Detection of intravenous leiomyomatosis with intracardiac extension by ultrasonography: A case report

Liu,Wei; Liu,Ming; Xue,Jing

doi:10.3892/ol.2013.1387

August 2013 Volume 6 Issue 2

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August 2013 Volume 6 Issue 2

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Case Report

Detection of intravenous leiomyomatosis with intracardiac extension by ultrasonography: A case report

Authors:
- Wei Liu
- Ming Liu
- Jing Xue
View Affiliations / Copyright

Affiliations: Department of Gynecology, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, Shandong 250012, P.R. China, Department of Gynecology, Shandong University, Jinan, Shandong 250012, P.R. China
Pages: 336-338
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Published online on: June 10, 2013

https://doi.org/10.3892/ol.2013.1387
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Abstract

Intravenous leiomyomatosis (IVL) is characterized by histologically benign tumors that exhibit aggressive clinical behavior. On rare occasions, the tumors may extend into the regional and systemic veins, thus reaching the heart. This may subsequently cause intracardiac leiomyomatosis (ICL), which may lead to congestive heart failure and occasionally, sudden fatalities. Due to its rarity and diffuse symptoms, the misdiagnosis of ICL is common and as a result, the condition may be under-reported. The present study reports a 33-year-old female who was admitted to Shandong Provincial Hospital Affiliated to Shandong University for myomectomy due to a rapidly growing myoma of the uterus. In routine pre-operative abdominal ultrasonography, a moderately sized echoic mass in the right internal iliac vein was observed, which extended to the common iliac vein, the inferior vena cava and the orifice of the right atrium. A presumptive diagnosis of ICL was made. The patient underwent a well-prepared one-stage thoraco-abdominal surgical procedure and the pathological report confirmed ICL. This case illustrates that the early detection of ICL may prevent a potential emergency situation and abdominal ultrasonography may be considered a useful tool in the diagnosis of ICL.

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1.	Lam PM, Lo KW, Yu MY, Wong WS, Lau JY, Arifi AA and Cheung TH: Intravenous leiomyomatosis: two cases with different routes of tumor extension. J Vasc Surg. 39:465–469. 2004. View Article : Google Scholar : PubMed/NCBI
2.	Butler MW and Sanders A: Obstructive shock in a 47 year old female with a deep venous thrombosis due to intravascular leiomyomatosis: a case report. Cases J. 22:81592009.PubMed/NCBI
3.	Du J, Zhao X, Guo D, Li H and Sun B: Intravenous leiomyomatosis of the uterus: a clinicopathologic study of 18 cases, with emphasis on early diagnosis and appropriate treatment strategies. Hum Pathol. 42:1240–1246. 2011. View Article : Google Scholar
4.	To WW, Ngan HY and Collins RJ: Intravenous leiomyomatosis with intracardiac involvement. Int J Gynaecol Obstet. 42:37–40. 1993. View Article : Google Scholar : PubMed/NCBI
5.	Lou YF, Shi XP and Song ZZ: Intravenous leiomyomatosis of the uterus with extension to the right heart. Cardiovasc Ultrasound. 9:252011. View Article : Google Scholar : PubMed/NCBI
6.	Nishida N, Nonoshita A, Kojiro S, Takemoto Y and Kojiro M: Intravenous leiomyomatosis with uterine leiomyoma and adenomyosis: a case presentation and brief comment on the histogenesis. Kurume Med J. 50:173–175. 2003. View Article : Google Scholar : PubMed/NCBI
7.	Kokawa K, Yamoto M, Yata C, Mabuchi Y and Umesaki N: Postmenopausal intravenous leiomyomatosis with high levels of estradiol and estrogen receptor. Obstet Gynecol. 100:1124–1126. 2002. View Article : Google Scholar : PubMed/NCBI
8.	Lo KW and Lau TK: Intracardiac leiomyomatosis. Case report and literature review. Arch Gynecol Obstet. 264:209–210. 2001. View Article : Google Scholar : PubMed/NCBI
9.	Stolf NA, dos Santos GG and Haddad VL: Unusual abdominal tumors with intracardiac extension. Two cases with successful surgical resection. Rev Hosp Clin Fac Med Sao Paulo. 54:159–164. 1999. View Article : Google Scholar : PubMed/NCBI
10.	Kuenen BC, Slee PH, Seldenrijk CA and Wagenaar SS: Intravenous leiomyomatosis complicated by Budd-Chiari syndrome. Postgrad Med J. 72:686–688. 1996. View Article : Google Scholar : PubMed/NCBI
11.	Cohen DT, Oliva E, Hahn PF, Fuller AF Jr and Lee SI: Uterine smooth-muscle tumors with unusual growth patterns: imaging with pathologic correlation. AJR Am J Roentgenol. 188:246–255. 2007. View Article : Google Scholar : PubMed/NCBI
12.	Ling FT, David TE, Merchant N, Yu E and Butany JW: Intracardiac extension of intravenous leiomyomatosis in a pregnant woman: A case report and review of the literature. Can J Cardiol. 16:73–79. 2000.PubMed/NCBI
13.	Tresukosol D, Kudelka AP, Malpica A, Varma DG, Edwards CL and Kavanagh JJ: Leuprolide acetate and intravascular leiomyomatosis. Obstet Gynecol. 86:688–692. 1995. View Article : Google Scholar : PubMed/NCBI
14.	Andrade LA, Torresan RZ, Sales JF Jr, Vicentini R and De Souza GA: Intravenous leiomyomatosis of the uterus. A report of three cases Pathol Oncol Res. 4:44–47. 1998. View Article : Google Scholar

Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Detection of intravenous leiomyomatosis with intracardiac extension by ultrasonography: A case report

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Abstract

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