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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
August 2013 Volume 6 Issue 2

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Review

Endocrine resistance in breast cancer: Current status and a perspective on the roles of miRNAs (Review)

Jichun Zhou, Rongyue Teng, Qinchuan Wang, Chenpu Xu, Jufeng Guo, Chao Yuan, Jianguo Shen, Wenxian Hu, Linbo Wang, Shuduo Xie
Pages: 295-305
Published online on: 17 June 2013

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Review

A new emergency in oncology: Bone metastases in breast cancer patients (Review)

Toni Ibrahim, Laura Mercatali, Dino Amadori
Pages: 306-310
Published online on: 04 June 2013

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Review

Oxygen metabolism in oral cancer: HIF and GLUTs (Review)

Karuza Maria Alves Pereira, Filipe Nobre Chaves, Thales Salles Angelim Viana, Francisco Samuel Rodrigues Carvalho, Fábio Wildson Gurgel Costa, Ana Paula Negreiros Nunes Alves, Fabrício Bitu Sousa
Pages: 311-316
Published online on: 03 June 2013

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Review

Epigenetic regulation of the human telomerase reverse transciptase gene: A potential therapeutic target for the treatment of leukemia (Review)

Xinbing Sui, Na Kong, Zhanggui Wang, Hongming Pan
Pages: 317-322
Published online on: 29 May 2013

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Article

Effect of in vivo administration of reprogramming factors in the mouse liver

Akira Tomokuni, Hidetoshi Eguchi, Hiromitsu Hoshino, Dyah Laksmi Dewi, Shinpei Nishikawa, Yoshihiro Kano, Norikatsu Miyoshi, Arinobu Tojo, Seiichiro  Kobayashi, Noriko Gotoh, Kunihiko Hinohara, Noemi Fusaki, Toshiyuki Saito, Hiroshi Suemizu, Hiroshi Wada, Shogo Kobayashi, Shigeru Marubashi, Masahiro Tanemura, Yuichiro Doki, Masaki Mori, Hideshi Ishii, Hiroaki Nagano
Pages: 323-328
Published online on: 20 June 2013

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Article

ER‑α36‑mediated gastric cancer cell proliferation via the c‑Src pathway

Xuming Wang, Hao Deng, Feng Zou, Zhenqi Fu, Ying  Chen, Zhaoyi Wang, Lijiang Liu
Pages: 329-335
Published online on: 20 June 2013

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Case Report

Detection of intravenous leiomyomatosis with intracardiac extension by ultrasonography: A case report

Wei Liu, Ming Liu, Jing Xue
Pages: 336-338
Published online on: 10 June 2013

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Article

Reduced expression of Snail decreases breast cancer cell motility by downregulating the expression and inhibiting the activity of RhoA GTPase Retraction in /10.3892/ol.2025.15143

Ali Zhang, Quansheng Wang, Zhiqiang Han, Wei Hu, Ling Xi, Qinlei Gao, Shixuan Wang, Jianfeng Zhou, Gang Xu, Li Meng, Gang Chen, Ding Ma
Pages: 339-346
Published online on: 07 June 2013

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Article

Melatonin treatment increases the transcription of cell proliferation-related genes prior to inducing cell death in C6 glioma cells in vitro

Jiagui Qu, Joshua D. Rizak, Xiaomiao Li, Jiejing Li, Yuanye Ma
Pages: 347-352
Published online on: 18 June 2013

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Article

Screening for differentially expressed genes between left‑ and right‑sided colon carcinoma by microarray analysis

Hong Zhu, Tian‑Cong Wu, Wei‑Qiong Chen, Li‑Jun Zhou, Yue Wu, Liang Zeng, Hai‑Ping Pei
Pages: 353-358
Published online on: 18 June 2013

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Article

miR‑223 functions as a potent tumor suppressor of the Lewis lung carcinoma cell line by targeting insulin‑like growth factor‑1 receptor and cyclin-dependent kinase 2

Weiqi Nian, Xujun Ao, Yongzhong Wu, Yi Huang, Jianghe Shao, Yiming Wang, Zhengtang Chen, Fanglin Chen, Donglin Wang
Pages: 359-366
Published online on: 04 June 2013

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Article

Effect of shRNA‑mediated inhibition of Nanog gene expression on the behavior of human gastric cancer cells

Wen Ji, Zheng Jiang
Pages: 367-374
Published online on: 13 June 2013

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Article

Expression and clinical significance of the Trop‑2 gene in advanced non‑small cell lung carcinoma

Aigui Jiang, Xiaoyan Gao, Degeng Zhang, Lixin Zhang, Huiyu Lu
Pages: 375-380
Published online on: 29 May 2013

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Article

Prognostic significance of p21, p27 and survivin protein expression in patients with oral squamous cell carcinoma

Mingbin Zhang, Jiang Li, Lizhen Wang, Zhen Tian, Ping Zhang, Qin Xu, Chenping Zhang, Fengcai Wei, Wantao Chen
Pages: 381-386
Published online on: 07 June 2013

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Article

Gene expression of bone morphogenic protein 8B in the primary site, peripheral blood and bone marrow of patients with gastric cancer

Kosuke Mima, Takeo Fukagawa, Junji Kurashige, Yuki Takano, Ryutaro Uchi, Hiroki Ueo, Tae Matsumura, Masahisa Ishibashi, Genta Sawada, Yusuke Takahashi, Sayuri Akiyoshi, Hidetoshi Eguchi, Tomoya Sudo, Keishi Sugimachi, Masayuki Watanabe, Hideshi Ishii, Masaki Mori, Hideo Baba, Mitsuru Sasako, Koshi Mimori
Pages: 387-392
Published online on: 12 June 2013

