Photodynamic therapy combined with cryotherapy for the treatment of nodular basal cell carcinoma

Kim,Sung  Ae; Lee,Kyu  Suk; Cho,Jae-We

doi:10.3892/ol.2013.1504

October 2013 Volume 6 Issue 4

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October 2013 Volume 6 Issue 4

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Article

Photodynamic therapy combined with cryotherapy for the treatment of nodular basal cell carcinoma

Authors:
- Sung Ae Kim
- Kyu Suk Lee
- Jae-We Cho
View Affiliations / Copyright

Affiliations: Department of Dermatology, Keimyung University School of Medicine, Dongsan-dong, Jung-gu, Daegu 700-712, Republic of Korea
Pages: 939-941
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Published online on: July 31, 2013

https://doi.org/10.3892/ol.2013.1504
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Abstract

Carbon dioxide (CO2) laser ablation in combination with photodynamic therapy (PDT) has previously been successfully used to treat superficial basal cell carcinoma (BCC). However, the efficacy of this treatment modality is limited in the treatment of deeper lesions and the more aggressive subtypes of BCC. In order to improve the outcome of PDT, 8 BCC lesions of variable depths (4 lesions ≤2 mm and 4 lesions >2 mm) and subtypes (1 superficial, 6 nodular and 1 infiltrative) were treated with CO2 laser ablation in combination with PDT, followed by modified cryotherapy. The mean number of treatment sessions was 1.5 and the follow-up period was 22 months. All of the patients demonstrated a complete response and no recurrence of disease, while the majority of patients were satisfied with the cosmetic results upon follow‑up examination. The combination therapy of CO2 laser ablation with PDT followed by modified cryotherapy demonstrated a good efficacy and satisfactory cosmetic outcomes in the treatment of nodular BCC.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Photodynamic therapy combined with cryotherapy for the treatment of nodular basal cell carcinoma

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