03 December 2025

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Analysis of the TCRβ repertoire characteristics when combining radiotherapy and immunotherapy in cancer

Xueli Yang, Wujun Wei, Zhihui Feng, Biao Zhang, Yi Liu, Fei Yang, Chong Zhang, Minglin Ou, Songbai Liao, Xianliang Hou
Article Number: 67
Published online on: 03 December 2025

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Identification and validation of critical mitochondrial hub genes for prostate cancer

Sha Liu, Liang Huang, Li Lin, Hong Shan, Yueming Wan
Article Number: 66
Published online on: 03 December 2025

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Roles of minimally invasive techniques in the management of epithelial ovarian cancer (Review)

Ruibing Yang, Jiali Gao, Yunyun Cheng, Caihong Lu, Juan Li
Article Number: 65
Published online on: 03 December 2025

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Case Report Open Access

Pregnancy with vitrified oocytes after fertility sparing surgery in a patient with fallopian tube cancer and a BRCA2 mutation: A case report and literature review

Guglielmo Stabile, Stefania Cicogna, Gabriella Zito, Anna Vido, Andrea Romano, Alessandro Mangogna, Luigi Nappi, Giuseppe Ricci
Article Number: 64
Published online on: 02 December 2025

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[Retracted] Clinical significance and effect of Sam68 expression in gastric cancer

Jinzhang Xiao, Qiuhong Wang, Qichang Yang, Hua Wang, Fulin Qiang, Song He, Jin Cai, Lei Yang, Yingying Wang
Article Number: 63
Published online on: 02 December 2025

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Genome‑wide CRISPR screening identifies CLDN1 as a central node in the anticancer mechanisms of berberine and as a therapeutic target in lung cancer

Xiaogang Wang, Benzhong Mi, Jinfeng Lv, Xin Tang, Jingyu Huang, Fei Liu, Yajing Xing, Xingjian Wen, Yongde Wang, Yadong Zhong
Article Number: 62
Published online on: 01 December 2025

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Construction of a human epidermal growth factor receptor 2‑related gene risk model for predicting breast cancer prognosis

Limin Huang, Chunhong Xu, Yining Song, Furong Sun, Xuemei Sun, Hanyi Yao, Mingchen Liu, Nan Luo
Article Number: 61
Published online on: 01 December 2025

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Development of a machine learning model for preoperative prediction of spread through air spaces in resectable 
non‑small cell lung cancer: A single‑center retrospective study

Chong Yang, Guozheng Ding, Bicheng Zhan, Lanlan Xuan, Feifei Cheng, Yanguo Yang
Article Number: 60
Published online on: 01 December 2025

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Integrated diagnostic evaluation of multiple malignant neoplasms via 99mTc‑MDP three‑phase bone imaging: A case report

Jing-Yi Lian, Jian-Lin Lu, Hui-Yu Zheng, Si-Xia Yuan, Jin-Shan Zhang
Article Number: 59
Published online on: 01 December 2025

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Article

Retrospective analysis of the association between monocyte percentage and outcomes in newly diagnosed diffuse large B‑cell lymphoma

Chaoqiang Zheng, Xiaoqin Xin
Article Number: 58
Published online on: 28 November 2025

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Role of HOXA transcript antisense RNA myeloid‑specific 1 in cancer (Review)

Yipei Jing, Xiaoqi Li, Ye Guo
Article Number: 57
Published online on: 28 November 2025

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Differential gene expression analysis reveals signaling pathways of proliferation, angiogenesis and metastasis is associated with interferon suppression in advanced hypopharyngeal cancer cells

Chia-Wei Kao, Yen-Ping Yeh, Ting-Wen Chen, Min-Ying Lin, Jyh-Der Leu, Yi-Jang Lee
Article Number: 56
Published online on: 27 November 2025

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Unicentric Castleman disease with paraneoplastic pemphigus and follicular dendritic cell sarcoma: A case report

Yukun Li, Fanchen Zeng, Zeyao Wang, Ganjian Zhao, Qi Zhou
Article Number: 55
Published online on: 27 November 2025

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CRISPR/Cas9‑mediated claudin‑2 knockout in HCT116 cells reveals its key role in colorectal cancer progression

Rana A. Alghamdi, Maryam H. Al‑zahrani
Article Number: 54
Published online on: 27 November 2025

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Comparative evaluation of microRNA detection in plasma, urine and liquid‑based cytology for high‑grade cervical intraepithelial neoplasia

Stéphanie Calfa, Ana Julia Aguiar De Freitas, Welinton Hirai, Júlio César Possati‑Resende, Rhafaela Lima Causin, Ricardo Dos Reis, Rui Manuel Reis, Márcia Maria Chiquitelli Marques
Article Number: 53
Published online on: 26 November 2025

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Case Report Open Access

Small intestinal SMARCA4‑deficient undifferentiated carcinoma with intussusception: A case report

Xiaoshan Cai, Shanshan Liu, Linqian Li, Yuming Zhang, Qin Guo, Ze Chen, Meihua Qu, Yubing Wang, Ben Yang, Xianwen Yue
Article Number: 52
Published online on: 26 November 2025

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Article Open Access

SENP5 acts as a downstream target of androgen receptor and contributes to prostate cancer growth

Ximin Chen, Xubo Gong, Jingcheng Zhang, Weiwei Liu
Article Number: 51
Published online on: 26 November 2025

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Retraction Open Access

[Retracted] Scutellarein suppresses Aβ‑induced memory impairment via inhibition of the NF‑κB pathway in vivo and in vitro

Xiao-Wei Huang, Yan Xu, Xin Sui, He Lin, Jia-Ming Xu, Dong Han, Dou-Dan Ye, Guang-Fu Lv, Yue-Xin Liu, Xiao-Bo Qu, Ming-Hua Duan
Article Number: 50
Published online on: 26 November 2025

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Prognostic analysis and expression patterns of programmed cell death ligand 1 and BRAF V600E in esophageal neuroendocrine carcinoma

Chengcheng Zhang, Li Zheng, Binwen Xu, Guidong Shi, Maoyong Fu
Article Number: 49
Published online on: 25 November 2025

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Article

Evaluating computer‑assisted mandibular reconstruction: Outsourced vs. in‑house approaches

Sho Katsura, Yoshihiro Morita, Ryotaro Kakimoto, Tetsuo Miyamoto, Kana Kashima, Emiko Ogasa, Yoshio Ueno, Ayano Tobe‑Nishimoto, Satoko Kishimoto, Yuka Matsumiya‑Matsumoto, Akinori Takeshita, Kazuhide Matsunaga, Narikazu Uzawa
Article Number: 48
Published online on: 25 November 2025

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Case Report Open Access

Multiple primary central nervous system lymphoma in the ventricular system and interpeduncular cistern: A case report

Qing Ouyang, Bing Sun, Haodong Sun, Jianing Luo, Zhen Xu, Yuan Ma
Article Number: 47
Published online on: 25 November 2025

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Review Open Access

Exploration of immunotherapy modalities in stage III unresectable non‑small cell lung cancer (Review)

Jiayun Ma, Jun Jiang
Article Number: 46
Published online on: 25 November 2025

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Case Report

Massive breast fat necrosis with invasive breast cancer: A case report

Anjie Zhang, Linfeng Song, Xiyao Yang, Xu Chen, Binlin Tian, Yongzhe Li, Guoyuan Jiang, Lin Jiang
Article Number: 45
Published online on: 25 November 2025

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