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Article

A potential diagnostic marker for ovarian cancer: Involvement of the histone acetyltransferase, human males absent on the first Corrigendum in /10.3892/ol.2026.15526

Ning Liu, Rui Zhang, Xiaoming Zhao, Jiaming Su, Xiaolei Bian, Jinsong Ni, Ying Yue, Yong Cai, Jingji Jin
Pages: 393-400
Published online on: 07 June 2013

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Article

TGFβ1 and HGF protein secretion by esophageal squamous epithelial cells and stromal fibroblasts in oesophageal carcinogenesis

Zhibin Xu, Shijie Wang, Mingli Wu, Weiwei Zeng, Xiaoling Wang, Zhiming Dong
Pages: 401-406
Published online on: 18 June 2013

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Article

Atrial natriuretic peptide modulates the proliferation of human gastric cancer cells via KCNQ1 expression

Jia Zhang, Zhilong Zhao, Chao Zu, Haijian Hu, Hui Shen, Mingxin Zhang, Jiansheng Wang
Pages: 407-414
Published online on: 25 June 2013

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Article

Tumor angiogenesis, macrophages and mast cell microdensities in endometrioid endometrial carcinoma

Cristiana Simionescu, Claudiu Mărgăritescu, Alex Stepan, Daniel Pirici, Raluca Ciurea, Nicolae Cernea
Pages: 415-420
Published online on: 18 June 2013

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Article

A GWAS‑identified susceptibility locus on chromosome 11q13.3 and its putative molecular target for prediction of postoperative prognosis of human renal cell carcinoma

Tong Su, Yifang Han, Yongwei Yu, Xiaojie Tan, Xiaopan Li, Jianguo Hou, Yan Du, Jian Shen, Guoping Wang, Liye Ma, Shuang Jiang, Hongwei Zhang, Guangwen Cao
Pages: 421-426
Published online on: 25 June 2013

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Article

Arterial interventional chemotherapy and IMRT with concurrent chemotherapy for nasopharyngeal carcinoma with intracranial involvement

Xinglai Fen, Weifeng Qin, Wuan Bao, Feng Jiang, Bin Li, Fujun Hu, Xiaozhong Chen
Pages: 427-431
Published online on: 17 June 2013

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Article

Blockade of NF-κB nuclear translocation results in the inhibition of the invasiveness of human gastric cancer cells

Zhi-Min Li, Yu-Wei Pu, Bao-Song Zhu
Pages: 432-436
Published online on: 11 June 2013

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Article

Mutational analysis of the GNA11, MMP27, FGD1, TRRAP and GRM3 genes in thyroid cancer

Avaniyapuram Kannan Murugan, Chongfei Yang, Mingzhao Xing
Pages: 437-441
Published online on: 11 June 2013

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Case Report

Hamartoma of the breast in two patients: A case report

Fatma Cavide Sonmez, Zuhal Gucin, Pelin Yildiz, Zeynep Tosuner
Pages: 442-444
Published online on: 29 May 2013

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Case Report

Sudden visual loss in the untreated eye of a patient with neovascular glaucoma following an intravitreal bevacizumab injection: A case report

Ding Xu, Liumei Hu, Bing Wang, Fang Wang
Pages: 445-447
Published online on: 07 June 2013

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Case Report

Fluid biopsy for circulating tumor cells in an occult ovarian cancer patient exhibiting bilateral supraclavicular lymph node metastases: A case report

Shizhi He, Pingdong Li, Xiaohong Chen, Zhenkun Yu
Pages: 448-452
Published online on: 24 May 2013

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Article

Quercetin liposomes protect against radiation‑induced pulmonary injury in a murine model

Hao Liu, Jian‑Xing Xue, Xing Li, Rui Ao, You Lu
Pages: 453-459
Published online on: 29 May 2013

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Case Report

Giant primary retroperitoneal teratoma in an adult female patient: A case report

Xiao Huang, Ben Liu, Liping Xie
Pages: 460-462
Published online on: 04 June 2013

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Article

Reduced expression of Rho GDP dissociation inhibitor 2 mRNA is associated with lymph node metastasis in gastric carcinoma

Atsuo Shida, Shuichi Fujioka, Naoto Takahashi, Hiroaki Aoki, Tomoyoshi Okamoto, Norio Mitsumori, Nobuo Omura, Katsuhiko Yanaga
Pages: 463-467
Published online on: 06 June 2013

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Article

MicroRNA‑92 regulates cervical tumorigenesis and its expression is upregulated by human papillomavirus‑16 E6 in cervical cancer cells

Yu Yu, Yao Zhang, Shulan Zhang
Pages: 468-474
Published online on: 17 June 2013

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Article

Inhibition of cell migration by ouabain in the A549 human lung cancer cell line

Ning Liu, Yali Li, Suwen Su, Na Wang, Huici Wang, Junxia Li
Pages: 475-479
Published online on: 17 June 2013

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Article

RECIST 1.1 and serum thyroglobulin measurements in the evaluation of responses to sorafenib in patients with radioactive iodine‑refractory differentiated thyroid carcinoma

Maomei Ruan, Yan Shen, Libo Chen, Minghua Li
Pages: 480-486
Published online on: 25 June 2013

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Case Report

Osteolytic myxopapillary ependymoma with marked hyaline degeneration in a 72‑year‑old male: A case report

