Male breast cancer arising in ectopic axillary breast tissue: A diagnostic dilemma

Xie,Yangchun; Huang,Jin; Xiao,Desheng; Zhong,Meizuo

doi:10.3892/ol.2013.1300

June 2013 Volume 5 Issue 6

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June 2013 Volume 5 Issue 6

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Article

Male breast cancer arising in ectopic axillary breast tissue: A diagnostic dilemma

Authors:
- Yangchun Xie
- Jin Huang
- Desheng Xiao
- Meizuo Zhong
View Affiliations / Copyright

Affiliations: Department of Oncology, Central South University Xiangya Hospital, Changsha, Hunan 410008, P.R. China, Department of Pathology, Central South University Xiangya Hospital, Changsha, Hunan 410008, P.R. China
Pages: 1931-1934
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Published online on: April 11, 2013

https://doi.org/10.3892/ol.2013.1300
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Abstract

Male breast cancer arising in ectopic axillary breast tissue is a rare occurrence and few cases have been reported in the literature. Due to its rarity, male axillary breast cancer is easy to misdiagnose. As for adenocarcinoma in the axilla, it is difficult to identify whether the origin is the mammary tissue or the skin appendages, particularly in cases where there is a poor differentiation. The present study reports the case of a male patient with a right axillary lesion that had been present for 6 months. A histological evaluation revealed the features of a poorly-differentiated adenocarcinoma with regards to the pathological report. The patient was diagnosed with a metastatic adenocarcinoma with unknown primary origin. However, following 4 cycles of intensive chemotherapy, the patient experienced bone metastasis while the local lesion was in partial remission. Further immunohistochemistry confirmed its mammary origin. There is limited literature relating to male ectopic axillary breast cancer, and a high probability of misdiagnosis of this disease.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Male breast cancer arising in ectopic axillary breast tissue: A diagnostic dilemma

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Abstract

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