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Article

Hemithyroidectomy increases the risk of disease recurrence in patients with ipsilateral multifocal papillary thyroid carcinoma

  • Authors:
    • Xiaolong Li
    • Cui Zhao
    • Dandan Hu
    • Yang Yu
    • Jin Gao
    • Wenchuan Zhao
    • Ming Gao
  • View Affiliations / Copyright

    Affiliations: Department of Head and Neck Tumor, Tianjin Medical University Cancer Institute and Hospital, Tianjin 300060, P.R. China, School of Medicine and Dentistry, James Cook University, Douglas, Queensland 4878, Australia
  • Pages: 1412-1416
    |
    Published online on: February 19, 2013
       https://doi.org/10.3892/ol.2013.1202
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Abstract

Papillary thyroid carcinoma (PTC) is often clinically multifocal. In this study, the clinicopathological characteristics of a total of 347 PTC patients treated between 2006 and 2007 were investigated in order to assess the risk factors for tumor recurrence in patients with multifocal PTC. Of all the PTC cases reviewed, 35 (10%) were categorized as multifocal PTC. Patients with multifocal PTC were significantly more likely to have extrathyroidal extension, lymph node metastases and disease recurrence (P<0.05). Hemithyroidectomy resulted in a significantly higher incidence of tumor recurrence in patients with ipsilateral multifocal PTC compared with unifocal PTC patients (P<0.01). In conclusion, hemithyroidectomy was associated with tumor recurrence in patients with ipsilateral multifocal PTC but not those with unifocal PTC. Hemithyroidectomy should only be carried out after careful deliberation when involving patients with ipsilateral multifocal PTC.
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Copy and paste a formatted citation
Spandidos Publications style
Li X, Zhao C, Hu D, Yu Y, Gao J, Zhao W and Gao M: Hemithyroidectomy increases the risk of disease recurrence in patients with ipsilateral multifocal papillary thyroid carcinoma. Oncol Lett 5: 1412-1416, 2013.
APA
Li, X., Zhao, C., Hu, D., Yu, Y., Gao, J., Zhao, W., & Gao, M. (2013). Hemithyroidectomy increases the risk of disease recurrence in patients with ipsilateral multifocal papillary thyroid carcinoma. Oncology Letters, 5, 1412-1416. https://doi.org/10.3892/ol.2013.1202
MLA
Li, X., Zhao, C., Hu, D., Yu, Y., Gao, J., Zhao, W., Gao, M."Hemithyroidectomy increases the risk of disease recurrence in patients with ipsilateral multifocal papillary thyroid carcinoma". Oncology Letters 5.4 (2013): 1412-1416.
Chicago
Li, X., Zhao, C., Hu, D., Yu, Y., Gao, J., Zhao, W., Gao, M."Hemithyroidectomy increases the risk of disease recurrence in patients with ipsilateral multifocal papillary thyroid carcinoma". Oncology Letters 5, no. 4 (2013): 1412-1416. https://doi.org/10.3892/ol.2013.1202
Copy and paste a formatted citation
x
Spandidos Publications style
Li X, Zhao C, Hu D, Yu Y, Gao J, Zhao W and Gao M: Hemithyroidectomy increases the risk of disease recurrence in patients with ipsilateral multifocal papillary thyroid carcinoma. Oncol Lett 5: 1412-1416, 2013.
APA
Li, X., Zhao, C., Hu, D., Yu, Y., Gao, J., Zhao, W., & Gao, M. (2013). Hemithyroidectomy increases the risk of disease recurrence in patients with ipsilateral multifocal papillary thyroid carcinoma. Oncology Letters, 5, 1412-1416. https://doi.org/10.3892/ol.2013.1202
MLA
Li, X., Zhao, C., Hu, D., Yu, Y., Gao, J., Zhao, W., Gao, M."Hemithyroidectomy increases the risk of disease recurrence in patients with ipsilateral multifocal papillary thyroid carcinoma". Oncology Letters 5.4 (2013): 1412-1416.
Chicago
Li, X., Zhao, C., Hu, D., Yu, Y., Gao, J., Zhao, W., Gao, M."Hemithyroidectomy increases the risk of disease recurrence in patients with ipsilateral multifocal papillary thyroid carcinoma". Oncology Letters 5, no. 4 (2013): 1412-1416. https://doi.org/10.3892/ol.2013.1202
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