Hai Wang, Zhiyuan Zhang, Mohammad Shahidul Makki, Qunli Shi
Pages: 487-489
Published online on: 14 June 2013

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Article

TIM-3 expression in human osteosarcoma: Correlation with the expression of epithelial‑mesenchymal transition-specific biomarkers

Yongjun Shang, Zhanyong Li, Hong Li, Haibo Xia, Zhenhua Lin
Pages: 490-494
Published online on: 18 June 2013

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Article

Sonoporation by low‑frequency and low‑power ultrasound enhances chemotherapeutic efficacy in prostate cancer cells in vitro

Yu Wang, Wen‑Kun Bai, E. Shen, Bing Hu
Pages: 495-498
Published online on: 10 June 2013

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Article

Pituitary protein 7B2 plasma levels in patients with liver disease: Comparisons with other hormones and neuropeptides

Maria S. Venetikou, Luke Meleagros, Mohhammad A. Ghatei, Stephen R. Bloom
Pages: 499-506
Published online on: 07 June 2013

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Article

miR‑222 is upregulated in epithelial ovarian cancer and promotes cell proliferation by downregulating P27kip1

Chaoyang Sun, Na Li, Bo Zhou, Zongyuan Yang, Dong Ding, Danhui Weng, Li Meng, Shixuan Wang, Jianfeng Zhou, Ding Ma, Gang Chen
Pages: 507-512
Published online on: 13 June 2013

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Article

Sarcomatoid carcinoma of the renal pelvis: Experience of multiple cases over a ten‑year period

Shanwen Chen, Geming Chen, Dan Xia, Jun Li, Shuo Wang, Baihua Shen, Baiye Jin
Pages: 513-516
Published online on: 13 June 2013

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Article

Matrine effectively inhibits the proliferation of breast cancer cells through a mechanism related to the NF‑κB signaling pathway

Hongmin Shao, Baowen Yang, Rongrong Hu, Yingying Wang
Pages: 517-520
Published online on: 14 June 2013

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Article

Deleted in liver cancer‑1 inhibits cell growth and tumorigenicity in human pancreatic cancer

Zhenjiang Zheng, Chunlu Tan, Guangming Xiang, Gang Mai, Xubao Liu
Pages: 521-524
Published online on: 18 June 2013

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Article

Synergy of Taxol and rhein lysinate associated with the downregulation of ERK activation in lung carcinoma cells

Yong‑Zhan Zhen, Gang Hu, Yu‑Fang Zhao, Feng Yan, Ran Li, Jun‑Ling Gao, Ya‑Jun Lin
Pages: 525-528
Published online on: 14 June 2013

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Article

Changes in sex hormone levels after radical prostatectomy: Results of a longitudinal cohort study

Mauro Gacci, Nicola Tosi, Gianni Vittori, Andrea Minervini, Giovanni  Corona, Tommaso Cai, Anna Maria Morelli, Linda Vignozzi, Sergio Serni, Mario Maggi, Marco Carini
Pages: 529-533
Published online on: 21 June 2013

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Case Report

CyberKnife therapy of 24 multiple brain metastases from lung cancer: A case report

Guiqing Yang, Yishan Wang, Yuanyuan Wang, Sixiang Lin, Dongning Sun
Pages: 534-536
Published online on: 07 June 2013

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Article

Immune response, clinical outcome and safety of dendritic cell vaccine in combination with cytokine‑induced killer cell therapy in cancer patients

Yu Cui, Xuejing Yang, Wei Zhu, Jiali Li, Xiaojing Wu, Yan Pang
Pages: 537-541
Published online on: 04 June 2013

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Case Report

Transformed lymphoplasmacytic lymphoma involving the main carina: A case report

Makoto Nakao, Tetsuya Oguri, Mikinori Miyazaki, Hisatoshi Hijikata, Midori Yokoyama, Eiji Kunii, Takehiro Uemura, Osamu Takakuwa, Hirotsugu Ohkubo, Ken Maeno, Akio Niimi
Pages: 542-544
Published online on: 29 May 2013

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Article

Serum vascular endothelial growth factor‑C levels: A possible diagnostic marker for lymph node metastasis in patients with primary non‑small cell lung cancer

Yakun Zhang, Xue Meng, Hongsheng Zeng, Yan Guan, Qiong  Zhang, Shen Guo, Xiujiu Liu, Qisen Guo
Pages: 545-549
Published online on: 04 June 2013

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Case Report

Inflammatory pseudotumor mimicking primary hepatic malignant tumor with hepatitis B virus-related cirrhosis: A case report

Qinghong Ke, Le Fan, Xin Duan, Zenglei He, Shusen Zheng
Pages: 550-552
Published online on: 10 June 2013

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Case Report

Small cell lung cancer with endobronchial growth: A case report

Koichi Kurishima, Katsunori Kagohashi, Kunihiko Miyazaki, Tomohiro Tamura, Gen Ohara, Mio Kawaguchi, Hiroaki Satoh
Pages: 553-555
Published online on: 25 June 2013

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Article

Small compound 6‑O‑angeloylplenolin induces caspase‑dependent apoptosis in human multiple myeloma cells

Ying Liu, Ying Dong, Bo Zhang, Yong‑Xian Cheng
Pages: 556-558
Published online on: 30 May 2013

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Article

Bcl‑2 correlates with localization but not outcome in human osteosarcoma

Klemens Trieb, Irene Sulzbacher, Bernd Kubista
Pages: 559-561
Published online on: 13 June 2013

