Transformed lymphoplasmacytic lymphoma involving the main carina: A case report

Nakao,Makoto; Oguri,Tetsuya; Miyazaki,Mikinori; Hijikata,Hisatoshi; Yokoyama,Midori; Kunii,Eiji; Uemura,Takehiro; Takakuwa,Osamu; Ohkubo,Hirotsugu; Maeno,Ken; Niimi,Akio

doi:10.3892/ol.2013.1369

Transformed lymphoplasmacytic lymphoma involving the main carina: A case report

Authors:
- Makoto Nakao
- Tetsuya Oguri
- Mikinori Miyazaki
- Hisatoshi Hijikata
- Midori Yokoyama
- Eiji Kunii
- Takehiro Uemura
- Osamu Takakuwa
- Hirotsugu Ohkubo
- Ken Maeno
- Akio Niimi
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Affiliations: Department of Medical Oncology and Immunology, Nagoya City University, School of Medical Sciences, Nagoya, Aichi 467-8601, Japan
Published online on: May 29, 2013 https://doi.org/10.3892/ol.2013.1369
Pages: 542-544

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Abstract

A 41-year-old male was admitted to Nagoya City University Hospital subsequent to experiencing a cough with bloody sputum for a few days. The patient had a 4-year history of lymphoplasmacytic lymphoma (LPL) and had achieved a good partial response to anticancer chemotherapy. Chest computed tomography (CT) showed an endobronchial tumor of the main carina. A bronchoscopy revealed an exophytic tumor at the main carina, and autofluorescence imaging bronchovideoscopy showed that the tumor and surrounding area were magenta in color. The biopsy specimens demonstrated that the endobronchial tumor was composed of large atypical lymphoid cells. The patient was diagnosed with a high-grade transformation of LPL. In addition to describing a rare case of transformed LPL involving the main carina, the present study also summarizes and discusses endobronchial lymphomas, with a brief review of a number of published studies.

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