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Article

Gastrointestinal stromal tumours of the stomach: Cytological and immunocytochemical diagnostic features of two cases diagnosed by endoscopic ultrasound‑guided fine needle aspiration

  • Authors:
    • P. Todaro
    • S. F. Crinò
    • S. Pallio
    • C. Fazzari
    • P. Consolo
    • G. Tuccari
  • View Affiliations / Copyright

    Affiliations: Department of Human Pathology, University of Messina, University-Hospital Health Network ‘Polyclinic G. Martino’, Messina I-98125, Italy, Digestive Endoscopy Unit, University of Messina, University-Hospital Health Network ‘Polyclinic G. Martino’, Messina I-98125, Italy
  • Pages: 1862-1866
    |
    Published online on: April 10, 2013
       https://doi.org/10.3892/ol.2013.1296
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Abstract

The present study reports the diagnostic utility of endoscopic ultrasound‑guided fine needle aspiration (EUS‑FNAC) in two patients affected by gastrointestinal stromal tumours (GISTs) of the stomach. Clinically, the patients demonstrated skin pallor, melena, gastric discomfort and pain that had lasted three days or weeks. The cytological findings are discussed; these were strongly supported by immunocytochemical procedures that were performed on cell blocks and further confirmed following post‑surgical histopathological examination. The crucial aim of GIST management is to determine a correct diagnosis in early‑phase disease in order to realize an adequate curative surgical resection before the tumour becomes unresectable or metastatic. Moreover, a correct pre-surgical differential diagnosis of GISTs from other mesenchymal neoplasms may be easily made by EUS-FNAC, supported by cytological and immunocytochemical features.
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Copy and paste a formatted citation
Spandidos Publications style
Todaro P, Crinò SF, Pallio S, Fazzari C, Consolo P and Tuccari G: Gastrointestinal stromal tumours of the stomach: Cytological and immunocytochemical diagnostic features of two cases diagnosed by endoscopic ultrasound‑guided fine needle aspiration. Oncol Lett 5: 1862-1866, 2013.
APA
Todaro, P., Crinò, S.F., Pallio, S., Fazzari, C., Consolo, P., & Tuccari, G. (2013). Gastrointestinal stromal tumours of the stomach: Cytological and immunocytochemical diagnostic features of two cases diagnosed by endoscopic ultrasound‑guided fine needle aspiration. Oncology Letters, 5, 1862-1866. https://doi.org/10.3892/ol.2013.1296
MLA
Todaro, P., Crinò, S. F., Pallio, S., Fazzari, C., Consolo, P., Tuccari, G."Gastrointestinal stromal tumours of the stomach: Cytological and immunocytochemical diagnostic features of two cases diagnosed by endoscopic ultrasound‑guided fine needle aspiration". Oncology Letters 5.6 (2013): 1862-1866.
Chicago
Todaro, P., Crinò, S. F., Pallio, S., Fazzari, C., Consolo, P., Tuccari, G."Gastrointestinal stromal tumours of the stomach: Cytological and immunocytochemical diagnostic features of two cases diagnosed by endoscopic ultrasound‑guided fine needle aspiration". Oncology Letters 5, no. 6 (2013): 1862-1866. https://doi.org/10.3892/ol.2013.1296
Copy and paste a formatted citation
x
Spandidos Publications style
Todaro P, Crinò SF, Pallio S, Fazzari C, Consolo P and Tuccari G: Gastrointestinal stromal tumours of the stomach: Cytological and immunocytochemical diagnostic features of two cases diagnosed by endoscopic ultrasound‑guided fine needle aspiration. Oncol Lett 5: 1862-1866, 2013.
APA
Todaro, P., Crinò, S.F., Pallio, S., Fazzari, C., Consolo, P., & Tuccari, G. (2013). Gastrointestinal stromal tumours of the stomach: Cytological and immunocytochemical diagnostic features of two cases diagnosed by endoscopic ultrasound‑guided fine needle aspiration. Oncology Letters, 5, 1862-1866. https://doi.org/10.3892/ol.2013.1296
MLA
Todaro, P., Crinò, S. F., Pallio, S., Fazzari, C., Consolo, P., Tuccari, G."Gastrointestinal stromal tumours of the stomach: Cytological and immunocytochemical diagnostic features of two cases diagnosed by endoscopic ultrasound‑guided fine needle aspiration". Oncology Letters 5.6 (2013): 1862-1866.
Chicago
Todaro, P., Crinò, S. F., Pallio, S., Fazzari, C., Consolo, P., Tuccari, G."Gastrointestinal stromal tumours of the stomach: Cytological and immunocytochemical diagnostic features of two cases diagnosed by endoscopic ultrasound‑guided fine needle aspiration". Oncology Letters 5, no. 6 (2013): 1862-1866. https://doi.org/10.3892/ol.2013.1296
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