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Case Report

Perforated sarcomatoid carcinoma of the jejunum: Case report

Ning Han, Qing‑Hui Han, Yang‑Zhou Liu, Zeng‑Chun Li, Jiao Li
Pages: 562-564
Published online on: 06 June 2013

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Case Report

Primary desmoplastic small round cell tumor of the testis: A case report and review of the literature

Lang He, Shimin Wen, Xin Hu, Cuihua Guo, Cheng Yi
Pages: 565-567
Published online on: 25 June 2013

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Case Report

Laparoscopic left pancreatectomy for pancreatic sarcomatoid carcinoma: A case report and review of the literature

Jie Yao, Jian-Jun Qian, Chang-Ren Zhu, Dou-Sheng Bai, Yi Miao
Pages: 568-570
Published online on: 18 June 2013

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Article

TIPE2 mRNA overexpression correlates with TNM staging in renal cell carcinoma tissues

Zongliang Zhang, Haiyan Qi, Sichuan Hou, Xunbo Jin
Pages: 571-575
Published online on: 10 June 2013

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Article

Colorectal cancer screening with fecal occult blood test: A 22‑year cohort study

Peng Jin, Zi‑Tao Wu, Shi‑Rong Li, Shu‑Jun Li, Ji‑Heng Wang, Zhi‑Hong Wang, Jian‑Guo Lu, Xin‑Juan Cui, Ying Han, Jianyu Rao, Jian‑Qiu Sheng
Pages: 576-582
Published online on: 14 June 2013

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Article

Role of the ROS/AMPK signaling pathway in tetramethylpyrazine-induced apoptosis in gastric cancer cells

Bo Yi, Dan Liu, Ming He, Qiyun Li, Tiande Liu, Jianghua Shao
Pages: 583-589
Published online on: 14 June 2013

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Case Report

Complete regression of advanced prostate cancer for ten years: A case report and review of the literature

Bing Yan, Xianze Meng, Xiaowei Wang, Pinkang Wei, Zhifeng Qin
Pages: 590-594
Published online on: 06 June 2013

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Article

Antimutagenic activity and preventive effect of black tea on buccal mucosa cancer

Yu Qian, Kai Zhu, Qiang Wang, Guijie Li, Xin Zhao
Pages: 595-599
Published online on: 14 June 2013

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Article

Nicotinamide‑mediated inhibition of SIRT1 deacetylase is associated with the viability of cancer cells exposed to antitumor agents and apoptosis

Tong Wang, Huixia Cui, Nan Ma, Youhong Jiang
Pages: 600-604
Published online on: 14 June 2013

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Article

Efficacy of sorafenib in patients with gastrointestinal stromal tumors in the third‑ or fourth‑line treatment: A retrospective multicenter experience

Umut Kefeli, Mustafa Benekli, Alper Sevinc, Ramazan Yildiz, Muhammed   Ali Kaplan, Aydin Ciltas, Ozan Balakan, Abdurrahman Isikdogan, Ugur Coskun, Faysal  Dane, Hakan Harputluoglu, Halit Karaca, Dogan Yazilitas, Ayse Durnali, Ali  Osman Kaya, Umut Demirci, Mahmut Gumus, Suleyman Buyukberber
Pages: 605-611
Published online on: 17 June 2013

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Case Report

Combining angioplasty with percutaneous microwave ablation for treating primary Budd‑Chiari syndrome associated with hepatocellular carcinoma in two patients: A case report

Qing‑Qiao Zhang, Mao‑Heng Zu, Hao Xu, Yu‑Ming Gu, Wen‑Liang Wang, Zhi‑Kang Gao
Pages: 612-616
Published online on: 20 June 2013

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Article

Roles of mitochondrial transcription factor A and microRNA‑590‑3p in the development of bladder cancer

Miao Mo, Fenghua Peng, Lu Wang, Longkai Peng, Gongbin Lan, Shaojie Yu
Pages: 617-623
Published online on: 21 June 2013

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Journal Cover
June-2026 Volume 31 Issue 6

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Early postoperative complications and patient‑reported quality of life following breast‑conserving surgery with intraoperative radiotherapy: A prospective cohort study

Hongmei Han, Xuwen Liu, Baozhong Zhang, Jingjing Liu, Jing Wang, Qingsong Pang
Article Number: 268
Published online on: 27 April 2026

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Exploring the mechanism of action of glaucocalyxin D against acute myeloid leukemia using network pharmacology, molecular docking and cellular experiments

Lian Chen, Weixian Yang, Weiqing Zhang, Heng Luo, Chen Yan
Article Number: 267
Published online on: 27 April 2026

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Special Issue

Advances in cerebrospinal fluid biomarkers for the diagnosis, treatment and monitoring of leptomeningeal metastases (Review)

Huaixu Li, Wenwen Fan, Fengchun Mu, Cheng Fang, Ting Xiao, Jinghai Wan, Hongqing Cai
Article Number: 266
Published online on: 27 April 2026

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Article Open Access

Exploration of the effect and mechanism of Eclipta prostrata L. against gastric cancer based on network pharmacology and experimental verification

Weizhou Yu, Xiaohui Ni, Jing Wang, Wei Xia, Xinya Shen, Fan Qiu, Yuping Chen
Article Number: 265
Published online on: 27 April 2026

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Article Open Access

Neoadjuvant radiotherapy for resectable hepatocellular carcinoma with vascular invasion: A systematic review and meta‑analysis

