Neuroendocrine tumor in the liver of a patient with isolated polycystic liver disease: A case report and review of the literature

Koutsampasopoulos,Konstantinos; Antoniadou,Elisavet; Zoutis,Stavros; Iacovidis,Grigorios; Burova,Olga; Taplidis,Antonios

doi:10.3892/ol.2013.1233

May 2013 Volume 5 Issue 5

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May 2013 Volume 5 Issue 5

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Case Report

Neuroendocrine tumor in the liver of a patient with isolated polycystic liver disease: A case report and review of the literature

Authors:
- Konstantinos Koutsampasopoulos
- Elisavet Antoniadou
- Stavros Zoutis
- Grigorios Iacovidis
- Olga Burova
- Antonios Taplidis
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Affiliations: Department of Internal Medicine, General Hospital of Naoussa, Thessaloniki, Greece, Second Department of Pediatrics, Aristotle University of Thessaloniki, ‘AHEPA’ Hospital, Thessaloniki, Greece, Department of Radiology, General Hospital of Naoussa, Thessaloniki, Greece
Pages: 1664-1666
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Published online on: March 6, 2013

https://doi.org/10.3892/ol.2013.1233
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Abstract

Neuroendocrine tumors (NETs) frequently metastasize to the liver, but it is rare to find them there as primary tumors. Isolated polycystic liver disease (PCLD) is a rare autosomal dominant disease. There is no known association between polycystic liver disease and neuroendocrine or other tumors. We report a case of a 64-year-old female with a past medical history of isolated PCLD who presented with increasing abdominal pain over a two-week period. Our patient underwent open surgical biopsy one month after presentation. The histological examination and immunohistochemical findings suggested an intermediate grade neuroendocrine tumor. A 24-h delayed whole-body scintigraphy technique was utilized for the identification and localization of neuroendocrine tumors via the administration of In-111-labeled OctreoScan; however, no extrahepatic accumulation was observed. No previous studies in the literature describe a patient with PCLD and a primary or metastatic neuroendocrine tumor of the liver.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Neuroendocrine tumor in the liver of a patient with isolated polycystic liver disease: A case report and review of the literature

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