Yuhao Su, Yuxin Liang, Deyuan Zhong, Hongtao Yan, Qinyan Yang, Xiaolun Huang
Article Number: 264
Published online on: 27 April 2026

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Article Open Access

Computational discovery of novel colony‑stimulating factor‑1 receptor as a potential therapeutic biomarker in osteosarcoma and a novel inhibitor from herbal sources

Hui Zhang, Shiwei Wu, Dan Luo, Jincai Guo
Article Number: 263
Published online on: 24 April 2026

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Article Open Access

Effect of the use of hormonal replacement therapy on breast cancer prognosis: A systematic review and meta‑analysis

Javier Angel Canelas Fernández, Jéssica Alonso‑molero, Paz Rodríguez‑cundín, Javier Llorca, Inés Gómez‑aceb, Trinidad Dierssen‑sotos
Article Number: 262
Published online on: 24 April 2026

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Article Open Access

Evaluation of smoking status as a prognostic factor under immune checkpoint inhibitor treatment: A single center analysis

Christoph Schaefers, Annika Poch, Anika Forstreuter, Frederike Bokemeyer, Carsten Bokemeyer, Christoph Seidel
Article Number: 261
Published online on: 24 April 2026

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Correction Open Access

[Corrigendum] CDDO, a PPAR‑γ ligand, inhibits TPA‑induced cell migration and invasion through a PPAR‑γ‑independent mechanism

Hye-Yeon Jang, On-Yu Hong, Hyun Jo Youn, Jaeuk Jung, Eun Yong Chung, Sung Hoo Jung, Jong-Suk Kim
Article Number: 260
Published online on: 24 April 2026

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Review Open Access

Dual roles of neutrophil extracellular traps in tumors: From pro‑metastatic mechanisms to immunotherapeutic strategies (Review)

Mingxin Guo, Han Wang, Jiaqi Zeng, Ning Wu, Zhiqiang Hu, Ao Xue, Ting Dai
Article Number: 259
Published online on: 23 April 2026

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Review Open Access

Emerging role of protein arginine methyltransferase 5 in gastrointestinal cancer (Review)

Rui Zhang, Yiwen Lu, Xiaohua Fang, Fengquan Zhang, Weidong Wu, Jie Song, Zhenzhen Liang
Article Number: 258
Published online on: 23 April 2026

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Case Report Open Access

Adjuvant immunotherapy plus chemotherapy and maintenance immunotherapy for pulmonary lymphoepithelioma‑like carcinoma with hepatitis B virus infection, KRAS mutation and high expression of programmed death ligand 1: A case report

Jing Zhu, Qing-Gui Xu, Jiao Zhu, Rui-Xiang Zhou, Yu-Chuan Zhou, Zhi-Ke Li
Article Number: 257
Published online on: 22 April 2026

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Retraction Open Access

[Retracted] Interleukin‑17 promotes the development of cisplatin resistance in colorectal cancer

Guolong Sui, Yingna Qiu, Haijuan Yu, Qingbin Kong, Baowen Zhen
Article Number: 256
Published online on: 22 April 2026

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Article Open Access

An m6A‑programmed cell death signature predicts prognosis and identifies STK25 as a therapeutic target in colon adenocarcinoma

Hezhi Yu, Tihui Li, Xiaoyun Huang, Zihan Chen, Zixiang Lin, Fenglin Chen
Article Number: 255
Published online on: 22 April 2026

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Article Open Access

METTL5 reprograms glycolytic metabolism and promotes non‑small cell lung cancer progression by modifying PGAM1

Yuchen Shan, Xiaoyu Duan, Kai Yuan, Ming Lou, Qiyong Wu, Zhaojia Gao
Article Number: 254
Published online on: 20 April 2026

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Article Open Access

Clinical features and outcomes of peripheral T‑cell lymphoma, not otherwise specified: A single institution retrospective analysis of 30 cases

Meng-Xue Ma, Ya-Li Zhang, Li-Na Xing, Qiu-Yi Wang, Shukai Qiao
Article Number: 253
Published online on: 20 April 2026

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Article Open Access

BUD23 is associated with malignancy and correlates with immune infiltration in NSCLC

Yonghuang Tan, Jun Ma, Jiangli Zhou, Jianjun Lu
Article Number: 252
Published online on: 20 April 2026

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Article Open Access

Evaluation of NID2 and CDO1 methylation for ovarian cancer screening

Shuilian Wu, Jing Jin, Yuanyuan Cao, Xiaofan He, Qiang Hou, Mingfeng Jiang
Article Number: 251
Published online on: 20 April 2026

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Retraction Open Access

[Retracted] Improved ataxia telangiectasia mutated kinase inhibitor KU60019 provides a promising treatment strategy for non‑invasive breast cancer

Ying Zhu, Changfei Mao, Jianzhong Wu, Shuchun Li, Rong Ma, Haixia Cao, Minghua Ji, Changwen Jing, Jinhai Tang
Article Number: 250
Published online on: 20 April 2026

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Case Report Open Access

Fever and leukemoid reaction in bladder cancer: A case report

Tianrun Huang, Jiguo Xu, Yuwei He, Yu Shen, Chenlong Chu, Jingyuan Lu, Parehe Alimu, Chunlei Chen, Jianhe Liu
Article Number: 249
Published online on: 20 April 2026

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Article Open Access

Prognostic effect and prognostic factors of TACE for the treatment of unresectable hepatocellular carcinoma: Propensity score matching analysis

Liangliang Zhang, Cancan Li, Hui Guo, Xue Zhang, Wei Liu, Xing Xu
Article Number: 248
Published online on: 16 April 2026

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Expression of Concern Open Access

[Expression of Concern] Long non‑coding RNA BX357664 inhibits cell proliferation and metastasis in human lung cancer

Shu-Hui Xiao, Gong-Xiang Li, Lingli Quan
Article Number: 247
Published online on: 16 April 2026

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Article

Safety and feasibility of total neoadjuvant FLOT chemotherapy in locally‑advanced gastric and gastroesophageal junction cancer

Oleksii Dobrzhanskyi, Andrii Horodetskyi, Mykyta Pepenin, Yurii Kondratskyi
Article Number: 246
Published online on: 16 April 2026

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Article Open Access

Vasculogenic mimicry and breast cancer prognosis: Insights into predictive model development

Zhifeng Wu, Yueyue Teng, Shengchao Huang, Shiming Shi, Pu Qiu, Leyao Shan, Meihua Lin, Yuanqi Zhang
Article Number: 245
Published online on: 15 April 2026

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Article Open Access

Effect and safety analysis of raltitrexed peritoneal perfusion in patients with intermediate and advanced colorectal cancer

Yanhua Wan, Xiaoyun Dai, Liang Chao
Article Number: 244
Published online on: 15 April 2026

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Article Open Access

Mechanism of action of alkaloids in Fritillaria‑induced autophagy and apoptosis in non‑small cell lung cancer

Mengru Teng, Mengrui Zhang, Jun He, Wai Ming Tse, Kathy Wai Gaun Tse, Chengwu Liu, Bengui Ye
Article Number: 243
Published online on: 15 April 2026

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Article Open Access

Identification of a prognostic model using immune related genes combined with tumour mutational burden and T cell infiltration in triple‑negative breast cancer

You Meng, Ze-Xin Han, Jie Zhu, Ying Wang, Yue-Qing Huang, Zhong-Hua Zou, Yu-Yuan Ma, Yi-Fan Li, Han Wang, Ying Li, Lian Lian, Wen-Jie Wang
Article Number: 242
Published online on: 15 April 2026

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Correction Open Access

[Corrigendum] Silencing glioma‑associated oncogene homolog 1 suppresses the migration and invasion of hepatocellular carcinoma in vitro

Zeming Hu, Fangfang Xie, Ang Hu, Mengjing Xu, Yuwen Liu, Jiankang Zhang, Jianbo Xiao, Yunlei Song, Jianing Zhong, Bin Chen
Article Number: 241
Published online on: 15 April 2026

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Article

A novel inflammation and tumor marker‑based prognostic score, neutrophil‑lymphocyte ratio‑C‑reactive protein‑Ca19‑9, in metastatic gastric cancer

Berkan Karabuğa, Osman Bilge Kaya, Ekin Konca Karabuğa, Ergin Aydemir, Mehmet Emin Yilmaz, Sedef Tatar Bolat, Ayşegül Uçkun, Enes Kaptan, Öztürk Ateş, Mustafa Büyükkör
Article Number: 240
Published online on: 15 April 2026

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Article Open Access

KRAS (G12D)‑selective inhibitor MRTX1133 suppresses proliferation and differentially modulates chemosensitivity in ovarian mucinous carcinoma

Ryota Watano, Hiroaki Mizukami, Yasushi Saga
Article Number: 239
Published online on: 15 April 2026

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Article

Intensity‑ and time‑dependent anticancer effects of alternating electric fields in non‑small cell lung cancer cell lines

Jinju Heo, Myonggeun Yoon
Article Number: 238
Published online on: 15 April 2026

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Review Open Access

KLF family of proteins in gastrointestinal tumors (Review)

Jingjing Zhang, Rupu Zhao, Pengjie Yang, Yong Zhu, Benben Zhu
Article Number: 237
Published online on: 15 April 2026

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Article

Establishment and validation of a diagnostic model for evaluating synchronous liver metastasis in pancreatic cancer using comprehensive blood biochemical indicators

Yiyi Jiang, Gaoyao Peng, Songqing He, Jiangfa Li
Article Number: 236
Published online on: 14 April 2026

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Review Open Access

Soluble isoforms of EGFR family in breast cancer: Advances and clinical relevance (Review)

Peng Yang, Xinnong Jiang, Fangguo He
Article Number: 235
Published online on: 14 April 2026

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Article Open Access

Thrombospondin‑1 triggers calreticulin expression in human mucoepidermoid carcinoma MC‑3 cells via the PERK/CHOP pathway

Shengwei Bao, Yuanyuan Zhu, Lijuan Guo, Sen Yang
Article Number: 234
Published online on: 14 April 2026

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Article Open Access

Unveiling the prognostic and immunotherapeutic role of Tregs in lung cancer using integrated analysis of single‑cell and bulk RNA‑sequencing

Hongwei He, Zhiming Xiao, Jijun Xue, Yu Zhang, Jichen Qu, Peng Wu, Qiangjun He
Article Number: 233
Published online on: 14 April 2026

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Review Open Access

Nobiletin in cancer therapy: Emerging insights into multi-target mechanisms, overcoming drug resistance and therapeutic translation (Review)

Yanfang Zhang, Qingcai Li, Wenbin Yu, Bin He, Jiahua Peng, Bin Yao
Article Number: 232
Published online on: 14 April 2026

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Expression of Concern Open Access

[Expression of Concern] Apoptotic effect of gambogic acid in esophageal squamous cell carcinoma cells via suppression of the NF‑κB pathway

Wen-Yue Liu, Xu Wu, Cheng-Quan Liao, Jie Shen, Jun Li
Article Number: 231
Published online on: 14 April 2026

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Article

Pretreatment C‑reactive protein‑triglyceride‑glucose index predicts survival in patients with FLOT‑treated locally advanced gastric and gastroesophageal junction cancer

Ayşegül Dumludağ, Mehmet Torun, Osman Sütçüoğlu
Article Number: 230
Published online on: 09 April 2026

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Case Report

Intravascular large B‑cell lymphoma mimicking an orbital mass lesion and bilateral cavernous sinus syndrome: A case report

Qiong Wu, Yiran Jia, Bentao Yang, Xiaojin He, Hongjuan Liu, Libin Jiang
Article Number: 229
Published online on: 09 April 2026

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Correction Open Access

[Corrigendum] FXR1 promotes proliferation, invasion and migration of hepatocellular carcinoma in vitro and in vivo

Kun Zhao, Jie Gao, Jihua Shi, Chengcheng Shi, Chun Pang, Jie Li, Wenzhi Guo, Shuijun Zhang
Article Number: 228
Published online on: 09 April 2026

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Article Open Access

Role of CDX2 in the prognosis of colorectal cancer across stages 0‑IV

Guojun Tong, Hai Qian, Yuefeng Fei, Sheng Yu, Kun Guo, Wenwen Yu, Jing Li, Sicheng Yan
Article Number: 227
Published online on: 08 April 2026

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Article Open Access

Exploring multiple biomarkers and constructing ferroptosis‑associated competing endogenous RNA networks as dual targets in retinoblastoma

Zhengjia Kang, Gaoqin Liu
Article Number: 226
Published online on: 08 April 2026

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Review Open Access

Role of mesenchymal stem cells and their derived exosomes in cervical cancer: Bidirectional mechanisms and research progress (Review)

Xue Li, Daqing Wang
Article Number: 225
Published online on: 08 April 2026

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Review Open Access

Hypoxia‑inducible factors: Regulatory functions and status as a therapeutic target in gastric cancer (Review)

Jia Xu, Guangzhi Ding, Yiming Wang, Chang Liu
Article Number: 224
Published online on: 08 April 2026

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Article Open Access

Machine learning‑based programmed cell death gene signature for prognosis and drug sensitivity in breast cancer

Nan Wu, Zhongting Fan
Article Number: 223
Published online on: 08 April 2026

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Article Open Access

Assessing the density of lymph node metastasis in various inguinal regions of penile cancer using the nine‑section method: A prospective study

Chen Hu, Longguo Dai, Hongyi Wu, Yu Bai, Jun Li, Haiyang Jiang, Haoli Yin, Ying Bi, Wenzhao Wu, Ruiqian Li, Hong Shi
Article Number: 222
Published online on: 08 April 2026

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Article Open Access

Overexpression and knockdown of 5‑lipoxygenase regulates the migration and invasion of colorectal cancer cells

Xuyang Li, Jiletu Huge, Xiaoling Wang, Jing Zhou, Xiudan Li, Xiaoyan Gao, Tiewei Shi, Chunying Bai
Article Number: 221
Published online on: 08 April 2026

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Case Report

Targeting TROP‑2 in treatment‑resistant non‑small cell lung cancer harboring the KRAS G12C mutation and TROP‑2 upregulation: A case report

Lu Sun, Ying Xiong, Xiaobing Li, Yi Peng
Article Number: 220
Published online on: 08 April 2026

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Article Open Access

Exosomal‑miR‑32‑5p directly targets FOXN2 to regulate the proliferation, migration and apoptosis of uterine corpus endometrial carcinoma via the PI3K/AKT/BCL‑2 pathway

Xin Chen, Huihui Li, Xiang Cheng, Yirong Cai, Guangyi Guo
Article Number: 219
Published online on: 08 April 2026

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Expression of Concern Open Access

[Expression of Concern] PRKACB is downregulated in non‑small cell lung cancer and exogenous PRKACB inhibits proliferation and invasion of LTEP‑A2 cells

Yong Chen, Ying Gao, Ye Tian, Da-Li Tian
Article Number: 218
Published online on: 07 April 2026

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Review Open Access

Lactylation enzymes in cancer: Mechanisms and novel therapeutic approaches (Review)

Guiyang Tang, Hanrong Zuo, Rou Long, Chaohui Zhang, Yufan Lv, Xinyu Luo, Jieya Qiu, Jianhong Zuo
Article Number: 217
Published online on: 02 April 2026

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Case Report Open Access

Comprehensive treatment for intracranial invasive sinonasal intestinal‑type adenocarcinoma with a focus on radiotherapy dosage and immunological combination therapy: A case report

Lianlian Yang, Qian Zhao, Fang Yi, Wenyan Guo, Qiongwen Zhang, Song Zhou, Dong Li, Zhihui Li
Article Number: 216
Published online on: 02 April 2026

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Review Open Access

Biological basis and clinical translation prospects of circulating cell‑free DNA in precision management of breast cancer (Review)

Li-Zhuang Fan, Ai-Lan Xu, Ya-Ru Xu, Luo Yang, Fang Yuan, Xin Nie
Article Number: 215
Published online on: 02 April 2026

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Review Open Access

Cutting‑edge advances in endocrine therapy for breast cancer (Review)

Yumei Dong, Lihua Shao, Qiong Li, Yuexiao Qi, Tingting Liu, Shihong Wei, Haiyan Qi
Article Number: 214
Published online on: 02 April 2026

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Case Report Open Access

Rapidly progressive squamous lung cancer with peripheral blood eosinophilia in a 25-year-old woman: A case report

Mingrui Zhang, Huanfang Fan, Chunxia Sun, Dehui Li, Jiangya Gan, Yun He, Jiaqi Chen
Article Number: 213
Published online on: 02 April 2026

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Article Open Access

Dynamic curve type serves as an effective tool for the diagnosis of benign or malignant non‑mass enhancements on breast MRI

Tara Farooq Kareem, Areege Mustafa Kamal, Munawar Al Nakash
Article Number: 212
Published online on: 02 April 2026

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Article Open Access

Clinical predictors of leptomeningeal metastasis from lung adenocarcinoma based on retrospective analysis

Yunyun Lu, Yi Lu, Yueyue Zhang, Hongyuan Du, Xuan Cao, Dexi Jin, Guofu Chen, Xiaohui Yang
Article Number: 211
Published online on: 01 April 2026

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Expression of Concern Open Access

[Expression of Concern] Delphinidin induces cell cycle arrest and apoptosis in HER‑2 positive breast cancer cell lines by regulating the NF‑κB and MAPK signaling pathways

Ailin Wu, Yanfeng Zhu, Bin Han, Jiayuan Peng, Xiaomin Deng, Wei Chen, Jingchang Du, Yu Ou, Xiaoli Peng, Xiaoping Yu
Article Number: 210
Published online on: 01 April 2026

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Case Report Open Access

Primary thoracic synovial sarcoma in a 45‑year‑old male: A case report and literature review

Baolei Liang, Jichun Zhang, Mingqiang Shen, Cuilian Li, Mingxiao Hou, Yunen Liu, Qingyong Cai
Article Number: 209
Published online on: 31 March 2026

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Expression of Concern Open Access

[Expression of Concern] Pseudomonas aeruginosa‑mannose‑sensitive hema-gglutinin inhibits proliferation and induces apoptosis in a caspase‑dependent manner in human bladder cancer cell lines

Yi-Ping Zhu, Xiao-Jie Bian, Ding-Wei Ye, Xu-Dong Yao, Shi-Lin Zhang, Bo Dai, Yi-Jun Shen
Article Number: 208
Published online on: 31 March 2026

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July-2026 Volume 32 Issue 1

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Expression of Concern Open Access

[Expression of Concern] FHOD1 is upregulated in gastric cancer and promotes the proliferation and invasion of gastric cancer cells

Chengfei Jiang, Binbin Yuan, Bo Hang, Jian-Hua Mao, Xiaoping Zou, Pin Wang
Article Number: 277
Published online on: 29 April 2026

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Review Open Access

Watch‑and‑wait in rectal cancer: A critical appraisal of promise, perils and unresolved contours of organ preservation (Review)

Xinqiang Zhu, Beibei Ge, Linchun Wen, Siwei Shan
Article Number: 276
Published online on: 28 April 2026

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Review Open Access

Multi‑omics profiling of pancreatic neuroendocrine tumors: Interplay of genomic instability and the tumor microenvironment (Review)

Yin Wan, Yingnan Zhang, Philip A. Philip, Herbert Chen, Bassel El‑Rayes, Asfar S. Azmi, Yang Shi
Article Number: 275
Published online on: 28 April 2026

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Article Open Access

SOX2‑positive upper tract urothelial carcinoma: Clinicopathological characteristics and therapeutic implications

Hitomi Yasukawa, Yoshinori Ikehata, Naotaka Nishiyama, Hiroshi Kitamura
Article Number: 274
Published online on: 28 April 2026

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Article Open Access

Diagnostic and therapeutic challenges of locally advanced colon cancer complicated with acute lymphoblastic leukemia: A case report

Yuping Zeng, Song Mu, Guosheng Li, Zhengzi Liang, Qinghua Ji, Yunhuan Zhen, Wenling Wang, Weiwei Chen
Article Number: 273
Published online on: 28 April 2026

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Article Open Access

LINC00184 promotes esophageal squamous cell carcinoma progression via DNMT1‑mediated methylation of the NDRG2 promoter and PI3K/AKT pathway activation

Junjun Guo, Shenbo Fu, Jia Liu, Lina Li, Jin Zhao, Fenggang Wang, Wenan Wu, Xu Chen, Enxiao Li
Article Number: 272
Published online on: 28 April 2026

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Article Open Access

A clear cell sarcoma tumor of the finger with an unusual presentation misdiagnosed as a glomus tumor in an adolescent patient: A case report

Abdulrahman Alaseem, Hatim Khoja, Khalid Murrad, Sarah Alkhalife, Nouf Altwaijri, Abdullah Almawi, Abdulaziz Bin Dakhil, Abdulaziz Alhammad, Banan Alqady, Eman Najjar
Article Number: 271
Published online on: 28 April 2026

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Case Report Open Access

Primary thyroid lymphoma with Hashimoto's thyroiditis: A case report and literature review

Fangshu Liu, Xueya Xin, Kai Tan, Xinv Chen, Chanjuan Shen, Qiuhong Yang
Article Number: 270
Published online on: 28 April 2026

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Expression of Concern Open Access

[Expression of Concern] In vitro and in vivo inhibition of tumor cell viability by combined dihydroartemisinin and doxorubicin treatment, and the underlying mechanism

Xiang Tai, Xiao-Bei Cai, Zhang Zhang, Rui Wei
Article Number: 269
Published online on: 28 April 2026

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